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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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International Journal of Molecular Medicine

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
October-2018 Volume 42 Issue 4

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Journal Metrics

Impact Factor: 8.5

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Functions of EpCAM in physiological processes and diseases (Review)

Li Huang, Yanhong Yang, Fei Yang, Shaomin Liu, Ziqin Zhu, Zili Lei, Jiao Guo
Pages: 1771-1785
Published online on: 11 July 2018

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Review

Circular RNA, a novel marker for cancer determination (Review)

Yinjie Su, Guangzheng Zhong, Ning Jiang, Ming Huang, Tianxin Lin
Pages: 1786-1798
Published online on: 30 July 2018

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Article Open Access

TGM2 knockdown reverses cisplatin chemoresistance in osteosarcoma

Cuiyun Li, Jing Cai, Fugui Ge, Guilong Wang
Pages: 1799-1808
Published online on: 04 July 2018

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Article Open Access

Effects of FSS on the expression and localization of the core proteins in two Wnt signaling pathways, and their association with ciliogenesis

Xin Sheng, Yan Sheng, Yuehua Liu, Xiaoqiong Li, Bo Shu, Dayu Li
Pages: 1809-1818
Published online on: 05 July 2018

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Article Open Access

Targeted next‑generation sequencing identifies two novel COL2A1 gene mutations in Stickler syndrome with bilateral retinal detachment

Xinhua Huang, Ying Lin, Chuan Chen, Yi Zhu, Hongbin Gao, Tao Li, Bingqian Liu, Cancan Lyu, Ying Huang, Qingxiu Wu, Haichun Li, Chenjin Jin, Xiaoling Liang, Lin Lu
Pages: 1819-1826
Published online on: 04 July 2018

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Article Open Access

Shear stress promotes differentiation of stem cells from human exfoliated deciduous teeth into endothelial cells via the downstream pathway of VEGF-Notch signaling

Penglai Wang, Shaoyue Zhu, Changyong Yuan, Lei Wang, Jianguang Xu, Zongxiang Liu
Pages: 1827-1836
Published online on: 06 July 2018

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Article Open Access

A comprehensive analysis of prognosis prediction models based on pathway‑level, gene‑level and clinical information for glioblastoma

Ruqing Liang, Meng Wang, Guizhi Zheng, Hua Zhu, Yaqin Zhi, Zongwen Sun
Pages: 1837-1846
Published online on: 11 July 2018

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Article Open Access

Alantolactone induces apoptosis and suppresses migration in MCF‑7 human breast cancer cells via the p38 MAPK, NF‑κB and Nrf2 signaling pathways

Jianli Liu, Meijia Liu, Shuai Wang, Yin He, Yapeng Huo, Zhijun Yang, Xiangyu Cao
Pages: 1847-1856
Published online on: 04 July 2018

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Article Open Access

Ulipristal acetate induces cell cycle delay and remodeling of extracellular matrix

So‑Jin Shin, Jinyoung Kim, Seungmee Lee, Jongwoo Baek, Jin Eui Lee, Chiheum Cho, Eunyoung Ha
Pages: 1857-1864
Published online on: 17 July 2018

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Article Open Access

Screening of circular RNAs and validation of circANKRD36 associated with inflammation in patients with type 2 diabetes mellitus

Yuan Fang, Xiaoxia Wang, Wenqing Li, Jingli Han, Junhua Jin, Fei Su, Junhua Zhang, Wei Huang, Fei Xiao, Qi Pan, Lihui Zou
Pages: 1865-1874
Published online on: 18 July 2018

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Article Open Access

Piperlongumine decreases cognitive impairment and improves hippocampal function in aged mice

Jun Go, Tae‑Shin Park, Geun‑Hee Han, Hye‑Yeon Park, Young‑Kyoung Ryu, Yong‑Hoon Kim, Jung Hwan Hwang, Dong‑Hee Choi, Jung‑Ran Noh, Dae Youn Hwang, Sanghee Kim, Won Keun Oh, Chul‑Ho Lee, Kyoung‑Shim Kim
Pages: 1875-1884
Published online on: 18 July 2018

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Article Open Access

Oxidative stress in electrohypersensitivity self‑reporting patients: Results of a prospective in vivo investigation with comprehensive molecular analysis

Philippe Irigaray, Daniela Caccamo, Dominique Belpomme
Pages: 1885-1898
Published online on: 12 July 2018

