Journal Articles
Review
Repositioning of drugs using open-access data portal DTome: A test case with probenecid (Review)
Mohammad U. Ahmed, Dylan J. Bennett, Tze-Chen Hsieh, Barbara B. Doonan, Saba Ahmed, Joseph M. Wu
Pages: 3-10 Published online on: 13 November 2015
Review
Characteristics of α-Gal epitope, anti-Gal antibody, α1,3 galactosyltransferase and its clinical exploitation (Review)
Guoli Huai, Ping Qi, Hongji Yang, Yi Wang
Pages: 11-20 Published online on: 30 October 2015
Article
Pharmacological activation of estrogen receptors-α and -β differentially modulates keratinocyte differentiation with functional impact on wound healing
Vlasta Peržeľová, František Sabol, Tomáš Vasilenko, Martin Novotný, Ivan Kováč, Martin Slezák, Ján Ďurkáč, Martin Hollý, Martina Pilátová, Pavol Szabo, Lenka Varinská, Zuzana Čriepoková, Tomáš Kučera, Herbert Kaltner, Sabine André, Hans‑Joachim Gabius, Pavel Mučaji, Karel Smetana, Peter Gál
Pages: 21-28 Published online on: 21 September 2015
Article
Non-thermal dielectric-barrier discharge plasma damages human keratinocytes by inducing oxidative stress
Ki Cheon Kim, Mei Jing Piao, Susara Ruwan Kumara Madduma Hewage, Xia Han, Kyoung Ah Kang, Jin Oh Jo, Young Sun Mok, Jennifer H. Shin, Yeunsoo Park, Suk Jae Yoo, Jin Won Hyun
Pages: 29-38 Published online on: 09 November 2015
Article
Exogenous spermine inhibits the proliferation of human pulmonary artery smooth muscle cells caused by chemically-induced hypoxia via the suppression of the ERK1/2- and PI3K/AKT-associated pathways
Can Wei, Hong-Zhu Li, Yue-Hong Wang, Xue Peng, Hong-Jiang Shao, Hong-Xia Li, Shu-Zhi Bai, Xiao-Xiao Lu, Ling-Yun Wu, Rui Wang, Chang-Qing Xu
Pages: 39-46 Published online on: 11 November 2015
Article
MicroRNA-375 overexpression influences P19 cell proliferation, apoptosis and differentiation through the Notch signaling pathway
Lihua Wang, Guixian Song, Ming Liu, Bin Chen, Yumei Chen, Yahui Shen, Jingai Zhu, Xiaoyu Zhou
Pages: 47-55 Published online on: 02 November 2015
Article
The interactive association between heat shock factor 1 and heat shock proteins in primary myocardial cells subjected to heat stress
Shu Tang, Hongbo Chen, Yanfen Cheng, Mohammad Abdel Nasir, Nicole Kemper, Endong Bao
Pages: 56-62 Published online on: 19 November 2015
Article
Regulation of the osteogenic and adipogenic differentiation of bone marrow-derived stromal cells by extracellular uridine triphosphate: The role of P2Y2 receptor and ERK1/2 signaling
Wenkai Li, Sheng Wei, Chaoxu Liu, Mingyu Song, Hua Wu, Yong Yang
Pages: 63-73 Published online on: 03 November 2015
Article
The activation of p38 MAPK limits the abnormal proliferation of vascular smooth muscle cells induced by high sodium concentrations
Yan Wu, Juan Zhou, Huan Wang, Yue Wu, Qiyue Gao, Lijun Wang, Qiang Zhao, Peining Liu, Shanshan Gao, Wen Wen, Weiping Zhang, Yan Liu, Zuyi Yuan
Pages: 74-82 Published online on: 27 October 2015
Article
Resveratrol alleviates the cytotoxicity induced by the radiocontrast agent, ioxitalamate, by reducing the production of reactive oxygen species in HK-2 human renal proximal tubule epithelial cells in vitro
Yen Ta Huang, Yi Ya Chen, Yu Hsien Lai, Chuan Chu Cheng, Tzu Chun Lin, Ying Shih Su, Chin Hung Liu, Pei Chun Lai
Pages: 83-91 Published online on: 09 November 2015
Article
Anti-wrinkle effects of a tuna heart H2O fraction on Hs27 human fibroblasts
Young-Min Kim, Hee-Jin Jung, Jae-Sue Choi, Taek-Jeong Nam
Pages: 92-98 Published online on: 11 November 2015
Article
TLR4-mediated NF-κB signaling pathway mediates HMGB1-induced pancreatic injury in mice with severe acute pancreatitis
Gang Li, Xuejun Wu, Le Yang, Yuxiang He, Yang Liu, Xing Jin, Hai Yuan
Pages: 99-107 Published online on: 13 November 2015
Article
Suppression of TPA-induced cancer cell invasion by Peucedanum japonicum Thunb. extract through the inhibition of PKCα/NF-κB-dependent MMP-9 expression in MCF-7 cells
Jeong-Mi Kim, Eun-Mi Noh, Ha-Rim Kim, Mi-Seong Kim, Hyun-Kyung Song, Minok Lee, Sei-Hoon Yang, Guem-San Lee, Hyoung-Chul Moon, Kang-Beom Kwon, Young-Rae Lee
Pages: 108-114 Published online on: 19 November 2015
Article
Comparison of molecular profiles of human mesenchymal stem cells derived from bone marrow, umbilical cord blood, placenta and adipose tissue
June Seok Heo, Youjeong Choi, Han-Soo Kim, Hyun Ok Kim
