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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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International Journal of Molecular Medicine

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
November-2019 Volume 44 Issue 5

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review

The prospect of discovering new biomarkers for ovarian cancer based on current knowledge of susceptibility loci and genetic variation (Review)

Mikael Kronborg Christophersen, Claus Høgdall, Estrid Høgdall
Pages: 1599-1608
Published online on: 26 September 2019

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Article Open Access

Decreased collagen type III synthesis in skin fibroblasts is associated with parastomal hernia following colostomy

Fenglin Zhao, Fuqiang Chen, Xin Yuan, Yiting Liu, Jie Chen
Pages: 1609-1618
Published online on: 02 September 2019

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Article Open Access

MicroRNA‑379‑5p suppresses renal fibrosis by regulating the LIN28/let‑7 axis in diabetic nephropathy

Nan Li, Li‑Juan Wang, Wei‑Long Xu, Su Liu , Jiang‑Yi Yu
Pages: 1619-1628
Published online on: 30 August 2019

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Article Open Access

Conditioned medium derived from human amniotic stem cells delays H2O2‑induced premature senescence in human dermal fibroblasts

Changwei Pan, Hongxin Lang, Tao Zhang, Rui Wang, Xuewen Lin, Ping Shi, Feng Zhao, Xining Pang
Pages: 1629-1640
Published online on: 20 September 2019

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Article Open Access

Anti‑photoaging and anti‑oxidative activities of natural killer cell conditioned medium following UV‑B irradiation of human dermal fibroblasts and a reconstructed skin model

Sung‑Eun Lee, Tae‑Rin Kwon, Jong Hwan Kim, Byung‑Chul Lee, Chang Taek Oh, Minju Im, Yu Kyeong Hwang, Sang Hoon Paik, Seungryel Han, Jeom‑Yong Kim, Beom Joon Kim
Pages: 1641-1652
Published online on: 20 August 2019

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Article Open Access

A simplified 3D liver microsphere tissue culture model for hepatic cell signaling and drug-induced hepatotoxicity studies Corrigendum in /10.3892/ijmm.2023.5234

Ying Zhu, Qiong Shi, Qi Peng, Yue Gao, Ting Yang, Yu Cheng, Hao Wang, Yetao Luo, Ailong Huang, Tong‑Chuan He, Jiaming Fan
Pages: 1653-1666
Published online on: 21 August 2019

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Article Open Access

Knockdown of KLK12 inhibits viability and induces apoptosis in human colorectal cancer HT-29 cell line

Qianyuan Li, Xiukou Zhou, Zhengyu Fang, Huamiao Zhou
Pages: 1667-1676
Published online on: 30 August 2019

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Article Open Access

Incremental load training improves renal fibrosis by regulating the TGF‑β1/TAK1/MKK3/p38MAPK signaling pathway and inducing the activation of autophagy in aged mice Corrigendum in /10.3892/ijmm.2023.5274

Chuncha Bao, Zhong Yang, Qiyan Cai, Qian Li, Hongli Li, Bin Shu
Pages: 1677-1686
Published online on: 17 September 2019

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Article Open Access

Piperlongumine induces autophagy in biliary cancer cells via reactive oxygen species-activated Erk signaling pathway

San‑Yuan Chen, Hsin‑Yi Huang, Han‑Pei Lin, Chiung‑Yao Fang
Pages: 1687-1696
Published online on: 23 August 2019

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Article Open Access

IL‑21/IL‑21R inhibit tumor growth and invasion in non‑small cell lung cancer cells via suppressing Wnt/β‑catenin signaling and PD‑L1 expression

Dan Xue, Ping Yang, Qiongying Wei, Xiaoping Li, Lan Lin, Tingyan Lin
Pages: 1697-1706
Published online on: 26 September 2019

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Article Open Access

Overexpressed CD39 mitigates sepsis‑induced kidney epithelial cell injury via suppressing the activation of NLR family pyrin domain containing 3

Meixia Yang, Linxin Lu, Zhiqin Kang, Tianlong Ma, Yu Wang
Pages: 1707-1718
Published online on: 23 September 2019

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Article Open Access

Comprehensive circular RNA profiling reveals the regulatory role of the hsa_circ_0137606/miR‑1231 pathway in bladder cancer progression