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Article Open Access

Wogonin suppresses the LPS‑enhanced invasiveness of MDA‑MB‑231 breast cancer cells by inhibiting the 5‑LO/BLT2 cascade

Ji‑Hyun Go, Jun‑Dong Wei, Jae‑In Park, Kyung‑Seop Ahn, Jae‑Hong Kim
Pages: 1899-1908
Published online on: 12 July 2018

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Article Open Access

Ultrashortwave radiation promotes the recovery of spinal cord injury by inhibiting inflammation via suppression of the MK2/TNF‑α pathway

Nan Wang, Zhiping Feng, Wei Zhao, Zhiqiang Zhang, Lixin Zhang
Pages: 1909-1916
Published online on: 19 July 2018

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Article Open Access

Inhibition of autophagy via activation of PI3K/Akt/mTOR pathway contributes to the protection of hesperidin against myocardial ischemia/reperfusion injury

Xuefei Li, Xiaorong Hu, Jichun Wang, Weipan Xu, Chunfeng Yi, Ruisong Ma, Hong Jiang
Pages: 1917-1924
Published online on: 30 July 2018

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Article Open Access

Aloin suppresses lipopolysaccharide‑induced inflammation by inhibiting JAK1‑STAT1/3 activation and ROS production in RAW264.7 cells

Yunfei Ma, Tuo Tang, Lili Sheng, Ziqian Wang, Hong Tao, Qing Zhang, Yao Zhang, Zhilin Qi
Pages: 1925-1934
Published online on: 31 July 2018

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Article Open Access

Overexpression of Slit2 improves function of the paravascular pathway in the aging mouse brain

Ge Li, Xiaofei He, Hang Li, Yu'e Wu, Yalun Guan, Shuhua Liu, Huanhuan Jia, Yunfeng Li, Lijing Wang, Ren Huang, Zhong Pei, Yue Lan, Yu Zhang
Pages: 1935-1944
Published online on: 02 August 2018

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Article Open Access

Cyclooxygenase‑2‑mediated upregulation of heme oxygenase 1 mitigates the toxicity of deuterium‑tritium fusion radiation

Xiaoyao Yang, Hui Liu, Xu Jiang, Chufeng Jin, Zhao Xu, Taosheng Li, Zhigang Wang, Jun Wang
Pages: 1945-1954
Published online on: 01 August 2018

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Article Open Access

Pro‑atherogenic activation of A7r5 cells induced by the oxLDL/β2GPI/anti‑β2GPI complex

Ting Wang, Hang Ouyang, Hong Zhou, Longfei Xia, Xiaoyan Wang
Pages: 1955-1966
Published online on: 02 August 2018

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Article Open Access

Aspirin promotes osteogenic differentiation of human dental pulp stem cells

Mengtong Yuan, Yuanbo Zhan, Weiping Hu, Ying Li, Xiaohua Xie, Nan Miao, Han Jin, Bin Zhang
Pages: 1967-1976
Published online on: 02 August 2018

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Article Open Access

Reversibly immortalized hepatic progenitor cell line containing double suicide genes

Shu‑Yu Fang, Chao‑Qun Hu, Meng‑Nan Liu, Li Tao, Yi Wang, Meng‑Jia Gong, Yun He, Tong‑Chuan He, Yang Bi
Pages: 1977-1986
Published online on: 02 August 2018

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Article Open Access

A proteomic analysis of chemoresistance development via sequential treatment with doxorubicin reveals novel players in MCF‑7 breast cancer cells

Ann‑Katrin Sommer, Adam Hermawan, Bojan Ljepoja, Thomas Fröhlich, Georg J. Arnold, Ernst Wagner, Andreas Roidl
Pages: 1987-1997
Published online on: 18 July 2018

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Article Open Access

BMS‑345541 inhibits airway inflammation and epithelial‑mesenchymal transition in airway remodeling of asthmatic mice

Xiaohua Zhu, Qiugen Li, Guozhu Hu, Jun Wang, Qinghua Hu, Zhiqiang Liu, Gang Wu, Ying Zhong
Pages: 1998-2008
Published online on: 06 July 2018

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Article Open Access

Effect of autophagy on allodynia, hyperalgesia and astrocyte activation in a rat model of neuropathic pain

Hongguang Chen, Yajiao Hu, Keliang Xie, Yajun Chen, Huixing Wang, Yingxue Bian, Yanyan Wang, Aili Dong, Yonghao Yu
Pages: 2009-2019
Published online on: 06 July 2018

