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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
August-2021 Volume 46 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article

TMEM100 negatively regulated by microRNA‑106b facilitates cellular apoptosis by suppressing survivin expression in NSCLC

Jun Ma, Tingting Yan, Yongrui Bai, Ming Ye, Chunhui Ma, Xiumei Ma, Lei Zhang
Article Number: 185
Published online on: 07 July 2021

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Review Open Access

Abnormal function of telomere protein TRF2 induces cell mutation and the effects of environmental tumor‑promoting factors (Review)

Zhengyi Wang, Xiaoying Wu
Article Number: 184
Published online on: 07 July 2021

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Article

EphA8 inhibits cell apoptosis via AKT signaling and is associated with poor prognosis in breast cancer

Gui-Hua Wang, Kan Ni, Changjiang Gu, Jianfei Huang, Jing Chen, Xu-Dong Wang, Qichao Ni
Article Number: 183
Published online on: 06 July 2021

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Review

Tumorigenic effect of TERT and its potential therapeutic target in NSCLC (Review)

Liu Yang, Na Li, Meng Wang, Yan-Hua Zhang, Lu-Da Yan, Wen Zhou, Zhi-Qiong Yu, Xiao-Chun Peng, Jun Cai
Article Number: 182
Published online on: 06 July 2021

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Article Open Access

lncRNA MALAT1/miR‑26a/26b/ST8SIA4 axis mediates cell invasion and migration in breast cancer cell lines

Nan Wang, Shengji Cao, Xiaoxi Wang, Lina Zhang, Hong Yuan, Xiaolu Ma
Article Number: 181
Published online on: 06 July 2021

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Article Open Access

RORβ suppresses the stemness of gastric cancer cells by downregulating the activity of the Wnt signaling pathway

Zhenzhen Wen, Ming Chen, Wenhao Guo, Ke Guo, Ping Du, Yanfei Fang, Min Gao, Qiang Wang
Article Number: 180
Published online on: 06 July 2021

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Retraction Open Access

[Retracted] MicroRNA‑154 functions as a tumor suppressor in osteosarcoma by targeting Wnt5a

Hui Zhou, Minglei Zhang, Hongping Yuan, Wei Zheng, Chunyan Meng, Dongxu Zhao
Article Number: 179
Published online on: 05 July 2021

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Retraction Open Access

[Retracted] Long non‑coding RNA MCM3AP‑AS1 drives ovarian cancer progression via the microRNA‑143‑3p/TAK1 axis

Jihong Wen, Shumei Han, Man Cui, Yanli Wang
Article Number: 178
Published online on: 01 July 2021

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Review

Value of methylation markers in colorectal cancer (Review)

Can Kong, Tao Fu
Article Number: 177
Published online on: 30 June 2021

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Article Open Access

TMEM229A suppresses non‑small cell lung cancer progression via inactivating the ERK pathway

Xilin Zhang, Ying He, Yan Jiang, Ying Bao, Qiuqiang Chen, Dong Xie, Huanming Yu, Xiang Wang
Article Number: 176
Published online on: 29 June 2021

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Correction Open Access

[Corrigendum] miR‑29a inhibits human retinoblastoma progression by targeting STAT3

Shu Liu, Xiaomeng Zhang, Chunmei Hu, Yingxue Wang, Chunling Xu
Article Number: 175
Published online on: 28 June 2021

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Retraction Open Access

[Retracted] Synthetic miR‑145 mimic inhibits multiple myeloma cell growth in vitro and in vivo

Qi Zhang, Weiqun Yan, Yang Bai, Hao Xu, Changhao Fu, Wenwen Zheng, Yingqiao Zhu, Jie Ma
Article Number: 174
Published online on: 28 June 2021

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Article Open Access

Anti‑HER3 monoclonal antibody exerts antitumor activity in a mouse model of colorectal adenocarcinoma

Teizo Asano, Tomokazu Ohishi, Junko Takei, Takuro Nakamura, Ren Nanamiya, Hideki Hosono, Tomohiro Tanaka, Masato Sano, Hiroyuki Harada, Manabu Kawada, Mika K. Kaneko, Yukinari Kato
Article Number: 173
Published online on: 28 June 2021

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Article Open Access

Upregulation of TRIP13 promotes the malignant progression of lung cancer via the EMT pathway

Rujian Lu, Qian Zhou, Linling Ju, Lin Chen, Feng Wang, Jianguo Shao
Article Number: 172
Published online on: 28 June 2021

