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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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International Journal of Molecular Medicine

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
February 2008 Volume 21 Issue 2

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article

A novel polymorphism, E254K, in the 5-lipoxygenase gene associated with bronchial asthma

Chunying Bai, Eiko Matsui, Hidenori Ohnishi, Kaori Kimata, Kimiko Kasahara, Hideo Kaneko, Zenichiro Kato, Toshiyuki Fukao, Naomi Kondo
Pages: 139-144
Published online on: 01 February 2008

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Article

CDC25A inhibition suppresses the growth and invasion of human hepatocellular carcinoma cells

Xundi Xu, Hirofumi Yamamoto, Guoxing Liu, Yasuhiro Ito, Chew Yee Ngan, Motoi Kondo, Hiroaki Nagano, Keizo Dono, Mitsugu Sekimoto, Morito Monden
Pages: 145-152
Published online on: 01 February 2008

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Article

Phosphorylation and nuclear translocation of STAT3 regulated by the Epstein-Barr virus latent membrane protein 1 in nasopharyngeal carcinoma

Yi-ping Liu, Yun-nian Tan, Zhen-lian Wang, Liang Zeng, Zhong-xin Lu, Li-li Li, Wei Luo, Min Tang, Ya Cao
Pages: 153-162
Published online on: 01 February 2008

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Article

Novel tubulin-polymerization inhibitor derived from thalidomide directly induces apoptosis in human multiple myeloma cells: Possible anti-myeloma mechanism of thalidomide

Toyotaka Iguchi, Tomomi Yachide-Noguchi, Yuichi Hashimoto, Sawako Nakazato, Morihiko Sagawa, Yasuo Ikeda, Masahiro Kizaki
Pages: 163-168
Published online on: 01 February 2008

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Article

Overexpression of human selenoprotein M differentially regulates the concentrations of antioxidants and H2O2, the activity of antioxidant enzymes, and the composition of white blood cells in a transgenic rat

Dae Youn Hwang, Ji Soon Sin, Min Sun Kim, Su Youn Yim, Yong Kyu Kim, Chuel Kyu Kim, Byoung Guk Kim, Sun Bo Shim, Seung Wan Jee, Su Hae Lee, Chang Joon Bae, Byoung Chun Lee, Mee Kyung Jang, Jung Sik Cho, Kab Ryong Chae
Pages: 169-179
Published online on: 01 February 2008

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Article

Allograft inflammatory factor-1 augments macrophage phagocytotic activity and accelerates the progression of atherosclerosis in ApoE−/− mice

Tetsuya Mishima, Kazuya Iwabuchi, Satoshi Fujii, Shin-ya Tanaka, Hisako Ogura, Keiko Watano-Miyata, Naoki Ishimori, Yasuhiro Andoh, Yukihito Nakai, Chikako Iwabuchi, Manabu Ato, Akira Kitabatake, Hiroyuki Tsutsui, Kazunori Onoé
Pages: 181-187
Published online on: 01 February 2008

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Article

Parental-origin-determination fluorescence in situ hybridization distinguishes homologous human chromosomes on a single-cell level

A. Weise, M. Gross, K. Mrasek, H. Mkrtchyan, B. Horsthemke, C. Jonsrud, F. Von Eggeling, S. Hinreiner, V. Witthuhn, U. Claussen, T. Liehr
Pages: 189-200
Published online on: 01 February 2008

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Reduced rate of adenosine triphosphate synthesis by in vivo 31P nuclear magnetic resonance spectroscopy and downregulation of PGC-1β in distal skeletal muscle following burn

A. Aria Tzika, Dionyssios Mintzopoulos, Katie Padfield, julie wilhelmy, Michael N. Mindrinos, Hongue Yu, Haihui Cao, Qunhao Zhang, Loukas G. Astrakas, Jiangwen Zhang, Yong-Ming Yu, Laurence G. Rahme, Ronald G. Tompkins
Pages: 201-208
Published online on: 01 February 2008

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Article

Induction of c-Myc-dependent cell proliferation through toll-like receptor 3 in head and neck cancer

