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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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March-2019 Volume 41 Issue 3

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

Predicting resistance to endocrine therapy in breast cancer: It's time for epigenetic biomarkers (Review)

Mário Fontes‑Sousa, Maria Amorim, Sofia Salta, Susana Palma De Sousa, Rui Henrique, Carmen Jerónimo
Pages: 1431-1438
Published online on: 11 January 2019

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Review

MicroRNAs and the PTEN/PI3K/Akt pathway in gastric cancer (Review)

Mingli Hu, Shixuan Zhu, Shengwei Xiong, Xingxing Xue, Xiaodong Zhou
Pages: 1439-1454
Published online on: 10 January 2019

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Review

Ubiquitination‑deubiquitination in the Hippo signaling pathway (Review)

Yanting Liu, Jun Deng
Pages: 1455-1475
Published online on: 08 January 2019

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Article Open Access

Chitosan-coated liposomes loaded with butyric acid demonstrate anticancer and anti-inflammatory activity in human hepatoma HepG2 cells

Vincenzo Quagliariello, Mario Masarone, Emilia Armenia, Aldo Giudice, Manlio Barbarisi, Michele Caraglia, Alfonso Barbarisi, Marcello Persico
Pages: 1476-1486
Published online on: 13 December 2018

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Article Open Access

Bromodomain‑containing protein 7 sensitizes breast cancer cells to paclitaxel by activating Bcl2‑antagonist/killer protein

Jinqi Ma, Weihong Niu, Xinye Wang, Yao Zhou, Heran Wang, Fengxia Liu, Yukun Liu, Jie Guo, Wei Xiong, Zhaoyang Zeng, Songqing Fan, Xiaoling Li, Xinmin Nie, Guiyuan Li, Rong Gui, Yanwei Luo, Ming Zhou
Pages: 1487-1496
Published online on: 21 December 2018

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Article Open Access

MicroRNA‑200a suppresses migration and invasion and enhances the radiosensitivity of NSCLC cells by inhibiting the HGF/c‑Met signaling pathway

Menghua Du, Jin Wang, Huan Chen, Shouli Wang, Liesong Chen, Yichang Xu, Fengtao Su, Xueguan Lu
Pages: 1497-1508
Published online on: 12 December 2018

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Article Open Access

SOCS4 expressed by recombinant HSV protects against cytokine storm in a mouse model

Shuqi Ren, Xiaoqing Chen, Rongquan Huang, Grace Guoying Zhou, Zhuqing Yuan
Pages: 1509-1520
Published online on: 18 December 2018

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Article Open Access

A 6‑gene risk score system constructed for predicting the clinical prognosis of pancreatic adenocarcinoma patients

Yan Liu, Dongyan Zhu, Hongjian Xing, Yi Hou, Yan Sun
Pages: 1521-1530
Published online on: 22 January 2019

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Article Open Access

CTHRC1 overexpression promotes cervical carcinoma progression by activating the Wnt/PCP signaling pathway

Mei Zheng, Qin Zhou, Xingguang Liu, Chengze Wang, Gangli Liu
Pages: 1531-1538
Published online on: 10 January 2019

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Article Open Access

Peroxiredoxin2 downregulation enhances hepatocellular carcinoma proliferation and migration, and is associated with unfavorable prognosis in patients

Bing Bai, Yanyan Lin, Jinjing Hu, Haiping Wang, Lu Li, Sheng Zhao, Jinduo Zhang, Wenbo Meng, Ping Yue, Zhongtian Bai, Xun  Li
Pages: 1539-1548
Published online on: 22 January 2019

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Article Open Access

miRNA-223 is an anticancer gene in human non-small cell lung cancer through the PI3K/AKT pathway by targeting EGFR

Hui-Ping Ma, Wei-Xiang Kong, Xiu-Ying Li, Wei Li, Yan Zhang, Yan Wu
Pages: 1549-1559
Published online on: 24 January 2019

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Article Open Access

Pilot investigation of the mutation profile of PIK3CA/PTEN genes (PI3K pathway) in grade 3 endometrial cancer

