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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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March-2019 Volume 41 Issue 3

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

Predicting resistance to endocrine therapy in breast cancer: It's time for epigenetic biomarkers (Review)

Mário Fontes‑Sousa, Maria Amorim, Sofia Salta, Susana Palma De Sousa, Rui Henrique, Carmen Jerónimo
Pages: 1431-1438
Published online on: 11 January 2019

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Review

MicroRNAs and the PTEN/PI3K/Akt pathway in gastric cancer (Review)

Mingli Hu, Shixuan Zhu, Shengwei Xiong, Xingxing Xue, Xiaodong Zhou
Pages: 1439-1454
Published online on: 10 January 2019

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Review

Ubiquitination‑deubiquitination in the Hippo signaling pathway (Review)

Yanting Liu, Jun Deng
Pages: 1455-1475
Published online on: 08 January 2019

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Article Open Access

Chitosan-coated liposomes loaded with butyric acid demonstrate anticancer and anti-inflammatory activity in human hepatoma HepG2 cells

Vincenzo Quagliariello, Mario Masarone, Emilia Armenia, Aldo Giudice, Manlio Barbarisi, Michele Caraglia, Alfonso Barbarisi, Marcello Persico
Pages: 1476-1486
Published online on: 13 December 2018

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Article Open Access

Bromodomain‑containing protein 7 sensitizes breast cancer cells to paclitaxel by activating Bcl2‑antagonist/killer protein

Jinqi Ma, Weihong Niu, Xinye Wang, Yao Zhou, Heran Wang, Fengxia Liu, Yukun Liu, Jie Guo, Wei Xiong, Zhaoyang Zeng, Songqing Fan, Xiaoling Li, Xinmin Nie, Guiyuan Li, Rong Gui, Yanwei Luo, Ming Zhou
Pages: 1487-1496
Published online on: 21 December 2018

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Article Open Access

MicroRNA‑200a suppresses migration and invasion and enhances the radiosensitivity of NSCLC cells by inhibiting the HGF/c‑Met signaling pathway

Menghua Du, Jin Wang, Huan Chen, Shouli Wang, Liesong Chen, Yichang Xu, Fengtao Su, Xueguan Lu
Pages: 1497-1508
Published online on: 12 December 2018

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Article Open Access

SOCS4 expressed by recombinant HSV protects against cytokine storm in a mouse model

Shuqi Ren, Xiaoqing Chen, Rongquan Huang, Grace Guoying Zhou, Zhuqing Yuan
Pages: 1509-1520
Published online on: 18 December 2018

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Article Open Access

A 6‑gene risk score system constructed for predicting the clinical prognosis of pancreatic adenocarcinoma patients

Yan Liu, Dongyan Zhu, Hongjian Xing, Yi Hou, Yan Sun
Pages: 1521-1530
Published online on: 22 January 2019

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Article Open Access

CTHRC1 overexpression promotes cervical carcinoma progression by activating the Wnt/PCP signaling pathway

Mei Zheng, Qin Zhou, Xingguang Liu, Chengze Wang, Gangli Liu
Pages: 1531-1538
Published online on: 10 January 2019

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Article Open Access

Peroxiredoxin2 downregulation enhances hepatocellular carcinoma proliferation and migration, and is associated with unfavorable prognosis in patients

Bing Bai, Yanyan Lin, Jinjing Hu, Haiping Wang, Lu Li, Sheng Zhao, Jinduo Zhang, Wenbo Meng, Ping Yue, Zhongtian Bai, Xun  Li
Pages: 1539-1548
Published online on: 22 January 2019

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Article Open Access

miRNA-223 is an anticancer gene in human non-small cell lung cancer through the PI3K/AKT pathway by targeting EGFR

Hui-Ping Ma, Wei-Xiang Kong, Xiu-Ying Li, Wei Li, Yan Zhang, Yan Wu
Pages: 1549-1559
Published online on: 24 January 2019

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Article Open Access

Pilot investigation of the mutation profile of PIK3CA/PTEN genes (PI3K pathway) in grade 3 endometrial cancer

