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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
October-2015 Volume 34 Issue 4

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

The complex liaison between cachexia and tumor burden (Review)

Andrea De Lerma Barbaro
Pages: 1635-1649
Published online on: 31 July 2015

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Article Open Access

NOTCH2 signaling confers immature morphology and aggressiveness in human hepatocellular carcinoma cells

Yoshihiro Hayashi, Makoto Osanai, Gang-Hong Lee
Pages: 1650-1658
Published online on: 04 August 2015

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Article Open Access

Selective induction of apoptosis in human gastric cancer cells by Lactobacillus kefiri (PFT), a novel kefir product

Mamdooh Ghoneum, Nouran Felo
Pages: 1659-1666
Published online on: 06 August 2015

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Article Open Access

Impact of reduced levels of APE1 transcripts on the survival of patients with urothelial carcinoma of the bladder

Mariana Chantre-Justino, Gilda Alves, Constança Britto, Angélica Cardoso, Luciano Scherrer, Aline dos Santos Moreira, Raul Quirino, Antonio Ornellas, Alvaro Leitão, Claudia Lage
Pages: 1667-1674
Published online on: 24 July 2015

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Article Open Access

Differential crosstalk between the AMPK and PI3K/Akt pathways in breast cancer cells of differing genotypes: Leptin inhibits the effectiveness of AMPK activation

Omar S. El-Masry, Kaltoom Al-Sakkaf, Barry L. Brown, Pauline R.M. Dobson
Pages: 1675-1680
Published online on: 11 August 2015

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Article Open Access

HOXD10 acts as a tumor-suppressive factor via inhibition of the RHOC/AKT/MAPK pathway in human cholangiocellular carcinoma

Haixia Yang, Jiupeng Zhou, Jianqiang Mi, Ke Ma, Yangwei Fan, Jing Ning, Chuying Wang, Xin Wei, Huadong Zhao, Enxiao Li
Pages: 1681-1691
Published online on: 10 August 2015

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Article Open Access

Nutlin-3 sensitizes nasopharyngeal carcinoma cells to cisplatin-induced cytotoxicity

Yee-Lin Voon, Munirah Ahmad, Pooi-Fong Wong, Roslina Husaini, Wayne Tiong-Weng Ng, Chee-Onn Leong, David Philip Lane, Alan Soo-Beng Khoo
Pages: 1692-1700
Published online on: 05 August 2015

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Article Open Access

Acquirement of DNA copy number variations in non‑small cell lung cancer metastasis to the brain

Fang Li, Libo Sun, Sixun Zhang
Pages: 1701-1707
Published online on: 10 August 2015

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Article

The novel mTOR inhibitor Torin-2 induces autophagy and downregulates the expression of UHRF1 to suppress hepatocarcinoma cell growth

Congren Wang, Xuejin Wang, Zijian Su, Hongjiang Fei, Xiaoyu Liu, Qunxiong Pan
Pages: 1708-1716
Published online on: 23 July 2015

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Article

Significance of expression of glucagon-like peptide 1 receptor in pancreatic cancer

Ana Ines Cases, Takao Ohtsuka, Hideyo Kimura, Biao Zheng, Koji Shindo, Yoshinao Oda, Kazuhiro Mizumoto, Masafumi Nakamura, Masao Tanaka
Pages: 1717-1725
Published online on: 20 July 2015

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Article

Inhibition of NADPH oxidase 4 induces apoptosis in malignant mesothelioma: Role of reactive oxygen species

Motoya Tanaka, Yuji Miura, Hiroki Numanami, Sivasundaram Karnan, Akinobu Ota, Hiroyuki Konishi, Yoshitaka Hosokawa, Masayuki Hanyuda
Pages: 1726-1732
Published online on: 27 July 2015

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Article

Dual effects of human adipose tissue-derived mesenchymal stem cells in human lung adenocarcinoma A549 xenografts and colorectal adenocarcinoma HT-29 xenografts in mice

Jung Joo Rhyu, Jun-Won Yun, Euna Kwon, Jeong-Hwan Che, Byeong-Cheol Kang
Pages: 1733-1744
Published online on: 07 August 2015

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Article

Subpath analysis of each subtype of head and neck cancer based on the regulatory relationship between miRNAs and biological pathways

Fengwei An, Zhiqiang Zhang, Ming Xia, Lijun Xing
Pages: 1745-1754
Published online on: 24 July 2015

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Article

12-Deoxyphorbol 13-palmitate inhibits the expression of VEGF and HIF-1α in MCF-7 cells by blocking the PI3K/Akt/mTOR signaling pathway

