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Molecular Medicine Reports
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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
November-2018 Volume 18 Issue 5

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Journal Metrics

Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

Roles of endoplasmic reticulum stress and autophagy on H2O2‑induced oxidative stress injury in HepG2 cells

Zhiming Wu, Huangen Wang, Sunyang Fang, Chaoyang Xu
Pages: 4163-4174
Published online on: 03 September 2018

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Article Open Access

Anti‑breast cancer activity of selected 1,3,5‑triazines via modulation of EGFR‑TK

Weixin Yan, Yiyang Zhao, Jianrong He
Pages: 4175-4184
Published online on: 24 August 2018

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Article Open Access

Bioinformatics analyses of significant genes, related pathways and candidate prognostic biomarkers in glioblastoma

Lingqi Zhou, Hai Tang, Fang Wang, Lizhi Chen, Shanshan Ou, Tong Wu, Jie Xu, Kaihua Guo
Pages: 4185-4196
Published online on: 21 August 2018

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Article Open Access

Network analysis of membranous glomerulonephritis based on metabolomics data

Amir Taherkhani, Shiva Kalantari, Afsaneh Arefi Oskouie, Mohsen Nafar, Mohammad Taghizadeh, Koorosh Tabar
Pages: 4197-4212
Published online on: 12 September 2018

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Article Open Access

Effect of chemokine CC ligand 2 (CCL2) on α‑synuclein‑induced microglia proliferation and neuronal apoptosis

Lijun Zhang, Pengju Ma, Qingkai Guan, Lei Meng, Linlin Su, Lina Wang, Bin Yuan
Pages: 4213-4218
Published online on: 10 September 2018

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Article Open Access

Protective effects of α‑2‑macroglobulin on human bone marrow mesenchymal stem cells in radiation injury

Yang Liu, Wanting Cao, Xiangbo Kong, Jie Li, Xueying Chen, Yaping Ge, Wanzhen Zhong, Silian Fang
Pages: 4219-4228
Published online on: 04 September 2018

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Article Open Access

Comprehensive analysis of multi Ewing sarcoma microarray datasets identifies several prognosis biomarkers

Xuqing Yin, Jiubo Sun, Haiyang Zhang, Shuai Wang
Pages: 4229-4238
Published online on: 03 September 2018

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Article Open Access

Long non‑coding RNA ferritin heavy polypeptide 1 pseudogene 3 controls glioma cell proliferation and apoptosis via regulation of the microRNA‑224‑5p/tumor protein D52 axis

Yongqiang Zhang, Ying Li, Jing Wang, Ping Lei
Pages: 4239-4246
Published online on: 14 September 2018

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Article Open Access

Distribution and prognostic value of tumor‑infiltrating T cells in breast cancer

Shaoda Meng, Li Li, Meiling Zhou, Wanjie Jiang, Heng Niu, Kunxian Yang
Pages: 4247-4258
Published online on: 05 September 2018

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Article Open Access

BACE1 gene silencing alleviates isoflurane anesthesia‑induced postoperative cognitive dysfunction in immature rats by activating the PI3K/Akt signaling pathway

Ying‑Bin Wang, Jian‑Qin Xie, Wei Liu, Rong‑Zhi Zhang, Sheng‑Hui Huang, Yan‑Hong Xing
Pages: 4259-4270
Published online on: 04 September 2018

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Article Open Access

Genetic mutation of familial dilated cardiomyopathy based on next‑generation semiconductor sequencing

Xin‑Fu Lin, Jie‑Wei Luo, Gui Liu, Yao‑Bin Zhu, Zhao Jin, Xing Lin
Pages: 4271-4280
Published online on: 05 September 2018

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Article Open Access

Combination of pristimerin and paclitaxel additively induces autophagy in human breast cancer cells via ERK1/2 regulation

Younju Lee, Jinuk Na, Myung Sun Lee, Eun Young Cha, Ji Young Sul, Jun Beom Park, Jin Sun Lee
Pages: 4281-4288
Published online on: 14 September 2018

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Article Open Access

Pharmacological basis for application of scutellarin in Alzheimer's disease: Antioxidation and antiapoptosis

Xinyu Hu, Shanshan Teng, Jiawei He, Xiaoqi Sun, Mingzhao Du, Ling Kou, Xiaofeng Wang
Pages: 4289-4296
Published online on: 13 September 2018

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Article Open Access

Elevated methylation of OPRM1 and OPRL1 genes in Alzheimer's disease

Chunshuang Xu, Guili Liu, Huihui Ji, Weihua Chen, Dongjun Dai, Zhongming Chen, Dongsheng Zhou, Lei Xu, Haochang Hu, Wei Cui, Lan Chang, Qin Zha, Liping Li, Shiwei Duan, Qinwen Wang
Pages: 4297-4302
Published online on: 24 August 2018