Weijian Li, Youjian Li, Zhongxu Sun, Jun Zhou, Yuepeng Cao, Wenliang Ma, Kaipeng Xie, Xiang Yan
Pages: 1719-1728
Published online on: 17 September 2019

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Article Open Access

miR‑134‑5p/Foxp2/Syn1 is involved in cognitive impairment in an early vascular dementia rat model

Xin Liu, Ruilin Zhang, Zimei Wu, Wenwen Si, Zhenxing Ren, Saixia Zhang, Jianhong Zhou, Dongfeng Chen
Pages: 1729-1740
Published online on: 05 September 2019

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Article Open Access

Polyphenol mixture of a native Korean variety of Artemisia argyi H. (Seomae mugwort) and its anti‑inflammatory effects

Seong Min Kim, Soo Jung Lee, Venu Venkatarame Gowda Saralamma, Sang Eun Ha, Preethi Vetrivel, Kebede Taye Desta, Jin Young Choi, Won Sup Lee, Sung Chul Shin, Gon‑Sup Kim
Pages: 1741-1752
Published online on: 09 September 2019

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Article Open Access

Screening and identification of biomarkers for systemic sclerosis via microarray technology

Chen Xu, Ling‑Bing Meng, Yu‑Chen Duan, Yong‑Jing Cheng, Chun‑Mei Zhang, Xing Zhou, Ci‑Bo Huang
Pages: 1753-1770
Published online on: 05 September 2019

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Article Open Access

Fish oils protects against cecal ligation and puncture‑induced septic acute kidney injury via the regulation of inflammation, oxidative stress and apoptosis

Zhaoheng Lin, Jing Jin, Xiyun Shan
Pages: 1771-1780
Published online on: 11 September 2019

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Article Open Access

Connexin 43‑autophagy loop in the podocyte injury of diabetic nephropathy

Jialing Ji, Yajie Zhao, Chen Na, Min Yang, Xianyi Zhu, Huimin Shi, Weihua Gan, Aiqing Zhang
Pages: 1781-1788
Published online on: 10 September 2019

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Article Open Access

CUDC‑907 reverses pathological phenotype of keloid fibroblasts in vitro and in vivo via dual inhibition of PI3K/Akt/mTOR signaling and HDAC2

Tian Tu, Jia Huang, Miaomiao Lin, Zhen Gao, Xiaoli Wu, Wenjie Zhang, Guangdong Zhou, Wenbo Wang, Wei Liu
Pages: 1789-1800
Published online on: 23 September 2019

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Article Open Access

Improved HCN channels in pyramidal neurons and their new expression levels in pericytes and astrocytes in the gerbil hippocampal CA1 subfield following transient ischemia

Joon Ha Park, Dae Won Kim, Tae‑Kyeong Lee, Cheol Woo Park, Young Eun Park, Ji Hyeon Ahn, Hyang‑Ah Lee, Moo‑Ho Won, Choong‑Hyun Lee
Pages: 1801-1810
Published online on: 26 September 2019

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Article Open Access

Overexpression of miR‑200a‑3p promoted inflammation in sepsis‑induced brain injury through ROS‑induced NLRP3

Jianhua Yu, Jinlong Chen, Hualing Yang, Sifang Chen, Zhanxiang Wang
Pages: 1811-1823
Published online on: 30 August 2019

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Article Open Access

miR-217 inhibits the migration and invasion of HeLa cells through modulating MAPK1 Retraction in /10.3892/ijmm.2025.5525

Lihong Zhu, Shumei Yang, Jianfeng Wang
Pages: 1824-1832
Published online on: 02 September 2019

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Article Open Access

MicroRNA-939-5p directly targets IGF-1R to inhibit the aggressive phenotypes of osteosarcoma through deactivating the PI3K/Akt pathway Retraction in /10.3892/ijmm.2022.5181

Xiwu Zhao, Jian Li, Dapeng Yu
Pages: 1833-1843
Published online on: 05 September 2019

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Article Open Access

Comprehensive analysis of long non‑coding RNA‑messenger RNA‑microRNA co‑expression network identifies cell cycle‑related lncRNA in hepatocellular carcinoma

