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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
October-2022 Volume 26 Issue 4

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Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

The epigenetic impact of suberohydroxamic acid and 5‑Aza‑2'‑deoxycytidine on DNMT3B expression in myeloma cell lines differing in IL‑6 expression

Katerina Smesny Trtkova, Petra Luzna, Denisa Weiser Drozdkova, Katerina Cizkova, Lucie Janovska, Jan Gursky, Dana Prukova, Ivo Frydrych, Marian Hajduch, Jiri Minarik
Article Number: 321
Published online on: 29 August 2022

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Palmitoyl‑RGD promotes the expression of dermal‑epidermal junction components in HaCaT cells

Joo Hyuck Lim, Jung Soo Bae, Seung Ki Lee, Dong Hun Lee
Article Number: 320
Published online on: 29 August 2022

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CTPS cytoophidia formation affects cell cycle progression and promotes TSN‑induced apoptosis of MKN45 cells

Xuepeng Fu, Wen Chen, Yang Pan, Chang Liu, Zhenzhu Zhang, Shuli Shao, Weiwei Zhang
Article Number: 319
Published online on: 29 August 2022

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Article Open Access

Angiotensin II receptor type 1 blocker candesartan improves morphine tolerance by reducing morphine‑induced inflammatory response and cellular activation of BV2 cells via the PPARγ/AMPK signaling pathway

Wenxin Zhao, Feiyan Shen, Jixiang Yao, Shanshan Su, Zhongmin Zhao
Article Number: 318
Published online on: 25 August 2022

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Article

SAC3D1 activates Wnt/β‑catenin signalling in hepatocellular carcinoma

Haitao Wang, Xiufang Shi
Article Number: 317
Published online on: 24 August 2022

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Retraction Open Access

[Retracted] MicroRNA-199b targets the regulation of ZEB1 expression to inhibit cell proliferation, migration and invasion in non‑small cell lung cancer

Jin Wang, Fachen Zhou, Liu Yin, Lei Zhao, Yixiang Zhang, Jinguang Wang
Article Number: 316
Published online on: 19 August 2022

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Retraction Open Access

[Retracted] Downregulation of microRNA‑198 suppresses cell proliferation and invasion in retinoblastoma by directly targeting PTEN

Dongdong Wei, Yingbin Miao, Lianxia Yu, Degong Wang, Yingli Wang
Article Number: 315
Published online on: 19 August 2022

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Article Open Access

Binaprofen induces zebrafish liver injury via the mitochondrial pathway

Qiuping Guo, Guiying Chen, Huiyu Ou, Ruomin Jin, Qingchun Ni, Renan Qin
Article Number: 314
Published online on: 17 August 2022

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Article Open Access

Downregulation of BLM RecQ helicase inhibits proliferation, promotes the apoptosis and enhances the sensitivity of bladder cancer cells to cisplatin

Sujuan Feng, Xiaosong Qian, Dalin Feng, Xiaodong Zhang
Article Number: 313
Published online on: 17 August 2022

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Article Open Access

Oridonin attenuates dextran sulfate sodium‑induced ulcerative colitis in mice via the Sirt1/NF‑κB/p53 pathway

Maonan Wang, Bo Xu, Lintao Liu, Dawei Wang
Article Number: 312
Published online on: 17 August 2022

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Correction Open Access

[Corrigendum] High glucose promotes hepatic fibrosis via miR‑32/MTA3‑mediated epithelial‑to‑mesenchymal transition

Qiang Li, Zhange Li, Yuan Lin, Hui Che, Yingying Hu, Xujuan Kang, Ying Zhang, Lihong Wang, Yong Zhang
Article Number: 311
Published online on: 16 August 2022

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Retraction Open Access

[Retracted] microRNA‑188 acts as a tumour suppressor in glioma by directly targeting the IGF2BP2 gene

Li Ding, Ling Wang, Feng Guo
Article Number: 310
Published online on: 16 August 2022

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Article Open Access

Identification of circular RNA biomarkers for Pien Tze Huang treatment of CCl4‑induced liver fibrosis using RNA‑sequencing