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Article Open Access

Magnesium isoglycyrrhizinate has hepatoprotective effects in an oxaliplatin‑induced model of liver injury

Xueqing Zou, Yongmei Wang, Cheng Peng, Ben Wang, Zhengchuan Niu, Zequn Li, Jun Niu
Pages: 2020-2030
Published online on: 19 July 2018

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Article Open Access

Titanium particle‑mediated osteoclastogenesis may be attenuated via bidirectional ephrin‑B2/eph‑B4 signaling in vitro

Yu‑Wei Ge, Zhi‑Qing Liu, Zhen‑Yu Sun, De‑Gang Yu, Kai Feng, Zhen‑An Zhu, Yuan‑Qing Mao
Pages: 2031-2041
Published online on: 17 July 2018

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Article Open Access

miR‑330‑5p inhibits H2O2‑induced adipogenic differentiation of MSCs by regulating RXRγ

Weiping Huang, Ke Li, Aijun Liu, Zeyu Yang, Chenxia Hu, Dongfeng Chen, Hongqi Wang
Pages: 2042-2052
Published online on: 12 July 2018

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Article Open Access

Effect of celastrol on toll‑like receptor 4‑mediated inflammatory response in free fatty acid‑induced HepG2 cells

Li‑Ping Han, Bei Sun, Chun‑Jun Li, Yun Xie, Li‑Ming Chen
Pages: 2053-2061
Published online on: 12 July 2018

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Article Open Access

Construction of a microRNA‑associated feed‑forward loop network that identifies regulators of cardiac hypertrophy and acute myocardial infarction

Wenbo Qu, Shuai Shi, Lixiu Sun, Fan Zhang, Shengming Zhang, Shuainan Mu, Yanru Zhao, Bingchen Liu, Xue Cao
Pages: 2062-2070
Published online on: 20 July 2018

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Article Open Access

Vγ9Vδ2 T cells inhibit immature dendritic cell transdifferentiation into osteoclasts through downregulation of RANK, c‑Fos and ATP6V0D2

Xiaolin Zhu, Zhiyong Zeng, Dongbiao Qiu, Junmin Chen
Pages: 2071-2079
Published online on: 23 July 2018

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Article Open Access

MicroRNAs as biomarkers for the progression and prognosis of colon carcinoma

Hui Zhang, Zhuo Wang, Rong Ma, Jianzhong Wu, Jifeng Feng
Pages: 2080-2088
Published online on: 25 July 2018

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Article Open Access

Inducible HSP70 antagonizes cisplatin‑induced cell apoptosis through inhibition of the MAPK signaling pathway in HGC‑27 cells

Lili Sheng, Tuo Tang, Yinhua Liu, Yunfei Ma, Ziqian Wang, Hong Tao, Yao Zhang, Zhilin Qi
Pages: 2089-2097
Published online on: 19 July 2018

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Article Open Access

Inhibition of proprotein convertase subtilisin/kexin type 9 attenuates neuronal apoptosis following focal cerebral ischemia via apolipoprotein E receptor 2 downregulation in hyperlipidemic mice

Lei Wang, Zi Wang, Jiandang Shi, Qian Jiang, Hong Wang, Xu Li, Di Hao
Pages: 2098-2106
Published online on: 31 July 2018

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Article Open Access

High-fluence low-power laser irradiation promotes odontogenesis and inflammation resolution in periodontitis by enhancing stem cell proliferation and differentiation

Tiejun Hou, Shanyong Li, Guangwei Zhang, Yan Li
Pages: 2107-2119
Published online on: 02 August 2018

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Article

Evaluation of intestinal injury, inflammatory response and oxidative stress following intracerebral hemorrhage in mice

Yijun Cheng, Jieyu Zan, Yaying Song, Guoyuan Yang, Hanbing Shang, Weiguo Zhao
Pages: 2120-2128
Published online on: 04 July 2018

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Article

Effects of a small, volatile bacterial molecule on Pseudomonas aeruginosa bacteria using whole cell high-resolution magic angle spinning nuclear magnetic resonance spectroscopy and genomics

Valeria Righi, Caterina Constantinou, Meenu Kesarwani, Laurence G. Rahme, A. Aria Tzika
Pages: 2129-2136
Published online on: 06 July 2018

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Article

Downregulation of hepatic lipase is associated with decreased CD133 expression and clone formation in HepG2 cells

Xuehua Liu, Junhua Zuo, Yuan Fang, Jing Wen, Feihong Deng, Hui Zhong, Bo Jiang, Jide Wang, Biao Nie
Pages: 2137-2144
Published online on: 04 July 2018

