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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
October-2015 Volume 34 Issue 4

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Journal Metrics

Impact Factor: 3.9

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

The complex liaison between cachexia and tumor burden (Review)

Andrea De Lerma Barbaro
Pages: 1635-1649
Published online on: 31 July 2015

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Article Open Access

NOTCH2 signaling confers immature morphology and aggressiveness in human hepatocellular carcinoma cells

Yoshihiro Hayashi, Makoto Osanai, Gang-Hong Lee
Pages: 1650-1658
Published online on: 04 August 2015

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Article Open Access

Selective induction of apoptosis in human gastric cancer cells by Lactobacillus kefiri (PFT), a novel kefir product

Mamdooh Ghoneum, Nouran Felo
Pages: 1659-1666
Published online on: 06 August 2015

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Article Open Access

Impact of reduced levels of APE1 transcripts on the survival of patients with urothelial carcinoma of the bladder

Mariana Chantre-Justino, Gilda Alves, Constança Britto, Angélica Cardoso, Luciano Scherrer, Aline dos Santos Moreira, Raul Quirino, Antonio Ornellas, Alvaro Leitão, Claudia Lage
Pages: 1667-1674
Published online on: 24 July 2015

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Article Open Access

Differential crosstalk between the AMPK and PI3K/Akt pathways in breast cancer cells of differing genotypes: Leptin inhibits the effectiveness of AMPK activation

Omar S. El-Masry, Kaltoom Al-Sakkaf, Barry L. Brown, Pauline R.M. Dobson
Pages: 1675-1680
Published online on: 11 August 2015

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Article Open Access

HOXD10 acts as a tumor-suppressive factor via inhibition of the RHOC/AKT/MAPK pathway in human cholangiocellular carcinoma

Haixia Yang, Jiupeng Zhou, Jianqiang Mi, Ke Ma, Yangwei Fan, Jing Ning, Chuying Wang, Xin Wei, Huadong Zhao, Enxiao Li
Pages: 1681-1691
Published online on: 10 August 2015

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Article Open Access

Nutlin-3 sensitizes nasopharyngeal carcinoma cells to cisplatin-induced cytotoxicity

Yee-Lin Voon, Munirah Ahmad, Pooi-Fong Wong, Roslina Husaini, Wayne Tiong-Weng Ng, Chee-Onn Leong, David Philip Lane, Alan Soo-Beng Khoo
Pages: 1692-1700
Published online on: 05 August 2015

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Article Open Access

Acquirement of DNA copy number variations in non‑small cell lung cancer metastasis to the brain

Fang Li, Libo Sun, Sixun Zhang
Pages: 1701-1707
Published online on: 10 August 2015

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Article

The novel mTOR inhibitor Torin-2 induces autophagy and downregulates the expression of UHRF1 to suppress hepatocarcinoma cell growth

Congren Wang, Xuejin Wang, Zijian Su, Hongjiang Fei, Xiaoyu Liu, Qunxiong Pan
Pages: 1708-1716
Published online on: 23 July 2015

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Article

Significance of expression of glucagon-like peptide 1 receptor in pancreatic cancer

Ana Ines Cases, Takao Ohtsuka, Hideyo Kimura, Biao Zheng, Koji Shindo, Yoshinao Oda, Kazuhiro Mizumoto, Masafumi Nakamura, Masao Tanaka
Pages: 1717-1725
Published online on: 20 July 2015

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Article

Inhibition of NADPH oxidase 4 induces apoptosis in malignant mesothelioma: Role of reactive oxygen species

Motoya Tanaka, Yuji Miura, Hiroki Numanami, Sivasundaram Karnan, Akinobu Ota, Hiroyuki Konishi, Yoshitaka Hosokawa, Masayuki Hanyuda
Pages: 1726-1732
Published online on: 27 July 2015

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Article

Dual effects of human adipose tissue-derived mesenchymal stem cells in human lung adenocarcinoma A549 xenografts and colorectal adenocarcinoma HT-29 xenografts in mice

