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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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International Journal of Molecular Medicine

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
February 2013 Volume 31 Issue 2

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

The role of peptide YY in gastrointestinal diseases and disorders (Review)

Magdy El-Salhy, Tarek Mazzawi, Doris Gundersen, Jan Gunnar Hatlebakk, Trygve Hausken
Pages: 275-282
Published online on: 21 December 2012

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B7-H3 overexpression in pancreatic cancer promotes tumor progression

Xin Zhao, De-Chun Li, Xin-Guo Zhu, Wen-Juan Gan, Zhi Li, Feng Xiong, Zi-Xiang Zhang, Guang-Bo Zhang, Xue-Guang Zhang, Hua Zhao
Pages: 283-291
Published online on: 13 December 2012

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Article

Short-term mechanical stress inhibits osteoclastogenesis via suppression of DC-STAMP in RAW264.7 cells

Sumika Kameyama, Yoshitaka Yoshimura, Takeshi Kameyama, Takashi Kikuiri, Mino Matsuno, Yoshiaki Deyama, Kuniaki Suzuki, Junichiro Iida
Pages: 292-298
Published online on: 21 December 2012

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The potential of recombinant vesicular stomatitis virus-mediated virotherapy against metastatic colon cancer

Minoru Yamaki, Katsunori Shinozaki, Takemasa Sakaguchi, Marcia Meseck, Oliver Ebert, Hideki Ohdan, Savio L.C. Woo
Pages: 299-306
Published online on: 06 December 2012

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Article

Forced mastication increases survival of adult neural stem cells in the hippocampal dentate gyrus

Yuki Akazawa, Takamasa Kitamura, Yuri Fujihara, Yoshitaka Yoshimura, Masato Mitome, Tomokazu Hasegawa
Pages: 307-314
Published online on: 18 December 2012

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Article

CD133 silencing inhibits stemness properties and enhances chemoradiosensitivity in CD133-positive liver cancer stem cells

Xi Lan, Yong-Zhong Wu, Yong Wang, Fu-Rong Wu, Chun‑BaoΒ  Zang, Chuan Tang, Shu Cao, Shao-Lin Li
Pages: 315-324
Published online on: 06 December 2012

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Article

Lactoferrin protects against prion protein-induced cell death in neuronal cells by preventing mitochondrial dysfunction

Yang-Gyu Park, Jae-Kyo Jeong, Ju-Hee Lee, You-Jin Lee, Jae-Won Seol, Shang-Jin Kim, Tai-Young Hur, Young-Hun Jung, Seog-Jin Kang, Sang-Youel Park
Pages: 325-330
Published online on: 29 November 2012

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Article

Kaempferol suppresses lipid accumulation in macrophages through the downregulation of cluster of differentiationΒ 36 and the upregulation of scavenger receptor classΒ B typeΒ I and ATP-binding cassette transportersΒ A1 andΒ G1

Xiu-Ying Li, Ling-Xi Kong, Juan Li, Hai-Xia He, Yuan-Da Zhou
Pages: 331-338
Published online on: 05 December 2012

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Article

Synergistic effects of histone deacetylase inhibitor in combination with mTOR inhibitor in the treatment of prostate carcinoma

Paul Thelen, Lisa Krahn, Felix Bremmer, ArneΒ  Strauss, Ralph Brehm, Hagen Loertzer
Pages: 339-346
Published online on: 21 December 2012

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Article

Comparison of three different HCV genotyping methods: Core, NS5B sequence analysis and line probe assay

Qingxian Cai, Zhixin Zhao, Ying Liu, Xiaoqiong Shao, Zhiliang Gao
Pages: 347-352
Published online on: 12 December 2012

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Article

Novel rotundic acid derivatives: Synthesis, structural characterization and in vitro antitumor activity

Yu Chen, Yu-Fang He, Min-Lun Nan, Wen-Yi Sun, Jie Hu, Ai Cui, Fan Li, Fang Wang
Pages: 353-360
Published online on: 06 December 2012

