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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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International Journal of Molecular Medicine

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
February 2013 Volume 31 Issue 2

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Journal Metrics

Impact Factor: 8.5

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

The role of peptide YY in gastrointestinal diseases and disorders (Review)

Magdy El-Salhy, Tarek Mazzawi, Doris Gundersen, Jan Gunnar Hatlebakk, Trygve Hausken
Pages: 275-282
Published online on: 21 December 2012

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Article Open Access

B7-H3 overexpression in pancreatic cancer promotes tumor progression

Xin Zhao, De-Chun Li, Xin-Guo Zhu, Wen-Juan Gan, Zhi Li, Feng Xiong, Zi-Xiang Zhang, Guang-Bo Zhang, Xue-Guang Zhang, Hua Zhao
Pages: 283-291
Published online on: 13 December 2012

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Article

Short-term mechanical stress inhibits osteoclastogenesis via suppression of DC-STAMP in RAW264.7 cells

Sumika Kameyama, Yoshitaka Yoshimura, Takeshi Kameyama, Takashi Kikuiri, Mino Matsuno, Yoshiaki Deyama, Kuniaki Suzuki, Junichiro Iida
Pages: 292-298
Published online on: 21 December 2012

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Article

The potential of recombinant vesicular stomatitis virus-mediated virotherapy against metastatic colon cancer

Minoru Yamaki, Katsunori Shinozaki, Takemasa Sakaguchi, Marcia Meseck, Oliver Ebert, Hideki Ohdan, Savio L.C. Woo
Pages: 299-306
Published online on: 06 December 2012

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Article

Forced mastication increases survival of adult neural stem cells in the hippocampal dentate gyrus

Yuki Akazawa, Takamasa Kitamura, Yuri Fujihara, Yoshitaka Yoshimura, Masato Mitome, Tomokazu Hasegawa
Pages: 307-314
Published online on: 18 December 2012

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Article

CD133 silencing inhibits stemness properties and enhances chemoradiosensitivity in CD133-positive liver cancer stem cells

Xi Lan, Yong-Zhong Wu, Yong Wang, Fu-Rong Wu, Chun‑Bao  Zang, Chuan Tang, Shu Cao, Shao-Lin Li
Pages: 315-324
Published online on: 06 December 2012

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Article

Lactoferrin protects against prion protein-induced cell death in neuronal cells by preventing mitochondrial dysfunction

Yang-Gyu Park, Jae-Kyo Jeong, Ju-Hee Lee, You-Jin Lee, Jae-Won Seol, Shang-Jin Kim, Tai-Young Hur, Young-Hun Jung, Seog-Jin Kang, Sang-Youel Park
Pages: 325-330
Published online on: 29 November 2012

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Article

Kaempferol suppresses lipid accumulation in macrophages through the downregulation of cluster of differentiation 36 and the upregulation of scavenger receptor class B type I and ATP-binding cassette transporters A1 and G1

Xiu-Ying Li, Ling-Xi Kong, Juan Li, Hai-Xia He, Yuan-Da Zhou
Pages: 331-338
Published online on: 05 December 2012

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Article

Synergistic effects of histone deacetylase inhibitor in combination with mTOR inhibitor in the treatment of prostate carcinoma

Paul Thelen, Lisa Krahn, Felix Bremmer, Arne  Strauss, Ralph Brehm, Hagen Loertzer
Pages: 339-346
Published online on: 21 December 2012

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Article

Comparison of three different HCV genotyping methods: Core, NS5B sequence analysis and line probe assay

Qingxian Cai, Zhixin Zhao, Ying Liu, Xiaoqiong Shao, Zhiliang Gao
Pages: 347-352
Published online on: 12 December 2012

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Article

Novel rotundic acid derivatives: Synthesis, structural characterization and in vitro antitumor activity

Yu Chen, Yu-Fang He, Min-Lun Nan, Wen-Yi Sun, Jie Hu, Ai Cui, Fan Li, Fang Wang
Pages: 353-360
Published online on: 06 December 2012

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Article

Anti-metastatic effect of polysaccharide isolated from Colocasia esculenta is exerted through immunostimulation

Hye-Ryung Park, Hyun-Sun Lee, Sun Young Cho, Yoon-Sook Kim, Kwang-Soon Shin
Pages: 361-368
Published online on: 27 December 2012

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Article

Intracellular-delivery of a single-chain antibody against hepatitis B core protein via cell-penetrating peptide inhibits hepatitis B virus replication in vitro

