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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
April 2013 Volume 7 Issue 4

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

Association of the COMT Met158 allele with trait impulsivity in healthy young adults

Márcio Gerhardt Soeiro-De-Souza, Matthew S. Stanford, Danielle Soares Bio, Rodrigo Machado-Vieira, Ricardo Alberto Moreno
Pages: 1067-1072
Published online on: 21 February 2013

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Article Open Access

The role of the mitochondrial calcium uniporter in cerebral ischemia/reperfusion injury in rats involves regulation of mitochondrial energy metabolism

Qin Zhao, Shilei Wang, Yu Li, Peng Wang, Shuhong Li, Yunliang Guo, Ruyong Yao
Pages: 1073-1080
Published online on: 18 February 2013

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Article Open Access

Low‑grade inflammation in the rectum of patients with sporadic irritable bowel syndrome

Magdy El‑Salhy, Doris Gundersen, Jan Gunnar Hatlebakk, Trygve Hausken
Pages: 1081-1085
Published online on: 14 February 2013

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Article

PLAG1 and CYLD do not play a role in the tumorigenesis of adenoid cystic carcinoma

Tsutomu Daa, Itaru Nakamura, Naomi Yada, Shigeki Arakane, Haruto Nishida, Kenji Kashima, Masashi Suzuki, Shigeo Yokoyama
Pages: 1086-1090
Published online on: 06 February 2013

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Article

Sivelestat sodium hydrate reduces radiation-induced lung injury in mice by inhibiting neutrophil elastase

Nobuhiko Yoshikawa, Taisuke Inomata, Yoshikatsu Okada, Taiju Shimbo, Masatsugu Takahashi, Kazuhiko Akita, Yasuo Uesugi, Yoshifumi Narumi
Pages: 1091-1095
Published online on: 08 February 2013

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Article

Therapeutic potential of EGCG on acute renal damage in a rat model of obstructive nephropathy

Ping Zhou, Jin Feng Yu, Cheng Guang Zhao, Feng Xuan Sui, Xu Teng, Yu Bin Wu
Pages: 1096-1102
Published online on: 28 January 2013

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Article

Peiminine ameliorates bleomycin-induced acute lung injury in rats

Hai Guo, Fuzhi Ji, Baorui Liu, Xiaofei Chen, Jingdong He, Jiening Gong
Pages: 1103-1110
Published online on: 07 February 2013

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Article

Participation of CD34-enriched mouse adipose cells in hair morphogenesis

Jing He, Huichuan Duan, Yao Xiong, Wenjie Zhang, Guangdong Zhou, Yilin Cao, Wei Liu
Pages: 1111-1116
Published online on: 05 February 2013

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Article

Altered melatonin secretion and circadian gene expression with increased proinflammatory cytokine expression in early-stage sepsis patients

Cai-Xia Li, Dong-Dong Liang, Guo-Hao Xie, Bao-Li Cheng, Qi-Xing Chen, Shui-Jing Wu, Jun-Lu Wang, William Cho, Xiang-Ming Fang
Pages: 1117-1122
Published online on: 20 February 2013

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Article

Propofol induces rat embryonic neural stem cell apoptosis by activating both extrinsic and intrinsic pathways

Wei-Wei Zou, Hua-Ping Xiao, Miao-Ning Gu, Ke-Xuan Liu, Zhi-Qun Liu
Pages: 1123-1128
Published online on: 29 January 2013

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Article

Evaluation of the proliferation and differentiation behaviors of mesenchymal stem cells with partially converted borate glass containing different amounts of strontium in vitro

Yi Zhu, Yuanming Ouyang, Yi Chang, Congfeng Luo, Jun Xu, Changqing Zhang, Wenhai Huang
Pages: 1129-1136
Published online on: 26 February 2013

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Article

The role of the TLR4 signaling pathway in cognitive deficits following surgery in aged rats

Yi Wang, Huijuan He, Dan Li, Wenjing Zhu, Kaiming Duan, Yuan Le, Yan Liao, Yangwen Ou
Pages: 1137-1142
Published online on: 18 February 2013

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Article

Chordin‑like protein 1 promotes neuronal differentiation by inhibiting bone morphogenetic protein‑4 in neural stem cells

Wei‑Lu Gao, Sheng‑Quan Zhang, Hui Zhang, Bo Wan, Zong‑Sheng Yin
Pages: 1143-1148
Published online on: 06 February 2013

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Article

Growth inhibition effect of peptide P110 plus cisplatin on various cancer cells and xenotransplanted tumors in mice

