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Experimental and Therapeutic Medicine
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
June 2012 Volume 3 Issue 6

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Impact Factor: 2.3

Article Open Access

Prunella vulgaris aqueous extract attenuates IL-1β-induced apoptosis and NF-κB activation in INS-1 cells

Huiping Wu, Ming Gao, Tuanzhu Ha, Jim Kelley, Ada Young, Kevin Breuel
Pages: 919-924
Published online on: 23 March 2012

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Article Open Access

Correlation between efficacy of PSK postoperative adjuvant immunochemotherapy for gastric cancer and expression of MHC class I

Gentaro Ito, Hiroaki Tanaka, Masaichi Ohira, Mami Yoshii, Kazuya Muguruma, Naoshi Kubo, Masakazu Yashiro, Nobuya Yamada, Kiyoshi Maeda, Tetsuji Sawada, Kosei Hirakawa
Pages: 925-930
Published online on: 02 April 2012

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Article Open Access

Membranous and cytoplasmic expression of epidermal growth factor receptor in metastatic pancreatic ductal adenocarcinoma

Takahiro Einama, Shigeto Ueda, Hitoshi Tsuda, Kazuhiro Ogasawara, Kazuo Hatsuse, Osamu Matsubara, Satoru Todo, Junji Yamamoto
Pages: 931-936
Published online on: 15 March 2012

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Article Open Access

Impact of increased erythropoietin receptor expression and elevated serum erythropoietin levels on clinicopathological features and prognosis in renal cell carcinoma

Keiichi Ito, Hidehiko Yoshii, Takako Asano, Akio Horiguchi, Makoto Sumitomo, Masamichi Hayakawa, Tomohiko Asano
Pages: 937-944
Published online on: 13 March 2012

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Article Open Access

Metabonomic signature analysis of cervical carcinoma and precancerous lesions in women by 1H NMR spectroscopy

Ayshamgul Hasim, Mayinuer Ali, Batur Mamtimin, Jun‑Qi  Ma, Qiao-Zhi Li, Abulizi Abudula
Pages: 945-951
Published online on: 12 March 2012

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Article

Intratumoral Wnt2B expression affects tumor proliferation and survival in malignant pleural mesothelioma patients

Masashi Kobayashi, Cheng-Long Huang, Makoto Sonobe, Ryutaro Kikuchi, Masashi Ishikawa, Jiro Kitamura, Ryo Miyahara, Toshi Menju, Shotaro Iwakiri, Kazumi Itoi, Ryoji Yasumizu, Hiroshi Date
Pages: 952-958
Published online on: 12 March 2012

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Article

Genotoxic therapy stimulates error-prone DNA repair in dormant hepatocellular cancer stem cells

Shimpei Nishikawa, Hideshi Ishii, Naotsugu Haraguchi, Yoshihiro Kano, Takahito Fukusumi, Katsuya Ohta, Miyuki Ozaki, Daisuke Sakai, Taroh Satoh, Hiroaki Nagano, Yuichiro Doki, Masaki Mori
Pages: 959-962
Published online on: 22 March 2012

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Article

Parathyroid hormone-related protein expression, in combination with nodal status, predicts bone metastasis and prognosis of breast cancer patients

Keiichi Takagaki, Tsutomu Takashima, Naoyoshi Onoda, Kenji Tezuka, Eiji Noda, Hidemi Kawajiri, Tetsuro Ishikawa, Kosei Hirakawa
Pages: 963-968
Published online on: 21 March 2012

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Article

Post-training consumption of wheat gluten hydrolysate suppresses the delayed onset of muscle injury in soccer players

Kazuhiro Aoki, Yoshimitsu Kohmura, Yoshio Suzuki, Natsue Koikawa, Masafumi Yoshimura, Yukihiro Aoba, Norifumi Fukushi, Keishoku Sakuraba, Isao Nagaoka, Keisuke Sawaki
Pages: 969-972
Published online on: 03 April 2012

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Article

Co-expression of CXCR4 and CD133 proteins is associated with poor prognosis in stage II-III colon cancer patients

Nian-Hua Zhang, Jie Li, Yin Li, Xin-Tao Zhang, Wen-Ting  Liao, Jun-Yi Zhang, Rong Li, Rong-Cheng Luo
Pages: 973-982
Published online on: 27 March 2012

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Article

Significance of survivin expression: Prognostic value and survival in stage III non-small cell lung cancer