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Article

MicroRNA‑634 alters nerve apoptosis via the PI3K/Akt pathway in cerebral infarction

Yajun Chang, Wei Huang, Qian Sun, Suli Li, Zhongkai Yan, Qiumin Wang, Xiumin Liu
Pages: 2145-2154
Published online on: 13 July 2018

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Article

Formononetin protects against balloon injury‑induced neointima formation in rats by regulating proliferation and migration of vascular smooth muscle cells via the TGF‑β1/Smad3 signaling pathway

Tao Song, Jingdong Zhao, Tongbai Jiang, Xing Jin, Yubin Li, Xinrong Liu
Pages: 2155-2162
Published online on: 18 July 2018

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Article

miR‑199a‑3p/Sp1/LDHA axis controls aerobic glycolysis in testicular tumor cells

Shihua Zhou, Ziqian Min, Kang Sun, Sijie Qu, Jinrun Zhou, Hongyan Duan, Huawei Liu, Xiaowen Liu, Zhijun Gong, Dan Li
Pages: 2163-2174
Published online on: 12 July 2018

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Article

Role of lincRNA‑p21 in the protective effect of macrophage inhibition factor against hypoxia/serum deprivation‑induced apoptosis in mesenchymal stem cells

Wenzheng Xia, Lei Zhuang, Meng Hou
Pages: 2175-2184
Published online on: 12 July 2018

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Article

HSP90 limits thrombin‑stimulated IL‑6 synthesis in osteoblast‑like MC3T3‑E1 cells: Regulation of p38 MAPK

Kazuhiko Fujita, Takanobu Otsuka, Tetsu Kawabata, Shingo Kainuma, Go Sakai, Rie Matsushima‑Nishiwaki, Osamu Kozawa, Haruhiko Tokuda
Pages: 2185-2192
Published online on: 18 July 2018

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Article

Regenerative potential of human nucleus pulposus resident stem/progenitor cells declines with ageing and intervertebral disc degeneration

Hao Wu, Yupan Shang, Jiayue Yu, Xiaoli Zeng, Jinhua Lin, Mei Tu, Lek Hang Cheang, Jiaqing Zhang
Pages: 2193-2202
Published online on: 12 July 2018

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Article

Loss of conserved ubiquitylation sites in conserved proteins during human evolution

Dongbin Park, Chul Jun Goh, Hyein Kim, Ji Seok Lee, Yoonsoo Hahn
Pages: 2203-2212
Published online on: 12 July 2018

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Article

Effect of phlorotannins on myofibroblast differentiation and ECM protein expression in transforming growth factor β1‑induced nasal polyp‑derived fibroblasts

Jungik Park, Grace Choi, Mi‑Jin Yim, Jeong Min Lee, Jong Su Yoo, Won Sun Park, Seong Kook Park, Saegwang Park, Su‑Kil Seo, Tae‑Geum Kim, Dae‑Sung Lee, Il‑Whan Choi
Pages: 2213-2220
Published online on: 12 July 2018

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Article

Melatonin inhibits epithelial‑to‑mesenchymal transition in gastric cancer cells via attenuation of IL‑1β/NF‑κB/MMP2/MMP9 signaling

Xiaoting Wang, Bin Wang, Jieqiong Xie, Diyu Hou, Hui Zhang, Huifang Huang
Pages: 2221-2228
Published online on: 19 July 2018

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Article

Markers of activated inflammatory cells are associated with disease severity and intestinal microbiota in adults with non‑alcoholic fatty liver disease

Katherine J.P. Schwenger, Lina Chen, Adeline Chelliah, Hannah E. Da Silva, Anastasia Teterina, Elena M. Comelli, Amel Taibi, Bianca M. Arendt, Sandra Fischer, Johane P. Allard
Pages: 2229-2237
Published online on: 02 August 2018

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Article

Identification of genes and signaling pathways associated with arthrogryposis‑renal dysfunction‑cholestasis syndrome using weighted correlation network analysis

Miao Chai, Liju Su, Xiaolei Hao, Meng Zhang, Lihui Zheng, Jiabing Bi, Xiao Han, Bohai Yu
Pages: 2238-2246
Published online on: 12 July 2018

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Article

Long non‑coding RNA urothelial cancer associated 1 regulates radioresistance via the hexokinase 2/glycolytic pathway in cervical cancer