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Article Open Access

Effect of emodin on T cell subsets in NOD mice with NaI‑induced experimental autoimmune thyroiditis

Huaqin Sun, Zhipeng Ye, Ning Li, Fa Jin, Jiuliang Yan, Keren Wu
Pages: 4303-4312
Published online on: 03 September 2018

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Article Open Access

Modular bioinformatics analysis demonstrates that a Toll‑like receptor signaling pathway is involved in the regulation of macrophage polarization

Biao Ma, Yang Yang, Zhituo Li, Dali Zhao, Weihui Zhang, Yanfeng Jiang, Dongbo Xue
Pages: 4313-4320
Published online on: 14 September 2018

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Article Open Access

Cytoprotective effects of the medicinal herb Astragalus membranaceus on lipopolysaccharide‑exposed cells

Xian Wu, Wei Zhou, Qingshuang Wei, Peng Chen, Yan Li
Pages: 4321-4327
Published online on: 14 September 2018

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Article Open Access

Protein phosphatase 2A regulates the p38 signaling pathway to affect the migration of astrocytes

Lijun Zhang, Pengju Ma, Qingkai Guan, Lei Meng, Linlin Su, Lina Wang, Jianhua Zhao, Sibei Ji
Pages: 4328-4334
Published online on: 24 August 2018

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Article Open Access

Deletion of poly(ADP‑ribose) polymerase-1 changes the composition of the microbiome in the gut

András Vida, Gábor Kardos, Tünde Kovács, Balázs L. Bodrogi, Péter Bai
Pages: 4335-4341
Published online on: 10 September 2018

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Article Open Access

Amino acid starvation promotes podocyte autophagy through mammalian target of rapamycin inhibition and transcription factor EB activation

Yuanhan Chen, Xingchen Zhao, Jiaxin Li, Li Zhang, Ruizhao Li, Hong Zhang, Ruyi Liao, Shuangxin Liu, Wei Shi, Xinling Liang
Pages: 4342-4348
Published online on: 03 September 2018

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Article Open Access

Angiotensin II upregulates cyclophilin A by enhancing ROS production in rat cardiomyocytes

Hangyu Tian, Dan Yu, Yan Hu, Pan Zhang, Yang Yang, Qiang Hu, Ming Li
Pages: 4349-4355
Published online on: 04 September 2018

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Article Open Access

Downregulation of FOXK2 is associated with poor prognosis in patients with gastric cancer

Xi Liu, Xiaodong Wei, Wei Niu, Dong Wang, Bo Wang, Hao Zhuang
Pages: 4356-4364
Published online on: 07 September 2018

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Article Open Access

Molecular pathogenesis involved in human idiopathic pulmonary fibrosis based on an integrated microRNA‑mRNA interaction network

Lijing Wang, Wei Huang, Lemeng Zhang, Qiong Chen, Hongjun Zhao
Pages: 4365-4373
Published online on: 05 September 2018

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Article Open Access

CXCL12 induces migration of oligodendrocyte precursor cells through the CXCR4‑activated MEK/ERK and PI3K/AKT pathways

Yongyang Tian, Hong Yin, Xi Deng, Beichuan Tang, Xianjun Ren, Tao Jiang
Pages: 4374-4380
Published online on: 03 September 2018

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Article Open Access

Dicer affects cisplatin‑mediated apoptosis in epithelial ovarian cancer cells

Xi Wang, Hui Chen, Yiping Wen, Xiaoxin Yang, Qing Han, Ping Jiang, Zaiju Huang, Jing Cai, Zehua Wang
Pages: 4381-4387
Published online on: 04 September 2018

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Article Open Access

Streptozotocin‑induced diabetic mice exhibit reduced experimental choroidal neovascularization but not corneal neovascularization

Gaoqin Liu, Lei Chen, Qinhua Cai, Hongya Wu, Zhigang Chen, Xueguang Zhang, Peirong Lu
Pages: 4388-4398
Published online on: 03 September 2018

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Article Open Access

Regulation of the NLRP3 inflammasome and macrophage pyroptosis by the p38 MAPK signaling pathway in a mouse model of acute lung injury

Dandan Li, Weiying Ren, Zhilong Jiang, Lei Zhu
Pages: 4399-4409
Published online on: 24 August 2018

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Article Open Access

Estrogen restricts the apoptosis of endometrial stromal cells by promoting TSLP secretion

Hui‑Li Yang, Kai‑Kai Chang, Jie Mei, Wen‑Jie Zhou, Li‑Bing Liu, Li Yao, Yi Meng, Ming‑Yan Wang, Si‑Yao Ha, Zhen‑Zhen Lai, Jiang‑Feng Ye, Da‑Jin Li, Ming‑Qing Li
Pages: 4410-4416
Published online on: 24 August 2018

