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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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International Journal of Molecular Medicine

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
April-2015 Volume 35 Issue 4

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

The role of hypoxia in inflammatory disease (Review)

John Biddlestone, Daniel Bandarra, Sonia Rocha
Pages: 859-869
Published online on: 27 January 2015

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Article Open Access

Role of Drosophila EDEMs in the degradation of the alpha-1-antitrypsin Z variant

Bo-Yun Jang, Hyung Don Ryoo, Jaekyoung Son, Kyung-Chul Choi, Dong-Myoung Shin, Sang-Wook Kang, Min-Ji Kang
Pages: 870-876
Published online on: 25 February 2015

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Article Open Access

MicroRNA profiles following metformin treatment in a mouse model of non-alcoholic steatohepatitis

Akiko Katsura, Asahiro Morishita, Hisakazu Iwama, Joji Tani, Teppei Sakamoto, Miwa Tatsuta, Yuka Toyota, Koji Fujita, Kiyohito Kato, Emiko Maeda, Takako Nomura, Hisaaki Miyoshi, Hirohito Yoneyama, Takashi Himoto, Shintaro Fujiwara, Hideki Kobara, Hirohito Mori, Toshiro Niki, Masafumi Ono, Mitsuomi Hirashima, Tsutomu Masaki
Pages: 877-884
Published online on: 06 February 2015

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Article Open Access

Lentivirus-mediated RNAi knockdown of the gap junction protein, Cx43, attenuates the development of vascular restenosis following balloon injury

Xiao-Jian Han, Min Chen, Tao Hong, Ling-Yu Zhu, Dan  He, Jiu-Geng Feng, Li-Ping Jiang
Pages: 885-892
Published online on: 23 January 2015

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Article Open Access

Effects of miRNA-455 on cardiac hypertrophy induced by pressure overload

Chuntao Wu, Shimin Dong, Yongjun Li
Pages: 893-900
Published online on: 18 February 2015

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Article Open Access

Effects of baicalin on collagen Ι and collagen ΙΙΙ expression in pulmonary arteries of rats with hypoxic pulmonary hypertension

Panpan Liu, Shuangquan Yan, Mayun Chen, Ali Chen, Dan Yao, Xiaomei Xu, Xueding Cai, Liangxing Wang, Xiaoying Huang
Pages: 901-908
Published online on: 25 February 2015

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Article Open Access

The proliferative effects of Pyropia yezoensis peptide on IEC-6 cells are mediated through the epidermal growth factor receptor signaling pathway

Min-Kyeong Lee, In-Hye Kim, Youn-Hee Choi, Jeong-Wook Choi, Young-Min Kim, Taek-Jeong Nam
Pages: 909-914
Published online on: 26 February 2015

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Article Open Access

An ethanol root extract of Cynanchum wilfordii containing acetophenones suppresses the expression of VCAM-1 and ICAM-1 in TNF-α-stimulated human aortic smooth muscle cells through the NF-κB pathway

Hyun Jung Koo, Eun-Hwa Sohn, Suhkneung Pyo, Han Goo Woo, Dae Won Park, Young-Min Ham, Seon-A Jang, Soo-Yeong Park, Se Chan Kang
Pages: 915-924
Published online on: 26 February 2015

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Article Open Access

Effect of bombesin receptor subtype-3 and its synthetic agonist on signaling, glucose transport and metabolism in myocytes from patients with obesity and type 2 diabetes

Nieves González, Antonio Martín-Duce, Félix Martínez-Arrieta, Zaida Moreno-Villegas, Sergio Portal-Núñez, Raúl Sanz, Jesús Egido
Pages: 925-931
Published online on: 04 February 2015

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Article Open Access

Palmitate induces endoplasmic reticulum stress and autophagy in mature adipocytes: Implications for apoptosis and inflammation

Jiajing Yin, Yufan Wang, Liping Gu, Nengguang Fan, Yuhang Ma, Yongde Peng
Pages: 932-940
Published online on: 30 January 2015

