Journal Articles
Review
Genome editing: A perspective on the application of CRISPR/Cas9 to study human diseases (Review)
Diana Raquel Rodríguez‑Rodríguez, Ramiro Ramírez‑Solís, Mario Alberto Garza‑Elizondo, María De Lourdes Garza‑Rodríguez, Hugo Alberto Barrera‑Saldaña
Pages: 1559-1574 Published online on: 26 February 2019
Article
Imbalance of angiotensin-converting enzymes affects myocardial apoptosis during cardiac arrest induced by acute pulmonary embolism in a porcine model
Hong‑Li Xiao, Lian‑Xing Zhao, Jun Yang, Nan Tong, Le An, Qi‑Tong Liu, Miao‑Rong Xie, Chun-Sheng Li
Pages: 1575-1584 Published online on: 26 February 2019
Article
MicroRNA‑199a‑5p functions as a tumor suppressor in oral squamous cell carcinoma via targeting the IKKβ/NF‑κB signaling pathway
Dongyi Wei, Baohong Shen, Weixin Wang, Yanjun Zhou, Xiaodong Yang, Guangjian Lu, Jianbin Yang, Yuebao Shao
Pages: 1585-1596 Published online on: 29 January 2019
Article
Nucleolin promotes Ang II‑induced phenotypic transformation of vascular smooth muscle cells via interaction with tropoelastin mRNA
Li Fang, Peng‑Fei Zhang, Kang‑Kai Wang, Zhi‑Lin Xiao, Mei Yang, Zai‑Xin Yu
Pages: 1597-1610 Published online on: 04 February 2019
Article
Metformin prevents nephrolithiasis formation by inhibiting the expression of OPN and MCP-1 in vitro and in vivo
Xiong Yang, Tong Yang, Jie Li, Rui Yang, Shiyong Qi, Yang Zhao, Liang Li, Jingjin Li, Xuening Zhang, Kuo Yang, Yong Xu, Chunyu Liu
Pages: 1611-1622 Published online on: 30 January 2019
Article
miR-135 regulated breast cancer proliferation and epithelial-mesenchymal transition acts by the Wnt/β-catenin signaling pathway Corrigendum in /10.3892/ijmm.2022.5161
Daqiong Jiang, Bo Zhou, Yan Xiong, Hongbing Cai
Pages: 1623-1634 Published online on: 29 January 2019
Article
Enhanced antiproliferative effect of resveratrol in head and neck squamous cell carcinoma using GE11 peptide conjugated liposome
Tingting Zheng, Huanhuan Feng, Li Liu, Jiao Peng, Haitao Xiao, Tao Yu, Ziqian Zhou, Ying Li, Yuseng Zhang, Xiaohe Bai, Simeng Zhao, Yu Shi, Yun Chen
Pages: 1635-1642 Published online on: 13 February 2019
Article
Bioinformatic analysis of next‑generation sequencing data to identify dysregulated genes in fibroblasts of idiopathic pulmonary fibrosis
Chau‑Chyun Sheu, Wei‑An Chang, Ming‑Ju Tsai, Ssu‑Hui Liao, Inn‑Wen Chong, Po‑Lin Kuo
Pages: 1643-1656 Published online on: 31 January 2019
Article
Interleukin‑22 regulates the homeostasis of the intestinal epithelium during inflammation
Xinyan Zhang, Shijie Liu, Yueqian Wang, Huiqiong Hu, Liang Li, Yibin Wu, Duo Cao, Yuankun Cai, Jiqin Zhang, Xueli Zhang
Pages: 1657-1668 Published online on: 07 February 2019
Article
Magnolol prevents ovariectomy‑induced bone loss by suppressing osteoclastogenesis via inhibition of the nuclear factor‑κB and mitogen‑activated protein kinase pathways
Wen‑Yong Fei, Qiang Huo, Pei‑Qing Zhao, Long‑Juan Qin, Tao Li
Pages: 1669-1678 Published online on: 18 February 2019
Article
Berberine prevents human nucleus pulposus cells from IL‑1β‑induced extracellular matrix degradation and apoptosis by inhibiting the NF‑κB pathway