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Article Open Access

Comparing the role of Ginkgolide B and Ginkgolide K on cultured astrocytes exposed to oxygen‑glucose deprivation

Wen‑Bo Yu, Liang Cao, Yan‑Yin Zhao, Wei Xiao, Bao‑Guo Xiao
Pages: 4417-4427
Published online on: 04 September 2018

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Article Open Access

FKBP11 protects intestinal epithelial cells against inflammation‑induced apoptosis via the JNK‑caspase pathway in Crohn's disease Corrigendum in /10.3892/mmr.2024.13172

Xiaotong Wang, Xiaopeng Cui, Chuanwu Zhu, Ming Li, Juan Zhao, Zhongyi Shen, Xiaohang Shan, Liang Wang, Han Wu, Yanting Shen, You Ni, Dongmei Zhang, Guoxiong Zhou
Pages: 4428-4438
Published online on: 14 September 2018

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Article Open Access

Two Paired Box 6 mutations identified in Chinese patients with classic congenital aniridia and cataract

Ying Lin, Hongbin Gao, Yi Zhu, Chuan Chen, Tao Li, Bingqian Liu, Cancan Lyu, Ying Huang, Haichun Li, Qingxiu Wu, Chenjin Jin, Xiaoling Liang, Xinhua Huang, Lin Lu
Pages: 4439-4445
Published online on: 10 September 2018

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Article Open Access

Using Illumina Infinium HumanMethylation 450K BeadChip to explore genome‑wide DNA methylation profiles in a human hepatocellular carcinoma cell line

Ning Sun, Jialin Zhang, Chengshuo Zhang, Yue Shi, Bochao Zhao, Ao Jiao, Baomin Chen
Pages: 4446-4456
Published online on: 03 September 2018

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Article Open Access

Adoptive transfer of xenoantigen‑stimulated T cell receptor Vβ‑restricted human regulatory T cells prevents porcine islet xenograft rejection in humanized mice

Xi Jin, Min Hu, Lina Gong, Huifang Li, Yan Wang, Ming Ji, Hong Li
Pages: 4457-4467
Published online on: 10 September 2018

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Article Open Access

Protective effect of berberine on aconite‑induced myocardial injury and the associated mechanisms

Xueyan Chen, Huicai Guo, Qing Li, Yu Zhang, Huanlong Liu, Xiaofei Zhang, Kerang Xie, Zhongning Zhu, Qingfeng Miao, Suwen Su
Pages: 4468-4476
Published online on: 12 September 2018

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Article Open Access

Platelet‑rich fibrin exudate promotes the proliferation and osteogenic differentiation of human periodontal ligament cells in vitro

Xiaoju Li, Huixiao Yang, Zijiian Zhang, Zhonghai Yan, Huling Lv, Yan Zhang, Bin Wu
Pages: 4477-4485
Published online on: 10 September 2018

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Article Open Access

Role of the Rho/ROCK signaling pathway in the protective effects of fasudil against acute lung injury in septic rats

Yu Wang, Xiaofeng Wang, Wei Liu, Lichun Zhang
Pages: 4486-4498
Published online on: 03 September 2018

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Article Open Access

Identification of key genes and associated pathways in KIT/PDGFRA wild‑type gastrointestinal stromal tumors through bioinformatics analysis

Wen‑Jie Wang, Hong‑Tao Li, Jian‑Ping Yu, Yu‑Min Li, Xiao‑Peng Han, Peng Chen, Wen‑Wen Yu, Wei‑Kai Chen, Zuo‑Yi Jiao, Hong‑Bin Liu
Pages: 4499-4515
Published online on: 05 September 2018

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Article Open Access

Protective effects of taurine against inflammation, apoptosis, and oxidative stress in brain injury

Xiaoli Niu, Simin Zheng, Hongtao Liu, Siyuan Li
Pages: 4516-4522
Published online on: 06 September 2018

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Article Open Access

Complement depletion with cobra venom factor alleviates acute hepatic injury induced by ischemia‑reperfusion

Bing Wang, Hua Xu, Jian Li, Hong‑Mei Gao, Ying‑Hong Xing, Zhu Lin, Hong‑Jie Li, Yong‑Qiang Wang, Shu‑Hua Cao
Pages: 4523-4529
Published online on: 14 September 2018

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Article

Aldehyde dehydrogenase activity in cryopreserved cord blood cells for quality assessment prior to transplantation

Junko Ikemoto, Satoshi Yoshihara, Tamami Kobayashi, Shunro Kai, Yoshihiro Fujimori
Pages: 4530-4534
Published online on: 13 September 2018

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Article

Theanine, an antitumor promoter, induces apoptosis of tumor cells via the mitochondrial pathway

