Journal Articles
Review
The complex liaison between cachexia and tumor burden (Review)
Andrea De Lerma Barbaro
Pages: 1635-1649 Published online on: 31 July 2015
Article
NOTCH2 signaling confers immature morphology and aggressiveness in human hepatocellular carcinoma cells
Yoshihiro Hayashi, Makoto Osanai, Gang-Hong Lee
Pages: 1650-1658 Published online on: 04 August 2015
Article
Selective induction of apoptosis in human gastric cancer cells by Lactobacillus kefiri (PFT), a novel kefir product
Mamdooh Ghoneum, Nouran Felo
Pages: 1659-1666 Published online on: 06 August 2015
Article
Impact of reduced levels of APE1 transcripts on the survival of patients with urothelial carcinoma of the bladder
Mariana Chantre-Justino, Gilda Alves, Constança Britto, Angélica Cardoso, Luciano Scherrer, Aline dos Santos Moreira, Raul Quirino, Antonio Ornellas, Alvaro Leitão, Claudia Lage
Pages: 1667-1674 Published online on: 24 July 2015
Article
Differential crosstalk between the AMPK and PI3K/Akt pathways in breast cancer cells of differing genotypes: Leptin inhibits the effectiveness of AMPK activation
Omar S. El-Masry, Kaltoom Al-Sakkaf, Barry L. Brown, Pauline R.M. Dobson
Pages: 1675-1680 Published online on: 11 August 2015
Article
HOXD10 acts as a tumor-suppressive factor via inhibition of the RHOC/AKT/MAPK pathway in human cholangiocellular carcinoma
Haixia Yang, Jiupeng Zhou, Jianqiang Mi, Ke Ma, Yangwei Fan, Jing Ning, Chuying Wang, Xin Wei, Huadong Zhao, Enxiao Li
Pages: 1681-1691 Published online on: 10 August 2015
Article
Nutlin-3 sensitizes nasopharyngeal carcinoma cells to cisplatin-induced cytotoxicity
Yee-Lin Voon, Munirah Ahmad, Pooi-Fong Wong, Roslina Husaini, Wayne Tiong-Weng Ng, Chee-Onn Leong, David Philip Lane, Alan Soo-Beng Khoo
Pages: 1692-1700 Published online on: 05 August 2015
Article
Acquirement of DNA copy number variations in non‑small cell lung cancer metastasis to the brain
Fang Li, Libo Sun, Sixun Zhang
Pages: 1701-1707 Published online on: 10 August 2015
Article
The novel mTOR inhibitor Torin-2 induces autophagy and downregulates the expression of UHRF1 to suppress hepatocarcinoma cell growth
Congren Wang, Xuejin Wang, Zijian Su, Hongjiang Fei, Xiaoyu Liu, Qunxiong Pan
Pages: 1708-1716 Published online on: 23 July 2015
Article
Significance of expression of glucagon-like peptide 1 receptor in pancreatic cancer
Ana Ines Cases, Takao Ohtsuka, Hideyo Kimura, Biao Zheng, Koji Shindo, Yoshinao Oda, Kazuhiro Mizumoto, Masafumi Nakamura, Masao Tanaka
Pages: 1717-1725 Published online on: 20 July 2015
Article
Inhibition of NADPH oxidase 4 induces apoptosis in malignant mesothelioma: Role of reactive oxygen species
Motoya Tanaka, Yuji Miura, Hiroki Numanami, Sivasundaram Karnan, Akinobu Ota, Hiroyuki Konishi, Yoshitaka Hosokawa, Masayuki Hanyuda
Pages: 1726-1732 Published online on: 27 July 2015
Article
Dual effects of human adipose tissue-derived mesenchymal stem cells in human lung adenocarcinoma A549 xenografts and colorectal adenocarcinoma HT-29 xenografts in mice
Jung Joo Rhyu, Jun-Won Yun, Euna Kwon, Jeong-Hwan Che, Byeong-Cheol Kang
Pages: 1733-1744 Published online on: 07 August 2015
Article
Subpath analysis of each subtype of head and neck cancer based on the regulatory relationship between miRNAs and biological pathways
Fengwei An, Zhiqiang Zhang, Ming Xia, Lijun Xing
Pages: 1745-1754 Published online on: 24 July 2015
Article