Francesca Malentacchi, Irene Turrini, Flavia Sorbi, Elisabetta Projetto, Francesca Castiglione, Massimiliano Fambrini, Felice Petraglia, Serena Pillozzi, Ivo Noci
Pages: 1560-1574
Published online on: 18 December 2018

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Article Open Access

miR‑107‑5p promotes tumor proliferation and invasion by targeting estrogen receptor‑α in endometrial carcinoma

Wei Bao, Yan Zhang, Shuangdi Li, Qiong Fan, Meiting Qiu, Yanan Wang, Yanli Li, Xiaoning Ji, Ye Yang, Zhenyu Sang, Wei Xu, Yongbin Yang, Sufang Wu, Yaping Zhu
Pages: 1575-1585
Published online on: 18 December 2018

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Article Open Access

Identification of prognostic biomarkers for patients with hepatocellular carcinoma after hepatectomy

Xiangkun Wang, Xiwen Liao, Chengkun Yang, Ketuan Huang, Tingdong Yu, Long Yu, Chuangye Han, Guangzhi Zhu, Xianmin Zeng, Zhengqian Liu, Xin Zhou, Wei Qin, Hao Su, Xinping Ye, Tao Peng
Pages: 1586-1602
Published online on: 03 January 2019

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Article Open Access

ERp29 counteracts the suppression of malignancy mediated by endoplasmic reticulum stress and promotes the metastasis of colorectal cancer

Lili Guo, Lili Ma, Chao Liu, Yan Lei, Na Tang, Yingxin Huang, Guan Huang, Dazhou Li, Qi Wang, Guanglong Liu, Minshan Tang, Zhiliang Jing, Yongjian Deng
Pages: 1603-1615
Published online on: 19 December 2018

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Article Open Access

Imatinib‑induced apoptosis of gastric cancer cells is mediated by endoplasmic reticulum stress

Jung Lim Kim, Dae‑Hee Lee, Soyeon Jeong, Bo Ram Kim, Yoo Jin Na, Seong Hye Park, Min Jee Jo, Yoon A. Jeong, Sang Cheul Oh
Pages: 1616-1626
Published online on: 19 December 2018

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Article Open Access

MicroRNA‑21 regulates the biological behavior of esophageal squamous cell carcinoma by targeting RASA1

Xiaohua Chen, Sina Cai, Baoxia Li, Xiaona Zhang, Wenhui Li, Henglun Liang, Xiaolong Cao, Liping Wang, Ziqing Wu
Pages: 1627-1637
Published online on: 19 December 2018

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Article Open Access

miR‑498 inhibits the growth and metastasis of liver cancer by targeting ZEB2

Xu Zhang, Xueying Xu, Guohong Ge, Xueyan Zang, Meng Shao, Shengqiang Zou, Yu Zhang, Zheying Mao, Jiayin Zhang, Fei Mao, Hui Qian, Wenrong Xu
Pages: 1638-1648
Published online on: 21 December 2018

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Article Open Access

SHCBP1 is a novel target and exhibits tumor‑promoting effects in gastric cancer

Ya‑Dong Dong, Yan‑Li Yuan, Hai‑Bo Yu, Guang‑Jin Tian, De‑Yu Li
Pages: 1649-1657
Published online on: 21 December 2018

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Article Open Access

Electrochemotherapy of radioresistant head and neck squamous cell carcinoma cells and tumor xenografts

Martina Niksic Zakelj, Ajda Prevc, Simona Kranjc, Maja Cemazar, Vesna Todorovic, Monika Savarin, Janez Scancar, Tina Kosjek, Blaz Groselj, Primoz Strojan, Gregor Sersa
Pages: 1658-1668
Published online on: 09 January 2019

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Article Open Access

MicroRNA‑3653 inhibits the growth and metastasis of hepatocellular carcinoma by inhibiting ITGB1

Lijuan Zhang, Tao Zhang, Zerun Deng, Lihua Sun
Pages: 1669-1677
Published online on: 16 January 2019

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Article Open Access

The PI3K/AKT signaling pathway regulates ABCG2 expression and confers resistance to chemotherapy in human multiple myeloma