Lin Lu, Jialang Hu, Qipeng Wu, Ying An, Wei Cui, Junwen Wang, Zhewei Ye
Pages: 1679-1686 Published online on: 21 February 2019
Article
Co‑expression of Lewis y antigen and CD147 in epithelial ovarian cancer is correlated with malignant progression and poor prognosis
Juanjuan Liu, Qi Liu, Yanyan Wang, Miao Liu, Yue Qi, Jian Gao, Bei Lin
Pages: 1687-1698 Published online on: 20 February 2019
Article
Circular RNA expression profiles in neonatal rats following hypoxic-ischemic brain damage
Li Jiang, Huijuan Li, Zhongmin Fan, Ruibin Zhao, Zhengkun Xia
Pages: 1699-1708 Published online on: 26 February 2019
Article
Identification of survival‑associated key genes and long non‑coding RNAs in glioblastoma multiforme by weighted gene co‑expression network analysis
Xin Chen, Changcun Pan, Cheng Xu, Yu Sun, Yibo Geng, Lu Kong, Xiong Xiao, Zitong Zhao, Wei Zhou, Lijie Huang, Yongmei Song, Liwei Zhang
Pages: 1709-1722 Published online on: 19 February 2019
Article
Identification of biomarkers associated with the recurrence of osteosarcoma using ceRNA regulatory network analysis
Shanyong Zhang, Lei Ding, Xin Li, Hongwu Fan
Pages: 1723-1733 Published online on: 25 February 2019
Article
miR-183 modulated cell proliferation and apoptosis in ovarian cancer through the TGF-β/Smad4 signaling pathway
Junhui Zhou, Caixia Zhang, Bo Zhou, Daqiong Jiang
Pages: 1734-1746 Published online on: 29 January 2019
Article
Nrdp1 is involved in hippocampus apoptosis in cardiopulmonary bypass-induced cognitive dysfunction via the regulation of ErbB3 protein levels
Jie Zheng, Su Min, Bin Hu, Qin Liu, Yunqiang Wan
Pages: 1747-1757 Published online on: 28 January 2019
Article
SIRT1 inhibits apoptosis in in vivo and in vitro models of spinal cord injury via microRNA-494
Xiaobing Yu, Shuo Zhang, Dewei Zhao, Xiuzhi Zhang, Chongjun Xia, Tienan Wang, Meng Zhang, Tao Liu, Wei Huang, Baolin Wu
Pages: 1758-1768 Published online on: 22 February 2019
Article
Salidroside protects PC-12 cells against amyloid β-induced apoptosis by activation of the ERK1/2 and AKT signaling pathways
Zheng‑Luan Liao, Heng Su, Yun‑Fei Tan, Ya‑Ju Qiu, Jun‑Peng Zhu, Yan Chen, Si‑Si Lin, Ming‑Hao Wu, Yan‑Ping Mao, Jiao‑Jiao Hu, En‑Yan Yu
Pages: 1769-1777 Published online on: 01 February 2019
Article
Inhibition of acid‑sensing ion channel 1a attenuates acid‑induced activation of autophagy via a calcium signaling pathway in articular chondrocytes
Wen‑Fan Gao, Ya‑Yun Xu, Jin‑Fang Ge, Fei‑Hu Chen
Pages: 1778-1788 Published online on: 31 January 2019
Article
All‑trans retinoic acid alters the expression of the tight junction proteins Claudin‑1 and ‑4 and epidermal barrier function‑associated genes in the epidermis
Jing Li, Qianying Li, Songmei Geng
Pages: 1789-1805 Published online on: 15 February 2019
Article
MicroRNA-30e regulates TGF-β-mediated NADPH oxidase 4-dependent oxidative stress by Snai1 in atherosclerosis
Ye Cheng, Meili Zhou, Wenjun Zhou
Pages: 1806-1816 Published online on: 20 February 2019
Article