Ming Li, Jun Wang, Shi‑Yun Tan, Jian‑Hua Chen, Wei Cui, Zhi‑Qiang Chen, Jian Zhang
Pages: 1149-1154
Published online on: 26 February 2013

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Article

The effects of carvedilol on cardiac structural remodeling: The role of endogenous nitric oxide in the activity of carvedilol

Jiangbin Chen, Congxin Huang, Bin Zhang, Qiao Huang, Jing Chen, Lin Xu
Pages: 1155-1158
Published online on: 19 February 2013

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Article

Altered expression of PTCH and HHIP in gastric cancer through their gene promoter methylation: Novel targets for gastric cancer

Yu Song, Ye Tian, Yun Zuo, Jian-Cheng Tu, Yu-Fang Feng, Chen-Jiang Qu
Pages: 1159-1168
Published online on: 21 February 2013

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Article

The role of the serum RANKL/OPG ratio in the healing of intertrochanteric fractures in elderly patients

Xue-Fei Wang, Ya-Kui Zhang, Zhen-Shan Yu, Jun-Lin Zhou
Pages: 1169-1172
Published online on: 21 February 2013

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Article

Mechanism of chronic dietary iron overload‑induced liver damage in mice

Dan Liu, Huan He, Dong Yin, Ailing Que, Lei Tang, Zhangping Liao, Qiren Huang, Ming He
Pages: 1173-1179
Published online on: 08 February 2013

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Article

Inhibitory effect of ARHI on pancreatic cancer cells and NF‑κB activity

Yi‑Qun Hu, Li‑Juan Si, Zhen‑Shi Ye, Zhen‑He Lin, Jing‑Ping Zhou
Pages: 1180-1184
Published online on: 26 February 2013

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Article

Probucol inhibits hydrogen peroxide to induce apoptosis of vascular smooth muscle cells

Lin Sheng, Bo Jiao, Lijuan Shao, Shaojie Bi, Chao Cheng, Jingbo Zhang, Yihao Jiang
Pages: 1185-1190
Published online on: 29 January 2013

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Article

A randomized, open-label clinical trial using optical coherence tomography to compare two sirolimus-eluting stents, one with a biodegradable polymer and the other with a permanent polymer

Feng Tian, Yundai Chen, Changfu Liu, Qinhua Jin, Lian Chen, Zhijun Sun, Hongbin Liu, Jun Guo, Luyue Gai
Pages: 1191-1196
Published online on: 07 February 2013

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Article

Aberrant production of soluble inducible T‑cell co‑stimulator (sICOS) and soluble programmed cell death protein 1 (sPD‑1) in patients with chronic hepatitis C

Dongsheng Wang, Ding'an Zhou, Qin Du, Qi Liang, Qiang Wang, Li Fang, Guangrong Wang, Quming Fan, Beizhong Liu, Jingguo Zhou, Zhong Tang, Hao Wu, Xiaolan Guo, Yanmei Jiao, Guoyuan Zhang
Pages: 1197-1202
Published online on: 19 February 2013

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Article

A high‑fat diet induces obesity and impairs bone acquisition in young male mice

Xiao‑Mei Lu, Hong Zhao, En‑Hua Wang
Pages: 1203-1208
Published online on: 29 January 2013

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Article

Detection of tyrosine‑phosphorylated proteins in hepatocellular carcinoma tissues using a combination of GST‑Nck1‑SH2 pull‑down and two‑dimensional electrophoresis

Fanghua Qiu, Dehong Huang, Hongguang Xiao, Fangying Qiu, Liming Lu, Jing Nie
Pages: 1209-1214
Published online on: 19 February 2013

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Article

Recombinant attenuated Salmonella typhimurium carrying a plasmid co-expressing ENDO-VEGI151 and survivin siRNA inhibits the growth of breast cancer in vivo

Zhe Li, Pei-Hao Yin, Sheng-Sheng Yang, Qian-Yu Li, Tao Chang, Lin Fang, Lin-Xiang Shi, Guo-En Fang
Pages: 1215-1222
Published online on: 05 February 2013

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Article

Sinomenine inhibits the expression of PD‑L1 in the peripheral blood mononuclear cells of mesangial proliferative nephritis patients

Yue Cheng, Furong Li, Daihong Wang, Ying Zhang, Fahuan Yuan, Jingbo Zhang
Pages: 1223-1228
Published online on: 01 February 2013

