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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
April 2013 Volume 7 Issue 4

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

Association of the COMT Met158 allele with trait impulsivity in healthy young adults

Márcio Gerhardt Soeiro-De-Souza, Matthew S. Stanford, Danielle Soares Bio, Rodrigo Machado-Vieira, Ricardo Alberto Moreno
Pages: 1067-1072
Published online on: 21 February 2013

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Article Open Access

The role of the mitochondrial calcium uniporter in cerebral ischemia/reperfusion injury in rats involves regulation of mitochondrial energy metabolism

Qin Zhao, Shilei Wang, Yu Li, Peng Wang, Shuhong Li, Yunliang Guo, Ruyong Yao
Pages: 1073-1080
Published online on: 18 February 2013

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Article Open Access

Low‑grade inflammation in the rectum of patients with sporadic irritable bowel syndrome

Magdy El‑Salhy, Doris Gundersen, Jan Gunnar Hatlebakk, Trygve Hausken
Pages: 1081-1085
Published online on: 14 February 2013

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Article

PLAG1 and CYLD do not play a role in the tumorigenesis of adenoid cystic carcinoma

Tsutomu Daa, Itaru Nakamura, Naomi Yada, Shigeki Arakane, Haruto Nishida, Kenji Kashima, Masashi Suzuki, Shigeo Yokoyama
Pages: 1086-1090
Published online on: 06 February 2013

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Article

Sivelestat sodium hydrate reduces radiation-induced lung injury in mice by inhibiting neutrophil elastase

Nobuhiko Yoshikawa, Taisuke Inomata, Yoshikatsu Okada, Taiju Shimbo, Masatsugu Takahashi, Kazuhiko Akita, Yasuo Uesugi, Yoshifumi Narumi
Pages: 1091-1095
Published online on: 08 February 2013

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Article

Therapeutic potential of EGCG on acute renal damage in a rat model of obstructive nephropathy

Ping Zhou, Jin Feng Yu, Cheng Guang Zhao, Feng Xuan Sui, Xu Teng, Yu Bin Wu
Pages: 1096-1102
Published online on: 28 January 2013

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Article

Peiminine ameliorates bleomycin-induced acute lung injury in rats

Hai Guo, Fuzhi Ji, Baorui Liu, Xiaofei Chen, Jingdong He, Jiening Gong
Pages: 1103-1110
Published online on: 07 February 2013

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Article

Participation of CD34-enriched mouse adipose cells in hair morphogenesis

Jing He, Huichuan Duan, Yao Xiong, Wenjie Zhang, Guangdong Zhou, Yilin Cao, Wei Liu
Pages: 1111-1116
Published online on: 05 February 2013

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Article

Altered melatonin secretion and circadian gene expression with increased proinflammatory cytokine expression in early-stage sepsis patients

Cai-Xia Li, Dong-Dong Liang, Guo-Hao Xie, Bao-Li Cheng, Qi-Xing Chen, Shui-Jing Wu, Jun-Lu Wang, William Cho, Xiang-Ming Fang
Pages: 1117-1122
Published online on: 20 February 2013

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Article

Propofol induces rat embryonic neural stem cell apoptosis by activating both extrinsic and intrinsic pathways

Wei-Wei Zou, Hua-Ping Xiao, Miao-Ning Gu, Ke-Xuan Liu, Zhi-Qun Liu
Pages: 1123-1128
Published online on: 29 January 2013

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Article

Evaluation of the proliferation and differentiation behaviors of mesenchymal stem cells with partially converted borate glass containing different amounts of strontium in vitro

Yi Zhu, Yuanming Ouyang, Yi Chang, Congfeng Luo, Jun Xu, Changqing Zhang, Wenhai Huang
Pages: 1129-1136
Published online on: 26 February 2013

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Article

The role of the TLR4 signaling pathway in cognitive deficits following surgery in aged rats

Yi Wang, Huijuan He, Dan Li, Wenjing Zhu, Kaiming Duan, Yuan Le, Yan Liao, Yangwen Ou
Pages: 1137-1142
Published online on: 18 February 2013

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Article

Chordin‑like protein 1 promotes neuronal differentiation by inhibiting bone morphogenetic protein‑4 in neural stem cells

Wei‑Lu Gao, Sheng‑Quan Zhang, Hui Zhang, Bo Wan, Zong‑Sheng Yin
Pages: 1143-1148
Published online on: 06 February 2013

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Article

Growth inhibition effect of peptide P110 plus cisplatin on various cancer cells and xenotransplanted tumors in mice

