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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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International Journal of Molecular Medicine

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
February 2013 Volume 31 Issue 2

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

The role of peptide YY in gastrointestinal diseases and disorders (Review)

Magdy El-Salhy, Tarek Mazzawi, Doris Gundersen, Jan Gunnar Hatlebakk, Trygve Hausken
Pages: 275-282
Published online on: 21 December 2012

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Article Open Access

B7-H3 overexpression in pancreatic cancer promotes tumor progression

Xin Zhao, De-Chun Li, Xin-Guo Zhu, Wen-Juan Gan, Zhi Li, Feng Xiong, Zi-Xiang Zhang, Guang-Bo Zhang, Xue-Guang Zhang, Hua Zhao
Pages: 283-291
Published online on: 13 December 2012

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Article

Short-term mechanical stress inhibits osteoclastogenesis via suppression of DC-STAMP in RAW264.7 cells

Sumika Kameyama, Yoshitaka Yoshimura, Takeshi Kameyama, Takashi Kikuiri, Mino Matsuno, Yoshiaki Deyama, Kuniaki Suzuki, Junichiro Iida
Pages: 292-298
Published online on: 21 December 2012

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Article

The potential of recombinant vesicular stomatitis virus-mediated virotherapy against metastatic colon cancer

Minoru Yamaki, Katsunori Shinozaki, Takemasa Sakaguchi, Marcia Meseck, Oliver Ebert, Hideki Ohdan, Savio L.C. Woo
Pages: 299-306
Published online on: 06 December 2012

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Article

Forced mastication increases survival of adult neural stem cells in the hippocampal dentate gyrus

Yuki Akazawa, Takamasa Kitamura, Yuri Fujihara, Yoshitaka Yoshimura, Masato Mitome, Tomokazu Hasegawa
Pages: 307-314
Published online on: 18 December 2012

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Article

CD133 silencing inhibits stemness properties and enhances chemoradiosensitivity in CD133-positive liver cancer stem cells

Xi Lan, Yong-Zhong Wu, Yong Wang, Fu-Rong Wu, Chun‑Bao  Zang, Chuan Tang, Shu Cao, Shao-Lin Li
Pages: 315-324
Published online on: 06 December 2012

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Article

Lactoferrin protects against prion protein-induced cell death in neuronal cells by preventing mitochondrial dysfunction

Yang-Gyu Park, Jae-Kyo Jeong, Ju-Hee Lee, You-Jin Lee, Jae-Won Seol, Shang-Jin Kim, Tai-Young Hur, Young-Hun Jung, Seog-Jin Kang, Sang-Youel Park
Pages: 325-330
Published online on: 29 November 2012

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Article

Kaempferol suppresses lipid accumulation in macrophages through the downregulation of cluster of differentiation 36 and the upregulation of scavenger receptor class B type I and ATP-binding cassette transporters A1 and G1

Xiu-Ying Li, Ling-Xi Kong, Juan Li, Hai-Xia He, Yuan-Da Zhou
Pages: 331-338
Published online on: 05 December 2012

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Article

Synergistic effects of histone deacetylase inhibitor in combination with mTOR inhibitor in the treatment of prostate carcinoma

Paul Thelen, Lisa Krahn, Felix Bremmer, Arne  Strauss, Ralph Brehm, Hagen Loertzer
Pages: 339-346
Published online on: 21 December 2012

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Article

Comparison of three different HCV genotyping methods: Core, NS5B sequence analysis and line probe assay

Qingxian Cai, Zhixin Zhao, Ying Liu, Xiaoqiong Shao, Zhiliang Gao
Pages: 347-352
Published online on: 12 December 2012

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Article

Novel rotundic acid derivatives: Synthesis, structural characterization and in vitro antitumor activity

Yu Chen, Yu-Fang He, Min-Lun Nan, Wen-Yi Sun, Jie Hu, Ai Cui, Fan Li, Fang Wang
Pages: 353-360
Published online on: 06 December 2012

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Article

Anti-metastatic effect of polysaccharide isolated from Colocasia esculenta is exerted through immunostimulation

Hye-Ryung Park, Hyun-Sun Lee, Sun Young Cho, Yoon-Sook Kim, Kwang-Soon Shin
Pages: 361-368
Published online on: 27 December 2012