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Article Open Access

Endothelin-1 induces changes in the expression levels of steroidogenic enzymes and increases androgen receptor and testosterone production in the PC3 prostate cancer cell line

María José Torres, Fernanda López-Moncada, Daniela Herrera, Sebastián Indo, Alejandro Lefian, Paola Llanos, Julio Tapia, Enrique A. Castellón, Héctor R. Contreras
Article Number: 171
Published online on: 23 June 2021

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Article Open Access

Combining selective inhibitors of nuclear export (SINEs) with chimeric antigen receptor (CAR) T cells for CD19‑positive malignancies

Sanmei Wang, Leopold Sellner, Lei Wang, Tim Sauer, Brigitte Neuber, Wenjie Gong, Sophia Stock, Ming Ni, Hao Yao, Christian Kleist, Anita Schmitt, Carsten Müller‑Tidow, Michael Schmitt, Maria-Luisa Schubert
Article Number: 170
Published online on: 23 June 2021

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Article

Egr‑1 inhibits colon cancer cell proliferation, migration and invasion via regulating CDKL1 at the transcriptional level

Shanshan Shao, Man Ju, Jiayun Lei, Xiangqian Lu, Hongzhi Li, Darui Wang, Chaofeng Xia
Article Number: 169
Published online on: 23 June 2021

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Article Open Access

Nuclear IGF1R interacts with NuMA and regulates 53BP1‑dependent DNA double‑strand break repair in colorectal cancer

Chen Yang, Yifan Zhang, Nelly Segar, Changhao Huang, Pengwei Zeng, Xiangzhou Tan, Linfeng Mao, Zhikang Chen, Felix Haglund, Olle Larsson, Zihua Chen, Yingbo Lin
Article Number: 168
Published online on: 22 June 2021

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Article

MicroRNA‑10b modulates cisplatin tolerance by targeting p53 directly in lung cancer cells

Chen-Chu Lin, Wan-Ting Liao, Tsung-Ying Yang, Hsueh-Ju Lu, Shih-Lan Hsu, Chun-Chi Wu
Article Number: 167
Published online on: 22 June 2021

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Article Open Access

Dehydrocrenatidine extracted from Picrasma quassioides induces the apoptosis of nasopharyngeal carcinoma cells through the JNK and ERK signaling pathways

Ming-Chang Hsieh, Yu-Sheng Lo, Yi-Ching Chuang, Chia-Chieh Lin, Hsin-Yu Ho, Ming-Ju Hsieh, Jen-Tsun Lin
Article Number: 166
Published online on: 18 June 2021

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Article Open Access

Long noncoding RNA SLC9A3‑AS1 increases E2F6 expression by sponging microRNA‑486‑5p and thus facilitates the oncogenesis of nasopharyngeal carcinoma

Jiansheng Li, Dongzhi Li, Xianhua Zhang, Cuijuan Li, Fengjuan Zhu
Article Number: 165
Published online on: 17 June 2021

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Article Open Access

Long non‑coding RNA 00858 knockdown alleviates bladder cancer via regulation of the miR‑3064‑5p/CTGF axis

Ji Huang, Qiu-Ming He, Qi Wu, Wei-Min Zhou, Chao Hao, Gong-Xian Wang, Xin-Hua Tu
Article Number: 164
Published online on: 16 June 2021

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Article Open Access

METTL3‑mediated m6A modification of Bcl‑2 mRNA promotes non‑small cell lung cancer progression Corrigendum in /10.3892/or.2023.8502

Yongxi Zhang, Shuyuan Liu, Tiesuo Zhao, Chengxue Dang
Article Number: 163
Published online on: 15 June 2021

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Article

miR‑375/Yes‑associated protein axis regulates IL‑6 and TGF‑β expression, which is involved in the cisplatin‑induced resistance of liver cancer cells

Kanru Yu, Hao Li, Zhongyi Jiang, Han-Jen Hsu, Hsing-Chun Hsu, Yumei Zhang, Kunwei Wang
Article Number: 162
Published online on: 14 June 2021

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Retraction Open Access

[Retracted] miR‑154 targeting ZEB2 in hepatocellular carcinoma functions as a potential tumor suppressor

Xiaoli Pang, Kexin Huang, Qianqian Zhang, Yujiao Zhang, Junqi Niu
Article Number: 161
Published online on: 14 June 2021

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Review

Association between oral microflora and gastrointestinal tumors (Review)

Xiaoxiao Li, Sibo Zhu, Tiejun Zhang, Xingdong Chen
Article Number: 160
Published online on: 10 June 2021

