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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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International Journal of Molecular Medicine

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
November-2019 Volume 44 Issue 5

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review

The prospect of discovering new biomarkers for ovarian cancer based on current knowledge of susceptibility loci and genetic variation (Review)

Mikael Kronborg Christophersen, Claus Høgdall, Estrid Høgdall
Pages: 1599-1608
Published online on: 26 September 2019

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Article Open Access

Decreased collagen type III synthesis in skin fibroblasts is associated with parastomal hernia following colostomy

Fenglin Zhao, Fuqiang Chen, Xin Yuan, Yiting Liu, Jie Chen
Pages: 1609-1618
Published online on: 02 September 2019

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Article Open Access

MicroRNA‑379‑5p suppresses renal fibrosis by regulating the LIN28/let‑7 axis in diabetic nephropathy

Nan Li, Li‑Juan Wang, Wei‑Long Xu, Su Liu , Jiang‑Yi Yu
Pages: 1619-1628
Published online on: 30 August 2019

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Article Open Access

Conditioned medium derived from human amniotic stem cells delays H2O2‑induced premature senescence in human dermal fibroblasts

Changwei Pan, Hongxin Lang, Tao Zhang, Rui Wang, Xuewen Lin, Ping Shi, Feng Zhao, Xining Pang
Pages: 1629-1640
Published online on: 20 September 2019

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Article Open Access

Anti‑photoaging and anti‑oxidative activities of natural killer cell conditioned medium following UV‑B irradiation of human dermal fibroblasts and a reconstructed skin model

Sung‑Eun Lee, Tae‑Rin Kwon, Jong Hwan Kim, Byung‑Chul Lee, Chang Taek Oh, Minju Im, Yu Kyeong Hwang, Sang Hoon Paik, Seungryel Han, Jeom‑Yong Kim, Beom Joon Kim
Pages: 1641-1652
Published online on: 20 August 2019

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Article Open Access

A simplified 3D liver microsphere tissue culture model for hepatic cell signaling and drug-induced hepatotoxicity studies Corrigendum in /10.3892/ijmm.2023.5234

Ying Zhu, Qiong Shi, Qi Peng, Yue Gao, Ting Yang, Yu Cheng, Hao Wang, Yetao Luo, Ailong Huang, Tong‑Chuan He, Jiaming Fan
Pages: 1653-1666
Published online on: 21 August 2019

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Article Open Access

Knockdown of KLK12 inhibits viability and induces apoptosis in human colorectal cancer HT-29 cell line

Qianyuan Li, Xiukou Zhou, Zhengyu Fang, Huamiao Zhou
Pages: 1667-1676
Published online on: 30 August 2019

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Article Open Access

Incremental load training improves renal fibrosis by regulating the TGF‑β1/TAK1/MKK3/p38MAPK signaling pathway and inducing the activation of autophagy in aged mice Corrigendum in /10.3892/ijmm.2023.5274

Chuncha Bao, Zhong Yang, Qiyan Cai, Qian Li, Hongli Li, Bin Shu
Pages: 1677-1686
Published online on: 17 September 2019

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Article Open Access

Piperlongumine induces autophagy in biliary cancer cells via reactive oxygen species-activated Erk signaling pathway

San‑Yuan Chen, Hsin‑Yi Huang, Han‑Pei Lin, Chiung‑Yao Fang
Pages: 1687-1696
Published online on: 23 August 2019

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Article Open Access

IL‑21/IL‑21R inhibit tumor growth and invasion in non‑small cell lung cancer cells via suppressing Wnt/β‑catenin signaling and PD‑L1 expression

Dan Xue, Ping Yang, Qiongying Wei, Xiaoping Li, Lan Lin, Tingyan Lin
Pages: 1697-1706
Published online on: 26 September 2019

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Article Open Access

Overexpressed CD39 mitigates sepsis‑induced kidney epithelial cell injury via suppressing the activation of NLR family pyrin domain containing 3