12-Deoxyphorbol 13-palmitate inhibits the expression of VEGF and HIF-1α in MCF-7 cells by blocking the PI3K/Akt/mTOR signaling pathway
Ying Yang, Huan Cong, Cuicui Han, Liling Yue, Haiying Dong, Jicheng Liu
Pages: 1755-1760 Published online on: 31 July 2015
Article
Galectin-9 suppresses cholangiocarcinoma cell proliferation by inducing apoptosis but not cell cycle arrest
Kiyoyuki Kobayashi, Asahiro Morishita, Hisakazu Iwama, Koji Fujita, Ryoichi Okura, Shintaro Fujihara, Takuma Yamashita, Takayuki Fujimori, Kiyohito Kato, Hideki Kamada, Toshiro Niki, Mitsuomi Hirashima, Keiichi Okano, Yasuyuki Suzuki, Tsutomu Masaki
Pages: 1761-1770 Published online on: 10 August 2015
Article
microRNA-22 downregulation of galectin-9 influences lymphocyte apoptosis and tumor cell proliferation in liver cancer
Qianqian Yang, Weichao Jiang, Chunbo Zhuang, Zhi Geng, Chen Hou, Da Huang, Lihua Hu, Xiaobei Wang
Pages: 1771-1778 Published online on: 31 July 2015
Article
Expression profile analysis of microRNAs and downregulated miR-486-5p and miR-30a-5p in non-small cell lung cancer
Jianjie Zhu, Yuanyuan Zeng, Chun Xu, Hualong Qin, Zhe Lei, Dan Shen, Zeyi Liu, Jian-An Huang
Pages: 1779-1786 Published online on: 21 July 2015
Article
Twist induces epithelial-mesenchymal transition in cervical carcinogenesis by regulating the TGF-β/Smad3 signaling pathway
Qiong Fan, Mei-Ting Qiu, Zhu Zhu, Jin-Hua Zhou, Limo Chen, Ye Zhou, Wei Gu, Li‑Hua Wang, Zhu-Nan Li, Ying Xu, Wei-Wei Cheng, Dan Wu, Wei Bao
Pages: 1787-1794 Published online on: 22 July 2015
Article
Enhanced therapeutic effects against murine colon carcinoma induced by a Colon 26/Ag85A-CD226 tumor cell vaccine
Yan Li, Fangli Yang, Lixuan Sang, Junfeng Zhu, Xue Han, Fengping Shan, Shengjun Li, Jingbo Zhai, Danan Wang, Changlong Lu, Xun Sun
Pages: 1795-1804 Published online on: 20 July 2015
Article
Inhibiting GLUT-1 expression and PI3K/Akt signaling using apigenin improves the radiosensitivity of laryngeal carcinoma in vivo
Yang‑Yang Bao, Shui‑Hong Zhou, Zhong‑Jie Lu, Jun Fan, Ya‑Ping Huang
Pages: 1805-1814 Published online on: 28 July 2015
Article
Expression of cortactin in human gliomas and its effect on migration and invasion of glioma cells
Leilei Wang, Kai Zhao, Bingcheng Ren, Meng Zhu, Chen Zhang, Pengfei Zhao, Hua Zhou, Lei Chen, Shenping Yu, Xuejun Yang
Pages: 1815-1824 Published online on: 28 July 2015
Article
Targeting effect of PEGylated liposomes modified with the Arg-Gly-Asp sequence on gastric cancer
Jie Ding, Min Feng, Feng Wang, Hao Wang, Wenxian Guan
Pages: 1825-1834 Published online on: 22 July 2015
Article
Effect of Rab23 on the proliferation and apoptosis in breast cancer
Yali Liu, Chao Zeng, Nandi Bao, Jie Zhao, Yuzhen Hu, Chengxin Li, Sumin Chi
Pages: 1835-1844 Published online on: 24 July 2015
Article
MicroRNA-144 affects radiotherapy sensitivity by promoting proliferation, migration and invasion of breast cancer cells
Lei Yu, Yanming Yang, Jiguang Hou, Chengwei Zhai, Yunhao Song, Zhiliang Zhang, Ling Qiu, Xiaojing Jia
Pages: 1845-1852 Published online on: 05 August 2015
Article
Curcumin alters gene expression-associated DNA damage, cell cycle, cell survival and cell migration and invasion in NCI-H460 human lung cancer cells in vitro
I-Tsang Chiang, Wei-Shu Wang, Hsin-Chung Liu, Su-Tso Yang, Nou-Ying Tang, Jing-Gung Chung
Pages: 1853-1874 Published online on: 29 July 2015
Article
Novel quinazoline derivatives exhibit antitumor activity by inhibiting JAK2/STAT3
