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Experimental and Therapeutic Medicine
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
June 2012 Volume 3 Issue 6

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Impact Factor: 2.3

Article Open Access

Prunella vulgaris aqueous extract attenuates IL-1β-induced apoptosis and NF-κB activation in INS-1 cells

Huiping Wu, Ming Gao, Tuanzhu Ha, Jim Kelley, Ada Young, Kevin Breuel
Pages: 919-924
Published online on: 23 March 2012

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Article Open Access

Correlation between efficacy of PSK postoperative adjuvant immunochemotherapy for gastric cancer and expression of MHC class I

Gentaro Ito, Hiroaki Tanaka, Masaichi Ohira, Mami Yoshii, Kazuya Muguruma, Naoshi Kubo, Masakazu Yashiro, Nobuya Yamada, Kiyoshi Maeda, Tetsuji Sawada, Kosei Hirakawa
Pages: 925-930
Published online on: 02 April 2012

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Article Open Access

Membranous and cytoplasmic expression of epidermal growth factor receptor in metastatic pancreatic ductal adenocarcinoma

Takahiro Einama, Shigeto Ueda, Hitoshi Tsuda, Kazuhiro Ogasawara, Kazuo Hatsuse, Osamu Matsubara, Satoru Todo, Junji Yamamoto
Pages: 931-936
Published online on: 15 March 2012

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Article Open Access

Impact of increased erythropoietin receptor expression and elevated serum erythropoietin levels on clinicopathological features and prognosis in renal cell carcinoma

Keiichi Ito, Hidehiko Yoshii, Takako Asano, Akio Horiguchi, Makoto Sumitomo, Masamichi Hayakawa, Tomohiko Asano
Pages: 937-944
Published online on: 13 March 2012

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Article Open Access

Metabonomic signature analysis of cervical carcinoma and precancerous lesions in women by 1H NMR spectroscopy

Ayshamgul Hasim, Mayinuer Ali, Batur Mamtimin, Jun‑Qi  Ma, Qiao-Zhi Li, Abulizi Abudula
Pages: 945-951
Published online on: 12 March 2012

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Article

Intratumoral Wnt2B expression affects tumor proliferation and survival in malignant pleural mesothelioma patients

Masashi Kobayashi, Cheng-Long Huang, Makoto Sonobe, Ryutaro Kikuchi, Masashi Ishikawa, Jiro Kitamura, Ryo Miyahara, Toshi Menju, Shotaro Iwakiri, Kazumi Itoi, Ryoji Yasumizu, Hiroshi Date
Pages: 952-958
Published online on: 12 March 2012

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Article

Genotoxic therapy stimulates error-prone DNA repair in dormant hepatocellular cancer stem cells

Shimpei Nishikawa, Hideshi Ishii, Naotsugu Haraguchi, Yoshihiro Kano, Takahito Fukusumi, Katsuya Ohta, Miyuki Ozaki, Daisuke Sakai, Taroh Satoh, Hiroaki Nagano, Yuichiro Doki, Masaki Mori
Pages: 959-962
Published online on: 22 March 2012

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Article

Parathyroid hormone-related protein expression, in combination with nodal status, predicts bone metastasis and prognosis of breast cancer patients

Keiichi Takagaki, Tsutomu Takashima, Naoyoshi Onoda, Kenji Tezuka, Eiji Noda, Hidemi Kawajiri, Tetsuro Ishikawa, Kosei Hirakawa
Pages: 963-968
Published online on: 21 March 2012

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Article

Post-training consumption of wheat gluten hydrolysate suppresses the delayed onset of muscle injury in soccer players

Kazuhiro Aoki, Yoshimitsu Kohmura, Yoshio Suzuki, Natsue Koikawa, Masafumi Yoshimura, Yukihiro Aoba, Norifumi Fukushi, Keishoku Sakuraba, Isao Nagaoka, Keisuke Sawaki
Pages: 969-972
Published online on: 03 April 2012

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Article

Co-expression of CXCR4 and CD133 proteins is associated with poor prognosis in stage II-III colon cancer patients