Ming Li, Jun Wang, Shi‑Yun Tan, Jian‑Hua Chen, Wei Cui, Zhi‑Qiang Chen, Jian Zhang
Pages: 1149-1154
Published online on: 26 February 2013

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Article

The effects of carvedilol on cardiac structural remodeling: The role of endogenous nitric oxide in the activity of carvedilol

Jiangbin Chen, Congxin Huang, Bin Zhang, Qiao Huang, Jing Chen, Lin Xu
Pages: 1155-1158
Published online on: 19 February 2013

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Article

Altered expression of PTCH and HHIP in gastric cancer through their gene promoter methylation: Novel targets for gastric cancer

Yu Song, Ye Tian, Yun Zuo, Jian-Cheng Tu, Yu-Fang Feng, Chen-Jiang Qu
Pages: 1159-1168
Published online on: 21 February 2013

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Article

The role of the serum RANKL/OPG ratio in the healing of intertrochanteric fractures in elderly patients

Xue-Fei Wang, Ya-Kui Zhang, Zhen-Shan Yu, Jun-Lin Zhou
Pages: 1169-1172
Published online on: 21 February 2013

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Article

Mechanism of chronic dietary iron overload‑induced liver damage in mice

Dan Liu, Huan He, Dong Yin, Ailing Que, Lei Tang, Zhangping Liao, Qiren Huang, Ming He
Pages: 1173-1179
Published online on: 08 February 2013

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Article

Inhibitory effect of ARHI on pancreatic cancer cells and NF‑κB activity

Yi‑Qun Hu, Li‑Juan Si, Zhen‑Shi Ye, Zhen‑He Lin, Jing‑Ping Zhou
Pages: 1180-1184
Published online on: 26 February 2013

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Article

Probucol inhibits hydrogen peroxide to induce apoptosis of vascular smooth muscle cells

Lin Sheng, Bo Jiao, Lijuan Shao, Shaojie Bi, Chao Cheng, Jingbo Zhang, Yihao Jiang
Pages: 1185-1190
Published online on: 29 January 2013

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Article

A randomized, open-label clinical trial using optical coherence tomography to compare two sirolimus-eluting stents, one with a biodegradable polymer and the other with a permanent polymer

Feng Tian, Yundai Chen, Changfu Liu, Qinhua Jin, Lian Chen, Zhijun Sun, Hongbin Liu, Jun Guo, Luyue Gai
Pages: 1191-1196
Published online on: 07 February 2013

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Article

Aberrant production of soluble inducible T‑cell co‑stimulator (sICOS) and soluble programmed cell death protein 1 (sPD‑1) in patients with chronic hepatitis C

Dongsheng Wang, Ding'an Zhou, Qin Du, Qi Liang, Qiang Wang, Li Fang, Guangrong Wang, Quming Fan, Beizhong Liu, Jingguo Zhou, Zhong Tang, Hao Wu, Xiaolan Guo, Yanmei Jiao, Guoyuan Zhang
Pages: 1197-1202
Published online on: 19 February 2013

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Article

A high‑fat diet induces obesity and impairs bone acquisition in young male mice

Xiao‑Mei Lu, Hong Zhao, En‑Hua Wang
Pages: 1203-1208
Published online on: 29 January 2013

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Article

Detection of tyrosine‑phosphorylated proteins in hepatocellular carcinoma tissues using a combination of GST‑Nck1‑SH2 pull‑down and two‑dimensional electrophoresis

Fanghua Qiu, Dehong Huang, Hongguang Xiao, Fangying Qiu, Liming Lu, Jing Nie
Pages: 1209-1214
Published online on: 19 February 2013

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Article

Recombinant attenuated Salmonella typhimurium carrying a plasmid co-expressing ENDO-VEGI151 and survivin siRNA inhibits the growth of breast cancer in vivo

Zhe Li, Pei-Hao Yin, Sheng-Sheng Yang, Qian-Yu Li, Tao Chang, Lin Fang, Lin-Xiang Shi, Guo-En Fang
Pages: 1215-1222
Published online on: 05 February 2013

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Article

Sinomenine inhibits the expression of PD‑L1 in the peripheral blood mononuclear cells of mesangial proliferative nephritis patients

Yue Cheng, Furong Li, Daihong Wang, Ying Zhang, Fahuan Yuan, Jingbo Zhang
Pages: 1223-1228
Published online on: 01 February 2013

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Article

Type II, but not type I, cGMP-dependent protein kinase reverses bFGF-induced proliferation and migration of U251 human glioma cells