Haishi Qiao, Dan Zhao, Hengfei Shi, Ke Ren, Jianxin Li, Erguang Li
Pages: 1875-1882 Published online on: 21 July 2015
Article
RRM1, TUBB3, TOP2A, CYP19A1, CYP2D6: Difference between mRNA and protein expression in predicting prognosis of breast cancer patients
Ying-Chun Xu, Feng-Chun Zhang, Jun-Jian Li, Jia-Qi Dai, Qiang Liu, Lei Tang, Yue Ma, Qi Xu, Xiao-Lin Lin, Hong-Bin Fan, Hong-Xia Wang
Pages: 1883-1894 Published online on: 07 August 2015
Article
Inhibitory effects of 3-bromopyruvate in human nasopharyngeal carcinoma cells
Xue Zou, Mengxiao Zhang, Yiming Sun, Surong Zhao, Yingmei Wei, Xudong Zhang, Chenchen Jiang, Hao Liu
Pages: 1895-1904 Published online on: 23 July 2015
Article
Never in mitosis gene A-related kinase 6 and aurora kinase A: New gene biomarkers in the conversion from ulcerative colitis to colorectal cancer
Emre Gerçeker, Seda Orenay Boyacıoglu, Elmas Kasap, Ahmed Baykan, Hakan Yuceyar, Hatice Yıldırım, Semin Ayhan, Ender Ellidokuz, Mehmet Korkmaz
Pages: 1905-1914 Published online on: 10 August 2015
Article
Bone marrow-derived mesenchymal stem cells co‑expressing interleukin-18 and interferon-β exhibit potent antitumor effect against intracranial glioma in rats
Gang Xu, Yanwu Guo, Zhiyuan Seng, Gang Cui, Jianqiang Qu
Pages: 1915-1922 Published online on: 05 August 2015
Article
miR-219-5p plays a tumor suppressive role in colon cancer by targeting oncogene Sall4
Ji Cheng, Rui Deng, Peng Zhang, Chuanqing Wu, Ke Wu, Liang Shi, Xinghua Liu, Jie Bai, Meizhou Deng, Xiaoming Shuai, Jinbo Gao, Guobin Wang, Kaixiong Tao
Pages: 1923-1932 Published online on: 04 August 2015
Article
Alteration of O-GlcNAcylation affects serine phosphorylation and regulates gene expression and activity of pyruvate kinase M2 in colorectal cancer cells
Parunya Chaiyawat, Daranee Chokchaichamnankit, Kriengsak Lirdprapamongkol, Chantragan Srisomsap, Jisnuson Svasti, Voraratt Champattanachai
Pages: 1933-1942 Published online on: 05 August 2015
Article
MicroRNA-338 inhibits migration and proliferation by targeting hypoxia-induced factor 1α in nasopharyngeal carcinoma Corrigendum in /10.3892/or.2022.8358
Ying Shan, Xingyu Li, Bo You, Si Shi, Qicheng Zhang, Yiwen You
Pages: 1943-1952 Published online on: 10 August 2015
Article
Targeted delivery of doxorubicin to breast cancer cells by aptamer functionalized DOTAP/DOPE liposomes
Xingli Song, Yi Ren, Jing Zhang, Gang Wang, Xuedong Han, Wei Zheng, Linlin Zhen
Pages: 1953-1960 Published online on: 17 July 2015
Article
Prediction of response to preoperative chemoradiotherapy and establishment of individualized therapy in advanced rectal cancer
Toshihiro Nakao, Takashi Iwata, Masanori Hotchi, Kozo Yoshikawa, Jun Higashijima, Masaaki Nishi, Chie Takasu, Shohei Eto, Hiroki Teraoku, Mitsuo Shimada
Pages: 1961-1967 Published online on: 10 August 2015
Article
Inhibition of carbonic anhydrase IX (CA9) sensitizes renal cell carcinoma to ionizing radiation
Wilhelmina C.M. Duivenvoorden, Sarah N. Hopmans, Daniel Gallino, Thomas Farrell, Carrie Gerdes, Diana Glennie, Himu Lukka, Jehonathan H. Pinthus
Pages: 1968-1976 Published online on: 07 August 2015
Article
Inhibition of sphingosine-1-phosphate phosphatase 1 promotes cancer cells migration in gastric cancer: Clinical implications Corrigendum in /10.3892/or.2018.6269
Xiang Y. Gao, Lin Li, Xiao H. Wang, Xian Z. Wen, Ke Ji, Lin Ye, Jun Cai, Wen G. Jiang, Jia F. Ji
Pages: 1977-1987 Published online on: 30 July 2015
Article
