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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
January 2013 Volume 29 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

Dysregulation of signaling pathways and putative biomarkers in liver cancer stem cells (Review)

Kai Song, Junhua Wu, Chunping Jiang
Pages: 3-12
Published online on: 17 October 2012

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Article Open Access

Suppression of FUT1 attenuates cell proliferation in the HER2-overexpressing cancer cell line NCI-N87

Sadayuki Kawai, Shunsuke Kato, Hiroo Imai, Yoshinari Okada, Chikashi Ishioka
Pages: 13-20
Published online on: 01 November 2012

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Article Open Access

CD9 expression as a favorable prognostic marker for patients with malignant mesothelioma

Vishwa Jeet Amatya, Yukio Takeshima, Keisuke Aoe, Nobukazu Fujimoto, Toshihiro Okamoto, Taketo Yamada, Takumi Kishimoto, Chikao Morimoto, Kouki Inai
Pages: 21-28
Published online on: 31 October 2012

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Article Open Access

Antineoplastic activity of a nutrient mixture in Y-79 malignant retinoblastoma cells

M. Waheed Roomi, Nusrath Roomi, Bilwa Bhanap, Aleksandra Niedzwiecki, Matthias Rath
Pages: 29-33
Published online on: 29 October 2012

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Article Open Access

The nuclear factor-κB correlates with increased expression of interleukin-6 and promotes progression of gastric carcinoma

Yefeng Yin, Xiulian Si, Yan Gao, Lei Gao, Jiangning Wang
Pages: 34-38
Published online on: 19 October 2012

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Article Open Access

Influence of vascular endothelial growth factor single nucleotide polymorphisms on non-small cell lung cancer tumor angiogenesis

Ai Maeda, Masao Nakata, Koichiro Yasuda, Takuro Yukawa, Shinsuke Saisho, Riki Okita, Yuji Hirami, Katsuhiko Shimizu
Pages: 39-44
Published online on: 09 October 2012

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Article

Antiproliferative effect of the HSP90 inhibitor NVP-AUY922 is determined by the expression of PTEN in esophageal cancer

Xiao-Hong Bao, Munenori Takaoka, Hui-Fang Hao, Takuya Fukazawa, Tomoki Yamatsuji, Kazufumi Sakurama, Nagio Takigawa, Motowo Nakajima, Toshiyoshi Fujiwara, Yoshio Naomoto
Pages: 45-50
Published online on: 09 October 2012

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Article

Sequential effects of the proteasome inhibitor bortezomib and chemotherapeutic agents in uterine cervical cancer cell lines

Yuichiro Miyamoto, Shunsuke Nakagawa, Osamu Wada-Hiraike, Takayuki Seiki, Michihiro Tanikawa, Haruko Hiraike, Kenbun Sone, Kazunori Nagasaka, Katsutoshi Oda, Kei Kawana, Keiichi Nakagawa, Tomoyuki Fujii, Tetsu Yano, Shiro Kozuma, Yuji Taketani
Pages: 51-57
Published online on: 05 October 2012

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Article

Upregulation of phosphorylated cofilin 1 correlates with taxol resistance in human ovarian cancer in vitro and in vivo

Min Li, Jie Yin, Ning Mao, Lingya Pan
Pages: 58-66
Published online on: 12 October 2012

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Article

MiR-145 reduces ADAM17 expression and inhibits in vitro migration and invasion of glioma cells

Yong Lu, Michael Chopp, Xuguang Zheng, Mark Katakowski, Benjamin Buller, Feng Jiang
Pages: 67-72
Published online on: 17 October 2012

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Article

Netrin-4 overexpression suppresses primary and metastatic colorectal tumor progression

Clarisse Eveno, Jean-Olivier Contreres, Patricia Hainaud, Judith Nemeth, Evelyne Dupuy, Marc Pocard
Pages: 73-78
Published online on: 23 October 2012

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Article

Overexpression of oxidored-nitro domain containing protein 1 inhibits human nasopharyngeal carcinoma and cervical cancer cell proliferation and induces apoptosis: Involvement of mitochondrial apoptotic pathways

Jue Ouyang, Minghua Wu, Chen Huang, Li Cao, Guiyuan Li
Pages: 79-86
Published online on: 23 October 2012