Jung Joo Rhyu, Jun-Won Yun, Euna Kwon, Jeong-Hwan Che, Byeong-Cheol Kang
Pages: 1733-1744
Published online on: 07 August 2015

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Article

Subpath analysis of each subtype of head and neck cancer based on the regulatory relationship between miRNAs and biological pathways

Fengwei An, Zhiqiang Zhang, Ming Xia, Lijun Xing
Pages: 1745-1754
Published online on: 24 July 2015

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Article

12-Deoxyphorbol 13-palmitate inhibits the expression of VEGF and HIF-1α in MCF-7 cells by blocking the PI3K/Akt/mTOR signaling pathway

Ying Yang, Huan Cong, Cuicui Han, Liling Yue, Haiying Dong, Jicheng Liu
Pages: 1755-1760
Published online on: 31 July 2015

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Article

Galectin-9 suppresses cholangiocarcinoma cell proliferation by inducing apoptosis but not cell cycle arrest

Kiyoyuki Kobayashi, Asahiro Morishita, Hisakazu Iwama, Koji Fujita, Ryoichi Okura, Shintaro Fujihara, Takuma Yamashita, Takayuki Fujimori, Kiyohito Kato, Hideki Kamada, Toshiro Niki, Mitsuomi Hirashima, Keiichi Okano, Yasuyuki Suzuki, Tsutomu Masaki
Pages: 1761-1770
Published online on: 10 August 2015

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Article

microRNA-22 downregulation of galectin-9 influences lymphocyte apoptosis and tumor cell proliferation in liver cancer

Qianqian Yang, Weichao Jiang, Chunbo Zhuang, Zhi Geng, Chen Hou, Da Huang, Lihua Hu, Xiaobei Wang
Pages: 1771-1778
Published online on: 31 July 2015

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Article

Expression profile analysis of microRNAs and downregulated miR-486-5p and miR-30a-5p in non-small cell lung cancer

Jianjie Zhu, Yuanyuan Zeng, Chun Xu, Hualong Qin, Zhe Lei, Dan Shen, Zeyi Liu, Jian-An Huang
Pages: 1779-1786
Published online on: 21 July 2015

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Article

Twist induces epithelial-mesenchymal transition in cervical carcinogenesis by regulating the TGF-β/Smad3 signaling pathway Retraction in /10.3892/or.2025.8960

Qiong Fan, Mei-Ting Qiu, Zhu Zhu, Jin-Hua Zhou, Limo Chen, Ye Zhou, Wei Gu, Li‑Hua Wang, Zhu-Nan Li, Ying Xu, Wei-Wei Cheng, Dan Wu, Wei Bao
Pages: 1787-1794
Published online on: 22 July 2015

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Article

Enhanced therapeutic effects against murine colon carcinoma induced by a Colon 26/Ag85A-CD226 tumor cell vaccine

Yan Li, Fangli Yang, Lixuan Sang, Junfeng Zhu, Xue Han, Fengping Shan, Shengjun Li, Jingbo Zhai, Danan Wang, Changlong Lu, Xun Sun
Pages: 1795-1804
Published online on: 20 July 2015

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Article

Inhibiting GLUT-1 expression and PI3K/Akt signaling using apigenin improves the radiosensitivity of laryngeal carcinoma in vivo

Yang‑Yang Bao, Shui‑Hong Zhou, Zhong‑Jie Lu, Jun Fan, Ya‑Ping Huang
Pages: 1805-1814
Published online on: 28 July 2015

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Article

Expression of cortactin in human gliomas and its effect on migration and invasion of glioma cells

Leilei Wang, Kai Zhao, Bingcheng Ren, Meng Zhu, Chen Zhang, Pengfei Zhao, Hua Zhou, Lei Chen, Shenping Yu, Xuejun Yang
Pages: 1815-1824
Published online on: 28 July 2015

