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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
November 2012 Volume 6 Issue 5

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review

Abnormal function of monoamine oxidase-A in comorbid major depressive disorder and cardiovascular disease: Pathophysiological and therapeutic implications (Review)

Rodrigo Machado-Vieira, Alan G. Mallinger
Pages: 915-922
Published online on: 04 September 2012

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Review

Mitochondrial DNA and carcinogenesis (Review)

Ludmila Grzybowska-Szatkowska, Brygida Slaska
Pages: 923-930
Published online on: 09 August 2012

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Review

Potential molecular approaches for the early diagnosis of lung cancer (Review)

Chul Ho Oak, Donald Wilson, Hu Jang Lee, Ho-Ju Lim, Eun-Kee Park
Pages: 931-936
Published online on: 21 August 2012

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Article Open Access

Tumor budding is a significant indicator of a poor prognosis in lung squamous cell carcinoma patients

Ryota Masuda, Hiroshi Kijima, Naoko Imamura, Naohiro Aruga, Yusuke  Nakamura, Daisuke Masuda, Haruka Takeichi, Nobusuke Kato, Tomoki  Nakagawa, Makiko Tanaka, Sadaki Inokuchi, Masayuki Iwazaki
Pages: 937-943
Published online on: 27 August 2012

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Article Open Access

Enhanced histamine production through the induction of histidine decarboxylase expression by phorbol ester in Jurkat cells

Yusuke Nagashima, Koichiro Kako, Jun-Dal Kim, Akiyoshi Fukamizu
Pages: 944-948
Published online on: 27 August 2012

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Article Open Access

Grape seed proanthocyanidin extract alleviates ouabain-induced vascular remodeling through regulation of endothelial function

Xiangju Liu, Jie Qiu, Shaohua Zhao, Beian You, Xiang Ji, Yan Wang, Xiaopei Cui, Qian Wang, Haiqing Gao
Pages: 949-954
Published online on: 08 August 2012

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Article

Interleukin-1α induces immunosuppression by mesenchymal stem cells promoting the growth of prostate cancer cells

Jiwen Cheng, Ling Li, Yan Liu, Zhirou Wang, Xiaodong Zhu, Xianzhong Bai
Pages: 955-960
Published online on: 07 August 2012

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Article

Transcriptional regulatory networks in human lung adenocarcinoma

Xiangrui Meng, Peng Lu, Hua Bai, Peng Xiao, Qingxia Fan
Pages: 961-966
Published online on: 14 August 2012

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Article

Icariin inhibits corticosterone-induced apoptosis in hypothalamic neurons via the PI3-K/Akt signaling pathway

Hongying Zhang, Baojun Liu, Jinfeng Wu, Changqing Xu, Jiang Tao, Xiaohong Duan, Yuxue Cao, Jingcheng Dong
Pages: 967-972
Published online on: 21 August 2012

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Article

Expression of BMP2, TLR3, TLR4 and COX2 in colorectal polyps, adenoma and adenocarcinoma

Li Xiang, Shiqi Wang, Xianqing Jin, Wenjuan Duan, Xionghui Ding, Chang Zheng
Pages: 973-976
Published online on: 24 August 2012

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Article

Foxp3 overexpression decreases sensitivity to chemotherapy in mouse Lewis lung cancer cells

Chun Li, Wei Yang, Xiaodong Gai, Yinglin Zhang, Yi Li, Haiying Fu
Pages: 977-982
Published online on: 05 September 2012

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Article

Downregulation of pancreatic-duodenal homeobox 1 expression in breast cancer patients: A mechanism of proliferation and apoptosis in cancer

Jie Ma, Jia Li, Hua Li, Xigang Xiao, Lei Shen, Lin Fang
Pages: 983-988
Published online on: 05 September 2012

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Article

β-elemene acts as an antitumor factor and downregulates the expression of survivin, Bcl-xL and Mta-1

Xian Chen, Yi Wang, Hongmei Luo, Zhigang Luo, Tao Zhang, Ning Yang, Xiangyang Long, Huang Xie, Weibing Qiu, Biao Zhang, Jun Ding, Luoyan Yang
Pages: 989-995
Published online on: 03 August 2012

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Article

Effect of Etiasa on the expression of matrix metalloproteinase-2 and tumor necrosis factor-α in a rat model of ulcerative colitis Retraction in /10.3892/mmr.2025.13513

Jing-Wei Mao, Hai-Ying Tang, Xiao-Yan Tan, Ying-De Wang
Pages: 996-1000
Published online on: 07 August 2012