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Article

Intracellular-delivery of a single-chain antibody against hepatitis B core protein via cell-penetrating peptide inhibits hepatitis B virus replication in vitro

Yunhao Xun, Qingchun Pan, Zhenghao Tang, Xiaohua Chen, Yongsheng Yu, Min Xi, Guoqing Zang
Pages: 369-376
Published online on: 12 December 2012

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Article

Combination of oncolytic adenovirus and endostatin inhibits human retinoblastoma in an in vivo mouse model

Huiping Wang, Fang Wei, Huiming Li, Xunda Ji, Shuxia Li, Xiafang Chen
Pages: 377-385
Published online on: 29 November 2012

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Article

Immune activation and antitumor response of ar-turmerone on P388D1 lymphoblast cell implanted tumors

Donghee Kim, Yongjoon Suh, Hyunsook Lee, Yongkyu Lee
Pages: 386-392
Published online on: 29 November 2012

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Cis-guggulsterone inhibits the IKK/NF-κB pathway, whereas trans-guggulsterone inhibits MAPK/AP-1 in MCF‑7 breast cancer cells: Guggulsterone regulates MMP‑9 expression in an isomer-specific manner

Eun-Mi Noh, Eun Yong Chung, Hyun Jo Youn, Sung Hoo Jung, Hyun Hur, Young-Rae Lee, Jong-Suk Kim
Pages: 393-399
Published online on: 14 December 2012

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Article

Cathepsin L stimulates autophagy and inhibits apoptosis of ox-LDL-induced endothelial cells: Potential role in atherosclerosis

Dang-Heng Wei, Xiao-Ying Jia, Yang-Hui Liu, Feng-Xia Guo, Zhi-Han Tang, Xiao-Hong Li, Zuo Wang, Lu-Shan Liu, Gui-Xue Wang, Zhi-Sheng Jian, Chang-Geng Ruan
Pages: 400-406
Published online on: 03 December 2012

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Article

Direct comparison of the potency of human mesenchymal stem cells derived from amnion tissue, bone marrow and adipose tissue at inducing dermal fibroblast responses to cutaneous wounds

Xiaoyu Liu, Zhe Wang, Rui Wang, Feng Zhao, Ping Shi, Yide Jiang, Xining Pang
Pages: 407-415
Published online on: 30 November 2012

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Article

Co-administration of prostaglandin E1 with somatostatin attenuates acute liver damage after massive hepatectomy in rats via inhibition of inflammatory responses, apoptosis and endoplasmic reticulum stress

Changjun Jia, Chaoliu Dai, Xianmin Bu, Songlin Peng, Feng Xu, Yongqing Xu, Yang Zhao
Pages: 416-422
Published online on: 14 December 2012

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Article

Programmed cell death-1 deficiency results in atrial remodeling in C57BL/6 mice

Guoqiang Fu, Yizhan Cao, Jun Lu, Jun Li, Li Liu, Hongtao Wang, Feifei Su, Qiangsun Zheng
Pages: 423-429
Published online on: 19 December 2012

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Article

Collagen-targeting parathyroid hormone-related peptide promotes collagen binding and in vitro chondrogenesis in bone marrow-derived MSCs

Xiao-Cheng Wu, Bo Huang, Jian Wang, Chang-Qing Li, Yue Zhou
Pages: 430-436
Published online on: 19 December 2012

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Article

Adenosine and inosine exert cytoprotective effects in an in vitro model of liver ischemia-reperfusion injury

Katalin Módis, Domokos Gerő, Rita Stangl, Olivér Rosero, Attila Szijártó, Gábor Lotz, Petra Mohácsik, Petra Szoleczky, Ciro Coletta, Csaba Szabó
Pages: 437-446
Published online on: 04 December 2012

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Article

Platelet-derived growth factor-D induces expression of cyclooxygenase-2 in rat mesangial cells through activation of PI3K/PKB and PKCs

Yu-Kyoung Park, Byeong-Churl Jang, Misun Choi
Pages: 447-452
Published online on: 18 December 2012

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Article

Downregulation of γ-catenin inhibits CML cell growth and potentiates the response of CML cells to imatinib through β-catenin inhibition