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Article

Type II, but not type I, cGMP-dependent protein kinase reverses bFGF-induced proliferation and migration of U251 human glioma cells

Zhi-Hong Cao, Yan Tao, Jian-Rong Sang, Yin-Jie Gu, Xiu-Juan Bian, Yong-Chang Chen
Pages: 1229-1234
Published online on: 11 February 2013

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Article

H2O2 inhibits the growth of human pulmonary fibroblast cells by inducing cell death, GSH depletion and G1 phase arrest

Woo Hyun Park
Pages: 1235-1240
Published online on: 01 February 2013

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Article Open Access

Reduced chromogranin A cell density in the ileum of patients with irritable bowel syndrome

Magdy El-Salhy, Ingvild Haukaas Wendelbo, Doris Gundersen
Pages: 1241-1244
Published online on: 19 February 2013

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Article

Gene expression levels of cytokines in peripheral blood mononuclear cells from patients with pulmonary embolism

Wei Lv, Qianglin Duan, Lemin Wang, Zhu Gong, Fan Yang, Yanli Song
Pages: 1245-1250
Published online on: 26 February 2013

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Article

shRNAs targeting high‑mobility group box-1 inhibit E-selectin expression via homeobox A9 in human umbilical vein endothelial cells

Xiao-Juan Zhang, Zheng-Gang Luan, Xiao-Chun Ma
Pages: 1251-1256
Published online on: 07 February 2013

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Article

hcrcn81 is upregulated by rapamycin treatment in human colorectal adenocarcinoma cells

Xiaoxia Wen, Lei Dong, Jianjun Zhu, Yao Chen
Pages: 1257-1260
Published online on: 08 February 2013

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Article

Relevance of IL-6 and MMP-9 to cerebral arteriovenous malformation and hemorrhage

Xiong Li, Rong Wang, Xuejiang Wang, Xiaowei Xue, Duan Ran, Shuo Wang
Pages: 1261-1266
Published online on: 20 February 2013

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Article

The effect of a proton pump inhibitor on bone metabolism in ovariectomized rats

Moon Kyung Joo, Jong-Jae Park, Beom Jae Lee, Ji Hoon Kim, Jong Eun Yeon, Jae Seon Kim, Kwan Soo Byun, Young-Tae Bak
Pages: 1267-1272
Published online on: 19 February 2013

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Article

The expression of NMDA receptor and pCREB in the visual cortex of monocularly‑deprived rats

Xiaonan Sun, Jinsong Zhang
Pages: 1273-1277
Published online on: 01 February 2013

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Article

Hypoglycemic effects of glabridin, a polyphenolic flavonoid from licorice, in an animal model of diabetes mellitus

Feihua Wu, Zhigui Jin, Jian Jin
Pages: 1278-1282
Published online on: 19 February 2013

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Article

Inhibition of proliferation of estrogen receptor‑positive MCF‑7 human breast cancer cells by tamoxifen through c‑Jun transcription factors

Yan Xu, Shi‑Tao Zou, Ran Zhu, Wei Li, Chun‑Wei Gu, Shao‑Hua Wei, Jia‑Ming Xie, Hao‑Rong Wu
Pages: 1283-1287
Published online on: 05 February 2013

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Article

Antiproliferative activity of Alpinia officinarum extract in the human breast cancer cell line MCF-7

Sungho Ghil
Pages: 1288-1292
Published online on: 05 February 2013

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Article

Oxymatrine protects against myocardial injury via inhibition of JAK2/STAT3 signaling in rat septic shock

Minghao Zhang, Xiuyu Wang, Xiumei Wang, Xiaolin Hou, Peng Teng, Yideng Jiang, Linna Zhang, Xiaoling Yang, Jue Tian, Guizhong Li, Jun Cao, Hua Xu, Yunhong Li, Yin Wang
Pages: 1293-1299
Published online on: 08 February 2013

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Article

Role of TRPV1 and P2X receptors in the activation of lung vagal C-fiber afferents by inhaled cigarette smoke in rats

Wen-Hui Weng, Chun-Chun Hsu, Ling-Ling Chiang, Yi-Jiun Peter Lin, You Shuei Lin, Chien-Ling Su
Pages: 1300-1304
Published online on: 30 January 2013

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Article

Human endogenous retrovirus-H insertion screening

Mehrab Guliyev, Sibel Yilmaz, Kaniye Sahin, Sevgi Marakli, Nermin Gozukirmizi
Pages: 1305-1309
Published online on: 28 January 2013