Ralph Pries, Lisa Hogrefe, Lei Xie, Henning Frenzel, Carsten Brocks, Claudia Ditz, Barbara Wollenberg
Pages: 209-215
Published online on: 01 February 2008

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Article

GPI-anchorless human prion protein is secreted and glycosylated but lacks superoxide dismutase activity

Akikazu Sakudo, Izuru Nakamura, Shotaro Tsuji, Kazuyoshi Ikuta
Pages: 217-222
Published online on: 01 February 2008

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Aging and anti-aging: Unexpected side effects of everyday medication through sirtuin1 modulation

Nicole Engel, Ulrich Mahlknecht
Pages: 223-232
Published online on: 01 February 2008

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Article

Age-related changes in BAFF and APRIL profiles and upregulation of BAFF and APRIL expression in patients with primary antibody deficiency

Rong Jin, Hideo Kaneko, Hiroko Suzuki, Takahiro Arai, Takahide Teramoto, Toshiyuki Fukao, Naomi Kondo
Pages: 233-238
Published online on: 01 February 2008

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Article

Inhibition of experimental abdominal aortic aneurysm progression by nifedipine

Naruya Tomita, Keita Yamasaki, Keiko Izawa, Yasuo Kunugiza, Mariana k. Osako, Toshio Ogihara, Ryuichi Morishita
Pages: 239-244
Published online on: 01 February 2008

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Article

Tuberin-heterozygous cell line TSC2ang1 as a model for tuberous sclerosis-associated skin lesions

Pawel k. Wlodarski, Radoslaw Maksym, Monika Oldak, Sergiusz Jozwiak, Andrzej Wojcik, Jaroslaw Jozwiak
Pages: 245-250
Published online on: 01 February 2008

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Article

Quantitative RT-PCR assays for the determination of urokinase-type plasminogen activator and plasminogen activator inhibitor type 1 mRNA in primary tumor tissue of breast cancer patients: Comparison to antigen quantification by ELISA

Julia c. Biermann, Leon Holzscheiter, Matthias Kotzsch, Thomas Luther, Marion Kiechle-Bahat, Fred C.G.J. Sweep, Paul N. Span, Manfred Schmitt, Viktor Magdolen
Pages: 251-259
Published online on: 01 February 2008

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Article

Cancer genes induced by malathion and parathion in the presence of estrogen in breast cells

G. M. Calaf, D. Roy
Pages: 261-268
Published online on: 01 February 2008

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Journal Cover
March-2026 Volume 57 Issue 3

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

Ginkgolide C alleviates atherosclerosis via activating Nrf2 to inhibit ROS‑dependent NLRP3 inflammasome activation

Rui Zhang
Article Number: 75
Published online on: 27 January 2026

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Review Open Access

MicroRNA‑microbiome cross‑kingdom networks drive inflammatory bowel disease through dynamic regulatory ecosystems (Review)

Liping Liang, Xiaoyan Liu, Bang Li, Huyi Lei, Zibo Tang, Shijie Mai, Chenghai Yang, Yongjian Zhou, Shaoheng Zhang, Le Liu
Article Number: 74
Published online on: 27 January 2026

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Review Open Access

Mechanistic insights into pancreatic cancer progression from circadian rhythm disruption and gut microbiota dysbiosis (Review)

Yang Liu, Yongfeng Li, Heng Ma, Shichang Deng, Chao Cheng
Article Number: 73
Published online on: 26 January 2026

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Retraction Open Access

[Retracted] miR‑124‑3p inhibits the viability and motility of glioblastoma multiforme by targeting RhoG  

Shan Cai, Chao-Jia Shi, Jian-Xiang Lu, Yan-Pei Wang, Tian Yuan, Xiang-Peng Wang
Article Number: 72
Published online on: 26 January 2026

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Natural products as multi‑target therapies for sepsis‑induced myocardial dysfunction (Review)

Fei Tang, Dong Liu, Shi-Chao Zhu, Hui-Min Zhou, Xue-Wen Qiu
Article Number: 71
Published online on: 22 January 2026

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Review Open Access

MTHFR‑folate axis as a modulator of the epigenetic landscape in autoimmune diseases (Review)