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Article

Expression and clinical significance of HMGB1 in human liver cancer: Knockdown inhibits tumor growth and metastasis in vitro and in vivo

Ya-Dong Dong, Long Cui, Cheng-Hong Peng, Dong-Feng Cheng, Bao-San Han, Fang Huang
Pages: 87-94
Published online on: 04 October 2012

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Article

Human papillomavirus 16/18 E5 promotes cervical cancer cell proliferation, migration and invasion in vitro and accelerates tumor growth in vivo

Shujie Liao, Dongrui Deng, Weina Zhang, Xiaoji Hu, Wei Wang, Hui Wang, Yunping Lu, Shixuan Wang, Li Meng, Ding Ma
Pages: 95-102
Published online on: 26 October 2012

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Article

Casticin induces growth suppression and cell cycle arrest through activation of FOXO3a in hepatocellular carcinoma

Lihua He, Xiaohong Yang, Xiaocheng Cao, Fei Liu, Meifang Quan, Jianguo Cao
Pages: 103-108
Published online on: 09 October 2012

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Article

Nogo-B promotes the epithelial-mesenchymal transition in HeLa cervical cancer cells via Fibulin-5 Corrigendum in /10.3892/or.2022.8311

Wei Xiao, Shumin Zhou, Hua Xu, Heng Li, Guoqing He, Yingle Liu, Yipeng Qi
Pages: 109-116
Published online on: 04 October 2012

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Article

Curcumin inhibits LPS-induced EMT through downregulation of NF-κB-Snail signaling in breast cancer cells

Tao Huang, Zhijun Chen, Liping Fang
Pages: 117-124
Published online on: 16 October 2012

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Article

Identification of DNA methylation of SOX9 in cervical cancer using methylated-CpG island recovery assay

Jian-Hong Wu, Xue-Ai Liang, Yu-Mei Wu, Feng-Shuang Li, Yin-Mei Dai
Pages: 125-132
Published online on: 09 October 2012

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Article

Impact of GLUT1 and Ki-67 expression on early‑stage lung adenocarcinoma diagnosed according to a new international multidisciplinary classification

Yuho Maki, Junichi Soh, Kouichi Ichimura, Kazuhiko Shien, Masashi Furukawa, Takayuki Muraoka, Norimitsu Tanaka, Tsuyoshi Ueno, Hiromasa Yamamoto, Hiroaki Asano, Kazunori Tsukuda, Shinichi Toyooka, Shinichiro Miyoshi
Pages: 133-140
Published online on: 17 October 2012

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Article

Macrophages as independent prognostic factors in small T1 breast cancers

Roberto Carrio, Tulay Koru-Sengul, Feng Miao, Stefan Glück, Omar Lopez, Yamil Selman, Consuelo Alvarez, Clara Milikowski, Carmen Gomez, Merce Jorda, Mehrad Nadji, Marta Torroella-Kouri
Pages: 141-148
Published online on: 17 October 2012

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Article

INSL5 is a novel marker for human enteroendocrine cells of the large intestine and neuroendocrine tumours

Thatchawan Thanasupawat, Katrin Hammje, Ibrahim Adham, Jean-Eric Ghia, Marc R. Del Bigio, Jerry Krcek, Cuong Hoang-Vu, Thomas Klonisch, Sabine Hombach-Klonisch
Pages: 149-154
Published online on: 31 October 2012

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Article

OCT4 regulates epithelial-mesenchymal transition and its knockdown inhibits colorectal cancer cell migration and invasion

Xinzheng Dai, Jing Ge, Xuehao Wang, Xiaofeng Qian, Chuanyong Zhang, Xiangcheng Li
Pages: 155-160
Published online on: 17 October 2012

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Article

miR-27a regulates the self renewal of the H446 small cell lung cancer cell line in vitro

Yajing Miao, Jiayin Li, Xiaofei Qiu, Yanlei Li, Zhengyan Wang, Yajing Luan
Pages: 161-168
Published online on: 19 October 2012

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Article

Differential expression profiles of microRNAs as potential biomarkers for the early diagnosis of esophageal squamous cell carcinoma

Miao Yang, Ran Liu, Jingyi Sheng, Juan Liao, Yi Wang, Enchun Pan, Wei Guo, Yuepu Pu, Lihong Yin
Pages: 169-176
Published online on: 23 October 2012