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Article

Association between the endothelial nitric oxide synthase gene Glu298Asp polymorphism and coronary heart disease: A meta‑analysis of 39 case‑control studies

Guo‑Xiang Tian, Xian‑Tao Zeng, Xiao‑Bing Wang, Ling Zhang, Wei Zhang, Wan‑Lin Wei
Pages: 1310-1318
Published online on: 30 January 2013

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Article

Effect of a BK viruria reaction detected by qualitative polymerase chain reaction on the renal function of kidney transplant recipients

Ming‑Chang Hsieh, Ching‑Wen Hung, Hui‑Ling Chiou, Shun‑Fa Yang
Pages: 1319-1323
Published online on: 21 February 2013

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Article

Effects of the downregulation of SnoN expression on HepG2 cell proliferation and apoptosis

Wenqi Wang, Changhong Liu, Yiguo Wang, Lili Cao
Pages: 1324-1328
Published online on: 26 February 2013

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Article

IL-22 exacerbates the severity of CVB3-induced acute viral myocarditis in IL-17A-deficient mice

Qing Kong, Yimin Xue, Weifeng Wu, Fan Yang, Yanli Liu, Mengsha Gao, Wenyin Lai, Xiaofen Pan
Pages: 1329-1335
Published online on: 18 February 2013

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Article

Pioglitazone inhibits high glucose‑induced synthesis of extracellular matrix by NF‑κB and AP‑1 pathways in rat peritoneal mesothelial cells

Guangyu Zhou, Xuesong Su, Jianfei Ma, Lining Wang, Detian Li
Pages: 1336-1342
Published online on: 06 February 2013

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Article

Allitridin inhibits human cytomegalovirus replication in vitro

Ju Zhang, Hui Wang, Zhi-Dan Xiang, Sai-Nan Shu, Feng Fang
Pages: 1343-1349
Published online on: 19 February 2013

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Article

Effect of the PA‑MSHA vaccine on septic serum‑induced inflammatory response

Xiang‑Feng Liu, Li Wang, Yi Qu, De-Wu Zhong, Xiong-Ying Miao, Hong‑Liang Yao
Pages: 1350-1354
Published online on: 21 February 2013

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Article

Validation study of 131I‑RRL: Assessment of biodistribution, SPECT imaging and radiation dosimetry in mice

Qian Zhao, Ping Yan, Lei Yin, Ling Li, Xue Qi Chen, Chao Ma, Rong Fu Wang
Pages: 1355-1360
Published online on: 22 February 2013

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Article

Changes in serum IGF‑1 level and tumor VEGF expression in mice with colorectal cancer under hyperglycemic conditions

Hong Cao, Chunhui Jin, Defang Huang, Chao Liu, Daoqi Sun, Cheng Tan, Xiaoming Zhu, Yajun Fei
Pages: 1361-1365
Published online on: 26 February 2013

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Correction Open Access

[Corrigendum] Influence of lactoferrin in preventing preterm delivery: A pilot study

Giuliana Giunta, Lorena Giuffrida, Katia Mangano, Paolo Fagone, Antonio Cianci
Pages: 1366-1366
Published online on: 27 February 2013

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Journal Cover
January-2026 Volume 33 Issue 1

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Non‑coding RNAs in epithelial‑mesenchymal transition of renal cell carcinoma (Review)

Ziqiao Liu, Hanshen Zhou, Junxiao Shen, Yiming Qi, Xuke Gong, Cheng Zhang
Article Number: 51
Published online on: 24 November 2025

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Article Open Access

FOXJ3 drives mesenchymal stem cell osteogenic differentiation via the Wnt/β‑catenin pathway: A novel regulator implicated in osteoporosis

Hongwei Xiao, Jianfeng Li, Wei Huang, Yi Qin
Article Number: 50
Published online on: 21 November 2025

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Article Open Access

NEDD4 regulates VEGF signaling and mTOR to promote angiogenesis and the cell cycle in steroid‑induced osteonecrosis of the femoral head

Jian Li, Dong Zhen, Yuhuan Qin, Caifen Guo
Article Number: 49
Published online on: 21 November 2025

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Article Open Access

Glabridin attenuates LTA‑induced alveolar macrophage migration via activation of the Nrf2/HO‑1 pathway

Chih-Hsuan Hsia, Chun-Ming Yang, Chao-Chien Chang, Ting-Lin Yen, Arief Gunawan Darmanto, Chi-Chang Huang, Joen-Rong Sheu
Article Number: 48
Published online on: 21 November 2025

