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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
October-2015 Volume 34 Issue 4

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

The complex liaison between cachexia and tumor burden (Review)

Andrea De Lerma Barbaro
Pages: 1635-1649
Published online on: 31 July 2015

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Article Open Access

NOTCH2 signaling confers immature morphology and aggressiveness in human hepatocellular carcinoma cells

Yoshihiro Hayashi, Makoto Osanai, Gang-Hong Lee
Pages: 1650-1658
Published online on: 04 August 2015

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Article Open Access

Selective induction of apoptosis in human gastric cancer cells by Lactobacillus kefiri (PFT), a novel kefir product

Mamdooh Ghoneum, Nouran Felo
Pages: 1659-1666
Published online on: 06 August 2015

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Article Open Access

Impact of reduced levels of APE1 transcripts on the survival of patients with urothelial carcinoma of the bladder

Mariana Chantre-Justino, Gilda Alves, Constança Britto, Angélica Cardoso, Luciano Scherrer, Aline dos Santos Moreira, Raul Quirino, Antonio Ornellas, Alvaro Leitão, Claudia Lage
Pages: 1667-1674
Published online on: 24 July 2015

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Article Open Access

Differential crosstalk between the AMPK and PI3K/Akt pathways in breast cancer cells of differing genotypes: Leptin inhibits the effectiveness of AMPK activation

Omar S. El-Masry, Kaltoom Al-Sakkaf, Barry L. Brown, Pauline R.M. Dobson
Pages: 1675-1680
Published online on: 11 August 2015

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Article Open Access

HOXD10 acts as a tumor-suppressive factor via inhibition of the RHOC/AKT/MAPK pathway in human cholangiocellular carcinoma

Haixia Yang, Jiupeng Zhou, Jianqiang Mi, Ke Ma, Yangwei Fan, Jing Ning, Chuying Wang, Xin Wei, Huadong Zhao, Enxiao Li
Pages: 1681-1691
Published online on: 10 August 2015

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Article Open Access

Nutlin-3 sensitizes nasopharyngeal carcinoma cells to cisplatin-induced cytotoxicity

Yee-Lin Voon, Munirah Ahmad, Pooi-Fong Wong, Roslina Husaini, Wayne Tiong-Weng Ng, Chee-Onn Leong, David Philip Lane, Alan Soo-Beng Khoo
Pages: 1692-1700
Published online on: 05 August 2015

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Article Open Access

Acquirement of DNA copy number variations in non‑small cell lung cancer metastasis to the brain

Fang Li, Libo Sun, Sixun Zhang
Pages: 1701-1707
Published online on: 10 August 2015

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Article

The novel mTOR inhibitor Torin-2 induces autophagy and downregulates the expression of UHRF1 to suppress hepatocarcinoma cell growth

Congren Wang, Xuejin Wang, Zijian Su, Hongjiang Fei, Xiaoyu Liu, Qunxiong Pan
Pages: 1708-1716
Published online on: 23 July 2015

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Article

Significance of expression of glucagon-like peptide 1 receptor in pancreatic cancer

Ana Ines Cases, Takao Ohtsuka, Hideyo Kimura, Biao Zheng, Koji Shindo, Yoshinao Oda, Kazuhiro Mizumoto, Masafumi Nakamura, Masao Tanaka
Pages: 1717-1725
Published online on: 20 July 2015

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Article

Inhibition of NADPH oxidase 4 induces apoptosis in malignant mesothelioma: Role of reactive oxygen species

Motoya Tanaka, Yuji Miura, Hiroki Numanami, Sivasundaram Karnan, Akinobu Ota, Hiroyuki Konishi, Yoshitaka Hosokawa, Masayuki Hanyuda
Pages: 1726-1732
Published online on: 27 July 2015

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Article

Dual effects of human adipose tissue-derived mesenchymal stem cells in human lung adenocarcinoma A549 xenografts and colorectal adenocarcinoma HT-29 xenografts in mice

Jung Joo Rhyu, Jun-Won Yun, Euna Kwon, Jeong-Hwan Che, Byeong-Cheol Kang
Pages: 1733-1744
Published online on: 07 August 2015