MicroRNA-374a promotes esophageal cancer cell proliferation via Axin2 suppression
Yue Wang, Hua Xin, Zhifeng Han, Hongbing Sun, Nan Gao, Haixiang Yu
Pages: 1988-1994 Published online on: 07 August 2015
Article
Dendritic cells combined with anti-GITR antibody produce antitumor effects in osteosarcoma
Masanori Kawano, Kazuhiro Tanaka, Ichiro Itonaga, Tatsuya Iwasaki, Masashi Miyazaki, Shinichi Ikeda, Hiroshi Tsumura
Pages: 1995-2001 Published online on: 29 July 2015
Article
Mechanisms and in vitro effects of cepharanthine hydrochloride: Classification analysis of the drug-induced differentially-expressed genes of human nasopharyngeal carcinoma cells
Guanjun Liu, Dongmei Wu, Xinqiang Liang, Huifen Yue, Ying Cui
Pages: 2002-2010 Published online on: 10 August 2015
Article
NOV inhibits proliferation while promoting apoptosis and migration in osteosarcoma cell lines through p38/MAPK and JNK/MAPK pathways
Juan Yao, Yaguang Weng, Shujuan Yan, Mengyi Hou, Hao Wang, Qiong Shi, Guowei Zuo
Pages: 2011-2021 Published online on: 24 July 2015
Article
Fusion of cancer stem cells and mesenchymal stem cells contributes to glioma neovascularization
Chao Sun, Dongliang Zhao, Xingliang Dai, Jinsheng Chen, Xiaoci Rong, Haiyang Wang, Aidong Wang, Ming Li, Jun Dong, Qiang Huang, Qing Lan
Pages: 2022-2030 Published online on: 16 July 2015
Article
Protective effect of neutralizing anti-IL-18α monoclonal antibody on a mouse model of acute graft-versus-host disease
Xiaocui Li, Cuiping Zhang, Wei Chen, Bin Pan, Fanyun Kong, Kuiyang Zheng, Renxian Tang, Lingyu Zeng
Pages: 2031-2039 Published online on: 05 August 2015
Article
Aqueous extract of Psoralea corylifolia L. inhibits lipopolysaccharide-induced endothelial-mesenchymal transition via downregulation of the NF-κB-SNAIL signaling pathway
Bom Jung, Eun Hyang Jang, Darong Hong, In Hye Cho, Min-Ju Park, Jong-Ho Kim
Pages: 2040-2046 Published online on: 27 July 2015
Article
Clinicopathological significance of N-cadherin and VEGF in advanced gastric cancer brain metastasis and the effects of metformin in preclinical models
Kyong-Hwa Jun, Jung Eun Lee, Se Hoon Kim, Ji-Han Jung, Hyun‑Joo Choi, Young Il Kim, Hyung-Min Chin, Seung-Ho Yang
Pages: 2047-2053 Published online on: 10 August 2015
Article
MicroRNA-122 affects cell aggressiveness and apoptosis by targeting PKM2 in human hepatocellular carcinoma Corrigendum in /10.3892/or.2021.8073 Retraction in /10.3892/or.2023.8475
Qiuran Xu, Meiqi Zhang, Jianfeng Tu, Linxiao Pang, Wenwei Cai, Xin Liu
Pages: 2054-2064 Published online on: 05 August 2015
Article
Valproic acid suppresses the self-renewal and proliferation of head and neck cancer stem cells
Sang Hyuk Lee, Hyo Jung Nam, Hyun Jung Kang, Tina L. Samuels, Nikki Johnston, Young Chang Lim
Pages: 2065-2071 Published online on: 23 July 2015
Article
Gene expression profiling in myelodysplastic syndrome after SPARC overexpression associated with Ara-C
Qing Nian, Zhiqiang Zhang, Chunmei Wei, Xingyi Kuang, Xingyong Wang, Li Wang
Pages: 2072-2082 Published online on: 20 July 2015
Article
MG132 enhances the radiosensitivity of lung cancer cells in vitro and in vivo
Wei Zhu, Jing Liu, Jihua Nie, Wenjiong Sheng, Han Cao, Wenhao Shen, Aijing Dong, Jundong Zhou, Yang Jiao, Shuyu Zhang, Jianping Cao
Pages: 2083-2089 Published online on: 04 August 2015
Article
Hepatitis B virus X protein modifies invasion, proliferation and the inflammatory response in an HTR-8/SVneo cell model