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Article

Downregulation of LRIG1 expression by RNA interference promotes the aggressive properties of glioma cells via EGFR/Akt/c-Myc activation

Ruifan Xie, Hai Yang, Qungen Xiao, Feng Mao, Suojun Zhang, Fei Ye, Feng Wan, Baofeng Wang, Ting Lei, Dongsheng Guo
Pages: 177-184
Published online on: 23 October 2012

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Article

Abnormal expression of the mitotic checkpoint protein BubR1 contributes to the anti-microtubule drug resistance of esophageal squamous cell carcinoma cells

Min Hu, Qingsong Liu, Peipei Song, Xiaoqin Zhan, Min Luo, Chen Liu, Dandan Yang, Yan Cai, Fan Zhang, Fengbing Jiang, Yan Zhang, Min Tang, Guowei Zuo, Lan Zhou, Jinyong Luo, Qiong Shi, Yaguang Weng
Pages: 185-192
Published online on: 31 October 2012

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Article

Overexpression of the prolyl isomerase PIN1 promotes cell growth in osteosarcoma cells

Lu Zhou, Byung-Hyun Park, Jong Hyuk Park, Kyu Yun Jang, Ho Sung Park, Sajeev Wagle, Kwang-Bok Lee, Jung Ryul Kim
Pages: 193-198
Published online on: 30 October 2012

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Article

Live attenuated measles virus vaccine induces apoptosis and promotes tumor regression in lung cancer

Danhua Zhao, Ping Chen, Huiqiang Yang, Yonglin Wu, Xianwu Zeng, Yu Zhao, Yanjun Wen, Xia Zhao, Xiaolin Liu, Yuquan Wei, Yuhua Li
Pages: 199-204
Published online on: 29 October 2012

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Article

Value of 11C-choline PET/CT for lung cancer diagnosis and the relation between choline metabolism and proliferation of cancer cells

Meng Li, Zhongmin Peng, Qingwei Liu, Jian Sun, Shuzhan Yao, Qi Liu
Pages: 205-211
Published online on: 23 October 2012

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Article

Jolkinolide B induces apoptosis in MCF-7 cells through inhibition of the PI3K/Akt/mTOR signaling pathway

Hui-Yu Xu, Zhi-Wei Chen, Jin-Cai Hou, Feng-Xia Du, Ji-Cheng Liu
Pages: 212-218
Published online on: 31 October 2012

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Article

Transforming growth factor-β 1 enhances the invasiveness of breast cancer cells by inducing a Smad2-dependent epithelial-to-mesenchymal transition

Zhi-Dong Lv, Bin Kong, Jian-Guo Li, Hui-Li Qu, Xin-Gang Wang, Wei-Hong Cao, Xiao-Yi Liu, Yu Wang, Zhao-Chuan Yang, Hui-Mian Xu, Hai-Bo Wang
Pages: 219-225
Published online on: 30 October 2012

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Article

Correlation of telomere length shortening with TP53 somatic mutations, polymorphisms and allelic loss in breast tumors and esophageal cancer

Xiao-Dan Hao, Yue Yang, Xin Song, Xue-Ke Zhao, Li-Dong Wang, Jun-Dong He, Qing-Peng Kong, Nelson Leung Sang Tang, Ya-Ping Zhang
Pages: 226-236
Published online on: 22 October 2012

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Article

Norcantharidin suppresses cell growth and migration with enhanced anticancer activity of gefitinib and cisplatin in human non-small cell lung cancer cells

Ya-Chun Lee, Liang-Ming Lee, Chih-Hsin Yang, Anya Maan-Yuh Lin, Yi-Chia Huang, Chia-Chi Hsu, Meng-Shian Chen, Chin-Wen Chi, Pen-Hui Yin, Cheng-Deng Kuo, Jyh-Fei Liao, Hsin-Chen Lee
Pages: 237-243
Published online on: 31 October 2012

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Article

Growth inhibition and apoptosis of human B-cell lymphoma in vitro and in vivo by Bcl-2 short hairpin RNA

Yuchun Liu, Yongmei Shen, Chenhao Qin, Yizhen Shi, Guang Rong, Xilong Yu
Pages: 244-252
Published online on: 16 October 2012

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Article

Involvement of microRNAs in epigallocatechin gallate-mediated UVB protection in human dermal fibroblasts

