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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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International Journal of Molecular Medicine

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
October-2018 Volume 42 Issue 4

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Functions of EpCAM in physiological processes and diseases (Review)

Li Huang, Yanhong Yang, Fei Yang, Shaomin Liu, Ziqin Zhu, Zili Lei, Jiao Guo
Pages: 1771-1785
Published online on: 11 July 2018

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Review

Circular RNA, a novel marker for cancer determination (Review)

Yinjie Su, Guangzheng Zhong, Ning Jiang, Ming Huang, Tianxin Lin
Pages: 1786-1798
Published online on: 30 July 2018

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Article Open Access

TGM2 knockdown reverses cisplatin chemoresistance in osteosarcoma

Cuiyun Li, Jing Cai, Fugui Ge, Guilong Wang
Pages: 1799-1808
Published online on: 04 July 2018

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Article Open Access

Effects of FSS on the expression and localization of the core proteins in two Wnt signaling pathways, and their association with ciliogenesis

Xin Sheng, Yan Sheng, Yuehua Liu, Xiaoqiong Li, Bo Shu, Dayu Li
Pages: 1809-1818
Published online on: 05 July 2018

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Article Open Access

Targeted next‑generation sequencing identifies two novel COL2A1 gene mutations in Stickler syndrome with bilateral retinal detachment

Xinhua Huang, Ying Lin, Chuan Chen, Yi Zhu, Hongbin Gao, Tao Li, Bingqian Liu, Cancan Lyu, Ying Huang, Qingxiu Wu, Haichun Li, Chenjin Jin, Xiaoling Liang, Lin Lu
Pages: 1819-1826
Published online on: 04 July 2018

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Article Open Access

Shear stress promotes differentiation of stem cells from human exfoliated deciduous teeth into endothelial cells via the downstream pathway of VEGF-Notch signaling

Penglai Wang, Shaoyue Zhu, Changyong Yuan, Lei Wang, Jianguang Xu, Zongxiang Liu
Pages: 1827-1836
Published online on: 06 July 2018

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Article Open Access

A comprehensive analysis of prognosis prediction models based on pathway‑level, gene‑level and clinical information for glioblastoma

Ruqing Liang, Meng Wang, Guizhi Zheng, Hua Zhu, Yaqin Zhi, Zongwen Sun
Pages: 1837-1846
Published online on: 11 July 2018

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Article Open Access

Alantolactone induces apoptosis and suppresses migration in MCF‑7 human breast cancer cells via the p38 MAPK, NF‑κB and Nrf2 signaling pathways

Jianli Liu, Meijia Liu, Shuai Wang, Yin He, Yapeng Huo, Zhijun Yang, Xiangyu Cao
Pages: 1847-1856
Published online on: 04 July 2018

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Article Open Access

Ulipristal acetate induces cell cycle delay and remodeling of extracellular matrix

So‑Jin Shin, Jinyoung Kim, Seungmee Lee, Jongwoo Baek, Jin Eui Lee, Chiheum Cho, Eunyoung Ha
Pages: 1857-1864
Published online on: 17 July 2018

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Article Open Access

Screening of circular RNAs and validation of circANKRD36 associated with inflammation in patients with type 2 diabetes mellitus

Yuan Fang, Xiaoxia Wang, Wenqing Li, Jingli Han, Junhua Jin, Fei Su, Junhua Zhang, Wei Huang, Fei Xiao, Qi Pan, Lihui Zou
Pages: 1865-1874
Published online on: 18 July 2018

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Article Open Access

Piperlongumine decreases cognitive impairment and improves hippocampal function in aged mice

Jun Go, Tae‑Shin Park, Geun‑Hee Han, Hye‑Yeon Park, Young‑Kyoung Ryu, Yong‑Hoon Kim, Jung Hwan Hwang, Dong‑Hee Choi, Jung‑Ran Noh, Dae Youn Hwang, Sanghee Kim, Won Keun Oh, Chul‑Ho Lee, Kyoung‑Shim Kim
Pages: 1875-1884
Published online on: 18 July 2018

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Article Open Access

Oxidative stress in electrohypersensitivity self‑reporting patients: Results of a prospective in vivo investigation with comprehensive molecular analysis