Lei Wang, Na Lin, Yan Li
Pages: 1678-1690
Published online on: 11 January 2019

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Article Open Access

Downregulation of PRMT1, a histone arginine methyltransferase, by sodium propionate induces cell apoptosis in colon cancer

Tae Young Ryu, Kwangkho Kim, Mi-Young Son, Jeong-Ki Min, Janghwan Kim, Tae-Su Han, Dae-Soo Kim, Hyun-Soo Cho
Pages: 1691-1699
Published online on: 18 December 2018

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Article Open Access

Gambogenic acid inhibits the proliferation of small‑cell lung cancer cells by arresting the cell cycle and inducing apoptosis

Tingting Huang, Hongming Zhang, Xiyong Wang, Lu Xu, Jinfang Jia, Xiaoli Zhu
Pages: 1700-1706
Published online on: 21 December 2018

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Article Open Access

miR‑29a ameliorates ischemic injury of astrocytes in vitro by targeting the water channel protein aquaporin 4

Yueying Zheng, Caifei Pan, Manli Chen, Aijie Pei, Liwei Xie, Shengmei Zhu
Pages: 1707-1717
Published online on: 09 January 2019

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Article Open Access

miR663a‑TTC22V1 axis inhibits colon cancer metastasis

Wei Tian, Yantao Du, Yuwan Ma, Baozhen Zhang, Liankun Gu, Jing Zhou, Dajun Deng
Pages: 1718-1728
Published online on: 16 January 2019

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Article

Integrating modern approaches to pathogenetic concepts of malignant transformation of endometriosis

Hiroshi Kobayashi, Yuki Yamada, Naoki Kawahara, Kenji Ogawa, Chiharu Yoshimoto
Pages: 1729-1738
Published online on: 21 December 2018

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Article

Upregulation of USP11 promotes epithelial‑to‑mesenchymal transition by deubiquitinating Snail in ovarian cancer

Weiwei Wang, Jing Wang, Hua Yan, Kai Zhang, Yang Liu
Pages: 1739-1748
Published online on: 12 December 2018

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Article

Wnt7a predicts poor prognosis, and contributes to growth and metastasis in tongue squamous cell carcinoma

Bo Jia, Xiaoling Qiu, Hongxing Chu, Xiang Sun, Shuaimei Xu, Xinyuan Zhao, Jianjiang Zhao
Pages: 1749-1758
Published online on: 22 January 2019

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Article

The HIF‑1α/miR‑224‑3p/ATG5 axis affects cell mobility and chemosensitivity by regulating hypoxia‑induced protective autophagy in glioblastoma and astrocytoma

Sihua Huang, Peng Qi, Ting Zhang, Fengtao Li, Xijing He
Pages: 1759-1768
Published online on: 13 December 2018

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Article

Distinctive clinicopathological features and disease‑specific survival of adenoid cystic carcinoma and adenoid basal carcinoma in the lower female genital tract

Deyin Xing, Jiayun Lu
Pages: 1769-1778
Published online on: 12 December 2018

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Article

Gallic acid has anticancer activity and enhances the anticancer effects of cisplatin in non‑small cell lung cancer A549 cells via the JAK/STAT3 signaling pathway

Tingxiu Zhang, Lijie Ma, Pengfei Wu, Wei Li, Ting Li, Rui Gu, Xiaoping Dan, Zhiwei Li, Xianming Fan, Zhenliang Xiao
Pages: 1779-1788
Published online on: 22 January 2019

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Article

Downregulated Krüppel‑like factor 4 expression is associated with the aggressiveness of prostate cancer

Neng Zhang, Peng Su, Xiaoguang Li, Jianming Xi, Xu Li, Luo Xu
Pages: 1789-1796
Published online on: 22 January 2019

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Article

lncRNA CASC2/miR‑18a‑5p axis regulates the malignant potential of nasopharyngeal carcinoma by targeting RBBP8