Li Fan, Chunxian Huang, Jing Li, Tian Gao, Zhongqiu Lin, Tingting Yao
Pages: 2247-2259
Published online on: 13 July 2018

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Article

Potential repositioning of GV1001 as a therapeutic agent for testosterone‑induced benign prostatic hyperplasia

Kyeong Seok Kim, Hun Yong Yang, Seung‑Cheol Chang, Young‑Mi Kim, Kwang Youl Lee, Byung Mu Lee, Hyung Sik Kim
Pages: 2260-2268
Published online on: 05 July 2018

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Article

Efficient increase of the novel recombinant human plasminogen activator expression level and stability through the use of homozygote transgenic rabbits

Zhengyi He, Lei Jiang, Ting Zhang, Minya Zhou, Daijin Wu, Tingting Yuan, Yuguo Yuan, Yong Cheng
Pages: 2269-2275
Published online on: 04 July 2018

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Article

Notch signalling induces epithelial‑mesenchymal transition to promote metastasis in oral squamous cell carcinoma

Jianping Zhang, Genjian Zheng, Lan Zhou, Pengcheng Li, Man Yun, Qi Shi, Tingli Wang, Xiaotong Wu
Pages: 2276-2284
Published online on: 12 July 2018

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Article

Scopoletin downregulates MMP‑1 expression in human fibroblasts via inhibition of p38 phosphorylation

Hae‑Lim Kim, Sung Min Woo, Woo Rin Choi, Hong‑Suk Kim, Chunsik Yi, Kyung‑Hyeon Kim, Jinhua Cheng, Seung Hwan Yang, Joo‑Won Suh
Pages: 2285-2293
Published online on: 04 July 2018

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Article

Effects of Ca2+/calmodulin‑dependent protein kinase pathway inhibitor KN93 on osteoclastogenesis

Yingxiao Fu, Dequn Niu, Wenfang Su, Qingling Yang, Wenrui Wang, Baoding Tang, Zhongwen Li, Ding Zhang, Yingji Mao, Chuang Li, Xue Li, Shihao Ye, Xu Su, Fanyuan Xu, Xuemin Sun, Changjie Chen
Pages: 2294-2302
Published online on: 25 July 2018

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Article

Gene expression profiles for predicting antibody‑mediated kidney allograft rejection: Analysis of GEO datasets

In‑Wha Kim, Jae Hyun Kim, Nayoung Han, Sangsoo Kim, Yon Su Kim, Jung Mi Oh
Pages: 2303-2311
Published online on: 31 July 2018

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Journal Cover
November-2026 Volume 58 Issue 5

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Journal Metrics

Impact Factor: 8.5

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

Spatial multi‑omics identifies an SPP1+ macrophage‑driven anti‑apoptotic niche in osteoarthritis synovium via the SPP1‑CD44 axis

Han Gong, Hao Shen, Feng Zhang, Wei Wang, Sheng Zhou, Lei Wang, Yu Sun
Article Number: 334
Published online on: 29 September 2026

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Review Open Access

Novel insights into the role of the renal interstitial microenvironment in Randall's plaque formation (Review)

Jialiang Wang, Zhangcheng Liao, Minghui Liu, Yizhou Wang, Yu Cui, Hequn Chen, Feng Zeng, Zewu Zhu
Article Number: 333
Published online on: 29 September 2026

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Correction Open Access

[Corrigendum] Alteration of the Wnt/GSK3β/β‑catenin signalling pathway by rapamycin ameliorates pathology in an Alzheimer's disease model

Jingfei Chen, Zhimin Long, Yanzhen Li, Min  Luo, Shifang  Luo, Guiqiong He
Article Number: 332
Published online on: 28 September 2026

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Article Open Access

miR‑222‑3p inhibits diabetic skin wound healing by targeting APLN

Ruyan Jie, Ying Tang, Tingting Wu, Chenfan Zhang, Man Song, Xiaotong Zhao, Mingwei Chen
Article Number: 331
Published online on: 25 September 2026

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Correction Open Access

[Corrigendum] Adjudin delays cellular senescence through Sirt3‑mediated attenuation of ROS production

Keyi Geng, Ningzhen Fu, Xiao Yang, Weiliang Xia
Article Number: 330
Published online on: 23 September 2026

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Article Open Access

Salidroside attenuates myocardial ischemia‑reperfusion‑induced oxidative stress and ferroptosis by promoting USP11‑mediated  deubiquitination of PRDX2