Hai‑Rong Zhu, Xiang‑Nan Yu, Guang‑Cong Zhang, Xuan Shi, Enkhnaran Bilegsaikhan, Hong‑Ying Guo, Li‑Li Liu, Yu Cai, Guang‑Qi Song, Tao‑Tao Liu, Ling Dong, Harry L.A. Janssen, Shu‑Qiang Weng, Jian Wu, Xi‑Zhong Shen, Ji‑Min Zhu
Pages: 1844-1854
Published online on: 23 August 2019

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Article Open Access

Piperlongumine reduces ovalbumin‑induced asthma and airway inflammation by regulating nuclear factor‑κB activation

Chun Lu, Bing Zhang, Tingting Xu, Wenxin Zhang, Bin Bai, Zhongxiang Xiao, Liqin Wu, Guang Liang, Yali Zhang, Yuanrong Dai
Pages: 1855-1865
Published online on: 21 August 2019

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Article Open Access

Kappa opioid receptor agonists improve postoperative cognitive dysfunction in rats via the JAK2/STAT3 signaling pathway

Xi Li, Yingjie Sun, Qiang Jin, Dandan Song, Yugang Diao
Pages: 1866-1876
Published online on: 13 September 2019

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Article Open Access

Quantitative proteomics reveal the alterations in the spinal cord after myocardial ischemia‑reperfusion injury in rats

Shun‑Yuan Li, Zhi‑Xiao Li, Zhi‑Gang He, Qian Wang, Yu‑Juan Li, Qing Yang, Duo‑Zhi Wu, Hao‑Long Zeng, Hong‑Bing Xiang
Pages: 1877-1887
Published online on: 17 September 2019

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Article Open Access

Identification of immunodominant IgE epitopes of the major house dust mite allergen Der f 24

Ze‑Lang Cai, Zhen Zhang, Wen‑Li Luo, Yi‑Bo Hou, Yong‑Shen He, Jia‑Jie Chen, Kunmei Ji
Pages: 1888-1898
Published online on: 18 September 2019

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Article Open Access

Ubiquitin‑proteasomes are the dominant mediators of the regulatory effect of microRNA‑1 on cardiac remodeling after myocardial infarction

Liping Wei, Yufan Zhang, Xin Qi, Xuseng Sun, Yuanyang Li, Yue Xu
Pages: 1899-1907
Published online on: 04 September 2019

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Article Open Access

Fatty liver and alteration of the gut microbiome induced by diallyl disulfide

Yanhong Yang, Fei Yang, Miaoling Huang, Huijuan Wu, Changyuan Yang, Xinyue Zhang, Lanxiang Yang, Guibin Chen, Shuqi Li, Qianyu Wang, Shaomin Liu, Yanyan Liu, Yuting Lei, Zili Lei, Jiao Guo
Pages: 1908-1920
Published online on: 24 September 2019

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Article Open Access

Role of IGFBP1 in the senescence of vascular endothelial cells and severity of aging‑related coronary atherosclerosis

Xiaojing Wu, Wei Zheng, Peng Jin, Junhao Hu, Qi Zhou
Pages: 1921-1931
Published online on: 12 September 2019

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Article Open Access

Isosteviol prevents the development of isoprenaline‑induced myocardial hypertrophy

Yaoxu Chen, Huimin Beng, Hao Su, Fuping Han, Zhuo Fan, Nanying Lv, Aleksandar Jovanović, Wen Tan
Pages: 1932-1942
Published online on: 17 September 2019

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Article Open Access

S‑allyl‑cysteine sulfoxide (alliin) alleviates myocardial infarction by modulating cardiomyocyte necroptosis and autophagy

Li‑Jun Yue, Xi‑Yu Zhu, Rui‑Sha Li, Hui‑Jing Chang, Bing Gong, Chong‑Chong Tian, Chang Liu, Yun‑Xing Xue, Qing Zhou, Tian‑Shu Xu, Dong‑Jin Wang
Pages: 1943-1951
Published online on: 26 September 2019

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Article Open Access

Metabolomic profiling identifies novel biomarkers and mechanisms in human bladder cancer treated with submucosal injection of gemcitabine