Meng Wang, Bao-Gang Liu, Zhao-Yang Yang, Xuan Hong, Gong-Yan Chen
Pages: 983-988
Published online on: 12 March 2012

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Article

Endothelial cell protein C receptor gene 6936A/G polymorphism is associated with venous thromboembolism

Guancheng Yin, Xing Jin, Hanxin Ming, Xiao Zheng, Deqing Zhang
Pages: 989-992
Published online on: 12 March 2012

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Article

Prognostic value of nuclear maspin expression for adjuvant 5-fluorouracil-based chemotherapy in advanced gastric cancer

Ke-Feng Lei, Bing-Ya Liu, Xiao-Long Jin, Yan Guo, Min Ye, Zheng-Gang Zhu
Pages: 993-998
Published online on: 30 March 2012

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Article

Feasibility and effect of ultrasound microbubble-mediated wild-type p53 gene transfection of HeLa cells

Wen-Juan Chen, Zheng-Ai Xiong, Yan Tang, Pei-Ting Dong, Pan Li, Zhi-Gang Wang
Pages: 999-1004
Published online on: 27 March 2012

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Article

Screening and identification of serum proteomic biomarkers for gastric adenocarcinoma

Chibo Liu, Chunqin Pan, Yong Liang
Pages: 1005-1009
Published online on: 14 March 2012

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Article

Survivin expression in human lung cancer and the influence of its downregulation on the biological behavior of human lung cancer cells

Xiang-Qi Chen, Sheng Yang, Ming-Qiang Kang, Zhi-Ying Li, Hui-Shan Lu, Ting-Yan Lin
Pages: 1010-1014
Published online on: 23 March 2012

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Case Report

Hyalinizing trabecular tumor of the thyroid: Case report and review of the literature

Jing Li, Guang-Zhi Yang, Lan-Xiang Gao, Wen-Xiu Yan, Hua Jin, Lin Li
Pages: 1015-1017
Published online on: 28 March 2012

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Article

Continuous administration of recombinant human endostatin (Endostar): A pre-clinical safety study

Ruofan Huang, Qiong Zhan, Xinli Zhou, Zhaohui Chu, Jingwei Jiang, Xiaohua Liang
Pages: 1018-1022
Published online on: 30 March 2012

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Case Report

Syphilis manifesting as a nasopharyngeal carcinoma with cervical lymphadenopathy: A case report

Xinbin Pan, Xiaodong Zhu, Qingdi Quentin Li
Pages: 1023-1025
Published online on: 02 April 2012

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Article

Expression of p14ARF, p15INK4b, p16INK4a and skp2 increases during esophageal squamous cell cancer progression

Peng Bai, Xue Xiao, Juan Zou, Lin Cui, Tri M. Bui Nguyen, Jinsong Liu, Jianguo Xiao, Bin Chang, Jin Wu, He Wang
Pages: 1026-1032
Published online on: 22 March 2012

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Article

TAT-Apoptin induces apoptosis in the human bladder cancer EJ cell line and regulates Bax, Bcl-2, caspase-3 and survivin expression

Jun Li, Haifeng Wang, Zhen Ma, Wenxing Fan, Yanfeng  Li, Bingbing Han, Zhijia Zhang, Jiansong Wang
Pages: 1033-1038
Published online on: 21 March 2012

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Article

microRNA expression pattern and its alteration following celecoxib intervention in human colorectal cancer

Wei Chang Chen, Mao Song Lin, Yu Lan Ye, Heng Jun Gao, Zhen Yun Song, Xiao Ying Shen
Pages: 1039-1048
Published online on: 30 March 2012

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Article

Synergistic impact of Lactobacillus fermentum, Lactobacillus plantarum and vincristine on 1,2-dimethylhydrazine-induced colorectal carcinogenesis in mice

Asha Asha, Devaraja Gayathri
Pages: 1049-1054
Published online on: 02 April 2012

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Article

Comparative serum proteomic analysis involving liver organ-specific metastasis-associated proteins of nasopharyngeal carcinoma

Changchuan Pan, Yalan Tao, Ming Zhao, Wang Li, Zilin Huang, Jing Gao, Yanhen Wu, Jingrui Yu, Peihong Wu, Yunfei Xia, Jin Lu
Pages: 1055-1061
Published online on: 23 March 2012

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Article

Effect of healthcare insurance policy on the quality of life of chronic hepatitis C patients receiving interferon α-2a plus ribavirin therapy