Wen‑Jie Miao, Dong‑Jie Yuan, Guo‑Zheng Zhang, Qi Liu, Hui‑Min Ma, Qian‑Qian Jin
Pages: 1797-1806
Published online on: 19 December 2018

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Article

Cytoplasmic M‑CSF facilitates apoptosis resistance by inhibiting the HIF‑1α/BNIP3/Bax signalling pathway in MCF‑7 cells

Mengxia Zhang, Qi Liu, Lijun Li, Jing Ning, Jian Tu, Xiaoyong Lei, Zhongcheng Mo, Shengsong Tang
Pages: 1807-1816
Published online on: 21 December 2018

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Article

Effect of NELL1 on lung cancer stem‑like cell differentiation

Yuanfen Zhai, Rongbin Wei, Shuang Sha, Chengzhao  Lin, Heyong Wang, Xinquan Jiang, Gentao Liu
Pages: 1817-1826
Published online on: 03 January 2019

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Article

PTEN downregulates WD repeat‑containing protein 66 in salivary adenoid cystic carcinoma

Yu Cao, Han Liu, Shi‑Lin Xia, Xi Zhang, Han Bai, Qian Yang, Jiang Li, Liwei Gao, Feng Jin, Min‑Jie Wei, Shi‑Long Lu, Jing Xiao
Pages: 1827-1836
Published online on: 13 December 2018

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Article

Kenalog modified by ionizing radiation induces intrinsic apoptosis mediated by elevated levels of reactive oxygen species in melanoma cancer

Remigius Ambrose Kawala, Fatuma Jumapili Ramadhani, Hyo Jin Choi, Eun‑Hee Lee, Chul‑Hong Park, Byung Yeoup Chung, Hyoung‑Woo Bai
Pages: 1837-1850
Published online on: 19 December 2018

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Article

Biological characterisation and application of human MTH1 and monoclonal antibody preparation

Chuyuan Chen, Xiaoping Li, Mengyue Gu, Rongrong Di, Nannan Kang, Lei Wang, Yisheng Lai, Yu Liu, Xuemei Ji
Pages: 1851-1862
Published online on: 19 December 2018

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Article

Intravesical treatment of chemotherapeutic agents sensitizes bacillus Calmette‑Guerin by the modulation of the tumor immune environment

Shunta Hori, Makito Miyake, Yoshihiro Tatsumi, Yosuke Morizawa, Yasushi Nakai, Sayuri Onishi, Kenta Onishi, Kota Iida, Daisuke Gotoh, Yoshitaka Itami, Nobumichi Tanaka, Kiyohide Fujimoto
Pages: 1863-1874
Published online on: 10 January 2019

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Article

XPC inhibition rescues cisplatin resistance via the Akt/mTOR signaling pathway in A549/DDP lung adenocarcinoma cells

Xue Teng, Xiao‑Fan Fan, Qi Li, Shuang Liu, Dong‑Yuan Wu, Shu‑Ya Wang, Yuanqi Shi, Mei Dong
Pages: 1875-1882
Published online on: 09 January 2019

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Article

Momelotinib sensitizes glioblastoma cells to temozolomide by enhancement of autophagy via JAK2/STAT3 inhibition

Tie Liu, Anqi Li, Yulun Xu, Yu Xin
Pages: 1883-1892
Published online on: 16 January 2019

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Article

Expression profiles and potential functions of circular RNAs in extracellular vesicles isolated from radioresistant glioma cells

Mengjie Zhao, Jinjin Xu, Shanliang Zhong, Yuchi Liu, Hong Xiao, Liangyuan Geng, Hongyi Liu
Pages: 1893-1900
Published online on: 18 January 2019

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Article

Downregulation of BAG‑1 in T47D cells promotes resistance to tamoxifen via activation of the PI3K/Akt/mTOR signaling pathway

Su Lu, Yiyi Du, Fang Cui, Xinyi Feng, Yuanyuan Ma, Hong Liu
Pages: 1901-1910
Published online on: 22 January 2019

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Article

CX3CL1 promotes lung cancer cell migration and invasion via the Src/focal adhesion kinase signaling pathway