Francesca Malentacchi, Irene Turrini, Flavia Sorbi, Elisabetta Projetto, Francesca Castiglione, Massimiliano Fambrini, Felice Petraglia, Serena Pillozzi, Ivo Noci
Pages: 1560-1574
Published online on: 18 December 2018

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Article Open Access

miR‑107‑5p promotes tumor proliferation and invasion by targeting estrogen receptor‑α in endometrial carcinoma

Wei Bao, Yan Zhang, Shuangdi Li, Qiong Fan, Meiting Qiu, Yanan Wang, Yanli Li, Xiaoning Ji, Ye Yang, Zhenyu Sang, Wei Xu, Yongbin Yang, Sufang Wu, Yaping Zhu
Pages: 1575-1585
Published online on: 18 December 2018

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Article Open Access

Identification of prognostic biomarkers for patients with hepatocellular carcinoma after hepatectomy

Xiangkun Wang, Xiwen Liao, Chengkun Yang, Ketuan Huang, Tingdong Yu, Long Yu, Chuangye Han, Guangzhi Zhu, Xianmin Zeng, Zhengqian Liu, Xin Zhou, Wei Qin, Hao Su, Xinping Ye, Tao Peng
Pages: 1586-1602
Published online on: 03 January 2019

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Article Open Access

ERp29 counteracts the suppression of malignancy mediated by endoplasmic reticulum stress and promotes the metastasis of colorectal cancer

Lili Guo, Lili Ma, Chao Liu, Yan Lei, Na Tang, Yingxin Huang, Guan Huang, Dazhou Li, Qi Wang, Guanglong Liu, Minshan Tang, Zhiliang Jing, Yongjian Deng
Pages: 1603-1615
Published online on: 19 December 2018

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Article Open Access

Imatinib‑induced apoptosis of gastric cancer cells is mediated by endoplasmic reticulum stress

Jung Lim Kim, Dae‑Hee Lee, Soyeon Jeong, Bo Ram Kim, Yoo Jin Na, Seong Hye Park, Min Jee Jo, Yoon A. Jeong, Sang Cheul Oh
Pages: 1616-1626
Published online on: 19 December 2018

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Article Open Access

MicroRNA‑21 regulates the biological behavior of esophageal squamous cell carcinoma by targeting RASA1

Xiaohua Chen, Sina Cai, Baoxia Li, Xiaona Zhang, Wenhui Li, Henglun Liang, Xiaolong Cao, Liping Wang, Ziqing Wu
Pages: 1627-1637
Published online on: 19 December 2018

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Article Open Access

miR‑498 inhibits the growth and metastasis of liver cancer by targeting ZEB2

Xu Zhang, Xueying Xu, Guohong Ge, Xueyan Zang, Meng Shao, Shengqiang Zou, Yu Zhang, Zheying Mao, Jiayin Zhang, Fei Mao, Hui Qian, Wenrong Xu
Pages: 1638-1648
Published online on: 21 December 2018

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Article Open Access

SHCBP1 is a novel target and exhibits tumor‑promoting effects in gastric cancer

Ya‑Dong Dong, Yan‑Li Yuan, Hai‑Bo Yu, Guang‑Jin Tian, De‑Yu Li
Pages: 1649-1657
Published online on: 21 December 2018

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Article Open Access

Electrochemotherapy of radioresistant head and neck squamous cell carcinoma cells and tumor xenografts

Martina Niksic Zakelj, Ajda Prevc, Simona Kranjc, Maja Cemazar, Vesna Todorovic, Monika Savarin, Janez Scancar, Tina Kosjek, Blaz Groselj, Primoz Strojan, Gregor Sersa
Pages: 1658-1668
Published online on: 09 January 2019

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Article Open Access

MicroRNA‑3653 inhibits the growth and metastasis of hepatocellular carcinoma by inhibiting ITGB1

Lijuan Zhang, Tao Zhang, Zerun Deng, Lihua Sun
Pages: 1669-1677
Published online on: 16 January 2019

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Article Open Access

The PI3K/AKT signaling pathway regulates ABCG2 expression and confers resistance to chemotherapy in human multiple myeloma