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Review Open Access

Research progress on molecular therapy for glaucoma (Review)

Weiwei Wang, Gangwei Cheng, Qi Zhou, Sheng Wang, Linyi Zhang
Article Number: 47
Published online on: 21 November 2025

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Article Open Access

Natural compounds for the treatment of rheumatoid arthritis based on the ‘gut‑joint axis’ (Review)

Wenjie Hu, Rui Li, Zhongming Zhang
Article Number: 46
Published online on: 20 November 2025

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Article Open Access

TGM1 as a novel signature gene in psoriasis identified by integrative bioinformatics and experimental validation

Pan Guo, Mengke Sun, Jingyu Zhang, Qianshu Yuan, Hong Cui, Junkai Huang, Jing Luo, Qianyu Zhu, Bingxin Zhang, Lizhi Hu
Article Number: 45
Published online on: 20 November 2025

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Article Open Access

CDK1‑induced regulation of p53 phosphorylation at Ser315 mediates cell cycle arrest and apoptosis of macrophages infected with clinical isolates of Mycobacterium tuberculosis

Banghao Sun, Zhenyu Zhao, Qingyu Meng, Luya Pu, Xingyu Jiang, Shuai Li, Fadi Cao, Fan Li
Article Number: 44
Published online on: 20 November 2025

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Article Open Access

High‑intensity exercise training inhibits excessive autophagy in the hyperlipidemic myocardium of ApoE‑/‑ mice via the NAD+‑mediated SIRT1/MFN2 pathway

Shan Gao, Wei Yao, Jin Yang, Yujie Liu, Zuowei Pei
Article Number: 43
Published online on: 18 November 2025

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Correction Open Access

[Corrigendum] Protective effects of metformin against myocardial ischemia‑reperfusion injury via AMPK‑dependent suppression of NOX4

Yan Shi, Shu-Ai Hou
Article Number: 42
Published online on: 17 November 2025

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Article Open Access

Apelin promotes RANKL‑mediated osteoclastogenesis by activating MAPK and NF‑κB pathways

Yu-Han Wang, Yu-Ying Wu, Chun-Hao Tsai, Yi-Chin Fong, Chih-Yuan Ko, Hsien-Te Chen, Yat-Yin Law, Chih-Hsin Tang
Article Number: 41
Published online on: 12 November 2025

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Identification of multimorbidity hub genes for knee osteoarthritis-atherosclerosis and potential clinical applications

Qingyuan Kang, Ping Yuan, Peisen Xie, Wentao Xiao, Liguang Dong, Zhenpeng Guan, Keshi Zhang
Article Number: 40
Published online on: 12 November 2025

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CTSB mediates oxidative stress and intestinal epithelial barrier disruption in intestinal ischemia‑reperfusion injury

Shuang He, Lei Wang, Zhe Wang, Shiyong Yu, Qi Zhu, Yijun Xu, Yuhang Jiang, Yingxia Wu, Honggang Xiang
Article Number: 39
Published online on: 12 November 2025

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Astragaloside IV promotes the apoptosis of pancreatic cancer cells by activating endoplasmic reticulum stress through the PERK/ATF4/CHOP signaling pathway

Yijun Wang, Mengyang Zhao, Shanshan Liu, Rui Zheng, Tianhui Gao
Article Number: 38
Published online on: 11 November 2025

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[Retracted] Baicalin inhibits influenza virus A replication via activation of type I IFN signaling by reducing miR‑146a

Rui Li, Lianxin Wang
Article Number: 37
Published online on: 10 November 2025

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Migrasomes: Emerging players in intercellular communication and disease pathogenesis (Review)

Yuanliang Cao, Quan Wan, Boqi Zhou, Haixin Zeng, Xiaojie Lu
Article Number: 36
Published online on: 10 November 2025

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Diabetic keratopathy and nuclear proteins (Review)

Haiying Xu, Zhi-Liang Jiang, Yuehong Wang, Xiaoli Hou, Weixia Dong, Yanfang Chen, Qiuying Zhang, Xinying Ji, Shaoping Ji, Yalong Dang
Article Number: 35
Published online on: 10 November 2025

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Homocystinuria: Advances in metabolic and molecular therapies targeting homocysteine pathways (Review)

Ayman A. Althubity
Article Number: 34
Published online on: 10 November 2025

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Synovial chondromatosis: Novel advances in understanding the pathogenesis and in diagnostic strategies (Review)