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Article

Subpath analysis of each subtype of head and neck cancer based on the regulatory relationship between miRNAs and biological pathways

Fengwei An, Zhiqiang Zhang, Ming Xia, Lijun Xing
Pages: 1745-1754
Published online on: 24 July 2015

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Article

12-Deoxyphorbol 13-palmitate inhibits the expression of VEGF and HIF-1α in MCF-7 cells by blocking the PI3K/Akt/mTOR signaling pathway

Ying Yang, Huan Cong, Cuicui Han, Liling Yue, Haiying Dong, Jicheng Liu
Pages: 1755-1760
Published online on: 31 July 2015

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Article

Galectin-9 suppresses cholangiocarcinoma cell proliferation by inducing apoptosis but not cell cycle arrest

Kiyoyuki Kobayashi, Asahiro Morishita, Hisakazu Iwama, Koji Fujita, Ryoichi Okura, Shintaro Fujihara, Takuma Yamashita, Takayuki Fujimori, Kiyohito Kato, Hideki Kamada, Toshiro Niki, Mitsuomi Hirashima, Keiichi Okano, Yasuyuki Suzuki, Tsutomu Masaki
Pages: 1761-1770
Published online on: 10 August 2015

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Article

microRNA-22 downregulation of galectin-9 influences lymphocyte apoptosis and tumor cell proliferation in liver cancer

Qianqian Yang, Weichao Jiang, Chunbo Zhuang, Zhi Geng, Chen Hou, Da Huang, Lihua Hu, Xiaobei Wang
Pages: 1771-1778
Published online on: 31 July 2015

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Article

Expression profile analysis of microRNAs and downregulated miR-486-5p and miR-30a-5p in non-small cell lung cancer

Jianjie Zhu, Yuanyuan Zeng, Chun Xu, Hualong Qin, Zhe Lei, Dan Shen, Zeyi Liu, Jian-An Huang
Pages: 1779-1786
Published online on: 21 July 2015

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Article

Twist induces epithelial-mesenchymal transition in cervical carcinogenesis by regulating the TGF-β/Smad3 signaling pathway Retraction in /10.3892/or.2025.8960

Qiong Fan, Mei-Ting Qiu, Zhu Zhu, Jin-Hua Zhou, Limo Chen, Ye Zhou, Wei Gu, Li‑Hua Wang, Zhu-Nan Li, Ying Xu, Wei-Wei Cheng, Dan Wu, Wei Bao
Pages: 1787-1794
Published online on: 22 July 2015

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Article

Enhanced therapeutic effects against murine colon carcinoma induced by a Colon 26/Ag85A-CD226 tumor cell vaccine

Yan Li, Fangli Yang, Lixuan Sang, Junfeng Zhu, Xue Han, Fengping Shan, Shengjun Li, Jingbo Zhai, Danan Wang, Changlong Lu, Xun Sun
Pages: 1795-1804
Published online on: 20 July 2015

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Article

Inhibiting GLUT-1 expression and PI3K/Akt signaling using apigenin improves the radiosensitivity of laryngeal carcinoma in vivo

Yang‑Yang Bao, Shui‑Hong Zhou, Zhong‑Jie Lu, Jun Fan, Ya‑Ping Huang
Pages: 1805-1814
Published online on: 28 July 2015

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Article

Expression of cortactin in human gliomas and its effect on migration and invasion of glioma cells

Leilei Wang, Kai Zhao, Bingcheng Ren, Meng Zhu, Chen Zhang, Pengfei Zhao, Hua Zhou, Lei Chen, Shenping Yu, Xuejun Yang
Pages: 1815-1824
Published online on: 28 July 2015

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Article

Targeting effect of PEGylated liposomes modified with the Arg-Gly-Asp sequence on gastric cancer

Jie Ding, Min Feng, Feng Wang, Hao Wang, Wenxian Guan
Pages: 1825-1834
Published online on: 22 July 2015

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Article

Effect of Rab23 on the proliferation and apoptosis in breast cancer

Yali Liu, Chao Zeng, Nandi Bao, Jie Zhao, Yuzhen Hu, Chengxin Li, Sumin Chi
Pages: 1835-1844
Published online on: 24 July 2015