Lei Wang, Na Lin, Yan Li
Pages: 1678-1690
Published online on: 11 January 2019

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Article Open Access

Downregulation of PRMT1, a histone arginine methyltransferase, by sodium propionate induces cell apoptosis in colon cancer

Tae Young Ryu, Kwangkho Kim, Mi-Young Son, Jeong-Ki Min, Janghwan Kim, Tae-Su Han, Dae-Soo Kim, Hyun-Soo Cho
Pages: 1691-1699
Published online on: 18 December 2018

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Article Open Access

Gambogenic acid inhibits the proliferation of small‑cell lung cancer cells by arresting the cell cycle and inducing apoptosis

Tingting Huang, Hongming Zhang, Xiyong Wang, Lu Xu, Jinfang Jia, Xiaoli Zhu
Pages: 1700-1706
Published online on: 21 December 2018

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Article Open Access

miR‑29a ameliorates ischemic injury of astrocytes in vitro by targeting the water channel protein aquaporin 4

Yueying Zheng, Caifei Pan, Manli Chen, Aijie Pei, Liwei Xie, Shengmei Zhu
Pages: 1707-1717
Published online on: 09 January 2019

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Article Open Access

miR663a‑TTC22V1 axis inhibits colon cancer metastasis

Wei Tian, Yantao Du, Yuwan Ma, Baozhen Zhang, Liankun Gu, Jing Zhou, Dajun Deng
Pages: 1718-1728
Published online on: 16 January 2019

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Article

Integrating modern approaches to pathogenetic concepts of malignant transformation of endometriosis

Hiroshi Kobayashi, Yuki Yamada, Naoki Kawahara, Kenji Ogawa, Chiharu Yoshimoto
Pages: 1729-1738
Published online on: 21 December 2018

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Article

Upregulation of USP11 promotes epithelial‑to‑mesenchymal transition by deubiquitinating Snail in ovarian cancer

Weiwei Wang, Jing Wang, Hua Yan, Kai Zhang, Yang Liu
Pages: 1739-1748
Published online on: 12 December 2018

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Article

Wnt7a predicts poor prognosis, and contributes to growth and metastasis in tongue squamous cell carcinoma

Bo Jia, Xiaoling Qiu, Hongxing Chu, Xiang Sun, Shuaimei Xu, Xinyuan Zhao, Jianjiang Zhao
Pages: 1749-1758
Published online on: 22 January 2019

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Article

The HIF‑1α/miR‑224‑3p/ATG5 axis affects cell mobility and chemosensitivity by regulating hypoxia‑induced protective autophagy in glioblastoma and astrocytoma

Sihua Huang, Peng Qi, Ting Zhang, Fengtao Li, Xijing He
Pages: 1759-1768
Published online on: 13 December 2018

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Article

Distinctive clinicopathological features and disease‑specific survival of adenoid cystic carcinoma and adenoid basal carcinoma in the lower female genital tract

Deyin Xing, Jiayun Lu
Pages: 1769-1778
Published online on: 12 December 2018

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Article

Gallic acid has anticancer activity and enhances the anticancer effects of cisplatin in non‑small cell lung cancer A549 cells via the JAK/STAT3 signaling pathway

Tingxiu Zhang, Lijie Ma, Pengfei Wu, Wei Li, Ting Li, Rui Gu, Xiaoping Dan, Zhiwei Li, Xianming Fan, Zhenliang Xiao
Pages: 1779-1788
Published online on: 22 January 2019

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Article

Downregulated Krüppel‑like factor 4 expression is associated with the aggressiveness of prostate cancer

Neng Zhang, Peng Su, Xiaoguang Li, Jianming Xi, Xu Li, Luo Xu
Pages: 1789-1796
Published online on: 22 January 2019

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Article

lncRNA CASC2/miR‑18a‑5p axis regulates the malignant potential of nasopharyngeal carcinoma by targeting RBBP8

Wen‑Jie Miao, Dong‑Jie Yuan, Guo‑Zheng Zhang, Qi Liu, Hui‑Min Ma, Qian‑Qian Jin
Pages: 1797-1806
Published online on: 19 December 2018