Chang-Chun Niu, Chen Zhao, Zhen-Dong Yang, Xiao-Li Zhang, Wei-Ru Wu, Jing Pan, Zhi-Qiang Li, Wei Ding, Zhong Yang, Wei-Ke Si
Pages: 453-458
Published online on: 06 December 2012

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Article

Microarray-based analysis of the gene expression profile in GC-1 spg cells transfected with spermatogenesis associated gene 12

Yiting Lin, Zhiwen Liu, Xuanming Liu, Yunsheng Zhang, Zhuoxian Rong, Dan Li
Pages: 459-466
Published online on: 27 December 2012

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Article

A novel dual oxidase maturation factor 2 gene mutation for congenital hypothyroidism

Ru-Hai Yi, Wen-Bin Zhu, Li-Yong Yang, Lan Lan, Yao Chen, Jin-Fu Zhou, Jing Wang, Yue-Qing Su
Pages: 467-470
Published online on: 24 December 2012

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Article

The effects of exogenous H2O2 on cell death, reactive oxygen species and glutathione levels in calf pulmonary artery and human umbilical vein endothelial cells

Woo Hyun Park
Pages: 471-476
Published online on: 18 December 2012

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Article

Decursin inhibits UVB-induced MMP expression in human dermal fibroblasts via regulation of nuclear factor-κB

Bo-Mi Hwang, Eun-Mi Noh, Jong-Suk Kim, Jeong-Mi Kim, Jin-Ki Hwang, Hye-Kyung Kim, Jae-Seon Kang, Do-Sung Kim, Han-Jung Chae, Yong-Ouk You, Kang-Beom Kwon, Young-Rae Lee
Pages: 477-483
Published online on: 04 December 2012

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Article

Mesenchymal stem cells modified with miR-126 release angiogenic factors and activate Notch ligand Delta-like-4, enhancing ischemic angiogenesis and cell survival

Feng Huang, Xiao Zhu, Xin-Qun Hu, Zhen-Fei Fang, Liang Tang, Xiao-Ling Lu, Sheng-Hua Zhou
Pages: 484-492
Published online on: 03 December 2012

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Article

Inhibitory effects of paeoniflorin on lysophosphatidylcholine-induced inflammatory factor production in human umbilical vein endothelial cells

Jian-Zhe Li, Jian-Hua Wu, Shu-Yi Yu, Qing-Rui Shao, Xiao-Min Dong
Pages: 493-497
Published online on: 13 December 2012

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Journal Cover
March-2026 Volume 57 Issue 3

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

Ginkgolide C alleviates atherosclerosis via activating Nrf2 to inhibit ROS‑dependent NLRP3 inflammasome activation

Rui Zhang
Article Number: 75
Published online on: 27 January 2026

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Review Open Access

MicroRNA‑microbiome cross‑kingdom networks drive inflammatory bowel disease through dynamic regulatory ecosystems (Review)

Liping Liang, Xiaoyan Liu, Bang Li, Huyi Lei, Zibo Tang, Shijie Mai, Chenghai Yang, Yongjian Zhou, Shaoheng Zhang, Le Liu
Article Number: 74
Published online on: 27 January 2026

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Review Open Access

Mechanistic insights into pancreatic cancer progression from circadian rhythm disruption and gut microbiota dysbiosis (Review)

Yang Liu, Yongfeng Li, Heng Ma, Shichang Deng, Chao Cheng
Article Number: 73
Published online on: 26 January 2026

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Retraction Open Access

[Retracted] miR‑124‑3p inhibits the viability and motility of glioblastoma multiforme by targeting RhoG  

Shan Cai, Chao-Jia Shi, Jian-Xiang Lu, Yan-Pei Wang, Tian Yuan, Xiang-Peng Wang
Article Number: 72
Published online on: 26 January 2026

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Review Open Access

Natural products as multi‑target therapies for sepsis‑induced myocardial dysfunction (Review)

Fei Tang, Dong Liu, Shi-Chao Zhu, Hui-Min Zhou, Xue-Wen Qiu
Article Number: 71
Published online on: 22 January 2026