In-Sook An, Sungkwan An, Seyeon Park, Sung Nae Lee, Seunghee Bae
Pages: 253-259
Published online on: 17 October 2012

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Article

Combination therapy with VEGFR2 and EGFR siRNA enhances the antitumor effect of cisplatin in non-small cell lung cancer xenografts

Shan Chen, Xiaoxia Liu, Wenfei Gong, Huan Yang, Daofei Luo, Xialin Zuo, Wenshi Li, Ping Wu, Li Liu, Qian Xu, Aimin Ji
Pages: 260-268
Published online on: 19 October 2012

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Article

SAHA down-regulates the expression of indoleamine 2,3-dioxygenase via inhibition of the JAK/STAT1 signaling pathway in gallbladder carcinoma cells

Peng Zhang, Guanmin Jiang, Jiao Gao, Lingling Li, Jun Du, Xingyuan Jiao
Pages: 269-275
Published online on: 08 October 2012

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Article

A novel recombinant immunocasp-6 fusion gene specifically and efficiently suppresses HER2-overexpressing osteosarcoma

Ben-Gen Zhou, Mei-Yuan Liu, Xiu-Chun Qiu, Yan-Ming Xu, Qing-Yu Fan, An-Gang Yang, Yu Zhang, Hong Xia
Pages: 276-282
Published online on: 05 November 2012

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Article

Downregulation of ubiquitin E3 ligase TNF receptor-associated factor 7 leads to stabilization of p53 in breast cancer

Lixin Wang, Lei Wang, Shuping Zhang, Guangbo Qu, Daoqiang Zhang, Shitao Li, Sijin Liu
Pages: 283-287
Published online on: 01 November 2012

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Article

WAP four-disulfide core domain protein 2 mediates the proliferation of human ovarian cancer cells through the regulation of growth- and apoptosis-associated genes

Yao Chen, Xia Mu, Suihai Wang, Liang Zhao, Yingsong Wu, Jiliang Li, Ming Li
Pages: 288-296
Published online on: 31 October 2012

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Article

Testicular orphan nuclear receptor 4-associated protein 16 promotes non-small cell lung carcinoma by activating estrogen receptor β and blocking testicular orphan nuclear receptor 2

Fang Fang, Qingfeng Zheng, Jianzhi Zhang, Bin Dong, Sainan Zhu, Xiaoyun Huang, Yang Wang, Bingtian Zhao, Shaolei Li, Hongchao Xiong, Jinfeng Chen, Nan Wu, Sonya Wei Song, Chawnshang Chang, Yue Yang
Pages: 297-305
Published online on: 26 October 2012

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Article

ETS variant 1 regulates matrix metalloproteinase-7 transcription in LNCaP prostate cancer cells

Sook Shin, Sangphil Oh, Seayoon An, Ralf Janknecht
Pages: 306-314
Published online on: 16 October 2012

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Article

WT1, WTX and CTNNB1 mutation analysis in 43 patients with sporadic Wilms' tumor

Leila C.A. Cardoso, Kelly R.L. De Souza, Adriana Helena De O. Reis, Raissa  Coelho Andrade, Alberto C. Britto , Maria A.F.D. De Lima, Anna  C.E. Dos Santos, Paulo S. De Faria, Sima Ferman, Héctor N. Seuánez, Fernando R. Vargas
Pages: 315-320
Published online on: 19 October 2012

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Article

Ex vivo 1H and 31P magnetic resonance spectroscopy as a means for tumor characterization in ovarian cancer patients

Yoram Abramov, Shani Carmi, Shaoul O. Anteby, Israel Ringel
Pages: 321-328
Published online on: 05 October 2012

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Article

Separate and concurrent use of 2-deoxy-D-glucose and 3-bromopyruvate in pancreatic cancer cells

Huijie Xiao, Shasha Li, Dapeng Zhang, Tongjun Liu, Ming Yu, Feng Wang
Pages: 329-334
Published online on: 17 October 2012

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Article

4-Methylumbelliferone leads to growth arrest and apoptosis in canine mammary tumor cells

Teruyoshi Saito, Dai Tamura, Tatsuro Nakamura, Yukihisa Makita, Hitomi Ariyama, Keiji Komiyama, Tomoko Yoshihara, Ryuji Asano
Pages: 335-342
Published online on: 23 October 2012