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Article

Cytoplasmic M‑CSF facilitates apoptosis resistance by inhibiting the HIF‑1α/BNIP3/Bax signalling pathway in MCF‑7 cells

Mengxia Zhang, Qi Liu, Lijun Li, Jing Ning, Jian Tu, Xiaoyong Lei, Zhongcheng Mo, Shengsong Tang
Pages: 1807-1816
Published online on: 21 December 2018

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Article

Effect of NELL1 on lung cancer stem‑like cell differentiation

Yuanfen Zhai, Rongbin Wei, Shuang Sha, Chengzhao  Lin, Heyong Wang, Xinquan Jiang, Gentao Liu
Pages: 1817-1826
Published online on: 03 January 2019

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Article

PTEN downregulates WD repeat‑containing protein 66 in salivary adenoid cystic carcinoma

Yu Cao, Han Liu, Shi‑Lin Xia, Xi Zhang, Han Bai, Qian Yang, Jiang Li, Liwei Gao, Feng Jin, Min‑Jie Wei, Shi‑Long Lu, Jing Xiao
Pages: 1827-1836
Published online on: 13 December 2018

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Article

Kenalog modified by ionizing radiation induces intrinsic apoptosis mediated by elevated levels of reactive oxygen species in melanoma cancer

Remigius Ambrose Kawala, Fatuma Jumapili Ramadhani, Hyo Jin Choi, Eun‑Hee Lee, Chul‑Hong Park, Byung Yeoup Chung, Hyoung‑Woo Bai
Pages: 1837-1850
Published online on: 19 December 2018

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Article

Biological characterisation and application of human MTH1 and monoclonal antibody preparation

Chuyuan Chen, Xiaoping Li, Mengyue Gu, Rongrong Di, Nannan Kang, Lei Wang, Yisheng Lai, Yu Liu, Xuemei Ji
Pages: 1851-1862
Published online on: 19 December 2018

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Article

Intravesical treatment of chemotherapeutic agents sensitizes bacillus Calmette‑Guerin by the modulation of the tumor immune environment

Shunta Hori, Makito Miyake, Yoshihiro Tatsumi, Yosuke Morizawa, Yasushi Nakai, Sayuri Onishi, Kenta Onishi, Kota Iida, Daisuke Gotoh, Yoshitaka Itami, Nobumichi Tanaka, Kiyohide Fujimoto
Pages: 1863-1874
Published online on: 10 January 2019

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Article

XPC inhibition rescues cisplatin resistance via the Akt/mTOR signaling pathway in A549/DDP lung adenocarcinoma cells

Xue Teng, Xiao‑Fan Fan, Qi Li, Shuang Liu, Dong‑Yuan Wu, Shu‑Ya Wang, Yuanqi Shi, Mei Dong
Pages: 1875-1882
Published online on: 09 January 2019

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Article

Momelotinib sensitizes glioblastoma cells to temozolomide by enhancement of autophagy via JAK2/STAT3 inhibition

Tie Liu, Anqi Li, Yulun Xu, Yu Xin
Pages: 1883-1892
Published online on: 16 January 2019

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Article

Expression profiles and potential functions of circular RNAs in extracellular vesicles isolated from radioresistant glioma cells

Mengjie Zhao, Jinjin Xu, Shanliang Zhong, Yuchi Liu, Hong Xiao, Liangyuan Geng, Hongyi Liu
Pages: 1893-1900
Published online on: 18 January 2019

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Article

Downregulation of BAG‑1 in T47D cells promotes resistance to tamoxifen via activation of the PI3K/Akt/mTOR signaling pathway

Su Lu, Yiyi Du, Fang Cui, Xinyi Feng, Yuanyuan Ma, Hong Liu
Pages: 1901-1910
Published online on: 22 January 2019

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Article

CX3CL1 promotes lung cancer cell migration and invasion via the Src/focal adhesion kinase signaling pathway

Wangmi Liu, Yun Liang, Qian Chan, Libo Jiang, Jian Dong
Pages: 1911-1917
Published online on: 09 January 2019

