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Experimental and Therapeutic Medicine
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Print ISSN: 1792-0981 Online ISSN: 1792-1015
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
September 2012 Volume 4 Issue 3

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Impact Factor: 2.3

Article

Knockdown of hypoxia-inducible factor-1α accelerates peritoneal dissemination via the upregulation of MMP-1 expression in gastric cancer cell lines

Masatsugu Hiraki, Yoshihiko Kitajima, Keita Kai, Jun Nakamura, Kazuyoshi Hashiguchi, Hirokazu Noshiro, Kohji Miyazaki
Pages: 355-362
Published online on: 06 June 2012

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Article

CXCL12/CXCR4 axis plays pivotal roles in the organ-specific metastasis of pancreatic adenocarcinoma: A clinical study

Weixia Zhong, Weiwei Chen, Dexian Zhang, Jujie Sun, Yuhui Li, Jianbo Zhang, Yongsheng Gao, Wuyuan Zhou, Sheng Li
Pages: 363-369
Published online on: 04 July 2012

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Article

Polysaccharide K suppresses angiogenesis in colon cancer cells

Yoshiki Satoh, Takanori Goi, Toshiyuki Nakazawa, Youhei Kimura, Yasuo Hirono, Kanji Katayama, Akio Yamaguchi
Pages: 370-374
Published online on: 04 July 2012

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Article

Inhibition of hepatic stellate cell proliferation by bone marrow mesenchymal stem cells via regulation of the cell cycle in rat

Shanyu Qin, Haixing Jiang, Sibiao Su, Dongxu Wang, Ziyu Liang, Junhong Zhang, Wen Yang
Pages: 375-380
Published online on: 29 June 2012

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Article

Comparison of the efficacy of transcatheter arterial chemoembolization and sorafenib for advanced hepatocellular carcinoma

Hiroki Nishikawa, Yukio Osaki, Eriko Iguchi, Haruhiko Takeda, Jun Nakajima, Fumihiro Matsuda, Azusa Sakamoto, Shinichiro Henmi, Keiichi Hatamaru, Sumio Saito, Akihiro Nasu, Ryuichi Kita, Toru Kimura
Pages: 381-386
Published online on: 15 June 2012

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Article

Relationship between 8-hydroxydeoxyguanosine levels in placental/umbilical cord blood and maternal/neonatal obstetric factors

Satoko Ebina, Takako Chiba, Takashi Ozaki, Ikuo Kashiwakura
Pages: 387-390
Published online on: 20 June 2012

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Article

Association between body mass index and breast cancer intrinsic subtypes in Japanese women

Kosei Kimura, Satoru Tanaka, Mitsuhiko Iwamoto, Hiroya Fujioka, Yuko Takahashi, Nayuko Satou, Kazuhisa Uchiyama
Pages: 391-396
Published online on: 25 June 2012

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Article

Flow cytometric analysis of Notch1 and Jagged1 expression in normal blood cells and leukemia cells

Eriko Kanamori, Mai Itoh, Naoko Tojo, Takatoshi Koyama, Nobuo Nara, Shuji Tohda
Pages: 397-400
Published online on: 04 July 2012

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Article

Evaluation of a partial optic nerve crush model in rats

Hai-Bo Tan, Xi Shen, Yu Cheng, Qin Jiao, Zi-Jian Yang, Yi-Sheng Zhong
Pages: 401-404
Published online on: 22 June 2012

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Article

Investigation of neural stem cell-specific regulatory promoter elements

Honghua Yuan, Ankang Hu, Li Zhang, Xiaorong Zhu
Pages: 405-408
Published online on: 18 June 2012

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Article

Syzygium aromaticum ethanol extract reduces high‑fat diet-induced obesity in mice through downregulation of adipogenic and lipogenic gene expression

Chang Hwa Jung, Jiyun Ahn, Tae-Il Jeon, Tae Wan Kim, Tae Youl Ha
Pages: 409-414
Published online on: 13 June 2012

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Article

Surgical treatment for hydrosalpinx increases the expression of integrin αvβ3 in the endometrium during the implantation window

Yiping Zhong, Jin Li, Haitao Wu, Ying Ying, Yafeng Liu, Canquan Zhou, Yanwen Xu, Xiaoting Shen, Quan Qi
Pages: 415-418
Published online on: 14 June 2012

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Article

A pilot animal and clinical study of autologous blood solution compared with normal saline for use as an endoscopic submucosal cushion

Wei Wen, Chuanbing Shi, Yan Shi, Guozhong Ji, Ping Wu, Zhining Fan, Faming Zhang
Pages: 419-424
Published online on: 29 June 2012