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Article

MicroRNA-144 affects radiotherapy sensitivity by promoting proliferation, migration and invasion of breast cancer cells

Lei Yu, Yanming Yang, Jiguang Hou, Chengwei Zhai, Yunhao Song, Zhiliang Zhang, Ling Qiu, Xiaojing Jia
Pages: 1845-1852
Published online on: 05 August 2015

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Article

Curcumin alters gene expression-associated DNA damage, cell cycle, cell survival and cell migration and invasion in NCI-H460 human lung cancer cells in vitro

I-Tsang Chiang, Wei-Shu Wang, Hsin-Chung Liu, Su-Tso Yang, Nou-Ying Tang, Jing-Gung Chung
Pages: 1853-1874
Published online on: 29 July 2015

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Article

Novel quinazoline derivatives exhibit antitumor activity by inhibiting JAK2/STAT3

Haishi Qiao, Dan Zhao, Hengfei Shi, Ke Ren, Jianxin Li, Erguang Li
Pages: 1875-1882
Published online on: 21 July 2015

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Article

RRM1, TUBB3, TOP2A, CYP19A1, CYP2D6: Difference between mRNA and protein expression in predicting prognosis of breast cancer patients

Ying-Chun Xu, Feng-Chun Zhang, Jun-Jian Li, Jia-Qi Dai, Qiang Liu, Lei Tang, Yue Ma, Qi Xu, Xiao-Lin Lin, Hong-Bin Fan, Hong-Xia Wang
Pages: 1883-1894
Published online on: 07 August 2015

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Article

Inhibitory effects of 3-bromopyruvate in human nasopharyngeal carcinoma cells

Xue Zou, Mengxiao Zhang, Yiming Sun, Surong Zhao, Yingmei Wei, Xudong Zhang, Chenchen Jiang, Hao Liu
Pages: 1895-1904
Published online on: 23 July 2015

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Article

Never in mitosis gene A-related kinase 6 and aurora kinase A: New gene biomarkers in the conversion from ulcerative colitis to colorectal cancer

Emre Gerçeker, Seda Orenay Boyacıoglu, Elmas Kasap, Ahmed Baykan, Hakan Yuceyar, Hatice Yıldırım, Semin Ayhan, Ender Ellidokuz, Mehmet Korkmaz
Pages: 1905-1914
Published online on: 10 August 2015

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Article

Bone marrow-derived mesenchymal stem cells co‑expressing interleukin-18 and interferon-β exhibit potent antitumor effect against intracranial glioma in rats

Gang Xu, Yanwu Guo, Zhiyuan Seng, Gang Cui, Jianqiang Qu
Pages: 1915-1922
Published online on: 05 August 2015

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Article

miR-219-5p plays a tumor suppressive role in colon cancer by targeting oncogene Sall4

Ji Cheng, Rui Deng, Peng Zhang, Chuanqing Wu, Ke Wu, Liang Shi, Xinghua Liu, Jie Bai, Meizhou Deng, Xiaoming Shuai, Jinbo Gao, Guobin Wang, Kaixiong Tao
Pages: 1923-1932
Published online on: 04 August 2015

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Article

Alteration of O-GlcNAcylation affects serine phosphorylation and regulates gene expression and activity of pyruvate kinase M2 in colorectal cancer cells

Parunya Chaiyawat, Daranee Chokchaichamnankit, Kriengsak Lirdprapamongkol, Chantragan Srisomsap, Jisnuson Svasti, Voraratt Champattanachai
Pages: 1933-1942
Published online on: 05 August 2015

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Article

MicroRNA-338 inhibits migration and proliferation by targeting hypoxia-induced factor 1α in nasopharyngeal carcinoma Corrigendum in /10.3892/or.2022.8358

Ying Shan, Xingyu Li, Bo You, Si Shi, Qicheng Zhang, Yiwen You
Pages: 1943-1952
Published online on: 10 August 2015

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Article

Targeted delivery of doxorubicin to breast cancer cells by aptamer functionalized DOTAP/DOPE liposomes

Xingli Song, Yi Ren, Jing Zhang, Gang Wang, Xuedong Han, Wei Zheng, Linlin Zhen
Pages: 1953-1960
Published online on: 17 July 2015