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Article

Anti-metastatic effect of polysaccharide isolated from Colocasia esculenta is exerted through immunostimulation

Hye-Ryung Park, Hyun-Sun Lee, Sun Young Cho, Yoon-Sook Kim, Kwang-Soon Shin
Pages: 361-368
Published online on: 27 December 2012

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Article

Intracellular-delivery of a single-chain antibody against hepatitis B core protein via cell-penetrating peptide inhibits hepatitis B virus replication in vitro

Yunhao Xun, Qingchun Pan, Zhenghao Tang, Xiaohua Chen, Yongsheng Yu, Min Xi, Guoqing Zang
Pages: 369-376
Published online on: 12 December 2012

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Article

Combination of oncolytic adenovirus and endostatin inhibits human retinoblastoma in an in vivo mouse model

Huiping Wang, Fang Wei, Huiming Li, Xunda Ji, Shuxia Li, Xiafang Chen
Pages: 377-385
Published online on: 29 November 2012

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Article

Immune activation and antitumor response of ar-turmerone on P388D1 lymphoblast cell implanted tumors

Donghee Kim, Yongjoon Suh, Hyunsook Lee, Yongkyu Lee
Pages: 386-392
Published online on: 29 November 2012

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Cis-guggulsterone inhibits the IKK/NF-ΞΊB pathway, whereas trans-guggulsterone inhibits MAPK/AP-1 in MCF‑7 breast cancer cells: Guggulsterone regulates MMP‑9 expression in an isomer-specific manner

Eun-Mi Noh, Eun Yong Chung, Hyun Jo Youn, Sung Hoo Jung, Hyun Hur, Young-Rae Lee, Jong-Suk Kim
Pages: 393-399
Published online on: 14 December 2012

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Article

Cathepsin L stimulates autophagy and inhibits apoptosis of ox-LDL-induced endothelial cells: Potential role in atherosclerosis

Dang-Heng Wei, Xiao-Ying Jia, Yang-Hui Liu, Feng-Xia Guo, Zhi-Han Tang, Xiao-Hong Li, Zuo Wang, Lu-Shan Liu, Gui-Xue Wang, Zhi-Sheng Jian, Chang-Geng Ruan
Pages: 400-406
Published online on: 03 December 2012

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Article

Direct comparison of the potency of human mesenchymal stem cells derived from amnion tissue, bone marrow and adipose tissue at inducing dermal fibroblast responses to cutaneous wounds

Xiaoyu Liu, Zhe Wang, Rui Wang, Feng Zhao, Ping Shi, Yide Jiang, Xining Pang
Pages: 407-415
Published online on: 30 November 2012

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Article

Co-administration of prostaglandin E1 with somatostatin attenuates acute liver damage after massive hepatectomy in rats via inhibition of inflammatory responses, apoptosis and endoplasmic reticulum stress

Changjun Jia, Chaoliu Dai, Xianmin Bu, Songlin Peng, Feng Xu, Yongqing Xu, Yang Zhao
Pages: 416-422
Published online on: 14 December 2012

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Article

Programmed cell death-1 deficiency results in atrial remodeling in C57BL/6 mice

Guoqiang Fu, Yizhan Cao, Jun Lu, Jun Li, Li Liu, Hongtao Wang, Feifei Su, Qiangsun Zheng
Pages: 423-429
Published online on: 19 December 2012

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Article

Collagen-targeting parathyroid hormone-related peptide promotes collagen binding and in vitro chondrogenesis in bone marrow-derived MSCs

Xiao-Cheng Wu, Bo Huang, Jian Wang, Chang-Qing Li, Yue Zhou
Pages: 430-436
Published online on: 19 December 2012

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Article

Adenosine and inosine exert cytoprotective effects in an in vitro model of liver ischemia-reperfusion injury

Katalin MΓ³dis, Domokos GerΕ‘, Rita Stangl, OlivΓ©r Rosero, Attila SzijΓ‘rtΓ³, GΓ‘bor Lotz, Petra MohΓ‘csik, Petra Szoleczky, Ciro Coletta, Csaba SzabΓ³
Pages: 437-446
Published online on: 04 December 2012