Meixia Yang, Linxin Lu, Zhiqin Kang, Tianlong Ma, Yu Wang
Pages: 1707-1718
Published online on: 23 September 2019

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Article Open Access

Comprehensive circular RNA profiling reveals the regulatory role of the hsa_circ_0137606/miR‑1231 pathway in bladder cancer progression

Weijian Li, Youjian Li, Zhongxu Sun, Jun Zhou, Yuepeng Cao, Wenliang Ma, Kaipeng Xie, Xiang Yan
Pages: 1719-1728
Published online on: 17 September 2019

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Article Open Access

miR‑134‑5p/Foxp2/Syn1 is involved in cognitive impairment in an early vascular dementia rat model

Xin Liu, Ruilin Zhang, Zimei Wu, Wenwen Si, Zhenxing Ren, Saixia Zhang, Jianhong Zhou, Dongfeng Chen
Pages: 1729-1740
Published online on: 05 September 2019

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Article Open Access

Polyphenol mixture of a native Korean variety of Artemisia argyi H. (Seomae mugwort) and its anti‑inflammatory effects

Seong Min Kim, Soo Jung Lee, Venu Venkatarame Gowda Saralamma, Sang Eun Ha, Preethi Vetrivel, Kebede Taye Desta, Jin Young Choi, Won Sup Lee, Sung Chul Shin, Gon‑Sup Kim
Pages: 1741-1752
Published online on: 09 September 2019

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Article Open Access

Screening and identification of biomarkers for systemic sclerosis via microarray technology

Chen Xu, Ling‑Bing Meng, Yu‑Chen Duan, Yong‑Jing Cheng, Chun‑Mei Zhang, Xing Zhou, Ci‑Bo Huang
Pages: 1753-1770
Published online on: 05 September 2019

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Article Open Access

Fish oils protects against cecal ligation and puncture‑induced septic acute kidney injury via the regulation of inflammation, oxidative stress and apoptosis

Zhaoheng Lin, Jing Jin, Xiyun Shan
Pages: 1771-1780
Published online on: 11 September 2019

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Article Open Access

Connexin 43‑autophagy loop in the podocyte injury of diabetic nephropathy

Jialing Ji, Yajie Zhao, Chen Na, Min Yang, Xianyi Zhu, Huimin Shi, Weihua Gan, Aiqing Zhang
Pages: 1781-1788
Published online on: 10 September 2019

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Article Open Access

CUDC‑907 reverses pathological phenotype of keloid fibroblasts in vitro and in vivo via dual inhibition of PI3K/Akt/mTOR signaling and HDAC2

Tian Tu, Jia Huang, Miaomiao Lin, Zhen Gao, Xiaoli Wu, Wenjie Zhang, Guangdong Zhou, Wenbo Wang, Wei Liu
Pages: 1789-1800
Published online on: 23 September 2019

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Article Open Access

Improved HCN channels in pyramidal neurons and their new expression levels in pericytes and astrocytes in the gerbil hippocampal CA1 subfield following transient ischemia

Joon Ha Park, Dae Won Kim, Tae‑Kyeong Lee, Cheol Woo Park, Young Eun Park, Ji Hyeon Ahn, Hyang‑Ah Lee, Moo‑Ho Won, Choong‑Hyun Lee
Pages: 1801-1810
Published online on: 26 September 2019

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Article Open Access

Overexpression of miR‑200a‑3p promoted inflammation in sepsis‑induced brain injury through ROS‑induced NLRP3

Jianhua Yu, Jinlong Chen, Hualing Yang, Sifang Chen, Zhanxiang Wang
Pages: 1811-1823
Published online on: 30 August 2019

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Article Open Access

miR-217 inhibits the migration and invasion of HeLa cells through modulating MAPK1 Retraction in /10.3892/ijmm.2025.5525

Lihong Zhu, Shumei Yang, Jianfeng Wang
Pages: 1824-1832
Published online on: 02 September 2019