Xingzheng Deng, Shizhang Liu, Huitong Liu
Article Number: 33
Published online on: 10 November 2025

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Protective effects of Notoginsenoside R1 on the ferroptosis of a human non‑small cell lung cancer cell line

Yuejiao Zhang, Zhongshun Mao, Yong Diao
Article Number: 32
Published online on: 06 November 2025

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Unraveling the synergy of inflammation and apoptosis in sepsis-induced acute lung injury: Insights and therapeutic perspectives (Review)

Liwen Zhang, Haoxuan Li, Dongxu Li, Qingqing Dai
Article Number: 31
Published online on: 03 November 2025

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Dihydroalterperylenol from endophytic fungus Alternaria semiverrucosa and its antitumour activity uncovered by transcriptome analysis, molecular docking and molecular dynamics simulations

Mingfei Yang, Yongzhong Lu, Long Han, Zhangjiang He, Jichuan Kang
Article Number: 30
Published online on: 03 November 2025

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[Retracted] Phosphoinositide 3‑kinase/Akt pathway is involved in pingyangmycin‑induced growth inhibition, apoptosis and reduction of invasive potential in EOMA mouse hemangioendothelioma cells

Li-Xia Peng, Ping Zhao, Hong-Sheng Zhao, Er Pan, Bin-Bin Yang, Qin Li
Article Number: 29
Published online on: 03 November 2025

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Tight junction dysfunction and cytoskeletal remodeling in Hirschsprung‑associated enterocolitis: A decade of mechanistic insights and therapeutic prospects (Review)

Shuai Li, Chen Wang, Ling Zhang, Shan Chen, Ying Zhou, Dehua Yang, Kang Li, Yuan Liu, Shuiqing Chi, Yong Wang, Lizhi Li, Shao-Tao Tang
Article Number: 28
Published online on: 03 November 2025

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Involvement of the thioredoxin system in multiple diseases: A focus on mechanisms of action in autophagy and ferroptosis (Review)

Weihua Wang, Yingdong Mou, Dunlin Lu, Shanshan Xu
Article Number: 27
Published online on: 03 November 2025

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MicroRNA‑199a‑3p suppresses non‑small cell lung cancer progression by targeting FTO to enhance m6A‑mediated downregulation of MZF1 and its transcriptional activation of CLDND1

Yuzhen Cui, Xiaoqian Li, Hongkui Zhang, Weiqiang Yuan, Enbo Zhu
Article Number: 26
Published online on: 03 November 2025

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Role of ubiquitin‑proteasome system in preeclampsia (Review)

Chang-Zhu Pei, Xiao-Xing Song, Hao Xu, Kwang-Hyun Baek
Article Number: 25
Published online on: 03 November 2025

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Schisantherin A induces ferroptosis in non‑small cell lung cancer through activation of the YAP/ACSL4/TfR signaling pathway

Wenxiang Zhu, Yeyang Chen, Xiangjian Wu, Xiaoyan Fu, Yongshi He, Yuxia Mo, Qinghua Zhu, Mingwen Tang, Zhiguang Zhai
Article Number: 24
Published online on: 03 November 2025

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The gut‑bone‑cartilage triad: Microbial regulation of the Wnt/β‑catenin signaling pathway in osteoarthritis joint remodeling (Review)

Ruipu Zhang, Liang Zhang, Bin Tian, Yiqun Wang, Xin Kang, Jiang Zheng
Article Number: 23
Published online on: 31 October 2025

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Protective impact of landiolol against acute lung injury following hemorrhagic shock and resuscitation in rats

Risa Sakamoto, Hiroko Shimizu, Ryu Nakamura, Yifu Lu, Yaqiang Li, Emiko Omori, Toru Takahashi, Hiroshi Morimatsu
Article Number: 22
Published online on: 31 October 2025

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Hidden connection: Impact of the gut microbiota on respiratory diseases in children (Review)

Yanhua Han, Yuchao Jia, Lili Chen, Mingyao Zhang
Article Number: 21
Published online on: 29 October 2025

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From renal development to pathology: An analysis of the multilevel role of insulin‑like growth factor 2 (Review)

Yuping Sun, Wenke Hao, Wei Liu, Wenxue Hu
Article Number: 20
Published online on: 29 October 2025

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[Corrigendum] Early anticoagulation therapy for severe burns complicated by inhalation injury in a rabbit model

Zhong-Hua Fu, Guang-Hua Guo, Zhen-Fang Xiong, Xincheng Liao, Ming-Zhuo Liu, Jinhua Luo
Article Number: 19
Published online on: 29 October 2025

