Journal Articles
Review
Predicting resistance to endocrine therapy in breast cancer: It's time for epigenetic biomarkers (Review)
Mário Fontes‑Sousa, Maria Amorim, Sofia Salta, Susana Palma De Sousa, Rui Henrique, Carmen Jerónimo
Pages: 1431-1438 Published online on: 11 January 2019
Review
MicroRNAs and the PTEN/PI3K/Akt pathway in gastric cancer (Review)
Mingli Hu, Shixuan Zhu, Shengwei Xiong, Xingxing Xue, Xiaodong Zhou
Pages: 1439-1454 Published online on: 10 January 2019
Review
Ubiquitination‑deubiquitination in the Hippo signaling pathway (Review)
Yanting Liu, Jun Deng
Pages: 1455-1475 Published online on: 08 January 2019
Article
Chitosan-coated liposomes loaded with butyric acid demonstrate anticancer and anti-inflammatory activity in human hepatoma HepG2 cells
Vincenzo Quagliariello, Mario Masarone, Emilia Armenia, Aldo Giudice, Manlio Barbarisi, Michele Caraglia, Alfonso Barbarisi, Marcello Persico
Pages: 1476-1486 Published online on: 13 December 2018
Article
Bromodomain‑containing protein 7 sensitizes breast cancer cells to paclitaxel by activating Bcl2‑antagonist/killer protein
Jinqi Ma, Weihong Niu, Xinye Wang, Yao Zhou, Heran Wang, Fengxia Liu, Yukun Liu, Jie Guo, Wei Xiong, Zhaoyang Zeng, Songqing Fan, Xiaoling Li, Xinmin Nie, Guiyuan Li, Rong Gui, Yanwei Luo, Ming Zhou
Pages: 1487-1496 Published online on: 21 December 2018
Article
MicroRNA‑200a suppresses migration and invasion and enhances the radiosensitivity of NSCLC cells by inhibiting the HGF/c‑Met signaling pathway
Menghua Du, Jin Wang, Huan Chen, Shouli Wang, Liesong Chen, Yichang Xu, Fengtao Su, Xueguan Lu
Pages: 1497-1508 Published online on: 12 December 2018
Article
SOCS4 expressed by recombinant HSV protects against cytokine storm in a mouse model
Shuqi Ren, Xiaoqing Chen, Rongquan Huang, Grace Guoying Zhou, Zhuqing Yuan
Pages: 1509-1520 Published online on: 18 December 2018
Article
A 6‑gene risk score system constructed for predicting the clinical prognosis of pancreatic adenocarcinoma patients
Yan Liu, Dongyan Zhu, Hongjian Xing, Yi Hou, Yan Sun
Pages: 1521-1530 Published online on: 22 January 2019
Article
CTHRC1 overexpression promotes cervical carcinoma progression by activating the Wnt/PCP signaling pathway
Mei Zheng, Qin Zhou, Xingguang Liu, Chengze Wang, Gangli Liu
Pages: 1531-1538 Published online on: 10 January 2019
Article
Peroxiredoxin2 downregulation enhances hepatocellular carcinoma proliferation and migration, and is associated with unfavorable prognosis in patients
Bing Bai, Yanyan Lin, Jinjing Hu, Haiping Wang, Lu Li, Sheng Zhao, Jinduo Zhang, Wenbo Meng, Ping Yue, Zhongtian Bai, Xun Li
Pages: 1539-1548 Published online on: 22 January 2019
Article
miRNA-223 is an anticancer gene in human non-small cell lung cancer through the PI3K/AKT pathway by targeting EGFR
Hui-Ping Ma, Wei-Xiang Kong, Xiu-Ying Li, Wei Li, Yan Zhang, Yan Wu
Pages: 1549-1559 Published online on: 24 January 2019
Article
Pilot investigation of the mutation profile of PIK3CA/PTEN genes (PI3K pathway) in grade 3 endometrial cancer
Francesca Malentacchi, Irene Turrini, Flavia Sorbi, Elisabetta Projetto, Francesca Castiglione, Massimiliano Fambrini, Felice Petraglia, Serena Pillozzi, Ivo Noci
Pages: 1560-1574 Published online on: 18 December 2018
Article
miR‑107‑5p promotes tumor proliferation and invasion by targeting estrogen receptor‑α in endometrial carcinoma