Nian-Hua Zhang, Jie Li, Yin Li, Xin-Tao Zhang, Wen-Ting  Liao, Jun-Yi Zhang, Rong Li, Rong-Cheng Luo
Pages: 973-982
Published online on: 27 March 2012

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Article

Significance of survivin expression: Prognostic value and survival in stage III non-small cell lung cancer

Meng Wang, Bao-Gang Liu, Zhao-Yang Yang, Xuan Hong, Gong-Yan Chen
Pages: 983-988
Published online on: 12 March 2012

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Article

Endothelial cell protein C receptor gene 6936A/G polymorphism is associated with venous thromboembolism

Guancheng Yin, Xing Jin, Hanxin Ming, Xiao Zheng, Deqing Zhang
Pages: 989-992
Published online on: 12 March 2012

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Article

Prognostic value of nuclear maspin expression for adjuvant 5-fluorouracil-based chemotherapy in advanced gastric cancer

Ke-Feng Lei, Bing-Ya Liu, Xiao-Long Jin, Yan Guo, Min Ye, Zheng-Gang Zhu
Pages: 993-998
Published online on: 30 March 2012

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Article

Feasibility and effect of ultrasound microbubble-mediated wild-type p53 gene transfection of HeLa cells

Wen-Juan Chen, Zheng-Ai Xiong, Yan Tang, Pei-Ting Dong, Pan Li, Zhi-Gang Wang
Pages: 999-1004
Published online on: 27 March 2012

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Article

Screening and identification of serum proteomic biomarkers for gastric adenocarcinoma

Chibo Liu, Chunqin Pan, Yong Liang
Pages: 1005-1009
Published online on: 14 March 2012

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Article

Survivin expression in human lung cancer and the influence of its downregulation on the biological behavior of human lung cancer cells

Xiang-Qi Chen, Sheng Yang, Ming-Qiang Kang, Zhi-Ying Li, Hui-Shan Lu, Ting-Yan Lin
Pages: 1010-1014
Published online on: 23 March 2012

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Case Report

Hyalinizing trabecular tumor of the thyroid: Case report and review of the literature

Jing Li, Guang-Zhi Yang, Lan-Xiang Gao, Wen-Xiu Yan, Hua Jin, Lin Li
Pages: 1015-1017
Published online on: 28 March 2012

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Article

Continuous administration of recombinant human endostatin (Endostar): A pre-clinical safety study

Ruofan Huang, Qiong Zhan, Xinli Zhou, Zhaohui Chu, Jingwei Jiang, Xiaohua Liang
Pages: 1018-1022
Published online on: 30 March 2012

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Case Report

Syphilis manifesting as a nasopharyngeal carcinoma with cervical lymphadenopathy: A case report

Xinbin Pan, Xiaodong Zhu, Qingdi Quentin Li
Pages: 1023-1025
Published online on: 02 April 2012

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Article

Expression of p14ARF, p15INK4b, p16INK4a and skp2 increases during esophageal squamous cell cancer progression

Peng Bai, Xue Xiao, Juan Zou, Lin Cui, Tri M. Bui Nguyen, Jinsong Liu, Jianguo Xiao, Bin Chang, Jin Wu, He Wang
Pages: 1026-1032
Published online on: 22 March 2012

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Article

TAT-Apoptin induces apoptosis in the human bladder cancer EJ cell line and regulates Bax, Bcl-2, caspase-3 and survivin expression

Jun Li, Haifeng Wang, Zhen Ma, Wenxing Fan, Yanfeng  Li, Bingbing Han, Zhijia Zhang, Jiansong Wang
Pages: 1033-1038
Published online on: 21 March 2012

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Article

microRNA expression pattern and its alteration following celecoxib intervention in human colorectal cancer

Wei Chang Chen, Mao Song Lin, Yu Lan Ye, Heng Jun Gao, Zhen Yun Song, Xiao Ying Shen
Pages: 1039-1048
Published online on: 30 March 2012

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Article

Synergistic impact of Lactobacillus fermentum, Lactobacillus plantarum and vincristine on 1,2-dimethylhydrazine-induced colorectal carcinogenesis in mice

Asha Asha, Devaraja Gayathri
Pages: 1049-1054
Published online on: 02 April 2012

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Article

Comparative serum proteomic analysis involving liver organ-specific metastasis-associated proteins of nasopharyngeal carcinoma