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Article Open Access

CAP1 is overexpressed in human epithelial ovarian cancer and promotes cell proliferation

Minhui Hua, Sujuan Yan, Yan Deng, Qinghua Xi, Rong Liu, Shuyun Yang, Jian Liu, Chunhui Tang, Yingying Wang, Jianxin Zhong
Pages: 941-949
Published online on: 04 February 2015

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Article Open Access

Characterization of three alternative transcripts of the BRCA1 gene in patients with breast cancer and a family history of breast and/or ovarian cancer who tested negative for pathogenic mutations

Gaetana Gambino, Mariella Tancredi, Elisabetta Falaschi, Paolo Aretini, Maria Adelaide Caligo
Pages: 950-956
Published online on: 16 February 2015

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Article Open Access

Purple perilla extracts with α-asarone enhance cholesterol efflux from oxidized LDL-exposed macrophages

Sin-Hye Park, Ji Hun Paek, Daekeun Shin, Jae-Yong Lee, Soon Sung Lim, Young-Hee Kang
Pages: 957-965
Published online on: 12 February 2015

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Article

Enhanced expression of centromere protein F predicts clinical progression and prognosis in patients with prostate cancer

Yang-Jia Zhuo, Ming Xi, Yue-Ping Wan, Wei Hua, Yuan-Ling Liu, Song Wan, Yu-Lin Zhou, Hong-Wei Luo, Shu-Lin Wu, Wei-De Zhong, Chin-Lee Wu
Pages: 966-972
Published online on: 30 January 2015

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Article

Chromatin immunoprecipitation-sequencing predicts p300 binding sites in the MCF7 human breast cancer cell line Corrigendum in /10.3892/ijmm.2016.2642

Xiemei Wang, Shaolin Li
Pages: 973-978
Published online on: 27 January 2015

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Article

Melatonin improves experimental colitis with sleep deprivation

Young-Sook Park, Sook-Hee Chung, Seong-Kyu Lee, Ja-Hyun Kim, Jun-Bong Kim, Tae-Kyun Kim, Dong-Shin Kim, Haing-Woon Baik
Pages: 979-986
Published online on: 27 January 2015

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Article

Rhododendron album Blume inhibits iNOS and COX-2 expression in LPS-stimulated RAW264.7 cells through the downregulation of NF-κB signaling

Ji-Won Park, Ok-Kyoung Kwon, Jung-Hee Kim, Sei-Ryang Oh, Jae-Hong Kim, Jin-Hyub Paik, Bambang Marwoto, Rifatul Widjhati, Fifit Juniarti, Doddy Irawan, Kyung-Seop Ahn
Pages: 987-994
Published online on: 25 February 2015

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Article

PLGA/poloxamer nanoparticles loaded with EPAS1 siRNA for the treatment of pancreatic cancer in vitro and in vivo Retraction in /10.3892/ijmm.2024.5459

Xinting Pan, Qingyun Zhu, Yunbo Sun, Liandi Li, Yunpeng Zhu, Zhihui Zhao, Jianxin Zuo, Wei Fang, Kun Li
Pages: 995-1002
Published online on: 11 February 2015

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Article

The role of Toll-like receptor 3 and 4 in regulating the function of mesenchymal stem cells isolated from umbilical cord

Li Zhang, Dan Liu, Dan Pu, Yanwen Wang, Li Li, Yanqi He, Yalun Li, Lei Li, Zhixin Qiu, Shuang Zhao, Weimin Li
Pages: 1003-1010
Published online on: 19 February 2015

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Article

Berberine regulates melanin synthesis by activating PI3K/AKT, ERK and GSK3β in B16F10 melanoma cells

Young Chan Song, Yonghee Lee, Hyeong Mi Kim, Moo Yeol Hyun, Yun Young Lim, Kye Yong Song, Beom Joon Kim
Pages: 1011-1016
Published online on: 26 February 2015

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Article

Epidermal growth factor improves the migration and contractility of aged fibroblasts cultured on 3D collagen matrices

