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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
March-2020 Volume 43 Issue 3

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article

Clinical significance of the molecular heterogeneity of gastrointestinal stromal tumors and related research: A systematic review

Haixiang Ding, Xiuchong Yu, Yu Yu, Xifeng Lao, Chen Hang, Kaijun Gao, Yangtao Jia, Zhilong Yan
Pages: 751-764
Published online on: 17 January 2020

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Article Open Access

Cyclin F is involved in response to cisplatin treatment in melanoma cell lines

Adrian Krajewski, Maciej Gagat, Agnieszka Żuryń, Marta Hałas‑Wiśniewska, Dariusz Grzanka, Alina Grzanka
Pages: 765-772
Published online on: 14 January 2020

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Article Open Access

PI3K/mTORC1/2 inhibitor PQR309 inhibits proliferation and induces apoptosis in human glioblastoma cells

Kun Yang, Xiang‑Jun Tang, Feng‑Fei Xu, Jun‑Hui Liu, Yin‑Qiu Tan, Lun Gao, Qian Sun, Xiang Ding, Bao‑Hui Liu, Qian‑Xue Chen
Pages: 773-782
Published online on: 20 January 2020

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Article Open Access

Silencing of PPM1D inhibits cell proliferation and invasion through the p38 MAPK and p53 signaling pathway in papillary thyroid carcinoma

Zhong‑Wu Lu, Duo Wen, Wen‑Jun Wei, Li‑Tao Han, Jun Xiang, Yu‑Long Wang, Yu Wang, Tian Liao, Qing‑Hai Ji
Pages: 783-794
Published online on: 09 January 2020

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Article Open Access

A signature of tumor immune microenvironment genes associated with the prognosis of non‑small cell lung cancer

Jia Li, Xin Li, Chenyue Zhang, Chenxing Zhang, Haiyong Wang
Pages: 795-806
Published online on: 14 January 2020

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Article Open Access

Cyclovirobuxine D inhibits cell proliferation and migration and induces apoptosis in human glioblastoma multiforme and low‑grade glioma

Lingqi Zhou, Hai Tang, Fang Wang, Shanshan Ou, Tong Wu, Yinchao Fang, Jie Xu, Kaihua Guo
Pages: 807-816
Published online on: 13 January 2020

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Article Open Access

Identification of anaplastic lymphoma kinase fusions in clear cell renal cell carcinoma

Wei Chen, Wei Li, Bing Bai, Huafeng Wei
Pages: 817-826
Published online on: 14 January 2020

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Article Open Access

Curcumin induces re‑expression of BRCA1 and suppression of γ synuclein by modulating DNA promoter methylation in breast cancer cell lines

Nujoud Al‑Yousef, Zakia Shinwari, Bushra Al‑Shahrani, Maram Al‑Showimi, Nisreen Al‑Moghrabi
Pages: 827-838
Published online on: 20 January 2020

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Article Open Access

Inhibitory mechanism of muscone in liver cancer involves the induction of apoptosis and autophagy

Wenchuan Qi, Zhenhua Li, Chunlan Yang, Jiangshan Jiangshan Dai, Qiao Zhang, Di Wang, Chuanfang Wu, Longjiang Xia, Si Xu
Pages: 839-850
Published online on: 29 January 2020

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Article Open Access

An albumin‑binding domain and targeting peptide‑based recombinant protein and its enediyne‑integrated analogue exhibit directional delivery and potent inhibitory activity on pancreatic cancer with K‑ras mutation

Weijin Sheng, Jing Geng, Liang Li, Yue Shang, Min Jiang, Yongsu Zhen
Pages: 851-863
Published online on: 15 January 2020

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Article Open Access

TGM3 functions as a tumor suppressor by repressing epithelial‑to‑mesenchymal transition and the PI3K/AKT signaling pathway in colorectal cancer

Yifei Feng, Dongjian Ji, Yuanjian Huang, Bing Ji, Yue Zhang, Jie Li, Wen Peng, Chuan Zhang, Dongsheng Zhang, Yueming Sun, Ziwei Xu
Pages: 864-876
Published online on: 21 January 2020

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Article Open Access

DNA aneuploidy and tissue architecture in oral potentially malignant disorders with epithelial dysplasia assessed by a 10 locus FISH panel

Zuraiza Mohamad Zaini, Michael Neat, Angela Stokes, Mahvash Tavassoli, Edward W. Odell
Pages: 877-885
Published online on: 13 January 2020

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Article Open Access

Ginsenoside CK induces apoptosis and suppresses proliferation and invasion of human osteosarcoma cells through the PI3K/mTOR/p70S6K1 pathway

Kang Chen, Jianbao Jiao, Jinwei Xue, Taoping Chen, Yu Hou, Yuantao Jiang, Ligang Qian, Yunfei Wang, Zheng Ma, Zhixing Liang, Bo Sun, Qiao Ren
Pages: 886-896
Published online on: 13 January 2020

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Article Open Access

Long non‑coding RNA GAS5 increases the radiosensitivity of A549 cells through interaction with the miR‑21/PTEN/Akt axis