Zhi-Cong Qiu, Jian-Nan Li, Yi-Zhou Li, Zi-Ming Wu, Xu-Dong Luo, Rui-Yuan Zeng, Song-Qing Lai, Shi-Tao Zhao, Li Wan
Article Number: 329
Published online on: 23 September 2026

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Reprogramming of cell death in gastric cancer: From molecular mechanisms to therapeutic potential (Review)

Mengru Liu, Zhujun Wu, Qiao Chen, Weiguo Ni, Ying Chen, Yixin Zhu, Yu Chen, Haifeng Ma, Yan Lin
Article Number: 328
Published online on: 23 September 2026

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Remimazolam attenuates myocardial ischemia/reperfusion injury by inhibiting ferroptosis involving the AKT/SLC7A11/GPX4 axis

Xiyuan Chen, Jianghong Zhao, Xingtong He, Yuqi Zhang, Jiao Wu, Chao Jiang, Yi Yang, Ji Xiao
Article Number: 327
Published online on: 22 September 2026

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Tumor‑immune spatiotemporal co‑evolution: A new paradigm for understanding and overcoming therapy resistance in metastatic castration‑resistant prostate cancer (Review)

Li Yan, Xiaoke Sun, Pengxiao Su
Article Number: 326
Published online on: 21 September 2026

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Research progress on the role of IL‑37 in gynecological and obstetrics‑related diseases (Review)

Hongjing Wang, Renukha Arjune, Weiyu Gan, Na Guo, Nan Yu, Ting Xiong
Article Number: 325
Published online on: 21 September 2026

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Expression of Concern Open Access

[Expression of Concern] PAT protein mRNA expression in primary rat hepatocytes: Effects of exposure to fatty acids

Elena Grasselli, Adriana Voci, Carlo Pesce, Laura Canesi, Emilia Fugassa, Gabriella Gallo, Laura Vergani
Article Number: 324
Published online on: 21 September 2026

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Neutrophil extracellular traps in cardiovascular disease: Mechanisms and therapeutic implications (Review)

Zhao Wang, Mingde Chang, Wenyu Shang, Yunfeng Jia, Xiaoyu Shan, Xinnong Chen, Yingxi Yang, Junping Zhang
Article Number: 323
Published online on: 18 September 2026

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Sirt1 attenuates calcific aortic valve disease by inhibiting ferroptosis and enhancing mitochondrial function via the activation of the Nrf2/HO‑1/FTH1 axis

Fei Yan, Lei Shi, Yuechan Wang, Ying Zhao, Yuanyuan Wu, Dubiao Xian, Yunheng Liang, Ning Wang, Hongwang Cui, Minni Zhang
Article Number: 322
Published online on: 18 September 2026

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Ketogenic diet attenuates Müller cell activation and retinal neuroinflammation in autoimmune glaucoma through acetylation‑mediated FOXO signalling

Sisi Tan, Xiaochen Wang, Yunfan Zheng, Zhenni Mou, Lihong Zeng, Jingchang Yuan, Xiao Fan, Miao Wei, Yujia Huo, Ruotong Ouyang, Yanyu Pu, Junqin Lei, Xi Gao, Dangdang Wang, Yang Peng, Hong Li
Article Number: 321
Published online on: 17 September 2026

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ILC3s as central regulators of mucosal homeostasis and disease pathogenesis (Review)

Jingwen Zhang, Lili Bao, Jiaxi Li, Xia Li, Lu Qiao, Jiaxian Cui, Xiaoxia He, Mingyu Zhang, Jingkun Lu, Xuan Zhang, Jing Dong, Gesi Tao, Yaoqing Feng, Yun Peng Tian, Pengwei Zhao, Ya Tuo
Article Number: 320
Published online on: 17 September 2026

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Small extracellular vesicles in osteoarthritis: A double‑edged sword regulating inflammation and cartilage homeostasis (Review)

Yifan Yang, Jiachen Liang, Xiangyu Shi, Anqi Niu, Ruifang Gao, Xiuping Wu, Xiaojuan Guo, Xiaotong Shi, Kejie Cao, Bing Li, Ran Li
Article Number: 319
Published online on: 17 September 2026

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Exosomal circular RNAs in the tumor immune microenvironment: From regulatory mechanisms to therapeutic opportunities and translational hurdles (Review)

Wenlong Zhang, Nuo Chen, Liya Gong, Yu Dong, Hui Shen, Xin Liu, Jie Sun, Luxuan Liu, Zhe Jin, Liaoyuan Wang, Xue Han, Bin Zhang, Shuixing Zhang
Article Number: 318
Published online on: 17 September 2026