Yinqiang Xin, Peiling Ben, Qi Wang, Yanyan Zhu, Zhimin Yin, Lan Luo
Pages: 4535-4542
Published online on: 05 September 2018

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Article

Expression and clinical significance of ubiquitin‑specific‑processing protease 34 in diffuse large B‑cell lymphoma

Chunyao Li, Lanshan Huang, Huiping Lu, Wei Wang, Gang Chen, Yongyao Gu, Qianping Zhou, Zhigang Peng, Zhenbo Feng
Pages: 4543-4554
Published online on: 03 September 2018

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Article

Epigallocatechin‑3‑gallate protects against secondary osteoporosis in a mouse model via the Wnt/β‑catenin signaling pathway

Jiancheng Xi, Qinggui Li, Xiaobo Luo, Jinlong Li, Lixin Guo, Haibin Xue, Guangsen Wu
Pages: 4555-4562
Published online on: 03 September 2018

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Article

miRNA‑328 overexpression confers cisplatin resistance in non‑small cell lung cancer via targeting of PTEN

Chunmei Wang, Shijun Wang, Feng'e Ma, Weidan Zhang
Pages: 4563-4570
Published online on: 12 September 2018

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Article

Silencing of perilipin by short hairpin RNA inhibits proliferation and induces apoptosis in liposarcoma cells

Ling‑Xin Meng, Yu‑Xiu Zheng, Mao‑Lei He, Xiao‑Ming Zhou, Shu‑Yan Sun, Zhao‑Jun Ding, Qin Meng, Bing‑Cheng Li, Yan‑Wei Sun
Pages: 4571-4576
Published online on: 05 September 2018

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Article

Protection of insulin‑like growth factor 1 on experimental peripheral neuropathy in diabetic mice

Hua Wang, Hao Zhang, Fuming Cao, Jiaping Lu, Jin Tang, Huizhi Li, Yiyun Zhang, Bo Feng, Zhaosheng Tang
Pages: 4577-4586
Published online on: 03 September 2018

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Article

Bafilomycin A1 alleviates depression‑like symptoms in chronic unpredictable mild stress rats

Zhijian Wang, Shengbing Liu, Weiwei Pan, Yanjun Guo, Zhongfei Shen
Pages: 4587-4594
Published online on: 03 September 2018

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Article

Huwe1 is a novel mediator of protection of neural progenitor L2.3 cells against oxygen‑glucose deprivation injury

Xiaoqin Jiang, Jiyun Yang, Hedong Li, Yi Qu, Wenming Xu, Haiyan Yu, Yu Tong
Pages: 4595-4602
Published online on: 03 September 2018

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Article

Cantharidin inhibits melanoma cell proliferation via the miR‑21‑mediated PTEN pathway

Zhen Mu, Qing Sun
Pages: 4603-4610
Published online on: 03 September 2018

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Article

Analysis of virulence diversity of 73 Helicobacter pylori strains isolated in Guizhou province, China

Lin Yin, Fang Liu, Changcheng Guo, Qiong Wang, Ke Pan, Liangbi Xu, Yan Xiong, Yingting Chen, Zhenghong Chen
Pages: 4611-4620
Published online on: 05 September 2018

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Article

miR‑3120‑5p acts as a diagnostic biomarker in non‑small cell lung cancer and promotes cancer cell proliferation and invasion by targeting KLF4

Hongwei Xu, Quan Wen
Pages: 4621-4628
Published online on: 04 September 2018

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Article

Association between the methylation of six apoptosis‑associated genes with autism spectrum disorder

Yuanzhi Zhao, Cong Zhou, Hang Yu, Wenwu Zhang, Fang Cheng, Haihang Yu, Dongsheng Zhou, Bin Li, Jing Liu, Jie Dai, Jie Zhong, Min Chen, Tianyi Huang, Ranran Pan, Shiwei Duan, Zhenyu Hu
Pages: 4629-4634
Published online on: 10 September 2018

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Article

Inhibition of CCL19 benefits non‑alcoholic fatty liver disease by inhibiting TLR4/NF‑κB‑p65 signaling

Jiajing Zhao, Yingjue Wang, Xi Wu, Ping Tong, Yaohan Yue, Shurong Gao, Dongping Huang, Jianwei Huang
Pages: 4635-4642
Published online on: 14 September 2018

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Article

Application of medical adhesive inhibits intimal hyperplasia involving the downregulation of ERK1/2 and eNOS levels

Shoudong Chai, Yang Yu, Haiming Li, Mingxin Gao, Bo Li , Chengxiong Gu
Pages: 4643-4649
Published online on: 17 September 2018

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Article

Post‑transplant lymphoproliferative disorder in hematopoietic stem cell transplant patients: A single center retrospective study between 2005 and 2012