Wangmi Liu, Yun Liang, Qian Chan, Libo Jiang, Jian Dong
Pages: 1911-1917
Published online on: 09 January 2019

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Article

Interaction between C2ORF68 and HuR in human colorectal cancer

Zhaoxu Lv, Kunyan He, Lihong Shi, Kai Shi, Tingting Jiang, Yao Chen
Pages: 1918-1928
Published online on: 21 January 2019

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Article

Identification and validation of alternative splicing isoforms as novel biomarker candidates in hepatocellular carcinoma

Peng Wu, Donghu Zhou, Yuqian Wang, Weiran Lin, Aihua Sun, Handong Wei, Yi Fang, Xianling Cong, Ying Jiang
Pages: 1929-1937
Published online on: 21 December 2018

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Article

MicroRNA‑486‑5p functions as a tumor suppressor of proliferation and cancer stem‑like cell properties by targeting Sirt1 in liver cancer

Xinlong Yan, Xinhui Liu, Zhaohai Wang, Qian Cheng, Guanghong Ji, Hui Yang, Lingfei Wan, Chen Ge, Quan Zeng, Hua Huang, Jiafei Xi, Lijuan He, Xue Nan, Wen Yue, Xuetao Pei
Pages: 1938-1948
Published online on: 13 December 2018

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Article

PEA‑15 contributes to the clinicopathology and AKT‑regulated cisplatin resistance in gastric cancer

Xian Jiang, Changlu Zhang, Weidong Li, Dalei Jiang, Zheng Wei, Mei Lv, Xiangjun Xie, Xueying Sun
Pages: 1949-1959
Published online on: 18 December 2018

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Article

Radiosensitization of esophageal carcinoma cells by knockdown of HMGB1 expression

Xueyuan Zhang, Xingxiao Yang, Shuchai Zhu, Qiaofang Li, Naiyi Zou
Pages: 1960-1970
Published online on: 10 December 2018

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Article

Inhibition of PIKfyve using YM201636 suppresses the growth of liver cancer via the induction of autophagy

Jiu‑Zhou Hou, Zhuo‑Qing Xi, Jie Niu, Wei Li, Xiao Wang, Chao Liang, Hua Sun, Dong Fang, Song‑Qiang Xie
Pages: 1971-1979
Published online on: 12 December 2018

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Article

The role of ZBTB38 in promoting migration and invasive growth of bladder cancer cells

Jingchen Jing, Jie Liu, Yaochun Wang, Miao Zhang, Lu Yang, Feiyu Shi, Peijun Liu, Junjun She
Pages: 1980-1990
Published online on: 18 December 2018

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Article

Combined inhibition of sonic Hedgehog signaling and histone deacetylase is an effective treatment for liver cancer

Jingmin Li, Heng Cai, Hongxing Li, Yanguo Liu, Yirong Wang, Yan Shi, Yan Sun, Haoran Song, Dong Wang
Pages: 1991-1997
Published online on: 23 January 2019

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Article

Stanniocalcin‑1 promotes cell proliferation, chemoresistance and metastasis in hypoxic gastric cancer cells via Bcl‑2

Yan Wang, Zihao Qi, Menglong Zhou, Wang Yang, Ran Hu, Guichao Li, Xuejun Ma, Zhen Zhang
Pages: 1998-2008
Published online on: 23 January 2019

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Article

17β‑hydroxysteroid dehydrogenase 4 induces liver cancer proliferation‑associated genes via STAT3 activation

Xin Lu, Lingyu Kong, Xi Wang, Weiran Liu, Panpan Ma, Lingling Jiang
Pages: 2009-2019
Published online on: 23 January 2019

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Article

Shikonin induces an anti‑tumor effect on murine mammary cancer via p38‑dependent apoptosis

Jiuxiang Xu, Keiichi Koizumi, Mengxin Liu, Yusuke Mizuno, Mikiko Suzaki, Hirofumi Iitsuka, Akiko Inujima, Makoto Fujimoto, Naotoshi Shibahara, Yutaka Shimada
Pages: 2020-2026
Published online on: 11 January 2019