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Article

Interaction between C2ORF68 and HuR in human colorectal cancer

Zhaoxu Lv, Kunyan He, Lihong Shi, Kai Shi, Tingting Jiang, Yao Chen
Pages: 1918-1928
Published online on: 21 January 2019

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Article

Identification and validation of alternative splicing isoforms as novel biomarker candidates in hepatocellular carcinoma

Peng Wu, Donghu Zhou, Yuqian Wang, Weiran Lin, Aihua Sun, Handong Wei, Yi Fang, Xianling Cong, Ying Jiang
Pages: 1929-1937
Published online on: 21 December 2018

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Article

MicroRNA‑486‑5p functions as a tumor suppressor of proliferation and cancer stem‑like cell properties by targeting Sirt1 in liver cancer

Xinlong Yan, Xinhui Liu, Zhaohai Wang, Qian Cheng, Guanghong Ji, Hui Yang, Lingfei Wan, Chen Ge, Quan Zeng, Hua Huang, Jiafei Xi, Lijuan He, Xue Nan, Wen Yue, Xuetao Pei
Pages: 1938-1948
Published online on: 13 December 2018

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Article

PEA‑15 contributes to the clinicopathology and AKT‑regulated cisplatin resistance in gastric cancer

Xian Jiang, Changlu Zhang, Weidong Li, Dalei Jiang, Zheng Wei, Mei Lv, Xiangjun Xie, Xueying Sun
Pages: 1949-1959
Published online on: 18 December 2018

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Article

Radiosensitization of esophageal carcinoma cells by knockdown of HMGB1 expression

Xueyuan Zhang, Xingxiao Yang, Shuchai Zhu, Qiaofang Li, Naiyi Zou
Pages: 1960-1970
Published online on: 10 December 2018

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Article

Inhibition of PIKfyve using YM201636 suppresses the growth of liver cancer via the induction of autophagy

Jiu‑Zhou Hou, Zhuo‑Qing Xi, Jie Niu, Wei Li, Xiao Wang, Chao Liang, Hua Sun, Dong Fang, Song‑Qiang Xie
Pages: 1971-1979
Published online on: 12 December 2018

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Article

The role of ZBTB38 in promoting migration and invasive growth of bladder cancer cells

Jingchen Jing, Jie Liu, Yaochun Wang, Miao Zhang, Lu Yang, Feiyu Shi, Peijun Liu, Junjun She
Pages: 1980-1990
Published online on: 18 December 2018

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Article

Combined inhibition of sonic Hedgehog signaling and histone deacetylase is an effective treatment for liver cancer

Jingmin Li, Heng Cai, Hongxing Li, Yanguo Liu, Yirong Wang, Yan Shi, Yan Sun, Haoran Song, Dong Wang
Pages: 1991-1997
Published online on: 23 January 2019

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Article

Stanniocalcin‑1 promotes cell proliferation, chemoresistance and metastasis in hypoxic gastric cancer cells via Bcl‑2

Yan Wang, Zihao Qi, Menglong Zhou, Wang Yang, Ran Hu, Guichao Li, Xuejun Ma, Zhen Zhang
Pages: 1998-2008
Published online on: 23 January 2019

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Article

17β‑hydroxysteroid dehydrogenase 4 induces liver cancer proliferation‑associated genes via STAT3 activation

Xin Lu, Lingyu Kong, Xi Wang, Weiran Liu, Panpan Ma, Lingling Jiang
Pages: 2009-2019
Published online on: 23 January 2019

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Article

Shikonin induces an anti‑tumor effect on murine mammary cancer via p38‑dependent apoptosis

Jiuxiang Xu, Keiichi Koizumi, Mengxin Liu, Yusuke Mizuno, Mikiko Suzaki, Hirofumi Iitsuka, Akiko Inujima, Makoto Fujimoto, Naotoshi Shibahara, Yutaka Shimada
Pages: 2020-2026
Published online on: 11 January 2019

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Article

Disruption of MAPK1 expression in the ERK signalling pathway and the RUNX1‑RUNX1T1 fusion gene attenuate the differentiation and proliferation and induces the growth arrest in t(8;21) leukaemia cells