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Article

Targeting effect of PEGylated liposomes modified with the Arg-Gly-Asp sequence on gastric cancer

Jie Ding, Min Feng, Feng Wang, Hao Wang, Wenxian Guan
Pages: 1825-1834
Published online on: 22 July 2015

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Article

Effect of Rab23 on the proliferation and apoptosis in breast cancer

Yali Liu, Chao Zeng, Nandi Bao, Jie Zhao, Yuzhen Hu, Chengxin Li, Sumin Chi
Pages: 1835-1844
Published online on: 24 July 2015

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Article

MicroRNA-144 affects radiotherapy sensitivity by promoting proliferation, migration and invasion of breast cancer cells

Lei Yu, Yanming Yang, Jiguang Hou, Chengwei Zhai, Yunhao Song, Zhiliang Zhang, Ling Qiu, Xiaojing Jia
Pages: 1845-1852
Published online on: 05 August 2015

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Article

Curcumin alters gene expression-associated DNA damage, cell cycle, cell survival and cell migration and invasion in NCI-H460 human lung cancer cells in vitro

I-Tsang Chiang, Wei-Shu Wang, Hsin-Chung Liu, Su-Tso Yang, Nou-Ying Tang, Jing-Gung Chung
Pages: 1853-1874
Published online on: 29 July 2015

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Article

Novel quinazoline derivatives exhibit antitumor activity by inhibiting JAK2/STAT3

Haishi Qiao, Dan Zhao, Hengfei Shi, Ke Ren, Jianxin Li, Erguang Li
Pages: 1875-1882
Published online on: 21 July 2015

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Article

RRM1, TUBB3, TOP2A, CYP19A1, CYP2D6: Difference between mRNA and protein expression in predicting prognosis of breast cancer patients

Ying-Chun Xu, Feng-Chun Zhang, Jun-Jian Li, Jia-Qi Dai, Qiang Liu, Lei Tang, Yue Ma, Qi Xu, Xiao-Lin Lin, Hong-Bin Fan, Hong-Xia Wang
Pages: 1883-1894
Published online on: 07 August 2015

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Article

Inhibitory effects of 3-bromopyruvate in human nasopharyngeal carcinoma cells

Xue Zou, Mengxiao Zhang, Yiming Sun, Surong Zhao, Yingmei Wei, Xudong Zhang, Chenchen Jiang, Hao Liu
Pages: 1895-1904
Published online on: 23 July 2015

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Article

Never in mitosis gene A-related kinase 6 and aurora kinase A: New gene biomarkers in the conversion from ulcerative colitis to colorectal cancer

Emre Gerçeker, Seda Orenay Boyacıoglu, Elmas Kasap, Ahmed Baykan, Hakan Yuceyar, Hatice Yıldırım, Semin Ayhan, Ender Ellidokuz, Mehmet Korkmaz
Pages: 1905-1914
Published online on: 10 August 2015

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Article

Bone marrow-derived mesenchymal stem cells co‑expressing interleukin-18 and interferon-β exhibit potent antitumor effect against intracranial glioma in rats

Gang Xu, Yanwu Guo, Zhiyuan Seng, Gang Cui, Jianqiang Qu
Pages: 1915-1922
Published online on: 05 August 2015

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Article

miR-219-5p plays a tumor suppressive role in colon cancer by targeting oncogene Sall4

Ji Cheng, Rui Deng, Peng Zhang, Chuanqing Wu, Ke Wu, Liang Shi, Xinghua Liu, Jie Bai, Meizhou Deng, Xiaoming Shuai, Jinbo Gao, Guobin Wang, Kaixiong Tao
Pages: 1923-1932
Published online on: 04 August 2015

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Article

Alteration of O-GlcNAcylation affects serine phosphorylation and regulates gene expression and activity of pyruvate kinase M2 in colorectal cancer cells