Ying Yang, Huan Cong, Cuicui Han, Liling Yue, Haiying Dong, Jicheng Liu
Pages: 1755-1760
Published online on: 31 July 2015

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Article

Galectin-9 suppresses cholangiocarcinoma cell proliferation by inducing apoptosis but not cell cycle arrest

Kiyoyuki Kobayashi, Asahiro Morishita, Hisakazu Iwama, Koji Fujita, Ryoichi Okura, Shintaro Fujihara, Takuma Yamashita, Takayuki Fujimori, Kiyohito Kato, Hideki Kamada, Toshiro Niki, Mitsuomi Hirashima, Keiichi Okano, Yasuyuki Suzuki, Tsutomu Masaki
Pages: 1761-1770
Published online on: 10 August 2015

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Article

microRNA-22 downregulation of galectin-9 influences lymphocyte apoptosis and tumor cell proliferation in liver cancer

Qianqian Yang, Weichao Jiang, Chunbo Zhuang, Zhi Geng, Chen Hou, Da Huang, Lihua Hu, Xiaobei Wang
Pages: 1771-1778
Published online on: 31 July 2015

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Article

Expression profile analysis of microRNAs and downregulated miR-486-5p and miR-30a-5p in non-small cell lung cancer

Jianjie Zhu, Yuanyuan Zeng, Chun Xu, Hualong Qin, Zhe Lei, Dan Shen, Zeyi Liu, Jian-An Huang
Pages: 1779-1786
Published online on: 21 July 2015

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Article

Twist induces epithelial-mesenchymal transition in cervical carcinogenesis by regulating the TGF-β/Smad3 signaling pathway Retraction in /10.3892/or.2025.8960

Qiong Fan, Mei-Ting Qiu, Zhu Zhu, Jin-Hua Zhou, Limo Chen, Ye Zhou, Wei Gu, Li‑Hua Wang, Zhu-Nan Li, Ying Xu, Wei-Wei Cheng, Dan Wu, Wei Bao
Pages: 1787-1794
Published online on: 22 July 2015

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Article

Enhanced therapeutic effects against murine colon carcinoma induced by a Colon 26/Ag85A-CD226 tumor cell vaccine

Yan Li, Fangli Yang, Lixuan Sang, Junfeng Zhu, Xue Han, Fengping Shan, Shengjun Li, Jingbo Zhai, Danan Wang, Changlong Lu, Xun Sun
Pages: 1795-1804
Published online on: 20 July 2015

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Article

Inhibiting GLUT-1 expression and PI3K/Akt signaling using apigenin improves the radiosensitivity of laryngeal carcinoma in vivo

Yang‑Yang Bao, Shui‑Hong Zhou, Zhong‑Jie Lu, Jun Fan, Ya‑Ping Huang
Pages: 1805-1814
Published online on: 28 July 2015

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Article

Expression of cortactin in human gliomas and its effect on migration and invasion of glioma cells

Leilei Wang, Kai Zhao, Bingcheng Ren, Meng Zhu, Chen Zhang, Pengfei Zhao, Hua Zhou, Lei Chen, Shenping Yu, Xuejun Yang
Pages: 1815-1824
Published online on: 28 July 2015

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Article

Targeting effect of PEGylated liposomes modified with the Arg-Gly-Asp sequence on gastric cancer

Jie Ding, Min Feng, Feng Wang, Hao Wang, Wenxian Guan
Pages: 1825-1834
Published online on: 22 July 2015

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Article

Effect of Rab23 on the proliferation and apoptosis in breast cancer

Yali Liu, Chao Zeng, Nandi Bao, Jie Zhao, Yuzhen Hu, Chengxin Li, Sumin Chi
Pages: 1835-1844
Published online on: 24 July 2015

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Article

MicroRNA-144 affects radiotherapy sensitivity by promoting proliferation, migration and invasion of breast cancer cells

Lei Yu, Yanming Yang, Jiguang Hou, Chengwei Zhai, Yunhao Song, Zhiliang Zhang, Ling Qiu, Xiaojing Jia
Pages: 1845-1852
Published online on: 05 August 2015

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Article

Curcumin alters gene expression-associated DNA damage, cell cycle, cell survival and cell migration and invasion in NCI-H460 human lung cancer cells in vitro

I-Tsang Chiang, Wei-Shu Wang, Hsin-Chung Liu, Su-Tso Yang, Nou-Ying Tang, Jing-Gung Chung
Pages: 1853-1874
Published online on: 29 July 2015