Daehwan Kim, So Young Kim, Seog Kyun Mun, Sangmyung Rhee, Beom Joon Kim
Pages: 1017-1025
Published online on: 03 February 2015

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Article

Sodium tanshinone IIA sulfonate attenuates the transforming growth factor-β1-induced differentiation of atrial fibroblasts into myofibroblasts in vitro

Le Yang, Jin Hu, Hong-Zhen Hao, Zhao Yin, Gang Liu, Xiao-Jing Zou
Pages: 1026-1032
Published online on: 02 February 2015

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Article

Downregulation of microRNA-1 in esophageal squamous cell carcinoma correlates with an advanced clinical stage and its overexpression inhibits cell migration and invasion

Li Yao, Yi Zhang, Qiao Zhu, Xinyi Li, Shaojun Zhu, Li Gong, Xiujuan Han, Miao Lan, Shanqu Li, Wei Zhang, Yanhong Li
Pages: 1033-1041
Published online on: 09 February 2015

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Article

Resveratrol exerts growth inhibitory effects on human SZ95 sebocytes through the inactivation of the PI3-K/Akt pathway

So Young Kim, Moo Yeol Hyun, Kyung Chan Go, Christos C. Zouboulis, Beom Joon Kim
Pages: 1042-1050
Published online on: 12 February 2015

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Article

Transplantation of human umbilical cord-derived mesenchymal stems cells for the treatment of Becker muscular dystrophy in affected pedigree members

Pang Li, Kai Cui, Bo Zhang, Zhendan Wang, Yangyang Shen, Xiangyu Wang, Jianbo Zhang, Feng Tong, Sheng Li
Pages: 1051-1057
Published online on: 30 January 2015

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Article

TBX20 loss-of-function mutation contributes to double outlet right ventricle

Yun Pan, Rui Geng, Ning Zhou, Gui-Fen Zheng, Hong Zhao, Juan Wang, Cui-Mei Zhao, Xing-Biao Qiu, Yi-Qing Yang, Xing-Yuan Liu
Pages: 1058-1066
Published online on: 22 January 2015

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Article

Fucoidan exerts protective effects against diabetic nephropathy related to spontaneous diabetes through the NF-κB signaling pathway in vivo and in vitro

Yan Wang, Minghao Nie, Yanhong Lu, Rui Wang, Jin Li, Bin Yang, Mingyang Xia, Haiyang Zhang, Xiurong Li
Pages: 1067-1073
Published online on: 09 February 2015

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Article

Integrin-β1 regulates chondrocyte proliferation and apoptosis through the upregulation of GIT1 expression

Long-Qiang Zhang, Guang-Zong Zhao, Xiao-Yan Xu, Jun Fang, Jing-Ming Chen, Ji-Wen Li, Xue-Jian Gao, Li-Juan Hao, Yun-Zhen Chen
Pages: 1074-1080
Published online on: 26 February 2015

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Article

BAD-mediated apoptotic pathway is associated with human cancer development

Xiaomang B. Stickles, Douglas C. Marchion, Elona Bicaku, Entidhar Al Sawah, Forough Abbasi, Yin Xiong, Nadim Bou Zgheib, Bernadette M. Boac, Brian C. Orr, Patricia L. Judson, Amy Berry, Ardeshir Hakam, Robert M. Wenham, Sachin M. Apte, Anders E. Berglund, Johnathan M. Lancaster
Pages: 1081-1087
Published online on: 05 February 2015

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Article

Dual effect of metformin on growth inhibition and oestradiol production in breast cancer cells

S. Rice, L. Pellat, A. Ahmetaga, G. Bano, H. D. Mason, S. A. Whitehead
Pages: 1088-1094
Published online on: 25 February 2015

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Review

Mitogen-activated protein kinase phosphatase-1: A critical phosphatase manipulating mitogen-activated protein kinase signaling in cardiovascular disease (Review)

Chang-Yi Li, Ling-Chao Yang, Kai Guo, Yue-Peng Wang, Yi-Gang Li
Pages: 1095-1102
Published online on: 18 February 2015

