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Experimental and Therapeutic Medicine
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Print ISSN: 1792-0981 Online ISSN: 1792-1015
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
July-August 2010 Volume 1 Issue 4

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Impact Factor: 2.3

Article Open Access

Myofibroblasts are associated with the progression of scirrhous gastric carcinoma

Yuhiko Fuyuhiro, Masakazu Yashiro, Satoru Noda, Shinichiro Kashiwagi, Junko Matsuoka, Yosuke Doi, Yukihiro Kato, Kazuya Muguruma, Tetsuji Sawada, Kosei Hirakawa
Pages: 547-551
Published online on: 01 July 2010

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Article

Re-assessment of chronic radio-induced tissue damage in a rat hindlimb model

Bérengère Phulpin, Gilles Dolivet, Pierre-Yves Marie, Sylvain Poussier, Patrice Gallet, Agnès Leroux, Pierre Graff, Frederique Groubach, Pierre Bravetti, Jean-Louis Merlin, Nguyen Tran
Pages: 553-560
Published online on: 01 July 2010

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Article

Immunohistochemical assessment of primary breast tumors and metachronous brain metastases, with particular regard to differences in the expression of biological markers and prognosis

Yawara Omoto, Masafumi Kurosumi, Yasuo Hozumi, Hanako Oba, Kaori Kawanowa, Hiroyuki Takei, Yoshikazu Yasuda
Pages: 561-567
Published online on: 01 July 2010

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Case Report

Advanced malignant melanoma responds to Prunus mume Sieb. Et Zucc (Ume) extract: Case report and in vitro study

Shigeto Matsushita, Ko-Ichi Tada, Ko-Ichi Kawahara, Kazuhiro Kawai, Teruto Hashiguchi, Ikuro Maruyama, Takuro Kanekura
Pages: 569-574
Published online on: 01 July 2010

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Article

Bleeding diathesis is associated with an A15T heterozygous mutation in exon 2 of the plasminogen activator inhibitor type 1

Jerzy Jankun, Ewa Skrzypczak-Jankun
Pages: 575-577
Published online on: 01 July 2010

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Article

Rho-kinase regulates prostaglandin D2-stimulated heat shock protein 27 induction in osteoblasts

Kenji Kato, Haruhiko Tokuda, Hideo Natsume, Seiji Adachi, Rie Matsushima-Nishiwaki, Chiho Minamitani, Jun Mizutani, Osamu Kozawa, Takanobu Otsuka
Pages: 579-583
Published online on: 01 July 2010

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Article

Alteration of extracellular superoxide dismutase expression is associated with an aggressive phenotype of oral squamous-cell carcinoma

Hidetaka Yokoe, Hitomi Nomura, Yukio Yamano, Kazuaki Fushimi, Yosuke Sakamoto, Katsunori Ogawara, Masashi Shiiba, Hiroki Bukawa, Katsuhiro Uzawa, Yuichi Takiguchi, Hideki Tanzawa
Pages: 585-590
Published online on: 01 July 2010

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Article

MEK inhibition suppresses cell invasion and migration in ovarian cancers with activation of ERK1/2

Atsuko Katagiri, Kentaro Nakayama, Mohammed Tanjimur Rahman, Munmun Rahman, Shamina Yeasmin, Masako Ishikawa, Kouji Iida, Naomi Nakayama, Khoji Miyazaki
Pages: 591-596
Published online on: 01 July 2010

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Article

HER2/neu protein expression and fine needle breast aspiration from Argentinean patients with non-palpable breast lesions

Wendy Gabriela Domínguez, Héctor Nardi, Héctor Montero, Esteban Vincent, María Marta Corte, Gabriela Andrea Balogh
Pages: 597-602
Published online on: 01 July 2010

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Article

Correlation of obesity and osteoporosis: Effect of free fatty acids on bone marrow-derived mesenchymal stem cell differentiation

Shan Lv, Lin Wu, Peng Cheng, Jing Yu, Aisen Zhang, Juanmin Zha, Juan Liu, Long Wang, Wenjuan Di, Miao Hu, Hanmei Qi, Yujie Li, Guoxian Ding
Pages: 603-610
Published online on: 01 July 2010

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Article

Adjuvant FOLFOX-4 in patients with radically resected gastric cancer: Tolerability and prognostic factors