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Article

A modified rat model of isolated bilateral pulmonary contusion

Shaohua Wang, Zheng Ruan, Jie Zhang, Jin Zheng
Pages: 425-429
Published online on: 18 June 2012

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Article

Sodium hyaluronate as a drug-release system for VEGF 165 improves graft revascularization in anterior cruciate ligament reconstruction in a rabbit model

Jiarong Chen, Liu Yang, Lin Guo, Xiaojun Duan
Pages: 430-434
Published online on: 03 July 2012

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Article

CD133 expression predicts lung metastasis and poor prognosis in osteosarcoma patients: A clinical and experimental study

Aina He, Weixiang Qi, Yujing Huang, Tao Feng, Jie Chen, Yuanjue Sun, Zan Shen, Yang Yao
Pages: 435-441
Published online on: 08 June 2012

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Article

Construction of a novel vector expressing the fusion suicide gene yCDglyTK and hTERT-shRNA and its antitumor effects

Jia Li, Guiying Zhang, Ting Liu, Huan Gu, Lu Yan, Bolin Chen
Pages: 442-448
Published online on: 18 June 2012

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Article

Gorham-Stout syndrome presenting in a 5-year-old girl with a successful bisphosphonate therapeutic effect

Min-Wen Zheng, Min Yang, Jian-Xin Qiu, Xue-Ping Nan, Lu-Yu Huang, Wen-Dong Zhang, Li Gong, Zhi-Zhong Huang
Pages: 449-451
Published online on: 26 June 2012

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Article

Reduction of oxidative stress in liver cancer patients by oral green tea polyphenol tablets during hepatic arterial infusion chemotherapy

Yasutaka Baba, Jun-Ichiro Sonoda, Sadao Hayashi, Nanako Tosuji, Shunro Sonoda, Kanro Makisumi, Masayuki Nakajo
Pages: 452-458
Published online on: 07 June 2012

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Article

Prediction of response to bacillus Calmette-Guérin treatment in non-muscle invasive bladder cancer patients through interleukin-6 and interleukin-10 ratio

Tommaso Cai, Gabriella Nesi, Sandra Mazzoli, Francesca Meacci, Galliano Tinacci, Lorenzo Giuseppe Luciani, Vincenzo Ficarra, Gianni Malossini, Riccardo Bartoletti
Pages: 459-464
Published online on: 05 July 2012

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Article

siRNA targeting decoy receptor 3 enhances the sensitivity of gastric carcinoma cells to 5-fluorouracil

Xiao-Tao Xu, Ze-Zhang Tao, Qi-Bin Song, Yi Yao, Peng Ruan
Pages: 465-468
Published online on: 08 June 2012

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Article

Protective effect of α-lipoic acid on islet cells co-cultured with 3T3L1 adipocytes

Yufan Wang, Weiping Dong, Xiaoying Ding, Feng Wang, Yufei Wang, Xinya Chen, Long Yu, Xiaohua Li, Aifang Zhang, Yongde Peng
Pages: 469-474
Published online on: 07 June 2012

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Article

Reassessment of the prognostic value of the International Prognostic Index and the revised International Prognostic Index in patients with diffuse large B-cell lymphoma: A multicentre study

Hong-Hui Huang, Fei Xiao, Fang-Yuan Chen, Ting Wang, Jun-Min Li, Jian‑Min Wang, Jun-Ning Cao, Chun Wang, Shan-Hua Zou
Pages: 475-480
Published online on: 12 June 2012

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Article

Fish intake and risk of heart failure: A meta‑analysis of five prospective cohort studies

Li-Na Hou, Fei Li, You Zhou, Shi-Huai Nie, Liang Su, Ping‑An Chen, Wan-Long Tan, Ding-Li Xu
Pages: 481-486
Published online on: 08 June 2012

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Article

Telomerase activity assay for the diagnosis of malignant pleural effusion: A meta-analysis

Yong-Chun Shen, Zhen-Ni Chen, Ting Yang, Lei Chen, Tao Wang, Fu-Qiang Wen, Qun Yi
Pages: 487-492
Published online on: 26 June 2012

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Article

Impact of renal denervation on renalase expression in adult rats with spontaneous hypertension

Weihong Jiang, Yunzhong Guo, Lihua Tan, Xiaohong Tang, Qiong Yang, Kan Yang
Pages: 493-496
Published online on: 20 June 2012

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Article

Association of FAS gene polymorphisms with systemic lupus erythematosus: A case-control study and meta-analysis