Jing Liu, Chao-Shuang Lin, Wei-Qiang Gan, Yu-Bao Zheng, Zhe-Bin Wu, Zhi-Xin Zhao, Zhi-Liang Gao
Pages: 1062-1066
Published online on: 16 March 2012

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Article

Methylation of the RASSF1A and RARβ genes as a candidate biomarker for lung cancer

Wen Li, Jing Deng, Pei Jiang, Xiaoxi Zeng, Shunqin Hu, Jianxin Tang
Pages: 1067-1071
Published online on: 15 March 2012

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Article

Diagnostic accuracy of vascular endothelial growth factor for malignant pleural effusion: A meta-analysis

Yong-Chun Shen, Meng-Qi Liu, Chun Wan, Lei Chen, Tao Wang, Fu-Qiang Wen
Pages: 1072-1076
Published online on: 14 March 2012

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Article

Downregulation of phosphatase of regenerating liver-3 is involved in the inhibition of proliferation and apoptosis induced by emodin in the SGC-7901 human gastric carcinoma cell line

Zhen-Hua Sun, Ping Bu
Pages: 1077-1081
Published online on: 15 March 2012

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Article

The TNF-α -308G/A polymorphism is associated with migraine risk: A meta-analysis

Lian Gu, Yan Yan, Jianxiong Long, Li Su, Yanling Hu, Qing Chen, Juanjuan Xie, Guangliang Wu
Pages: 1082-1086
Published online on: 30 March 2012

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Article

Expression and subcellular localization of menin in human cancer cells

Feng Ren, Hong-Wei Xu, Yu Hu, Shuang-Hong Yan, Feng Wang, Bao-Wei Su, Qi Zhao
Pages: 1087-1091
Published online on: 29 March 2012

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Article

Autoantibodies against the signal peptide domain of Muc1 in patients with multiple myeloma: Implications for disease diagnosis and prognosis

Riva Kovjazin, Anna Dubnik, Galit Horn, Nechama I. Smorodinsky, Izhar Hardan, Michael Yechiel Shapira, Lior Carmon
Pages: 1092-1098
Published online on: 03 April 2012

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Journal Cover
February-2026 Volume 31 Issue 2

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Impact Factor: 2.3

Case Report Open Access

Bilateral presacral tumors in an adult female patient: A case report and literature review

Yongping Hong, Guofeng Li, Liyu Zhou
Article Number: 61
Published online on: 29 December 2025

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Retraction Open Access

[Retracted] MicroRNA‑34a suppresses breast cancer cell proliferation and invasion by targeting Notch1

Xiaoping Rui, Haibin Zhao, Xianqiu Xiao, Li Wang, Lin Mo, Yao Yao
Article Number: 60
Published online on: 22 December 2025

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Article Open Access

Therapeutic efficacy of quercetin in experimental pulmonary fibrosis: A meta‑analysis

Lanhua Cai, Long Chen, Chunmei Lin
Article Number: 59
Published online on: 22 December 2025

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Article Open Access

N‑(p‑Coumaroyl) serotonin mitigates inflammatory responses in lipopolysaccharide‑stimulated RAW264.7 cells and phorbol 12‑myristate 13‑acetate‑stimulated A549 cells through NF‑κB and MAPK inactivation

Seok Han Yun, Chang Hyeon Jeon, Soo-Jin Park, Hee Jae Lee, Ok-Kyoung Kwon, Jae-Won Lee
Article Number: 58
Published online on: 22 December 2025

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Article

Association of thrombocytopenia with deep vein thrombosis in patients with acute exacerbations of chronic obstructive pulmonary disease: A retrospective study

Yufang Guo, Li Wang, Zexu Wang, Yongjun Wang, Qiuqi Lin, Xiuwei Zhang, Liangquan Wu, Bing Wan
Article Number: 57
Published online on: 22 December 2025

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Article Open Access

Analysis of PANoptosis‑related genes in septic cardiomyopathy by bioinformatics, machine learning and experimental validation

Yiheng Yang, Jiahao Zou, Peng Yang, Zhenzhong Zheng, Qingshan Tian
Article Number: 56
Published online on: 16 December 2025

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Article Open Access

Long‑term effects of orthokeratology on moderate myopia progression in children: A 3‑year prospective study

Yibao Li, Rui Zhang, Yu Su, Rongfeng Liao
Article Number: 55
Published online on: 16 December 2025

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Article Open Access

Metabolic gene polymorphisms and type 2 diabetes mellitus risk: A systematic review and meta‑analyses