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Article

Role of sphingosine-1-phosphate receptor 1 and sphingosine-1-phosphate receptor 2 in hyperglycemia-induced endothelial cell dysfunction

Shuhua Chen, Jie Yang, Hong Xiang, Wei Chen, Hua Zhong, Guoping Yang, Ting Fang, Hao Deng, Hong Yuan, Alex F. Chen, Hongwei Lu
Pages: 1103-1108
Published online on: 12 February 2015

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Article

Selective PCAF inhibitor ameliorates cognitive and behavioral deficits by suppressing NF-κB-mediated neuroinflammation induced by Aβ in a model of Alzheimer's disease

Soo-Yeon Park, Mi-Jeong Kim, Young Jun Kim, Yoo-Hyun Lee, Donghyuk Bae, Sunoh Kim, Younghwa Na, Ho-Geun Yoon
Pages: 1109-1118
Published online on: 12 February 2015

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Article

miR-29c is downregulated in the ectopic endometrium and exerts its effects on endometrial cell proliferation, apoptosis and invasion by targeting c-Jun

Mei Long, Xiaohui Wan, Xiaolin La, Xiaoyun Gong, Xia Cai
Pages: 1119-1125
Published online on: 27 January 2015

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Article

Saikosaponin a, an active compound of Radix Bupleuri, attenuates inflammation in hypertrophied 3T3-L1 adipocytes via ERK/NF-κB signaling pathways

Sung Ok Kim, Ji Yeoung Park, Seo Young Jeon, Chea Ha Yang, Mi Ryeo Kim
Pages: 1126-1132
Published online on: 06 February 2015

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Article

Qing Hua Chang Yin inhibits the LPS-induced activation of the IL-6/STAT3 signaling pathway in human intestinal Caco-2 cells

Xiao Ke, Guanghong Hu, Wenyi Fang, Jintuan Chen, Xin Zhang, Chunbo Yang, Jun Peng, Youqin Chen, Thomas J. Sferra
Pages: 1133-1137
Published online on: 28 January 2015

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Article

Successive passaging of the scrapie strains, ME7-ha and 139A-ha, generated by the interspecies transmission of mouse-adapted strains into hamsters markedly shortens the incubation times, but maintains their molecular and pathological properties

Qi Shi, Kang Xiao, Bao-Yun Zhang, Xiao-Mei Zhang, Li-Na Chen, Cao Chen, Chen Gao, Xiao-Ping Dong
Pages: 1138-1146
Published online on: 13 February 2015

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Correction Open Access

[Corrigendum] Alterations in gene expression during sexual differentiation in androgen receptor knockout mice induced by environmental endocrine disruptors

Dehong Liu, Liping Shen, Yonglin Tao, Ying Kuang, Lei Cai, Dan Wang, Meiduo He, Xuebo Tong, Shuguang Zhou, Jie Sun, Chenchen Shi, Chunxiao Wang, Yi Wu
Pages: 1147-1147
Published online on: 11 February 2015

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Journal Cover
June-2026 Volume 57 Issue 6

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article

Gilteritinib overcomes second‑generation TKIs resistance in ALK‑rearranged non‑small‑cell lung cancer by inhibiting PD‑L1 and CD8 co‑expression

Hang Guo, Yaoji Li, Chengyan Jin, Xiao Qi, Jincheng Wang, Baofeng Li, Chunguang Wang
Article Number: 168
Published online on: 28 April 2026

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Retraction Open Access

[Retracted] Metformin‑induced activation of AMPK inhibits the proliferation and migration of human aortic smooth muscle cells through upregulation of p53 and IFI16

Biao Hao, Yan Xiao, Fang Song, Xiangshu Long, Jing Huang, Maobo Tian, Shiyan Deng, Qiang Wu
Article Number: 167
Published online on: 22 April 2026

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Review Open Access

Dysregulation of the DNA repair‑immune axis: Targeted therapeutic strategies for autoimmune diseases (Review)