Li Chen, Ping Ren, Yandong Zhang, Baijuan Gong, Dehai Yu, Xiguang Sun
Pages: 897-907
Published online on: 15 January 2020

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Article Open Access

Interleukin 1β/1RA axis in colorectal cancer regulates tumor invasion, proliferation and apoptosis via autophagy

Yusheng Chen, Zhou Yang, Bo Deng, Dejun Wu, Yingjun Quan, Zhijun Min
Pages: 908-918
Published online on: 22 January 2020

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Article Open Access

Knockdown of SLCO4C1 inhibits cell proliferation and metastasis in endometrial cancer through inactivating the PI3K/Akt signaling pathway

Xiang Hu, Tong Han, Yiding Bian, Huan Tong, Xiaoli Wen, Yiran Li, Xiaoping Wan
Pages: 919-929
Published online on: 23 January 2020

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Article Open Access

Linc00261 inhibits metastasis and the WNT signaling pathway of pancreatic cancer by regulating a miR‑552‑5p/FOXO3 axis

Tengxiang Chen, Shan Lei, Zhirui Zeng, Jinjuan Zhang, Yan Xue, Yuanmei Sun, Jinzhi Lan, Su Xu, Dahua Mao, Bing Guo
Pages: 930-942
Published online on: 27 January 2020

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Article

Variant analysis of prostate cancer in Japanese patients and a new attempt to predict related biological pathways

Rika Kasajima, Rui Yamaguchi, Eigo Shimizu, Yoshinori Tamada, Atsushi Niida, George Tremmel, Takeshi Kishida, Ichiro Aoki, Seiya Imoto, Satoru Miyano, Hiroji Uemura, Yohei Miyagi
Pages: 943-952
Published online on: 27 January 2020

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Article Open Access

MicroRNA‑29c‑3p acts as a tumor suppressor gene and inhibits tumor progression in hepatocellular carcinoma by targeting TRIM31

Tao  Lv, Li Jiang, Lingxiang Kong, Jiayin Yang
Pages: 953-964
Published online on: 17 January 2020

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Article Open Access

Downregulation of GPSM2 is associated with primary resistance to paclitaxel in breast cancer

Zhe Zhang, Zhi Li, Mingming Deng, Bofang Liu, Xing Xin, Zhenkun Zhao, Ye Zhang, Qingjie Lv
Pages: 965-974
Published online on: 17 January 2020

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Article

Myoglobin variants are expressed in human glioblastoma cells‑hypoxia effect?

Rana El‑Tohamy, Islam Elkholi, Marwa E. Elsherbiny, Mona Magdy, Olfat Hammam, Joan Allalunis‑Turner, Marwan Emara
Pages: 975-985
Published online on: 23 January 2020

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Article

Treatment with a probiotic combination reduces abdominal adhesion in rats by decreasing intestinal inflammation and restoring microbial composition

Xiaorong Deng, Cihua Zheng, Shuai Wang, Rong Yang, Zhaoxia Liu, Tingtao Chen
Pages: 986-998
Published online on: 14 January 2020

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Article

High PD‑L1 expression drives glycolysis via an Akt/mTOR/HIF‑1α axis in acute myeloid leukemia

Ping Ma, Mengtao Xing, Lijie Han, Silin Gan, Jie Ma, Feifei Wu, Yumin Huang, Yanli Chen, Wenliang Tian, Chao An, Hui Sun, Ling Sun
Pages: 999-1009
Published online on: 23 January 2020

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Article

Suppression of DRP1‑mediated mitophagy increases the apoptosis of hepatocellular carcinoma cells in the setting of chemotherapy

Min Ma, Xia‑Hui Lin, Hua‑Hua Liu, Rui Zhang, Rong‑Xin Chen
Pages: 1010-1018
Published online on: 22 January 2020

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Article

Pioglitazone as a modulator of the chemoresistance of renal cell adenocarcinoma to methotrexate

Iwona Piątkowska‑Chmiel, Monika Gawrońska‑Grzywacz, Dorota Natorska‑Chomicka, Mariola Herbet, Marcin Sysa, Magdalena Iwan, Agnieszka Korga, Jarosław Dudka
Pages: 1019-1030
Published online on: 29 January 2020

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Retraction Open Access

[Retracted] Downregulation of NOB1 suppresses the proliferation and tumor growth of non‑small cell lung cancer in vitro and in vivo

Yang Li, Chengyuan Ma, Ming Qian, Zhongmei Wen, Hongyu Jing, Donghua Qian
Pages: 1031-1031
Published online on: 29 January 2020

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Correction Open Access

[Corrigendum] MicroRNA‑497 inhibits the proliferation, migration and invasion of human bladder transitional cell carcinoma cells by targeting E2F3

Yixiao Zhang, Zhe Zhang, Zhenhua Li, Daxin Gong, Bo Zhan, Xiaojun Man, Chuize Kong
Pages: 1032-1032
Published online on: 14 January 2020

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Journal Cover
February-2026 Volume 55 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

Exploring the role of disulfidptosis‑related signatures in immune microenvironment, prognosis and therapeutic strategies of cholangiocarcinoma