Joana Marinho‑Dias, João Lobo, Rui Henrique, Inês Baldaque, Carlos Pinho‑Vaz, Luísa Regadas, Rosa Branca, Fernando Campilho, António Campos Jr, Rui Medeiros, Hugo Sousa
Pages: 4650-4656
Published online on: 03 September 2018

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Article

Sevoflurane‑induced neurotoxicity is driven by OXR1 post‑transcriptional downregulation involving hsa‑miR‑302e

Leilei Yang, Qian Shen, Yanqiong Xia, Xueheng Lei, Jian Peng
Pages: 4657-4665
Published online on: 03 September 2018

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Article

Attenuated endothelial function is associated with decreased endothelial progenitor cells and nitric oxide in premenopausal diabetic women

Juan Liu, Da‑Jun Hu, Huiyang Yan, Jianbin Liu, Xixong Ai, Zi Ren, Haitao Zeng, Hao He, Zhen Yang
Pages: 4666-4674
Published online on: 04 September 2018

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Article

Ursolic acid alleviates inflammation and against diabetes‑induced nephropathy through TLR4‑mediated inflammatory pathway

Jian Li, Nan Li, Shuangtong Yan, Minyan Liu, Banruo Sun, Yanhui Lu, Yinghong Shao
Pages: 4675-4681
Published online on: 03 September 2018

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Article

SFRP5 serves a beneficial role in arterial aging by inhibiting the proliferation, migration and inflammation of smooth muscle cells

Jiadela Teliewubai, Hongwei Ji, Yuyan Lu, Bin Bai, Shikai Yu, Chen Chi, Yawei Xu, Yi Zhang
Pages: 4682-4690
Published online on: 07 September 2018

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Article

Immunization with lentiviral vector‑modified dendritic cells encoding ubiquitinated hepatitis B core antigen promotes Th1 differentiation and antiviral immunity by enhancing p38 MAPK and JNK activation in HBV transgenic mice

Shenglan Dai, Xiaohua Chen, Yongsheng Yu, Guoqing Zang, Zhenghao Tang
Pages: 4691-4699
Published online on: 14 September 2018

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Article

Molecular mechanisms regarding potassium bromate‑induced cardiac hypertrophy without apoptosis in H9c2 cells

Shu‑Chun Kuo, Yingxiao Li, Yung‑Ze Cheng, Wei‑Jing Lee, Juei‑Tang Cheng, Kai‑Chun Cheng
Pages: 4700-4708
Published online on: 10 September 2018

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Article

Structure‑activity associations in novel farrerol derivatives with vasorelaxant properties

Xiaomin Hou, Xiaojiang Qin, Qingshan Li
Pages: 4709-4715
Published online on: 03 September 2018

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Case Report

Sarcomatoid carcinoma of the pancreas: A case report and review of the literature

Yingjun Xie, Yien Xiang, Dan Zhang, Xiaoxiao Yao, Jiyao Sheng, Yongsheng Yang, Xuewen Zhang
Pages: 4716-4724
Published online on: 14 September 2018

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Article

Long noncoding RNA LINC00978 promotes cell proliferation and invasion in non‑small cell lung cancer by inhibiting miR‑6754‑5p

Xinlei Li, Yang Ren, Tie Zuo
Pages: 4725-4732
Published online on: 06 September 2018

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Article

Acute stimulatory effect of tumor necrosis factor on the basolateral 50 pS K channels in the thick ascending limb of the rat kidney

Guoyan Zhang, Shiliang Gui, Weiqun Wang, Dexin Meng, Qingmin Meng, Haiyan Luan, Rixin Zhao, Jiatian Zhang, Hongyu Sui
Pages: 4733-4738
Published online on: 10 September 2018

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Article

Silencing of pantothenate kinase 2 reduces endothelial cell angiogenesis

Francesca Pagani, Akansha Trivedi, Deepak Khatri, Daniela Zizioli, Emirena Garrafa, Stefania Mitola, Dario Finazzi
Pages: 4739-4746
Published online on: 13 September 2018

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Article

miR‑501‑3p sensitizes glioma cells to cisplatin by targeting MYCN

Chuan‑Gang Zhang, Fan Yang, Yan‑Hua Li, Yan Sun, Xue‑Jian Liu, Xia Wu
Pages: 4747-4752
Published online on: 05 September 2018

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Article

Celastrol inhibits glucocorticoid‑induced osteoporosis in rat via the PI3K/AKT and Wnt signaling pathways

Jiancheng Xi, Qinggui Li, Xiaobo Luo, Yipeng Wang, Jinlong Li, Lixin Guo, Guangsen Wu
Pages: 4753-4759
Published online on: 03 September 2018

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Article

LIMD2 targeted by miR‑34a promotes the proliferation and invasion of non‑small cell lung cancer cells