Changchuan Pan, Yalan Tao, Ming Zhao, Wang Li, Zilin Huang, Jing Gao, Yanhen Wu, Jingrui Yu, Peihong Wu, Yunfei Xia, Jin Lu
Pages: 1055-1061
Published online on: 23 March 2012

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Article

Effect of healthcare insurance policy on the quality of life of chronic hepatitis C patients receiving interferon α-2a plus ribavirin therapy

Jing Liu, Chao-Shuang Lin, Wei-Qiang Gan, Yu-Bao Zheng, Zhe-Bin Wu, Zhi-Xin Zhao, Zhi-Liang Gao
Pages: 1062-1066
Published online on: 16 March 2012

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Article

Methylation of the RASSF1A and RARβ genes as a candidate biomarker for lung cancer

Wen Li, Jing Deng, Pei Jiang, Xiaoxi Zeng, Shunqin Hu, Jianxin Tang
Pages: 1067-1071
Published online on: 15 March 2012

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Article

Diagnostic accuracy of vascular endothelial growth factor for malignant pleural effusion: A meta-analysis

Yong-Chun Shen, Meng-Qi Liu, Chun Wan, Lei Chen, Tao Wang, Fu-Qiang Wen
Pages: 1072-1076
Published online on: 14 March 2012

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Article

Downregulation of phosphatase of regenerating liver-3 is involved in the inhibition of proliferation and apoptosis induced by emodin in the SGC-7901 human gastric carcinoma cell line

Zhen-Hua Sun, Ping Bu
Pages: 1077-1081
Published online on: 15 March 2012

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Article

The TNF-α -308G/A polymorphism is associated with migraine risk: A meta-analysis

Lian Gu, Yan Yan, Jianxiong Long, Li Su, Yanling Hu, Qing Chen, Juanjuan Xie, Guangliang Wu
Pages: 1082-1086
Published online on: 30 March 2012

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Article

Expression and subcellular localization of menin in human cancer cells

Feng Ren, Hong-Wei Xu, Yu Hu, Shuang-Hong Yan, Feng Wang, Bao-Wei Su, Qi Zhao
Pages: 1087-1091
Published online on: 29 March 2012

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Article

Autoantibodies against the signal peptide domain of Muc1 in patients with multiple myeloma: Implications for disease diagnosis and prognosis

Riva Kovjazin, Anna Dubnik, Galit Horn, Nechama I. Smorodinsky, Izhar Hardan, Michael Yechiel Shapira, Lior Carmon
Pages: 1092-1098
Published online on: 03 April 2012

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Journal Cover
May-2026 Volume 31 Issue 5

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Impact Factor: 2.3

Review Open Access

FCER1G: A multifunctional regulator in the immune microenvironment (Review)

Yuyu Zhang, Jinglan Wang, Wenting He, Tao Liu
Article Number: 146
Published online on: 26 March 2026

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Article Open Access

A nomogram for predicting recurrence‑free survival in patients with high‑risk GIST receiving adjuvant imatinib: A nationwide registry study

Chun-Nan Yeh, Yan-Shen Shan, Ching-Yao Yang, Chin-Fu Hsiao, Chung-Hsin Tsai, Chuan-Cheng Wang, Ming-Tsan Lin, Chun-Fu Ting, De-Chuan Chan, Te-Hung Chen, Chueh-Chuan Yen, Yen-Yang Chen, Hsuan-Yu Lin, Ta-Sen Yeh, Ching-Liang Ho, Tze-Yu Shieh, Li-Yaun Bai, Jun-Te Hsu, I-Shu Chen, Li-Tzong Chen, Hui-Jen Tsai, The Taiwan Cooperative Oncology Group Gist Study Group
Article Number: 145
Published online on: 24 March 2026

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Retraction Open Access

[Retracted] MicroRNA‑18a‑5p represses scar fibroblast proliferation and extracellular matrix deposition through regulating Smad2 expression

Tianshi Li, Yiguang Wu, Dandan Liu, Lida Zhuang
Article Number: 144
Published online on: 23 March 2026