Salem Ali Al‑Salem Bashanfer, Mohamed Saleem, Olaf Heidenreich, Emmanuel Jairaj Moses, Narazah Mohd Yusoff
Pages: 2027-2040
Published online on: 12 December 2018

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Article

Early decrease in serum amphiregulin or vascular endothelial growth factor levels predicts sorafenib efficacy in hepatocellular carcinoma

Corinne Godin, Sandra Bodeau, Zuzana Saidak, Christophe Louandre, Catherine François, Jean‑Claude Barbare, Romain Coriat, Antoine Galmiche, Chloé Sauzay
Pages: 2041-2050
Published online on: 10 December 2018

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Article

Introduction of exogenous wild‑type p53 mediates the regulation of oncoprotein 18/stathmin signaling via nuclear factor‑κB in non‑small cell lung cancer NCI‑H1299 cells

Sangyan Chen, Yan Zhao, Fang Shen, Dan Long, Ting Yu, Xuechi Lin
Pages: 2051-2059
Published online on: 10 January 2019

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Anticancer effects of methotrexate in combination with α‑tocopherol and α‑tocopherol succinate on triple‑negative breast cancer

Chyou‑Wei Wei, Yung‑Luen Yu, Yu‑Hsun Chen, Yu‑Ting Hung, Giou‑Teng Yiang
Pages: 2060-2066
Published online on: 09 January 2019

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[Corrigendum] High expression of RELM-α correlates with poor prognosis and promotes angiogenesis in gastric cancer

Ping Chen, Deshou Zhao, Weiyi Wang, Yongping Zhang, Yaozong Yuan, Lifu Wang, Yunlin Wu
Pages: 2067-2067
Published online on: 17 December 2018

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Correction Open Access

[Corrigendum] Oncogenic function of Plac1 on the proliferation and metastasis in hepatocellular carcinoma cells

Yuan Wu, Xiaocong Lin, Xiaoqing Di, Yonghua Chen, Hanning Zhao, Xin Wang
Pages: 2068-2068
Published online on: 04 January 2019

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Journal Cover
January-2026 Volume 55 Issue 1

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Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Harnessing ferroptosis for cancer therapy: Mechanisms and therapeutic strategies (Review)

Nabil Mouawad, Nour El Jaafari, Mirvat El Sibai, Ralph J. Abi-Habib
Article Number: 24
Published online on: 24 November 2025

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Expression of Concern Open Access

[Expression of Concern] Promoter methylation of death‑associated protein kinase and its role in irradiation response in cervical cancer

Rebecca Ching-Yu Leung, Stephanie Si Liu, Kelvin Yuen-Kwong Chan, Kar-Fai Tam, Kar-Loen Chan, Ling-Chui Wong, Hextan Yuen-Sheung Ngan
Article Number: 23
Published online on: 24 November 2025

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Oxaliplatin resistance in pancreatic ductal adenocarcinoma is non‑significantly mediated by diminished drug uptake but is highly linked to a poor apoptotic response to the cytotoxic threat

Hellen Röttgen, Lana Theurer, Teresa Peccerella, Ketaki Sandu, Johanna Weiss, Jürgen Burhenne, John P. Neoptolemos, Beate Köberle, Dirk Theile
Article Number: 22
Published online on: 19 November 2025

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[Corrigendum] Src homology phosphotyrosyl phosphatase 2 mediates cisplatin‑related drug resistance by inhibiting apoptosis and activating the Ras/PI3K/Akt1/survivin pathway in lung cancer cells

Chunlan Tang, Hu Luo, Dan Luo, Heping Yang, Xiangdong Zhou
Article Number: 21
Published online on: 19 November 2025

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S100B drives glioblastoma invasion and migration through TGF‑β2‑mediated epithelial‑mesenchymal transition

Xuemei Liao, Yuan Xu, Honghong Zhou, Qin Yi, Shifang Dong, Bin Tan
Article Number: 20
Published online on: 19 November 2025