Fei Wang, Zhaoguo Li, Lei Xu, Yongchao Li, Yi Li, Xingbo Zhang, Yue Wang, Dazhong Liu
Pages: 4760-4766
Published online on: 06 September 2018

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Retraction Open Access

[Retracted] BIRC5 is a novel target of peroxisome proliferator‑activated receptor γ in brain microvascular endothelium cells during cerebral ischemia

Mingjing Xu, Xianli Yang, Qing Zeng, He He, Pengcheng Lu, Guozhi Huang
Pages: 4767-4767
Published online on: 22 August 2018

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Correction Open Access

[Corrigendum] Neurotoxin β‑N‑methylamino‑L‑alanine induces endoplasmic reticulum stress‑mediated neuronal apoptosis

Haiying Shen, Kiyoon Kim, Yoojung Oh, Kyung Sik Yoon, Hyung Hwan Baik, Sung Soo Kim, Joohun Ha, Insug Kang, Wonchae Choe
Pages: 4768-4768
Published online on: 12 September 2018

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Journal Cover
November-2026 Volume 34 Issue 5

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Journal Metrics

Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

Research on the role and mechanism of SLC7A5 in idiopathic pulmonary fibrosis

Menghan Wang, Yao Yu, Zhaoyu Liu, Dandan Xu, Yupeng Li, Xing Zou, Ning Shan, Xining Liu, Ce Shi, Hong Chen
Article Number: 323
Published online on: 01 October 2026

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Review Open Access

Electroencephalography research in neuropathic pain (Review)

Lanling Zhou, Nianshun Liao, Hongmei Wang, Jiaxi Zhao, Haijun Jiang, Shihua Dang, Sixun Yu, Haifeng Shu, Xin Chen
Article Number: 322
Published online on: 25 September 2026

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Review Open Access

BMAL1 in cardiovascular diseases: Molecular mechanisms, circadian regulation and translational perspectives (Review)

Yu Liang, Tingjin Chen, Xuemei Wen, Dan Liu, Zhongjian Zhang, Weiqing Li, Hengdi Zhang
Article Number: 321
Published online on: 24 September 2026

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Review Open Access

Progress on quinoline‑based antitumour agents: Mechanistic insights and optimization strategies (Review)

Yuwen Zeng, Yutong Yan, Shiye Wu, Wanshan Wu, Ke Chen, Youyi Lai, Qing Ye, Nan Zhang, Yuanyuan Zhou
Article Number: 320
Published online on: 23 September 2026

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Review Open Access

Lactylation in gastric cancer: From mechanisms to clinical applications (Review)

Yuliang Fang, Peng Chen, Yuhong Gao, Yanpiao Li, Xue Li
Article Number: 319
Published online on: 23 September 2026

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Article Open Access

Sleep deprivation exacerbates lens‑induced myopia in association with ERK/NF‑κB pathway activation

Xueli Yang, Zhou Zhang, Chengbai Zhu, Jianbo Li, Wenting Gong, Ruirui Yang, Lipeng Guan
Article Number: 318
Published online on: 22 September 2026

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Review Open Access

Advances in biomarkers of benzene exposure and toxicity: From mechanistic insights to occupational health applications (Review)

Yuanshe Huang, Zhenjun Xi, Jingxin Mao, Xiaobing Li
Article Number: 317
Published online on: 21 September 2026

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Retraction Open Access

[Retracted] CALB1 enhances the interaction between p53 and MDM2, and inhibits the senescence of ovarian cancer cells

Long-Qiao Cao, Ya-Nan Wang, Ming Liang, Mei-Zhou Pan
Article Number: 316
Published online on: 21 September 2026

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Review Open Access

Artemisinin and its derivatives for metabolic syndrome: From multi‑target mechanisms to translational opportunities (Review)

Shuo Cao, Mo Yang, Siyu Qu, Jinsong Wu, Jiaheng Li, Ying Zhao
Article Number: 315
Published online on: 17 September 2026

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Article Open Access

Demethylase FTO attenuates atherosclerotic plaque via upregulating ABCA1 and ABCG1 expression by targeting ATG5

Fengxia Guo, Mei He, Yaonan Li, Kangning Zhu, Bing Hu
Article Number: 314
Published online on: 16 September 2026

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Correction Open Access

[Corrigendum] Bcl11b regulates enamel matrix protein expression and dental epithelial cell differentiation during rat tooth development

Ziyue Li, Guoqing Chen, Yaling Yang, Weihua Guo, Weidong Tian
Article Number: 313
Published online on: 16 September 2026

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Review Open Access

Integrin αVβ3 as a context‑dependent regulator of bone homeostasis: Insights into osteoporosis pathogenesis and therapeutic targeting (Review)