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Article Open Access

MicroRNA-939-5p directly targets IGF-1R to inhibit the aggressive phenotypes of osteosarcoma through deactivating the PI3K/Akt pathway Retraction in /10.3892/ijmm.2022.5181

Xiwu Zhao, Jian Li, Dapeng Yu
Pages: 1833-1843
Published online on: 05 September 2019

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Article Open Access

Comprehensive analysis of long non‑coding RNA‑messenger RNA‑microRNA co‑expression network identifies cell cycle‑related lncRNA in hepatocellular carcinoma

Hai‑Rong Zhu, Xiang‑Nan Yu, Guang‑Cong Zhang, Xuan Shi, Enkhnaran Bilegsaikhan, Hong‑Ying Guo, Li‑Li Liu, Yu Cai, Guang‑Qi Song, Tao‑Tao Liu, Ling Dong, Harry L.A. Janssen, Shu‑Qiang Weng, Jian Wu, Xi‑Zhong Shen, Ji‑Min Zhu
Pages: 1844-1854
Published online on: 23 August 2019

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Article Open Access

Piperlongumine reduces ovalbumin‑induced asthma and airway inflammation by regulating nuclear factor‑κB activation

Chun Lu, Bing Zhang, Tingting Xu, Wenxin Zhang, Bin Bai, Zhongxiang Xiao, Liqin Wu, Guang Liang, Yali Zhang, Yuanrong Dai
Pages: 1855-1865
Published online on: 21 August 2019

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Article Open Access

Kappa opioid receptor agonists improve postoperative cognitive dysfunction in rats via the JAK2/STAT3 signaling pathway

Xi Li, Yingjie Sun, Qiang Jin, Dandan Song, Yugang Diao
Pages: 1866-1876
Published online on: 13 September 2019

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Article Open Access

Quantitative proteomics reveal the alterations in the spinal cord after myocardial ischemia‑reperfusion injury in rats

Shun‑Yuan Li, Zhi‑Xiao Li, Zhi‑Gang He, Qian Wang, Yu‑Juan Li, Qing Yang, Duo‑Zhi Wu, Hao‑Long Zeng, Hong‑Bing Xiang
Pages: 1877-1887
Published online on: 17 September 2019

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Article Open Access

Identification of immunodominant IgE epitopes of the major house dust mite allergen Der f 24

Ze‑Lang Cai, Zhen Zhang, Wen‑Li Luo, Yi‑Bo Hou, Yong‑Shen He, Jia‑Jie Chen, Kunmei Ji
Pages: 1888-1898
Published online on: 18 September 2019

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Article Open Access

Ubiquitin‑proteasomes are the dominant mediators of the regulatory effect of microRNA‑1 on cardiac remodeling after myocardial infarction

Liping Wei, Yufan Zhang, Xin Qi, Xuseng Sun, Yuanyang Li, Yue Xu
Pages: 1899-1907
Published online on: 04 September 2019

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Article Open Access

Fatty liver and alteration of the gut microbiome induced by diallyl disulfide

Yanhong Yang, Fei Yang, Miaoling Huang, Huijuan Wu, Changyuan Yang, Xinyue Zhang, Lanxiang Yang, Guibin Chen, Shuqi Li, Qianyu Wang, Shaomin Liu, Yanyan Liu, Yuting Lei, Zili Lei, Jiao Guo
Pages: 1908-1920
Published online on: 24 September 2019

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Article Open Access

Role of IGFBP1 in the senescence of vascular endothelial cells and severity of aging‑related coronary atherosclerosis

Xiaojing Wu, Wei Zheng, Peng Jin, Junhao Hu, Qi Zhou
Pages: 1921-1931
Published online on: 12 September 2019

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Article Open Access

Isosteviol prevents the development of isoprenaline‑induced myocardial hypertrophy

Yaoxu Chen, Huimin Beng, Hao Su, Fuping Han, Zhuo Fan, Nanying Lv, Aleksandar Jovanović, Wen Tan
Pages: 1932-1942
Published online on: 17 September 2019