Chao Yang, Xian Sun, Hengbing Wang, Ting Lu, Keqing Wu, Yusheng Guan, Jing Tang, Jian Liang, Rongli Sun, Zhongying Guo, Sinian Zheng, Xiaoli Wu, Hesong Jiang, Xi Jiang, Bing Zhong, Xiaobing Niu, Suan Sun, Xinru Wang, Minjian Chen, Guangbo Fu
Pages: 1952-1962
Published online on: 23 September 2019

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Article

Activation of RXR by bexarotene inhibits inflammatory conditions in human rheumatoid arthritis fibroblast‑like synoviocytes

Yu Li, Qunzhi Xing, Yuanzhang Wei, Lei Zhao, Pei Zhang, Xuechang Han, Jing Wang
Pages: 1963-1970
Published online on: 10 September 2019

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Article

SKA1 overexpression is associated with the prognosis of esophageal squamous cell carcinoma and regulates cell proliferation and migration

Dongxin Hu, Zhen Li, Xiao Li, Honghao Fu, Mingyan Zhang
Pages: 1971-1978
Published online on: 17 September 2019

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Article

Indole‑6‑carboxaldehyde isolated from Sargassum thunbergii inhibits the expression and secretion of matrix metalloproteinase‑9

Tae‑Hee Kim, Soo‑Jin Heo, Seok‑Chun Ko, Won Sun Park, Il‑Whan Choi, Myunggi Yi, Won‑Kyo Jung
Pages: 1979-1987
Published online on: 20 August 2019

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Correction Open Access

[Corrigendum] c‑Myc regulates the CDK1/cyclin B1 dependent‑G2/M cell cycle progression by histone H4 acetylation in Raji cells

Yan Yang, Kai Xue, Zhi Li, Wei Zheng, Weijie Dong, Jiazhe Song, Shijie Sun, Tonghui Ma, Wenzhe Li
Pages: 1988-1988
Published online on: 20 August 2019

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Journal Cover
February-2026 Volume 57 Issue 2

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

miR‑205: A dual regulator of angiogenesis in health and disease (Review)

Maria Oltra, Miriam Martínez‑Santos, Maria Ybarra, Maria Pires, Chiara Ceresoni, Clara Gomis‑Coloma, Cristina Medina‑Trillo, Javier Sancho, Jorge Barcia
Article Number: 51
Published online on: 29 December 2025

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Review Open Access

Astragaloside IV: A multipotent phytochemical for treating fibrotic diseases (Review)

Mingyu Wu, Ke Li, Jiabin Wu, Qiuyu Zhang, Xiaotong Ma, Wei Dai, Haoyang Gao, Xianyi Ding, Wenhong Wang, Weihua Xiao
Article Number: 50
Published online on: 24 December 2025

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Review Open Access

Activating transcription factors: Orchestrators of macrophage biology in pathological settings (Review)

Yue-Chen Liu, Jia-Wei Zhao, Xiong-Tao Yue, Qi-Jie Chen, Shan-Jie Rong, Shi-Wei Liu, Fei Sun, Chun-Liang Yang, Cong-Yi Wang
Article Number: 49
Published online on: 24 December 2025

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Review Open Access

Role of SIRT3 in digestive system diseases and therapeutic prospects (Review)

Jiajia Li, Qian Liu, Shun Yao, Xin Li, Li Zhang, Yongfeng Wang, Guorong Wen, Jiaxing An, Hai Jin, Biguang Tuo
Article Number: 48
Published online on: 22 December 2025

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Article Open Access

Recombinant ADAMTS‑1 promotes muscle regeneration accompanied by downregulation of Notch signaling

Jin-Hwa Kim, Sang-Hyup Lee, Sang-Yoon Kim, Jeong-Won Kim, Ji-Soo Jeong, Eun-Hye Chung, Su-Ha Lee, Chang-Yeop Kim, Bong-Keun Choi, Je-Won Ko, Tae-Won Kim
Article Number: 47
Published online on: 22 December 2025

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Review Open Access

A comprehensive review on pain: Model, target, therapy, and prospect (Review)

Chenyu Chang, Xutao Wu, Kejia Liu, Lei Wang, Mozili Adu, Qingyuan Lin, Huilian Huang, Qinge Ma, Rongrui Wei, Xiaoyun Wang, Wenmin Liu
Article Number: 46
Published online on: 17 December 2025