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Article

Platelet-derived growth factor-D induces expression of cyclooxygenase-2 in rat mesangial cells through activation of PI3K/PKB and PKCs

Yu-Kyoung Park, Byeong-Churl Jang, Misun Choi
Pages: 447-452
Published online on: 18 December 2012

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Article

Downregulation of Ξ³-catenin inhibits CML cell growth and potentiates the response of CML cells to imatinib through Ξ²-catenin inhibition

Chang-Chun Niu, Chen Zhao, Zhen-Dong Yang, Xiao-Li Zhang, Wei-Ru Wu, Jing Pan, Zhi-Qiang Li, Wei Ding, Zhong Yang, Wei-Ke Si
Pages: 453-458
Published online on: 06 December 2012

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Article

Microarray-based analysis of the gene expression profile in GC-1 spg cells transfected with spermatogenesis associated gene 12

Yiting Lin, Zhiwen Liu, Xuanming Liu, Yunsheng Zhang, Zhuoxian Rong, Dan Li
Pages: 459-466
Published online on: 27 December 2012

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Article

A novel dual oxidase maturation factor 2 gene mutation for congenital hypothyroidism

Ru-Hai Yi, Wen-Bin Zhu, Li-Yong Yang, Lan Lan, Yao Chen, Jin-Fu Zhou, Jing Wang, Yue-Qing Su
Pages: 467-470
Published online on: 24 December 2012

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Article

The effects of exogenous H2O2 on cell death, reactive oxygen species and glutathione levels in calf pulmonary artery and human umbilical vein endothelial cells

Woo Hyun Park
Pages: 471-476
Published online on: 18 December 2012

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Article

Decursin inhibits UVB-induced MMP expression in human dermal fibroblasts via regulation of nuclear factor-ΞΊB

Bo-Mi Hwang, Eun-Mi Noh, Jong-Suk Kim, Jeong-Mi Kim, Jin-Ki Hwang, Hye-Kyung Kim, Jae-Seon Kang, Do-Sung Kim, Han-Jung Chae, Yong-Ouk You, Kang-Beom Kwon, Young-Rae Lee
Pages: 477-483
Published online on: 04 December 2012

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Article

Mesenchymal stem cells modified with miR-126 release angiogenic factors and activate Notch ligand Delta-like-4, enhancing ischemic angiogenesis and cell survival

Feng Huang, Xiao Zhu, Xin-Qun Hu, Zhen-Fei Fang, Liang Tang, Xiao-Ling Lu, Sheng-Hua Zhou
Pages: 484-492
Published online on: 03 December 2012

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Article

Inhibitory effects of paeoniflorin on lysophosphatidylcholine-induced inflammatory factor production in human umbilical vein endothelial cells

Jian-Zhe Li, Jian-Hua Wu, Shu-Yi Yu, Qing-Rui Shao, Xiao-Min Dong
Pages: 493-497
Published online on: 13 December 2012

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Journal Cover
February-2026 Volume 57 Issue 2

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

miR‑205: A dual regulator of angiogenesis in health and disease (Review)

Maria Oltra, Miriam MartΓ­nez‑Santos, Maria Ybarra, Maria Pires, Chiara Ceresoni, Clara Gomis‑Coloma, Cristina Medina‑Trillo, Javier Sancho, Jorge Barcia
Article Number: 51
Published online on: 29 December 2025

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Astragaloside IV: A multipotent phytochemical for treating fibrotic diseases (Review)

Mingyu Wu, Ke Li, Jiabin Wu, Qiuyu Zhang, Xiaotong Ma, Wei Dai, Haoyang Gao, Xianyi Ding, Wenhong Wang, Weihua Xiao
Article Number: 50
Published online on: 24 December 2025

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Activating transcription factors: Orchestrators of macrophage biology in pathological settings (Review)