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Correction Open Access

[Corrigendum] TOOLBOX: Strep‑Tagged nano‑assemblies of antibody‑drug‑conjugates (ADC) for modular and conditional cancer drugging

Elisa Tremante, Leonardo Sibilio, Fabio Centola, Nadine Knutti, Gerd Holzapfel, Isabella Manni, Matteo Allegretti, Paolo Lombardi, Giuseppe Salvo, Loredana Cecchetelli, Karlheinz Friedrich, Joachim Bertram, Patrizio Giacomini
Article Number: 159
Published online on: 09 June 2021

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Review

The role of immunotherapy and molecular‑targeted therapy in the treatment of melanoma (Review)

Paulina Stachyra‑Strawa, Marzanna Ciesielka, Michał Janiszewski, Ludmiła Grzybowska‑Szatkowska
Article Number: 158
Published online on: 09 June 2021

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Article

RHBDD2‑WWOX protein interaction during proliferative and differentiated stages in normal and breast cancer cells

Valeria Alejandra Ferretti, Romina Canzoneri, Sabina Palma, Ezequiel Lacunza, Claudio Marcelo Aldaz, Martín Carlos Abba
Article Number: 157
Published online on: 08 June 2021

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Retraction Open Access

[Retracted] MicroRNA-124 suppresses the migration and invasion of osteosarcoma cells via targeting ROR2-mediated non-canonical Wnt signaling

Can Zhang, Yihe Hu, Jun Wan, Hongbo He
Article Number: 156
Published online on: 07 June 2021

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Retraction Open Access

[Retracted] MicroRNA-205 acts as a tumor suppressor in osteosarcoma via targeting RUNX2

Can Zhang, Feng Long, Jun Wan, Yihe Hu, Hongbo He
Article Number: 155
Published online on: 07 June 2021

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Article

RUNX2/miR‑31/SATB2 pathway in nickel‑induced BEAS‑2B cell transformation

Yusha Zhu, Qiao Yi Chen, Ashley Jordan, Hong Sun, Nirmal Roy, Max Costa
Article Number: 154
Published online on: 07 June 2021

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Article

Heterogeneous nuclear ribonucleoprotein A2/B1 regulates the ERK and p53/HDM2 signaling pathways to promote the survival, proliferation and migration of non‑small cell lung cancer cells

Min Kyu Kim, Mun Ju Choi, Hyun Min Lee, Hong Seo Choi, Young-Kwon Park, Chun Jeih Ryu
Article Number: 153
Published online on: 07 June 2021

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Retraction Open Access

[Retracted] miR‑133a inhibits cervical cancer growth by targeting EGFR

Xuesong Song, Bo Shi, Kexin Huang, Wenjie Zhang
Article Number: 152
Published online on: 02 June 2021

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Journal Cover
April-2026 Volume 55 Issue 4

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

KDM5D expression is lost in cisplatin‑resistant neuroblastoma cells

Natalia Podhorska, Jan Hrabeta, Marie Belhajova, Tomas Eckschlager
Article Number: 79
Published online on: 25 February 2026

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Article Open Access

Role of iron and TfR1 in the application of high‑dose ascorbate against pancreatic cancer

Alban Piotrowsky, Christian Leischner, Hendrik Schmieder, Katja Detert, Kathrin Schneider, Johanna Schulte, Sabrina Hammerschmidt, Luigi Marongiu, Olga Renner, Markus Burkard, Sascha Venturelli
Article Number: 78
Published online on: 24 February 2026

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Review Open Access

Advances in immunotherapy and targeted therapy for nasopharyngeal carcinoma: Current progress and combined approaches (Review)

Zhen Yang, Huajun Liu, Meilin Chen, Liming Zhang, Meiling Gong, Ruilian Yu
Article Number: 77
Published online on: 24 February 2026

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Retraction Open Access

[Retracted] Overexpression of SHP2 tyrosine phosphatase promotes the tumorigenesis of breast carcinoma

Zhongqian Hu, Haoshu Fang, Xinyi Wang, Danlei Chen, Zhuo Chen, Siying Wang
Article Number: 76
Published online on: 24 February 2026

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Article Open Access

NR4A1 mediates chemotherapy‑induced senescence via the PI3K/AKT pathway in gastric cancer cells

Tingyu Zhang, Yue Wang, Jiuna Zhang, Xueshuai Ye, Yanfeng Shen, Zhiwei Zhang
Article Number: 75
Published online on: 18 February 2026