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Retraction Open Access

[Retracted] Curculigoside attenuates myocardial ischemia‑reperfusion injury by inhibiting the opening of the mitochondrial permeability transition pore

Yanbing Zhao, Yuxuan Guo, Yuqiong Chen, Shuang Liu, Nan Wu, Dalin Jia
Article Number: 45
Published online on: 15 December 2025

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Review Open Access

Nanomaterials and exercise interventions: A synergistic approach for atherosclerosis therapy (Review)

Quanquan Zhou, Ge‑Lin Zhang, Weitong Sun, Jiayi Cai, Li-Hua Yu
Article Number: 44
Published online on: 10 December 2025

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Article Open Access

Selective autophagic degradation of glycolytic activator PFKFB3 contributes to maintaining intestinal epithelial barrier in inflammatory bowel disease

Yiyang Pan, Feng Yang, Liucan Wang, Tianshu Yang, Guangsheng Du, Cong Xu, Hua Yang, Min Yu, Weidong Xiao
Article Number: 43
Published online on: 10 December 2025

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Review Open Access

Lactylation‑mediated ferroptosis: A novel mechanism and therapeutic prospects in human diseases (Review)

Zhengjun Lin, Yugang Zou, Songzhu Zou, Kunming Wen
Article Number: 42
Published online on: 08 December 2025

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Review Open Access

Dual role of lactate in ferroptosis: Mechanisms, pathophysiology and therapeutic opportunities (Review)

Qian Yu, Yu Kuang, Jie He, Li Yang, Xinjie Li, Hao Yu
Article Number: 41
Published online on: 08 December 2025

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Retraction Open Access

[Retracted] MicroRNA‑493‑5p promotes apoptosis and suppresses proliferation and invasion in liver cancer cells by targeting VAMP2

Guannan Wang, Xiaosan Fang, Meng Han, Xiaoming Wang, Qiang Huang
Article Number: 40
Published online on: 08 December 2025

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Article Open Access

FGF4 alleviates the lung cell damage caused by high glucose via AMPK‑PGC‑1 signaling axis in vitro and in vivo

Qiujuan Fu, Yongfang Ou, Qin Wu, Jue Gong, Feixia Li, Tuxing Wang, Zhitai Lin, Kejie Huang, Jianlong Xie
Article Number: 39
Published online on: 05 December 2025

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Article Open Access

STOML2 interacts with PHB to activate the MEK/ERK signaling pathway and mediates autophagy‑related proteins in the progression of hepatocellular carcinoma

Haoyang Hu, Haozhe Zhang, Shuai Han, Jianli Chen, Ying Xie
Article Number: 38
Published online on: 04 December 2025

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Article Open Access

HMGB1 mediates low-dose ionizing radiation-induced Wnt/β-catenin activation in SRA01/04 cells: Mechanistic clues to early cataractogenesis

Ping Wang, Chunnan Piao, Dong Yan, Yingxue He, Yaru Li, Li Fan, Mei Tian
Article Number: 37
Published online on: 04 December 2025

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Article Open Access

FBXO22 promotes hepatocellular carcinoma progression via paracrine myo‑inositol‑induced M2‑type polarization of macrophages

Liangliang Bai, Jing Xiong, Sihai Chen, Jiahao Hu, Meixia Zhang, Bimin Li, Jing Hu, Mingyan He
Article Number: 36
Published online on: 02 December 2025

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Review Open Access

Branched‑chain amino acid metabolism and bone metabolism: Implications for osteoporosis pathogenesis and therapeutic strategies (Review)

Qi Xiao, Haimin Zeng, Ruhui Yang, Yuxin Zhan, Fangzhen Lin, Bofan Chen, Xiang Chen
Article Number: 35
Published online on: 02 December 2025

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Review Open Access

Mitochondria-associated endoplasmic reticulum membranes: Emerging regulators of cardiac microvascular ischemia/reperfusion injury (Review)

Yan Wang, Baowei Feng, Yanting Wu, Zongle Sun, Hao Yuan, Wei Chen, Chang Zhao, Zhi Liu
Article Number: 34
Published online on: 02 December 2025