Pablo Michael Navarro‑Rodríguez, Ramón Francisco Bajeca‑Serrano, Francisco Javier Turrubiates‑Hernández, Hazael Ramiro Ceja‑Gálvez, Jorge Hernández‑Bello, Cristian Oswaldo Hernández‑Ramírez, Saúl Ramírez‑de Los Santos, José Francisco Muñoz‑Valle
Article Number: 70
Published online on: 22 January 2026

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Article Open Access

Natural compound 5,7,8‑trimethoxyflavone mitigates radiation‑induced lung injury by suppressing EMT and PI3K/Akt pathway

Cui-Cui Gong, Hua-Kang Li, Yuan-Zhen Mi, Jun-Yang Chen, Zeng-Yi Fang, Shun-Lian Fu, Li Quan, Bing Lin, Jin-Yi Lang, Qiu Chen, Ke Xu, Mei-Hua Chen
Article Number: 69
Published online on: 21 January 2026

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Review Open Access

Epigenetic dysregulation of B‑cells in autoimmune diseases and lymphomas (Review)

Yuxing Li, Yujiao Gong, Jiaxing Zhao, Rensen Ran
Article Number: 68
Published online on: 21 January 2026

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Review Open Access

Research progress on the effects of macrophage‑derived exosomes on muscle factors IGF‑1 and FGF‑2 mediating musculoskeletal crosstalk molecular signaling pathway on bone metabolism (Review)

Ruo-Mei Cui, Mai Zheng, Jian-Bin Hong, Zheng-Xiang Wang, Yu-Fang Cun, Shu-Ji Gao, Yan-Lin Zhu, Zi-Bin Yang, Ming-Wei Liu
Article Number: 67
Published online on: 21 January 2026

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Expression of Concern Open Access

[Expression of Concern] Long non‑coding RNA SNHG20 promotes bladder cancer via activating the Wnt/β‑catenin signalling pathway

Qingsong Zhao, Saiyue Gao, Qingyan Du, Ye Liu
Article Number: 66
Published online on: 21 January 2026

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Mangiferin in human disease: Multifaceted mechanisms and applications (Review)

Yaling Dai, Qiuling Huang, Mengquan Tan, Zhifu Wang, Cai Jiang, Zheng Liu, Shenghang Zhang, Siyuan Song
Article Number: 65
Published online on: 21 January 2026

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Article

Deciphering the CAF‑LCN2 axis: Key to overcoming anti‑PD‑L1 immunotherapy resistance in lung cancer

Dan Xiao, Jing Yang, Jianying Zhou, Zhenzhen Hu, Ting Zhang
Article Number: 64
Published online on: 19 January 2026

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Retraction Open Access

[Retracted] DDAH2 alleviates myocardial fibrosis in diabetic cardiomyopathy through activation of the DDAH/ADMA/NOS/NO pathway in rats

Zhen-Dong Zhu, Ji-Ming Ye, Xue-Mei Fu, Xue-Chang Wang, Ji-Yun Ye, Xin-Ran Wu, Peng Hua, Yu-Qiong Liao, Wei Xuan, Jin-Lan Duan, Wei-Yuan Li, Hui Fu, Zhong-Hua Xia, Xuan Zhang
Article Number: 63
Published online on: 19 January 2026

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Review Open Access

Beyond hepatic stellate cell heterogeneity: Resolving fibrosis, restoring regeneration (Review)

Chang Gao, Guiqing Chen, Hongyan Jia, Hong Zhu, Yun Cai, Dakai Yang, Kai Zhao
Article Number: 62
Published online on: 14 January 2026

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Correction Open Access

[Corrigendum] CDKN2A (p16INK4A) affects the anti‑tumor effect of CDK inhibitor in somatotroph adenomas

Yiyuan Chen, Zhenye Li, Qiuyue Fang, Hongyun Wang, Chuzhong Li, Hua Gao, Yazhuo Zhang
Article Number: 61
Published online on: 14 January 2026

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Review Open Access

Harnessing MSC‑derived exosomes to modulate the pathophysiology of ASD: Recent advances and therapeutic implications (Review)