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Article

Transforming growth factor-1 promotes the transcriptional activation of plasminogen activator inhibitor type 1 in carcinoma-associated fibroblasts

Yu Zhu, Wan-Le Yin, Yu-Feng Ba, Lin Tian, Zhi-Qiang  Gu, Ming-Sheng Zhang, Chu-Nan Zhong
Pages: 1001-1005
Published online on: 07 August 2012

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Article

Knockdown of RAB25 promotes autophagy and inhibits cell growth in ovarian cancer cells

Yingtao Liu, Xiang Tao, Luoqi Jia, Kwai Wa Cheng, Yiling Lu, Yinhua Yu, Youji Feng
Pages: 1006-1012
Published online on: 28 August 2012

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Article

Synergistic increase in the sensitivity of osteosarcoma cells to thermochemotherapy with combination of paclitaxel and etoposide

T. Huang, W. H. Gong, X. C. Li, C. P. Zou, G. J. Jiang, X. H. Li, D. P. Feng
Pages: 1013-1017
Published online on: 03 September 2012

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Article

Osthole suppresses migration and invasion of A549 human lung cancer cells through inhibition of matrix metalloproteinase-2 and matrix metallopeptidase-9 in vitro

Xiao-Man Xu, Yi Zhang, Dan Qu, Xue-Wei Feng, Yu Chen, Li Zhao
Pages: 1018-1022
Published online on: 21 August 2012

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Article

The effect of vascular endothelial growth factor C expression in tumor-associated macrophages on lymphangiogenesis and lymphatic metastasis in breast cancer

Mingxing Ding, Xiaoyan Fu, Haidong Tan, Ruiquan Wang, Zhimei Chen, Shiping Ding
Pages: 1023-1029
Published online on: 21 August 2012

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Article

Adrenomedullin is involved in the progression of colonic adenocarcinoma

Jee-Youn Kim, Won-Do Park, Sun Lee, Jae-Hoon Park
Pages: 1030-1034
Published online on: 24 August 2012

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Article

Th1/Th2/Th17/Treg expression in cultured PBMCs with antiphospholipid antibodies

Jing Xiao, Fufan Zhu, Xinli Liu, Jing Xiong
Pages: 1035-1039
Published online on: 30 August 2012

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Article

Epigallocatechin-3-gallate inhibits bladder cancer cell invasion via suppression of NF-κB‑mediated matrix metalloproteinase-9 expression

Jie Qin, Yunbin Wang, Yu Bai, Kai Yang, Qiqi Mao, Yiwei  Lin, Debo Kong, Xiangyi Zheng, Liping Xie
Pages: 1040-1044
Published online on: 30 August 2012

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Article

Evaluation of the ELOVL4, PRPH2 and ABCA4 genes in patients with Stargardt macular degeneration

Junhui Yi, Shiqiang Li, Xiaoyun Jia, Xueshan Xiao, Panfeng Wang, Xiangming Guo, Qingjiong Zhang
Pages: 1045-1049
Published online on: 04 September 2012

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Article

Knockdown of mediator complex subunit 19 inhibits the growth of ovarian cancer

Yingtao Liu, Xiang Tao, Lingling Fan, Luoqi Jia, Chao Gu, Youji Feng
Pages: 1050-1056
Published online on: 05 September 2012

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Article

Heterogeneity between primary colon carcinoma and paired lymphatic and hepatic metastases

Huanrong Lan, Ketao Jin, Bojian Xie, Na Han, Binbin Cui, Feilin Cao, Lisong Teng
Pages: 1057-1068
Published online on: 28 August 2012

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Article

Association between polymorphisms of the E-selectin gene, hepatitis B virus DNA copies and preS1 antigen in patients with chronic hepatitis B infection

Wei Juan Cai, Liang Yin, Di Zhou, Wen Jiang Cao, Wei Wei Zheng, Lei Sheng, Jiang Cheng
Pages: 1069-1074
Published online on: 16 August 2012

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Article

Evaluation of the effect of glutathione on cisplatin antitumor activity and kidney injury at different administration times

Yan-Yan Xu, Na Jiang, Tong-Shen Liu, Hui-Qing Qu, Tian Wang
Pages: 1075-1080
Published online on: 13 August 2012

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Article

Proteomic analysis of the cerebrospinal fluid in multiple sclerosis and neuromyelitis optica patients

