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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
October-2022 Volume 26 Issue 4

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Journal Metrics

Impact Factor: 3.5

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

The epigenetic impact of suberohydroxamic acid and 5‑Aza‑2'‑deoxycytidine on DNMT3B expression in myeloma cell lines differing in IL‑6 expression

Katerina Smesny Trtkova, Petra Luzna, Denisa Weiser Drozdkova, Katerina Cizkova, Lucie Janovska, Jan Gursky, Dana Prukova, Ivo Frydrych, Marian Hajduch, Jiri Minarik
Article Number: 321
Published online on: 29 August 2022

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Palmitoyl‑RGD promotes the expression of dermal‑epidermal junction components in HaCaT cells

Joo Hyuck Lim, Jung Soo Bae, Seung Ki Lee, Dong Hun Lee
Article Number: 320
Published online on: 29 August 2022

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Article Open Access

CTPS cytoophidia formation affects cell cycle progression and promotes TSN‑induced apoptosis of MKN45 cells

Xuepeng Fu, Wen Chen, Yang Pan, Chang Liu, Zhenzhu Zhang, Shuli Shao, Weiwei Zhang
Article Number: 319
Published online on: 29 August 2022

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Article Open Access

Angiotensin II receptor type 1 blocker candesartan improves morphine tolerance by reducing morphine‑induced inflammatory response and cellular activation of BV2 cells via the PPARγ/AMPK signaling pathway

Wenxin Zhao, Feiyan Shen, Jixiang Yao, Shanshan Su, Zhongmin Zhao
Article Number: 318
Published online on: 25 August 2022

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Article

SAC3D1 activates Wnt/β‑catenin signalling in hepatocellular carcinoma

Haitao Wang, Xiufang Shi
Article Number: 317
Published online on: 24 August 2022

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Retraction Open Access

[Retracted] MicroRNA-199b targets the regulation of ZEB1 expression to inhibit cell proliferation, migration and invasion in non‑small cell lung cancer

Jin Wang, Fachen Zhou, Liu Yin, Lei Zhao, Yixiang Zhang, Jinguang Wang
Article Number: 316
Published online on: 19 August 2022

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Retraction Open Access

[Retracted] Downregulation of microRNA‑198 suppresses cell proliferation and invasion in retinoblastoma by directly targeting PTEN

Dongdong Wei, Yingbin Miao, Lianxia Yu, Degong Wang, Yingli Wang
Article Number: 315
Published online on: 19 August 2022

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Article Open Access

Binaprofen induces zebrafish liver injury via the mitochondrial pathway

Qiuping Guo, Guiying Chen, Huiyu Ou, Ruomin Jin, Qingchun Ni, Renan Qin
Article Number: 314
Published online on: 17 August 2022

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Article Open Access

Downregulation of BLM RecQ helicase inhibits proliferation, promotes the apoptosis and enhances the sensitivity of bladder cancer cells to cisplatin

Sujuan Feng, Xiaosong Qian, Dalin Feng, Xiaodong Zhang
Article Number: 313
Published online on: 17 August 2022

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Article Open Access

Oridonin attenuates dextran sulfate sodium‑induced ulcerative colitis in mice via the Sirt1/NF‑κB/p53 pathway

Maonan Wang, Bo Xu, Lintao Liu, Dawei Wang
Article Number: 312
Published online on: 17 August 2022

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Correction Open Access

[Corrigendum] High glucose promotes hepatic fibrosis via miR‑32/MTA3‑mediated epithelial‑to‑mesenchymal transition

Qiang Li, Zhange Li, Yuan Lin, Hui Che, Yingying Hu, Xujuan Kang, Ying Zhang, Lihong Wang, Yong Zhang
Article Number: 311
Published online on: 16 August 2022

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Retraction Open Access

[Retracted] microRNA‑188 acts as a tumour suppressor in glioma by directly targeting the IGF2BP2 gene

Li Ding, Ling Wang, Feng Guo
Article Number: 310
Published online on: 16 August 2022

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Article Open Access

Identification of circular RNA biomarkers for Pien Tze Huang treatment of CCl4‑induced liver fibrosis using RNA‑sequencing

Ting Wang, Jinhang Zhu, Longhui Gao, Muyun Wei, Di Zhang, Luan Chen, Hao Wu, Jingsong Ma, Lixing Li, Na Zhang, Yanjing Wang, Qinghe Xing, Lin He, Fei Hong, Shengying Qin
Article Number: 309
Published online on: 12 August 2022

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Article Open Access

MW‑9, a chalcones derivative bearing heterocyclic moieties, attenuates experimental autoimmune encephalomyelitis via suppressing pathogenic TH17 cells