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Article

Hypoxia‑induced miR‑135b‑5p promotes neuroendocrine differentiation of prostate cancer cells through HIF1AN‑HIF1α axis

Pampana Sandhya Venkata Lakshmi, Jagrati Parashar, Biswajit Biswas, Ramesh Ummanni
Article Number: 74
Published online on: 16 February 2026

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Retraction Open Access

[Retracted] Knockdown of human antigen R reduces the growth and invasion of breast cancer cells in vitro and affects expression of cyclin D1 and MMP‑9

Zhu Yuan, Andrew J. Sanders, Lin Ye, Yu Wang, Wen G. Jiang
Article Number: 73
Published online on: 16 February 2026

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Review Open Access

Liquid biopsy in malignant primary bone tumors: Clinical applications of circulating tumor DNA and circulating tumor cells for diagnosis, prognosis and treatment monitoring (Review)

Bin Tian, Xuesong Chen, Jiang Zheng, Xin Kang
Article Number: 72
Published online on: 12 February 2026

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Article Open Access

Tumor visualization and evaluation of glioblastoma in mice using small animal 9.4T MRI and PET‑CT with high resolution

Shuangyi Li, Wenjiao Gu, Ying Jiang, Ting Liu, Limei Shuai, Yujie Wei, Youming Shi, Havyarimana Juvenal, Zhimin Wang, Yucai Wei, Bofan Wu, Xiaochun Zhou, Yumin Li, Futian Tang
Article Number: 71
Published online on: 12 February 2026

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Expression of Concern Open Access

[Expression of Concern] Interference of STAT 5b expression enhances the chemo‑sensitivity of gastric cancer cells to gefitinib by promoting mitochondrial pathway‑mediated cell apoptosis

Tao Sun, Yanfei Jia, Dongjie Xiao
Article Number: 70
Published online on: 11 February 2026

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Article Open Access

Regorafenib and Nifuroxazide exert enhanced suppression of hepatocellular carcinoma by inhibiting STAT3 and immune remodeling

Kun Li, Jinwei Chen, Zhi Zheng, Yichun Gao, Jiayu Zhang, Wenya Ding, Tongguo Yang, Yuyang Gu, Xuhua Duan, Tiesuo Zhao, Huijie Jia, Pengfei Chen, Jianzhuang Ren
Article Number: 69
Published online on: 11 February 2026

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Article Open Access

Suppressive role of SCN4B in the epithelial‑mesenchymal transition of lung adenocarcinoma

Mengnan Guo, He Li, Zhifang Zhao, Yuanyuan Wang, Jiaqi Tang, Binghan Zhong, Yunxia Zhao
Article Number: 68
Published online on: 10 February 2026

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Retraction Open Access

[Retracted] miR‑218 suppresses cardiac myxoma proliferation by targeting myocyte enhancer factor 2D

Quanxing Cao, Pingshuan Dong, Yanyu Wang, Junwei Zhang, Xinge Shi, Yongsheng Wang
Article Number: 67
Published online on: 09 February 2026

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Review

Impact of the intratumoral resident microbiome on the immune microenvironment of malignant tumors (Review)

Han Na Oh, Hoon Hur
Article Number: 66
Published online on: 06 February 2026

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Correction Open Access

[Corrigendum] Hypoxia and macrophages promote glioblastoma invasion by the CCL4‑CCR5 axis

Ying Wang, Tao Liu, Ning Yang, Shuo Xu, Xingang Li, Donghai Wang
Article Number: 65
Published online on: 04 February 2026

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Review Open Access

Origin dictates function: The dual roles of exosomes derived from diverse origins in the onset and progression of colorectal cancer (Review)

Zhao Guo, Haoyan Zhuang, Qingfeng Liu
Article Number: 64
Published online on: 03 February 2026

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Article Open Access

Quercetin reduces expression of ATP‑binding cassette transporters by regulating the PTEN/PI3K/AKT signaling pathway in breast cancer cells

Wentao Fu, Leying Lin, Jie Li, Fei Qin, Chuan Chen, Yinglian Cai, Yilun Cai, Yiling Huang, Wang Yang, Shanshan Zhu
Article Number: 63
Published online on: 02 February 2026

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Article Open Access

POSTN+ fibroblast‑secreted small extracellular vesicles drive macrophage M2 polarization through BMP4/BMPR2/Smad signaling

Chenyang Zhang, Si Chen, Chenghui Qian, Wanqi Lv, Qian Zhang, Yanjin Wang, Yuqiong Wu, Xue Liu
Article Number: 62
Published online on: 02 February 2026