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Review Open Access

Role of matrix metalloproteinases in the invasion of glioblastoma and drug interventions (Review)

Bohao Zheng, Ying Han, Haiying Zhang
Article Number: 33
Published online on: 01 December 2025

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Bridging bench to bedside: Exosome‑based strategies for endometriosis diagnosis and treatment (Review)

Wanmeng Chen, Yujiu Ma, Xudong Zhang, Siwen Zhang, Shanshan Wu, Yimeng Lu, Jichun Tan
Article Number: 32
Published online on: 01 December 2025

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Retraction Open Access

[Retracted] miR‑381 functions as a tumor suppressor by targeting ETS1 in pancreatic cancer

Guanen Qiao, Jing Li, Jun Wang, Zhaoyang Wang, Wei Bian
Article Number: 31
Published online on: 01 December 2025

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March-2026 Volume 57 Issue 3

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Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Natural products as multi‑target therapies for sepsis‑induced myocardial dysfunction (Review)

Fei Tang, Dong Liu, Shi-Chao Zhu, Hui-Min Zhou, Xue-Wen Qiu
Article Number: 71
Published online on: 22 January 2026

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MTHFR‑folate axis as a modulator of the epigenetic landscape in autoimmune diseases (Review)

Pablo Michael Navarro‑Rodríguez, Ramón Francisco Bajeca‑Serrano, Francisco Javier Turrubiates‑Hernández, Hazael Ramiro Ceja‑Gálvez, Jorge Hernández‑Bello, Cristian Oswaldo Hernández‑Ramírez, Saúl Ramírez‑de Los Santos, José Francisco Muñoz‑Valle
Article Number: 70
Published online on: 22 January 2026

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Natural compound 5,7,8‑trimethoxyflavone mitigates radiation‑induced lung injury by suppressing EMT and PI3K/Akt pathway

Cui-Cui Gong, Hua-Kang Li, Yuan-Zhen Mi, Jun-Yang Chen, Zeng-Yi Fang, Shun-Lian Fu, Li Quan, Bing Lin, Jin-Yi Lang, Qiu Chen, Ke Xu, Mei-Hua Chen
Article Number: 69
Published online on: 21 January 2026

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Epigenetic dysregulation of B‑cells in autoimmune diseases and lymphomas (Review)

Yuxing Li, Yujiao Gong, Jiaxing Zhao, Rensen Ran
Article Number: 68
Published online on: 21 January 2026

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Research progress on the effects of macrophage‑derived exosomes on muscle factors IGF‑1 and FGF‑2 mediating musculoskeletal crosstalk molecular signaling pathway on bone metabolism (Review)

Ruo-Mei Cui, Mai Zheng, Jian-Bin Hong, Zheng-Xiang Wang, Yu-Fang Cun, Shu-Ji Gao, Yan-Lin Zhu, Zi-Bin Yang, Ming-Wei Liu
Article Number: 67
Published online on: 21 January 2026

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Expression of Concern Open Access

[Expression of Concern] Long non‑coding RNA SNHG20 promotes bladder cancer via activating the Wnt/β‑catenin signalling pathway

Qingsong Zhao, Saiyue Gao, Qingyan Du, Ye Liu
Article Number: 66
Published online on: 21 January 2026

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Mangiferin in human disease: Multifaceted mechanisms and applications (Review)

Yaling Dai, Qiuling Huang, Mengquan Tan, Zhifu Wang, Cai Jiang, Zheng Liu, Shenghang Zhang, Siyuan Song
Article Number: 65
Published online on: 21 January 2026

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Article

Deciphering the CAF‑LCN2 axis: Key to overcoming anti‑PD‑L1 immunotherapy resistance in lung cancer

Dan Xiao, Jing Yang, Jianying Zhou, Zhenzhen Hu, Ting Zhang
Article Number: 64
Published online on: 19 January 2026

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Retraction Open Access

[Retracted] DDAH2 alleviates myocardial fibrosis in diabetic cardiomyopathy through activation of the DDAH/ADMA/NOS/NO pathway in rats