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Article

Novel quinazoline derivatives exhibit antitumor activity by inhibiting JAK2/STAT3

Haishi Qiao, Dan Zhao, Hengfei Shi, Ke Ren, Jianxin Li, Erguang Li
Pages: 1875-1882
Published online on: 21 July 2015

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Article

RRM1, TUBB3, TOP2A, CYP19A1, CYP2D6: Difference between mRNA and protein expression in predicting prognosis of breast cancer patients

Ying-Chun Xu, Feng-Chun Zhang, Jun-Jian Li, Jia-Qi Dai, Qiang Liu, Lei Tang, Yue Ma, Qi Xu, Xiao-Lin Lin, Hong-Bin Fan, Hong-Xia Wang
Pages: 1883-1894
Published online on: 07 August 2015

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Article

Inhibitory effects of 3-bromopyruvate in human nasopharyngeal carcinoma cells

Xue Zou, Mengxiao Zhang, Yiming Sun, Surong Zhao, Yingmei Wei, Xudong Zhang, Chenchen Jiang, Hao Liu
Pages: 1895-1904
Published online on: 23 July 2015

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Article

Never in mitosis gene A-related kinase 6 and aurora kinase A: New gene biomarkers in the conversion from ulcerative colitis to colorectal cancer

Emre Gerçeker, Seda Orenay Boyacıoglu, Elmas Kasap, Ahmed Baykan, Hakan Yuceyar, Hatice Yıldırım, Semin Ayhan, Ender Ellidokuz, Mehmet Korkmaz
Pages: 1905-1914
Published online on: 10 August 2015

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Article

Bone marrow-derived mesenchymal stem cells co‑expressing interleukin-18 and interferon-β exhibit potent antitumor effect against intracranial glioma in rats

Gang Xu, Yanwu Guo, Zhiyuan Seng, Gang Cui, Jianqiang Qu
Pages: 1915-1922
Published online on: 05 August 2015

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Article

miR-219-5p plays a tumor suppressive role in colon cancer by targeting oncogene Sall4

Ji Cheng, Rui Deng, Peng Zhang, Chuanqing Wu, Ke Wu, Liang Shi, Xinghua Liu, Jie Bai, Meizhou Deng, Xiaoming Shuai, Jinbo Gao, Guobin Wang, Kaixiong Tao
Pages: 1923-1932
Published online on: 04 August 2015

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Article

Alteration of O-GlcNAcylation affects serine phosphorylation and regulates gene expression and activity of pyruvate kinase M2 in colorectal cancer cells

Parunya Chaiyawat, Daranee Chokchaichamnankit, Kriengsak Lirdprapamongkol, Chantragan Srisomsap, Jisnuson Svasti, Voraratt Champattanachai
Pages: 1933-1942
Published online on: 05 August 2015

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Article

MicroRNA-338 inhibits migration and proliferation by targeting hypoxia-induced factor 1α in nasopharyngeal carcinoma Corrigendum in /10.3892/or.2022.8358

Ying Shan, Xingyu Li, Bo You, Si Shi, Qicheng Zhang, Yiwen You
Pages: 1943-1952
Published online on: 10 August 2015

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Article

Targeted delivery of doxorubicin to breast cancer cells by aptamer functionalized DOTAP/DOPE liposomes

Xingli Song, Yi Ren, Jing Zhang, Gang Wang, Xuedong Han, Wei Zheng, Linlin Zhen
Pages: 1953-1960
Published online on: 17 July 2015

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Article

Prediction of response to preoperative chemoradiotherapy and establishment of individualized therapy in advanced rectal cancer

Toshihiro Nakao, Takashi Iwata, Masanori Hotchi, Kozo Yoshikawa, Jun Higashijima, Masaaki Nishi, Chie Takasu, Shohei Eto, Hiroki Teraoku, Mitsuo Shimada
Pages: 1961-1967
Published online on: 10 August 2015

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Article

Inhibition of carbonic anhydrase IX (CA9) sensitizes renal cell carcinoma to ionizing radiation

Wilhelmina C.M. Duivenvoorden, Sarah N. Hopmans, Daniel Gallino, Thomas Farrell, Carrie Gerdes, Diana Glennie, Himu Lukka, Jehonathan H. Pinthus
Pages: 1968-1976
Published online on: 07 August 2015

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Article

Inhibition of sphingosine-1-phosphate phosphatase 1 promotes cancer cells migration in gastric cancer: Clinical implications Corrigendum in /10.3892/or.2018.6269