Bei Liu, Zewei Mao, Na Yin, Qianlan Gu, Yan Qi, Xiaosi Li, Haihao Yang, Zhao Wu, Nanting Zou, Sai Ying, Chunping Wan
Article Number: 308
Published online on: 11 August 2022

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Correction Open Access

[Corrigendum] Benzyl isothiocyanate suppresses development and metastasis of murine mammary carcinoma by regulating the Wnt/β‑catenin pathway

Bei Xie, Lei Zhao, Lanlan Guo, Hang Liu, Siyu Fu, Wenjuan Fan, Li Lin, Jing Chen, Bei Wang, Linlan Fan, Hulai Wei
Article Number: 307
Published online on: 10 August 2022

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Article Open Access

Puerarin attenuates isoproterenol‑induced myocardial hypertrophy via inhibition of the Wnt/β‑catenin signaling pathway

Xiaoying Wang, Kai He, Linlin Ma, Lan Wu, Yan Yang, Yanfei Li
Article Number: 306
Published online on: 09 August 2022

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Article Open Access

SDF‑1α/CXCR4 signaling promotes capillary tube formation of human retinal vascular endothelial cells by activating ERK1/2 and PI3K pathways in vitro

Xianbin Yuan, Hongya Wu, Xin Li, Lei Chen, Yanhui Xiao, Zhigang Chen, Gaoqin Liu, Peirong Lu
Article Number: 305
Published online on: 09 August 2022

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Article Open Access

FOXC1‑mediated TRIM22 regulates the excessive proliferation and inflammation of fibroblast‑like synoviocytes in rheumatoid arthritis via NF‑κB signaling pathway

Yazhi Wei, Xinmin Huang, Yanmei Ma, Liping Dai
Article Number: 304
Published online on: 09 August 2022

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Review Open Access

Role of ROS‑mediated autophagy in melanoma (Review)

Xuebing Zhang, Huaijun Li, Chengxiang Liu, Xingxing Yuan
Article Number: 303
Published online on: 09 August 2022

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Article Open Access

Lutein inhibits IL‑6 expression by inducing PPAR‑γ activation and SOCS3 expression in cerulein‑stimulated pancreatic acinar cells

Yu Jin Ahn, Joo Weon Lim, Hyeyong Kim
Article Number: 302
Published online on: 09 August 2022

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Retraction Open Access

[Retracted] MicroRNA‑454 inhibits tumor cell proliferation, migration and invasion by downregulating zinc finger E‑box‑binding homeobox 1 in gastric cancer

Zhe Song, Wei Li, Liang Wang, Nan Jia, Baosheng Chen
Article Number: 301
Published online on: 08 August 2022

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Review Open Access

Biological and neurological activities of astaxanthin (Review)

Pan Si, Chenkai Zhu
Article Number: 300
Published online on: 08 August 2022

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Article Open Access

Hydroxygenkwanin suppresses proliferation, invasion and migration of osteosarcoma cells via the miR‑320a/SOX9 axis

Xinli Dong, Yanhua Wang, Hua Zhuang, Gang An
Article Number: 299
Published online on: 05 August 2022

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Review Open Access

Functional characteristics and research trends of PDE11A in human diseases (Review)

Gyeyeong Kong, Hyunji Lee, Thuy-Trang T. Vo, Uijin Juang, So Hee Kwon, Jisoo Park, Jongsun Park, Seon-Hwan Kim
Article Number: 298
Published online on: 04 August 2022

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Article Open Access

LncRNA GAS5 promotes spermidine‑induced autophagy through the miRNA‑31‑5p/NAT8L axis in pulmonary artery endothelial cells of patients with CTEPH

Qinghua Wu, Xiaohui Zhou, Yan Wang, Yamin Hu
Article Number: 297
Published online on: 02 August 2022

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Article Open Access

Analysis of CXCL8 and its receptors CXCR1/CXCR2 at the mRNA level in neoplastic tissue, as well as in serum and peritoneal fluid in patients with ovarian cance

Marta Smycz‑Kubańska, Sebastian Stępień, Joanna Magdalena Gola, Celina Kruszniewska‑Rajs, Dominika Wendlocha, Patrycja Królewska‑Daszczyńska, Anna Strzelec, Jarosław Strzelczyk, Wojciech Szanecki, Andrzej Witek, Aleksandra Mielczarek‑Palacz
Article Number: 296
Published online on: 02 August 2022

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Retraction Open Access

[Retracted] miR‑202 functions as a tumor suppressor in non‑small cell lung cancer by targeting STAT3