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Role of the SOX family in non‑small cell lung cancer: Molecular mechanisms and therapeutic implications (Review)

Kaiwei Wang, Yaoqi Li, Zhening Guo, Lin Song, Xiaoliang Ding, Linsheng Liu, Tao Hu, Yicong Bian, Chenrong Huang, Liyan Miao
Article Number: 19
Published online on: 18 November 2025

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[Retracted] MicroRNA‑18a enhances the radiosensitivity of cervical cancer cells by promoting radiation‑induced apoptosis

Sha Liu, Xiaofen Pan, Qin Yang, Lu Wen, Yao Jiang, Yingchao Zhao, Guiling Li
Article Number: 18
Published online on: 17 November 2025

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Role of histone deacetylases in blood cancer: Exploring peptide‑based inhibitors as therapeutic strategies for leukemia treatment (Review)

Yaneenart Suwanwong, Phornthip Ploensil
Article Number: 17
Published online on: 14 November 2025

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The multidimensional regulatory network of the PD‑1/PD‑L1 axis in the esophageal squamous cell carcinoma microenvironment: Implications for novel combination therapies and precision immunotherapy (Review)

Haoyue Lai, Lu Qi, Zhixuan Lin, Zhongwen Li
Article Number: 16
Published online on: 13 November 2025

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From modification to malignancy: Bridging acetylation mechanisms and therapeutic innovations in melanoma (Review)

Jingwen Wu, Xuxia Cai, Zimo Zhu, Xiahong Li, Kaoyuan Zhang, Chenchen Wu, Bo Yu, Cong Huang
Article Number: 15
Published online on: 12 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑92b promotes tumor growth and activation of NF‑κB signaling via regulation of NLK in oral squamous cell carcinoma

Zhiming Liu, Cynthia Diep, Tiantian Mao, Li Huang, Robert Merrill, Zhouwen Zhang, Youjian Peng
Article Number: 14
Published online on: 11 November 2025

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Article Open Access

C‑terminal HSP90 inhibitor NCT‑58 impairs the cancer stem‑like phenotype and enhances chemotherapy efficacy in TNBC

Eunsun Jung, Yoon-Jae Kim, Kyoungmin Lee, Seojin Jang, Soeun Park, Eunhye Oh, Minsu Park, Seongjae Kim, Dongmi Ko, Yong Koo Kang, Kee Dal Nam, Lee Farrand, Cong-Truong Nguyen, Minh Thanh La, Jihyae Ann, Jeewoo Lee, Ji Young Kim, Jae Hong Seo
Article Number: 13
Published online on: 11 November 2025

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Correction Open Access

[Corrigendum] Compound 225# inhibits the proliferation of human colorectal cancer cells by promoting cell cycle arrest and apoptosis induction

Xiaoxue Zhang, Liujun He, Yong Li, Yifei Qiu, Wujing Hu, Wanying Lu, Huihui Du, Donglin Yang
Article Number: 12
Published online on: 06 November 2025

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Immune system, inflammatory response, and regulated cell death in breast cancer research (Review)

Guangyao Li, Binghui Jin, Jialin Zhou, Shifeng Fang, Zhe Fan
Article Number: 11
Published online on: 05 November 2025

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Retraction Open Access

[Retracted] Uvangoletin induces mitochondria‑mediated apoptosis in HL‑60 cells in vitro and in vivo without adverse reactions of myelosuppression, leucopenia and gastrointestinal tract disturbances

Zhuanzhen Zheng, Zhenhua Qiao, Rong Gong, Yalin Wang, Yiqun Zhang, Yanping Ma, Li Zhang, Yujin Lu, Bo Jiang, Guoxia Li, Chunxia Dong, Wenliang Chen
Article Number: 10
Published online on: 03 November 2025

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Characterization of the anticancer effect of mebendazole and its interaction with standard cytotoxic drugs in patient tumor cells ex vivo and in an in vivo mouse model

Sharmineh Mansoori, Kristin Blom, Claes Andersson, Mårten Fryknäs, Rolf Larsson, Peter Nygren
Article Number: 9
Published online on: 31 October 2025