Xiang Y. Gao, Lin Li, Xiao H. Wang, Xian Z. Wen, Ke Ji, Lin Ye, Jun Cai, Wen G. Jiang, Jia F. Ji
Pages: 1977-1987
Published online on: 30 July 2015

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Article

MicroRNA-374a promotes esophageal cancer cell proliferation via Axin2 suppression

Yue Wang, Hua Xin, Zhifeng Han, Hongbing Sun, Nan Gao, Haixiang Yu
Pages: 1988-1994
Published online on: 07 August 2015

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Article

Dendritic cells combined with anti-GITR antibody produce antitumor effects in osteosarcoma

Masanori Kawano, Kazuhiro Tanaka, Ichiro Itonaga, Tatsuya Iwasaki, Masashi Miyazaki, Shinichi Ikeda, Hiroshi Tsumura
Pages: 1995-2001
Published online on: 29 July 2015

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Article

Mechanisms and in vitro effects of cepharanthine hydrochloride: Classification analysis of the drug-induced differentially-expressed genes of human nasopharyngeal carcinoma cells

Guanjun Liu, Dongmei Wu, Xinqiang Liang, Huifen Yue, Ying Cui
Pages: 2002-2010
Published online on: 10 August 2015

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Article

NOV inhibits proliferation while promoting apoptosis and migration in osteosarcoma cell lines through p38/MAPK and JNK/MAPK pathways

Juan Yao, Yaguang Weng, Shujuan Yan, Mengyi Hou, Hao Wang, Qiong Shi, Guowei Zuo
Pages: 2011-2021
Published online on: 24 July 2015

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Article

Fusion of cancer stem cells and mesenchymal stem cells contributes to glioma neovascularization

Chao Sun, Dongliang Zhao, Xingliang Dai, Jinsheng Chen, Xiaoci Rong, Haiyang Wang, Aidong Wang, Ming Li, Jun Dong, Qiang Huang, Qing Lan
Pages: 2022-2030
Published online on: 16 July 2015

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Article

Protective effect of neutralizing anti-IL-18α monoclonal antibody on a mouse model of acute graft-versus-host disease

Xiaocui Li, Cuiping Zhang, Wei Chen, Bin Pan, Fanyun Kong, Kuiyang Zheng, Renxian Tang, Lingyu Zeng
Pages: 2031-2039
Published online on: 05 August 2015

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Article

Aqueous extract of Psoralea corylifolia L. inhibits lipopolysaccharide-induced endothelial-mesenchymal transition via downregulation of the NF-κB-SNAIL signaling pathway

Bom Jung, Eun Hyang Jang, Darong Hong, In Hye Cho, Min-Ju Park, Jong-Ho Kim
Pages: 2040-2046
Published online on: 27 July 2015

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Article

Clinicopathological significance of N-cadherin and VEGF in advanced gastric cancer brain metastasis and the effects of metformin in preclinical models

Kyong-Hwa Jun, Jung Eun Lee, Se Hoon Kim, Ji-Han Jung, Hyun‑Joo Choi, Young Il Kim, Hyung-Min Chin, Seung-Ho Yang
Pages: 2047-2053
Published online on: 10 August 2015

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Article

MicroRNA-122 affects cell aggressiveness and apoptosis by targeting PKM2 in human hepatocellular carcinoma Corrigendum in /10.3892/or.2021.8073 Retraction in /10.3892/or.2023.8475

Qiuran Xu, Meiqi Zhang, Jianfeng Tu, Linxiao Pang, Wenwei Cai, Xin Liu
Pages: 2054-2064
Published online on: 05 August 2015

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Article

Valproic acid suppresses the self-renewal and proliferation of head and neck cancer stem cells

Sang Hyuk Lee, Hyo Jung Nam, Hyun Jung Kang, Tina L. Samuels, Nikki Johnston, Young Chang Lim
Pages: 2065-2071
Published online on: 23 July 2015

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Article

Gene expression profiling in myelodysplastic syndrome after SPARC overexpression associated with Ara-C

Qing Nian, Zhiqiang Zhang, Chunmei Wei, Xingyi Kuang, Xingyong Wang, Li Wang
Pages: 2072-2082
Published online on: 20 July 2015

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Article

MG132 enhances the radiosensitivity of lung cancer cells in vitro and in vivo

Wei Zhu, Jing Liu, Jihua Nie, Wenjiong Sheng, Han Cao, Wenhao Shen, Aijing Dong, Jundong Zhou, Yang Jiao, Shuyu Zhang, Jianping Cao
Pages: 2083-2089
Published online on: 04 August 2015