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Article Open Access

S‑allyl‑cysteine sulfoxide (alliin) alleviates myocardial infarction by modulating cardiomyocyte necroptosis and autophagy

Li‑Jun Yue, Xi‑Yu Zhu, Rui‑Sha Li, Hui‑Jing Chang, Bing Gong, Chong‑Chong Tian, Chang Liu, Yun‑Xing Xue, Qing Zhou, Tian‑Shu Xu, Dong‑Jin Wang
Pages: 1943-1951
Published online on: 26 September 2019

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Article Open Access

Metabolomic profiling identifies novel biomarkers and mechanisms in human bladder cancer treated with submucosal injection of gemcitabine

Chao Yang, Xian Sun, Hengbing Wang, Ting Lu, Keqing Wu, Yusheng Guan, Jing Tang, Jian Liang, Rongli Sun, Zhongying Guo, Sinian Zheng, Xiaoli Wu, Hesong Jiang, Xi Jiang, Bing Zhong, Xiaobing Niu, Suan Sun, Xinru Wang, Minjian Chen, Guangbo Fu
Pages: 1952-1962
Published online on: 23 September 2019

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Article

Activation of RXR by bexarotene inhibits inflammatory conditions in human rheumatoid arthritis fibroblast‑like synoviocytes

Yu Li, Qunzhi Xing, Yuanzhang Wei, Lei Zhao, Pei Zhang, Xuechang Han, Jing Wang
Pages: 1963-1970
Published online on: 10 September 2019

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Article

SKA1 overexpression is associated with the prognosis of esophageal squamous cell carcinoma and regulates cell proliferation and migration

Dongxin Hu, Zhen Li, Xiao Li, Honghao Fu, Mingyan Zhang
Pages: 1971-1978
Published online on: 17 September 2019

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Article

Indole‑6‑carboxaldehyde isolated from Sargassum thunbergii inhibits the expression and secretion of matrix metalloproteinase‑9

Tae‑Hee Kim, Soo‑Jin Heo, Seok‑Chun Ko, Won Sun Park, Il‑Whan Choi, Myunggi Yi, Won‑Kyo Jung
Pages: 1979-1987
Published online on: 20 August 2019

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Correction Open Access

[Corrigendum] c‑Myc regulates the CDK1/cyclin B1 dependent‑G2/M cell cycle progression by histone H4 acetylation in Raji cells

Yan Yang, Kai Xue, Zhi Li, Wei Zheng, Weijie Dong, Jiazhe Song, Shijie Sun, Tonghui Ma, Wenzhe Li
Pages: 1988-1988
Published online on: 20 August 2019

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Journal Cover
January-2026 Volume 57 Issue 1

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

FK506‑binding proteins as emerging bridges linking proteostasis to multi‑system pathogenesis and therapeutic strategies (Review)

Zhi Li, Xiaolei Liu, Hesong Zeng
Article Number: 30
Published online on: 24 November 2025

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Retraction Open Access

[Retracted] Suppression of SIK1 by miR‑141 in human ovarian cancer cell lines and tissues

Jin-Long Chen, Fang Chen, Ting-Ting Zhang, Nai-Fu Liu
Article Number: 29
Published online on: 24 November 2025

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Article Open Access

METTL3 inhibits LINC00312 to suppress osteoporosis progression in a YTHDF2‑dependent manner

Yang Wang, Yihao Tian, Gang Yao
Article Number: 28
Published online on: 20 November 2025

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Review Open Access

Decoding structural birth defects through genomic landscapes: Innovative frameworks for diagnosis (Review)

Ruihao Xu, Haoming Ren, Zhengwei Yuan, Wanqi Huang, Hui Gu
Article Number: 27
Published online on: 20 November 2025

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Article Open Access

MOTS‑c protects against placental injury via Nrf2 activation in hypoxia‑induced intrauterine growth restriction mice