Yue-Chen Liu, Jia-Wei Zhao, Xiong-Tao Yue, Qi-Jie Chen, Shan-Jie Rong, Shi-Wei Liu, Fei Sun, Chun-Liang Yang, Cong-Yi Wang
Article Number: 49
Published online on: 24 December 2025

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Role of SIRT3 in digestive system diseases and therapeutic prospects (Review)

Jiajia Li, Qian Liu, Shun Yao, Xin Li, Li Zhang, Yongfeng Wang, Guorong Wen, Jiaxing An, Hai Jin, Biguang Tuo
Article Number: 48
Published online on: 22 December 2025

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Recombinant ADAMTS‑1 promotes muscle regeneration accompanied by downregulation of Notch signaling

Jin-Hwa Kim, Sang-Hyup Lee, Sang-Yoon Kim, Jeong-Won Kim, Ji-Soo Jeong, Eun-Hye Chung, Su-Ha Lee, Chang-Yeop Kim, Bong-Keun Choi, Je-Won Ko, Tae-Won Kim
Article Number: 47
Published online on: 22 December 2025

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A comprehensive review on pain: Model, target, therapy, and prospect (Review)

Chenyu Chang, Xutao Wu, Kejia Liu, Lei Wang, Mozili Adu, Qingyuan Lin, Huilian Huang, Qinge Ma, Rongrui Wei, Xiaoyun Wang, Wenmin Liu
Article Number: 46
Published online on: 17 December 2025

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Retraction Open Access

[Retracted] Curculigoside attenuates myocardial ischemia‑reperfusion injury by inhibiting the opening of the mitochondrial permeability transition pore

Yanbing Zhao, Yuxuan Guo, Yuqiong Chen, Shuang Liu, Nan Wu, Dalin Jia
Article Number: 45
Published online on: 15 December 2025

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Nanomaterials and exercise interventions: A synergistic approach for atherosclerosis therapy (Review)

Quanquan Zhou, Ge‑Lin Zhang, Weitong Sun, Jiayi Cai, Li-Hua Yu
Article Number: 44
Published online on: 10 December 2025

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Selective autophagic degradation of glycolytic activator PFKFB3 contributes to maintaining intestinal epithelial barrier in inflammatory bowel disease

Yiyang Pan, Feng Yang, Liucan Wang, Tianshu Yang, Guangsheng Du, Cong Xu, Hua Yang, Min Yu, Weidong Xiao
Article Number: 43
Published online on: 10 December 2025

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Lactylation‑mediated ferroptosis: A novel mechanism and therapeutic prospects in human diseases (Review)

Zhengjun Lin, Yugang Zou, Songzhu Zou, Kunming Wen
Article Number: 42
Published online on: 08 December 2025

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Dual role of lactate in ferroptosis: Mechanisms, pathophysiology and therapeutic opportunities (Review)

Qian Yu, Yu Kuang, Jie He, Li Yang, Xinjie Li, Hao Yu
Article Number: 41
Published online on: 08 December 2025

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Retraction Open Access

[Retracted] MicroRNA‑493‑5p promotes apoptosis and suppresses proliferation and invasion in liver cancer cells by targeting VAMP2

Guannan Wang, Xiaosan Fang, Meng Han, Xiaoming Wang, Qiang Huang
Article Number: 40
Published online on: 08 December 2025

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FGF4 alleviates the lung cell damage caused by high glucose via AMPK‑PGC‑1 signaling axis in vitro and in vivo

Qiujuan Fu, Yongfang Ou, Qin Wu, Jue Gong, Feixia Li, Tuxing Wang, Zhitai Lin, Kejie Huang, Jianlong Xie
Article Number: 39
Published online on: 05 December 2025

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STOML2 interacts with PHB to activate the MEK/ERK signaling pathway and mediates autophagy‑related proteins in the progression of hepatocellular carcinoma

Haoyang Hu, Haozhe Zhang, Shuai Han, Jianli Chen, Ying Xie
Article Number: 38
Published online on: 04 December 2025

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HMGB1 mediates low-dose ionizing radiation-induced Wnt/β-catenin activation in SRA01/04 cells: Mechanistic clues to early cataractogenesis