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Article

Hepatitis B virus X protein modifies invasion, proliferation and the inflammatory response in an HTR-8/SVneo cell model

Hong Cui, Qiu-Ling Li, Jing Chen, Quan Na, Cai-Xia Liu
Pages: 2090-2098
Published online on: 05 August 2015

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Article

Expression of immune checkpoint molecules of T cell immunoglobulin and mucin protein 3/galectin-9 for NK cell suppression in human gastrointestinal stromal tumors

Hideo Komita, Shigeo Koido, Kazumi Hayashi, Shin Kan, Masaki Ito, Yuko Kamata, Masafumi Suzuki, Sadamu Homma
Pages: 2099-2105
Published online on: 24 July 2015

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Article

Effect of Raf kinase inhibitor protein expression on malignant biological behavior and progression of colorectal cancer

Yun Wang, Ling-Yun Wang, Fen Feng, Yang Zhao, Ma-Yan Huang, Qiong Shao, Cui Chen, Hui Sheng, Dong-Liang Chen, Zhao-Lei Zeng, Rui-Hua Xu, Yu-Hong Li
Pages: 2106-2114
Published online on: 28 July 2015

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Article

Effect of DR4 promoter methylation on the TRAIL‑induced apoptosis in lung squamous carcinoma cell

Wenwu Wang, Xiaoyan Qi, Minghua Wu
Pages: 2115-2125
Published online on: 04 August 2015

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Article

Enrichment and characterization of cancer stem cells from a human non-small cell lung cancer cell line

Changhong Zhao, Sarra Setrerrahmane, Hanmei Xu
Pages: 2126-2132
Published online on: 30 July 2015

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Article

Simvastatin protects Sertoli cells against cisplatin cytotoxicity through enhanced gap junction intercellular communication

Lingzhi Wang, Jianxin Peng, Huansen Huang, Qin Wang, Meiling Yu, Liang Tao
Pages: 2133-2141
Published online on: 10 August 2015

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Article

Meloxicam combined with sorafenib synergistically inhibits tumor growth of human hepatocellular carcinoma cells via ER stress-related apoptosis

Jingtao Zhong, Peng Xiu, Xiaofeng Dong, Fuhai Wang, Honglong Wei, Xin Wang, Zongzhen Xu, Feng Liu, Tao Li, Yong Wang, Jie Li
Pages: 2142-2150
Published online on: 06 August 2015

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Article

A genetic polymorphism (rs17251221) in the calcium-sensing receptor is associated with ovarian cancer susceptibility

Shi Yan, Cunzhong Yuan, Qifeng Yang, Xiaoyan Li, Ning Yang, Xiaoyan Liu, Ruihua Dong, Xi Zhang, Zeng Yuan, Ning Zhang, Beihua Kong
Pages: 2151-2155
Published online on: 05 August 2015

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Article

Gentian violet inhibits MDA-MB-231 human breast cancer cell proliferation, and reverses the stimulation of osteoclastogenesis and suppression of osteoblast activity induced by cancer cells

Masayoshi Yamaguchi, Tatyana Vikulina, M. Neale Weitzmann
Pages: 2156-2162
Published online on: 10 August 2015

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Article

MicroRNA-205 inhibits the proliferation and invasion of breast cancer by regulating AMOT expression

Haige Zhang, Qingxia Fan
Pages: 2163-2170
Published online on: 23 July 2015

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Article

miR-138 suppresses the proliferation of oral squamous cell carcinoma cells by targeting Yes-associated protein 1

Ran Xu, Guang Zeng, Jing Gao, Yue Ren, Zhe Zhang, Qingna Zhang, Jinxiu Zhao, Hong Tao, Daxu Li
Pages: 2171-2178
Published online on: 23 July 2015

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Article

HGF mediated upregulation of lipocalin 2 regulates MMP9 through nuclear factor-κB activation

Sung Ae Koh, Kyung Hee Lee
Pages: 2179-2187
Published online on: 10 August 2015

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Article

miR-519d-mediated downregulation of STAT3 suppresses breast cancer progression

Xin Deng, Yi Zhao, Baosheng Wang
Pages: 2188-2194
Published online on: 29 July 2015

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Article

MicroRNA-124 suppresses the migration and invasion of osteosarcoma cells via targeting ROR2-mediated non-canonical Wnt signaling Retraction in /10.3892/or.2021.8107

Can Zhang, Yihe Hu, Jun Wan, Hongbo He
Pages: 2195-2201
Published online on: 10 August 2015