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Review Open Access

MTHFR‑folate axis as a modulator of the epigenetic landscape in autoimmune diseases (Review)

Pablo Michael Navarro‑Rodríguez, Ramón Francisco Bajeca‑Serrano, Francisco Javier Turrubiates‑Hernández, Hazael Ramiro Ceja‑Gálvez, Jorge Hernández‑Bello, Cristian Oswaldo Hernández‑Ramírez, Saúl Ramírez‑de Los Santos, José Francisco Muñoz‑Valle
Article Number: 70
Published online on: 22 January 2026

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Article Open Access

Natural compound 5,7,8‑trimethoxyflavone mitigates radiation‑induced lung injury by suppressing EMT and PI3K/Akt pathway

Cui-Cui Gong, Hua-Kang Li, Yuan-Zhen Mi, Jun-Yang Chen, Zeng-Yi Fang, Shun-Lian Fu, Li Quan, Bing Lin, Jin-Yi Lang, Qiu Chen, Ke Xu, Mei-Hua Chen
Article Number: 69
Published online on: 21 January 2026

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Review Open Access

Epigenetic dysregulation of B‑cells in autoimmune diseases and lymphomas (Review)

Yuxing Li, Yujiao Gong, Jiaxing Zhao, Rensen Ran
Article Number: 68
Published online on: 21 January 2026

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Review Open Access

Research progress on the effects of macrophage‑derived exosomes on muscle factors IGF‑1 and FGF‑2 mediating musculoskeletal crosstalk molecular signaling pathway on bone metabolism (Review)

Ruo-Mei Cui, Mai Zheng, Jian-Bin Hong, Zheng-Xiang Wang, Yu-Fang Cun, Shu-Ji Gao, Yan-Lin Zhu, Zi-Bin Yang, Ming-Wei Liu
Article Number: 67
Published online on: 21 January 2026

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Expression of Concern Open Access

[Expression of Concern] Long non‑coding RNA SNHG20 promotes bladder cancer via activating the Wnt/β‑catenin signalling pathway

Qingsong Zhao, Saiyue Gao, Qingyan Du, Ye Liu
Article Number: 66
Published online on: 21 January 2026

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Review Open Access

Mangiferin in human disease: Multifaceted mechanisms and applications (Review)

Yaling Dai, Qiuling Huang, Mengquan Tan, Zhifu Wang, Cai Jiang, Zheng Liu, Shenghang Zhang, Siyuan Song
Article Number: 65
Published online on: 21 January 2026

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Article

Deciphering the CAF‑LCN2 axis: Key to overcoming anti‑PD‑L1 immunotherapy resistance in lung cancer

Dan Xiao, Jing Yang, Jianying Zhou, Zhenzhen Hu, Ting Zhang
Article Number: 64
Published online on: 19 January 2026

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Retraction Open Access

[Retracted] DDAH2 alleviates myocardial fibrosis in diabetic cardiomyopathy through activation of the DDAH/ADMA/NOS/NO pathway in rats

Zhen-Dong Zhu, Ji-Ming Ye, Xue-Mei Fu, Xue-Chang Wang, Ji-Yun Ye, Xin-Ran Wu, Peng Hua, Yu-Qiong Liao, Wei Xuan, Jin-Lan Duan, Wei-Yuan Li, Hui Fu, Zhong-Hua Xia, Xuan Zhang
Article Number: 63
Published online on: 19 January 2026

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Review Open Access

Beyond hepatic stellate cell heterogeneity: Resolving fibrosis, restoring regeneration (Review)

Chang Gao, Guiqing Chen, Hongyan Jia, Hong Zhu, Yun Cai, Dakai Yang, Kai Zhao
Article Number: 62
Published online on: 14 January 2026

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Correction Open Access

[Corrigendum] CDKN2A (p16INK4A) affects the anti‑tumor effect of CDK inhibitor in somatotroph adenomas

Yiyuan Chen, Zhenye Li, Qiuyue Fang, Hongyun Wang, Chuzhong Li, Hua Gao, Yazhuo Zhang
Article Number: 61
Published online on: 14 January 2026

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Review Open Access

Harnessing MSC‑derived exosomes to modulate the pathophysiology of ASD: Recent advances and therapeutic implications (Review)