Ke Wan, Miao Wang, Qingqing Xia, Hui Fang, Ying Chen, Tongsheng Zhou, Xue Yang, Lu Wang, Jianwen Ye, Han Shu, Xiao-Feng Li, Jun Li
Article Number: 166
Published online on: 22 April 2026

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Retraction Open Access

[Retracted] Puerarin attenuates glucocorticoid‑induced apoptosis of hFOB1.19 cells through the JNK‑ and Akt‑mediated mitochondrial apoptotic pathways

Dongdong Yu, Shuai Mu, Danyang Zhao, Guangbin Wang, Zhiguang Chen, Hongfei Ren, Qin Fu
Article Number: 165
Published online on: 20 April 2026

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Review Open Access

High‑altitude polycythemia: Unveiling the molecular landscape beyond erythropoietin (Review)

Haiyan Li, Hongjuan Zhang, Hujun Zhang, Yujie Li, Yigang He, Jia Luan
Article Number: 164
Published online on: 17 April 2026

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Review

Mechanistic roles of interleukin‑18 in colonic immunity across infection, inflammatory bowel disease, and colorectal cancer (Review)

Jingwen Zhang, Lili Bao, Xia Li, Jiaxi Li, Jiaxian Cui, Lu Qiao, Xiaoxia He, Mingyu Zhang, Jingkun Lu, Xuan Zhang, Jing Dong, Gesi Tao, Tuya Bai, Yun Peng Tian, Pengwei Zhao, Ya Tuo
Article Number: 163
Published online on: 17 April 2026

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Article Open Access

IDH2 lactylation regulates mitochondrial dysfunction injury induced by myocardial ischemia‑reperfusion via the AMPK signaling pathway

Changsen Wang, Siman Shen, Suyun Chen, Jinda Lin, Simeng Li, Jianning Chen, Shuyun Cai, Xiaodong Yuan, Ziqiang Yang, Kun Ding, Li Xu, Liangqing Zhang
Article Number: 162
Published online on: 17 April 2026

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Review Open Access

Context‑dependent duality of the apelin/elabela‑APJ system in diabetes and its complications (Review)

Zhenyuan Han, Jiale Zhang, Min Shi, Juan Chen, Anni Li, Yuxuan Ye, Hong Zhang
Article Number: 161
Published online on: 17 April 2026

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Review Open Access

Glycolytic lactylation modulates cell death decisions in diabetic kidney disease: Metabolic‑epigenetic interplay between ferroptosis and autophagy in fibrotic remodeling (Review)

Taimin Zhang, Xizhe Zhang, Yaru Xie, Yue Liu, Siyu Xia, Xiaodie Yin, Tian Li, Libin Liao
Article Number: 160
Published online on: 16 April 2026

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Retraction Open Access

[Retracted] Quercetin promotes the apoptosis of fibroblast‑like synoviocytes in rheumatoid arthritis by upregulating lncRNA MALAT1

Fang Pan, Lihua Zhu, Haozhe Lv, Chunpeng Pei
Article Number: 159
Published online on: 15 April 2026

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Article Open Access

Triptolide exerts antiviral effects and alleviates influenza A‑induced pneumonia by inhibiting the overactivation of absent in melanoma 2 signaling in immune cells

Yeyang Chen, Hua Wu, Xiangjian Wu, Likun Che, Xiaoyan Fu, Ruihan Qi, Dan Jia, Minfang Li, Wei Xie, Wenxiang Zhu
Article Number: 158
Published online on: 15 April 2026

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Review Open Access

ETS‑1/ETS‑2 transcription factors in CVD (Review)

Shasha Yang, Jing Zhang, Ying Yang, Yunbo Lv, Jian Yang, Huibo Wang
Article Number: 157
Published online on: 15 April 2026

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Review Open Access

RNA‑binding proteins as epithelial transcriptome orchestrators in gastric cancer: Immune‑metabolic crosstalk and therapeutic vulnerability (Review)

Shuhui Liu, Zhiyuan Ma, Bei Ji, Jiaxing Zhu, Shun Yao, Shuji Terai, Biguang Tuo, Taolang Li, Xuemei Liu
Article Number: 156
Published online on: 14 April 2026