Wei Bao, Yan Zhang, Shuangdi Li, Qiong Fan, Meiting Qiu, Yanan Wang, Yanli Li, Xiaoning Ji, Ye Yang, Zhenyu Sang, Wei Xu, Yongbin Yang, Sufang Wu, Yaping Zhu
Pages: 1575-1585 Published online on: 18 December 2018
Article
Identification of prognostic biomarkers for patients with hepatocellular carcinoma after hepatectomy
Xiangkun Wang, Xiwen Liao, Chengkun Yang, Ketuan Huang, Tingdong Yu, Long Yu, Chuangye Han, Guangzhi Zhu, Xianmin Zeng, Zhengqian Liu, Xin Zhou, Wei Qin, Hao Su, Xinping Ye, Tao Peng
Pages: 1586-1602 Published online on: 03 January 2019
Article
ERp29 counteracts the suppression of malignancy mediated by endoplasmic reticulum stress and promotes the metastasis of colorectal cancer
Lili Guo, Lili Ma, Chao Liu, Yan Lei, Na Tang, Yingxin Huang, Guan Huang, Dazhou Li, Qi Wang, Guanglong Liu, Minshan Tang, Zhiliang Jing, Yongjian Deng
Pages: 1603-1615 Published online on: 19 December 2018
Article
Imatinib‑induced apoptosis of gastric cancer cells is mediated by endoplasmic reticulum stress
Jung Lim Kim, Dae‑Hee Lee, Soyeon Jeong, Bo Ram Kim, Yoo Jin Na, Seong Hye Park, Min Jee Jo, Yoon A. Jeong, Sang Cheul Oh
Pages: 1616-1626 Published online on: 19 December 2018
Article
MicroRNA‑21 regulates the biological behavior of esophageal squamous cell carcinoma by targeting RASA1
Xiaohua Chen, Sina Cai, Baoxia Li, Xiaona Zhang, Wenhui Li, Henglun Liang, Xiaolong Cao, Liping Wang, Ziqing Wu
Pages: 1627-1637 Published online on: 19 December 2018
Article
miR‑498 inhibits the growth and metastasis of liver cancer by targeting ZEB2
Xu Zhang, Xueying Xu, Guohong Ge, Xueyan Zang, Meng Shao, Shengqiang Zou, Yu Zhang, Zheying Mao, Jiayin Zhang, Fei Mao, Hui Qian, Wenrong Xu
Pages: 1638-1648 Published online on: 21 December 2018
Article
SHCBP1 is a novel target and exhibits tumor‑promoting effects in gastric cancer
Ya‑Dong Dong, Yan‑Li Yuan, Hai‑Bo Yu, Guang‑Jin Tian, De‑Yu Li
Pages: 1649-1657 Published online on: 21 December 2018
Article
Electrochemotherapy of radioresistant head and neck squamous cell carcinoma cells and tumor xenografts
Martina Niksic Zakelj, Ajda Prevc, Simona Kranjc, Maja Cemazar, Vesna Todorovic, Monika Savarin, Janez Scancar, Tina Kosjek, Blaz Groselj, Primoz Strojan, Gregor Sersa
Pages: 1658-1668 Published online on: 09 January 2019
Article
MicroRNA‑3653 inhibits the growth and metastasis of hepatocellular carcinoma by inhibiting ITGB1
Lijuan Zhang, Tao Zhang, Zerun Deng, Lihua Sun
Pages: 1669-1677 Published online on: 16 January 2019
Article
The PI3K/AKT signaling pathway regulates ABCG2 expression and confers resistance to chemotherapy in human multiple myeloma
Lei Wang, Na Lin, Yan Li
Pages: 1678-1690 Published online on: 11 January 2019
Article
Downregulation of PRMT1, a histone arginine methyltransferase, by sodium propionate induces cell apoptosis in colon cancer
Tae Young Ryu, Kwangkho Kim, Mi-Young Son, Jeong-Ki Min, Janghwan Kim, Tae-Su Han, Dae-Soo Kim, Hyun-Soo Cho
Pages: 1691-1699 Published online on: 18 December 2018
Article
Gambogenic acid inhibits the proliferation of small‑cell lung cancer cells by arresting the cell cycle and inducing apoptosis
Tingting Huang, Hongming Zhang, Xiyong Wang, Lu Xu, Jinfang Jia, Xiaoli Zhu
Pages: 1700-1706 Published online on: 21 December 2018
Article