Zhaojian Sun, Nouman Amjad, Majid Muhammad, Zhiyuan Li
Article Number: 60
Published online on: 13 January 2026

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Retraction Open Access

[Retracted] Mechanism of cell death induced by silica nanoparticles in hepatocyte cells is by apoptosis

Ye Yang, Xinjing Du, Qiang Wang, Jianwei Liu, Enguo Zhang, Linlin Sai, Cheng Peng, Martin F. Lavin, Abrey Jie Yeo, Xu Yang, Hua Shao, Zhongjun Du
Article Number: 59
Published online on: 12 January 2026

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Review Open Access

ZG16B: A key regulator of tumor progression and immune microenvironment modulation in cancer (Review)

Xing-Ming Chen, Yu-Bo Liang, Jin-Xiang Zuo, Zi-Sheng Yang, Le-Yu Zhang, Xin-Yu Zhang, Ping Wan, Yang Ke
Article Number: 58
Published online on: 09 January 2026

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Retraction Open Access

[Retracted] Silica nanoparticles induce cardiomyocyte apoptosis via the mitochondrial pathway in rats following intratracheal instillation

Zhongjun Du, Shangya Chen, Guanqun Cui, Ye Yang, Enguo Zhang, Qiang Wang, Martin F. Lavin, Abrey J. Yeo, Cunxiang Bo, Yu Zhang, Chao Li, Xiaoshan Liu, Xu Yang, Cheng Peng, Hua Shao
Article Number: 57
Published online on: 05 January 2026

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Review Open Access

Role of cuproptosis in digestive system tumors (Review)

Li Zhang, Yongpeng Cheng, Lulu Tang, Jiaxing Zhu, Biguang Tuo
Article Number: 56
Published online on: 02 January 2026

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Review Open Access

Environmental exposure to air pollution and climate: Intersecting the impact on ear and nose health and chemosensory function (Review)

Yu-Chen Zhang, Lei Zhang, Ping-Ting Zhou, Zi-Hui Xie, Wen-Jie Zhang, Min Fan, Yan-Xun Han, Ye-Hai Liu, Yu-Chen Liu
Article Number: 55
Published online on: 31 December 2025

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Review Open Access

Role and mechanisms of ferroptosis in cognitive impairment: From molecular pathways to therapeutic targets (Review)

Shenghui Ge, Deyue Kong, Shuyue Fan, Yi Luo, Xiao Yin, Zehua Jin, Wenqing Xia, Jianhua Ma
Article Number: 54
Published online on: 30 December 2025

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Review Open Access

The GPR124‑Wnt‑PPARγ regulatory axis: Molecular mechanisms and therapeutic implications in chronic inflammatory diseases (Review)

Ming-Wang Cui, Si-Yu Tao, Tao Wen, Zhu-Ling Guo
Article Number: 53
Published online on: 30 December 2025

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Review Open Access

Advances in RPGR gene therapy for X‑linked retinitis pigmentosa: From preclinical insights to clinical application (Review)

Yushan Long, Jia Qi, Wenliang Zhang, Huan Qin, Kai Yao
Article Number: 52
Published online on: 30 December 2025

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Journal Cover
April-2026 Volume 57 Issue 4

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Immunological mechanisms and novel therapeutic strategies for sepsis‑associated acute kidney injury (Review)

Lu Xu, Wei Jiang, Lin Song, Jing Wang, Jiangquan Yu, Ruiqiang Zheng
Article Number: 78
Published online on: 30 January 2026

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Correction Open Access

[Corrigendum] Role of Smad3 signaling in the epithelial‑mesenchymal transition of the lens epithelium following injury

Fanlan Meng, Jun Li, Xiao Yang, Xiaoyong Yuan, Xin Tang
Article Number: 77
Published online on: 29 January 2026

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Review Open Access

Spatial metabolomics: A new tool for unravelling the metabolic disorders and heterogeneity in diabetic kidney disease (Review)

Hanfei Li, Yuxi Li, Bo Zhang, Wenhao Cheng, Guowei Ma, Jin Rong, Shiru Duan, Di Feng, Tingting Zhao
Article Number: 76
Published online on: 29 January 2026

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