Zhonghai Zhao, Bin Lv, Li Zhang, Nana Zhao, Yan Lv
Article Number: 295
Published online on: 02 August 2022

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Journal Cover
July-2026 Volume 34 Issue 1

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Journal Metrics

Impact Factor: 3.5

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Editorial Open Access

Regulatory mechanisms and therapeutic potential of N6-methyladenosine modification in retinal diseases (Review)

Wenyao Zhang, Jinying Chen, Jingxiang Zhong
Article Number: 213
Published online on: 29 May 2026

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Review Open Access

Epigenetic orchestration of scar formation: Therapeutic potential of targeting DNA methylation and non‑coding RNAs in cutaneous fibrosis (Review)

Jinshun Li, Weiyun Liu, Jin Yang, Yanan Li
Article Number: 212
Published online on: 29 May 2026

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Review Open Access

Elucidating the multitarget neuroprotective mechanisms of protocatechuic acid in neurological disorders (Review)

Xiaoyan Xue, Yongchang Lai, Shasha Song, Liping Wu, Lifang Wang
Article Number: 211
Published online on: 29 May 2026

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Retraction Open Access

[Retracted] Piperine depresses the migration progression via downregulating the Akt/mTOR/MMP‑9 signaling pathway in DU145 cells

Yuan Zeng, Ying Yang
Article Number: 210
Published online on: 27 May 2026

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Article Open Access

FOSL2 drives transcriptional activation of super‑enhancer-regulated DYNC1H1 to promote hypoxia‑induced oral squamous cell carcinoma progression

Linyu Jin, Jing Zhang, Wenjing Wang, Nan Zhang, Yang Liu, Alin Tian, Weiwei Yin, Yongle Qiu
Article Number: 209
Published online on: 25 May 2026

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Review Open Access

Targeting lipophagy in atherosclerosis: Molecular mechanisms, pathogenesis and therapeutic interventions (Review)

Songhua Nan, Chaojie Peng, Xue Meng, Jingnan Jia, Fangfang Zhao, Yinglin Cui
Article Number: 208
Published online on: 22 May 2026

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Review Open Access

Mechanisms of pruritus and advances in traditional Chinese medicine therapy (Review)

Hailing Zhang, Yongji Li, Yuan Liu, Danyi Feng, Letao Zhao, Ran Chen, Xiwu Zhang, Jinjin Dou
Article Number: 207
Published online on: 22 May 2026

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Review Open Access

Reprogramming of the hepatic ubiquitin‑immune axis: A unifying mechanism in liver disease progression (Review)

Yadi Ju, Xiaodan Chong, Weichen Ning, Yan Shi, Yangyang Li, Yihai Shi
Article Number: 206
Published online on: 22 May 2026

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Review Open Access

Role of the PI3K/AKT signaling pathway in regulating gene expression in rheumatoid arthritis (Review)

Chengzhi Cong, Yuan Wang, Jian Liu, Chao Jin
Article Number: 205
Published online on: 21 May 2026

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Review Open Access

Biomarkers of radioresistance in lung cancer: Current insights and future directions (Review)

Fatima Zohra Attouahri, Imane Chaoui, Abdelilah Laraqui, Mohamed Rida Tagajdid, Mohammed Oukabli, Mohammed El Marjany, Meriem Khyatti, Mohammed Attaleb, Mouna Ababou, Khalid Ennibi, Khaoula Errafii, Mohammed El Mzibri
Article Number: 204
Published online on: 21 May 2026

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Review Open Access

Epigenetic research methods and animal models for intervertebral disc degeneration (Review)

Xinliang Cui, Li Zeng, Wei Zhang, Leimin Xi, Rui Wang, Diff Jia, Safa, Haoyu Feng, Huidong Jia
Article Number: 203
Published online on: 21 May 2026

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Article Open Access

ZBTB16 upregulation maintains copper homeostasis to support esophageal tumor progression

Jingyi Wang, Bin Yang, Shengzu Peng, Bin Yang
Article Number: 202
Published online on: 21 May 2026

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Correction Open Access

[Corrigendum] MicroRNA‑1 promotes cartilage matrix synthesis and regulates chondrocyte differentiation via post‑​transcriptional suppression of Ihh expression  

Taoyu Chen, Xianda Che, Pengfei Han, Jiangong Lu, Chunfang Wang, Bin Liang, Ziqi Hou, Xiaochun Wei, Lei Wei, Pengcui Li
Article Number: 201
Published online on: 20 May 2026

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Review Open Access

Estrogen deficiency as a common driver and integrative mechanism in osteoporosis‑osteoarthritis comorbidity (Review)