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Retraction Open Access

[Retracted] Role of miR‑146a in human chondrocyte apoptosis in response to mechanical pressure injury in vitro  

Lei Jin, Jian Zhao, Wensen Jing, Shiju Yan, Xin Wang, Chun Xiao, Baoan Ma
Article Number: 155
Published online on: 07 April 2026

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Review Open Access

A tale of dual role: HECT‑type E3 ubiquitin ligase mechanisms in liver diseases (Review)

Tongxi Li, Hao Chen, Peng Zhao, Chuanzheng Yin, Zifang Song
Article Number: 154
Published online on: 07 April 2026

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Correction Open Access

[Corrigendum] Macrophage‑derived foam cells impair endothelial barrier function by inducing endothelial‑mesenchymal transition via CCL‑4 

Ying Yang, Nian-Sang Luo, Ru Ying, Yong Xie, Jia-Yuan Chen, Xiao-Qiao Wang, Zhen-Jie Gu, Jing-Ting Mai, Wen-Hao Liu, Mao-Xiong Wu, Zhi-Teng Chen, Yong-Biao Fang, Hai-Feng Zhang, Zhi-Yi Zuo, Jing-Feng Wang, Yang-Xin Chen
Article Number: 153
Published online on: 03 April 2026

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Review Open Access

Macrophage metabolism reprogramming in sepsis: Pathogenesis and therapeutic implications (Review)

Tong Zhao, Wenzhe Zhang, Zixuan Ren, Xiujing Feng
Article Number: 152
Published online on: 03 April 2026

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Article Open Access

Astragaloside IV targets TUBB4B to inhibit proliferation and promote apoptosis of pituitary tumor cells via the STMN1/ERK pathway

Jiale Li, Yufei Qu, Wenge Zhang, Zexu Yang, Yangdong Zeng, Jisheng Xu, Kuncen Xie, Qi Liu
Article Number: 151
Published online on: 01 April 2026

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Expression of Concern Open Access

[Expression of Concern] Increased expression of heat shock protein 90 under chemical hypoxic conditions protects cardiomyocytes against injury induced by serum and glucose deprivation

Keng Wu, Wenming Xu, Qiong You, Runmin Guo, Jianqiang Feng, Changran Zhang, Wen Wu
Article Number: 150
Published online on: 01 April 2026

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Review Open Access

Animal models accurately representing acute liver failure (Review)

Sang Luo, Fang Wu, Yiran Jin, Xiaofen Huang, Dan Liu, Bingren Tian
Article Number: 149
Published online on: 01 April 2026

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Correction Open Access

[Corrigendum] Influence of aspirin on the CX3CL1/CX3CR1 signaling pathway in acute pulmonary embolism 

Zhirong Zhang, Weiji Yang, Rongbiao Ying, Ying Shi, Huifang Jiang, Danli Cai, Jing Kuang, Ruhui Yang, Lingcong Wang
Article Number: 148
Published online on: 31 March 2026

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Review Open Access

Targeting pyroptosis to treat aortic aneurysms: From mechanism to drug discovery (Review)

Jing Mao, Mandi Luo, Lei Ruan, Cuntai Zhang
Article Number: 147
Published online on: 31 March 2026

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Role of aging‑related cytokines in neurodegenerative disease (Review)

Xinke Dai, Xinran Rao, Yuandi Wang, Weijiang Zhao
Article Number: 146
Published online on: 31 March 2026

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Expression of Concern Open Access

[Expression of Concern] DTX3L is upregulated in glioma and is associated with glioma progression

Peng Xu, Xuelei Tao, Chengjin Zhao, Qingfeng Huang, Hao Chang, Na Ban, Yuanqi Bei, Xiaojie Xia, Chaoyan Shen, Kun Wang, Li Xu, Peizhang Wu, Jianbing Ren, Donglin Wang
Article Number: 145
Published online on: 30 March 2026

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Review Open Access

Role of itaconate in intestinal disease (Review)