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Article

Disruption of MAPK1 expression in the ERK signalling pathway and the RUNX1‑RUNX1T1 fusion gene attenuate the differentiation and proliferation and induces the growth arrest in t(8;21) leukaemia cells

Salem Ali Al‑Salem Bashanfer, Mohamed Saleem, Olaf Heidenreich, Emmanuel Jairaj Moses, Narazah Mohd Yusoff
Pages: 2027-2040
Published online on: 12 December 2018

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Article

Early decrease in serum amphiregulin or vascular endothelial growth factor levels predicts sorafenib efficacy in hepatocellular carcinoma

Corinne Godin, Sandra Bodeau, Zuzana Saidak, Christophe Louandre, Catherine François, Jean‑Claude Barbare, Romain Coriat, Antoine Galmiche, Chloé Sauzay
Pages: 2041-2050
Published online on: 10 December 2018

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Article

Introduction of exogenous wild‑type p53 mediates the regulation of oncoprotein 18/stathmin signaling via nuclear factor‑κB in non‑small cell lung cancer NCI‑H1299 cells

Sangyan Chen, Yan Zhao, Fang Shen, Dan Long, Ting Yu, Xuechi Lin
Pages: 2051-2059
Published online on: 10 January 2019

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Article

Anticancer effects of methotrexate in combination with α‑tocopherol and α‑tocopherol succinate on triple‑negative breast cancer

Chyou‑Wei Wei, Yung‑Luen Yu, Yu‑Hsun Chen, Yu‑Ting Hung, Giou‑Teng Yiang
Pages: 2060-2066
Published online on: 09 January 2019

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[Corrigendum] High expression of RELM-α correlates with poor prognosis and promotes angiogenesis in gastric cancer

Ping Chen, Deshou Zhao, Weiyi Wang, Yongping Zhang, Yaozong Yuan, Lifu Wang, Yunlin Wu
Pages: 2067-2067
Published online on: 17 December 2018

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[Corrigendum] Oncogenic function of Plac1 on the proliferation and metastasis in hepatocellular carcinoma cells

Yuan Wu, Xiaocong Lin, Xiaoqing Di, Yonghua Chen, Hanning Zhao, Xin Wang
Pages: 2068-2068
Published online on: 04 January 2019

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Journal Cover
March-2026 Volume 55 Issue 3

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Collaborative breakthroughs in precision diagnosis and treatment of nasopharyngeal cancer: Biomarker‑driven screening and endoscopic minimally invasive surgery reshape the new paradigm of early intervention (Review)

E Jin, Wang Lin, Xiandong Zeng
Article Number: 53
Published online on: 23 January 2026

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Key immune cells in the tumor immune microenvironment of colorectal cancer: Roles and research advances (Review)

Ming Qiu, Chongyuan Lan, Minglin Lin, Hui Ma
Article Number: 52
Published online on: 21 January 2026

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[Corrigendum] Icaritin acts synergistically with epirubicin to suppress bladder cancer growth through inhibition of autophagy

Xiu-Wu Pan, Lin Li, Yi Huang, Hai Huang, Dan-Feng Xu, Yi Gao, Lu Chen, Ji-Zhong Ren, Jian-Wei Cao, Yi Hong, Xin-Gang Cui
Article Number: 51
Published online on: 21 January 2026

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Epigenetic mechanisms and therapeutic advances in diffuse midline glioma (Review)

Wenbo Wu, Wenlin Chen, Wenbin Ma, Yu Wang
Article Number: 50
Published online on: 20 January 2026

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Recapitulating lung cancer metastasis in vitro: Advances in organoid models and challenges in clinical translation (Review)

Jian Jiang, Guomin Dong, Zhiyun Zhang, Xiaoyuan Lei, Fanshu Huang, Suoni Li, Jiequn Ma, Jie Bai, Qian Ge, Hui Wei, Zheng Zhao
Article Number: 49
Published online on: 20 January 2026

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GPR176 enhances the epithelial‑mesenchymal transition in gastric cancer cells by activating the PI3K/AKT/mTOR signaling pathway