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Article

miR-126 inhibits papillary thyroid carcinoma growth by targeting LRP6 Retraction in /10.3892/or.2021.8097

Qiang Wen, Jie Zhao, Lin Bai, Tongtong Wang, Haishan Zhang, Qingjie Ma
Pages: 2202-2210
Published online on: 31 July 2015

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Journal Cover
May-2026 Volume 55 Issue 5

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

ZBTB7A promotes malignant phenotypes in ovarian cancer through transcriptional activation of CRLF1

Xiaobai Hao, Yu Chen
Article Number: 102
Published online on: 24 March 2026

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Article Open Access

MS4322 is a selective protein arginine methyltransferase 5 degrader with antitumor effects in cervical cancer cells

Rui Luo, Jingping Chen, Zhaojie Chen, Surong Wang, Tianfeng Liu, Yang Xu
Article Number: 101
Published online on: 24 March 2026

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Retraction Open Access

[Retracted] Roles of the SNHG7/microRNA‑9‑5p/DPP4 ceRNA network in the growth and 131I resistance of thyroid carcinoma cells through PI3K/Akt activation

Wanzhi Chen, Jichun Yu, Rong Xie, Tao Zhou, Chengfeng Xiong, Shuyong Zhang, Meijun Zhong
Article Number: 100
Published online on: 23 March 2026

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Article Open Access

Andrographis exerts antitumor effects and enhances 5‑FU efficacy via the alteration of ferroptosis‑related genes in esophageal squamous cell carcinoma

Kosuke Yoshimura, Tadanobu Shimura, Ruiya Ma, Yaxuan Huang, Takahito Kitajima, Shinji Yamashita, Yuki Sato, Koki Higashi, Mikio Kawamura, Hiromi Yasuda, Yuhki Koike, Yoshiki Okita, Shigeyuki Yoshiyama, Minako Kobayashi, Masaki Ohi, Hiroki Ohge, Shinya Takahashi, Ajay Goel, Yoshinaga Okugawa, Yuji Toiyama
Article Number: 99
Published online on: 20 March 2026

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Sphingosine‑1‑phosphate receptor 1 enhances olfactory receptor 51E1‑mediated inhibition of proliferation via Src/JNK signaling in prostate cancer cells

Kiheon Kim, Jinwoo Lee, Chulwon Choi, Jungnam Bae, Hee-Jung Choi, Won-Ki Huh
Article Number: 98
Published online on: 19 March 2026

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Review Open Access

Mechanistic insights into the roles of astragalosides and Astragalus polysaccharides in gynecological and breast cancers (Review)

Ruixin Liu, Zhanyu Lin, Yuelin Li, Yuetong Ci, Zhengqi Guo, Zhenguo Xu
Article Number: 97
Published online on: 19 March 2026

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Retraction Open Access

[Retracted] Inhibition of tankyrase 1 in human gastric cancer cells enhances telomere shortening by telomerase inhibitors 

Hao Zhang, Meng-Hua Yang, Jing-Jing Zhao, Ling Chen, Song-Tao Yu, Xu-Dong Tang, Dian-Chun Fang, Shi-Ming Yang
Article Number: 96
Published online on: 16 March 2026

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Article Open Access

Silencing of SIVA‑1 promotes cisplatin resistance in gastric cancer via the Bcl‑2/BAX‑mediated mitochondria‑dependent apoptosis pathway

Zheng-Yi Shi, Zheng-Rong Ding, Yu-Liang Huang, Yuan-Rui Lei, Hai-Bin Huang, Yan Qing, Miao-Ren Deng, Xu-Man Lu, Xu-Dong Dong, Long-Jie Xia, Sheng Xu, Xiao-Gang Zhong, Lei Li, Fan-Biao Kong, Xiao-Tong Wang
Article Number: 95
Published online on: 13 March 2026

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Article Open Access

Depleting HIF‑1α attenuates the progression of osteosarcoma, but tumorigenicity is sustained through HIF‑independent pathways

Ayaka Kunishima, Takatsune Shimizu, Tetsuya Takimoto, Atsunobu Sagara, Hiroyuki Nobusue, Hidetoshi Hasuwa, Shinya Hasegawa, Yuka Tamaoki, Hitomi Miyake, Yumi Fukuchi, Hideyuki Saya, Akihiro Muto
Article Number: 94
Published online on: 12 March 2026

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Article Open Access

Unveiling the role of ANGPT2 in esophageal cancer: A prognostic factor and potential oncogene