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Mucin 2 and unfolded protein response reshape the mucus barrier in inflammatory bowel disease (Review)

Zhiwei Yuan, Zheng Xia, Liyun Ling, Jingzhe Xie, Feng Zhang
Article Number: 18
Published online on: 29 October 2025

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RING finger protein family in leukemia (Review)

Ye Wang, Yue Zhao, Jihong Zhang
Article Number: 17
Published online on: 29 October 2025

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Retinal light perception and biological rhythms: The role of light in sleep and mood from an ophthalmic perspective (Review)

Man Yuan, Hanxiang Liu, Ranjie Zhu, Yuzhen Li, Siyuan Song, Anhuai Yang
Article Number: 16
Published online on: 29 October 2025

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[Retracted] Oxymatrine‑mediated maturation of dendritic cells leads to activation of FOXP3+/CD4+ Treg cells and reversal of cisplatin‑resistance in lung cancer cells

Hui Liu, Manman Zou, Pei Li, Haifeng Wang, Xijun Lin, Jin Ye
Article Number: 15
Published online on: 27 October 2025

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Zinc finger protein 514 promotes esophageal cancer progression by enhancing cell proliferation, migration and invasion

Lin Lv, Xiaoming Sun, Houlu Zhang, Guangxu Wang, Chao Zhang, Haibo Liu, Liangming Zhu
Article Number: 14
Published online on: 24 October 2025

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Effects of zinc carnosine on bone loss in mice with diabetic osteoporosis 

Jingyuan Gao, Hao Yang, Qiangqiang Lian, Yunpeng Hu, Zhou Yang, Lei Xing, Ying Xue, Xiaoli Hou, Faming Tian, Dong Hu
Article Number: 13
Published online on: 24 October 2025

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Rapamycin improves endometriosis‑related infertility involving ovarian senescence via the PPARα/IGFBP2 pathway

Qiongwei Wu, Jiao Fan, Qingjing Sheng, Xiaoying He
Article Number: 12
Published online on: 24 October 2025

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Combining tadalafil and hyperbaric oxygen therapy protects against ovarian ischemia‑reperfusion damage in rats

Mehmet Akif Baktir, Mustafa Ermis, Esra Balcioglu, Betul Yalcin, Enes Karaman, Ahmet Cumaoglu
Article Number: 11
Published online on: 23 October 2025

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Liquid‑liquid phase separation of PHLDB2 promotes oral squamous cell carcinoma metastasis through regulating epithelial mesenchymal transition and PIK3CA expression

Kunyi Chen, Yuhong Wang, Jianing Cui, Qianrui Liu, Xiaoyong Liu, Wenjin Wang, Jinsong Hou
Article Number: 10
Published online on: 22 October 2025

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Mitochondrial gatekeeper in hepatocellular carcinoma: Unraveling the multifaceted roles of VDAC in metabolic reprogramming, apoptosis evasion and therapeutic innovation (Review)

Jie Wang, Yu Liang, Xiaotao Jia, Xinmao Yang, Danning Shi, Yuanchun Wang, Yanfang Pan
Article Number: 9
Published online on: 21 October 2025

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[Retracted] Knockdown of ubiquitin‑specific protease 51 attenuates cisplatin resistance in lung cancer through ubiquitination of zinc‑finger E‑box binding homeobox 1

Feng Zhou, Chunling Du, Donghui Xu, Jinchang Lu, Lei Zhou, Chaomin Wu, Bo Wu, Jianan Huang
Article Number: 8
Published online on: 20 October 2025

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Exploring the role of cytochrome P450 family 1 subfamily B member 1 and quercetin in modulating neuropathic pain after spinal cord injury

Pengyu Zhou, Lu Li, Yu Cao, Jiahao Chen, Chuyin Chen, Xiangsheng Zhang, Jiurong Chen, Yingdong Deng, Ziqiang Lin, Yupei Lai, Suo Wang, Simin Tang, Wenqi Zhang, Peng Sun, Jun Zhou
Article Number: 7
Published online on: 15 October 2025

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R‑loops in hepatocellular carcinoma: Bridging genomic instability and therapeutic opportunity (Review)

Ching-Hua Hsieh, Yueh-Wei Liu, Pei-Chin Chuang
Article Number: 6
Published online on: 15 October 2025

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Role and relevance of exosome-mediated epigenetic regulation in the pathogenesis, diagnosis and treatment of 
cardiovascular diseases (Review)