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Article

Risk factors for severe retinopathy of prematurity: A retrospective case‑control study

Qingmin Ma, Xi Lv, Jiangya Wang, Kejun Li, Wenwen Τang
Article Number: 143
Published online on: 20 March 2026

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Article Open Access

Atorvastatin augments collateral formation and functional recovery after indirect revascularization in adult ischemic moyamoya disease: A randomized trial

Dawei Wang, Jingya Dai, Shumei Li, Yaping Liu, Xiaofeng Xing, Lei Huang, Qijun Pang
Article Number: 142
Published online on: 19 March 2026

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Article Open Access

Maresin 1 activates autophagy through SIRT1/PPAR‑γ signaling to mitigate high glucose‑induced pyroptosis in human retinal pigment epithelial cells

Jun Zhang, Ding Zhao, Yuanqing Zhang, Haoxiang Sun, Zhipeng Yan, Haiyan Sun
Article Number: 141
Published online on: 19 March 2026

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Review Open Access

Advances in new ultrasound technologies in targeted prostate biopsy (Review)

Tingting Jin, Liying Wang, Shusen Zheng
Article Number: 140
Published online on: 19 March 2026

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Review Open Access

Immune cross talk and therapeutic advances in lactate metabolism in the tumor microenvironment (Review)

Min Liu, Kui Su
Article Number: 139
Published online on: 19 March 2026

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Article Open Access

Immunohistochemical evaluation of gastric‑type markers in primary extramammary Paget disease: Differential MUC5AC expression between in situ and invasive lesions

Naoto Kohno, Mitsuaki Ishida, Shizuka Ono, Yoshinobu Hirose
Article Number: 138
Published online on: 19 March 2026

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Review Open Access

Disrupted beginnings: Neurodevelopmental outcomes of COVID‑19 lockdowns in early childhood (Review)

Ioanna Giannopoulou, Vasiliki Efstathiou, Maria-Ioanna Stefanou, Panagiota Korkoliakou, James N. Tsoporis, Demetrios A. Spandidos, Emmanouil Rizos
Article Number: 137
Published online on: 16 March 2026

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Retraction Open Access

[Retracted] Icariin inhibits oral squamous cell carcinoma cell proliferation and induces apoptosis via inhibiting the NF‑κB and PI3K/AKT pathways

Ling Sun, Jing Zhang
Article Number: 136
Published online on: 16 March 2026

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Article Open Access

Effects of fullerenol C60 on the liver, heart and brain tissues of streptozotocin‑induced diabetic rats with sepsis

Necmiye Şengel, Ömer Kubat, Laman Farajsoylu, Ahmet Çağri Büyükkasap, Muharrem Atli, Şaban Cem Sezen, Hasan Bostanci, Kürşat Dikmen, Işin Güneş, Fatma Er, Mustafa Kavutçu, Mustafa Arslan
Article Number: 135
Published online on: 13 March 2026

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Article Open Access

Long non‑coding RNA KCNQ1OT1 promotes ovarian cancer cell malignant characteristics by targeting the miR‑140‑5p/KLK10 axis

Renjie Duan, Zhenyu Tao, Shun Tao, Aichen Yang, Xu Yang, Changzheng Li, Xiaoxiang Zhu, Kexin Zhang, Zhuofu Li, Shanjun Tao
Article Number: 134
Published online on: 11 March 2026

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Article

Deciphering the dynamics of the splenium: A comprehensive analysis of flair hyperintensity variations

Ezel Yaltirik Bilgin, Özkan Ünal, Yasin Özdemir, Onur Şimşek
Article Number: 133
Published online on: 09 March 2026

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Article Open Access

Prior curative‑intent treatment strategy affects progression outcomes of first‑line immunotherapy in metastatic non‑small cell lung cancer: A retrospective cohort study

Ruhper Cekin, Didar Senocak, Serdar Arici, Alpaslan Ozgun
Article Number: 132
Published online on: 09 March 2026

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Retraction Open Access

[Retracted] Recent perspectives of electronic medical record systems (Review)

Xiao-Ying Zhang, Peiying Zhang
Article Number: 131
Published online on: 09 March 2026