Pages: 115-125 Published online on: 19 November 2015
Article
Orexin A induces autophagy in HCT-116 human colon cancer cells through the ERK signaling pathway
Jing Wen, Yuyan Zhao, Lei Guo
Pages: 126-132 Published online on: 13 November 2015
Article
Adipocyte and leptin accumulation in tumor-induced thymic involution
Alejandro Lamas, Elena Lopez, Roberto Carrio, Diana M. Lopez
Pages: 133-138 Published online on: 27 October 2015
Article
Integrated analyses of a major histocompatibility complex, methylation and transcribed ultra-conserved regions in systemic lupus erythematosus
Hua Lin, Weiguo Sui, Qiupei Tan, Jiejing Chen, Yue Zhang, Minglin Ou, Wen Xue, Fengyan Li, Cuihui Cao, Yufeng Sun, Yong Dai
Pages: 139-148 Published online on: 19 November 2015
Article
An exploration of the antioxidant effects of garlic saponins in mouse-derived C2C12 myoblasts
Ji Sook Kang, Sung Ok Kim, Gi-Young Kim, Hye Jin Hwang, Byung Woo Kim, Young-Chae Chang, Wun-Jae Kim, Cheol Min Kim, Young Hyun Yoo, Yung Hyun Choi
Pages: 149-156 Published online on: 30 October 2015
Article
The novel anti-adipogenic effect and mechanisms of action of SGI-1776, a Pim-specific inhibitor, in 3T3-L1 adipocytes
Yu-Kyoung Park, Victor Sukbong Hong, Tae-Yoon Lee, Jinho Lee, Jong-Soon Choi, Dong-Soon Park, Gi-Young Park, Byeong-Churl Jang
Pages: 157-164 Published online on: 19 November 2015
Article
3,5,4'-Tri-O-acetylresveratrol decreases seawater inhalation-induced acute lung injury by interfering with the NF-κB and i-NOS pathways
Lijie Ma, Xiangjun Chen, Ruixuan Wang, Hongtao Duan, Libin Wang, Li Liang, Yandong Nan, Xueying Liu, Ao Liu, Faguang Jin
Pages: 165-172 Published online on: 09 November 2015
Article
Uncarboxylated osteocalcin inhibits high glucose-induced ROS production and stimulates osteoblastic differentiation by preventing the activation of PI3K/Akt in MC3T3-E1 cells
Jingli Liu, Jianhong Yang
Pages: 173-181 Published online on: 17 November 2015
Article
Sulforaphane exerts anti-inflammatory effects against lipopolysaccharide-induced acute lung injury in mice through the Nrf2/ARE pathway
Tianjie Qi, Fei Xu, Xixin Yan, Shuai Li, Haitao Li
Pages: 182-188 Published online on: 27 October 2015
Article
IOX1, a JMJD2A inhibitor, suppresses the proliferation and migration of vascular smooth muscle cells induced by angiotensin II by regulating the expression of cell cycle-related proteins
Qi Hu, Jing Chen, Jing Zhang, Changwu Xu, Shuo Yang, Hong Jiang
Pages: 189-196 Published online on: 27 October 2015
Article
Enhanced expression of polysialic acid correlates with malignant phenotype in breast cancer cell lines and clinical tissue samples
Xin Wang, Xiang Li, Ying-Nan Zeng, Fa He, Xiao-Min Yang, Feng Guan
Pages: 197-206 Published online on: 27 October 2015
Article
Osthole ameliorates acute myocardial infarction in rats by decreasing the expression of inflammatory-related cytokines, diminishing MMP-2 expression and activating p-ERK
Juan Duan, Yu Yang, Hong Liu, Peng-Cheng Dou, Sheng-Yu Tan
Pages: 207-216 Published online on: 04 November 2015
Article
Anti-allergic and anti-inflammatory effects of aqueous extract of Pogostemon cablin
Seok Cheol Yoon, In-Gyu Je, Xun Cui, Hae Ran Park, Dongwoo Khang, Jeong-Suk Park, Sang-Hyun Kim, Tae-Yong Shin
Pages: 217-224 Published online on: 03 November 2015
Article
Crocin protects retinal ganglion cells against H2O2-induced damage through the mitochondrial pathway and activation of NF-κB
Bochang Lv, Tao Chen, Zhiguo Xu, Fuquan Huo, Yanyan Wei, Xinguang Yang
Pages: 225-232 Published online on: 23 November 2015
Article
Gain-of-function p53 mutant with 21-bp deletion confers susceptibility to multidrug resistance in MCF-7 cells
Shang-Hsun Tsou, Ming-Hung Hou, Lih-Ching Hsu, Tzer-Ming Chen, Yen-Hui Chen
Pages: 233-242 Published online on: 11 November 2015
Article
Anti-allergic effects of a nonameric peptide isolated from the intestine gastrointestinal digests of abalone (Haliotis discus hannai) in activated HMC-1 human mast cells
Seok-Chun Ko, Dae-Sung Lee, Won Sun Park, Jong Su Yoo, Mi-Jin Yim, Zhong-Ji Qian, Chang-Min Lee, Junghwan Oh, Won-Kyo Jung, Il-Whan Choi
Pages: 243-250 Published online on: 27 November 2015
Article
RACK1 affects glioma cell growth and differentiation through the CNTN2-mediated RTK/Ras/MAPK pathway
Yu Yan, Yugang Jiang
Pages: 251-257 Published online on: 30 November 2015
Article