Yunhao Xun, Qingchun Pan, Zhenghao Tang, Xiaohua Chen, Yongsheng Yu, Min Xi, Guoqing Zang
Pages: 369-376
Published online on: 12 December 2012

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Article

Combination of oncolytic adenovirus and endostatin inhibits human retinoblastoma in an in vivo mouse model

Huiping Wang, Fang Wei, Huiming Li, Xunda Ji, Shuxia Li, Xiafang Chen
Pages: 377-385
Published online on: 29 November 2012

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Article

Immune activation and antitumor response of ar-turmerone on P388D1 lymphoblast cell implanted tumors

Donghee Kim, Yongjoon Suh, Hyunsook Lee, Yongkyu Lee
Pages: 386-392
Published online on: 29 November 2012

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Article

Cis-guggulsterone inhibits the IKK/NF-κB pathway, whereas trans-guggulsterone inhibits MAPK/AP-1 in MCF‑7 breast cancer cells: Guggulsterone regulates MMP‑9 expression in an isomer-specific manner

Eun-Mi Noh, Eun Yong Chung, Hyun Jo Youn, Sung Hoo Jung, Hyun Hur, Young-Rae Lee, Jong-Suk Kim
Pages: 393-399
Published online on: 14 December 2012

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Article

Cathepsin L stimulates autophagy and inhibits apoptosis of ox-LDL-induced endothelial cells: Potential role in atherosclerosis

Dang-Heng Wei, Xiao-Ying Jia, Yang-Hui Liu, Feng-Xia Guo, Zhi-Han Tang, Xiao-Hong Li, Zuo Wang, Lu-Shan Liu, Gui-Xue Wang, Zhi-Sheng Jian, Chang-Geng Ruan
Pages: 400-406
Published online on: 03 December 2012

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Article

Direct comparison of the potency of human mesenchymal stem cells derived from amnion tissue, bone marrow and adipose tissue at inducing dermal fibroblast responses to cutaneous wounds

Xiaoyu Liu, Zhe Wang, Rui Wang, Feng Zhao, Ping Shi, Yide Jiang, Xining Pang
Pages: 407-415
Published online on: 30 November 2012

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Article

Co-administration of prostaglandin E1 with somatostatin attenuates acute liver damage after massive hepatectomy in rats via inhibition of inflammatory responses, apoptosis and endoplasmic reticulum stress

Changjun Jia, Chaoliu Dai, Xianmin Bu, Songlin Peng, Feng Xu, Yongqing Xu, Yang Zhao
Pages: 416-422
Published online on: 14 December 2012

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Article

Programmed cell death-1 deficiency results in atrial remodeling in C57BL/6 mice

Guoqiang Fu, Yizhan Cao, Jun Lu, Jun Li, Li Liu, Hongtao Wang, Feifei Su, Qiangsun Zheng
Pages: 423-429
Published online on: 19 December 2012

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Article

Collagen-targeting parathyroid hormone-related peptide promotes collagen binding and in vitro chondrogenesis in bone marrow-derived MSCs

Xiao-Cheng Wu, Bo Huang, Jian Wang, Chang-Qing Li, Yue Zhou
Pages: 430-436
Published online on: 19 December 2012

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Article

Adenosine and inosine exert cytoprotective effects in an in vitro model of liver ischemia-reperfusion injury

Katalin Módis, Domokos Gerő, Rita Stangl, Olivér Rosero, Attila Szijártó, Gábor Lotz, Petra Mohácsik, Petra Szoleczky, Ciro Coletta, Csaba Szabó
Pages: 437-446
Published online on: 04 December 2012

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Article

Platelet-derived growth factor-D induces expression of cyclooxygenase-2 in rat mesangial cells through activation of PI3K/PKB and PKCs

Yu-Kyoung Park, Byeong-Churl Jang, Misun Choi
Pages: 447-452
Published online on: 18 December 2012

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Article

Downregulation of γ-catenin inhibits CML cell growth and potentiates the response of CML cells to imatinib through β-catenin inhibition

Chang-Chun Niu, Chen Zhao, Zhen-Dong Yang, Xiao-Li Zhang, Wei-Ru Wu, Jing Pan, Zhi-Qiang Li, Wei Ding, Zhong Yang, Wei-Ke Si
Pages: 453-458
Published online on: 06 December 2012

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Article

Microarray-based analysis of the gene expression profile in GC-1 spg cells transfected with spermatogenesis associated gene 12

Yiting Lin, Zhiwen Liu, Xuanming Liu, Yunsheng Zhang, Zhuoxian Rong, Dan Li
Pages: 459-466
Published online on: 27 December 2012