Zhaojian Sun, Nouman Amjad, Majid Muhammad, Zhiyuan Li
Article Number: 60
Published online on: 13 January 2026

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Retraction Open Access

[Retracted] Mechanism of cell death induced by silica nanoparticles in hepatocyte cells is by apoptosis

Ye Yang, Xinjing Du, Qiang Wang, Jianwei Liu, Enguo Zhang, Linlin Sai, Cheng Peng, Martin F. Lavin, Abrey Jie Yeo, Xu Yang, Hua Shao, Zhongjun Du
Article Number: 59
Published online on: 12 January 2026

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Review Open Access

ZG16B: A key regulator of tumor progression and immune microenvironment modulation in cancer (Review)

Xing-Ming Chen, Yu-Bo Liang, Jin-Xiang Zuo, Zi-Sheng Yang, Le-Yu Zhang, Xin-Yu Zhang, Ping Wan, Yang Ke
Article Number: 58
Published online on: 09 January 2026

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Retraction Open Access

[Retracted] Silica nanoparticles induce cardiomyocyte apoptosis via the mitochondrial pathway in rats following intratracheal instillation

Zhongjun Du, Shangya Chen, Guanqun Cui, Ye Yang, Enguo Zhang, Qiang Wang, Martin F. Lavin, Abrey J. Yeo, Cunxiang Bo, Yu Zhang, Chao Li, Xiaoshan Liu, Xu Yang, Cheng Peng, Hua Shao
Article Number: 57
Published online on: 05 January 2026

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Role of cuproptosis in digestive system tumors (Review)

Li Zhang, Yongpeng Cheng, Lulu Tang, Jiaxing Zhu, Biguang Tuo
Article Number: 56
Published online on: 02 January 2026

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Review Open Access

Environmental exposure to air pollution and climate: Intersecting the impact on ear and nose health and chemosensory function (Review)

Yu-Chen Zhang, Lei Zhang, Ping-Ting Zhou, Zi-Hui Xie, Wen-Jie Zhang, Min Fan, Yan-Xun Han, Ye-Hai Liu, Yu-Chen Liu
Article Number: 55
Published online on: 31 December 2025

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Review Open Access

Role and mechanisms of ferroptosis in cognitive impairment: From molecular pathways to therapeutic targets (Review)

Shenghui Ge, Deyue Kong, Shuyue Fan, Yi Luo, Xiao Yin, Zehua Jin, Wenqing Xia, Jianhua Ma
Article Number: 54
Published online on: 30 December 2025

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Review Open Access

The GPR124‑Wnt‑PPARγ regulatory axis: Molecular mechanisms and therapeutic implications in chronic inflammatory diseases (Review)

Ming-Wang Cui, Si-Yu Tao, Tao Wen, Zhu-Ling Guo
Article Number: 53
Published online on: 30 December 2025

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Review Open Access

Advances in RPGR gene therapy for X‑linked retinitis pigmentosa: From preclinical insights to clinical application (Review)

Yushan Long, Jia Qi, Wenliang Zhang, Huan Qin, Kai Yao
Article Number: 52
Published online on: 30 December 2025

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Journal Cover
April-2026 Volume 57 Issue 4

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Immunological mechanisms and novel therapeutic strategies for sepsis‑associated acute kidney injury (Review)

Lu Xu, Wei Jiang, Lin Song, Jing Wang, Jiangquan Yu, Ruiqiang Zheng
Article Number: 78
Published online on: 30 January 2026

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Correction Open Access

[Corrigendum] Role of Smad3 signaling in the epithelial‑mesenchymal transition of the lens epithelium following injury

Fanlan Meng, Jun Li, Xiao Yang, Xiaoyong Yuan, Xin Tang
Article Number: 77
Published online on: 29 January 2026

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Review Open Access

Spatial metabolomics: A new tool for unravelling the metabolic disorders and heterogeneity in diabetic kidney disease (Review)

Hanfei Li, Yuxi Li, Bo Zhang, Wenhao Cheng, Guowei Ma, Jin Rong, Shiru Duan, Di Feng, Tingting Zhao
Article Number: 76
Published online on: 29 January 2026

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