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Retraction Open Access

[Retracted] EGFR/HER2 inhibitors effectively reduce the malignant potential of MDR breast cancer evoked by P‑gp substrates in vitro and in vivo

Yiting Jin, Wei Zhang, Hongying Wang, Zijing Zhang, Chengyu Chu, Xiuping Liu, Qiang Zou
Article Number: 61
Published online on: 02 February 2026

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Article

Tumor‑associated glucocorticoid inhibition by mifepristone reduces polymorphonuclear myeloid‑derived suppressor cells and promotes antitumor immunity in triple‑negative breast cancer‑bearing mice

Masato Kobayashi, Chisana Konno, Ayato Shimizu, Masanori Kobayashi, Tatsuya Hori
Article Number: 60
Published online on: 30 January 2026

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Review Open Access

Mitochondria in T‑cell tumor immunity and tumor therapies targeting mitochondria (Review)

Minjie Zhou, Yijie Xie, Zhipeng Liu, Yi He, Yibing Yin, Keyu Chen, Zhengyu Zhao, Chengshun Zhang, Dingjun Cai
Article Number: 59
Published online on: 29 January 2026

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Article Open Access

TRIM46 deficiency‑induced DNA damage enhances the sensitivity of cisplatin in non‑small cell lung cancer by regulating the Akt signaling pathway

Song Jin, Dandan Zhang, Zhicheng Liao, Lingpei Yu, Yuanyuan Wang, Pengcheng Jia, Minmin Pan, Yifan Li, Jizhou Zhang
Article Number: 58
Published online on: 28 January 2026

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Review Open Access

Advances in isolation and detection technologies and immunotherapy applications of circulating tumor cells (Review)

Ping Zhou, Qin Ye, Yiyun Huang, Yumei Feng, Li Zhou, Ke Xie
Article Number: 57
Published online on: 28 January 2026

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Correction Open Access

[Corrigendum] 3‑Bromopyruvate sensitizes human breast cancer cells to TRAIL‑induced apoptosis via the phosphorylated AMPK‑mediated upregulation of DR5

Yuzhong Chen, Li Wei, Xiaojing Zhang, Xianfu Liu, Yansong Chen, Song Zhang, Lanzhu Zhou, Qixiang Li, Qiong Pan, Surong Zhao, Hao Liu
Article Number: 56
Published online on: 28 January 2026

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Article Open Access

High RMI1 expression is associated with cancer cell progression and poor prognosis in prostate cancer

Pengliang Shen, Xiaosong Wang, Xiaoting Yan, Hongyang Du, Bo Wu, Xiaoming Cao
Article Number: 55
Published online on: 27 January 2026

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Retraction Open Access

[Retracted] MicroRNA‑615‑5p targets insulin‑like growth factor 2 and exerts tumor‑suppressing functions in human esophageal squamous cell carcinoma

Bingyin Yang, Rui Xie, Shang-Nong Wu, Cheng-Cheng Gao, Xiao-Zhong Yang, Jing-Fang Zhou
Article Number: 54
Published online on: 26 January 2026

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May-2026 Volume 55 Issue 5

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Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

Platycodin D sensitizes head and neck squamous cell carcinoma to cisplatin by inducing autophagy arrest

Minji Bae, Min Kyeong Lee, Mi Gyeong Jeong, Yeonseo Lee, Harim Joo, Young Chan Lee, Jung Woo Lee, Su Il Kim, Seong-Gyu Ko, Young-Gyu Eun
Article Number: 83
Published online on: 27 February 2026

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Article Open Access

ACSBG1‑driven lipid reprogramming unveiled: A fatty acid metabolism‑associated prognostic model for lung adenocarcinoma

Panxin Hu, Anan Li
Article Number: 82
Published online on: 27 February 2026

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Article Open Access

Knockdown of CCT2 inhibits the malignant progression of hepatocellular carcinoma cells by impairing STAT3 activation

Chao Li, Lei Yang, Yudong Zhang, Baocheng Zhao, Hao Qu
Article Number: 81
Published online on: 25 February 2026

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Retraction Open Access

[Retracted] Songorine suppresses cell growth and metastasis in epithelial ovarian cancer via the Bcl‑2/Bax and GSK3β/β‑catenin signaling pathways

Hongxia Zhang, Ruifeng Dong, Ping Zhang, Yankui Wang
Article Number: 80
Published online on: 25 February 2026

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