Philippe Irigaray, Daniela Caccamo, Dominique Belpomme
Pages: 1885-1898
Published online on: 12 July 2018

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Article Open Access

Wogonin suppresses the LPS‑enhanced invasiveness of MDA‑MB‑231 breast cancer cells by inhibiting the 5‑LO/BLT2 cascade

Ji‑Hyun Go, Jun‑Dong Wei, Jae‑In Park, Kyung‑Seop Ahn, Jae‑Hong Kim
Pages: 1899-1908
Published online on: 12 July 2018

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Article Open Access

Ultrashortwave radiation promotes the recovery of spinal cord injury by inhibiting inflammation via suppression of the MK2/TNF‑α pathway

Nan Wang, Zhiping Feng, Wei Zhao, Zhiqiang Zhang, Lixin Zhang
Pages: 1909-1916
Published online on: 19 July 2018

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Article Open Access

Inhibition of autophagy via activation of PI3K/Akt/mTOR pathway contributes to the protection of hesperidin against myocardial ischemia/reperfusion injury

Xuefei Li, Xiaorong Hu, Jichun Wang, Weipan Xu, Chunfeng Yi, Ruisong Ma, Hong Jiang
Pages: 1917-1924
Published online on: 30 July 2018

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Article Open Access

Aloin suppresses lipopolysaccharide‑induced inflammation by inhibiting JAK1‑STAT1/3 activation and ROS production in RAW264.7 cells

Yunfei Ma, Tuo Tang, Lili Sheng, Ziqian Wang, Hong Tao, Qing Zhang, Yao Zhang, Zhilin Qi
Pages: 1925-1934
Published online on: 31 July 2018

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Article Open Access

Overexpression of Slit2 improves function of the paravascular pathway in the aging mouse brain

Ge Li, Xiaofei He, Hang Li, Yu'e Wu, Yalun Guan, Shuhua Liu, Huanhuan Jia, Yunfeng Li, Lijing Wang, Ren Huang, Zhong Pei, Yue Lan, Yu Zhang
Pages: 1935-1944
Published online on: 02 August 2018

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Article Open Access

Cyclooxygenase‑2‑mediated upregulation of heme oxygenase 1 mitigates the toxicity of deuterium‑tritium fusion radiation

Xiaoyao Yang, Hui Liu, Xu Jiang, Chufeng Jin, Zhao Xu, Taosheng Li, Zhigang Wang, Jun Wang
Pages: 1945-1954
Published online on: 01 August 2018

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Article Open Access

Pro‑atherogenic activation of A7r5 cells induced by the oxLDL/β2GPI/anti‑β2GPI complex

Ting Wang, Hang Ouyang, Hong Zhou, Longfei Xia, Xiaoyan Wang
Pages: 1955-1966
Published online on: 02 August 2018

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Article Open Access

Aspirin promotes osteogenic differentiation of human dental pulp stem cells

Mengtong Yuan, Yuanbo Zhan, Weiping Hu, Ying Li, Xiaohua Xie, Nan Miao, Han Jin, Bin Zhang
Pages: 1967-1976
Published online on: 02 August 2018

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Article Open Access

Reversibly immortalized hepatic progenitor cell line containing double suicide genes

Shu‑Yu Fang, Chao‑Qun Hu, Meng‑Nan Liu, Li Tao, Yi Wang, Meng‑Jia Gong, Yun He, Tong‑Chuan He, Yang Bi
Pages: 1977-1986
Published online on: 02 August 2018

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Article Open Access

A proteomic analysis of chemoresistance development via sequential treatment with doxorubicin reveals novel players in MCF‑7 breast cancer cells

Ann‑Katrin Sommer, Adam Hermawan, Bojan Ljepoja, Thomas Fröhlich, Georg J. Arnold, Ernst Wagner, Andreas Roidl
Pages: 1987-1997
Published online on: 18 July 2018

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Article Open Access

BMS‑345541 inhibits airway inflammation and epithelial‑mesenchymal transition in airway remodeling of asthmatic mice

Xiaohua Zhu, Qiugen Li, Guozhu Hu, Jun Wang, Qinghua Hu, Zhiqiang Liu, Gang Wu, Ying Zhong
Pages: 1998-2008
Published online on: 06 July 2018