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Article

Prediction of response to preoperative chemoradiotherapy and establishment of individualized therapy in advanced rectal cancer

Toshihiro Nakao, Takashi Iwata, Masanori Hotchi, Kozo Yoshikawa, Jun Higashijima, Masaaki Nishi, Chie Takasu, Shohei Eto, Hiroki Teraoku, Mitsuo Shimada
Pages: 1961-1967
Published online on: 10 August 2015

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Article

Inhibition of carbonic anhydrase IX (CA9) sensitizes renal cell carcinoma to ionizing radiation

Wilhelmina C.M. Duivenvoorden, Sarah N. Hopmans, Daniel Gallino, Thomas Farrell, Carrie Gerdes, Diana Glennie, Himu Lukka, Jehonathan H. Pinthus
Pages: 1968-1976
Published online on: 07 August 2015

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Article

Inhibition of sphingosine-1-phosphate phosphatase 1 promotes cancer cells migration in gastric cancer: Clinical implications Corrigendum in /10.3892/or.2018.6269

Xiang Y. Gao, Lin Li, Xiao H. Wang, Xian Z. Wen, Ke Ji, Lin Ye, Jun Cai, Wen G. Jiang, Jia F. Ji
Pages: 1977-1987
Published online on: 30 July 2015

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Article

MicroRNA-374a promotes esophageal cancer cell proliferation via Axin2 suppression

Yue Wang, Hua Xin, Zhifeng Han, Hongbing Sun, Nan Gao, Haixiang Yu
Pages: 1988-1994
Published online on: 07 August 2015

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Article

Dendritic cells combined with anti-GITR antibody produce antitumor effects in osteosarcoma

Masanori Kawano, Kazuhiro Tanaka, Ichiro Itonaga, Tatsuya Iwasaki, Masashi Miyazaki, Shinichi Ikeda, Hiroshi Tsumura
Pages: 1995-2001
Published online on: 29 July 2015

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Article

Mechanisms and in vitro effects of cepharanthine hydrochloride: Classification analysis of the drug-induced differentially-expressed genes of human nasopharyngeal carcinoma cells

Guanjun Liu, Dongmei Wu, Xinqiang Liang, Huifen Yue, Ying Cui
Pages: 2002-2010
Published online on: 10 August 2015

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Article

NOV inhibits proliferation while promoting apoptosis and migration in osteosarcoma cell lines through p38/MAPK and JNK/MAPK pathways

Juan Yao, Yaguang Weng, Shujuan Yan, Mengyi Hou, Hao Wang, Qiong Shi, Guowei Zuo
Pages: 2011-2021
Published online on: 24 July 2015

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Article

Fusion of cancer stem cells and mesenchymal stem cells contributes to glioma neovascularization

Chao Sun, Dongliang Zhao, Xingliang Dai, Jinsheng Chen, Xiaoci Rong, Haiyang Wang, Aidong Wang, Ming Li, Jun Dong, Qiang Huang, Qing Lan
Pages: 2022-2030
Published online on: 16 July 2015

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Article

Protective effect of neutralizing anti-IL-18α monoclonal antibody on a mouse model of acute graft-versus-host disease

Xiaocui Li, Cuiping Zhang, Wei Chen, Bin Pan, Fanyun Kong, Kuiyang Zheng, Renxian Tang, Lingyu Zeng
Pages: 2031-2039
Published online on: 05 August 2015

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Article

Aqueous extract of Psoralea corylifolia L. inhibits lipopolysaccharide-induced endothelial-mesenchymal transition via downregulation of the NF-κB-SNAIL signaling pathway

Bom Jung, Eun Hyang Jang, Darong Hong, In Hye Cho, Min-Ju Park, Jong-Ho Kim
Pages: 2040-2046
Published online on: 27 July 2015

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Article

Clinicopathological significance of N-cadherin and VEGF in advanced gastric cancer brain metastasis and the effects of metformin in preclinical models

Kyong-Hwa Jun, Jung Eun Lee, Se Hoon Kim, Ji-Han Jung, Hyun‑Joo Choi, Young Il Kim, Hyung-Min Chin, Seung-Ho Yang
Pages: 2047-2053
Published online on: 10 August 2015