Ting Wang, Jinhang Zhu, Longhui Gao, Muyun Wei, Di Zhang, Luan Chen, Hao Wu, Jingsong Ma, Lixing Li, Na Zhang, Yanjing Wang, Qinghe Xing, Lin He, Fei Hong, Shengying Qin
Article Number: 309
Published online on: 12 August 2022

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MW‑9, a chalcones derivative bearing heterocyclic moieties, attenuates experimental autoimmune encephalomyelitis via suppressing pathogenic TH17 cells

Bei Liu, Zewei Mao, Na Yin, Qianlan Gu, Yan Qi, Xiaosi Li, Haihao Yang, Zhao Wu, Nanting Zou, Sai Ying, Chunping Wan
Article Number: 308
Published online on: 11 August 2022

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Correction Open Access

[Corrigendum] Benzyl isothiocyanate suppresses development and metastasis of murine mammary carcinoma by regulating the Wnt/β‑catenin pathway

Bei Xie, Lei Zhao, Lanlan Guo, Hang Liu, Siyu Fu, Wenjuan Fan, Li Lin, Jing Chen, Bei Wang, Linlan Fan, Hulai Wei
Article Number: 307
Published online on: 10 August 2022

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Puerarin attenuates isoproterenol‑induced myocardial hypertrophy via inhibition of the Wnt/β‑catenin signaling pathway

Xiaoying Wang, Kai He, Linlin Ma, Lan Wu, Yan Yang, Yanfei Li
Article Number: 306
Published online on: 09 August 2022

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Article Open Access

SDF‑1α/CXCR4 signaling promotes capillary tube formation of human retinal vascular endothelial cells by activating ERK1/2 and PI3K pathways in vitro

Xianbin Yuan, Hongya Wu, Xin Li, Lei Chen, Yanhui Xiao, Zhigang Chen, Gaoqin Liu, Peirong Lu
Article Number: 305
Published online on: 09 August 2022

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FOXC1‑mediated TRIM22 regulates the excessive proliferation and inflammation of fibroblast‑like synoviocytes in rheumatoid arthritis via NF‑κB signaling pathway

Yazhi Wei, Xinmin Huang, Yanmei Ma, Liping Dai
Article Number: 304
Published online on: 09 August 2022

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Review Open Access

Role of ROS‑mediated autophagy in melanoma (Review)

Xuebing Zhang, Huaijun Li, Chengxiang Liu, Xingxing Yuan
Article Number: 303
Published online on: 09 August 2022

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Article Open Access

Lutein inhibits IL‑6 expression by inducing PPAR‑γ activation and SOCS3 expression in cerulein‑stimulated pancreatic acinar cells

Yu Jin Ahn, Joo Weon Lim, Hyeyong Kim
Article Number: 302
Published online on: 09 August 2022

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Retraction Open Access

[Retracted] MicroRNA‑454 inhibits tumor cell proliferation, migration and invasion by downregulating zinc finger E‑box‑binding homeobox 1 in gastric cancer

Zhe Song, Wei Li, Liang Wang, Nan Jia, Baosheng Chen
Article Number: 301
Published online on: 08 August 2022

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Review Open Access

Biological and neurological activities of astaxanthin (Review)

Pan Si, Chenkai Zhu
Article Number: 300
Published online on: 08 August 2022

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Article Open Access

Hydroxygenkwanin suppresses proliferation, invasion and migration of osteosarcoma cells via the miR‑320a/SOX9 axis

Xinli Dong, Yanhua Wang, Hua Zhuang, Gang An
Article Number: 299
Published online on: 05 August 2022

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Functional characteristics and research trends of PDE11A in human diseases (Review)

Gyeyeong Kong, Hyunji Lee, Thuy-Trang T. Vo, Uijin Juang, So Hee Kwon, Jisoo Park, Jongsun Park, Seon-Hwan Kim
Article Number: 298
Published online on: 04 August 2022

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Article Open Access

LncRNA GAS5 promotes spermidine‑induced autophagy through the miRNA‑31‑5p/NAT8L axis in pulmonary artery endothelial cells of patients with CTEPH