Dono Indarto, Tri N. Susilawati, Yuliana H. Suselo, Purwo S. Rejeki, Yuxi Feng, Yohanes C. Wibowo, Melani R. Mahanani
Article Number: 54
Published online on: 16 December 2025

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Article Open Access

Impact of MGMT methylation on overall survival in solid tumors: A systematic review and meta‑analysis

Abdulla Alzibdeh, Ala'a Khanfar, Maysa Al-Hussaini, Ramiz Abuhijlih, Issa Mohamad, Hikmat Abdel-razeq, Fawzi Abuhijla
Article Number: 53
Published online on: 15 December 2025

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Retraction Open Access

[Retracted] MicroRNA‑216b‑3p inhibits lung adenocarcinoma cell growth via regulating PDZ binding kinase/T‑LAK‑cell‑originated protein kinase

Yaqin Chai, Huijun Xue, Yanmei Wu, Xiaomei Du, Zhuohong Zhang, Yinliang Zhang, Lili Zhang, Shuanbao Zhang, Zhiguo Zhang, Zhiwen Xue
Article Number: 52
Published online on: 15 December 2025

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Case Report Open Access

Cardiac mass in a patient with HIV infection: A case report and literature review

Adrian Gradinaru, Andrei Colita, Ionela Muraretu, Mircea Bajdechi, Anca Mihailescu, Carmen Saguna, Radoi Roxana, Adriana-Luminita Gurghean
Article Number: 51
Published online on: 15 December 2025

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Article Open Access

Development and internal validation of a clinical nomogram for predicting bronchopulmonary dysplasia in preterm infants

Yan-Sha Pan, Lan Xiao, Wen-Bin Dong, Jia-Wen Dang
Article Number: 50
Published online on: 09 December 2025

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Retraction Open Access

[Retracted] MicroRNA‑519a inhibits the proliferation and promotes the apoptosis of ovarian cancer cells through targeting signal transducer and activator of transcription 3

Fei Tian, Ligang Jia, Zhaoping Chu, Hua Han, Yuan Zhang, Jianhui Cai
Article Number: 49
Published online on: 09 December 2025

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Case Report Open Access

Appendiceal mucinous tumour resulting in autoamputation of the appendix: A case report and literature review

Chenao Wang, Yufeng Liu, Yaqing Liu, Baicheng Li, Xingdong Hou, Bowei Lu, Zhao Chen, Shili Ning
Article Number: 48
Published online on: 05 December 2025

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Case Report Open Access

Calcifying fibrous tumours of the diaphragm: A case report and literature review

Sijia Guo, Wenya Han, Lingling Yuan, Hansheng Wang, Ge Cheng, Yaxin Tuo, Chuanyong Xiao, Jialong Guo, Meifang Wang
Article Number: 47
Published online on: 05 December 2025

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Case Report

Prolonged remission of SAPHO syndrome with low‑dose leflunomide: A case report and literature review

Angelo Nigro
Article Number: 46
Published online on: 05 December 2025

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Correction Open Access

[Corrigendum] Effects of matrine on the proliferation and apoptosis of vincristine‑resistant retinoblastoma cells

Bowen Zhao, Bin Li, Qian Liu, Fei Gao, Zhibao Zhang, Haixia Bai, Yichen Wang
Article Number: 45
Published online on: 04 December 2025

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Article Open Access

Efficacy of nerve blocks for postoperative analgesia in lung cancer: A meta‑analysis of randomized clinical trials

Jie Wu, Yu-Xin Liu, Shipeng Zhang, Baiping An
Article Number: 44
Published online on: 03 December 2025

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Article

Prenatally diagnosed intra‑abdominal testicular teratoma managed with single‑stage Fowler‑Stephens orchiopexy postnatally: A case report and literature review

Honggang Fang, Guangbei Peng, Xing Liu, Shengde Wu, Yi Hua, Guanghui Wei, Deying Zhang
Article Number: 43
Published online on: 02 December 2025

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Review

Plazomicin: A promising novel antimicrobial in the era of bacterial resistance (Review)

Mohamed Abouelkheir, Ahmed E. Taha, Ibrahim A. Taher, Heba M. Saad Eldien, Gamal Abdelrahman Bakhaat
Article Number: 42
Published online on: 02 December 2025

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Case Report

A novel presentation of minocycline‑induced nail discoloration: A case report

Ke Li, Wenjing Zha, Yitao Qian, Lei Shi
Article Number: 41
Published online on: 01 December 2025

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Article Open Access

Effects of food and gastrointestinal secretions on intestinal integrity in an experimental rat model