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Article

A novel dual oxidase maturation factor 2 gene mutation for congenital hypothyroidism

Ru-Hai Yi, Wen-Bin Zhu, Li-Yong Yang, Lan Lan, Yao Chen, Jin-Fu Zhou, Jing Wang, Yue-Qing Su
Pages: 467-470
Published online on: 24 December 2012

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Article

The effects of exogenous H2O2 on cell death, reactive oxygen species and glutathione levels in calf pulmonary artery and human umbilical vein endothelial cells

Woo Hyun Park
Pages: 471-476
Published online on: 18 December 2012

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Article

Decursin inhibits UVB-induced MMP expression in human dermal fibroblasts via regulation of nuclear factor-κB

Bo-Mi Hwang, Eun-Mi Noh, Jong-Suk Kim, Jeong-Mi Kim, Jin-Ki Hwang, Hye-Kyung Kim, Jae-Seon Kang, Do-Sung Kim, Han-Jung Chae, Yong-Ouk You, Kang-Beom Kwon, Young-Rae Lee
Pages: 477-483
Published online on: 04 December 2012

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Article

Mesenchymal stem cells modified with miR-126 release angiogenic factors and activate Notch ligand Delta-like-4, enhancing ischemic angiogenesis and cell survival

Feng Huang, Xiao Zhu, Xin-Qun Hu, Zhen-Fei Fang, Liang Tang, Xiao-Ling Lu, Sheng-Hua Zhou
Pages: 484-492
Published online on: 03 December 2012

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Article

Inhibitory effects of paeoniflorin on lysophosphatidylcholine-induced inflammatory factor production in human umbilical vein endothelial cells

Jian-Zhe Li, Jian-Hua Wu, Shu-Yi Yu, Qing-Rui Shao, Xiao-Min Dong
Pages: 493-497
Published online on: 13 December 2012

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Journal Cover
October-2026 Volume 58 Issue 4

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Journal Metrics

Impact Factor: 8.5

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Role of adipocytes and their derived extracellular vesicles in the progression, diagnosis and treatment of liver diseases (Review)

Kangrong Li, Muhammad Zubair, Yongmin Yan, Jiahao Xu
Article Number: 293
Published online on: 20 August 2026

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Correction Open Access

[Corrigendum] EBM84 attenuates airway inflammation and mucus hypersecretion in an ovalbumin‑induced murine model of asthma

In Sik Shin, Mee Young Lee, Woo Young Jeon, Na Ra Shin, Chang Seob Seo, Hyekyung Ha
Article Number: 292
Published online on: 20 August 2026

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Review Open Access

Decoding fibroblast activation: Transcriptional networks in hepatic stellate cells and across fibrotic organs (Review)

Denita Charoenthanakitkul, Chaiyaboot Ariyachet
Article Number: 291
Published online on: 20 August 2026

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Review Open Access

Inflammatory bowel disease treatment: Mechanisms to clinical translation (Review)

Siqi Tang, Guoyou Gou, Youjia Liu, Fang Wang, Feihong Shu, Ya Deng, Ting Zhang, Jingyu Xu, Rui Xie
Article Number: 290
Published online on: 18 August 2026

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Review Open Access

Redox biology in PCOS: Biomarkers, mechanistic networks, and targeted interventions (Review)

Yuena Qiu, Xiaojing Guo, Jie An
Article Number: 289
Published online on: 18 August 2026

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Review Open Access

Glucose metabolism in osteoporosis: A potential therapeutic target (Review)

Shengyao Peng, Zhuo Yao, Junzhe Guo, Chi Zhang, Keda Yang, Lin Tao
Article Number: 288
Published online on: 17 August 2026

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Retraction Open Access

[Retracted] Engulfment of platelets delays endothelial cell aging via girdin and its phosphorylation

Yong Lan, Yongjun Li, Dajun Li, Peng Li, Jiyang Wang, Yongpeng Diao, Guodong Ye, Yangfang Li
Article Number: 287
Published online on: 17 August 2026

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Article Open Access

α‑Cyperone targets the PAK1‑JNK/NF‑κB axis to modulate dendritic cells maturation and Th2/Th9 differentiation in an asthma model

Hang Hu, Xing Wang, Linlin Guo, Ziling Zeng, Hongmei Tang, Yun Zhang, Jiayao Duan, Kaijin Wang
Article Number: 286
Published online on: 14 August 2026