Qinghua Wu, Xiaohui Zhou, Yan Wang, Yamin Hu
Article Number: 297
Published online on: 02 August 2022

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Article Open Access

Analysis of CXCL8 and its receptors CXCR1/CXCR2 at the mRNA level in neoplastic tissue, as well as in serum and peritoneal fluid in patients with ovarian cance

Marta Smycz‑Kubańska, Sebastian Stępień, Joanna Magdalena Gola, Celina Kruszniewska‑Rajs, Dominika Wendlocha, Patrycja Królewska‑Daszczyńska, Anna Strzelec, Jarosław Strzelczyk, Wojciech Szanecki, Andrzej Witek, Aleksandra Mielczarek‑Palacz
Article Number: 296
Published online on: 02 August 2022

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Retraction Open Access

[Retracted] miR‑202 functions as a tumor suppressor in non‑small cell lung cancer by targeting STAT3

Zhonghai Zhao, Bin Lv, Li Zhang, Nana Zhao, Yan Lv
Article Number: 295
Published online on: 02 August 2022

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Journal Cover
March-2026 Volume 33 Issue 3

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article

CTRP4 ameliorates dexamethasone‑induced insulin resistance through the IRS‑1/PI3K/AKT pathway in 3T3‑L1 adipocytes

Maireyanmu Rouzi, Xi Sun, Luguang Sheng, Bilin Xu, Tao Lei, Jun Lu, Jie Gao
Article Number: 101
Published online on: 27 January 2026

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Article Open Access

PTUPB, a soluble epoxide hydrolase/cyclooxygenase‑2 dual inhibitor, reduces endothelial‑to‑mesenchymal transition and improves doxorubicin‑induced vascular and cardiac toxicity

Hevna Dhulkifle, Lubna Therachiyil, Maram H. Hasan, Shahd M. Younis, Nizar A. Al‑Shar'i, Huseyin C. Yalcin, Zaid H. Maayah
Article Number: 100
Published online on: 27 January 2026

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Retraction Open Access

[Retracted] miR‑367 enhances the proliferation and invasion of cutaneous malignant melanoma by regulating phosphatase and tensin homolog expression

Jianwen Long, Jing Luo, Xuwen Yin
Article Number: 99
Published online on: 26 January 2026

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Review Open Access

Advances in the mechanisms of the NLRP3 inflammasome in sepsis‑induced cardiomyopathy and targeted therapeutic studies 
(Review)

Yifei Chen, Zhaohui Zhang, Gaosheng Zhou
Article Number: 98
Published online on: 22 January 2026

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Article Open Access

HMGN2 induces pyroptosis in tumour cells by modulating the STT3B/PD‑L1/caspase‑1/GSDMD axis

Wenwen Han, Hongli Chen, Bomiao Cui, Jiao Chen, Ping Zhang, Yun Feng
Article Number: 97
Published online on: 22 January 2026

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Article Open Access

Naringin ameliorates intestinal injury in ulcerative colitis model mice by modulating the JAK2/STAT3 signaling pathway

Miaomiao Wu, Yating An, Yongmin Li, Wei He, Ying Wang, Yaqi Wang, Caixia Wu
Article Number: 96
Published online on: 22 January 2026

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Review

PDX1 in human cancers: Molecular mechanisms, dual roles and clinical implications (Review)

Chen Zhou, Yifei Wang, Jie Zhao, Yantao Yang, Yuhang Yuan, Xiaochen Hou, Yu Tang, Lianhua Ye
Article Number: 95
Published online on: 22 January 2026

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Retraction Open Access

[Retracted] Autophagy flux inhibition mediated by celastrol sensitized lung cancer cells to TRAIL‑induced apoptosis via regulation of mitochondrial transmembrane potential and reactive oxygen species

Uddin Md Nazim, Honghua Yin, Sang-Youel Park
Article Number: 94
Published online on: 19 January 2026

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Review Open Access

Converting ‘cold’ to ‘hot’ hepatocellular carcinoma for improved immunotherapy (Review)