Parunya Chaiyawat, Daranee Chokchaichamnankit, Kriengsak Lirdprapamongkol, Chantragan Srisomsap, Jisnuson Svasti, Voraratt Champattanachai
Pages: 1933-1942
Published online on: 05 August 2015

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Article

MicroRNA-338 inhibits migration and proliferation by targeting hypoxia-induced factor 1α in nasopharyngeal carcinoma Corrigendum in /10.3892/or.2022.8358

Ying Shan, Xingyu Li, Bo You, Si Shi, Qicheng Zhang, Yiwen You
Pages: 1943-1952
Published online on: 10 August 2015

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Article

Targeted delivery of doxorubicin to breast cancer cells by aptamer functionalized DOTAP/DOPE liposomes

Xingli Song, Yi Ren, Jing Zhang, Gang Wang, Xuedong Han, Wei Zheng, Linlin Zhen
Pages: 1953-1960
Published online on: 17 July 2015

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Article

Prediction of response to preoperative chemoradiotherapy and establishment of individualized therapy in advanced rectal cancer

Toshihiro Nakao, Takashi Iwata, Masanori Hotchi, Kozo Yoshikawa, Jun Higashijima, Masaaki Nishi, Chie Takasu, Shohei Eto, Hiroki Teraoku, Mitsuo Shimada
Pages: 1961-1967
Published online on: 10 August 2015

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Article

Inhibition of carbonic anhydrase IX (CA9) sensitizes renal cell carcinoma to ionizing radiation

Wilhelmina C.M. Duivenvoorden, Sarah N. Hopmans, Daniel Gallino, Thomas Farrell, Carrie Gerdes, Diana Glennie, Himu Lukka, Jehonathan H. Pinthus
Pages: 1968-1976
Published online on: 07 August 2015

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Article

Inhibition of sphingosine-1-phosphate phosphatase 1 promotes cancer cells migration in gastric cancer: Clinical implications Corrigendum in /10.3892/or.2018.6269

Xiang Y. Gao, Lin Li, Xiao H. Wang, Xian Z. Wen, Ke Ji, Lin Ye, Jun Cai, Wen G. Jiang, Jia F. Ji
Pages: 1977-1987
Published online on: 30 July 2015

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Article

MicroRNA-374a promotes esophageal cancer cell proliferation via Axin2 suppression

Yue Wang, Hua Xin, Zhifeng Han, Hongbing Sun, Nan Gao, Haixiang Yu
Pages: 1988-1994
Published online on: 07 August 2015

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Article

Dendritic cells combined with anti-GITR antibody produce antitumor effects in osteosarcoma

Masanori Kawano, Kazuhiro Tanaka, Ichiro Itonaga, Tatsuya Iwasaki, Masashi Miyazaki, Shinichi Ikeda, Hiroshi Tsumura
Pages: 1995-2001
Published online on: 29 July 2015

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Article

Mechanisms and in vitro effects of cepharanthine hydrochloride: Classification analysis of the drug-induced differentially-expressed genes of human nasopharyngeal carcinoma cells

Guanjun Liu, Dongmei Wu, Xinqiang Liang, Huifen Yue, Ying Cui
Pages: 2002-2010
Published online on: 10 August 2015

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Article

NOV inhibits proliferation while promoting apoptosis and migration in osteosarcoma cell lines through p38/MAPK and JNK/MAPK pathways

Juan Yao, Yaguang Weng, Shujuan Yan, Mengyi Hou, Hao Wang, Qiong Shi, Guowei Zuo
Pages: 2011-2021
Published online on: 24 July 2015

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Article

Fusion of cancer stem cells and mesenchymal stem cells contributes to glioma neovascularization

Chao Sun, Dongliang Zhao, Xingliang Dai, Jinsheng Chen, Xiaoci Rong, Haiyang Wang, Aidong Wang, Ming Li, Jun Dong, Qiang Huang, Qing Lan
Pages: 2022-2030
Published online on: 16 July 2015