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Article Open Access

Effect of autophagy on allodynia, hyperalgesia and astrocyte activation in a rat model of neuropathic pain

Hongguang Chen, Yajiao Hu, Keliang Xie, Yajun Chen, Huixing Wang, Yingxue Bian, Yanyan Wang, Aili Dong, Yonghao Yu
Pages: 2009-2019
Published online on: 06 July 2018

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Article Open Access

Magnesium isoglycyrrhizinate has hepatoprotective effects in an oxaliplatin‑induced model of liver injury

Xueqing Zou, Yongmei Wang, Cheng Peng, Ben Wang, Zhengchuan Niu, Zequn Li, Jun Niu
Pages: 2020-2030
Published online on: 19 July 2018

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Article Open Access

Titanium particle‑mediated osteoclastogenesis may be attenuated via bidirectional ephrin‑B2/eph‑B4 signaling in vitro

Yu‑Wei Ge, Zhi‑Qing Liu, Zhen‑Yu Sun, De‑Gang Yu, Kai Feng, Zhen‑An Zhu, Yuan‑Qing Mao
Pages: 2031-2041
Published online on: 17 July 2018

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Article Open Access

miR‑330‑5p inhibits H2O2‑induced adipogenic differentiation of MSCs by regulating RXRγ

Weiping Huang, Ke Li, Aijun Liu, Zeyu Yang, Chenxia Hu, Dongfeng Chen, Hongqi Wang
Pages: 2042-2052
Published online on: 12 July 2018

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Article Open Access

Effect of celastrol on toll‑like receptor 4‑mediated inflammatory response in free fatty acid‑induced HepG2 cells

Li‑Ping Han, Bei Sun, Chun‑Jun Li, Yun Xie, Li‑Ming Chen
Pages: 2053-2061
Published online on: 12 July 2018

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Article Open Access

Construction of a microRNA‑associated feed‑forward loop network that identifies regulators of cardiac hypertrophy and acute myocardial infarction

Wenbo Qu, Shuai Shi, Lixiu Sun, Fan Zhang, Shengming Zhang, Shuainan Mu, Yanru Zhao, Bingchen Liu, Xue Cao
Pages: 2062-2070
Published online on: 20 July 2018

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Article Open Access

Vγ9Vδ2 T cells inhibit immature dendritic cell transdifferentiation into osteoclasts through downregulation of RANK, c‑Fos and ATP6V0D2

Xiaolin Zhu, Zhiyong Zeng, Dongbiao Qiu, Junmin Chen
Pages: 2071-2079
Published online on: 23 July 2018

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Article Open Access

MicroRNAs as biomarkers for the progression and prognosis of colon carcinoma

Hui Zhang, Zhuo Wang, Rong Ma, Jianzhong Wu, Jifeng Feng
Pages: 2080-2088
Published online on: 25 July 2018

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Article Open Access

Inducible HSP70 antagonizes cisplatin‑induced cell apoptosis through inhibition of the MAPK signaling pathway in HGC‑27 cells

Lili Sheng, Tuo Tang, Yinhua Liu, Yunfei Ma, Ziqian Wang, Hong Tao, Yao Zhang, Zhilin Qi
Pages: 2089-2097
Published online on: 19 July 2018

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Article Open Access

Inhibition of proprotein convertase subtilisin/kexin type 9 attenuates neuronal apoptosis following focal cerebral ischemia via apolipoprotein E receptor 2 downregulation in hyperlipidemic mice

Lei Wang, Zi Wang, Jiandang Shi, Qian Jiang, Hong Wang, Xu Li, Di Hao
Pages: 2098-2106
Published online on: 31 July 2018

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Article Open Access

High-fluence low-power laser irradiation promotes odontogenesis and inflammation resolution in periodontitis by enhancing stem cell proliferation and differentiation

Tiejun Hou, Shanyong Li, Guangwei Zhang, Yan Li
Pages: 2107-2119
Published online on: 02 August 2018

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Article

Evaluation of intestinal injury, inflammatory response and oxidative stress following intracerebral hemorrhage in mice