Changshun Chen, Xingxi Hu, Sixing Wei, Yongcheng Deng, Qinggang Zhao, Ge Chen, Zhong Cheng, Jianhua Ji, Jinyi Gu
Article Number: 312
Published online on: 15 September 2026

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Article Open Access

Therapeutic effects of exosome‑based hyperin delivery in a cyclophosphamide‑induced mouse model of diminished ovarian reserve

Yi Ying, Yue Wu, Ji Zhou, Yaming Wang, Hongtao Yin, Gang Lu, Ruolang Pan, Liangzhong Lv
Article Number: 311
Published online on: 15 September 2026

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Review Open Access

Arginine metabolism, polyamine homeostasis and ferroptosis in cancer: Molecular links and therapeutic opportunities (Review)

Xin Dong, Yongkun Hou, Jingjing Shao, Haixia Zhu, Jibin Liu
Article Number: 310
Published online on: 15 September 2026

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Review Open Access

Mitochondria‑associated endoplasmic reticulum membranes in degenerative musculoskeletal disorders: Mechanistic evidence and therapeutic perspectives (Review)

Shilong Meng, Xinlei Fu, Yawei Xu, Zhiliang Peng, Xu Zhang, Yanguang Cao, Binbin Tang, Xiaolin Shi, Kang Liu
Article Number: 309
Published online on: 15 September 2026

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Article Open Access

High‑fat diet exacerbates hepatic and adipose insulin signaling impairment and ovarian lesions in a rat model of letrozole‑induced polycystic ovary syndrome

Sunju So, Sujin Kwon, La Yoon Choi, Dae Yong Kim, Mi Hye Kim
Article Number: 308
Published online on: 15 September 2026

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Retraction Open Access

[Retracted] RNAi‑mediated A disintegrin and metalloproteinase 9 gene silencing inhibits the tumor growth of non‑small lung cancer in vitro and in vivo

Liang Chang, Fangchao Gong, Youbin Cui
Article Number: 307
Published online on: 14 September 2026

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Article Open Access

A four‑gene signature identifies TKI‑induced persister cells and uncovers a ZLN005‑induced pyroptotic vulnerability via the GSDME pathway in EGFR‑mutant lung cancer

Wenwen Chang, Jiaxin Yuan, Huilin Zhang, Ying Yu, Yan Ma, Mingyue Li, Wenjing Li, Hongxia Yan, Chongran Sun, Peng Zhang, Yang Tian, Feng Guo, Pan Li, Yang Sun
Article Number: 306
Published online on: 11 September 2026

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Review Open Access

Research advances in the microbiota‑gut‑brain axis and Parkinson's disease (Review)

Yangping Meng, Qian Liu, Hao Zou, Xingyu Zhu, Xinxin Mi, Sitong Li, Yutian Xia, Yucheng Ma, Qianyu Yang, Jiaxin Peng, Junrui Li, Xingliang Liu, Junli Chen
Article Number: 305
Published online on: 10 September 2026

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Article Open Access

Ameliorative effects of Paulownia tomentosa flower absolute on atopic dermatitis‑related responses in mast cells and keratinocytes and its chemical composition

Da Yeon Yoo, Kyung Jong Won, Do Yoon Kim, Yoon Yi Kim, Ji Hye Bae, Ji Seong Yun, Hwan Myung Lee
Article Number: 304
Published online on: 10 September 2026

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Retraction Open Access

[Retracted] PYGB siRNA inhibits the cell proliferation of human osteosarcoma cell lines

Shuwei Zhang, Yichi Zhou, Yuanyu Zha, Yang Yang, Linlong Wang, Jingfeng Li, Wei Jin
Article Number: 303
Published online on: 10 September 2026

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Article Open Access

KIF4A drives esophageal squamous cell carcinoma via Wnt/β‑catenin signaling and predicts poor prognosis

Jialong Chen, Tong Wang, Da Wang, Weiguo Liu, Chunlai Liu, Yang Yang, Xiangfu Sun, Lei Zhou
Article Number: 302
Published online on: 08 September 2026

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Review Open Access

Research progress of aptamers in the diagnosis and treatment of colorectal cancer (Review)

Yiwen Li, Penghui Yan, Ji Zhang, Binghui Wu, Min Li, Baoliang Bao
Article Number: 301
Published online on: 08 September 2026

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Review Open Access

Role of the circadian rhythm in squamous cell carcinoma: From molecular mechanism to therapy (Review)

Mary-Lyn Eichhorn, Anna M. Dmitrieva, Lydia Meder
Article Number: 300
Published online on: 08 September 2026

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Expression of Concern Open Access

[Expression of Concern] Ganoderma lucidum polysaccharide inhibits prostate cancer cell migration via the protein arginine methyltransferase 6 signaling pathway

Xiaohui Zhao, Dayu Zhou, Yunen Liu, Chun Li, Xiaoguang Zhao, Ying Li, Wei Li
Article Number: 299
Published online on: 07 September 2026