Shoufeng Jiang, Jiong Wu, Yi Yang, Jianren Liu, Yao Ding, Meiping Ding
Pages: 1081-1086
Published online on: 08 August 2012

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Article

CD55 polymorphisms and risk of aspirin‑exacerbated respiratory disease

Jin Sol Lee, Joon Seol Bae, Jeong-Hyun Kim, Jason Yongha Kim, Tae Joon Park, Charisse Flerida Pasaje, Byung-Lae Park, Hyun Sub Cheong, Soo-Taek Uh, An-Soo Jang, Inseon S. Choi, Choon-Sik Park, Hyoung Doo Shin
Pages: 1087-1092
Published online on: 05 September 2012

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Article

Association of dopaminergic/GABAergic genes with attention deficit hyperactivity disorder in children

Guang-Xin Wang, Yan-Hui Ma, Shi-Fu Wang, Guang-Fang Ren, Hui Guo
Pages: 1093-1098
Published online on: 09 August 2012

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Article

Interleukin-17, produced by lymphocytes, promotes tumor growth and angiogenesis in a mouse model of breast cancer

Jiu-Wei Du, Ke-Yi Xu, Li-Yi Fang, Xin-Lan Qi
Pages: 1099-1102
Published online on: 16 August 2012

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Article

Association study of dimethylarginine dimethylaminohydrolase 2 gene polymorphisms and coronary heart disease

Ai-Guo Xu, Rong-Mei Xu, Chang-Qing Lu, Dan-Dan Li, Qin‑Fu Xu, Jing Guo, Xin Fu, Wei Zhao, Meng-Ying Yao
Pages: 1103-1106
Published online on: 16 August 2012

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Article

Correlation of von Willebrand factor gene polymorphism and coronary heart disease

Ai-Guo Xu, Rong-Mei Xu, Chang-Qing Lu, Meng-Ying Yao, Wei Zhao, Xin Fu, Jing Guo, Qin-Fu Xu, Dan-Dan Li
Pages: 1107-1110
Published online on: 16 August 2012

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Article

Gastric bypass surgery alters the mechanisms of insulin resistance in the adipose tissue of GK rats

Jibin Li, Yong Wang, Yong Zhou, Jingang Liu
Pages: 1111-1116
Published online on: 28 August 2012

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Article

Drug screening study using glioma stem-like cells

Xing Feng, Qin Zhou, Chong Liu, Mei-Ling Tao
Pages: 1117-1120
Published online on: 20 August 2012

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Article

DT-13 suppresses MDA-MB-435 cell adhesion and invasion by inhibiting MMP-2/9 via the p38 MAPK pathway

Yuanyuan Zhang, Jihua Liu, Junping Kou, Jun Yu, Boyang Yu
Pages: 1121-1125
Published online on: 24 August 2012

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Article

Butein inhibits the proliferation of breast cancer cells through generation of reactive oxygen species and modulation of ERK and p38 activities

Li-Heng Yang, Ying-Jui Ho, Jing-Feng Lin, Chi-Wei Yeh, Shao-Hsuan Kao, Li-Sung Hsu
Pages: 1126-1132
Published online on: 07 August 2012

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Article

Lentivirus-mediated RNA interference of clusterin enhances the chemosensitivity of EJ bladder cancer cells to epirubicin in vitro Corrigendum in /10.3892/mmr.2021.12267

Jian Lu, Jun-Hang Luo, Jian Pang, Jia-Zheng Cao, Rong‑Hai Wu, Zhu-Ting Tong, Wei Chen, Dan Xie
Pages: 1133-1139
Published online on: 03 August 2012

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Article

Dysfunction of calcium/calmodulin/CaM kinase IIα cascades in the medial prefrontal cortex in post-traumatic stress disorder

Yu Wen, Bin Li, Fang Han, Enhua Wang, Yuxiu Shi
Pages: 1140-1144
Published online on: 07 August 2012

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Article

Effect of fibronectin on HBV infection in primary human fetal hepatocytes in vitro

Fang Wang, Xiaogang Zhang, Jing Zhang, Ling Hui, Yuming Wang, Xiaohong Wang
Pages: 1145-1149
Published online on: 10 August 2012

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Article

Escin inhibits lipopolysaccharide-induced inflammation in human periodontal ligament cells

Shutai Liu, Huaizhou Wang, Caiqing Qiu, Jing Zhang, Taowen Zhang, Wenjuan Zhou, Zhishan Lu, Xiaohui Rausch-Fan, Zhonghao Liu
Pages: 1150-1154
Published online on: 10 August 2012