Yijun Cheng, Jieyu Zan, Yaying Song, Guoyuan Yang, Hanbing Shang, Weiguo Zhao
Pages: 2120-2128
Published online on: 04 July 2018

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Article

Effects of a small, volatile bacterial molecule on Pseudomonas aeruginosa bacteria using whole cell high-resolution magic angle spinning nuclear magnetic resonance spectroscopy and genomics

Valeria Righi, Caterina Constantinou, Meenu Kesarwani, Laurence G. Rahme, A. Aria Tzika
Pages: 2129-2136
Published online on: 06 July 2018

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Article

Downregulation of hepatic lipase is associated with decreased CD133 expression and clone formation in HepG2 cells

Xuehua Liu, Junhua Zuo, Yuan Fang, Jing Wen, Feihong Deng, Hui Zhong, Bo Jiang, Jide Wang, Biao Nie
Pages: 2137-2144
Published online on: 04 July 2018

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Article

MicroRNA‑634 alters nerve apoptosis via the PI3K/Akt pathway in cerebral infarction

Yajun Chang, Wei Huang, Qian Sun, Suli Li, Zhongkai Yan, Qiumin Wang, Xiumin Liu
Pages: 2145-2154
Published online on: 13 July 2018

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Article

Formononetin protects against balloon injury‑induced neointima formation in rats by regulating proliferation and migration of vascular smooth muscle cells via the TGF‑β1/Smad3 signaling pathway

Tao Song, Jingdong Zhao, Tongbai Jiang, Xing Jin, Yubin Li, Xinrong Liu
Pages: 2155-2162
Published online on: 18 July 2018

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Article

miR‑199a‑3p/Sp1/LDHA axis controls aerobic glycolysis in testicular tumor cells

Shihua Zhou, Ziqian Min, Kang Sun, Sijie Qu, Jinrun Zhou, Hongyan Duan, Huawei Liu, Xiaowen Liu, Zhijun Gong, Dan Li
Pages: 2163-2174
Published online on: 12 July 2018

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Article

Role of lincRNA‑p21 in the protective effect of macrophage inhibition factor against hypoxia/serum deprivation‑induced apoptosis in mesenchymal stem cells

Wenzheng Xia, Lei Zhuang, Meng Hou
Pages: 2175-2184
Published online on: 12 July 2018

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Article

HSP90 limits thrombin‑stimulated IL‑6 synthesis in osteoblast‑like MC3T3‑E1 cells: Regulation of p38 MAPK

Kazuhiko Fujita, Takanobu Otsuka, Tetsu Kawabata, Shingo Kainuma, Go Sakai, Rie Matsushima‑Nishiwaki, Osamu Kozawa, Haruhiko Tokuda
Pages: 2185-2192
Published online on: 18 July 2018

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Article

Regenerative potential of human nucleus pulposus resident stem/progenitor cells declines with ageing and intervertebral disc degeneration

Hao Wu, Yupan Shang, Jiayue Yu, Xiaoli Zeng, Jinhua Lin, Mei Tu, Lek Hang Cheang, Jiaqing Zhang
Pages: 2193-2202
Published online on: 12 July 2018

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Article

Loss of conserved ubiquitylation sites in conserved proteins during human evolution

Dongbin Park, Chul Jun Goh, Hyein Kim, Ji Seok Lee, Yoonsoo Hahn
Pages: 2203-2212
Published online on: 12 July 2018

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Article

Effect of phlorotannins on myofibroblast differentiation and ECM protein expression in transforming growth factor β1‑induced nasal polyp‑derived fibroblasts

Jungik Park, Grace Choi, Mi‑Jin Yim, Jeong Min Lee, Jong Su Yoo, Won Sun Park, Seong Kook Park, Saegwang Park, Su‑Kil Seo, Tae‑Geum Kim, Dae‑Sung Lee, Il‑Whan Choi
Pages: 2213-2220
Published online on: 12 July 2018

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Article

Melatonin inhibits epithelial‑to‑mesenchymal transition in gastric cancer cells via attenuation of IL‑1β/NF‑κB/MMP2/MMP9 signaling

Xiaoting Wang, Bin Wang, Jieqiong Xie, Diyu Hou, Hui Zhang, Huifang Huang
Pages: 2221-2228
Published online on: 19 July 2018