miR‑29a ameliorates ischemic injury of astrocytes in vitro by targeting the water channel protein aquaporin 4
Yueying Zheng, Caifei Pan, Manli Chen, Aijie Pei, Liwei Xie, Shengmei Zhu
Pages: 1707-1717 Published online on: 09 January 2019
Article
miR663a‑TTC22V1 axis inhibits colon cancer metastasis
Wei Tian, Yantao Du, Yuwan Ma, Baozhen Zhang, Liankun Gu, Jing Zhou, Dajun Deng
Pages: 1718-1728 Published online on: 16 January 2019
Article
Integrating modern approaches to pathogenetic concepts of malignant transformation of endometriosis
Hiroshi Kobayashi, Yuki Yamada, Naoki Kawahara, Kenji Ogawa, Chiharu Yoshimoto
Pages: 1729-1738 Published online on: 21 December 2018
Article
Upregulation of USP11 promotes epithelial‑to‑mesenchymal transition by deubiquitinating Snail in ovarian cancer
Weiwei Wang, Jing Wang, Hua Yan, Kai Zhang, Yang Liu
Pages: 1739-1748 Published online on: 12 December 2018
Article
Wnt7a predicts poor prognosis, and contributes to growth and metastasis in tongue squamous cell carcinoma
Bo Jia, Xiaoling Qiu, Hongxing Chu, Xiang Sun, Shuaimei Xu, Xinyuan Zhao, Jianjiang Zhao
Pages: 1749-1758 Published online on: 22 January 2019
Article
The HIF‑1α/miR‑224‑3p/ATG5 axis affects cell mobility and chemosensitivity by regulating hypoxia‑induced protective autophagy in glioblastoma and astrocytoma
Sihua Huang, Peng Qi, Ting Zhang, Fengtao Li, Xijing He
Pages: 1759-1768 Published online on: 13 December 2018
Article
Distinctive clinicopathological features and disease‑specific survival of adenoid cystic carcinoma and adenoid basal carcinoma in the lower female genital tract
Deyin Xing, Jiayun Lu
Pages: 1769-1778 Published online on: 12 December 2018
Article
Gallic acid has anticancer activity and enhances the anticancer effects of cisplatin in non‑small cell lung cancer A549 cells via the JAK/STAT3 signaling pathway
Tingxiu Zhang, Lijie Ma, Pengfei Wu, Wei Li, Ting Li, Rui Gu, Xiaoping Dan, Zhiwei Li, Xianming Fan, Zhenliang Xiao
Pages: 1779-1788 Published online on: 22 January 2019
Article
Downregulated Krüppel‑like factor 4 expression is associated with the aggressiveness of prostate cancer
Neng Zhang, Peng Su, Xiaoguang Li, Jianming Xi, Xu Li, Luo Xu
Pages: 1789-1796 Published online on: 22 January 2019
Article
lncRNA CASC2/miR‑18a‑5p axis regulates the malignant potential of nasopharyngeal carcinoma by targeting RBBP8
Wen‑Jie Miao, Dong‑Jie Yuan, Guo‑Zheng Zhang, Qi Liu, Hui‑Min Ma, Qian‑Qian Jin
Pages: 1797-1806 Published online on: 19 December 2018
Article
Cytoplasmic M‑CSF facilitates apoptosis resistance by inhibiting the HIF‑1α/BNIP3/Bax signalling pathway in MCF‑7 cells
Mengxia Zhang, Qi Liu, Lijun Li, Jing Ning, Jian Tu, Xiaoyong Lei, Zhongcheng Mo, Shengsong Tang
Pages: 1807-1816 Published online on: 21 December 2018
Article
Effect of NELL1 on lung cancer stem‑like cell differentiation
Yuanfen Zhai, Rongbin Wei, Shuang Sha, Chengzhao Lin, Heyong Wang, Xinquan Jiang, Gentao Liu
Pages: 1817-1826 Published online on: 03 January 2019
Article
PTEN downregulates WD repeat‑containing protein 66 in salivary adenoid cystic carcinoma
Yu Cao, Han Liu, Shi‑Lin Xia, Xi Zhang, Han Bai, Qian Yang, Jiang Li, Liwei Gao, Feng Jin, Min‑Jie Wei, Shi‑Long Lu, Jing Xiao
Pages: 1827-1836 Published online on: 13 December 2018
Article