Effects of miR‑106b‑3p on cell proliferation and epithelial‑mesenchymal transition, and targeting of ZNRF3 in esophageal squamous cell carcinoma
Guanen Qiao, Chenguang Dai, Yang He, Junjie Shi, Chunfang Xu
Pages: 1817-1829 Published online on: 25 February 2019
Article
Physalis peruviana L. inhibits ovalbumin‑induced airway inflammation by attenuating the activation of NF‑κB and inflammatory molecules
Hyun Ah Park, Ok‑Kyoung Kwon, Hyung Won Ryu, Jae‑Hong Min, Min‑Woo Park, Mi‑Hyeong Park, Jin‑Hyub Paik, Sangho Choi, Imam Paryanto, Prasetyawan Yuniato, Sei‑Ryang Oh, Kyung‑Seop Ahn, Jae‑Won Lee
Pages: 1830-1838 Published online on: 26 February 2019
Article
NR2F2 loss‑of‑function mutation is responsible for congenital bicuspid aortic valve
Juan Wang, Pradhan Abhinav, Ying‑Jia Xu, Ruo‑Gu Li, Min Zhang, Xing‑Biao Qiu, Ruo‑Min Di, Qi Qiao, Xiu‑Mei Li, Ri‑Tai Huang, Song Xue, Yi‑Qing Yang
Pages: 1839-1846 Published online on: 31 January 2019
Article
Tanshinone IIA inhibits lipopolysaccharide‑induced inflammatory responses through the TLR4/TAK1/NF‑κB signaling pathway in vascular smooth muscle cells
Zhe Meng, Chun‑Ying Si, Shuai Teng, Xin‑Hui Yu, Hai‑Yu Li
Pages: 1847-1858 Published online on: 18 February 2019
Article
Anti‑inflammatory effects of 6‑formyl umbelliferone via the NF‑κB and ERK/MAPK pathway on LPS‑stimulated RAW 264.7 cells
Sang‑Bo Kim, Min‑Jae Kang, Chang‑Won Kang, Nan‑Hee Kim, Hyung Wook Choi, Hyun Ah Jung, Jae Sue Choi, Gun‑Do Kim
Pages: 1859-1865 Published online on: 25 January 2019
Article
Beclin1 inhibition enhances paclitaxel‑mediated cytotoxicity in breast cancer in vitro and in vivo
Cheng‑Lin Wu, Jian‑Fei Liu, Yan Liu, Yu‑Xiao Wang, Kai‑Fei Fu, Xiao‑Jie Yu, Qian Pu, Xiu‑Xiu Chen, Li‑Jun Zhou
Pages: 1866-1878 Published online on: 01 February 2019
Article
Neuroprotective effects of curcumin against rats with focal cerebral ischemia-reperfusion injury
Lu Xu, Ling Ding, Yuanqi Su, Ruyue Shao, Jie Liu, Yan Huang
Pages: 1879-1887 Published online on: 11 February 2019
Article
Effects of HGF and KGF gene silencing on vascular endothelial growth factor and its receptors in rat ultraviolet radiation‑induced corneal neovascularization
Min He, Tao Han, Yan Wang, Yao‑Hong Wu, Wei‑Shan Qin, Ling‑Zhen Du, Chang‑Qing Zhao
Pages: 1888-1899 Published online on: 27 February 2019
Article
Effect of amlodipine besylate combined with acupoint application of traditional Chinese medicine nursing on the treatment of renal failure and hypertension by the PI3K/AKT pathway
Liping Feng, Jiahang Su, Rongxiang Chi, Qiao Zhu, Shuguang Lv, Wenjing Liang
Pages: 1900-1910 Published online on: 20 February 2019
Article
Y-27632, a Rho-kinase inhibitor, attenuates myocardial ischemia-reperfusion injury in rats
Li‑Ya Dong, Xiao‑Xiao Qiu, Yu Zhuang, Song Xue
Pages: 1911-1919 Published online on: 14 February 2019
Correction
[Corrigendum] Bradykinin receptors and EphB2/EphrinB2 pathway in response to high glucose‑induced osteoblast dysfunction and hyperglycemia‑induced bone deterioration in mice
Min Wu, Wenting Ai, Lin Chen, Sihai Zhao, Enqi Liu
Pages: 1920-1920 Published online on: 05 February 2019
Correction