Yue Chen, Jun Wu, Danxia Zhu, Lu Jiang, Jian Wang, Dachuan Zhang, Wenting He
Article Number: 37
Published online on: 02 January 2026

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Correction Open Access

[Corrigendum] Isolinderalactone enhances the inhibition of SOCS3 on STAT3 activity by decreasing miR‑30c in breast cancer

Meng-Chi Yen, Ying-Chu Shih, Ya-Ling Hsu, En-Shyh Lin, Yi-Shiuan Lin, Eing-Mei Tsai, Ya-Wen Ho, Ming-Feng Hou, Po-Lin Kuo
Article Number: 36
Published online on: 22 December 2025

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Article Open Access

Hypoxia‑mediated Krebs von den Lungen‑6 expression in breast cancer: Implications for tumor invasion and metastasis

Taisei Ichihara, Yoshihiro Hayashi, Takuya Sato, Mitsuko Iguchi, Makoto Toi, Hironaga Satake, Ichiro Murakami
Article Number: 35
Published online on: 19 December 2025

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Retraction Open Access

[Retracted] β‑elemene decreases cell invasion by upregulating E‑cadherin expression in MCF‑7 human breast cancer cells

Xian Zhang, Yang Zhang, Yinghua Li
Article Number: 34
Published online on: 18 December 2025

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Review Open Access

Research progress on the regulation of ferroptosis in NPC (Review)

Shuai Bai, Yanjie Guo, Jingling Qiang, Qiangfang Dai, Yanling Yang
Article Number: 33
Published online on: 18 December 2025

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Retraction Open Access

[Retracted] Platelet‑derived growth factor BB mediates the glioma‑induced migration of bone marrow‑derived mesenchymal stem cells by promoting the expression of vascular cell adhesion molecule‑1 through the PI3K, P38 MAPK and NF‑κB pathways

Yi Hu, Peng Cheng, Jiang-Chun Ma, Yi-Xue Xue, Yun-Hui Liu
Article Number: 32
Published online on: 08 December 2025

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Review Open Access

Alternative splicing in cancer drug resistance: Mechanisms and therapeutic prospects (Review)

Wenpu Zhu, Zikun Wu, Chai Luv, Banghe Bao, Weijie Zhao, Guanglong Chen, Hang Yang, Huihan Ai, Faqiang Liu, Zhi Li
Article Number: 31
Published online on: 05 December 2025

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Article Open Access

Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells

Liangliang Jin, Li Wei, Junrui Hua, Rong Zhang, Jiaxin Chen, Jinpeng He, Yanli Yang
Article Number: 30
Published online on: 04 December 2025

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Review

Beyond eradication: Therapeutic reprogramming strategies for cancer normalization (Review)

Aliasgar Shahiwala
Article Number: 29
Published online on: 04 December 2025

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Article Open Access

Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy

Rui Zheng, Yusi Liu, Sen Zhou, Guimei Liu, Xiaobin Liu, Yiyuan Yang, Yufu Zhang
Article Number: 28
Published online on: 04 December 2025

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Retraction Open Access

[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Article Number: 27
Published online on: 04 December 2025

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Article Open Access

Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma

Yuto Kitano, Tomoharu Miyashita, Takeo Shimasaki, Isamu Makino, Yoshio Endo, Yasuhiko Yamamoto, Noriyuki Inaki, Shintaro Yagi
Article Number: 26
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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Journal Cover
March-2026 Volume 55 Issue 3

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

CDK1 depletion suppresses glioma malignancy through cell cycle pathway regulation: Mechanistic insights from functional and molecular profiling

Yu Wang, Huandi Zhou, Xuetao Han, Dongdong Zhang, Liubing Hou, Haonan Li, Tianyi Fan, Sijie Li, Xiaoying Xue
Article Number: 41
Published online on: 12 January 2026

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Retraction Open Access

[Retracted] Downregulated microRNA‑200a promotes EMT and tumor growth through the Wnt/β‑catenin pathway by targeting the E‑cadherin repressors ZEB1/ZEB2 in gastric adenocarcinoma

Ningning Cong, Ping Du, Anling Zhang, Fajuan Shen, Juan Su, Peiyu Pu, Tao Wang, Jie Zjang, Chunsheng Kang, Qingyu Zhang
Article Number: 40
Published online on: 12 January 2026

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Review Open Access

Advances in targeting KRAS mutations: A promising approach for the treatment of non‑small cell lung cancer (Review)

Upesh Sharma, Jincheng Song, Hemraj Kandu, Yue Zhu, Zhaoxia Dai
Article Number: 39
Published online on: 08 January 2026

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Correction Open Access

[Corrigendum] CXCR6 predicts poor prognosis in gastric cancer and promotes tumor metastasis through epithelial-mesenchymal transition

Jie-Jie Jin, Fa-Xiang Dai, Zi-Wen Long, Hong Cai, Xiao-Wen Liu, Ye Zhou, Qi Hong, Qiong-Zhu Dong, Ya-Nong Wang, Hua Huang
Article Number: 38
Published online on: 05 January 2026

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