Hong Cui, Qiu-Ling Li, Jing Chen, Quan Na, Cai-Xia Liu
Pages: 2090-2098 Published online on: 05 August 2015
Article
Expression of immune checkpoint molecules of T cell immunoglobulin and mucin protein 3/galectin-9 for NK cell suppression in human gastrointestinal stromal tumors
Hideo Komita, Shigeo Koido, Kazumi Hayashi, Shin Kan, Masaki Ito, Yuko Kamata, Masafumi Suzuki, Sadamu Homma
Pages: 2099-2105 Published online on: 24 July 2015
Article
Effect of Raf kinase inhibitor protein expression on malignant biological behavior and progression of colorectal cancer
Yun Wang, Ling-Yun Wang, Fen Feng, Yang Zhao, Ma-Yan Huang, Qiong Shao, Cui Chen, Hui Sheng, Dong-Liang Chen, Zhao-Lei Zeng, Rui-Hua Xu, Yu-Hong Li
Pages: 2106-2114 Published online on: 28 July 2015
Article
Effect of DR4 promoter methylation on the TRAIL‑induced apoptosis in lung squamous carcinoma cell
Wenwu Wang, Xiaoyan Qi, Minghua Wu
Pages: 2115-2125 Published online on: 04 August 2015
Article
Enrichment and characterization of cancer stem cells from a human non-small cell lung cancer cell line
Changhong Zhao, Sarra Setrerrahmane, Hanmei Xu
Pages: 2126-2132 Published online on: 30 July 2015
Article
Simvastatin protects Sertoli cells against cisplatin cytotoxicity through enhanced gap junction intercellular communication
Lingzhi Wang, Jianxin Peng, Huansen Huang, Qin Wang, Meiling Yu, Liang Tao
Pages: 2133-2141 Published online on: 10 August 2015
Article
Meloxicam combined with sorafenib synergistically inhibits tumor growth of human hepatocellular carcinoma cells via ER stress-related apoptosis
Jingtao Zhong, Peng Xiu, Xiaofeng Dong, Fuhai Wang, Honglong Wei, Xin Wang, Zongzhen Xu, Feng Liu, Tao Li, Yong Wang, Jie Li
Pages: 2142-2150 Published online on: 06 August 2015
Article
A genetic polymorphism (rs17251221) in the calcium-sensing receptor is associated with ovarian cancer susceptibility
Shi Yan, Cunzhong Yuan, Qifeng Yang, Xiaoyan Li, Ning Yang, Xiaoyan Liu, Ruihua Dong, Xi Zhang, Zeng Yuan, Ning Zhang, Beihua Kong
Pages: 2151-2155 Published online on: 05 August 2015
Article
Gentian violet inhibits MDA-MB-231 human breast cancer cell proliferation, and reverses the stimulation of osteoclastogenesis and suppression of osteoblast activity induced by cancer cells
Masayoshi Yamaguchi, Tatyana Vikulina, M. Neale Weitzmann
Pages: 2156-2162 Published online on: 10 August 2015
Article
MicroRNA-205 inhibits the proliferation and invasion of breast cancer by regulating AMOT expression
Haige Zhang, Qingxia Fan
Pages: 2163-2170 Published online on: 23 July 2015
Article
miR-138 suppresses the proliferation of oral squamous cell carcinoma cells by targeting Yes-associated protein 1
Ran Xu, Guang Zeng, Jing Gao, Yue Ren, Zhe Zhang, Qingna Zhang, Jinxiu Zhao, Hong Tao, Daxu Li
Pages: 2171-2178 Published online on: 23 July 2015
Article
HGF mediated upregulation of lipocalin 2 regulates MMP9 through nuclear factor-κB activation
Sung Ae Koh, Kyung Hee Lee
Pages: 2179-2187 Published online on: 10 August 2015
Article
miR-519d-mediated downregulation of STAT3 suppresses breast cancer progression
Xin Deng, Yi Zhao, Baosheng Wang
Pages: 2188-2194 Published online on: 29 July 2015
Article
MicroRNA-124 suppresses the migration and invasion of osteosarcoma cells via targeting ROR2-mediated non-canonical Wnt signaling Retraction in /10.3892/or.2021.8107
Can Zhang, Yihe Hu, Jun Wan, Hongbo He
Pages: 2195-2201 Published online on: 10 August 2015
Article