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Article

MicroRNA-122 affects cell aggressiveness and apoptosis by targeting PKM2 in human hepatocellular carcinoma Corrigendum in /10.3892/or.2021.8073 Retraction in /10.3892/or.2023.8475

Qiuran Xu, Meiqi Zhang, Jianfeng Tu, Linxiao Pang, Wenwei Cai, Xin Liu
Pages: 2054-2064
Published online on: 05 August 2015

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Article

Valproic acid suppresses the self-renewal and proliferation of head and neck cancer stem cells

Sang Hyuk Lee, Hyo Jung Nam, Hyun Jung Kang, Tina L. Samuels, Nikki Johnston, Young Chang Lim
Pages: 2065-2071
Published online on: 23 July 2015

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Article

Gene expression profiling in myelodysplastic syndrome after SPARC overexpression associated with Ara-C

Qing Nian, Zhiqiang Zhang, Chunmei Wei, Xingyi Kuang, Xingyong Wang, Li Wang
Pages: 2072-2082
Published online on: 20 July 2015

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Article

MG132 enhances the radiosensitivity of lung cancer cells in vitro and in vivo

Wei Zhu, Jing Liu, Jihua Nie, Wenjiong Sheng, Han Cao, Wenhao Shen, Aijing Dong, Jundong Zhou, Yang Jiao, Shuyu Zhang, Jianping Cao
Pages: 2083-2089
Published online on: 04 August 2015

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Article

Hepatitis B virus X protein modifies invasion, proliferation and the inflammatory response in an HTR-8/SVneo cell model

Hong Cui, Qiu-Ling Li, Jing Chen, Quan Na, Cai-Xia Liu
Pages: 2090-2098
Published online on: 05 August 2015

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Article

Expression of immune checkpoint molecules of T cell immunoglobulin and mucin protein 3/galectin-9 for NK cell suppression in human gastrointestinal stromal tumors

Hideo Komita, Shigeo Koido, Kazumi Hayashi, Shin Kan, Masaki Ito, Yuko Kamata, Masafumi Suzuki, Sadamu Homma
Pages: 2099-2105
Published online on: 24 July 2015

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Article

Effect of Raf kinase inhibitor protein expression on malignant biological behavior and progression of colorectal cancer

Yun Wang, Ling-Yun Wang, Fen Feng, Yang Zhao, Ma-Yan Huang, Qiong Shao, Cui Chen, Hui Sheng, Dong-Liang Chen, Zhao-Lei Zeng, Rui-Hua Xu, Yu-Hong Li
Pages: 2106-2114
Published online on: 28 July 2015

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Article

Effect of DR4 promoter methylation on the TRAIL‑induced apoptosis in lung squamous carcinoma cell

Wenwu Wang, Xiaoyan Qi, Minghua Wu
Pages: 2115-2125
Published online on: 04 August 2015

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Article

Enrichment and characterization of cancer stem cells from a human non-small cell lung cancer cell line

Changhong Zhao, Sarra Setrerrahmane, Hanmei Xu
Pages: 2126-2132
Published online on: 30 July 2015

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Article

Simvastatin protects Sertoli cells against cisplatin cytotoxicity through enhanced gap junction intercellular communication

Lingzhi Wang, Jianxin Peng, Huansen Huang, Qin Wang, Meiling Yu, Liang Tao
Pages: 2133-2141
Published online on: 10 August 2015

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Article

Meloxicam combined with sorafenib synergistically inhibits tumor growth of human hepatocellular carcinoma cells via ER stress-related apoptosis

Jingtao Zhong, Peng Xiu, Xiaofeng Dong, Fuhai Wang, Honglong Wei, Xin Wang, Zongzhen Xu, Feng Liu, Tao Li, Yong Wang, Jie Li
Pages: 2142-2150
Published online on: 06 August 2015

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Article

A genetic polymorphism (rs17251221) in the calcium-sensing receptor is associated with ovarian cancer susceptibility

Shi Yan, Cunzhong Yuan, Qifeng Yang, Xiaoyan Li, Ning Yang, Xiaoyan Liu, Ruihua Dong, Xi Zhang, Zeng Yuan, Ning Zhang, Beihua Kong
Pages: 2151-2155
Published online on: 05 August 2015