Ching-Hua Hsieh, Pei-Chin Chuang
Article Number: 93
Published online on: 15 January 2026

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Article Open Access

Pathological mechanism of ferroptosis in a rat model of α‑naphthyl isothiocyanate‑induced chronic cholestasis

Zhen Guo, Jiaxuan Wang, Yiwen Wang, Xinzhu Liu, Yubing Xia, Ping Liu, Li Qi, Jia Liu, Xiaoning Wang
Article Number: 92
Published online on: 14 January 2026

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Correction Open Access

[Corrigendum] Role of hypoxia‑inducible factor‑1α and CD146 in epidermal growth factor receptor‑mediated angiogenesis in salivary gland adenoid cystic carcinom

Wei-Ming Wang, Zhi-Li Zhao, Wen-Feng Zhang, Yi-Fang Zhao, Lu Zhang, Zhi-Jun Sun
Article Number: 91
Published online on: 13 January 2026

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Review Open Access

Klebsiella pneumoniae and pyogenic liver abscess: Emerging clinical threats, virulence mechanisms and therapeutic strategies (Review)

Gulam Mustafa Hasan, Taj Mohammad, Sobia Zaidi, Anas Shamsi, Sukhwinder Singh Sohal, Md. Imtaiyaz Hassan
Article Number: 90
Published online on: 13 January 2026

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Article Open Access

Collagen III regulates the termination of liver regeneration by suppressing hepatocyte proliferation and promoting functional recovery

Haiyang Peng, Zhiyong Chen, Qiwei Zhang, Yuezhou Zhang, Peng Yang, Jianping Gong, Andong Zhao
Article Number: 89
Published online on: 13 January 2026

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Review Open Access

Application of extracellular vesicles in the diagnosis and treatment of chronic obstructive pulmonary disease (Review)

Yixin Zhang, Tong Ren, Jianbo Xue, Yan Yu, Xianqiang Zhou, Xiaoyi Hu, Wenyi Yu, Zhancheng Gao, Cuiling Feng
Article Number: 88
Published online on: 13 January 2026

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Article Open Access

Cigarette smoke combined with Klebsiella pneumoniae induce damage to the air‑blood barrier in chronic obstructive pulmonary disease rats via the MAPK/NF‑κB/IκBα pathway

Yange Tian, Kexin Xu, Ruilong Lu, Kangchen Li, Xuejie Shao, Yixi Liao, Yakun Zhao, Zhiguang Qiu, Haoran Dong, Xuefang Liu
Article Number: 87
Published online on: 12 January 2026

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Retraction Open Access

[Retracted] 8‑bromo‑7‑methoxychrysin induces apoptosis by regulating Akt/FOXO3a pathway in cisplatin‑sensitive and resistant ovarian cancer cells

Qing Ding, Yi Chen, Qing Zhang, Yanling Guo, Zhi Huang, Liqing Dai, Sudan Cao
Article Number: 86
Published online on: 12 January 2026

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Article Open Access

Anxiety‑induced overactive bladder: The role of oxidative stress and NF‑κB signaling pathway with Hsp90 as a potential biomarker

Zhipeng Zhou, Lina Xu, Han Wu, Huaishan Hong
Article Number: 85
Published online on: 12 January 2026

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Article Open Access

Echinacoside alleviates asthenozoospermia by upregulating Sox5‑mediated transcriptional activation of the CatSper gene

Zi-Run Jin, Yong-Wei Huo, Bo-Heng Liu, Hong Tian, Shuo Yuan, Yue Tian, Ke Xi, Jie Cai, Hui Jiang, Yong Jiang, Guo-Gang Xing
Article Number: 84
Published online on: 12 January 2026

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Article Open Access

Artemisiae Scopariae Herba (Yinchen) suppresses ferroptosis in mice with osteoporosis via the Nrf2/Slc7a11/Gpx4 pathway

Pei Li, Xinyu Wan, Wenjie Li, Ding Cheng, Ying Yang, Yuhan Wang, Ruyuan Zhu, Yanjing Chen, Haixia Liu, Zhiguo Zhang
Article Number: 83
Published online on: 12 January 2026