Ping Wang, Chunnan Piao, Dong Yan, Yingxue He, Yaru Li, Li Fan, Mei Tian
Article Number: 37
Published online on: 04 December 2025

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FBXO22 promotes hepatocellular carcinoma progression via paracrine myo‑inositol‑induced M2‑type polarization of macrophages

Liangliang Bai, Jing Xiong, Sihai Chen, Jiahao Hu, Meixia Zhang, Bimin Li, Jing Hu, Mingyan He
Article Number: 36
Published online on: 02 December 2025

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Review Open Access

Branched‑chain amino acid metabolism and bone metabolism: Implications for osteoporosis pathogenesis and therapeutic strategies (Review)

Qi Xiao, Haimin Zeng, Ruhui Yang, Yuxin Zhan, Fangzhen Lin, Bofan Chen, Xiang Chen
Article Number: 35
Published online on: 02 December 2025

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Mitochondria-associated endoplasmic reticulum membranes: Emerging regulators of cardiac microvascular ischemia/reperfusion injury (Review)

Yan Wang, Baowei Feng, Yanting Wu, Zongle Sun, Hao Yuan, Wei Chen, Chang Zhao, Zhi Liu
Article Number: 34
Published online on: 02 December 2025

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Role of matrix metalloproteinases in the invasion of glioblastoma and drug interventions (Review)

Bohao Zheng, Ying Han, Haiying Zhang
Article Number: 33
Published online on: 01 December 2025

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Review

Bridging bench to bedside: Exosome‑based strategies for endometriosis diagnosis and treatment (Review)

Wanmeng Chen, Yujiu Ma, Xudong Zhang, Siwen Zhang, Shanshan Wu, Yimeng Lu, Jichun Tan
Article Number: 32
Published online on: 01 December 2025

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Retraction Open Access

[Retracted] miR‑381 functions as a tumor suppressor by targeting ETS1 in pancreatic cancer

Guanen Qiao, Jing Li, Jun Wang, Zhaoyang Wang, Wei Bian
Article Number: 31
Published online on: 01 December 2025

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Journal Cover
March-2026 Volume 57 Issue 3

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

ZG16B: A key regulator of tumor progression and immune microenvironment modulation in cancer (Review)

Xing-Ming Chen, Yu-Bo Liang, Jin-Xiang Zuo, Zi-Sheng Yang, Le-Yu Zhang, Xin-Yu Zhang, Ping Wan, Yang Ke
Article Number: 58
Published online on: 09 January 2026

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[Retracted] Silica nanoparticles induce cardiomyocyte apoptosis via the mitochondrial pathway in rats following intratracheal instillation

Zhongjun Du, Shangya Chen, Guanqun Cui, Ye Yang, Enguo Zhang, Qiang Wang, Martin F. Lavin, Abrey J. Yeo, Cunxiang Bo, Yu Zhang, Chao Li, Xiaoshan Liu, Xu Yang, Cheng Peng, Hua Shao
Article Number: 57
Published online on: 05 January 2026

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Role of cuproptosis in digestive system tumors (Review)

Li Zhang, Yongpeng Cheng, Lulu Tang, Jiaxing Zhu, Biguang Tuo
Article Number: 56
Published online on: 02 January 2026

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Environmental exposure to air pollution and climate: Intersecting the impact on ear and nose health and chemosensory function (Review)

Yu-Chen Zhang, Lei Zhang, Ping-Ting Zhou, Zi-Hui Xie, Wen-Jie Zhang, Min Fan, Yan-Xun Han, Ye-Hai Liu, Yu-Chen Liu
Article Number: 55
Published online on: 31 December 2025

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Role and mechanisms of ferroptosis in cognitive impairment: From molecular pathways to therapeutic targets (Review)

Shenghui Ge, Deyue Kong, Shuyue Fan, Yi Luo, Xiao Yin, Zehua Jin, Wenqing Xia, Jianhua Ma
Article Number: 54
Published online on: 30 December 2025

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