Man-Man Lu, Qian-Ling Ye, Chen-Chen Feng, Jie Yang, Tao Zhang, Jing  Li, Rui-Xue Leng, Hai-Feng Pan, Hui Yuan, Dong-Qing Ye
Pages: 497-502
Published online on: 28 June 2012

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Article

Endothelin B receptors exert antipruritic effects via peripheral κ-opioid receptors

Wenjin Ji, Jiexian Liang, Zhiwei Zhang
Pages: 503-506
Published online on: 27 June 2012

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Article

Predictive value of the pathological extent of tumor invasion in endoscopic resection margins positive for residual tumor cells in surgically resected specimens of early gastric cancer

Hironori Tsujimoto, Sho Ogata, Yoshihisa Yaguchi, Isao Kumano, Risa  Takahata, Satoshi Ono, Junji Yamamoto, Shigeaki Nagao, Soichiro Miura, Kazuo Hase
Pages: 507-513
Published online on: 03 July 2012

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Article

Association analysis of genetic polymorphisms of factor V, factor VII and fibrinogen β chain genes with human abdominal aortic aneurysm

Katarzyna Oszajca, Konrad Wroński, Grażyna Janiszewska, Małgorzata Bieńkiewicz, Michał Panek, Jacek Bartkowiak, Janusz Szemraj
Pages: 514-518
Published online on: 12 June 2012

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Article

A genetic association analysis of polymorphisms, rs2282695 and rs12373539, in the FOSB gene and papillary thyroid cancer

Sang-Ah Han, Jeong-Yoon Song, Seon-Young Min, Won Seo Park, Mi-Ja Kim, Joo-Ho Chung, Kee Hwan Kwon
Pages: 519-523
Published online on: 08 June 2012

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Article

Expression levels of multidrug resistance-associated protein 4 (MRP4) in human leukemia and lymphoma cell lines, and the inhibitory effects of the MRP-specific inhibitor MK-571 on methotrexate distribution in rats

Kenji Takeuchi, Masakazu Shibata, Eiji Kashiyama, Ken Umehara
Pages: 524-532
Published online on: 29 June 2012

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Article

Nardostachys jatamansi inhibits severe acute pancreatitis via mitogen-activated protein kinases

Gi-Sang Bae, Kyoung-Chel Park, Bon Soon Koo, Il-Joo Jo, Sun  Bok Choi, Ho-Joon Song, Sung-Joo Park
Pages: 533-537
Published online on: 18 June 2012

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Article

Association between the CTLA-4 +49A/G polymorphism and Graves' disease: A meta-analysis

Xiaoyu Si, Xiufeng Zhang, Wenru Tang, Ying Luo
Pages: 538-544
Published online on: 20 June 2012

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Article

Establishment of a conditional transgenic mouse model expressing human uncoupling protein 2 in vascular smooth muscle cells

Shuangtao Ma, De Li, Dachun Yang, Yan Tan, Bing Tang, Feipeng Jin, Sihua Jiang, Xiuchuan Li , Yongjian Yang
Pages: 545-547
Published online on: 25 June 2012

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Journal Cover
June-2026 Volume 31 Issue 6

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Impact Factor: 2.3

Article

Dexmedetomidine alleviates acute lung injury in humans by modulating the JAK1‑STAT3 axis

Xianchao Ding, Daoming Shi, Jieru Wang, Honghua Cai, Zhixin Yan
Article Number: 179
Published online on: 28 April 2026

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Changes in iron metabolism after primary PCI in patients with STEMI and ischemia‑reperfusion injury

Zuoyan Wang, Yang Zhang, Kai Zhang, Xin Huang, Jianjun Peng
Article Number: 178
Published online on: 28 April 2026

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Risk factors for anastomotic leakage after anterior resection of rectal cancer with preservation of the left colic artery

Song Tang, Fan Zhuo, Zhenyu Chen, Huiqiang Cai, Weibin Zhang, Dan Chen
Article Number: 177
Published online on: 28 April 2026

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Retraction Open Access

[Retracted] Combination of magnetic resonance imaging and targeted contrast agent for the diagnosis of myocardial infarction

Jiangjun Qin, Shuchang Zhou, Zhiwei Li, Yinan Chen, Qun Qin, Tao Ai
Article Number: 176
Published online on: 27 April 2026

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Case Report Open Access

Hypertensive crisis during embolization unveils occult catecholamine‑secreting glomus jugulare tumor: A case report and management protocol