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Article

The effects of Ang-1, IL-8 and TGF-β1 on the pathogenesis of COPD

Jixu Gao, Bingyan Zhan
Pages: 1155-1159
Published online on: 03 September 2012

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Article

Differential effects of the steaming time and frequency for manufactured red Liriope platyphylla on nerve growth factor secretion ability, nerve growth factor receptor signaling pathway and regulation of calcium concentration

Sun Il Choi, Jun Seo Goo, Ji Eun Kim, So Hee Nam, In Sik Hwang, Hye Ryun Lee, Young  Ju Lee, Hong Joo Son, Hee Seob Lee, Jong Sup Lee, Hak Jin Kim, Dae Youn Hwang
Pages: 1160-1170
Published online on: 08 August 2012

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Article

Association study of ACE and eNOS single nucleotide polymorphisms with Henoch-Schönlein purpura nephritis

Bo Di, Xinyuan Li, Liqun Song, Qianghu Wang, Suyan Liu
Pages: 1171-1177
Published online on: 10 August 2012

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Article

Profiling of miRNAs in pediatric asthma: Upregulation of miRNA-221 and miRNA-485-3p

Feng Liu, Hou-Bing Qin, Bing Xu, Hui Zhou, De-Yu Zhao
Pages: 1178-1182
Published online on: 10 August 2012

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Article

Long-term culture in vitro impairs the immunosuppressive activity of mesenchymal stem cells on T cells

Xue-Yi Li, Jin Ding, Zhao-Hui Zheng, Xiao-Yan Li, Zhen-Biao Wu, Ping Zhu
Pages: 1183-1189
Published online on: 17 August 2012

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Article

Type II cGMP-dependent protein kinase inhibits ERK/JNK-mediated activation of transcription factors in gastric cancer cells

Jianrong Sang, Yongchang Chen, Lu Jiang, Yan Tao, Yan  Wu, Ying Wang, Yueying Li, Ting Lan, Genbao Shao
Pages: 1190-1194
Published online on: 27 August 2012

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Article

Effects of salidroside on exhaustive exercise‑induced oxidative stress in rats

Jiansheng Xu, Ying Li
Pages: 1195-1198
Published online on: 03 September 2012

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Article

Sulforaphane inhibits proliferation by causing cell cycle arrest at the G2/M phase in rabbit articular chondrocytes

Hee-Jeong Jeong, Seon-Mi Yu, Jae-Chang Jung, Song-Ja Kim
Pages: 1199-1203
Published online on: 30 August 2012

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Article

Distinct roles of two alternative splice variants of matrilin-2 in protein oligomerization and proteolysis

Longxuan Li, Liangqing Zhang, Yiming Shao, Guirong Wang, Rujun Gong, Zhengke Wang, Jinwu Peng, Shuhua Wang, David Genochio, Bin Zhao, Junming Luo
Pages: 1204-1210
Published online on: 30 August 2012

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Article

A simple and practical method that prepares high molecular weight DNA ladders

Jun-He Zhang, Rui Yang, Tian-Yun Wang, Wei-Hua Dong, Fang Wang, Li Wang
Pages: 1211-1213
Published online on: 04 September 2012

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Journal Cover
January-2026 Volume 33 Issue 1

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Non‑coding RNAs in epithelial‑mesenchymal transition of renal cell carcinoma (Review)

Ziqiao Liu, Hanshen Zhou, Junxiao Shen, Yiming Qi, Xuke Gong, Cheng Zhang
Article Number: 51
Published online on: 24 November 2025

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Article Open Access

FOXJ3 drives mesenchymal stem cell osteogenic differentiation via the Wnt/β‑catenin pathway: A novel regulator implicated in osteoporosis

Hongwei Xiao, Jianfeng Li, Wei Huang, Yi Qin
Article Number: 50
Published online on: 21 November 2025

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Article Open Access

NEDD4 regulates VEGF signaling and mTOR to promote angiogenesis and the cell cycle in steroid‑induced osteonecrosis of the femoral head

Jian Li, Dong Zhen, Yuhuan Qin, Caifen Guo
Article Number: 49
Published online on: 21 November 2025

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Article Open Access

Glabridin attenuates LTA‑induced alveolar macrophage migration via activation of the Nrf2/HO‑1 pathway

Chih-Hsuan Hsia, Chun-Ming Yang, Chao-Chien Chang, Ting-Lin Yen, Arief Gunawan Darmanto, Chi-Chang Huang, Joen-Rong Sheu
Article Number: 48
Published online on: 21 November 2025