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Article Open Access

Early high‑frequency spinal cord stimulation modulates the ROS/p38 MAPK/NF‑κB and CXCL10/CXCR3 pathways to alleviate neuropathic pain and promote spinal cord injury repair

Sitong Su, Tao Liu, Honghui Lei, Yang Yu, Caizhi Ma, Xinglang Wang, Haoyuan Chen, Zebin Huang, Meiling Cheng, Tongtong Qian, Fangyong Wang
Article Number: 285
Published online on: 13 August 2026

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Review Open Access

Shared mechanisms of musculoskeletal dysfunction in type 2 diabetes mellitus: Insights into future therapeutic directions (Review)

Zhenhong He, Hanyu Li, Yuhan Luo, Yingying Yu, Siyu Li, Tao Zhang, Dingsu Bao
Article Number: 284
Published online on: 12 August 2026

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Expression of Concern Open Access

[Expression of Concern] Exogenous spermine attenuates diabetic kidney injury in rats by inhibiting AMPK/mTOR signaling pathway

Xinying Zhang, Li Zhang, Zhe Chen, Siwei Li, Bingbing Che, Ningning Wang, Junting Chen, Changqing Xu, Can Wei
Article Number: 283
Published online on: 12 August 2026

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Article Open Access

G protein‑coupled receptor kinase 4 governs early kidney development via STAT3 and Nhe3a

Linh Anna Trúc Vu, Julian Gerhards, Lars D. Maerz, Martin D. Burkhalter, Melanie Philipp
Article Number: 282
Published online on: 11 August 2026

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Retraction Open Access

[Retracted] Resistant starch prevents tumorigenesis of dimethylhydrazine‑induced colon tumors via regulation of an ER stress‑mediated mitochondrial apoptosis pathway  

Qiuyu Wang, Peng Wang, Zhigang Xiao
Article Number: 281
Published online on: 10 August 2026

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Review Open Access

XBP1 signaling from tumor metabolic stress to myeloid driven immunotherapy resistance (Review)

Ziwei Chen, Jiaqi Wu, Wenxi Liu, Jie Tan, Xiaochun Peng, Yanhua Zhang, Gai Liang
Article Number: 280
Published online on: 05 August 2026

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Review Open Access

Decoding miRNA‑146a: Mechanisms of action in cardiovascular diseases and endocrine metabolic disorders (Review)

Xiu Yang, Pengcheng Li, Hao Zhao
Article Number: 279
Published online on: 05 August 2026

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Review Open Access

Contribution of p38 MAPK in liver fibrosis: An overview of mechanisms, signaling pathways, and therapeutic targets (Review)

Xueqin Yang, Huarong Li, Hao Ye, Ting Wu, Fangyun Xu, Chao Hu, Chunlei Yu, Pian Ye
Article Number: 278
Published online on: 05 August 2026

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Correction Open Access

[Corrigendum] Peroxisome proliferator‑activated receptor α regulates acesulfame‑K‑induced NAFLD via hepatic PLCβ: Foe and friend

Peng-Yao Lin, Jia-Rong Xie, Tian-Chen Qian, Shi-Song Wang, Si-Yi Yu, Wen-Bo Shi, Ying Wang, Lu-Ze Cen, Qing-Jing Zhu, Yi-Yang Zheng, Hui Gao, Rong Fang, Zhao-Xia Xia, Ai-Ming Liu, Lei Xu
Article Number: 277
Published online on: 05 August 2026

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Review Open Access

Multi‑omics insights into uveitis: From mechanisms to precision medicine (Review)

Chengzhi Liu, Qiong Wu, Mingzhen Yuan, Mingyue Liu, Xinyu Wang, Jiaqi Shen, Xusheng Cao
Article Number: 276
Published online on: 03 August 2026

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Retraction Open Access

[Retracted] Effects of miRNA‑455 on cardiac hypertrophy induced by pressure overload

Chuntao Wu, Shimin Dong, Yongjun Li
Article Number: 275
Published online on: 03 August 2026

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Article Open Access

Energy stress activates AMPK to suppress ferroptosis in neurodegenerative proteinopathies

Yuanyuan Yong, Yuxin Hu, Qian Feng, Xiaogang Zhou, Lu Yu, Dalian Qin, Jianing Mi, Jianming Wu, Jianxin Liu, Anguo Wu
Article Number: 274
Published online on: 31 July 2026

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Article Open Access

Brazilin attenuates methylglyoxal‑induced endothelial injury by enhancing eIF5A hypusination and inhibiting the AMPK/mTOR‑mediated autophagy/apoptosis axis in vitro and in vivo