Chiara Carlomagno, Elide Matano, Roberto Bianco, Carolina Cimminiello, Antonella Prudente, Clorindo Pagliarulo, Anna Crispo, Lucia Cannella, Alfonso De Stefano, Francesco Paolo D'Armiento, Sabino De Placido
Pages: 611-617
Published online on: 01 July 2010

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Article

Prophylactic effect of peptide vaccination against hepatocellular carcinoma associated with hepatitis C virus

Nobukazu Komatsu, Shigeru Yutani, Akira Yamada, Shigeki Shichijo, Kazumi Yoshida, Minoru Itou, Ryoko Kuromatsu, Tatsuya Ide, Masatoshi Tanaka, Michio Sata, Kyogo Itoh
Pages: 619-626
Published online on: 01 July 2010

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Article

Overexpression of endoglin (CD105) is associated with recurrence in radically resected gastric cancer

Yoshihisa Koyama, Hirokazu Okayama, Kensuke Kumamoto, Katsuharu Saito, Izumi Nakamura, Shinji Ohki, Seiichi Takenoshita
Pages: 627-633
Published online on: 01 July 2010

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Article

Investigation of risk factors for prostate cancer patients with bone metastasis based on clinical data

Yoshiaki Yamada, Katsuya Naruse, Kogenta Nakamura, Tomohiro Taki, Motoi Tobiume, Kenji Zennami, Genya Nishikawa, Youko Itoh, Yoshitaka Muramatsu, Hiroshi Nanaura, Miho Nishimura, Kazuko Takii, Adnan Odhafa Kh. Adham, Nobuaki Honda
Pages: 635-639
Published online on: 01 July 2010

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Article Open Access

Usefulness of intraoperative touch smear cytology in breast-conserving surgery

Kazuhiro Simiyoshi, Takehiro Nohara, Mitsuhiko Iwamoto, Satoru Tanaka, Kosei Kimura, Yuko Takahashi, Yoshitaka Kurisu, Motomu Tsuji, Nobuhiko Tanigawa
Pages: 641-645
Published online on: 01 July 2010

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Article

G2/M accumulation in prostate cancer cell line PC-3 is induced by Cdc25 inhibitor 7-chloro-6-(2-morpholin-4-ylethylamino) quinoline-5, 8-dione (DA 3003-2)

Kaoru Nemoto
Pages: 647-650
Published online on: 01 July 2010

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Article

Neoadjuvant intraarterial chemotherapy for stage IIB-IIIB cervical cancer in Japanese women

Shoji Kaku, Kentaro Takahashi, Yoshitaka Murakami, Shirou Wakinoue, Tetsuya Nakagawa, Yoshihiko Shimizu, Nobuyuki Kita, Yoichi Noda, Takashi Murakami
Pages: 651-655
Published online on: 01 July 2010

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Article

Sensitive quantitative assay for point mutations in the rat H-ras gene based on single nucleotide primer extension

Yoshihisa Yano, Tomohiro Yano, Anna Kinoshita, Ai Matoba, Tadayoshi Hasuma, Hideki Wanibuchi, Keiichirou Morimura, Shuzo Otani, Shoji Fukushima
Pages: 657-661
Published online on: 01 July 2010

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Article

Relationship between the production of autoantibodies to oxidized low-density lipoprotein and hepatic steatosis in patients with chronic hepatitis C

Takashi Himoto, Hirohito Yoneyama, Akihiro Deguchi, Kazutaka Kurokohchi, Michio Inukai, Hisashi Masugata, Fuminori Goda, Shoichi Senda, Reiji Haba, Seishiro Watanabe, Mikio Nishioka, Tsutomu Masaki
Pages: 663-668
Published online on: 01 July 2010

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Article Open Access

Effects of irbesartan on 24-h blood pressure changes and urinary albumin levels in Japanese outpatients

Tadashi Arai, Mihoko Senda, Hitomi Yokoyama, Kikuko Yasuda
Pages: 669-673
Published online on: 01 July 2010

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Article

Augmentation of the anticancer effects of proteasome inhibitors by combination with sodium butyrate in human colorectal cancer cells

M.S. I. Abaza
Pages: 675-693
Published online on: 01 July 2010

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Article

p27 modulates tropism of mesenchymal stem cells toward brain tumors

Yun Gao, Chunyu Gu, Shaoyi Li, Tsutomu Tokuyama, Naoki Yokota, Keiichi I. Nakayama, Masatoshi Kitagawa, Hiroki Namba
Pages: 695-699
Published online on: 01 July 2010