Jian Cheng, Xiaodong Wu, Lu Zhao, Shuai Jiang, Wenjie Zhao, Weishuai Zhang
Article Number: 200
Published online on: 20 May 2026

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Review Open Access

Role of RNA 5‑methylcytosine modification in cancer: Insights from coding and non‑coding RNAs (Review)

Qin Jiang, Yi Gong, Mimi Zhai, Tenglong Tang, Sushun Liu
Article Number: 199
Published online on: 20 May 2026

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Review Open Access

m6A modification in skeletal system diseases (Review)

Xi Xie, Chen Li, Haotian Zheng, Guang Gan, Xi Gao
Article Number: 198
Published online on: 19 May 2026

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Review Open Access

Dynamic regulation of the ‘mitochondria‑immune axis’ in myocardial infarction: Molecular mechanisms driving macrophage polarization through energy metabolism disorders (Review)

Yu Zhang, Hao Feng, Qin Wu, Shuxian Yang, Yundong Jiang, Houping Xu, Li Dong, Xiaolin Li, Hui Chen, Gang Luo
Article Number: 197
Published online on: 19 May 2026

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Retraction Open Access

[Retracted] Homeobox B9 facilitates hypertrophic scar formation via activating the mitogen‑activated protein kinase signaling pathway

Qun Xie, Dandan Liu, Mosheng Yu, Xiaowei Wu, Yueqiang Zhao, Qiang Hu, Qi Wang
Article Number: 196
Published online on: 18 May 2026

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Review Open Access

Polysaccharides: Natural candidates for targeting immunometabolic regulation in hepatocellular carcinoma (Review)

Changmei Wu, Jinjin Dou, Xiwu Zhang
Article Number: 195
Published online on: 18 May 2026

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Article Open Access

NF‑κB signaling drives Th17‑mediated lacrimal gland injury and tear dysfunction in a murine model of primary Sjögren's syndrome

Jiajun Xie, Huina Zhang, Wenyue Shen, Juan Ye
Article Number: 194
Published online on: 18 May 2026

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Review Open Access

POSTN(+) fibroblasts and SPP1(+) macrophages in scar formation: A review of mechanisms and therapeutic targets (Review)

Haotian Wu, Xianglin Dong
Article Number: 193
Published online on: 15 May 2026

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Review Open Access

Emerging role of DYRK1A as a target in cardiovascular diseases (Review)

Liqing Yu, Qionghong Cheng, Jun Wu
Article Number: 192
Published online on: 15 May 2026

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Retraction Open Access

[Retracted] Resveratrol pretreatment attenuates traumatic brain injury in rats by suppressing NLRP3 inflammasome activation via SIRT1

Peng Zou, Xiaoxiao Liu, Gang Li, Yangang Wang
Article Number: 191
Published online on: 05 May 2026

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Review Open Access

Gut microbiota and its metabolites: Key factors of drug resistance in the treatment of advanced prostate cancer (Review)

Jingheng Song, Hongguo Cui, Peisen Yang, Yankai Xu, Yuanyuan Liu, Gang Zhang, Yangyang Liu, Aimin Tian, Jizhong Che, Hui Sun, Zhengchao Zhang
Article Number: 190
Published online on: 04 May 2026

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Article Open Access

Cepharanthine inhibits lysosomes and induces apoptosis in triple‑negative breast cancer cells

Juan Li, Siqin Zhou, Yu Wang, Guanghan Ou, Danli Yang, Liwen Shen
Article Number: 189
Published online on: 04 May 2026

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Review Open Access

Applications of humanized mice in Mycobacterium tuberculosis infections (Review)

Binghua Han, Fang Liu, Jinzhao Long, Jiongjiong Wang, Yange Cui, Haiyan Yang
Article Number: 188
Published online on: 04 May 2026

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Review Open Access

Research progress on neutrophil extracellular traps in sepsis‑induced coagulopathy (Review)

Jiandong Hu, Mengli Jin, Zhihua Cao, Binbin Zheng, Yuan Zheng, Hao Shen
Article Number: 187
Published online on: 04 May 2026

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Review Open Access

Multifaceted regulatory role of proline‑ and glutamine-rich splicing factor in tumors (Review)

Shilin Zhang, Zhenhua Li, Li Fu
Article Number: 186
Published online on: 04 May 2026

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Article Open Access

Effects of ALDH2 gene expression on the oxidative stress‑mediated NF‑κB/mTOR pathway in ketamine‑induced cystitis

Xiao Jian Xi, Yong Yao, Peng Gu, Min Hao Zhang
Article Number: 185
Published online on: 04 May 2026