Dan Chen, Hui-Min Zhao, Xiao-Lin Sun, Zhi-Xuan Xing, Sheng-Peng Li, Shuai-Chao Li, Ya-Xian Wu, Qing-Feng Pang, Jian-Feng Huang
Article Number: 26
Published online on: 18 November 2025

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Article Open Access

Synergistic effects of Akebia saponin D and Semaglutide on diabetic nephropathy and osteoporosis via the Klotho‑p53 signaling axis

Qian Zhang, Dan Wang, Hongxia Jia, Zongji Zheng, Liyan Lin, Linna Li, Ling Wang, Yaoming Xue
Article Number: 25
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑103 modulates tumor progression by targeting KLF7 in non‑small cell lung cancer

Ke Li, Conghu Yuan
Article Number: 24
Published online on: 17 November 2025

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Article

Comparative analysis of pan MHC‑I epitopes immunoreactivity on Hantaan virus nucleocapsid protein

Zhikui Li, Weijie Ding, Yubo Sun, Chenfeng Tian, Shuaishuai Fu, Fei Shi, Zhenchi Fang, Yuanzhe Li, Jianchang Li, Sirui Cai, Haobo Kang, Baozeng Sun, Junqi Zhang, Yuanjie Sun, Shuya Yang, Yusi Zhang, Chunmei Zhang, Yun Zhang, Xiyang Zhang, Kun Yang, Dongbo Jiang
Article Number: 23
Published online on: 14 November 2025

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Article Open Access

Human papillomavirus E7 inhibits immune responses in keratinocytes by activating HTRA1‑mediated mitophagy

Boya Zhang, Defeng Kong, Siji Chen, Xuewu Sun, Hao Cheng
Article Number: 22
Published online on: 14 November 2025

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Article Open Access

Targeting p38 MAPK signaling pathway: 
Quercetin as a novel therapy for TMJ synovitis

Mosha Cheng, Yuhe Guan, Xiaotao Xin, Xin Yi, Yi Liu
Article Number: 21
Published online on: 13 November 2025

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Review Open Access

Lipid droplets in astrocytes: Key organelles for CNS homeostasis and disease (Review)

Yuchen Wang, Boxuan Wang, Jinchao Hou, Xiaodong Huo, Chenlin Liu, Ruili Guan, Honggang Chen, Yang Zhou, Jianbin Zhang, Congcong Zhuang, Yuankang Zou
Article Number: 20
Published online on: 13 November 2025

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Review Open Access

Copper dyshomeostasis and cardiovascular disease: Molecular mechanisms and new strategies for targeted intervention with cuproptosis (Review)

Peiyu Li, Yinghui Li, Qian Meng, Jie Wang, Kun Wang, Sumin Yang
Article Number: 19
Published online on: 13 November 2025

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Article Open Access

Elevated FTO alleviates sepsis‑induced acute kidney injury by regulating macrophage inflammatory phenotypes

Xiaona Chen, Ziqi Sun, Jiabo Chen, Jinquan Zhang, Zeyu Liu, Zhengzheng Yan, Quan Li, Zhixia Chen
Article Number: 18
Published online on: 12 November 2025

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Correction Open Access

[Corrigendum]  Suppression of PAX6 promotes cell proliferation and inhibits apoptosis in human retinoblastoma cells

Bo Meng, Yisong Wang, Bin Li
Article Number: 17
Published online on: 10 November 2025

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Review Open Access

Microbial short chain fatty acids: Effective histone deacetylase inhibitors in immune regulation (Review)

Jing Wang, Qin Zhao, Shuwan Zhang, Jia Liu, Xingyue Fan, Bin Han, Yaqin Hou, Xiaopeng Ai
Article Number: 16
Published online on: 05 November 2025

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Review Open Access

High‑fat diet and cognitive dysfunction: Mechanistic insights into diet‑induced neurodegeneration (Review)

Min You, Fan Wu, Feng Xiong, Xue-Fei Hu, Huan Wu, Li Zhou, Hong-Xing Zhang
Article Number: 15
Published online on: 05 November 2025