Xin Li, Qian Liu, Jiajia Li, Li Zhang, Shun Yao, Lulu Tang, Bingqi Yang, Yongfeng Wang, Guorong Wen, Jiaxing An, Hai Jin, Biguang Tuo
Article Number: 144
Published online on: 27 March 2026

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Unveiling lactylation: A novel frontier in the pathogenesis of diabetic nephropathy (Review)

Yuanyuan Xiao, Niansong Wang, Dingkun Gui, Youhua Xu
Article Number: 143
Published online on: 27 March 2026

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Crosstalk between autophagy and ferroptosis in liver diseases (Review)

Yanming Wei, Kun Zhou, Yuerui Su, Zhihua Luan, Pengcheng Li, Yinxia Chang, Bo Han, Huifang Li, Yuanbiao Qiao, Jinhong Ren
Article Number: 142
Published online on: 26 March 2026

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Article Open Access

circOMA1 delivered by exosomes regulates DRD2‑mediated prolactinoma resistance

Qing Rao, Dimin Zhu, Zongming Wang, Shaolin Zhang, Xueli Li, Shashikiran Tagilapalli, Nan Wang, Weiyu Hu, Wenli Chen, Yonghong Zhu
Article Number: 141
Published online on: 26 March 2026

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Expression of Concern Open Access

[Expression of Concern] Involvement of Cyr61 in the growth, invasiveness and adhesion of esophageal squamous cell carcinoma cells

Jian-Jun Xie, Li-Yan Xu, Yang-Min Xie, Ze-Peng Du, Cai-Hua Feng, Hui Dong, En-Min Li
Article Number: 140
Published online on: 24 March 2026

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Article Open Access

Novel Hsp90 inhibitor JD‑02 inhibits HSV‑1 infection via the Raf/MEK/ERK signaling pathway

Yexuan Zhu, Xiaohui Wang, Jiaying Lin, Xiao Wang, Kai Zheng, Zhe Ren, Ji Xiao, Yifei Wang
Article Number: 139
Published online on: 24 March 2026

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July-2026 Volume 58 Issue 1

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Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

Hepatic p38γ exacerbates acetaminophen‑induced acute liver injury via PI3K/Akt‑dependent mechanisms

Hui Fang, Min Shu, Jiaju Wang, Heng Tian, Jianguo Zhang, Ying Hu, He Li, Huan Zhou, Kangsheng Gu, Zhenhua Ren
Article Number: 184
Published online on: 12 May 2026

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Pharmacological activity, molecular mechanisms and therapeutic potential of erianin (Review)

Chengyi Ming, Ni Zhu, You Yu, Hong Zhou, Meichun Hu
Article Number: 183
Published online on: 12 May 2026

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Rab27: Molecular switch of tumor exosome secretion (Review)

Mengtian Tang, Zhongjian Zhu, Huaxin Duan, Shiming Tan, Mengzhou Shen, Xianjie Jiang, Qiu Peng, Linda Oyang, Zongyao Ren, Yujuan Zhou, Qianjin Liao
Article Number: 182
Published online on: 12 May 2026

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IL‑17A+ γδT cell activation via the HMGB1‑TLR2/4‑NF‑κB signaling pathways in biliary atresia

Meng-Xin Zhang, Jing-Feng Tang, Mei Hong, Ying Yang, Yun Zhou, Shui-Qing Chi, Li-Ying Rong, Guo-Qing Cao, Xi Zhang, Jin-Xiang Zhang, Shao-Tao Tang
Article Number: 181
Published online on: 11 May 2026

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CircRAD18 promotes glioblastoma proliferation, migration and invasion via the miR‑1231/LUC7L2 axis

Lumeng Song, Ping Xiong, Amu Jike, Xiaochao Xia, Lifang Mao, Zihao Wang, Yinchuan Cheng, Shumin Wang, Shizheng Tan, Dongnan Yu, Zheng Li, Xiaoping Tang, Shun Li
Article Number: 180
Published online on: 11 May 2026