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Article

Markers of activated inflammatory cells are associated with disease severity and intestinal microbiota in adults with non‑alcoholic fatty liver disease

Katherine J.P. Schwenger, Lina Chen, Adeline Chelliah, Hannah E. Da Silva, Anastasia Teterina, Elena M. Comelli, Amel Taibi, Bianca M. Arendt, Sandra Fischer, Johane P. Allard
Pages: 2229-2237
Published online on: 02 August 2018

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Article

Identification of genes and signaling pathways associated with arthrogryposis‑renal dysfunction‑cholestasis syndrome using weighted correlation network analysis

Miao Chai, Liju Su, Xiaolei Hao, Meng Zhang, Lihui Zheng, Jiabing Bi, Xiao Han, Bohai Yu
Pages: 2238-2246
Published online on: 12 July 2018

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Article

Long non‑coding RNA urothelial cancer associated 1 regulates radioresistance via the hexokinase 2/glycolytic pathway in cervical cancer

Li Fan, Chunxian Huang, Jing Li, Tian Gao, Zhongqiu Lin, Tingting Yao
Pages: 2247-2259
Published online on: 13 July 2018

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Article

Potential repositioning of GV1001 as a therapeutic agent for testosterone‑induced benign prostatic hyperplasia

Kyeong Seok Kim, Hun Yong Yang, Seung‑Cheol Chang, Young‑Mi Kim, Kwang Youl Lee, Byung Mu Lee, Hyung Sik Kim
Pages: 2260-2268
Published online on: 05 July 2018

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Article

Efficient increase of the novel recombinant human plasminogen activator expression level and stability through the use of homozygote transgenic rabbits

Zhengyi He, Lei Jiang, Ting Zhang, Minya Zhou, Daijin Wu, Tingting Yuan, Yuguo Yuan, Yong Cheng
Pages: 2269-2275
Published online on: 04 July 2018

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Article

Notch signalling induces epithelial‑mesenchymal transition to promote metastasis in oral squamous cell carcinoma

Jianping Zhang, Genjian Zheng, Lan Zhou, Pengcheng Li, Man Yun, Qi Shi, Tingli Wang, Xiaotong Wu
Pages: 2276-2284
Published online on: 12 July 2018

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Article

Scopoletin downregulates MMP‑1 expression in human fibroblasts via inhibition of p38 phosphorylation

Hae‑Lim Kim, Sung Min Woo, Woo Rin Choi, Hong‑Suk Kim, Chunsik Yi, Kyung‑Hyeon Kim, Jinhua Cheng, Seung Hwan Yang, Joo‑Won Suh
Pages: 2285-2293
Published online on: 04 July 2018

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Article

Effects of Ca2+/calmodulin‑dependent protein kinase pathway inhibitor KN93 on osteoclastogenesis

Yingxiao Fu, Dequn Niu, Wenfang Su, Qingling Yang, Wenrui Wang, Baoding Tang, Zhongwen Li, Ding Zhang, Yingji Mao, Chuang Li, Xue Li, Shihao Ye, Xu Su, Fanyuan Xu, Xuemin Sun, Changjie Chen
Pages: 2294-2302
Published online on: 25 July 2018

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Article

Gene expression profiles for predicting antibody‑mediated kidney allograft rejection: Analysis of GEO datasets

In‑Wha Kim, Jae Hyun Kim, Nayoung Han, Sangsoo Kim, Yon Su Kim, Jung Mi Oh
Pages: 2303-2311
Published online on: 31 July 2018

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Journal Cover
March-2026 Volume 57 Issue 3

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

Ginkgolide C alleviates atherosclerosis via activating Nrf2 to inhibit ROS‑dependent NLRP3 inflammasome activation

Rui Zhang
Article Number: 75
Published online on: 27 January 2026

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Review Open Access

MicroRNA‑microbiome cross‑kingdom networks drive inflammatory bowel disease through dynamic regulatory ecosystems (Review)

Liping Liang, Xiaoyan Liu, Bang Li, Huyi Lei, Zibo Tang, Shijie Mai, Chenghai Yang, Yongjian Zhou, Shaoheng Zhang, Le Liu
Article Number: 74
Published online on: 27 January 2026