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Review Open Access

Prolyl hydroxylase domain proteins: Localization, regulation, function and their role in erythropoiesis (Review)

Yan Hou, Zhao-Hua Zhang, Wen-Qian Li, Guo-Xiong Han, Kuo Shen, You-Bang Xie
Article Number: 82
Published online on: 12 January 2026

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Therapeutic potential of saponins for allergic rhinitis: Molecular mechanisms and clinical perspectives (Review)

Bing-Yu Liang, Zi-Yue Fu, Fen-Fen Li, Ping-Ting Zhou, Zi-Hui Xie, Ke Han, Yan-Xun Han, Shan-Wen Chen, Yi Zhao, Hai-Feng Pan, Ye-Hai Liu, Yu-Chen Liu
Article Number: 81
Published online on: 07 January 2026

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Interleukin‑6 and ischemic stroke: From mechanisms to clinical prospects (Review)

Xinyue Wang, Xiaohang Zhang, Jianing Lin, Ping Lin
Article Number: 80
Published online on: 05 January 2026

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Article Open Access

Preliminary exploration of the putative function of SF3A2 in clear cell renal cell carcinoma

Ru Chen, Jie Xu
Article Number: 79
Published online on: 05 January 2026

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Retraction Open Access

[Retracted] TIPE‑2 suppresses growth and aggressiveness of hepatocellular carcinoma cells through downregulation of the phosphoinositide 3‑kinase/AKT signaling pathway

Lin Wang, Chen Chen, Shuzhi Feng, Jianli Tian
Article Number: 78
Published online on: 05 January 2026

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Journal Cover
April-2026 Volume 33 Issue 4

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

N6‑methyladenosine reader insulin‑like growth factor 2 mRNA‑binding protein 2 promotes abnormal proliferation of colonic epithelial cells in type 2 diabetes mellitus by regulating midkine

Jieyao Li, Qingsheng Xie, Jihao Xu
Article Number: 108
Published online on: 04 February 2026

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Expression of Concern Open Access

[Expression of Concern] Curcumin suppresses breast tumor angiogenesis by abrogating osteopontin‑induced VEGF expression

Goutam Chakraborty, Shalini Jain, Smita Kale, Remya Raja, Santosh Kumar, Rosalin Mishra, Gopal C. Kundu
Article Number: 107
Published online on: 04 February 2026

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Review Open Access

Research status and molecular mechanisms of disulfidptosis in cardiovascular diseases (Review)

Xiao Jin, Zelin Cheng, Xinyue Ding, Zongjun Liu
Article Number: 106
Published online on: 03 February 2026

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Article Open Access

Role and mechanism of tetrahedral DNA nanostructures in the repair of urethral injury in rats

Caifen Guo, Jian Li
Article Number: 105
Published online on: 02 February 2026

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Retraction Open Access

[Retracted] MicroRNA‑4500 suppresses tumor progression in non‑small cell lung cancer by regulating STAT3

Zhi-Ying Li, Zi-Zhou Zhang, Hui Bi, Qiu-Di Zhang, Su-Juan Zhang, Lin Zhou, Xiao-Qin Zhu, Jun Zhou
Article Number: 104
Published online on: 02 February 2026

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Article Open Access

Integrative bioinformatics and experimental analysis reveals FRA1 as a key mediator of tubulointerstitial inflammation in lupus nephritis

Wenpeng Ni, Jialin He, Zhouyu Zeng, Jialong Ke, Runpei Lin, Jianming Peng, Kunyi Deng, Lijuan Wen, Yanhui Chen, Chilun Zhang, Yanfen Li, Guanghong Gu
Article Number: 103
Published online on: 28 January 2026

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Correction Open Access

[Corrigendum] Resveratrol improves neurological outcome and neuroinflammation following spinal cord injury through enhancing autophagy involving the AMPK/mTOR pathway

Hong-Yu Meng, De-Cheng Shao, Han Li, Xiao-Dan Huang, Guang Yang, Bing Xu, Hai-Yun Niu
Article Number: 102
Published online on: 28 January 2026

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