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Article

Association between polymorphisms of the DBH and DAT1 genes and attention deficit hyperactivity disorder in children from Jordan

Mohammad Y. Gharaibeh, Sajida Batayneh, Omar F. Khabour, Azhar Daoud
Pages: 701-705
Published online on: 01 July 2010

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Article

Insulin resistance derived from zinc deficiency in non-diabetic patients with chronic hepatitis C

Takashi Himoto, Hirohito Yoneyama, Akihiro Deguch, Kazutaka Kurokohchi, Michio Inukai, Hisashi Masugata, Fuminori Goda, Shoichi Senda, Seishiro Watanabe, Satoru Kubota, Shigeki Kuriyama, Tsutomu Masaki
Pages: 707-711
Published online on: 01 July 2010

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Article

Comparative photodynamic therapy study using two phthalocyanine derivatives

Edith Inés Yslas, Laura Natalia Milla, Silvia Romanini, Edgardo Néstor Durantini, Mabel Bertuzzi, Viviana Alicia Rivarola
Pages: 713-718
Published online on: 01 July 2010

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Article

Association of endothelial nitric oxide synthase polymorphisms with coronary artery disease in Korean individuals with or without diabetes mellitus

Jeehyeon Bae, In Jai Kim, Seung Ho Hong, Jung Hoon Sung, Sang Wook Lim, Dong Hoon Cha, Yong Wook Cho, Doyeun Oh, Nam Keun Kim
Pages: 719-724
Published online on: 01 July 2010

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Journal Cover
February-2026 Volume 31 Issue 2

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Impact Factor: 2.3

Case Report Open Access

Bilateral presacral tumors in an adult female patient: A case report and literature review

Yongping Hong, Guofeng Li, Liyu Zhou
Article Number: 61
Published online on: 29 December 2025

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Retraction Open Access

[Retracted] MicroRNA‑34a suppresses breast cancer cell proliferation and invasion by targeting Notch1

Xiaoping Rui, Haibin Zhao, Xianqiu Xiao, Li Wang, Lin Mo, Yao Yao
Article Number: 60
Published online on: 22 December 2025

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Article Open Access

Therapeutic efficacy of quercetin in experimental pulmonary fibrosis: A meta‑analysis

Lanhua Cai, Long Chen, Chunmei Lin
Article Number: 59
Published online on: 22 December 2025

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Article Open Access

N‑(p‑Coumaroyl) serotonin mitigates inflammatory responses in lipopolysaccharide‑stimulated RAW264.7 cells and phorbol 12‑myristate 13‑acetate‑stimulated A549 cells through NF‑κB and MAPK inactivation

Seok Han Yun, Chang Hyeon Jeon, Soo-Jin Park, Hee Jae Lee, Ok-Kyoung Kwon, Jae-Won Lee
Article Number: 58
Published online on: 22 December 2025

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Article

Association of thrombocytopenia with deep vein thrombosis in patients with acute exacerbations of chronic obstructive pulmonary disease: A retrospective study

Yufang Guo, Li Wang, Zexu Wang, Yongjun Wang, Qiuqi Lin, Xiuwei Zhang, Liangquan Wu, Bing Wan
Article Number: 57
Published online on: 22 December 2025

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Article Open Access

Analysis of PANoptosis‑related genes in septic cardiomyopathy by bioinformatics, machine learning and experimental validation

Yiheng Yang, Jiahao Zou, Peng Yang, Zhenzhong Zheng, Qingshan Tian
Article Number: 56
Published online on: 16 December 2025

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Article Open Access

Long‑term effects of orthokeratology on moderate myopia progression in children: A 3‑year prospective study

Yibao Li, Rui Zhang, Yu Su, Rongfeng Liao
Article Number: 55
Published online on: 16 December 2025

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Article Open Access

Metabolic gene polymorphisms and type 2 diabetes mellitus risk: A systematic review and meta‑analyses

Dono Indarto, Tri N. Susilawati, Yuliana H. Suselo, Purwo S. Rejeki, Yuxi Feng, Yohanes C. Wibowo, Melani R. Mahanani
Article Number: 54
Published online on: 16 December 2025

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Article Open Access

Impact of MGMT methylation on overall survival in solid tumors: A systematic review and meta‑analysis