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Review Open Access

Multi‑omics approaches to decipher the molecular mechanisms of exercise‑mediated bone protection: From mechanistic insights to personalized exercise prescription (Review)

Bin Tian, Xuesong Chen, Xin Kang
Article Number: 298
Published online on: 03 September 2026

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Retraction Open Access

[Retracted] MicroRNA‑27a promotes tumorigenesis via targeting AKT in triple negative breast cancer

Jing Wu, Zhihui Sun, Huijie Sun, Yanhua Li
Article Number: 297
Published online on: 03 September 2026

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Journal Cover
December-2026 Volume 34 Issue 6

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Journal Metrics

Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Gut‑kidney axis in chronic kidney disease: Dysbiosis, uremic metabolites and therapeutic opportunities (Review) 

Yinding Wang, Hanyu Zeng, Na Liu, Dong Yang
Article Number: 336
Published online on: 16 October 2026

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Glycyrrhizic acid attenuates corneal inflammation and pathological angiogenesis through FAK/PI3K/AKT signaling

Jinjin Yu, Huiheng Qu, Yinming Fang, Weicheng Xu, Nannan Ding, Jie Ji, Nan Wang, Wei Shi
Article Number: 335
Published online on: 15 October 2026

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Erbin deficiency exacerbates sepsis‑induced liver injury through mitochondrial ROS/NLRP3‑mediated inflammatory responses

Jing Zuo, Xing Wang, Guoqing Jing, Xiaojing Wu, Xuemin Song
Article Number: 334
Published online on: 15 October 2026

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Review Open Access

Gut microbiota in patients receiving dialysis: Mechanisms, complications and the road to personalized microbiome‑based care (Review)

Chenxia Jin, Yanping Wang
Article Number: 333
Published online on: 15 October 2026

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Article Open Access

Epigallocatechin gallate and thermal cycling‑stimulation synergistically promote apoptosis in A549 cells via endoplasmic reticulum stress‑induced calcium ion dysregulation and oxidative stress

Fang-Tzu Hsu, Hsu-Hsiang Liu, Yi Kung, Chieh-Jou Lin, Chih-Yu Chao
Article Number: 332
Published online on: 15 October 2026

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Piezo1 knockdown alleviates high‑altitude cerebral edema by improving brain microvascular endothelial cell tight junctions via blocking the calcium influx‑mediated Calpain‑1 activity

Taijian Cao, Zhicheng Xiang, Yangyang Zhao, Drolma Gomchok, Haifeng Ma, Shiwang Li, Dahai Cao, Chunqing Yang, Qiang Zhang
Article Number: 331
Published online on: 13 October 2026

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Navigating the landscape of targeted therapies for renal cell carcinoma in the era of precision medicine (Review)

Hongguo Cui, Jingheng Song, Peisen Yang, Zhengchao Zhang, Yuanyuan Liu, Gang Zhang, Aimin Tian, Jizhong Che, Yangyang Liu, Hui Sun, Yankai Xu
Article Number: 330
Published online on: 13 October 2026

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ΔNp63α‑mediated regulation of tumor‑associated genes and pathways in hepatocellular carcinoma progression

Xiaowen Lin, Anghui Peng, Min Zhang, Xinyang Yu
Article Number: 329
Published online on: 13 October 2026

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 Leptin promotes obesity‑related osteoarthritis progression via CD44/JAK2/STAT3 axis‑mediated chondrocyte apoptosis

Hao Qiu, Chao Zeng, Cheng Chen, Xin Zhou, Yongjun Zhu, Zhongliang Deng
Article Number: 328
Published online on: 09 October 2026

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Mechanical‑immune feedback regulation in distraction osteogenesis: From mechanotransduction to immune microenvironment remodeling (Review)

Xian Wang, Yuetong Wang, Shixi He, Cheng Ma, Zhengzhong He, Xuanping Huang
Article Number: 327
Published online on: 08 October 2026

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Review Open Access

Research progress in synergistic multimechanism of nanomaterial-mediated neuroinflammatory therapy (Review)

Heng Wang, Pei Yang, Wantao Liu
Article Number: 326
Published online on: 07 October 2026

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Retraction Open Access

[Retracted] (‑)‑Epicatechin protects against myocardial ischemia‑induced cardiac injury via activation of the PTEN/PI3K/AKT pathway

Jia-Wen Li, Xiao-Yun Wang, Xin Zhang, Lei Gao, Li-Feng Wang, Xin-Hua Yin
Article Number: 325
Published online on: 05 October 2026

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Review Open Access

Lactylation and exercise: A molecular link to disease alleviation (Review)

Jian Wang, Lei Wu
Article Number: 324
Published online on: 02 October 2026

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