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Expression of Concern Open Access

[Expression of Concern] Ginsenoside Rg1 protects against H2O2‑induced neuronal damage due to inhibition of the NLRP1 inflammasome signalling pathway in hippocampal neurons in vitro

Tan-Zhen Xu, Xiao-Yan Shen, Ling-Ling Sun, Ya-Li Chen, Bi-Qiong Zhang, Da-Ke Huang, Wei-Zu Li
Article Number: 317
Published online on: 16 September 2026

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tRNA‑derived RNAs in hepatic diseases: From biological functions to clinical translation (Review)

Yaotian Cai, Yifei Chen, Fuji Yang, Yongmin Yan, Ting Jiang
Article Number: 316
Published online on: 15 September 2026

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Monocytes in pneumonia: Functional plasticity and innate memory (Review) 

Run-Ze Li, Zhi-Han Xie, Li Chen, Yun-Xiao Shang, Fei Wang, Wan-Jie Huang, Qi Cheng
Article Number: 315
Published online on: 15 September 2026

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Correction Open Access

[Corrigendum] Integrative transcriptomic analysis unveils FXR as a key regulator of intestinal stemness and inflammation in ulcerative colitis

Hao Lin, Xinran Cheng, Yangyang Ren, Yongmei Zhang, Weixu Chen, Qingyan Lu, Yiqing Tian
Article Number: 314
Published online on: 14 September 2026

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Ferroptosis in heatstroke: Mechanisms and therapeutic perspectives (Review)

Hongguang Gao, Yang Chen, Tianshan Zhang, Yujun Shi, Rong Yao
Article Number: 313
Published online on: 10 September 2026

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Correction Open Access

[Corrigendum] Inactivation of von Hippel‑Lindau increases ovarian cancer cell aggressiveness through the HIF1α/miR‑210/VMP1 signaling pathway

Ting Liu, Le Zhao, Wei Chen, Zhen Li, Huilian Hou, Lu Ding, Xu Li
Article Number: 312
Published online on: 10 September 2026

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Interferon regulatory factors orchestrate CD8+ T cell function (Review)

Fa-Xi Wang, Chun-Liang Yang, Shan-Jie Rong, Qi-Jie Chen, Xiong-Tao Yue, Fei Sun
Article Number: 311
Published online on: 08 September 2026

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Expression of Concern Open Access

[Expression of Concern] Rapamycin‑induced miR‑30a downregulation inhibits senescence of VSMCs by targeting Beclin1

Pan Tan, Haiqin Wang, Junkun Zhan, Xinyu Ma, Xingjun Cui, Yanjiao Wang, Yi Wang, Jiayu Zhong, Youshuo Liu
Article Number: 310
Published online on: 07 September 2026

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Deciphering the function and mechanism of extracorporeal shock wave therapy in knee osteoarthritis (Review)

Yixuan Chen, Siqi Song, Yuchen Zhu, Shiqi Wang, Jieyuan Hu, Chenxu Liu, Yuchen Cai, Yushi Hu
Article Number: 309
Published online on: 04 September 2026

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Multi‑omics integration in osteoarthritis: Unraveling cell‑type‑specific gene‑metabolite networks for precision medicine (Review)

Ying Yang, Ruichen Zheng, Yun Zhang, Dongmei Ye, Jiale Xie, Changliang Zhu
Article Number: 308
Published online on: 03 September 2026

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Autophagy determines the fate of immune cells by regulating metabolic remodeling and PANoptosis (Review)

Yanan Guo, Xinyue Zhou, Yixiao Tian, Dan Chen, Xiaofeng Xie, Bin Zhou, Yingxia Tian, Yaqing Zhang
Article Number: 307
Published online on: 03 September 2026

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Programmed cell death in metabolic syndrome: From molecular mechanisms to therapeutic strategies (Review)

Jialin Zhong, Maofu Zhang, Yafang Zheng, Cuicui Gong, Yasheng Deng, Lisha Sun, Dongqi Zhou, Qian Zhou, Qiu Chen
Article Number: 306
Published online on: 03 September 2026

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Research progress on lysine acetylation (Review)

Minghui Zhang, Yuqi Zhang, Haoxin Yin, Junyuan Yan, Yingling Dong, Xin Zhao, Tianyi Cui, Bin Lv, Xiumei Gao
Article Number: 305
Published online on: 02 September 2026

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Expression of Concern Open Access