Zhigang Zhai, Zhenyu Xue, Yuan Fang, Yixu Fan, Shijiao Li, Yunpeng Yu, Chuansheng Chen, Kaijun Zhang, Deyu Chen, Xiang Tang, Rui Ling
Article Number: 93
Published online on: 12 March 2026

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Article Open Access

POLQ promotes tumor progression and immunosuppression via ATM‑P53 signaling in endometrial cancer

Ningning Zhu, Juanjuan Wang, Xiaoli Zhang, Kai Tang, Lei Gong, Yi Hu
Article Number: 92
Published online on: 11 March 2026

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Correction Open Access

[Corrigendum] 3‑Bromopyruvate and sodium citrate target glycolysis, suppress survivin, and induce mitochondrial‑mediated apoptosis in gastric cancer cells and inhibit gastric orthotopic transplantation tumor growth

Ting-An Wang, Xiao-Dong Zhang, Xing-Yu Guo, Shu-Lin Xian, Yun-Fei Lu
Article Number: 91
Published online on: 11 March 2026

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Review Open Access

Unveiling the molecular landscape: Long non-coding RNAs in neuroblastoma (Review)

Zidong Xia, Huishan Zhai, Lei Zheng, Cheng Wang
Article Number: 90
Published online on: 09 March 2026

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Retraction Open Access

[Retracted] Erastin sensitizes glioblastoma cells to temozolomide by restraining xCT and cystathionine‑γ‑lyase function

Liangyu Chen, Xinxing Li, Libo Liu, Bo Yu, Yixue Xue, Yunhui Liu
Article Number: 89
Published online on: 09 March 2026

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Review Open Access

Advances in the application of frailty scoring in the diagnosis and management of elderly patients with multiple myeloma (Review)

Junlun Liu, Danyu Li, Chao Li, Zhuoren Chen
Article Number: 88
Published online on: 06 March 2026

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Expression of Concern Open Access

[Expression of Concern] c‑Fos/ERK promotes the progression from pancreatic intraepithelial neoplasia to pancreatic ductal adenocarcinoma 

Lei You, Xiaoxia Ren, Yongxing Du, Wenjing Zhao, Ming Cui, Ge Chen, Yupei Zhao
Article Number: 87
Published online on: 05 March 2026

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Review Open Access

CXCL1 in triple‑negative breast cancer: Mechanisms, challenges, and therapeutic opportunities (Review)

Hiba Al Sayegh, Zahraa Assi, Amjad Kanaan, Mirvat El Sibai
Article Number: 86
Published online on: 03 March 2026

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Article Open Access

Cellular and inflammatory characteristics of patient‑derived glioblastoma organoids during in vitro cultivation

Jessica Nojszewski, Nils Oliver Schröder, Jacqueline Clüver, Jonna Holler, Hajrullah Ahmeti, Michael Synowitz, Janka Held-Feindt
Article Number: 85
Published online on: 02 March 2026

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Retraction Open Access

[Retracted] Growth and differentiation factor‑9 promotes adhesive and motile capacity of prostate cancer cells by up‑regulating FAK and Paxillin via Smad dependent pathway 

Sivan M. Bokobza, Lin Ye, Howard G. Kynaston, Wen G. Jiang
Article Number: 84
Published online on: 02 March 2026

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Article Open Access

Platycodin D sensitizes head and neck squamous cell carcinoma to cisplatin by inducing autophagy arrest

Minji Bae, Min Kyeong Lee, Mi Gyeong Jeong, Yeonseo Lee, Harim Joo, Young Chan Lee, Jung Woo Lee, Su Il Kim, Seong-Gyu Ko, Young-Gyu Eun
Article Number: 83
Published online on: 27 February 2026

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Article Open Access

ACSBG1‑driven lipid reprogramming unveiled: A fatty acid metabolism‑associated prognostic model for lung adenocarcinoma

Panxin Hu, Anan Li
Article Number: 82
Published online on: 27 February 2026

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Article Open Access

Knockdown of CCT2 inhibits the malignant progression of hepatocellular carcinoma cells by impairing STAT3 activation

Chao Li, Lei Yang, Yudong Zhang, Baocheng Zhao, Hao Qu
Article Number: 81
Published online on: 25 February 2026

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Retraction Open Access

[Retracted] Songorine suppresses cell growth and metastasis in epithelial ovarian cancer via the Bcl‑2/Bax and GSK3β/β‑catenin signaling pathways