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Article

Effect of tumor gangliosides on tyrosine phosphorylation of p125FAK in platelet adhesion to collagen

Yi-Xin Chen, Xiao-Wen Chen, Chang-Gang Li, Li-Jie Yue, Hui-Rong Mai, Fei-Qiu Wen
Pages: 343-348
Published online on: 19 October 2012

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Article

Induction of apoptosis by D-limonene is mediated by inactivation of Akt in LS174T human colon cancer cells

Shu-Sheng Jia, Guang-Peng Xi, Ming Zhang, Yan-Bo Chen, Bo Lei, Xin-Shu Dong, Yan-Mei Yang
Pages: 349-354
Published online on: 19 October 2012

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Article

Plasma and tissue proteomic prognostic factors of response in primary breast cancer patients receiving neoadjuvant chemotherapy

J. Bonneterre, F. Révillion, C. Desauw, E. Blot, A. Kramar, C. Fournier, L. Hornez, J. P. Peyrat
Pages: 355-361
Published online on: 19 October 2012

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Article

The Notch1/cyclooxygenase-2/Snail/E-cadherin pathway is associated with hypoxia-induced hepatocellular carcinoma cell invasion and migration

Ling-Xiang Yu, Liang Zhou, Mo Li, Zhi-Wei Li, De-Sheng Wang, Shao-Geng Zhang
Pages: 362-370
Published online on: 23 October 2012

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Article

Indirubin-3'-oxime induces mitochondrial dysfunction and triggers growth inhibition and cell cycle arrest in human neuroblastoma cells

Xue-Mei Liao, Kwok-Nam Leung
Pages: 371-379
Published online on: 19 October 2012

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Article

Curcumin enhances the response of non-Hodgkin's lymphoma cells to ionizing radiation through further induction of cell cycle arrest at the G2/M phase and inhibition of mTOR phosphorylation

Qiao Qiao, Yuanjun Jiang, Guang Li
Pages: 380-386
Published online on: 19 October 2012

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Article

Growth inhibition of Tax-activated human Jurkat leukemia T cells by all-trans retinoic acid requires JNK-1 inhibition

Eduardo Parra, Luis Gutiérrez
Pages: 387-393
Published online on: 26 October 2012

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Article

Knockdown of Nrf2 enhances autophagy induced by temozolomide in U251 human glioma cell line

Yuan Zhou, Han-Dong Wang, Lin Zhu, Zi-Xiang Cong, Ning Li, Xiang-Jun Ji, Hao Pan, Jia-Wei Wang, Wan-Chun Li
Pages: 394-400
Published online on: 31 October 2012

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Journal Cover
January-2026 Volume 55 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Harnessing ferroptosis for cancer therapy: Mechanisms and therapeutic strategies (Review)

Nabil Mouawad, Nour El Jaafari, Mirvat El Sibai, Ralph J. Abi-Habib
Article Number: 24
Published online on: 24 November 2025

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Expression of Concern Open Access

[Expression of Concern] Promoter methylation of death‑associated protein kinase and its role in irradiation response in cervical cancer

Rebecca Ching-Yu Leung, Stephanie Si Liu, Kelvin Yuen-Kwong Chan, Kar-Fai Tam, Kar-Loen Chan, Ling-Chui Wong, Hextan Yuen-Sheung Ngan
Article Number: 23
Published online on: 24 November 2025

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Article Open Access

Oxaliplatin resistance in pancreatic ductal adenocarcinoma is non‑significantly mediated by diminished drug uptake but is highly linked to a poor apoptotic response to the cytotoxic threat

Hellen Röttgen, Lana Theurer, Teresa Peccerella, Ketaki Sandu, Johanna Weiss, Jürgen Burhenne, John P. Neoptolemos, Beate Köberle, Dirk Theile
Article Number: 22
Published online on: 19 November 2025

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Correction Open Access

[Corrigendum] Src homology phosphotyrosyl phosphatase 2 mediates cisplatin‑related drug resistance by inhibiting apoptosis and activating the Ras/PI3K/Akt1/survivin pathway in lung cancer cells

Chunlan Tang, Hu Luo, Dan Luo, Heping Yang, Xiangdong Zhou
Article Number: 21
Published online on: 19 November 2025