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Article

Gentian violet inhibits MDA-MB-231 human breast cancer cell proliferation, and reverses the stimulation of osteoclastogenesis and suppression of osteoblast activity induced by cancer cells

Masayoshi Yamaguchi, Tatyana Vikulina, M. Neale Weitzmann
Pages: 2156-2162
Published online on: 10 August 2015

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Article

MicroRNA-205 inhibits the proliferation and invasion of breast cancer by regulating AMOT expression

Haige Zhang, Qingxia Fan
Pages: 2163-2170
Published online on: 23 July 2015

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Article

miR-138 suppresses the proliferation of oral squamous cell carcinoma cells by targeting Yes-associated protein 1

Ran Xu, Guang Zeng, Jing Gao, Yue Ren, Zhe Zhang, Qingna Zhang, Jinxiu Zhao, Hong Tao, Daxu Li
Pages: 2171-2178
Published online on: 23 July 2015

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Article

HGF mediated upregulation of lipocalin 2 regulates MMP9 through nuclear factor-κB activation

Sung Ae Koh, Kyung Hee Lee
Pages: 2179-2187
Published online on: 10 August 2015

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Article

miR-519d-mediated downregulation of STAT3 suppresses breast cancer progression

Xin Deng, Yi Zhao, Baosheng Wang
Pages: 2188-2194
Published online on: 29 July 2015

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Article

MicroRNA-124 suppresses the migration and invasion of osteosarcoma cells via targeting ROR2-mediated non-canonical Wnt signaling Retraction in /10.3892/or.2021.8107

Can Zhang, Yihe Hu, Jun Wan, Hongbo He
Pages: 2195-2201
Published online on: 10 August 2015

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Article

miR-126 inhibits papillary thyroid carcinoma growth by targeting LRP6 Retraction in /10.3892/or.2021.8097

Qiang Wen, Jie Zhao, Lin Bai, Tongtong Wang, Haishan Zhang, Qingjie Ma
Pages: 2202-2210
Published online on: 31 July 2015

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Journal Cover
March-2026 Volume 55 Issue 3

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Collaborative breakthroughs in precision diagnosis and treatment of nasopharyngeal cancer: Biomarker‑driven screening and endoscopic minimally invasive surgery reshape the new paradigm of early intervention (Review)

E Jin, Wang Lin, Xiandong Zeng
Article Number: 53
Published online on: 23 January 2026

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Review Open Access

Key immune cells in the tumor immune microenvironment of colorectal cancer: Roles and research advances (Review)

Ming Qiu, Chongyuan Lan, Minglin Lin, Hui Ma
Article Number: 52
Published online on: 21 January 2026

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Correction Open Access

[Corrigendum] Icaritin acts synergistically with epirubicin to suppress bladder cancer growth through inhibition of autophagy

Xiu-Wu Pan, Lin Li, Yi Huang, Hai Huang, Dan-Feng Xu, Yi Gao, Lu Chen, Ji-Zhong Ren, Jian-Wei Cao, Yi Hong, Xin-Gang Cui
Article Number: 51
Published online on: 21 January 2026

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Review Open Access

Epigenetic mechanisms and therapeutic advances in diffuse midline glioma (Review)

Wenbo Wu, Wenlin Chen, Wenbin Ma, Yu Wang
Article Number: 50
Published online on: 20 January 2026

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Review Open Access

Recapitulating lung cancer metastasis in vitro: Advances in organoid models and challenges in clinical translation (Review)

Jian Jiang, Guomin Dong, Zhiyun Zhang, Xiaoyuan Lei, Fanshu Huang, Suoni Li, Jiequn Ma, Jie Bai, Qian Ge, Hui Wei, Zheng Zhao
Article Number: 49
Published online on: 20 January 2026

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Article Open Access

GPR176 enhances the epithelial‑mesenchymal transition in gastric cancer cells by activating the PI3K/AKT/mTOR signaling pathway

Guangchuan Mu, Kaiyan Li, Chaozhen Hu, Jintao Cai, Huichao Ruan, Guanyu Zhu, Dang Liu
Article Number: 48
Published online on: 19 January 2026