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Article

Protective effect of neutralizing anti-IL-18α monoclonal antibody on a mouse model of acute graft-versus-host disease

Xiaocui Li, Cuiping Zhang, Wei Chen, Bin Pan, Fanyun Kong, Kuiyang Zheng, Renxian Tang, Lingyu Zeng
Pages: 2031-2039
Published online on: 05 August 2015

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Article

Aqueous extract of Psoralea corylifolia L. inhibits lipopolysaccharide-induced endothelial-mesenchymal transition via downregulation of the NF-κB-SNAIL signaling pathway

Bom Jung, Eun Hyang Jang, Darong Hong, In Hye Cho, Min-Ju Park, Jong-Ho Kim
Pages: 2040-2046
Published online on: 27 July 2015

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Article

Clinicopathological significance of N-cadherin and VEGF in advanced gastric cancer brain metastasis and the effects of metformin in preclinical models

Kyong-Hwa Jun, Jung Eun Lee, Se Hoon Kim, Ji-Han Jung, Hyun‑Joo Choi, Young Il Kim, Hyung-Min Chin, Seung-Ho Yang
Pages: 2047-2053
Published online on: 10 August 2015

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Article

MicroRNA-122 affects cell aggressiveness and apoptosis by targeting PKM2 in human hepatocellular carcinoma Corrigendum in /10.3892/or.2021.8073 Retraction in /10.3892/or.2023.8475

Qiuran Xu, Meiqi Zhang, Jianfeng Tu, Linxiao Pang, Wenwei Cai, Xin Liu
Pages: 2054-2064
Published online on: 05 August 2015

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Article

Valproic acid suppresses the self-renewal and proliferation of head and neck cancer stem cells

Sang Hyuk Lee, Hyo Jung Nam, Hyun Jung Kang, Tina L. Samuels, Nikki Johnston, Young Chang Lim
Pages: 2065-2071
Published online on: 23 July 2015

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Article

Gene expression profiling in myelodysplastic syndrome after SPARC overexpression associated with Ara-C

Qing Nian, Zhiqiang Zhang, Chunmei Wei, Xingyi Kuang, Xingyong Wang, Li Wang
Pages: 2072-2082
Published online on: 20 July 2015

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Article

MG132 enhances the radiosensitivity of lung cancer cells in vitro and in vivo

Wei Zhu, Jing Liu, Jihua Nie, Wenjiong Sheng, Han Cao, Wenhao Shen, Aijing Dong, Jundong Zhou, Yang Jiao, Shuyu Zhang, Jianping Cao
Pages: 2083-2089
Published online on: 04 August 2015

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Article

Hepatitis B virus X protein modifies invasion, proliferation and the inflammatory response in an HTR-8/SVneo cell model

Hong Cui, Qiu-Ling Li, Jing Chen, Quan Na, Cai-Xia Liu
Pages: 2090-2098
Published online on: 05 August 2015

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Article

Expression of immune checkpoint molecules of T cell immunoglobulin and mucin protein 3/galectin-9 for NK cell suppression in human gastrointestinal stromal tumors

Hideo Komita, Shigeo Koido, Kazumi Hayashi, Shin Kan, Masaki Ito, Yuko Kamata, Masafumi Suzuki, Sadamu Homma
Pages: 2099-2105
Published online on: 24 July 2015

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Article

Effect of Raf kinase inhibitor protein expression on malignant biological behavior and progression of colorectal cancer

Yun Wang, Ling-Yun Wang, Fen Feng, Yang Zhao, Ma-Yan Huang, Qiong Shao, Cui Chen, Hui Sheng, Dong-Liang Chen, Zhao-Lei Zeng, Rui-Hua Xu, Yu-Hong Li
Pages: 2106-2114
Published online on: 28 July 2015

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Article

Effect of DR4 promoter methylation on the TRAIL‑induced apoptosis in lung squamous carcinoma cell

Wenwu Wang, Xiaoyan Qi, Minghua Wu
Pages: 2115-2125
Published online on: 04 August 2015