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Review Open Access

Research progress on molecular therapy for glaucoma (Review)

Weiwei Wang, Gangwei Cheng, Qi Zhou, Sheng Wang, Linyi Zhang
Article Number: 47
Published online on: 21 November 2025

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Article Open Access

Natural compounds for the treatment of rheumatoid arthritis based on the ‘gut‑joint axis’ (Review)

Wenjie Hu, Rui Li, Zhongming Zhang
Article Number: 46
Published online on: 20 November 2025

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Article Open Access

TGM1 as a novel signature gene in psoriasis identified by integrative bioinformatics and experimental validation

Pan Guo, Mengke Sun, Jingyu Zhang, Qianshu Yuan, Hong Cui, Junkai Huang, Jing Luo, Qianyu Zhu, Bingxin Zhang, Lizhi Hu
Article Number: 45
Published online on: 20 November 2025

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Article Open Access

CDK1‑induced regulation of p53 phosphorylation at Ser315 mediates cell cycle arrest and apoptosis of macrophages infected with clinical isolates of Mycobacterium tuberculosis

Banghao Sun, Zhenyu Zhao, Qingyu Meng, Luya Pu, Xingyu Jiang, Shuai Li, Fadi Cao, Fan Li
Article Number: 44
Published online on: 20 November 2025

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Article Open Access

High‑intensity exercise training inhibits excessive autophagy in the hyperlipidemic myocardium of ApoE‑/‑ mice via the NAD+‑mediated SIRT1/MFN2 pathway

Shan Gao, Wei Yao, Jin Yang, Yujie Liu, Zuowei Pei
Article Number: 43
Published online on: 18 November 2025

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Correction Open Access

[Corrigendum] Protective effects of metformin against myocardial ischemia‑reperfusion injury via AMPK‑dependent suppression of NOX4

Yan Shi, Shu-Ai Hou
Article Number: 42
Published online on: 17 November 2025

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Article Open Access

Apelin promotes RANKL‑mediated osteoclastogenesis by activating MAPK and NF‑κB pathways

Yu-Han Wang, Yu-Ying Wu, Chun-Hao Tsai, Yi-Chin Fong, Chih-Yuan Ko, Hsien-Te Chen, Yat-Yin Law, Chih-Hsin Tang
Article Number: 41
Published online on: 12 November 2025

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Identification of multimorbidity hub genes for knee osteoarthritis-atherosclerosis and potential clinical applications

Qingyuan Kang, Ping Yuan, Peisen Xie, Wentao Xiao, Liguang Dong, Zhenpeng Guan, Keshi Zhang
Article Number: 40
Published online on: 12 November 2025

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CTSB mediates oxidative stress and intestinal epithelial barrier disruption in intestinal ischemia‑reperfusion injury

Shuang He, Lei Wang, Zhe Wang, Shiyong Yu, Qi Zhu, Yijun Xu, Yuhang Jiang, Yingxia Wu, Honggang Xiang
Article Number: 39
Published online on: 12 November 2025

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Astragaloside IV promotes the apoptosis of pancreatic cancer cells by activating endoplasmic reticulum stress through the PERK/ATF4/CHOP signaling pathway

Yijun Wang, Mengyang Zhao, Shanshan Liu, Rui Zheng, Tianhui Gao
Article Number: 38
Published online on: 11 November 2025

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[Retracted] Baicalin inhibits influenza virus A replication via activation of type I IFN signaling by reducing miR‑146a

Rui Li, Lianxin Wang
Article Number: 37
Published online on: 10 November 2025

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Migrasomes: Emerging players in intercellular communication and disease pathogenesis (Review)

Yuanliang Cao, Quan Wan, Boqi Zhou, Haixin Zeng, Xiaojie Lu
Article Number: 36
Published online on: 10 November 2025

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Diabetic keratopathy and nuclear proteins (Review)

Haiying Xu, Zhi-Liang Jiang, Yuehong Wang, Xiaoli Hou, Weixia Dong, Yanfang Chen, Qiuying Zhang, Xinying Ji, Shaoping Ji, Yalong Dang
Article Number: 35
Published online on: 10 November 2025

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Homocystinuria: Advances in metabolic and molecular therapies targeting homocysteine pathways (Review)

Ayman A. Althubity
Article Number: 34
Published online on: 10 November 2025

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Synovial chondromatosis: Novel advances in understanding the pathogenesis and in diagnostic strategies (Review)