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Article Open Access

ROCK inhibition promotes axon and myelin regeneration via PI3K/Akt/GSK3β in a mouse sciatic nerve injury model

Shuang Dou, Zhijun Li, Boyao Zheng, Zhenyu Ren, Hai Wang, Qing Zuo, Fang Fang, Yuehong Zhuang
Article Number: 14
Published online on: 05 November 2025

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Review Open Access

Mechanisms of mTORC1 and GCN2 amino acid sensing pathways in tumorigenesis and metastatic progression (Review)

Chaowei Zhang, Yuxuan Han, Weiyi Yao, Qing Hong, Na Chen
Article Number: 13
Published online on: 04 November 2025

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Review Open Access

β‑hydroxybutyric acid as a potential therapeutic metabolite for type 2 diabetes mellitus (Review)

Xianyi Ding, Jiabin Wu, Lian Wang, Ke Li, Haoyang Gao, Mingyu Wu, Qiuyu Zhang, Ruonan Han, Wenhong Wang, Weihua Xiao
Article Number: 12
Published online on: 03 November 2025

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Review

Histone lactylation: Unveiling a novel pathway for the impact of lactate on physiological and pathological processes (Review)

Xunjie Jian, Chang Cheng, Wenjie Lu, Hui Peng, Diqi Yang
Article Number: 11
Published online on: 03 November 2025

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Review Open Access

Interpretation of the molecular mechanism and therapeutic potential of microRNA‑155 in cardiovascular and cerebrovascular diseases (Review)

Xitong Zhao, Pengqin Wang
Article Number: 10
Published online on: 03 November 2025

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Expression of Concern Open Access

[Expression of Concern]  CDKN2A (p16INK4A) affects the anti‑tumor effect of CDK inhibitor in somatotroph adenomas

Yiyuan Chen, Zhenye Li, Qiuyue Fang, Hongyun Wang, Chuzhong Li, Hua Gao, Yazhuo Zhang
Article Number: 9
Published online on: 29 October 2025

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Article Open Access

TWEAK modulates the characteristics of periodontal ligament stem cells via the Fn14/NF‑κB pathway

Linlin Xiao, Man Qu, Lulu Chen, Mingli Xiang, Qian Long, Jianguo Liu, Xiaoyan Guan, Chengcheng Liao
Article Number: 8
Published online on: 27 October 2025

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Review Open Access

Harnessing copper: Innovative approaches to combat neurodegenerative diseases and cancer (Review)

Tao Duan, Hanhai Mao, Xingyue Jiang, Ying Tian, Jidong Zhang, Jun Tan
Article Number: 7
Published online on: 27 October 2025

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Retraction Open Access

[Retracted] Effects of miR‑106b‑3p on cell proliferation and epithelial‑mesenchymal transition, and targeting of ZNRF3 in esophageal squamous cell carcinoma

Guanen Qiao, Chenguang Dai, Yang He, Junjie Shi, Chunfang Xu
Article Number: 6
Published online on: 27 October 2025

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Review Open Access

Immune and metabolic remodeling following bariatric surgery: Implications for targeted immunotherapy (Review)

Yiming Shao, Ke Song, Ruixin Yu, He Xiao, Chengjun Li, Yuling Deng, Yuan Zhang, Yixing Ren
Article Number: 5
Published online on: 24 October 2025

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Article Open Access

Exportin 1 inhibitor KPT‑330 reverses oxaliplatin resistance via p53 nuclear retention in colorectal cancer

Chuanxi Lai, Xiya Jia, Yiyi Chen, Kangke Chen, Fei Wang, Qiqi Zhang, Xiaonan Xiang, Zhe-Sheng Chen, Lingna Xu, Sheng Dai
Article Number: 4
Published online on: 23 October 2025

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Article Open Access

Targeting of CIRP attenuates osteoarthritis progression via suppressing TLR4/NF‑κB/NLRP3 signaling axis