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Review Open Access

Mechanistic insights into pancreatic cancer progression from circadian rhythm disruption and gut microbiota dysbiosis (Review)

Yang Liu, Yongfeng Li, Heng Ma, Shichang Deng, Chao Cheng
Article Number: 73
Published online on: 26 January 2026

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Retraction Open Access

[Retracted] miR‑124‑3p inhibits the viability and motility of glioblastoma multiforme by targeting RhoG  

Shan Cai, Chao-Jia Shi, Jian-Xiang Lu, Yan-Pei Wang, Tian Yuan, Xiang-Peng Wang
Article Number: 72
Published online on: 26 January 2026

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Natural products as multi‑target therapies for sepsis‑induced myocardial dysfunction (Review)

Fei Tang, Dong Liu, Shi-Chao Zhu, Hui-Min Zhou, Xue-Wen Qiu
Article Number: 71
Published online on: 22 January 2026

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MTHFR‑folate axis as a modulator of the epigenetic landscape in autoimmune diseases (Review)

Pablo Michael Navarro‑Rodríguez, Ramón Francisco Bajeca‑Serrano, Francisco Javier Turrubiates‑Hernández, Hazael Ramiro Ceja‑Gálvez, Jorge Hernández‑Bello, Cristian Oswaldo Hernández‑Ramírez, Saúl Ramírez‑de Los Santos, José Francisco Muñoz‑Valle
Article Number: 70
Published online on: 22 January 2026

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Article Open Access

Natural compound 5,7,8‑trimethoxyflavone mitigates radiation‑induced lung injury by suppressing EMT and PI3K/Akt pathway

Cui-Cui Gong, Hua-Kang Li, Yuan-Zhen Mi, Jun-Yang Chen, Zeng-Yi Fang, Shun-Lian Fu, Li Quan, Bing Lin, Jin-Yi Lang, Qiu Chen, Ke Xu, Mei-Hua Chen
Article Number: 69
Published online on: 21 January 2026

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Epigenetic dysregulation of B‑cells in autoimmune diseases and lymphomas (Review)

Yuxing Li, Yujiao Gong, Jiaxing Zhao, Rensen Ran
Article Number: 68
Published online on: 21 January 2026

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Research progress on the effects of macrophage‑derived exosomes on muscle factors IGF‑1 and FGF‑2 mediating musculoskeletal crosstalk molecular signaling pathway on bone metabolism (Review)

Ruo-Mei Cui, Mai Zheng, Jian-Bin Hong, Zheng-Xiang Wang, Yu-Fang Cun, Shu-Ji Gao, Yan-Lin Zhu, Zi-Bin Yang, Ming-Wei Liu
Article Number: 67
Published online on: 21 January 2026

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Expression of Concern Open Access

[Expression of Concern] Long non‑coding RNA SNHG20 promotes bladder cancer via activating the Wnt/β‑catenin signalling pathway

Qingsong Zhao, Saiyue Gao, Qingyan Du, Ye Liu
Article Number: 66
Published online on: 21 January 2026

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Mangiferin in human disease: Multifaceted mechanisms and applications (Review)

Yaling Dai, Qiuling Huang, Mengquan Tan, Zhifu Wang, Cai Jiang, Zheng Liu, Shenghang Zhang, Siyuan Song
Article Number: 65
Published online on: 21 January 2026

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Article

Deciphering the CAF‑LCN2 axis: Key to overcoming anti‑PD‑L1 immunotherapy resistance in lung cancer

Dan Xiao, Jing Yang, Jianying Zhou, Zhenzhen Hu, Ting Zhang
Article Number: 64
Published online on: 19 January 2026

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Retraction Open Access

[Retracted] DDAH2 alleviates myocardial fibrosis in diabetic cardiomyopathy through activation of the DDAH/ADMA/NOS/NO pathway in rats

Zhen-Dong Zhu, Ji-Ming Ye, Xue-Mei Fu, Xue-Chang Wang, Ji-Yun Ye, Xin-Ran Wu, Peng Hua, Yu-Qiong Liao, Wei Xuan, Jin-Lan Duan, Wei-Yuan Li, Hui Fu, Zhong-Hua Xia, Xuan Zhang
Article Number: 63
Published online on: 19 January 2026