Hongxia Zhang, Ruifeng Dong, Ping Zhang, Yankui Wang
Article Number: 80
Published online on: 25 February 2026

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Journal Cover
June-2026 Volume 55 Issue 6

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

Mechanistic study of MUC3A in promoting progression of clear cell renal cell carcinoma via the JAK‑STAT pathway

Yongyang Yun, Xing Ji, Shuai Hu, Tianyu Wu, Yixiao Liu, Zheng Li, Zhoujie Sun, Peimin Zhou, Lei Yang, Wei Yu
Article Number: 114
Published online on: 14 April 2026

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Perturbation of BRD4 and p300 activity suppresses super enhancer‑driven KLF6 expression in renal carcinoma

Nurul Nadia Mohamad Zamberi, Asmaa Y. Abuhamad, Siti Nur Hasanah Mohd Yusuf, Nur Qurratu Athirah A. Rahman, Mohamad Aimanuddin Mohtar, Saiful Effendi Syafruddin
Article Number: 113
Published online on: 14 April 2026

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Article Open Access

PINK1‑mediated mitophagy enhances breast cancer proliferation through metabolic reprogramming

Zong Jin Guo, Qian Yu, Rui Sha, Wei Li, Hui Juan Dai
Article Number: 112
Published online on: 14 April 2026

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Expression of Concern Open Access

[Expression of Concern] Metformin inhibits growth and sensitizes osteosarcoma cell lines to cisplatin through cell cycle modulation

Irene Quattrini, Amalia Conti, Laura Pazzaglia, Chiara Novello, Stefano Ferrari, Piero Picci, Maria Serena Benassi
Article Number: 111
Published online on: 08 April 2026

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Article Open Access

NF‑κB‑driven LUZP1 promotes metastasis and chemoresistance in head and neck squamous cell carcinoma

Chen-Yuan Lin, Ching-Yun Hsieh, Hsin-Chi Lan, Ching-Chan Lin, Tzu-Ting Chen, Wei-Chi Tseng, Yung-An Tsou, Wei-Chao Chang
Article Number: 110
Published online on: 07 April 2026

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Article Open Access

Hypoxic CAF studies unveil PTHrP‑vitamin D‑RAS axis as pivotal in the CAF

Shoichiro Nakajo, Mamoru Uemura, Hiroshi Kusafuka, Mao Osaki, Chikako Kusunoki, Nobuo Takiguchi, Mitsunobu Takeda, Yuki Sekido, Tsuyoshi Hata, Atsushi Hamabe, Takayuki Ogino, Norikatsu Miyoshi, Mitsuyoshi Tei, Yoshinori Kagawa, Hirofumi Yamamoto, Yuichiro Doki, Hidetoshi Eguchi
Article Number: 109
Published online on: 07 April 2026

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Retraction Open Access

[Retracted] miR‑24‑3p regulates bladder cancer cell proliferation, migration, invasion and autophagy by targeting DEDD

Guoqiang Yu, Zhaohui Jia, Zhongling Dou
Article Number: 108
Published online on: 06 April 2026

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Review Open Access

Role of CHD4 in tumor progression, DNA damage response and treatment resistance (Review)

Shuo Li, Quan Ma, Keying Lian, Zhisheng Jiang, Yun Ma
Article Number: 107
Published online on: 02 April 2026

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Review Open Access

T cell fate regulation in EBV‑associated nasopharyngeal carcinoma (Review)

Liuyang Zhang, Shun Ding, Dongzhui Chen, Benchi Cai, Zhonglin Mu
Article Number: 106
Published online on: 02 April 2026

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Retraction Open Access

[Retracted] Ultrasound‑targeted microbubble destruction‑mediated overexpression of Sirtuin 3 inhibits the progression of ovarian cancer

Li Cheng, Dongmei Zhang, Wei Yan
Article Number: 105
Published online on: 02 April 2026

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Review Open Access

HMGB3: A pivotal orchestrator of therapy resistance and cancer stemness in human malignancies (Review)

Ju Zhang, Yifan Sun, Lanyu Wang, Jiayu Gu, Ye Hua, Jianfeng Shao, Ninghan Feng
Article Number: 104
Published online on: 01 April 2026

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Expression of Concern Open Access

[Expression of Concern] 5‑Azacytidine inhibits the proliferation of bladder cancer cells via reversal of the aberrant hypermethylation of the hepaCAM gene

Xiaorong Wang, E. Chen, Xue Yang, Yin Wang, Zhen Quan, Xiaohou Wu, Chunli Luo
Article Number: 103
Published online on: 30 March 2026

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