Shucai Jiang, Ting Pan, Yanming Qu, Ke Gu, Guanjie Shang, Xiaoning Lan, Weihai Ning, Hongwei Zhang
Article Number: 175
Published online on: 24 April 2026

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Bacterial meningoencephalitis following allogeneic hematopoietic stem cell transplantation: A case report and literature review

Yajun Shi, Ying Han, Jinjin Chen, Heng Liu, Xiaofei Zhang, Rui Song, Xuejie Ma, Qiangsheng Feng, Tao Wu
Article Number: 174
Published online on: 24 April 2026

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Article Open Access

Renal function‑improving action of Pentadecyl®, a multifunctional triglyceride from  , in a mouse model of chronic kidney disease

Keiko Yoneda‑yasui, Hiroshi Nango, Shinpei Fukuhara, Komugi Tsuruta, Koume Nagayama, Tsugumi Tanaka, Yasuko Sakata, Hideaki Ishikawa, Makoto Tsuboi, Hiroko Miyagishi, Yasuhiro Kosuge
Article Number: 173
Published online on: 23 April 2026

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Case Report Open Access

Decitabine monotherapy for pediatric myelodysplastic syndrome: A case report

Zhimin Fan, Nengwen Xu, Alicia Senin, Junyu Zhang
Article Number: 172
Published online on: 23 April 2026

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Retraction Open Access

[Retracted] Salinomycin triggers prostate cancer cell apoptosis by inducing oxidative and endoplasmic reticulum stress via suppressing Nrf2 signaling  

Jianyong Yu, Yang Yang, Shan Li, Peng Meng
Article Number: 171
Published online on: 20 April 2026

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Postmenopausal complete hydatidiform mole: A case report

Emre Uysal
Article Number: 170
Published online on: 20 April 2026

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Identification of inflammation‑related biomarkers for osteoarthritis diagnosis and stratification through bulk and single‑cell RNA‑sequencing integration

Jie Xiao, Weiqing Wang, Xiaotian Li, Shiwei Xu, Bi Zhang, Xin Liao
Article Number: 169
Published online on: 15 April 2026

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Case Report

Detection of overlooked rare thalassemia genotypes: A case series

Chengde Li, Shan Chen, Guangyu Xian, Lixia Liang, Zhifang Lin
Article Number: 168
Published online on: 15 April 2026

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Case Report Open Access

Aggressive fibromatosis resulting in incomplete intestinal obstruction: A case report

Xue Zhang, Ruizeng Feng, Congwen Chen, Wei Liu, Yabing Wei
Article Number: 167
Published online on: 14 April 2026

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Review

Acylation modifications regulate the ovarian microenvironment via metabolic reprogramming and protein relocalization (Review)

Qing Xu, Yong Tan
Article Number: 166
Published online on: 14 April 2026

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Case Report

When fever and headache hide NMOSD: A 29‑year‑old woman with an atypical cerebral presentation: A case report

Dinghao An, Yuxiang Zhang, Wenao Zheng, Yun Xu, Linjie Yu
Article Number: 165
Published online on: 14 April 2026

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Article Open Access

TNF‑α blockade reverses Stevens‑Johnson syndrome/toxic epidermal necrolysis through the RORγt/Foxp3‑mediated restoration of T helper 17/regulatory T cell balance

Zhao Ma, Wei Zhang, Sai-Fei Xi, Ting-Ting Shi, Xin-Chang Xu
Article Number: 164
Published online on: 14 April 2026

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Retraction Open Access

[Retracted] circANRIL reduces vascular endothelial injury, oxidative stress and inflammation in rats with coronary atherosclerosis

Peixia Shi, Hongling Ji, Huajuan Zhang, Jian Yang, Rui Guo, Jianwei Wang
Article Number: 163
Published online on: 14 April 2026

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Article Open Access

Factors affecting central sensitization inventory score before surgery for distal radius fractures

Shoichiro Ishii, Kiyohito Naito, Norizumi Imazu, Takamaru Suzuki, Kenjiro Kawamura, So Kawakita, Tatsuki Itoh, Muneaki Ishijima
Article Number: 162
Published online on: 09 April 2026

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Article Open Access

Systemic immune‑inflammation index and neutrophil‑to‑lymphocyte ratio predict treatment responses in elderly patients with profound sudden deafness

Chong Li, Huili Wu, Hongxia Cui, Yue Li, Zhiming Sun, Siqi Haoliu, Xinfa Wei
Article Number: 161
Published online on: 09 April 2026

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Case Report Open Access

Efficacy analysis of percutaneous cannulated paravertebral approach for microscopic resection of intraspinal schwannomas: A case series