Kenalog modified by ionizing radiation induces intrinsic apoptosis mediated by elevated levels of reactive oxygen species in melanoma cancer
Remigius Ambrose Kawala, Fatuma Jumapili Ramadhani, Hyo Jin Choi, Eun‑Hee Lee, Chul‑Hong Park, Byung Yeoup Chung, Hyoung‑Woo Bai
Pages: 1837-1850 Published online on: 19 December 2018
Article
Biological characterisation and application of human MTH1 and monoclonal antibody preparation
Chuyuan Chen, Xiaoping Li, Mengyue Gu, Rongrong Di, Nannan Kang, Lei Wang, Yisheng Lai, Yu Liu, Xuemei Ji
Pages: 1851-1862 Published online on: 19 December 2018
Article
Intravesical treatment of chemotherapeutic agents sensitizes bacillus Calmette‑Guerin by the modulation of the tumor immune environment
Shunta Hori, Makito Miyake, Yoshihiro Tatsumi, Yosuke Morizawa, Yasushi Nakai, Sayuri Onishi, Kenta Onishi, Kota Iida, Daisuke Gotoh, Yoshitaka Itami, Nobumichi Tanaka, Kiyohide Fujimoto
Pages: 1863-1874 Published online on: 10 January 2019
Article
XPC inhibition rescues cisplatin resistance via the Akt/mTOR signaling pathway in A549/DDP lung adenocarcinoma cells
Xue Teng, Xiao‑Fan Fan, Qi Li, Shuang Liu, Dong‑Yuan Wu, Shu‑Ya Wang, Yuanqi Shi, Mei Dong
Pages: 1875-1882 Published online on: 09 January 2019
Article
Momelotinib sensitizes glioblastoma cells to temozolomide by enhancement of autophagy via JAK2/STAT3 inhibition
Tie Liu, Anqi Li, Yulun Xu, Yu Xin
Pages: 1883-1892 Published online on: 16 January 2019
Article
Expression profiles and potential functions of circular RNAs in extracellular vesicles isolated from radioresistant glioma cells
Mengjie Zhao, Jinjin Xu, Shanliang Zhong, Yuchi Liu, Hong Xiao, Liangyuan Geng, Hongyi Liu
Pages: 1893-1900 Published online on: 18 January 2019
Article
Downregulation of BAG‑1 in T47D cells promotes resistance to tamoxifen via activation of the PI3K/Akt/mTOR signaling pathway
Su Lu, Yiyi Du, Fang Cui, Xinyi Feng, Yuanyuan Ma, Hong Liu
Pages: 1901-1910 Published online on: 22 January 2019
Article
CX3CL1 promotes lung cancer cell migration and invasion via the Src/focal adhesion kinase signaling pathway
Wangmi Liu, Yun Liang, Qian Chan, Libo Jiang, Jian Dong
Pages: 1911-1917 Published online on: 09 January 2019
Article
Interaction between C2ORF68 and HuR in human colorectal cancer
Zhaoxu Lv, Kunyan He, Lihong Shi, Kai Shi, Tingting Jiang, Yao Chen
Pages: 1918-1928 Published online on: 21 January 2019
Article
Identification and validation of alternative splicing isoforms as novel biomarker candidates in hepatocellular carcinoma
Peng Wu, Donghu Zhou, Yuqian Wang, Weiran Lin, Aihua Sun, Handong Wei, Yi Fang, Xianling Cong, Ying Jiang
Pages: 1929-1937 Published online on: 21 December 2018
Article
MicroRNA‑486‑5p functions as a tumor suppressor of proliferation and cancer stem‑like cell properties by targeting Sirt1 in liver cancer
Xinlong Yan, Xinhui Liu, Zhaohai Wang, Qian Cheng, Guanghong Ji, Hui Yang, Lingfei Wan, Chen Ge, Quan Zeng, Hua Huang, Jiafei Xi, Lijuan He, Xue Nan, Wen Yue, Xuetao Pei
Pages: 1938-1948 Published online on: 13 December 2018
Article
PEA‑15 contributes to the clinicopathology and AKT‑regulated cisplatin resistance in gastric cancer
Xian Jiang, Changlu Zhang, Weidong Li, Dalei Jiang, Zheng Wei, Mei Lv, Xiangjun Xie, Xueying Sun
Pages: 1949-1959 Published online on: 18 December 2018
Article
Radiosensitization of esophageal carcinoma cells by knockdown of HMGB1 expression