Xingzheng Deng, Shizhang Liu, Huitong Liu
Article Number: 33
Published online on: 10 November 2025

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Protective effects of Notoginsenoside R1 on the ferroptosis of a human non‑small cell lung cancer cell line

Yuejiao Zhang, Zhongshun Mao, Yong Diao
Article Number: 32
Published online on: 06 November 2025

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Unraveling the synergy of inflammation and apoptosis in sepsis-induced acute lung injury: Insights and therapeutic perspectives (Review)

Liwen Zhang, Haoxuan Li, Dongxu Li, Qingqing Dai
Article Number: 31
Published online on: 03 November 2025

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Dihydroalterperylenol from endophytic fungus Alternaria semiverrucosa and its antitumour activity uncovered by transcriptome analysis, molecular docking and molecular dynamics simulations

Mingfei Yang, Yongzhong Lu, Long Han, Zhangjiang He, Jichuan Kang
Article Number: 30
Published online on: 03 November 2025

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[Retracted] Phosphoinositide 3‑kinase/Akt pathway is involved in pingyangmycin‑induced growth inhibition, apoptosis and reduction of invasive potential in EOMA mouse hemangioendothelioma cells

Li-Xia Peng, Ping Zhao, Hong-Sheng Zhao, Er Pan, Bin-Bin Yang, Qin Li
Article Number: 29
Published online on: 03 November 2025

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Tight junction dysfunction and cytoskeletal remodeling in Hirschsprung‑associated enterocolitis: A decade of mechanistic insights and therapeutic prospects (Review)

Shuai Li, Chen Wang, Ling Zhang, Shan Chen, Ying Zhou, Dehua Yang, Kang Li, Yuan Liu, Shuiqing Chi, Yong Wang, Lizhi Li, Shao-Tao Tang
Article Number: 28
Published online on: 03 November 2025

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Involvement of the thioredoxin system in multiple diseases: A focus on mechanisms of action in autophagy and ferroptosis (Review)

Weihua Wang, Yingdong Mou, Dunlin Lu, Shanshan Xu
Article Number: 27
Published online on: 03 November 2025

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MicroRNA‑199a‑3p suppresses non‑small cell lung cancer progression by targeting FTO to enhance m6A‑mediated downregulation of MZF1 and its transcriptional activation of CLDND1

Yuzhen Cui, Xiaoqian Li, Hongkui Zhang, Weiqiang Yuan, Enbo Zhu
Article Number: 26
Published online on: 03 November 2025

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Role of ubiquitin‑proteasome system in preeclampsia (Review)

Chang-Zhu Pei, Xiao-Xing Song, Hao Xu, Kwang-Hyun Baek
Article Number: 25
Published online on: 03 November 2025

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Schisantherin A induces ferroptosis in non‑small cell lung cancer through activation of the YAP/ACSL4/TfR signaling pathway

Wenxiang Zhu, Yeyang Chen, Xiangjian Wu, Xiaoyan Fu, Yongshi He, Yuxia Mo, Qinghua Zhu, Mingwen Tang, Zhiguang Zhai
Article Number: 24
Published online on: 03 November 2025

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The gut‑bone‑cartilage triad: Microbial regulation of the Wnt/β‑catenin signaling pathway in osteoarthritis joint remodeling (Review)

Ruipu Zhang, Liang Zhang, Bin Tian, Yiqun Wang, Xin Kang, Jiang Zheng
Article Number: 23
Published online on: 31 October 2025

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Protective impact of landiolol against acute lung injury following hemorrhagic shock and resuscitation in rats

Risa Sakamoto, Hiroko Shimizu, Ryu Nakamura, Yifu Lu, Yaqiang Li, Emiko Omori, Toru Takahashi, Hiroshi Morimatsu
Article Number: 22
Published online on: 31 October 2025

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Hidden connection: Impact of the gut microbiota on respiratory diseases in children (Review)

Yanhua Han, Yuchao Jia, Lili Chen, Mingyao Zhang
Article Number: 21
Published online on: 29 October 2025

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From renal development to pathology: An analysis of the multilevel role of insulin‑like growth factor 2 (Review)

Yuping Sun, Wenke Hao, Wei Liu, Wenxue Hu
Article Number: 20
Published online on: 29 October 2025

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[Corrigendum] Early anticoagulation therapy for severe burns complicated by inhalation injury in a rabbit model

Zhong-Hua Fu, Guang-Hua Guo, Zhen-Fang Xiong, Xincheng Liao, Ming-Zhuo Liu, Jinhua Luo
Article Number: 19
Published online on: 29 October 2025