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Beyond hepatic stellate cell heterogeneity: Resolving fibrosis, restoring regeneration (Review)

Chang Gao, Guiqing Chen, Hongyan Jia, Hong Zhu, Yun Cai, Dakai Yang, Kai Zhao
Article Number: 62
Published online on: 14 January 2026

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Correction Open Access

[Corrigendum] CDKN2A (p16INK4A) affects the anti‑tumor effect of CDK inhibitor in somatotroph adenomas

Yiyuan Chen, Zhenye Li, Qiuyue Fang, Hongyun Wang, Chuzhong Li, Hua Gao, Yazhuo Zhang
Article Number: 61
Published online on: 14 January 2026

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Review Open Access

Harnessing MSC‑derived exosomes to modulate the pathophysiology of ASD: Recent advances and therapeutic implications (Review)

Zhaojian Sun, Nouman Amjad, Majid Muhammad, Zhiyuan Li
Article Number: 60
Published online on: 13 January 2026

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Retraction Open Access

[Retracted] Mechanism of cell death induced by silica nanoparticles in hepatocyte cells is by apoptosis

Ye Yang, Xinjing Du, Qiang Wang, Jianwei Liu, Enguo Zhang, Linlin Sai, Cheng Peng, Martin F. Lavin, Abrey Jie Yeo, Xu Yang, Hua Shao, Zhongjun Du
Article Number: 59
Published online on: 12 January 2026

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ZG16B: A key regulator of tumor progression and immune microenvironment modulation in cancer (Review)

Xing-Ming Chen, Yu-Bo Liang, Jin-Xiang Zuo, Zi-Sheng Yang, Le-Yu Zhang, Xin-Yu Zhang, Ping Wan, Yang Ke
Article Number: 58
Published online on: 09 January 2026

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Retraction Open Access

[Retracted] Silica nanoparticles induce cardiomyocyte apoptosis via the mitochondrial pathway in rats following intratracheal instillation

Zhongjun Du, Shangya Chen, Guanqun Cui, Ye Yang, Enguo Zhang, Qiang Wang, Martin F. Lavin, Abrey J. Yeo, Cunxiang Bo, Yu Zhang, Chao Li, Xiaoshan Liu, Xu Yang, Cheng Peng, Hua Shao
Article Number: 57
Published online on: 05 January 2026

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Role of cuproptosis in digestive system tumors (Review)

Li Zhang, Yongpeng Cheng, Lulu Tang, Jiaxing Zhu, Biguang Tuo
Article Number: 56
Published online on: 02 January 2026

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Environmental exposure to air pollution and climate: Intersecting the impact on ear and nose health and chemosensory function (Review)

Yu-Chen Zhang, Lei Zhang, Ping-Ting Zhou, Zi-Hui Xie, Wen-Jie Zhang, Min Fan, Yan-Xun Han, Ye-Hai Liu, Yu-Chen Liu
Article Number: 55
Published online on: 31 December 2025

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Role and mechanisms of ferroptosis in cognitive impairment: From molecular pathways to therapeutic targets (Review)

Shenghui Ge, Deyue Kong, Shuyue Fan, Yi Luo, Xiao Yin, Zehua Jin, Wenqing Xia, Jianhua Ma
Article Number: 54
Published online on: 30 December 2025

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The GPR124‑Wnt‑PPARγ regulatory axis: Molecular mechanisms and therapeutic implications in chronic inflammatory diseases (Review)

Ming-Wang Cui, Si-Yu Tao, Tao Wen, Zhu-Ling Guo
Article Number: 53
Published online on: 30 December 2025

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Advances in RPGR gene therapy for X‑linked retinitis pigmentosa: From preclinical insights to clinical application (Review)

Yushan Long, Jia Qi, Wenliang Zhang, Huan Qin, Kai Yao
Article Number: 52
Published online on: 30 December 2025

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April-2026 Volume 57 Issue 4

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Role of vascular smooth muscle cell pathobiology in sepsis‑induced vasoplegia (Review)

Hang Ruan, Xiao-Yan Shen, Shi-Yan Liu, Shu-Sheng Li
Article Number: 87
Published online on: 06 February 2026