Omer Cennet, Akbar Hajiyev, Burcin Şener, Filiz Akbiyik, Cenk Sökmensüer, Osman Abbasoglu
Article Number: 40
Published online on: 01 December 2025

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Article Open Access

The influence of fetal sex on preterm birth risk in gestational diabetes mellitus: A retrospective cohort study

Xuemei Sun, Min Yang, Lingling Wan, Hua Zhong
Article Number: 39
Published online on: 01 December 2025

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Retraction Open Access

[Retracted] circRNA_PTPRA functions as a sponge of miR‑582‑3p to regulate hepatocellular carcinoma cell proliferation, migration, invasion and apoptosis

Yanlin Jin, Yi Zhang, Xiaoming Luo
Article Number: 38
Published online on: 01 December 2025

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Article Open Access

Effects of small incision lenticule extraction and femtosecond laser‑assisted in situ keratomileusis on choroidal thickness and blood flow density in patients with myopia

Shirui Yang, Tiantian Qian, Min Tang, Jing Zhang, Jie Hou, Yahui Dong, Yulin Lei
Article Number: 37
Published online on: 01 December 2025

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Article Open Access

Mammalian target of rapamycin inhibitors as the treatment for steroid‑refractory acute graft‑vs.‑host disease after allogeneic hematopoietic stem cell transplantation: A systematic review and individual patient data meta‑analysis

Yanru Guo, Zhi Li, Yiqun Zhang, Zhijuan Pan, Jiajia Sun, Ying Zhang, Shuting Chang, Zhiping Guo
Article Number: 36
Published online on: 01 December 2025

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Article Open Access

Patients with sickle cell disease and asthma have a higher risk for acute chest syndrome: A systematic review and meta‑analysis of observational studies

Konstantinos Dodos, Tsampika-Vasileia Kalamara, Demetrios A. Spandidos, Alexandru Corlateanu, Vasiliki Epameinondas Georgakopoulou
Article Number: 35
Published online on: 28 November 2025

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Article Open Access

Early enteral nutrition may reduce the incidence of refeeding syndrome for patients with severe corona virus disease 2019 and high nutritional risk

Liuniu Xiao, Xiao Ran, Shusheng Li
Article Number: 34
Published online on: 28 November 2025

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Article Open Access

Outcomes of anti‑VEGF therapy compared with conventional interventions in diabetic retinopathy management

Yong Guo, Rui Yang, Yan Li, Chenjun Guo, Houcheng Liang
Article Number: 33
Published online on: 28 November 2025

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Article Open Access

Pan‑cancer analysis of the oncogenic role of SRY‑related high‑mobility group box protein B5 in human tumors

Yajun Tong, Huini Da, Kewei Tang, Qiang Zhou, Songlian Liu, Leilan Yin, Ling Long, Site Bai, Ludi Ou, Qinghua Yin
Article Number: 32
Published online on: 28 November 2025

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Article Open Access

Inhibition of sclerostin activity promotes bone regeneration in experimental periodontal disease: A systematic review and meta‑analysis of animal models

Miaomiao Yang, Yongqing Ma, Xiaofu Qu, Zhe Qu, Jiang Sun
Article Number: 31
Published online on: 25 November 2025

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Effect of enhanced recovery after surgery‑based perioperative nursing on postoperative pain and recovery in patients with cervical cancer: A retrospective cohort study

Lu Mo, Ruichen Liang, Xianyong Wang, Zhiwei Xiao, Zhongxun Wu, Lihong Chen
Article Number: 30
Published online on: 25 November 2025

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Expression of Concern Open Access

[Expression of Concern] Randomized controlled trial comparing letrozole with laparoscopic ovarian drilling in women with clomiphene citrate‑resistant polycystic ovary syndrome

Wei Liu, Shengnan Dong, Yumei Li, Lihong Shi, Wei Zhou, Yingling Liu, Jie Liu, Yazhong Ji
Article Number: 29
Published online on: 24 November 2025

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March-2026 Volume 31 Issue 3

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Case Report Open Access

Novel variants in STAG2 and PKD1 associate with multiple congenital malformations and autosomal dominant polycystic kidney disease in a Chinese family: A case report and literature review

Qi Yang, Qiang Zhang, Sheng Yi, Xunzhao Zhou, Yiyan Ruan, Shujie Zhang, Shang Yi, Qinle Zhang, Zailng Qin, Jingsi Luo
Article Number: 62
Published online on: 30 December 2025

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