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Mucin 2 and unfolded protein response reshape the mucus barrier in inflammatory bowel disease (Review)

Zhiwei Yuan, Zheng Xia, Liyun Ling, Jingzhe Xie, Feng Zhang
Article Number: 18
Published online on: 29 October 2025

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RING finger protein family in leukemia (Review)

Ye Wang, Yue Zhao, Jihong Zhang
Article Number: 17
Published online on: 29 October 2025

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Retinal light perception and biological rhythms: The role of light in sleep and mood from an ophthalmic perspective (Review)

Man Yuan, Hanxiang Liu, Ranjie Zhu, Yuzhen Li, Siyuan Song, Anhuai Yang
Article Number: 16
Published online on: 29 October 2025

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[Retracted] Oxymatrine‑mediated maturation of dendritic cells leads to activation of FOXP3+/CD4+ Treg cells and reversal of cisplatin‑resistance in lung cancer cells

Hui Liu, Manman Zou, Pei Li, Haifeng Wang, Xijun Lin, Jin Ye
Article Number: 15
Published online on: 27 October 2025

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Zinc finger protein 514 promotes esophageal cancer progression by enhancing cell proliferation, migration and invasion

Lin Lv, Xiaoming Sun, Houlu Zhang, Guangxu Wang, Chao Zhang, Haibo Liu, Liangming Zhu
Article Number: 14
Published online on: 24 October 2025

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Effects of zinc carnosine on bone loss in mice with diabetic osteoporosis 

Jingyuan Gao, Hao Yang, Qiangqiang Lian, Yunpeng Hu, Zhou Yang, Lei Xing, Ying Xue, Xiaoli Hou, Faming Tian, Dong Hu
Article Number: 13
Published online on: 24 October 2025

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Rapamycin improves endometriosis‑related infertility involving ovarian senescence via the PPARα/IGFBP2 pathway

Qiongwei Wu, Jiao Fan, Qingjing Sheng, Xiaoying He
Article Number: 12
Published online on: 24 October 2025

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Combining tadalafil and hyperbaric oxygen therapy protects against ovarian ischemia‑reperfusion damage in rats

Mehmet Akif Baktir, Mustafa Ermis, Esra Balcioglu, Betul Yalcin, Enes Karaman, Ahmet Cumaoglu
Article Number: 11
Published online on: 23 October 2025

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Liquid‑liquid phase separation of PHLDB2 promotes oral squamous cell carcinoma metastasis through regulating epithelial mesenchymal transition and PIK3CA expression

Kunyi Chen, Yuhong Wang, Jianing Cui, Qianrui Liu, Xiaoyong Liu, Wenjin Wang, Jinsong Hou
Article Number: 10
Published online on: 22 October 2025

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Mitochondrial gatekeeper in hepatocellular carcinoma: Unraveling the multifaceted roles of VDAC in metabolic reprogramming, apoptosis evasion and therapeutic innovation (Review)

Jie Wang, Yu Liang, Xiaotao Jia, Xinmao Yang, Danning Shi, Yuanchun Wang, Yanfang Pan
Article Number: 9
Published online on: 21 October 2025

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[Retracted] Knockdown of ubiquitin‑specific protease 51 attenuates cisplatin resistance in lung cancer through ubiquitination of zinc‑finger E‑box binding homeobox 1

Feng Zhou, Chunling Du, Donghui Xu, Jinchang Lu, Lei Zhou, Chaomin Wu, Bo Wu, Jianan Huang
Article Number: 8
Published online on: 20 October 2025

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Exploring the role of cytochrome P450 family 1 subfamily B member 1 and quercetin in modulating neuropathic pain after spinal cord injury

Pengyu Zhou, Lu Li, Yu Cao, Jiahao Chen, Chuyin Chen, Xiangsheng Zhang, Jiurong Chen, Yingdong Deng, Ziqiang Lin, Yupei Lai, Suo Wang, Simin Tang, Wenqi Zhang, Peng Sun, Jun Zhou
Article Number: 7
Published online on: 15 October 2025

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R‑loops in hepatocellular carcinoma: Bridging genomic instability and therapeutic opportunity (Review)

Ching-Hua Hsieh, Yueh-Wei Liu, Pei-Chin Chuang
Article Number: 6
Published online on: 15 October 2025

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Role and relevance of exosome-mediated epigenetic regulation in the pathogenesis, diagnosis and treatment of 
cardiovascular diseases (Review)