Zhen-Dong Zhu, Ji-Ming Ye, Xue-Mei Fu, Xue-Chang Wang, Ji-Yun Ye, Xin-Ran Wu, Peng Hua, Yu-Qiong Liao, Wei Xuan, Jin-Lan Duan, Wei-Yuan Li, Hui Fu, Zhong-Hua Xia, Xuan Zhang
Article Number: 63
Published online on: 19 January 2026

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Beyond hepatic stellate cell heterogeneity: Resolving fibrosis, restoring regeneration (Review)

Chang Gao, Guiqing Chen, Hongyan Jia, Hong Zhu, Yun Cai, Dakai Yang, Kai Zhao
Article Number: 62
Published online on: 14 January 2026

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Correction Open Access

[Corrigendum] CDKN2A (p16INK4A) affects the anti‑tumor effect of CDK inhibitor in somatotroph adenomas

Yiyuan Chen, Zhenye Li, Qiuyue Fang, Hongyun Wang, Chuzhong Li, Hua Gao, Yazhuo Zhang
Article Number: 61
Published online on: 14 January 2026

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Review Open Access

Harnessing MSC‑derived exosomes to modulate the pathophysiology of ASD: Recent advances and therapeutic implications (Review)

Zhaojian Sun, Nouman Amjad, Majid Muhammad, Zhiyuan Li
Article Number: 60
Published online on: 13 January 2026

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Retraction Open Access

[Retracted] Mechanism of cell death induced by silica nanoparticles in hepatocyte cells is by apoptosis

Ye Yang, Xinjing Du, Qiang Wang, Jianwei Liu, Enguo Zhang, Linlin Sai, Cheng Peng, Martin F. Lavin, Abrey Jie Yeo, Xu Yang, Hua Shao, Zhongjun Du
Article Number: 59
Published online on: 12 January 2026

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ZG16B: A key regulator of tumor progression and immune microenvironment modulation in cancer (Review)

Xing-Ming Chen, Yu-Bo Liang, Jin-Xiang Zuo, Zi-Sheng Yang, Le-Yu Zhang, Xin-Yu Zhang, Ping Wan, Yang Ke
Article Number: 58
Published online on: 09 January 2026

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Retraction Open Access

[Retracted] Silica nanoparticles induce cardiomyocyte apoptosis via the mitochondrial pathway in rats following intratracheal instillation

Zhongjun Du, Shangya Chen, Guanqun Cui, Ye Yang, Enguo Zhang, Qiang Wang, Martin F. Lavin, Abrey J. Yeo, Cunxiang Bo, Yu Zhang, Chao Li, Xiaoshan Liu, Xu Yang, Cheng Peng, Hua Shao
Article Number: 57
Published online on: 05 January 2026

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Review Open Access

Role of cuproptosis in digestive system tumors (Review)

Li Zhang, Yongpeng Cheng, Lulu Tang, Jiaxing Zhu, Biguang Tuo
Article Number: 56
Published online on: 02 January 2026

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Review Open Access

Environmental exposure to air pollution and climate: Intersecting the impact on ear and nose health and chemosensory function (Review)

Yu-Chen Zhang, Lei Zhang, Ping-Ting Zhou, Zi-Hui Xie, Wen-Jie Zhang, Min Fan, Yan-Xun Han, Ye-Hai Liu, Yu-Chen Liu
Article Number: 55
Published online on: 31 December 2025

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Role and mechanisms of ferroptosis in cognitive impairment: From molecular pathways to therapeutic targets (Review)

Shenghui Ge, Deyue Kong, Shuyue Fan, Yi Luo, Xiao Yin, Zehua Jin, Wenqing Xia, Jianhua Ma
Article Number: 54
Published online on: 30 December 2025

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The GPR124‑Wnt‑PPARγ regulatory axis: Molecular mechanisms and therapeutic implications in chronic inflammatory diseases (Review)

Ming-Wang Cui, Si-Yu Tao, Tao Wen, Zhu-Ling Guo
Article Number: 53
Published online on: 30 December 2025

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Review Open Access

Advances in RPGR gene therapy for X‑linked retinitis pigmentosa: From preclinical insights to clinical application (Review)

Yushan Long, Jia Qi, Wenliang Zhang, Huan Qin, Kai Yao
Article Number: 52
Published online on: 30 December 2025

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