Guangchuan Mu, Kaiyan Li, Chaozhen Hu, Jintao Cai, Huichao Ruan, Guanyu Zhu, Dang Liu
Article Number: 48
Published online on: 19 January 2026

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HMBOX1 inhibits hepatocellular carcinoma progression via PTPN1 mediated AKT1 phosphorylation

Chenning Zhang, Yu Jiang, Jiahui Liu, Wenyu Zhang, Jie Qi, Qing Wen, Hengli Zhao
Article Number: 47
Published online on: 19 January 2026

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[Retracted] Prognostic significance of miR‑218 in human hepatocellular carcinoma and its role in cell growth

Kangsheng Tu, Chao Li, Xin Zheng, Wei Yang, Yingmin Yao, Qingguang Liu
Article Number: 46
Published online on: 19 January 2026

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Review Open Access

Tumor microenvironment in bone sarcomas: Implications for immunotherapy and emerging therapeutic vulnerabilities (Review)

Wentao Li, Lijun Lv, Yibin Jin, Xin Yuan
Article Number: 45
Published online on: 16 January 2026

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Immunotherapy after EGFR‑TKI treatment in advanced non‑small cell lung cancer: Current status and future perspectives (Review)

Huiyuan Ma, Longhui Li, Conghan Jiao, Yanyan Cheng, Jiayu He, Chen Jiang, Qian Tong, Dan Yi, Ying Zhang
Article Number: 44
Published online on: 16 January 2026

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[Corrigendum] Triptolide inhibits JAK2/STAT3 signaling and induces lethal autophagy through ROS generation in cisplatin‑resistant SKOV3/DDP ovarian cancer cells

Yanying Zhong, Fuyin Le, Jiao Cheng, Chen Luo, Xiali Zhang, Xingwu Wu, Fang Xu, Qi Zuo, Buzhen Tan
Article Number: 43
Published online on: 13 January 2026

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Review Open Access

Role of tumor‑infiltrating lymphocytes and miR‑155 in breast cancer: Insights into carcinogenesis and their potential as prognostic biomarkers (Review)

Miriam Monteiro Alvares‑Vilela, Franciele Schlemmer, Sabrina Simplício de Araújo Romero Ferrari, Mary-Ann Elvina Xavier, Ricardo Titze‑de‑Almeida
Article Number: 42
Published online on: 14 January 2026

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Article Open Access

CDK1 depletion suppresses glioma malignancy through cell cycle pathway regulation: Mechanistic insights from functional and molecular profiling

Yu Wang, Huandi Zhou, Xuetao Han, Dongdong Zhang, Liubing Hou, Haonan Li, Tianyi Fan, Sijie Li, Xiaoying Xue
Article Number: 41
Published online on: 12 January 2026

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Retraction Open Access

[Retracted] Downregulated microRNA‑200a promotes EMT and tumor growth through the Wnt/β‑catenin pathway by targeting the E‑cadherin repressors ZEB1/ZEB2 in gastric adenocarcinoma

Ningning Cong, Ping Du, Anling Zhang, Fajuan Shen, Juan Su, Peiyu Pu, Tao Wang, Jie Zjang, Chunsheng Kang, Qingyu Zhang
Article Number: 40
Published online on: 12 January 2026

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Review Open Access

Advances in targeting KRAS mutations: A promising approach for the treatment of non‑small cell lung cancer (Review)

Upesh Sharma, Jincheng Song, Hemraj Kandu, Yue Zhu, Zhaoxia Dai
Article Number: 39
Published online on: 08 January 2026

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Correction Open Access

[Corrigendum] CXCR6 predicts poor prognosis in gastric cancer and promotes tumor metastasis through epithelial-mesenchymal transition

Jie-Jie Jin, Fa-Xiang Dai, Zi-Wen Long, Hong Cai, Xiao-Wen Liu, Ye Zhou, Qi Hong, Qiong-Zhu Dong, Ya-Nong Wang, Hua Huang
Article Number: 38
Published online on: 05 January 2026

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Journal Cover
April-2026 Volume 55 Issue 4

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

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