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Signalling pathways regulated by FSTL1 in inflammation and potential therapeutic applications (Review)

Changliang Ma, Jingxin Li, Wenting Jiang, Xiaoqiang Chen, Jianquan Liu, Xu Tao, Wencui Li, Zhiqin Deng, Zhe Zhao
Article Number: 86
Published online on: 05 February 2026

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Hypothermic machine perfusion protects DCD graft liver from ischemia‑reperfusion injury by enhancing macrophage efferocytosis via KLF2‑NLRP3 signaling

Qin Deng, Zhongzhong Liu, Qifa Ye, Jia Liu, Zhihui Fu, Xingjian Zhang, Jun Luo, Zhongshan Lu, Pengpeng Yue, Jiansheng Xiao, Qi Xiao
Article Number: 85
Published online on: 05 February 2026

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Mechanistic advances in exercise‑mediated regulation of autophagy dysfunction in Alzheimer's disease (Review)

Wei Li, Wen-Hong Wang, Yi Song, Xu-Jiong Li, Yan Li, Xia Wang, Ting-Ting Tian, Xiao Huang, Li Zhao
Article Number: 84
Published online on: 04 February 2026

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[Corrigendum] p57KIP2‑mediated inhibition of human trophoblast apoptosis and promotion of invasion in vitro

Guo-Qian He, Guang-Yu Liu, Wen-Ming Xu, Hui-Juan Liao, Xing-Hui Liu, Guo-Lin He
Article Number: 83
Published online on: 04 February 2026

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Lipid droplets beyond storage: Cellular metabolic modulator in the diabetic heart (Review)

Yongchun Liang, Xinbiao Fan, Xiaofei Geng, Yunfeng Jia, Wenyu Shang, Xitong Sun, Jun Ge, Guijun Ye, Boyu Zhu, Zheng Zhang, Yuxin Kang, Xiaoyu Shan, Junping Zhang
Article Number: 82
Published online on: 03 February 2026

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IMP metabolic mechanisms and IMPDH targeting strategies in tumor metabolic reprogramming and therapy (Review)

Hao Zhu, Hao Wang, Xia Li, Weisong Zhang, Yihao Wang, Qingze Tan, Dongxu Ying, Zhan Shi, Jianxiang Song
Article Number: 81
Published online on: 03 February 2026

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Ebastine targets HER2/HER3 signaling and cancer stem cell traits to overcome trastuzumab resistance in HER2‑positive breast cancer

Eunsun Jung, Ji Young Kim, Dongmi Ko, Juyeon Seo, Sang Yoon Lee, Daeun Lee, Subeen Kim, Minsu Park, Seongjae Kim, Soeun Park, Kyoungmin Lee, Yong Koo Kang, Kee Dal Nam, Yoon-Jae Kim, Jae Hong Seo
Article Number: 80
Published online on: 02 February 2026

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[Corrigendum] Inhibition of acid‑sensing ion channel 1a attenuates acid‑induced activation of autophagy via a calcium signaling pathway in articular chondrocytes

Wen-Fan Gao, Ya-Yun Xu, Jin-Fang Ge, Fei-Hu Chen
Article Number: 79
Published online on: 02 February 2026

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Immunological mechanisms and novel therapeutic strategies for sepsis‑associated acute kidney injury (Review)

Lu Xu, Wei Jiang, Lin Song, Jing Wang, Jiangquan Yu, Ruiqiang Zheng
Article Number: 78
Published online on: 30 January 2026

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Correction Open Access

[Corrigendum] Role of Smad3 signaling in the epithelial‑mesenchymal transition of the lens epithelium following injury

Fanlan Meng, Jun Li, Xiao Yang, Xiaoyong Yuan, Xin Tang
Article Number: 77
Published online on: 29 January 2026

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Spatial metabolomics: A new tool for unravelling the metabolic disorders and heterogeneity in diabetic kidney disease (Review)

Hanfei Li, Yuxi Li, Bo Zhang, Wenhao Cheng, Guowei Ma, Jin Rong, Shiru Duan, Di Feng, Tingting Zhao
Article Number: 76
Published online on: 29 January 2026

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