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Article

Enrichment and characterization of cancer stem cells from a human non-small cell lung cancer cell line

Changhong Zhao, Sarra Setrerrahmane, Hanmei Xu
Pages: 2126-2132
Published online on: 30 July 2015

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Article

Simvastatin protects Sertoli cells against cisplatin cytotoxicity through enhanced gap junction intercellular communication

Lingzhi Wang, Jianxin Peng, Huansen Huang, Qin Wang, Meiling Yu, Liang Tao
Pages: 2133-2141
Published online on: 10 August 2015

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Article

Meloxicam combined with sorafenib synergistically inhibits tumor growth of human hepatocellular carcinoma cells via ER stress-related apoptosis

Jingtao Zhong, Peng Xiu, Xiaofeng Dong, Fuhai Wang, Honglong Wei, Xin Wang, Zongzhen Xu, Feng Liu, Tao Li, Yong Wang, Jie Li
Pages: 2142-2150
Published online on: 06 August 2015

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Article

A genetic polymorphism (rs17251221) in the calcium-sensing receptor is associated with ovarian cancer susceptibility

Shi Yan, Cunzhong Yuan, Qifeng Yang, Xiaoyan Li, Ning Yang, Xiaoyan Liu, Ruihua Dong, Xi Zhang, Zeng Yuan, Ning Zhang, Beihua Kong
Pages: 2151-2155
Published online on: 05 August 2015

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Article

Gentian violet inhibits MDA-MB-231 human breast cancer cell proliferation, and reverses the stimulation of osteoclastogenesis and suppression of osteoblast activity induced by cancer cells

Masayoshi Yamaguchi, Tatyana Vikulina, M. Neale Weitzmann
Pages: 2156-2162
Published online on: 10 August 2015

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MicroRNA-205 inhibits the proliferation and invasion of breast cancer by regulating AMOT expression

Haige Zhang, Qingxia Fan
Pages: 2163-2170
Published online on: 23 July 2015

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miR-138 suppresses the proliferation of oral squamous cell carcinoma cells by targeting Yes-associated protein 1

Ran Xu, Guang Zeng, Jing Gao, Yue Ren, Zhe Zhang, Qingna Zhang, Jinxiu Zhao, Hong Tao, Daxu Li
Pages: 2171-2178
Published online on: 23 July 2015

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HGF mediated upregulation of lipocalin 2 regulates MMP9 through nuclear factor-κB activation

Sung Ae Koh, Kyung Hee Lee
Pages: 2179-2187
Published online on: 10 August 2015

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Article

miR-519d-mediated downregulation of STAT3 suppresses breast cancer progression

Xin Deng, Yi Zhao, Baosheng Wang
Pages: 2188-2194
Published online on: 29 July 2015

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Article

MicroRNA-124 suppresses the migration and invasion of osteosarcoma cells via targeting ROR2-mediated non-canonical Wnt signaling Retraction in /10.3892/or.2021.8107

Can Zhang, Yihe Hu, Jun Wan, Hongbo He
Pages: 2195-2201
Published online on: 10 August 2015

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Article

miR-126 inhibits papillary thyroid carcinoma growth by targeting LRP6 Retraction in /10.3892/or.2021.8097

Qiang Wen, Jie Zhao, Lin Bai, Tongtong Wang, Haishan Zhang, Qingjie Ma
Pages: 2202-2210
Published online on: 31 July 2015

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Journal Cover
July-2026 Volume 56 Issue 1

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Impact Factor: 3.9

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

Advances in Kruppel‑like factor 5 as a transcription factor and its role in gynecological tumors (Review)

Shuqi Zhang, Ping Li, Lixia Zhu
Article Number: 139
Published online on: 28 May 2026

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Review Open Access

Ferroptosis in colorectal cancer: Molecular mechanisms and regulatory crosstalk with therapeutic prospects (Review)