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[Corrigendum] Expression of FKBP52 in the ovaries of PCOS rats

Shiyan Song, Yong Tan
Article Number: 179
Published online on: 11 May 2026

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miR‑223‑3p promotes microglial lactylation and M1 polarization via the FBXW7/Notch1/Hes1/SIRT1 axis

Xiaoyu Wang, Lin Song, Jiafeng Wang, Qianqian Xie, Yan Wang, Chunyan Li, Tianqi Wang, Yifeng Du
Article Number: 178
Published online on: 08 May 2026

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Radiotherapy and cytokines: A systems view of immunotherapy and toxicity (Review)

Siyuan Zhou, Yurong Jiang, Jixu Fan, Minjie Guo, Yi Wen, Chunhua Dai
Article Number: 177
Published online on: 08 May 2026

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Advances in understanding the NLRP3 inflammasome‑mediated mechanisms and therapeutic targets in diabetic nephropathy (Review)

Xiwei Wang, Shuang Li, Xiaotian Ge, Tao Xie, Sainan Li, Ruiqi Yuan, Tianxi Li, Hui Yuan
Article Number: 176
Published online on: 06 May 2026

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Expression of Concern Open Access

[Expression of Concern] ISL1 promotes cancer progression and inhibits cisplatin sensitivity in triple‑negative breast cancer cells

Yang Zhang, Lu Wang, Peng Gao, Zhiguo Sun, Ning Li, Yanqin Lu, Jianglun Shen, Jian Sun, Yiming Yang, Hao Dai, Haifeng Cai
Article Number: 175
Published online on: 06 May 2026

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Phosphorylation beyond the plasma membrane: How secretory pathway kinases sculpt the cellular dialogue in cancer (Review)

Ziang Geng, Shu Guan, Shaoqi Du, Shuo Zhang, Jiaxin Hao, Siyuan Tian, Chen Zhu, Shaonan Du
Article Number: 174
Published online on: 06 May 2026

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Ferroptosis in musculoskeletal disorders: Emerging mechanisms and therapeutic opportunities (Review)

Wenhui Gu, Haifeng Zhang, Lisha Ye, Fangming Liu, Ting Xu, Yinxian Yu, Guohua Wang
Article Number: 173
Published online on: 05 May 2026

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Retraction Open Access

[Retracted] Regulation of p38 MAPK phosphorylation inhibits chondrocyte apoptosis in response to heat stress or mechanical stress

Ken Takebe, Takayuki Nishiyama, Shinya Hayashi, Shingo Hashimoto, Takaaki Fujishiro, Noriyuki Kanzaki, Kohei Kawakita, Kenjiro Iwasa, Ryosuke Kuroda, Masahiro Kurosaka
Article Number: 172
Published online on: 04 May 2026

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Dapagliflozin attenuates ferroptosis in diabetic nephropathy through activation of the Nrf2/HO‑1 signaling pathway

Hanshuang Liu, Xiaoxiao Zhang, Yubing Cui, Shengxi Xiong, Linjuan Huang, Min Li, Chen Shao, Xiaolei Hu
Article Number: 171
Published online on: 30 April 2026

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Article Open Access

Ligustroflavone protects against acute kidney injury by inhibiting ferroptosis via acting on GSK3β/NRF2 signaling

Jiayu Song, Long Wang, Yaru Wang, Jie Meng, Jingyi Sheng, Yongfeng Zhao, San Yan Xu, Juan Lei, Fangfang Cai, Yunwen Yang
Article Number: 170
Published online on: 30 April 2026

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Correction Open Access

[Corrigendum] Differential regulation of the biosynthesis of glucose transporters by the PI3‑K and MAPK pathways of insulin signaling by treatment with novel compounds from Liriope platyphylla

Yoen Kyung Lee, Ji Eun Kim, So Hee Nam, Jun Seo Goo, Sun Il Cho, Young Hwan Choi, Chang Jun Bae, Ong Min Woo, Jung Sik Cho, Dae Youn Hwang
Article Number: 169
Published online on: 28 April 2026

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