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Correction Open Access

[Corrigendum] Gemcitabine combined with an engineered oncolytic vaccinia virus exhibits a synergistic suppressive effect on the tumor growth of pancreatic cancer

Wanyuan Chen, Weimin Fan, Guoqing Ru, Fang Huang, Xiaming Lu, Xin Zhang, Xiaozhou Mou, Shibing Wang
Article Number: 8
Published online on: 30 October 2025

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CD44 knockdown and TGF‑β inhibition modulate cell proliferation and invasion in claudin‑low breast cancer cells

Ryoichi Matsunuma, Kazuo Kinoshita, Sae Imada, Shoko Sato, Ryosuke Hayami, Michiko Tsuneizumi
Article Number: 7
Published online on: 30 October 2025

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Retraction Open Access

[Retracted] MicroRNA‑302a targets GAB2 to suppress cell proliferation, migration and invasion of glioma

Jiuhong Ma, Jia Yu, Jingmei Liu, Xing Yang, Miao Lou, Jinghui Liu, Fuqiang Feng, Peigang Ji, Liang Wang
Article Number: 6
Published online on: 27 October 2025

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LRRC59 inhibits perk pathway‑induced apoptosis and promotes cell proliferation, migration and invasion in colorectal cancer cells

Xingdong Hou, Yuting Wang, Yuzhuo Chen, Peiyan Zhong, Guangzhi Wang, Baicheng Li, Bowei Lu, Hanyu Jiang, Shili Ning
Article Number: 5
Published online on: 23 October 2025

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Comparative analysis of the efficacy and safety of antibody‑drug conjugates, radionuclide‑drug conjugates and their combination targeting claudin 18.2 in gastric cancer treatment

Huan Du, Xiao-Fei Hao, Bin-Wei Lin, Yu Zhang, Luo Rui, Jing Wang, Ming-Ming Tang, De-Cai Wang, Yi-Han Zhu, Jie Li, Tang-Zhi Dai, Yuchuan Yang, Xia Yang, Xiaobo Du
Article Number: 4
Published online on: 22 October 2025

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Expression of Concern Open Access

[Expression of Concern] CDKN3 is an independent prognostic factor and promotes ovarian carcinoma cell proliferation in ovarian cancer

Tianren Li, Hui Xue, Yi Guo, Kejun Guo
Article Number: 3
Published online on: 16 October 2025

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Platelet‑circulating tumor cell crosstalk: A pivotal target in cancer diagnosis and therapy (Review)

Lifang Zhang, Ye Yuan, Yan Deng, Lin Wang, Fenghua Chen
Article Number: 2
Published online on: 15 October 2025

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Expression of Concern Open Access

[Expression of Concern] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 1
Published online on: 14 October 2025

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Journal Cover
February-2026 Volume 55 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Alternative splicing in cancer drug resistance: Mechanisms and therapeutic prospects (Review)

Wenpu Zhu, Zikun Wu, Chai Luv, Banghe Bao, Weijie Zhao, Guanglong Chen, Hang Yang, Huihan Ai, Faqiang Liu, Zhi Li
Article Number: 31
Published online on: 05 December 2025

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Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells

Liangliang Jin, Li Wei, Junrui Hua, Rong Zhang, Jiaxin Chen, Jinpeng He, Yanli Yang
Article Number: 30
Published online on: 04 December 2025

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Beyond eradication: Therapeutic reprogramming strategies for cancer normalization (Review)

Aliasgar Shahiwala
Article Number: 29
Published online on: 04 December 2025

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Article Open Access

Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy

Rui Zheng, Yusi Liu, Sen Zhou, Guimei Liu, Xiaobin Liu, Yiyuan Yang, Yufu Zhang
Article Number: 28
Published online on: 04 December 2025

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[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Article Number: 27
Published online on: 04 December 2025

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Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma

Yuto Kitano, Tomoharu Miyashita, Takeo Shimasaki, Isamu Makino, Yoshio Endo, Yasuhiko Yamamoto, Noriyuki Inaki, Shintaro Yagi
Article Number: 26
Published online on: 03 December 2025

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[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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