Yishuo Zhang, Shanshan Zhang, Yijing Li, Wenqi Jin, Liya Zhou, Jing Lu
Article Number: 5
Published online on: 15 October 2025

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PLIN5 deficiency ameliorates metabolic dysfunction‑associated fatty liver disease by inhibiting ferroptosis

Ya Li, Xiaohan Wang, Xuecui Yin, Xiaohui Zhu, Weiqi Cui, Lin Dong, Yu Xia, Ying Wang, Liu Liu, Pengyuan Zheng, Youcai Tang
Article Number: 4
Published online on: 14 October 2025

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Circadian clock genes: Their influence on liver metabolism, disease development and treatment (Review)

Junmin Wang, Mengxing Cao, Shen Li, Wen Pei, Jing Li, Zhen Wang
Article Number: 3
Published online on: 14 October 2025

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MALT1 inhibition by MI‑2 suppresses epithelial‑to‑mesenchymal transition and fibrosis by inactivating the NF‑κB pathway in high glucose‑treated HK‑2 cells

Yating Lan, Jian Ma, Huijun Chen, Chaohong Lan, Na Zhao
Article Number: 2
Published online on: 14 October 2025

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[Retracted] Protective effect of erythropoietin against myocardial injury in rats with sepsis and its underlying mechanisms

Xinliang Zhang, Shimin Dong, Yanjun Qin, Xiaohua Bian
Article Number: 1
Published online on: 14 October 2025

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February-2026 Volume 33 Issue 2

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Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

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Mitophagy and oxidative stress in chronic kidney disease (Review)

Quwu Mushuo, Yihuai Tian, Jianchun Li, Yanqin Qiu, Hui Fan, Qiongdan Hu, Qiong Zhang
Article Number: 61
Published online on: 04 December 2025

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ABCC9 knockdown attenuates isoproterenol‑induced myocardial hypertrophy by inhibiting the PI3K/AKT signaling pathway

Qian Peng, Rui Chang, Linlin Ma, Yanfei Li
Article Number: 60
Published online on: 04 December 2025

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MeCP2 suppresses ferroptosis to drive EMT in retinal pigment epithelial cells: Implications for PVR pathogenesis

Sibei Guo, Yongya Zhang, Xue Li, Xueru Zhao, Yingjuan Liang, Xiaohua Li
Article Number: 59
Published online on: 04 December 2025

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[Corrigendum] Screening for implicated genes in colorectal cancer using whole‑genome gene expression profiling

Long-Ci Sun, Hai-Xin Qian
Article Number: 58
Published online on: 04 December 2025

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Hyperoside prevents osteoporosis by activating the PI3K/AKT signaling pathway to inhibit oxidative stress and promote osteogenesis

Lirong Li, Huaidong Deng, Shabin Zhuan, Boyu Wu, Dawei Xiao
Article Number: 57
Published online on: 03 December 2025

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[Retracted] Interference with Tim‑3 protein expression attenuates the invasion of clear cell renal cell carcinoma and aggravates anoikis

Muming Yu, Bin Lu, Yancun Liu, Ying Me, Lijun Wang, Hui Li
Article Number: 56
Published online on: 01 December 2025

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Acetylshikonin induces ferroptosis via the lipid peroxidation pathway in osteosarcoma cells

Ji-Ying Chen, Guo-Shou Wang, Tsung-Ming Chang, Ju-Fang Liu
Article Number: 55
Published online on: 27 November 2025

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Liver X receptor: A potential target for inflammatory bowel disease and colorectal cancer (Review)

Yingjie Li, Xiaoyan Fu, Meiwen Bai, Jiaqi Zhou, Jiatai Qiu, Hongxia Zhang, Shujuan Liang, Meifang Liu
Article Number: 54
Published online on: 27 November 2025

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lncRNA NEAT1 promotes the proliferation of hemangioma cells by transcriptionally activating β‑catenin via enhancing H3K18 lactylation

Li Yu, Nian Zhou, Xiao-Liang Zhang, Xue-Jing Pang, Lu Xing, Yun-Jing Pu, Li Zhang, Jing-Nan Wu, Hong Shu
Article Number: 53
Published online on: 25 November 2025

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[Retracted] MicroRNA‑206 exerts anti‑oncogenic functions in esophageal squamous cell carcinoma by suppressing the c‑Met/AKT/mTOR pathway

Jin Zhang, Xianen Fa, Qingyong Zhang
Article Number: 52
Published online on: 25 November 2025

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