Mingxing Wu, Mingrong Zhang
Article Number: 138
Published online on: 27 May 2026

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Correction Open Access

[Corrigendum] 17‑AAG synergizes with Belinostat to exhibit a negative effect on the proliferation and invasion of MDA‑MB‑231 breast cancer cells

Yu Zuo, Heng Xu, Zhifeng Chen, Fengmin Xiong, Bei Zhang, Kaixian Chen, Hualiang Jiang, Cheng Luo, Hao Zhang
Article Number: 137
Published online on: 27 May 2026

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Targeting lung cancer with tanshinones: Current mechanistic evidence and emerging opportunities (Review)

Zhengqi Guo, Xiaoci Li, Pengyu Suo, Zhanyu Lin, Ruixin Liu, Chenyu Chi
Article Number: 136
Published online on: 26 May 2026

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Immune network remodeling driven by ferroptosis: Bidirectional interaction mechanisms among multiple immune cells in the lung cancer immune microenvironment (Review)

Fei Qu, Jiale Tong, Weiwei Qian, Qian He
Article Number: 135
Published online on: 26 May 2026

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Correction Open Access

[Corrigendum] Rapamycin enhances the sensitivity of ER‑positive breast cancer cells to tamoxifen by upregulating p73 expression

Lei Zhu, Xiao-Xia Li, Liang Shi, Jing Wu, Jia-Yi Qian, Tian-Song Xia, Wen-Bin Zhou, Xi Sun, Xu-Jie Zhou, Ji-Fu Wei, Qiang Ding
Article Number: 134
Published online on: 20 May 2026

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Dual roles of lactylation modification in gastric cancer: Crosstalk between metabolic reprogramming and epigenetic regulation (Review)

Yuanbo Xu, Weili Wang, Yating Zhang, Yinqiu Fan, Wanying Dong, Jun Yang
Article Number: 133
Published online on: 20 May 2026

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Retraction Open Access

[Retracted] Hsp90 inhibitor 17‑AAG inhibits stem cell‑like properties and chemoresistance in osteosarcoma cells via the Hedgehog signaling pathway

Xiong Shu, Huiqi Liu, Rui Zhen, Yongsheng Jie, Lei Chen, Hui Qi, Chao Wang, Renxian Wang, Dafu Chen, Yuliang Ran
Article Number: 132
Published online on: 18 May 2026

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Article Open Access

Combination of ivermectin and metformin promotes autophagy in MCF‑7 cells by inhibiting phosphorylation of the PI3K/AKT/mTOR pathway

Huili Feng, Lixin He, Talha Umar, Haipeng Wang, Yanling Gao, Gongyi Chen, Panfeng Sun, Ling Yin, Wenbin Zhao, Huifang Lu, Ganzhen Deng, Changwei Qiu
Article Number: 131
Published online on: 14 May 2026

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Correction Open Access

[Corrigendum] ENO2 affects the EMT process of renal cell carcinoma and participates in the regulation of the immune micro­environment

Wei-Jie Chen, Wei Yang, Min Gong, Yi He, Da Xu, Jia-Xin Chen, Wen-Jin Chen, Wen-Yan Li, Yu-Qi Wang, Ke-Qin Dong, Xu Song, Xiu-Wu Pan, Xin-Gang Cui
Article Number: 130
Published online on: 13 May 2026

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SRRT promotes prostate cancer progression and serves as a prognostic biomarker through STAT3 pathway activation

Lingxiang Lu, Ke Wu, Zhenfan Wang, Ruoxi Yang, Kai Li, Shuai Guo, Fei Wang, Zheng Ma
Article Number: 129
Published online on: 13 May 2026

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Retraction Open Access

[Retracted] Hsp72 controls bortezomib‑induced HepG2 cell death via interaction with pro‑apoptotic factors 

Giuseppe Calvaruso, Michela Giuliano, Patrizia Portanova, Ornella Pellerito, Renza Vento, Giovanni Tesoriere
Article Number: 128
Published online on: 11 May 2026