[Expression of Concern] Human ether‑à‑go‑go‑related gene mutation L539fs/47‑hERG leads to cell apoptosis through the endoplasmic reticulum stress pathway

Shuting Ma, Yun Zhao, Miaomiao Cao, Chaofeng Sun
Article Number: 304
Published online on: 02 September 2026

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Targeting integrated cell death networks in sepsis‑associated acute kidney injury: Shared regulatory nodes and diet‑related small molecule modulation (Review)

Lin Song, Aifeng He, Wei Jiang, Keran Shi, Jing Wang, Lu Xu, Jiangquan Yu, Ruiqiang Zheng
Article Number: 303
Published online on: 31 August 2026

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Article Open Access

Effect of MALT1 inhibition by MI‑2 on the microglial phenotype switch, inflammatory cytokine secretion, neuronal loss and oxidative stress in Alzheimer's disease

Yuanlong Li, Hua Fan, Xiong Han, Ming Ni, Xiaodan Hou, Hailan Xia, Yinzhu Shi, Lin Zhang, Jun Sun
Article Number: 302
Published online on: 31 August 2026

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Salvianolic acid monomers against metastasis: Decoding the multilayered interception of EMT, angiogenesis and immune evasion (Review)

Shiting Jiang, Dan Liu, Tingting Wei, Qiwei Shi, Haowen Wang, Yidan Gao, Pingsu Mao, Wenli Yang
Article Number: 301
Published online on: 31 August 2026

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Retraction Open Access

[Retracted] Silencing of decoy receptor 3 (DcR3) expression by siRNA in pancreatic carcinoma cells induces Fas ligand‑mediated apoptosis in vitro and in vivo

Jian Zhou, Shiduo Song, Songbin He, Zhenxin Wang, Bing Zhang, Dechun Li, Dongming Zhu
Article Number: 300
Published online on: 31 August 2026

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Research progress on BTG2 in non‑tumor diseases (Review)

Shuling Li, Xiaomei Liu, Zheng Zhang, Ling Yang, Yuxuan Li, Qiongdan Hu
Article Number: 299
Published online on: 28 August 2026

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Breaking the cycle of fibrosis: Ferroptosis as a therapeutic target (Review)

Xincheng Feng, Jue Zhang, Qinghong Ma, Chao Sun
Article Number: 298
Published online on: 27 August 2026

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Correction Open Access

[Corrigendum] Tumor‑targeting novel manganese complex induces ROS‑mediated apoptotic and autophagic cancer cell death

Jia Liu, Wenjie Guo, Jing Li, Xiang Li, Ji Geng, Qiuyun Chen, Jing Gao
Article Number: 297
Published online on: 26 August 2026

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Advances in sirtuin research in lung diseases (Review)

Shuangyun Xi, Weijun Chen, Xiuli Li, Yudan Wang, Yong Ke
Article Number: 296
Published online on: 25 August 2026

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Article Open Access

lncRNA TUG1 mediates palmitic acid‑induced neuronal lipotoxic injury via the miR‑449a‑5p/caspase‑3 and Akt/GSK‑3β axes

Ya-Dong Wei, Peng-Quan Chen, Xin Zheng, Le-Qi Wu, Xin-Yi Wang, Xin-Ran Gao, Jin-Fang Ge
Article Number: 295
Published online on: 25 August 2026

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Retraction Open Access

[Retracted] Downregulation of LINC00707 promotes osteogenic differentiation of human bone marrow‑derived mesenchymal stem cells by regulating DKK1 via targeting miR‑103a‑3p

Jun Liu, Minfei Wu, Guang Feng, Rui Li, Yang Wang, Jianhang Jiao
Article Number: 294
Published online on: 24 August 2026

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December-2026 Volume 58 Issue 6

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Journal Metrics

Impact Factor: 8.5

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Anesthetics and cancer biology: Translational evidence from perioperative modulation to drug repurposing (Review)

Ting Yang, Jiao Tang, Muhammad Saqib Mudabbar, Huan Hu, Qiang Fu, Chunlan Pu
Article Number: 336
Published online on: 05 October 2026

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Expression of Concern Open Access

[Expression of Concern] Multiple roles of SOCS proteins: Differential expression of SOCS1 and SOCS3 in atherosclerosis

Xiao Liang, Ming He, Tao Chen, Yan Liu, Yu-Ling Tian, Yu-Liang Wu, Yan Zhao, Yan Shen, Zu-Yi Yuan
Article Number: 335
Published online on: 30 September 2026

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