Shaobo Yang, Nianhua Wang
Article Number: 160
Published online on: 09 April 2026

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Case Report Open Access

3D‑printed customized semi‑restrictive elbow prosthesis for severe pseudoarthritis following comminuted fractures of the distal humerus: A case report and review

Bo Zheng, Xiu-Li Zhang, Yu-Xiang Cheng, Ze-Bi He, Peng Li
Article Number: 159
Published online on: 09 April 2026

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Article Open Access

α‑tocopherol in the prevention of ischemic or hemorrhagic stroke: A meta‑analysis

Peng Xu, Pengfei Cheng
Article Number: 158
Published online on: 09 April 2026

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Article Open Access

Preliminary study on symptoms and signs of patients with laryngopharyngeal reflux disease infected with Helicobacter pylori

Haixiang Zhang, Huanhuan Dang, Xin Wang, Yuxiang Zhao, Jinping Wang
Article Number: 157
Published online on: 09 April 2026

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Review Open Access

Autophagy‑epithelial‑mesenchymal transition crosstalk in acute respiratory distress syndrome: Mechanistic insights and therapeutic perspectives (Review)

Yue Zhang, Hongzhi He, Chufan Dong, Qing Guo, Jiuwen Tan, Yonggui Yang, Zhuangbo Guo, Rui Zhang
Article Number: 156
Published online on: 08 April 2026

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Review Open Access

Analysis of low‑benefit subgroups in breast‑conserving surgery: Implications for clinical decision‑making (Review)

Weicheng Lin, Lan Luo, Guiping Guo, Huan Lin
Article Number: 155
Published online on: 08 April 2026

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Case Report

Plexiform fibromyxoma of the lesser curvature of the stomach in a 16‑year‑old adolescent: A case report and literature review

Zhenhua Fu, Peiyao Tao, Da Sun, Xiang Chen
Article Number: 154
Published online on: 08 April 2026

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Case Report Open Access

Retroperitoneal ovarian venous hemangioma: A case report

Jie Tian, Hong Hu, Siyi Chen, Junping Li
Article Number: 153
Published online on: 08 April 2026

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Retraction Open Access

[Retracted] MicroRNA‑140‑5p regulates the proliferation, apoptosis and inflammation of RA FLSs by repressing STAT3

Jiehua Zhu, Jianglin Wang, Jialin Huang, Wensheng Du, Yingzhong He, Hongfei Pan, Junmin Luo
Article Number: 152
Published online on: 07 April 2026

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Article Open Access

Effects of rok1 gene deletion on mitosis in fission yeast at appropriate and stressful temperatures and the molecular mechanisms

Jiayi He, Mengnan Liu, Jiani Xu, Xiang Ding, Yiling Hou
Article Number: 151
Published online on: 02 April 2026

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Review Open Access

Therapeutic potential of allicin against viral infections: Mechanisms and safety profile (Review)

Ming-Jun Yu, Yong Zhu, Wei Zhang, Qiao-Ping Xu, Hai-Ming Wang, Zhao Ma
Article Number: 150
Published online on: 02 April 2026

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Article Open Access

Interacting proteins of AMPK studied using TurboID proximity labeling technology

Xiaoshan Liu, Jieyu Guo, Qiongyao Wang, Wu Liu, Yan Xue, Shuang Guo, Miao Li
Article Number: 149
Published online on: 02 April 2026

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Multi‑omics analysis of glutamine and fish collagen peptides in alleviating post‑antibiotic Streptococcus pneumoniae injury in feline lung cells

Huasong Bai, Tong Liu, Hengyan Wang, Hongchen Jin, Yunliang Li, Zhanzhong Wang
Article Number: 148
Published online on: 30 March 2026

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Retraction Open Access

[Retracted] MicroRNA‑1236‑3p/translationally controlled tumor protein (TPT1) axis participates in congenital hypothyroidism progression by regulating neuronal apoptosis

Tingting Meng, Shiman Shen, Cheng Li, Xuehua Liu
Article Number: 147
Published online on: 30 March 2026

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July-2026 Volume 32 Issue 1

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Retraction Open Access

[Retracted] Synergistic inhibition of leukemia WEHI‑3 cell growth by arsenic trioxide and Hedyotis diffusa Willd extract in vitro and in vivo

Yu-Jui Kuo, Yan-Jin Liu, Tzong-Der Way, Su-Yin Chiang, Jaung-Geng Lin, Jing-Gung Chung
Article Number: 180
Published online on: 29 April 2026

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