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S100B drives glioblastoma invasion and migration through TGF‑β2‑mediated epithelial‑mesenchymal transition

Xuemei Liao, Yuan Xu, Honghong Zhou, Qin Yi, Shifang Dong, Bin Tan
Article Number: 20
Published online on: 19 November 2025

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Review Open Access

Role of the SOX family in non‑small cell lung cancer: Molecular mechanisms and therapeutic implications (Review)

Kaiwei Wang, Yaoqi Li, Zhening Guo, Lin Song, Xiaoliang Ding, Linsheng Liu, Tao Hu, Yicong Bian, Chenrong Huang, Liyan Miao
Article Number: 19
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑18a enhances the radiosensitivity of cervical cancer cells by promoting radiation‑induced apoptosis

Sha Liu, Xiaofen Pan, Qin Yang, Lu Wen, Yao Jiang, Yingchao Zhao, Guiling Li
Article Number: 18
Published online on: 17 November 2025

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Review Open Access

Role of histone deacetylases in blood cancer: Exploring peptide‑based inhibitors as therapeutic strategies for leukemia treatment (Review)

Yaneenart Suwanwong, Phornthip Ploensil
Article Number: 17
Published online on: 14 November 2025

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The multidimensional regulatory network of the PD‑1/PD‑L1 axis in the esophageal squamous cell carcinoma microenvironment: Implications for novel combination therapies and precision immunotherapy (Review)

Haoyue Lai, Lu Qi, Zhixuan Lin, Zhongwen Li
Article Number: 16
Published online on: 13 November 2025

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Review Open Access

From modification to malignancy: Bridging acetylation mechanisms and therapeutic innovations in melanoma (Review)

Jingwen Wu, Xuxia Cai, Zimo Zhu, Xiahong Li, Kaoyuan Zhang, Chenchen Wu, Bo Yu, Cong Huang
Article Number: 15
Published online on: 12 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑92b promotes tumor growth and activation of NF‑κB signaling via regulation of NLK in oral squamous cell carcinoma

Zhiming Liu, Cynthia Diep, Tiantian Mao, Li Huang, Robert Merrill, Zhouwen Zhang, Youjian Peng
Article Number: 14
Published online on: 11 November 2025

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C‑terminal HSP90 inhibitor NCT‑58 impairs the cancer stem‑like phenotype and enhances chemotherapy efficacy in TNBC

Eunsun Jung, Yoon-Jae Kim, Kyoungmin Lee, Seojin Jang, Soeun Park, Eunhye Oh, Minsu Park, Seongjae Kim, Dongmi Ko, Yong Koo Kang, Kee Dal Nam, Lee Farrand, Cong-Truong Nguyen, Minh Thanh La, Jihyae Ann, Jeewoo Lee, Ji Young Kim, Jae Hong Seo
Article Number: 13
Published online on: 11 November 2025

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Correction Open Access

[Corrigendum] Compound 225# inhibits the proliferation of human colorectal cancer cells by promoting cell cycle arrest and apoptosis induction

Xiaoxue Zhang, Liujun He, Yong Li, Yifei Qiu, Wujing Hu, Wanying Lu, Huihui Du, Donglin Yang
Article Number: 12
Published online on: 06 November 2025

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Review Open Access

Immune system, inflammatory response, and regulated cell death in breast cancer research (Review)

Guangyao Li, Binghui Jin, Jialin Zhou, Shifeng Fang, Zhe Fan
Article Number: 11
Published online on: 05 November 2025

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Retraction Open Access

[Retracted] Uvangoletin induces mitochondria‑mediated apoptosis in HL‑60 cells in vitro and in vivo without adverse reactions of myelosuppression, leucopenia and gastrointestinal tract disturbances

Zhuanzhen Zheng, Zhenhua Qiao, Rong Gong, Yalin Wang, Yiqun Zhang, Yanping Ma, Li Zhang, Yujin Lu, Bo Jiang, Guoxia Li, Chunxia Dong, Wenliang Chen
Article Number: 10
Published online on: 03 November 2025

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Article Open Access

Characterization of the anticancer effect of mebendazole and its interaction with standard cytotoxic drugs in patient tumor cells ex vivo and in an in vivo mouse model