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Case Report Open Access

Direct venous‑to‑arterial communication as a novel mechanism for ectopic embolism following esophageal variceal embolization: A case report

Youchun Lei, You Ke, Tianwen Yang, Zhengguo Xu
Article Number: 130
Published online on: 06 March 2026

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Case Report

Diagnostic and therapeutic challenges of isolated spinal vasculitis: A case report

Yajun Yao, Ge-Hong Dong, De-Cai Tian
Article Number: 129
Published online on: 06 March 2026

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Article Open Access

Impact of older age on prognosis in hypersensitivity pneumonitis: A systematic review and meta‑analysis

Konstantinos Dodos, Tsampika-Vasileia Kalamara, Vasiliki Therapioti‑Mavroudi, Nikolaos Trakas, Eleni Sklapani, Demetrios A. Spandidos, Alexandru Corlateanu, Vasiliki Epameinondas Georgakopoulou
Article Number: 128
Published online on: 06 March 2026

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Article

Anti‑inflammatory effects of oridonin on an in vitro model using LPS‑treated human intestinal Caco‑2 cells

Maonan Wang, Bo Xu, Linyue Li, Yu Wang, Mingcheng Li
Article Number: 127
Published online on: 03 March 2026

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Case Report

Management after two consecutive suction losses during small‑incision lenticule extraction: A case report

Luanying Wei, Tiantian Qi, Nan Li, Qiang Shi, Shengjian Mi, Cheng Pei
Article Number: 126
Published online on: 03 March 2026

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Case Report Open Access

Hematemesis resulting from mesenteric venous thrombosis: A case report

Chunyu Shi, Zhongmin Li, Lu Pan, Bin Song
Article Number: 125
Published online on: 02 March 2026

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Article

Inhibitory effects of spermidine on lipopolysaccharide‑induced inflammation in RAW 264.7 cells

Hao Yuan, Fang Peng, Yi-Feng Zhou, Si-Xian Wu, Zhen-Yi Long, Ya-Meng Peng, Yi-Zhao Zhou
Article Number: 124
Published online on: 02 March 2026

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Retraction Open Access

[Retracted] Telemedicine in clinical setting (Review)

Xiao-Ying Zhang, Peiying Zhang
Article Number: 123
Published online on: 02 March 2026

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Article

Effects of spironolactone on cytotoxic damage in osteoblasts

So Young Park, Kwang Sik Suh, Hyun-Sook Kim, Soo Jin Yun, Hyunji Sang, Sang Ouk Chin
Article Number: 122
Published online on: 27 February 2026

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Article Open Access

RNU2‑1 gene copy number variations do not affect serum levels of miR‑1246 as a biomarker for lung adenocarcinoma

Makiko Ueda, Shinya Sato, Yohei Miyagi, Toshiko Aiso
Article Number: 121
Published online on: 27 February 2026

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Article Open Access

A laboratory micro‑CT technique is useful to visualize and characterize dermal skin components in a 3D manner

Katarina Lundqvist, Hanna Tufvesson, Lars B. Dahlin, Marius Reichardt, Bodil Ohlsson
Article Number: 120
Published online on: 27 February 2026

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Case Report

A rare case of early‑onset cerebral syphilitic gummata with severe neurological decline in early‑stage syphilis: A case report

Yujie Ji, Shelin Liu, Yunwei Wang, Youcai Zhao, Zheng Cai, Bing Li
Article Number: 119
Published online on: 26 February 2026

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Review Open Access

Organelle homeostasis disruption: A driving force in the progression of cardiomyopathy (Review)

Yuxing Hou, Chao Li, Youyou Chen, Danfeng Zhong, Miaomiao Chai, Lijiao Mo, Senna Lin, Fangfang Huang, Qi Chen
Article Number: 118
Published online on: 26 February 2026

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Journal Cover
June-2026 Volume 31 Issue 6

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Impact Factor: 2.3

Article Open Access

Effects of rok1 gene deletion on mitosis in fission yeast at appropriate and stressful temperatures and the molecular mechanisms

Jiayi He, Mengnan Liu, Jiani Xu, Xiang Ding, Yiling Hou
Article Number: 151
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