Yishuo Zhang, Shanshan Zhang, Yijing Li, Wenqi Jin, Liya Zhou, Jing Lu
Article Number: 5
Published online on: 15 October 2025

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PLIN5 deficiency ameliorates metabolic dysfunction‑associated fatty liver disease by inhibiting ferroptosis

Ya Li, Xiaohan Wang, Xuecui Yin, Xiaohui Zhu, Weiqi Cui, Lin Dong, Yu Xia, Ying Wang, Liu Liu, Pengyuan Zheng, Youcai Tang
Article Number: 4
Published online on: 14 October 2025

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Circadian clock genes: Their influence on liver metabolism, disease development and treatment (Review)

Junmin Wang, Mengxing Cao, Shen Li, Wen Pei, Jing Li, Zhen Wang
Article Number: 3
Published online on: 14 October 2025

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MALT1 inhibition by MI‑2 suppresses epithelial‑to‑mesenchymal transition and fibrosis by inactivating the NF‑κB pathway in high glucose‑treated HK‑2 cells

Yating Lan, Jian Ma, Huijun Chen, Chaohong Lan, Na Zhao
Article Number: 2
Published online on: 14 October 2025

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[Retracted] Protective effect of erythropoietin against myocardial injury in rats with sepsis and its underlying mechanisms

Xinliang Zhang, Shimin Dong, Yanjun Qin, Xiaohua Bian
Article Number: 1
Published online on: 14 October 2025

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February-2026 Volume 33 Issue 2

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Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

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Mitophagy and oxidative stress in chronic kidney disease (Review)

Quwu Mushuo, Yihuai Tian, Jianchun Li, Yanqin Qiu, Hui Fan, Qiongdan Hu, Qiong Zhang
Article Number: 61
Published online on: 04 December 2025

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ABCC9 knockdown attenuates isoproterenol‑induced myocardial hypertrophy by inhibiting the PI3K/AKT signaling pathway

Qian Peng, Rui Chang, Linlin Ma, Yanfei Li
Article Number: 60
Published online on: 04 December 2025

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MeCP2 suppresses ferroptosis to drive EMT in retinal pigment epithelial cells: Implications for PVR pathogenesis

Sibei Guo, Yongya Zhang, Xue Li, Xueru Zhao, Yingjuan Liang, Xiaohua Li
Article Number: 59
Published online on: 04 December 2025

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[Corrigendum] Screening for implicated genes in colorectal cancer using whole‑genome gene expression profiling

Long-Ci Sun, Hai-Xin Qian
Article Number: 58
Published online on: 04 December 2025

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Hyperoside prevents osteoporosis by activating the PI3K/AKT signaling pathway to inhibit oxidative stress and promote osteogenesis

Lirong Li, Huaidong Deng, Shabin Zhuan, Boyu Wu, Dawei Xiao
Article Number: 57
Published online on: 03 December 2025

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[Retracted] Interference with Tim‑3 protein expression attenuates the invasion of clear cell renal cell carcinoma and aggravates anoikis

Muming Yu, Bin Lu, Yancun Liu, Ying Me, Lijun Wang, Hui Li
Article Number: 56
Published online on: 01 December 2025

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Acetylshikonin induces ferroptosis via the lipid peroxidation pathway in osteosarcoma cells

Ji-Ying Chen, Guo-Shou Wang, Tsung-Ming Chang, Ju-Fang Liu
Article Number: 55
Published online on: 27 November 2025

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Liver X receptor: A potential target for inflammatory bowel disease and colorectal cancer (Review)

Yingjie Li, Xiaoyan Fu, Meiwen Bai, Jiaqi Zhou, Jiatai Qiu, Hongxia Zhang, Shujuan Liang, Meifang Liu
Article Number: 54
Published online on: 27 November 2025

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lncRNA NEAT1 promotes the proliferation of hemangioma cells by transcriptionally activating β‑catenin via enhancing H3K18 lactylation

Li Yu, Nian Zhou, Xiao-Liang Zhang, Xue-Jing Pang, Lu Xing, Yun-Jing Pu, Li Zhang, Jing-Nan Wu, Hong Shu
Article Number: 53
Published online on: 25 November 2025

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[Retracted] MicroRNA‑206 exerts anti‑oncogenic functions in esophageal squamous cell carcinoma by suppressing the c‑Met/AKT/mTOR pathway

Jin Zhang, Xianen Fa, Qingyong Zhang
Article Number: 52
Published online on: 25 November 2025

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