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Retraction Open Access

[Retracted] Rosiglitazone exerts neuroprotective effects via the suppression of neuronal autophagy and apoptosis in the cortex following traumatic brain injury

Junchao Yao, Kebin Zheng, Xiang Zhang
Article Number: 184
Published online on: 29 April 2026

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Journal Cover
August-2026 Volume 34 Issue 2

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Journal Metrics

Impact Factor: 3.5

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Retraction Open Access

[Retracted] Tripterygium glycoside suppresses epithelial‑to‑­­ mesenchymal transition of diabetic kidney disease podocytes by targeting autophagy through the mTOR/Twist1 pathway

Mei Tao, Danna Zheng, Xudong Liang, Diandian Wu, Kang Hu, Juan Jin, Qiang He
Article Number: 225
Published online on: 08 June 2026

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Gut microbiota‑derived metabolites in cardiovascular disease: Focus on trimethylamine N‑oxide, short‑chain fatty acids and bile acids (Review)

Meizhu Gao, Zhenming Hao, Yiling Li, Weixue Liu, Fubao Zhang
Article Number: 224
Published online on: 08 June 2026

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Article Open Access

Fucoxanthin alleviates chondrocyte inflammation and osteoarthritis by modulating the JAK2/STAT3 signaling pathway

Miradj Siddick Adam, Huangming Zhuang, Xunshan Ren, Yuelong Zhang, Panghu Zhou
Article Number: 223
Published online on: 08 June 2026

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Article Open Access

Prediction of molecular targets for zedoary turmeric oil in inhibiting proliferation and inducing apoptosis in non‑small cell lung cancer

Huaiyong Li, Lili Liu, Qingzhu Yang, Yao Li, Yongli Song, Jing Jiang, Zhenzhong Wu, Weiwei Zhang, Baisong Lou
Article Number: 222
Published online on: 08 June 2026

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Review Open Access

Molecular mechanisms of iron metabolism and ferroptosis in cardiovascular diseases and intervention strategies targeting natural products (Review)

Liangqing Ge, Tianqing Zhang, Jiangbiao Yu, Sijie Xiao, Yu Zhou, Li Luo
Article Number: 221
Published online on: 05 June 2026

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Correction Open Access

[Corrigendum] Electroacupuncture at GV20‑GB7 regulates mitophagy to protect against neurological deficits following intracerebral hemorrhage via inhibition of apoptosis

Ruiqiao Guan, Zhihao Li, Xiaohong Dai, Wei Zou, Xueping Yu, Hao Liu, Qiuxin Chen, Wei Teng, Peng Liu, Xiaoying Liu, Shanshan Dong
Article Number: 220
Published online on: 03 June 2026

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Article Open Access

LINC01117 promotes the malignant proliferation of lung adenocarcinoma by increasing HOXD8 mRNA stability

Lizhong Zeng, Jie Shi, Cai Zhang, Yujiao Dong, Yang Chen, Qiuhong Zhang, Long Zhang, Shuanying Yang
Article Number: 219
Published online on: 03 June 2026

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Article Open Access

Targeting regulatory T cells in the prostate cancer microenvironment: From mechanisms to therapeutics (Review)

Hua Luo
Article Number: 218
Published online on: 03 June 2026

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Article Open Access

Dapagliflozin alleviates heart failure with preserved ejection fraction potentially by regulating the AIM2/caspase‑1/GSDMD pathway and attenuating pyroptosis

Sailiang Ding, Hao Yang, Ting Lu, Yibin Luo, Liang Xu, Xianghui Zeng
Article Number: 217
Published online on: 03 June 2026

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Retraction Open Access

[Retracted] Carnosic acid alleviates brain injury through NF‑κB‑regulated inflammation and Caspase‑3‑associated apoptosis in high fat‑induced mouse models

Yong Liu, Yan Zhang, Ming Hu, Yu-Hu Li, Xing-Hua Cao
Article Number: 216
Published online on: 02 June 2026

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Review Open Access

SIRT1/AMPK/PGC1α pathway in ischemic stroke: Elucidating neuroprotective strategies (Review)

Irum Naz Abbasi, Nashwa Amin, Qiaolu Xu, Azhar Badry Hussain, Fei Wu, Xia Yuan, Yang Yang, Suhong Ye, Marong Fang, Yihua Jiang
Article Number: 215
Published online on: 02 June 2026

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Review Open Access

Beyond the primary site: Molecular insights and clinical implications of cancer metastatic overlap between lung and urological organ cancers (Review)

Yinhuan Wang, Jiefang Guan
Article Number: 214
Published online on: 29 May 2026

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