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Article Open Access

HMBOX1 inhibits hepatocellular carcinoma progression via PTPN1 mediated AKT1 phosphorylation

Chenning Zhang, Yu Jiang, Jiahui Liu, Wenyu Zhang, Jie Qi, Qing Wen, Hengli Zhao
Article Number: 47
Published online on: 19 January 2026

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Retraction Open Access

[Retracted] Prognostic significance of miR‑218 in human hepatocellular carcinoma and its role in cell growth

Kangsheng Tu, Chao Li, Xin Zheng, Wei Yang, Yingmin Yao, Qingguang Liu
Article Number: 46
Published online on: 19 January 2026

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Review Open Access

Tumor microenvironment in bone sarcomas: Implications for immunotherapy and emerging therapeutic vulnerabilities (Review)

Wentao Li, Lijun Lv, Yibin Jin, Xin Yuan
Article Number: 45
Published online on: 16 January 2026

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Review Open Access

Immunotherapy after EGFR‑TKI treatment in advanced non‑small cell lung cancer: Current status and future perspectives (Review)

Huiyuan Ma, Longhui Li, Conghan Jiao, Yanyan Cheng, Jiayu He, Chen Jiang, Qian Tong, Dan Yi, Ying Zhang
Article Number: 44
Published online on: 16 January 2026

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Correction Open Access

[Corrigendum] Triptolide inhibits JAK2/STAT3 signaling and induces lethal autophagy through ROS generation in cisplatin‑resistant SKOV3/DDP ovarian cancer cells

Yanying Zhong, Fuyin Le, Jiao Cheng, Chen Luo, Xiali Zhang, Xingwu Wu, Fang Xu, Qi Zuo, Buzhen Tan
Article Number: 43
Published online on: 13 January 2026

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Review Open Access

Role of tumor‑infiltrating lymphocytes and miR‑155 in breast cancer: Insights into carcinogenesis and their potential as prognostic biomarkers (Review)

Miriam Monteiro Alvares‑Vilela, Franciele Schlemmer, Sabrina Simplício de Araújo Romero Ferrari, Mary-Ann Elvina Xavier, Ricardo Titze‑de‑Almeida
Article Number: 42
Published online on: 14 January 2026

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Article Open Access

CDK1 depletion suppresses glioma malignancy through cell cycle pathway regulation: Mechanistic insights from functional and molecular profiling

Yu Wang, Huandi Zhou, Xuetao Han, Dongdong Zhang, Liubing Hou, Haonan Li, Tianyi Fan, Sijie Li, Xiaoying Xue
Article Number: 41
Published online on: 12 January 2026

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Retraction Open Access

[Retracted] Downregulated microRNA‑200a promotes EMT and tumor growth through the Wnt/β‑catenin pathway by targeting the E‑cadherin repressors ZEB1/ZEB2 in gastric adenocarcinoma

Ningning Cong, Ping Du, Anling Zhang, Fajuan Shen, Juan Su, Peiyu Pu, Tao Wang, Jie Zjang, Chunsheng Kang, Qingyu Zhang
Article Number: 40
Published online on: 12 January 2026

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Review Open Access

Advances in targeting KRAS mutations: A promising approach for the treatment of non‑small cell lung cancer (Review)

Upesh Sharma, Jincheng Song, Hemraj Kandu, Yue Zhu, Zhaoxia Dai
Article Number: 39
Published online on: 08 January 2026

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Correction Open Access

[Corrigendum] CXCR6 predicts poor prognosis in gastric cancer and promotes tumor metastasis through epithelial-mesenchymal transition

Jie-Jie Jin, Fa-Xiang Dai, Zi-Wen Long, Hong Cai, Xiao-Wen Liu, Ye Zhou, Qi Hong, Qiong-Zhu Dong, Ya-Nong Wang, Hua Huang
Article Number: 38
Published online on: 05 January 2026

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Journal Cover
April-2026 Volume 55 Issue 4

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Correction Open Access

[Corrigendum] Hypoxia and macrophages promote glioblastoma invasion by the CCL4‑CCR5 axis