Yu Liang, Jinxiang Chen, Haiyang Li, Junjing Xiong, Jingcan You, Liqun Wang, Jianbo Wu, Youkun Zheng, Mao Luo
Article Number: 273
Published online on: 30 July 2026

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Review Open Access

Post‑translational modifications in atherosclerosis: Roles, mechanisms and therapeutic potential (Review)

Xiaoxiang Xu, Fei Ma, Wei Yu
Article Number: 272
Published online on: 30 July 2026

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Review Open Access

Role of extracellular matrix in liver fibrosis regression and regeneration (Review)

Yuanzhi Zhou, Zeyuan Qiang, Yang Duan, Jiwei Huang, Haichuan Wang
Article Number: 271
Published online on: 29 July 2026

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Correction Open Access

[Corrigendum] Circulating microRNA profiles and the identification of miR‑593 and miR‑511 which directly target the PROP1 gene in children with combined pituitary hormone deficiency

Yanyan Hu, Qian Wang, Zengmin Wang, Fengxue Wang, Xiaobo Guo, Guimei Li
Article Number: 270
Published online on: 29 July 2026

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Review Open Access

Unveiling the role of spatial transcriptomics in the analysis of the tumor immune microenvironment (Review)

Jialin Jiang, Xinyu Tu, Yi Cao, Qun Yan, Buqing Sai, Jian Ma
Article Number: 269
Published online on: 28 July 2026

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Expression of Concern Open Access

[Expression of Concern] Luteolin protects mice from severe acute pancreatitis by exerting HO‑1‑mediated anti‑inflammatory and antioxidant effects

Jie Xiong, Kezhou Wang, Chunxiao Yuan, Rong Xing, Jianbo Ni, Guoyong Hu, Fengling Chen, Xingpeng Wang
Article Number: 268
Published online on: 27 July 2026

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Article Open Access

circRNA_013145‑miR‑185‑5p‑RhoA axis: A novel mechanism in the pathophysiology of diabetes‑induced erectile dysfunction

Wenhan Huang, Xin Lv, Jiahua Qian, Yihao Chen, Yuhe Si, Jingwei Wang, Jianxiong Ma
Article Number: 267
Published online on: 24 July 2026

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Review Open Access

Gut‑liver‑kidney axis: A systems biology framework for understanding and treating chronic kidney disease (Review)

Jinyi Hou, Yaotan Li, Shijia Lin, Qingqing Liu, Huijuan Zheng, Weijing Liu, Yaoxian Wang, Liang Peng, Zhen Wang
Article Number: 266
Published online on: 23 July 2026

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Review Open Access

Effects of cuproptosis and its application in inflammatory bowel disease (Review)

Li Chen, Francis Atim Akanyibah, Jing Guan, Bing Pei, Bo Wang, Fei Mao
Article Number: 265
Published online on: 23 July 2026

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November-2026 Volume 58 Issue 5

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Impact Factor: 8.5

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Breaking the cycle of fibrosis: Ferroptosis as a therapeutic target (Review)

Xincheng Feng, Jue Zhang, Qinghong Ma, Chao Sun
Article Number: 298
Published online on: 27 August 2026

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Correction Open Access

[Corrigendum] Tumor‑targeting novel manganese complex induces ROS‑mediated apoptotic and autophagic cancer cell death

Jia Liu, Wenjie Guo, Jing Li, Xiang Li, Ji Geng, Qiuyun Chen, Jing Gao
Article Number: 297
Published online on: 26 August 2026

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Review Open Access

Advances in sirtuin research in lung diseases (Review)

Shuangyun Xi, Weijun Chen, Xiuli Li, Yudan Wang, Yong Ke
Article Number: 296
Published online on: 25 August 2026

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Article Open Access

lncRNA TUG1 mediates palmitic acid‑induced neuronal lipotoxic injury via the miR‑449a‑5p/caspase‑3 and Akt/GSK‑3β axes

Ya-Dong Wei, Peng-Quan Chen, Xin Zheng, Le-Qi Wu, Xin-Yi Wang, Xin-Ran Gao, Jin-Fang Ge
Article Number: 295
Published online on: 25 August 2026

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Retraction Open Access

[Retracted] Downregulation of LINC00707 promotes osteogenic differentiation of human bone marrow‑derived mesenchymal stem cells by regulating DKK1 via targeting miR‑103a‑3p

Jun Liu, Minfei Wu, Guang Feng, Rui Li, Yang Wang, Jianhang Jiao
Article Number: 294
Published online on: 24 August 2026

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