Sharmineh Mansoori, Kristin Blom, Claes Andersson, Mårten Fryknäs, Rolf Larsson, Peter Nygren
Article Number: 9
Published online on: 31 October 2025

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Correction Open Access

[Corrigendum] Gemcitabine combined with an engineered oncolytic vaccinia virus exhibits a synergistic suppressive effect on the tumor growth of pancreatic cancer

Wanyuan Chen, Weimin Fan, Guoqing Ru, Fang Huang, Xiaming Lu, Xin Zhang, Xiaozhou Mou, Shibing Wang
Article Number: 8
Published online on: 30 October 2025

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Article Open Access

CD44 knockdown and TGF‑β inhibition modulate cell proliferation and invasion in claudin‑low breast cancer cells

Ryoichi Matsunuma, Kazuo Kinoshita, Sae Imada, Shoko Sato, Ryosuke Hayami, Michiko Tsuneizumi
Article Number: 7
Published online on: 30 October 2025

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Retraction Open Access

[Retracted] MicroRNA‑302a targets GAB2 to suppress cell proliferation, migration and invasion of glioma

Jiuhong Ma, Jia Yu, Jingmei Liu, Xing Yang, Miao Lou, Jinghui Liu, Fuqiang Feng, Peigang Ji, Liang Wang
Article Number: 6
Published online on: 27 October 2025

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Article Open Access

LRRC59 inhibits perk pathway‑induced apoptosis and promotes cell proliferation, migration and invasion in colorectal cancer cells

Xingdong Hou, Yuting Wang, Yuzhuo Chen, Peiyan Zhong, Guangzhi Wang, Baicheng Li, Bowei Lu, Hanyu Jiang, Shili Ning
Article Number: 5
Published online on: 23 October 2025

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Article Open Access

Comparative analysis of the efficacy and safety of antibody‑drug conjugates, radionuclide‑drug conjugates and their combination targeting claudin 18.2 in gastric cancer treatment

Huan Du, Xiao-Fei Hao, Bin-Wei Lin, Yu Zhang, Luo Rui, Jing Wang, Ming-Ming Tang, De-Cai Wang, Yi-Han Zhu, Jie Li, Tang-Zhi Dai, Yuchuan Yang, Xia Yang, Xiaobo Du
Article Number: 4
Published online on: 22 October 2025

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Expression of Concern Open Access

[Expression of Concern] CDKN3 is an independent prognostic factor and promotes ovarian carcinoma cell proliferation in ovarian cancer

Tianren Li, Hui Xue, Yi Guo, Kejun Guo
Article Number: 3
Published online on: 16 October 2025

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Review Open Access

Platelet‑circulating tumor cell crosstalk: A pivotal target in cancer diagnosis and therapy (Review)

Lifang Zhang, Ye Yuan, Yan Deng, Lin Wang, Fenghua Chen
Article Number: 2
Published online on: 15 October 2025

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Expression of Concern Open Access

[Expression of Concern] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 1
Published online on: 14 October 2025

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Journal Cover
February-2026 Volume 55 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Alternative splicing in cancer drug resistance: Mechanisms and therapeutic prospects (Review)

Wenpu Zhu, Zikun Wu, Chai Luv, Banghe Bao, Weijie Zhao, Guanglong Chen, Hang Yang, Huihan Ai, Faqiang Liu, Zhi Li
Article Number: 31
Published online on: 05 December 2025

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Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells

Liangliang Jin, Li Wei, Junrui Hua, Rong Zhang, Jiaxin Chen, Jinpeng He, Yanli Yang
Article Number: 30
Published online on: 04 December 2025

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Review

Beyond eradication: Therapeutic reprogramming strategies for cancer normalization (Review)

Aliasgar Shahiwala
Article Number: 29
Published online on: 04 December 2025

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Article Open Access

Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy

Rui Zheng, Yusi Liu, Sen Zhou, Guimei Liu, Xiaobin Liu, Yiyuan Yang, Yufu Zhang
Article Number: 28
Published online on: 04 December 2025

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Retraction Open Access

[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Article Number: 27
Published online on: 04 December 2025

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Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma

Yuto Kitano, Tomoharu Miyashita, Takeo Shimasaki, Isamu Makino, Yoshio Endo, Yasuhiko Yamamoto, Noriyuki Inaki, Shintaro Yagi
Article Number: 26
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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