Xueyuan Zhang, Xingxiao Yang, Shuchai Zhu, Qiaofang Li, Naiyi Zou
Pages: 1960-1970 Published online on: 10 December 2018
Article
Inhibition of PIKfyve using YM201636 suppresses the growth of liver cancer via the induction of autophagy
Jiu‑Zhou Hou, Zhuo‑Qing Xi, Jie Niu, Wei Li, Xiao Wang, Chao Liang, Hua Sun, Dong Fang, Song‑Qiang Xie
Pages: 1971-1979 Published online on: 12 December 2018
Article
The role of ZBTB38 in promoting migration and invasive growth of bladder cancer cells
Jingchen Jing, Jie Liu, Yaochun Wang, Miao Zhang, Lu Yang, Feiyu Shi, Peijun Liu, Junjun She
Pages: 1980-1990 Published online on: 18 December 2018
Article
Combined inhibition of sonic Hedgehog signaling and histone deacetylase is an effective treatment for liver cancer
Jingmin Li, Heng Cai, Hongxing Li, Yanguo Liu, Yirong Wang, Yan Shi, Yan Sun, Haoran Song, Dong Wang
Pages: 1991-1997 Published online on: 23 January 2019
Article
Stanniocalcin‑1 promotes cell proliferation, chemoresistance and metastasis in hypoxic gastric cancer cells via Bcl‑2
Yan Wang, Zihao Qi, Menglong Zhou, Wang Yang, Ran Hu, Guichao Li, Xuejun Ma, Zhen Zhang
Pages: 1998-2008 Published online on: 23 January 2019
Article
17β‑hydroxysteroid dehydrogenase 4 induces liver cancer proliferation‑associated genes via STAT3 activation
Xin Lu, Lingyu Kong, Xi Wang, Weiran Liu, Panpan Ma, Lingling Jiang
Pages: 2009-2019 Published online on: 23 January 2019
Article
Shikonin induces an anti‑tumor effect on murine mammary cancer via p38‑dependent apoptosis
Jiuxiang Xu, Keiichi Koizumi, Mengxin Liu, Yusuke Mizuno, Mikiko Suzaki, Hirofumi Iitsuka, Akiko Inujima, Makoto Fujimoto, Naotoshi Shibahara, Yutaka Shimada
Pages: 2020-2026 Published online on: 11 January 2019
Article
Disruption of MAPK1 expression in the ERK signalling pathway and the RUNX1‑RUNX1T1 fusion gene attenuate the differentiation and proliferation and induces the growth arrest in t(8;21) leukaemia cells
Salem Ali Al‑Salem Bashanfer, Mohamed Saleem, Olaf Heidenreich, Emmanuel Jairaj Moses, Narazah Mohd Yusoff
Pages: 2027-2040 Published online on: 12 December 2018
Article
Early decrease in serum amphiregulin or vascular endothelial growth factor levels predicts sorafenib efficacy in hepatocellular carcinoma
Corinne Godin, Sandra Bodeau, Zuzana Saidak, Christophe Louandre, Catherine François, Jean‑Claude Barbare, Romain Coriat, Antoine Galmiche, Chloé Sauzay
Pages: 2041-2050 Published online on: 10 December 2018
Article
Introduction of exogenous wild‑type p53 mediates the regulation of oncoprotein 18/stathmin signaling via nuclear factor‑κB in non‑small cell lung cancer NCI‑H1299 cells
Sangyan Chen, Yan Zhao, Fang Shen, Dan Long, Ting Yu, Xuechi Lin
Pages: 2051-2059 Published online on: 10 January 2019
Article
Anticancer effects of methotrexate in combination with α‑tocopherol and α‑tocopherol succinate on triple‑negative breast cancer
Chyou‑Wei Wei, Yung‑Luen Yu, Yu‑Hsun Chen, Yu‑Ting Hung, Giou‑Teng Yiang
Pages: 2060-2066 Published online on: 09 January 2019
Correction
[Corrigendum] High expression of RELM-α correlates with poor prognosis and promotes angiogenesis in gastric cancer
Ping Chen, Deshou Zhao, Weiyi Wang, Yongping Zhang, Yaozong Yuan, Lifu Wang, Yunlin Wu
Pages: 2067-2067 Published online on: 17 December 2018
Correction