Abdulla Alzibdeh, Ala'a Khanfar, Maysa Al-Hussaini, Ramiz Abuhijlih, Issa Mohamad, Hikmat Abdel-razeq, Fawzi Abuhijla
Article Number: 53
Published online on: 15 December 2025

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Retraction Open Access

[Retracted] MicroRNA‑216b‑3p inhibits lung adenocarcinoma cell growth via regulating PDZ binding kinase/T‑LAK‑cell‑originated protein kinase

Yaqin Chai, Huijun Xue, Yanmei Wu, Xiaomei Du, Zhuohong Zhang, Yinliang Zhang, Lili Zhang, Shuanbao Zhang, Zhiguo Zhang, Zhiwen Xue
Article Number: 52
Published online on: 15 December 2025

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Case Report Open Access

Cardiac mass in a patient with HIV infection: A case report and literature review

Adrian Gradinaru, Andrei Colita, Ionela Muraretu, Mircea Bajdechi, Anca Mihailescu, Carmen Saguna, Radoi Roxana, Adriana-Luminita Gurghean
Article Number: 51
Published online on: 15 December 2025

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Article Open Access

Development and internal validation of a clinical nomogram for predicting bronchopulmonary dysplasia in preterm infants

Yan-Sha Pan, Lan Xiao, Wen-Bin Dong, Jia-Wen Dang
Article Number: 50
Published online on: 09 December 2025

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Retraction Open Access

[Retracted] MicroRNA‑519a inhibits the proliferation and promotes the apoptosis of ovarian cancer cells through targeting signal transducer and activator of transcription 3

Fei Tian, Ligang Jia, Zhaoping Chu, Hua Han, Yuan Zhang, Jianhui Cai
Article Number: 49
Published online on: 09 December 2025

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Case Report Open Access

Appendiceal mucinous tumour resulting in autoamputation of the appendix: A case report and literature review

Chenao Wang, Yufeng Liu, Yaqing Liu, Baicheng Li, Xingdong Hou, Bowei Lu, Zhao Chen, Shili Ning
Article Number: 48
Published online on: 05 December 2025

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Case Report Open Access

Calcifying fibrous tumours of the diaphragm: A case report and literature review

Sijia Guo, Wenya Han, Lingling Yuan, Hansheng Wang, Ge Cheng, Yaxin Tuo, Chuanyong Xiao, Jialong Guo, Meifang Wang
Article Number: 47
Published online on: 05 December 2025

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Case Report

Prolonged remission of SAPHO syndrome with low‑dose leflunomide: A case report and literature review

Angelo Nigro
Article Number: 46
Published online on: 05 December 2025

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Correction Open Access

[Corrigendum] Effects of matrine on the proliferation and apoptosis of vincristine‑resistant retinoblastoma cells

Bowen Zhao, Bin Li, Qian Liu, Fei Gao, Zhibao Zhang, Haixia Bai, Yichen Wang
Article Number: 45
Published online on: 04 December 2025

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Article Open Access

Efficacy of nerve blocks for postoperative analgesia in lung cancer: A meta‑analysis of randomized clinical trials

Jie Wu, Yu-Xin Liu, Shipeng Zhang, Baiping An
Article Number: 44
Published online on: 03 December 2025

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Article

Prenatally diagnosed intra‑abdominal testicular teratoma managed with single‑stage Fowler‑Stephens orchiopexy postnatally: A case report and literature review

Honggang Fang, Guangbei Peng, Xing Liu, Shengde Wu, Yi Hua, Guanghui Wei, Deying Zhang
Article Number: 43
Published online on: 02 December 2025

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Review

Plazomicin: A promising novel antimicrobial in the era of bacterial resistance (Review)

Mohamed Abouelkheir, Ahmed E. Taha, Ibrahim A. Taher, Heba M. Saad Eldien, Gamal Abdelrahman Bakhaat
Article Number: 42
Published online on: 02 December 2025

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Case Report

A novel presentation of minocycline‑induced nail discoloration: A case report

Ke Li, Wenjing Zha, Yitao Qian, Lei Shi
Article Number: 41
Published online on: 01 December 2025

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Article Open Access

Effects of food and gastrointestinal secretions on intestinal integrity in an experimental rat model

Omer Cennet, Akbar Hajiyev, Burcin Şener, Filiz Akbiyik, Cenk Sökmensüer, Osman Abbasoglu
Article Number: 40
Published online on: 01 December 2025