Weichao Sun, Yi Liao, Jianguo Feng, Jianhui Liang, Qifei He, Yinxing Cui, Dixi Huang, Houyin Shi, Wei You, Wei Sun, Qian Yi
Article Number: 3
Published online on: 23 October 2025

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Review

Importance of B cells (Review)

Zhiyuan Liu, Haoran Dai, Xiaoyu Cui, Yeping Liu, Zhaocheng Dong
Article Number: 2
Published online on: 22 October 2025

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Retraction Open Access

[Retracted] Hypoxic preconditioned bone mesenchymal stem cells ameliorate spinal cord injury in rats via improved survival and migration

Weiheng Wang, Xiaodong Huang, Wenbo Lin, Yuanyuan Qiu, Yunfei He, Jiangming Yu, Yanhai Xi, Xiaojian Ye
Article Number: 1
Published online on: 22 October 2025

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Journal Cover
February-2026 Volume 57 Issue 2

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

FGF4 alleviates the lung cell damage caused by high glucose via AMPK‑PGC‑1 signaling axis in vitro and in vivo

Qiujuan Fu, Yongfang Ou, Qin Wu, Jue Gong, Feixia Li, Tuxing Wang, Zhitai Lin, Kejie Huang, Jianlong Xie
Article Number: 39
Published online on: 05 December 2025

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Article Open Access

STOML2 interacts with PHB to activate the MEK/ERK signaling pathway and mediates autophagy‑related proteins in the progression of hepatocellular carcinoma

Haoyang Hu, Haozhe Zhang, Shuai Han, Jianli Chen, Ying Xie
Article Number: 38
Published online on: 04 December 2025

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Article Open Access

HMGB1 mediates low-dose ionizing radiation-induced Wnt/β-catenin activation in SRA01/04 cells: Mechanistic clues to early cataractogenesis

Ping Wang, Chunnan Piao, Dong Yan, Yingxue He, Yaru Li, Li Fan, Mei Tian
Article Number: 37
Published online on: 04 December 2025

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Article Open Access

FBXO22 promotes hepatocellular carcinoma progression via paracrine myo‑inositol‑induced M2‑type polarization of macrophages

Liangliang Bai, Jing Xiong, Sihai Chen, Jiahao Hu, Meixia Zhang, Bimin Li, Jing Hu, Mingyan He
Article Number: 36
Published online on: 02 December 2025

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Review Open Access

Branched‑chain amino acid metabolism and bone metabolism: Implications for osteoporosis pathogenesis and therapeutic strategies (Review)

Qi Xiao, Haimin Zeng, Ruhui Yang, Yuxin Zhan, Fangzhen Lin, Bofan Chen, Xiang Chen
Article Number: 35
Published online on: 02 December 2025

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Review Open Access

Mitochondria-associated endoplasmic reticulum membranes: Emerging regulators of cardiac microvascular ischemia/reperfusion injury (Review)

Yan Wang, Baowei Feng, Yanting Wu, Zongle Sun, Hao Yuan, Wei Chen, Chang Zhao, Zhi Liu
Article Number: 34
Published online on: 02 December 2025

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Review Open Access

Role of matrix metalloproteinases in the invasion of glioblastoma and drug interventions (Review)

Bohao Zheng, Ying Han, Haiying Zhang
Article Number: 33
Published online on: 01 December 2025

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Review

Bridging bench to bedside: Exosome‑based strategies for endometriosis diagnosis and treatment (Review)

Wanmeng Chen, Yujiu Ma, Xudong Zhang, Siwen Zhang, Shanshan Wu, Yimeng Lu, Jichun Tan
Article Number: 32
Published online on: 01 December 2025

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Retraction Open Access

[Retracted] miR‑381 functions as a tumor suppressor by targeting ETS1 in pancreatic cancer

Guanen Qiao, Jing Li, Jun Wang, Zhaoyang Wang, Wei Bian
Article Number: 31
Published online on: 01 December 2025

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