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Effect of the miR‑26a/b‑5p‑STAT3‑YKL‑40 regulatory axis on proliferation, migration, and invasion of endometrial cancer cells

Xinzhao Sun, Shanshan Lin, Xueyan Zhong, Yanlu Luo, Jiahuang Yang, Jiangtao Fan
Article Number: 127
Published online on: 08 May 2026

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Cancer signaling networks in tumor progression and drug resistance: Crosstalk, adaptive reprogramming and therapeutic targeting (Review)

Hongyan Li, Shiyuan Song, Linlin Wang, Qiang Liu
Article Number: 126
Published online on: 08 May 2026

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A novel regulatory role of microRNA‑5590‑3p in hepatocellular carcinoma via the HOXB2/MYC axis

Bin Li, Lin Zhou
Article Number: 125
Published online on: 07 May 2026

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Retraction Open Access

[Retracted] SHIP1 is targeted by miR‑155 in acute myeloid leukemia

Hua Xue, Luo-Ming Hua, Ming Guo, Jian-Min Luo
Article Number: 124
Published online on: 05 May 2026

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Review Open Access

Chronic stress and cancer progression through neuro‑endocrine‑immune networks (Review)

Zhangxiang Zhu, Xiaohu Zhang, Jing Yan, Mingquan Wang, Yang Lv, Wuqiong Zhang, Hui Guo, Aimei Zheng
Article Number: 123
Published online on: 04 May 2026

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Retraction Open Access

[Retracted] PTEN enhances G2/M arrest in etoposide‑treated MCF‑7 cells through activation of the ATM pathway

Ruopeng Zhang, Li Zhu, Lirong Zhang, Anli Xu, Zhengwei Li, Yijuan Xu, Pei He, Maoqing Wu, Fengxiang Wei, Chenhong Wang
Article Number: 122
Published online on: 29 April 2026

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Journal Cover
August-2026 Volume 56 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

A fibroblast activation protein degrader enhances cisplatin sensitivity in non‑small cell lung cancer

Yong Zhou, Ranhua Li, Xiaobo Chen, Cheng Zhang, Yanan Bao, Yue Cui, Xinghe Tong, Ting Xia, Xudong Yang, Jiqing Yang, Xiaochuan Yin
Article Number: 145
Published online on: 10 June 2026

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Sterol regulatory element‑binding proteins: Master regulators of lipid metabolic reprogramming in cancer and emerging therapeutic targets (Review)

Qing Liu, Rui Wang, Zhenbo Li, Yihan Liu, Lei Wu, Yuqin Zhao, Jing Yang
Article Number: 144
Published online on: 04 June 2026

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Dual targeting of mitochondrial metabolism and Rho GTPase signaling to suppress cancer metastasis (Review)

Angelina Daher, Zahraa Assi, Amjad Kanaan, Ahmad Al Khatib, Mirvat El Sibai
Article Number: 143
Published online on: 03 June 2026

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Targeting colorectal cancer and T‑cell metabolism for the treatment of colorectal cancer (Review)

Qiangzong Yu, Pengbo Luan, Jingru Liang, Lixin Wang
Article Number: 142
Published online on: 02 June 2026

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Expression of Concern Open Access

[Expression of Concern] Antitumor activity of Notch‑1 inhibition in human colorectal carcinoma cells

Wangdi Liao, Guohua Li, Yu You, Hongping Wan, Qiong Wu, Chongwen Wang, Nonghua Lv
Article Number: 141
Published online on: 02 June 2026

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Article Open Access

Acylglycerol kinase contributes to cell proliferation by activating NF‑κB signaling pathway in pancreatic cancer

Kunkun Han, Qianyun Zhang, Shengnan Gao, Jigang Zhang, Xiao Mei, Fei Li, Xin Xu, Shu Li, Guodong Chen
Article Number: 140
Published online on: 29 May 2026

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