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Article Open Access

The influence of fetal sex on preterm birth risk in gestational diabetes mellitus: A retrospective cohort study

Xuemei Sun, Min Yang, Lingling Wan, Hua Zhong
Article Number: 39
Published online on: 01 December 2025

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Retraction Open Access

[Retracted] circRNA_PTPRA functions as a sponge of miR‑582‑3p to regulate hepatocellular carcinoma cell proliferation, migration, invasion and apoptosis

Yanlin Jin, Yi Zhang, Xiaoming Luo
Article Number: 38
Published online on: 01 December 2025

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Article Open Access

Effects of small incision lenticule extraction and femtosecond laser‑assisted in situ keratomileusis on choroidal thickness and blood flow density in patients with myopia

Shirui Yang, Tiantian Qian, Min Tang, Jing Zhang, Jie Hou, Yahui Dong, Yulin Lei
Article Number: 37
Published online on: 01 December 2025

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Article Open Access

Mammalian target of rapamycin inhibitors as the treatment for steroid‑refractory acute graft‑vs.‑host disease after allogeneic hematopoietic stem cell transplantation: A systematic review and individual patient data meta‑analysis

Yanru Guo, Zhi Li, Yiqun Zhang, Zhijuan Pan, Jiajia Sun, Ying Zhang, Shuting Chang, Zhiping Guo
Article Number: 36
Published online on: 01 December 2025

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Article Open Access

Patients with sickle cell disease and asthma have a higher risk for acute chest syndrome: A systematic review and meta‑analysis of observational studies

Konstantinos Dodos, Tsampika-Vasileia Kalamara, Demetrios A. Spandidos, Alexandru Corlateanu, Vasiliki Epameinondas Georgakopoulou
Article Number: 35
Published online on: 28 November 2025

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Article Open Access

Early enteral nutrition may reduce the incidence of refeeding syndrome for patients with severe corona virus disease 2019 and high nutritional risk

Liuniu Xiao, Xiao Ran, Shusheng Li
Article Number: 34
Published online on: 28 November 2025

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Article Open Access

Outcomes of anti‑VEGF therapy compared with conventional interventions in diabetic retinopathy management

Yong Guo, Rui Yang, Yan Li, Chenjun Guo, Houcheng Liang
Article Number: 33
Published online on: 28 November 2025

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Article Open Access

Pan‑cancer analysis of the oncogenic role of SRY‑related high‑mobility group box protein B5 in human tumors

Yajun Tong, Huini Da, Kewei Tang, Qiang Zhou, Songlian Liu, Leilan Yin, Ling Long, Site Bai, Ludi Ou, Qinghua Yin
Article Number: 32
Published online on: 28 November 2025

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Article Open Access

Inhibition of sclerostin activity promotes bone regeneration in experimental periodontal disease: A systematic review and meta‑analysis of animal models

Miaomiao Yang, Yongqing Ma, Xiaofu Qu, Zhe Qu, Jiang Sun
Article Number: 31
Published online on: 25 November 2025

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Article Open Access

Effect of enhanced recovery after surgery‑based perioperative nursing on postoperative pain and recovery in patients with cervical cancer: A retrospective cohort study

Lu Mo, Ruichen Liang, Xianyong Wang, Zhiwei Xiao, Zhongxun Wu, Lihong Chen
Article Number: 30
Published online on: 25 November 2025

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Expression of Concern Open Access

[Expression of Concern] Randomized controlled trial comparing letrozole with laparoscopic ovarian drilling in women with clomiphene citrate‑resistant polycystic ovary syndrome

Wei Liu, Shengnan Dong, Yumei Li, Lihong Shi, Wei Zhou, Yingling Liu, Jie Liu, Yazhong Ji
Article Number: 29
Published online on: 24 November 2025

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March-2026 Volume 31 Issue 3

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Case Report Open Access

Novel variants in STAG2 and PKD1 associate with multiple congenital malformations and autosomal dominant polycystic kidney disease in a Chinese family: A case report and literature review

Qi Yang, Qiang Zhang, Sheng Yi, Xunzhao Zhou, Yiyan Ruan, Shujie Zhang, Shang Yi, Qinle Zhang, Zailng Qin, Jingsi Luo
Article Number: 62
Published online on: 30 December 2025

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