Ying Wang, Tao Liu, Ning Yang, Shuo Xu, Xingang Li, Donghai Wang
Article Number: 65
Published online on: 04 February 2026

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Origin dictates function: The dual roles of exosomes derived from diverse origins in the onset and progression of colorectal cancer (Review)

Zhao Guo, Haoyan Zhuang, Qingfeng Liu
Article Number: 64
Published online on: 03 February 2026

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Quercetin reduces expression of ATP‑binding cassette transporters by regulating the PTEN/PI3K/AKT signaling pathway in breast cancer cells

Wentao Fu, Leying Lin, Jie Li, Fei Qin, Chuan Chen, Yinglian Cai, Yilun Cai, Yiling Huang, Wang Yang, Shanshan Zhu
Article Number: 63
Published online on: 02 February 2026

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POSTN+ fibroblast‑secreted small extracellular vesicles drive macrophage M2 polarization through BMP4/BMPR2/Smad signaling

Chenyang Zhang, Si Chen, Chenghui Qian, Wanqi Lv, Qian Zhang, Yanjin Wang, Yuqiong Wu, Xue Liu
Article Number: 62
Published online on: 02 February 2026

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[Retracted] EGFR/HER2 inhibitors effectively reduce the malignant potential of MDR breast cancer evoked by P‑gp substrates in vitro and in vivo

Yiting Jin, Wei Zhang, Hongying Wang, Zijing Zhang, Chengyu Chu, Xiuping Liu, Qiang Zou
Article Number: 61
Published online on: 02 February 2026

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Article

Tumor‑associated glucocorticoid inhibition by mifepristone reduces polymorphonuclear myeloid‑derived suppressor cells and promotes antitumor immunity in triple‑negative breast cancer‑bearing mice

Masato Kobayashi, Chisana Konno, Ayato Shimizu, Masanori Kobayashi, Tatsuya Hori
Article Number: 60
Published online on: 30 January 2026

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Review Open Access

Mitochondria in T‑cell tumor immunity and tumor therapies targeting mitochondria (Review)

Minjie Zhou, Yijie Xie, Zhipeng Liu, Yi He, Yibing Yin, Keyu Chen, Zhengyu Zhao, Chengshun Zhang, Dingjun Cai
Article Number: 59
Published online on: 29 January 2026

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TRIM46 deficiency‑induced DNA damage enhances the sensitivity of cisplatin in non‑small cell lung cancer by regulating the Akt signaling pathway

Song Jin, Dandan Zhang, Zhicheng Liao, Lingpei Yu, Yuanyuan Wang, Pengcheng Jia, Minmin Pan, Yifan Li, Jizhou Zhang
Article Number: 58
Published online on: 28 January 2026

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Review Open Access

Advances in isolation and detection technologies and immunotherapy applications of circulating tumor cells (Review)

Ping Zhou, Qin Ye, Yiyun Huang, Yumei Feng, Li Zhou, Ke Xie
Article Number: 57
Published online on: 28 January 2026

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Correction Open Access

[Corrigendum] 3‑Bromopyruvate sensitizes human breast cancer cells to TRAIL‑induced apoptosis via the phosphorylated AMPK‑mediated upregulation of DR5

Yuzhong Chen, Li Wei, Xiaojing Zhang, Xianfu Liu, Yansong Chen, Song Zhang, Lanzhu Zhou, Qixiang Li, Qiong Pan, Surong Zhao, Hao Liu
Article Number: 56
Published online on: 28 January 2026

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High RMI1 expression is associated with cancer cell progression and poor prognosis in prostate cancer

Pengliang Shen, Xiaosong Wang, Xiaoting Yan, Hongyang Du, Bo Wu, Xiaoming Cao
Article Number: 55
Published online on: 27 January 2026

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Retraction Open Access

[Retracted] MicroRNA‑615‑5p targets insulin‑like growth factor 2 and exerts tumor‑suppressing functions in human esophageal squamous cell carcinoma

Bingyin Yang, Rui Xie, Shang-Nong Wu, Cheng-Cheng Gao, Xiao-Zhong Yang, Jing-Fang Zhou
Article Number: 54
Published online on: 26 January 2026

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