Zhi-Hong Cao, Yan Tao, Jian-Rong Sang, Yin-Jie Gu, Xiu-Juan Bian, Yong-Chang Chen
Pages: 1229-1234
Published online on: 11 February 2013

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Article

H2O2 inhibits the growth of human pulmonary fibroblast cells by inducing cell death, GSH depletion and G1 phase arrest

Woo Hyun Park
Pages: 1235-1240
Published online on: 01 February 2013

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Article Open Access

Reduced chromogranin A cell density in the ileum of patients with irritable bowel syndrome

Magdy El-Salhy, Ingvild Haukaas Wendelbo, Doris Gundersen
Pages: 1241-1244
Published online on: 19 February 2013

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Article

Gene expression levels of cytokines in peripheral blood mononuclear cells from patients with pulmonary embolism

Wei Lv, Qianglin Duan, Lemin Wang, Zhu Gong, Fan Yang, Yanli Song
Pages: 1245-1250
Published online on: 26 February 2013

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Article

shRNAs targeting high‑mobility group box-1 inhibit E-selectin expression via homeobox A9 in human umbilical vein endothelial cells

Xiao-Juan Zhang, Zheng-Gang Luan, Xiao-Chun Ma
Pages: 1251-1256
Published online on: 07 February 2013

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Article

hcrcn81 is upregulated by rapamycin treatment in human colorectal adenocarcinoma cells

Xiaoxia Wen, Lei Dong, Jianjun Zhu, Yao Chen
Pages: 1257-1260
Published online on: 08 February 2013

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Article

Relevance of IL-6 and MMP-9 to cerebral arteriovenous malformation and hemorrhage

Xiong Li, Rong Wang, Xuejiang Wang, Xiaowei Xue, Duan Ran, Shuo Wang
Pages: 1261-1266
Published online on: 20 February 2013

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Article

The effect of a proton pump inhibitor on bone metabolism in ovariectomized rats

Moon Kyung Joo, Jong-Jae Park, Beom Jae Lee, Ji Hoon Kim, Jong Eun Yeon, Jae Seon Kim, Kwan Soo Byun, Young-Tae Bak
Pages: 1267-1272
Published online on: 19 February 2013

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Article

The expression of NMDA receptor and pCREB in the visual cortex of monocularly‑deprived rats

Xiaonan Sun, Jinsong Zhang
Pages: 1273-1277
Published online on: 01 February 2013

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Article

Hypoglycemic effects of glabridin, a polyphenolic flavonoid from licorice, in an animal model of diabetes mellitus

Feihua Wu, Zhigui Jin, Jian Jin
Pages: 1278-1282
Published online on: 19 February 2013

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Article

Inhibition of proliferation of estrogen receptor‑positive MCF‑7 human breast cancer cells by tamoxifen through c‑Jun transcription factors

Yan Xu, Shi‑Tao Zou, Ran Zhu, Wei Li, Chun‑Wei Gu, Shao‑Hua Wei, Jia‑Ming Xie, Hao‑Rong Wu
Pages: 1283-1287
Published online on: 05 February 2013

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Article

Antiproliferative activity of Alpinia officinarum extract in the human breast cancer cell line MCF-7

Sungho Ghil
Pages: 1288-1292
Published online on: 05 February 2013

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Article

Oxymatrine protects against myocardial injury via inhibition of JAK2/STAT3 signaling in rat septic shock

Minghao Zhang, Xiuyu Wang, Xiumei Wang, Xiaolin Hou, Peng Teng, Yideng Jiang, Linna Zhang, Xiaoling Yang, Jue Tian, Guizhong Li, Jun Cao, Hua Xu, Yunhong Li, Yin Wang
Pages: 1293-1299
Published online on: 08 February 2013

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Article

Role of TRPV1 and P2X receptors in the activation of lung vagal C-fiber afferents by inhaled cigarette smoke in rats

Wen-Hui Weng, Chun-Chun Hsu, Ling-Ling Chiang, Yi-Jiun Peter Lin, You Shuei Lin, Chien-Ling Su
Pages: 1300-1304
Published online on: 30 January 2013

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Article

Human endogenous retrovirus-H insertion screening

Mehrab Guliyev, Sibel Yilmaz, Kaniye Sahin, Sevgi Marakli, Nermin Gozukirmizi
Pages: 1305-1309
Published online on: 28 January 2013

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Article

Association between the endothelial nitric oxide synthase gene Glu298Asp polymorphism and coronary heart disease: A meta‑analysis of 39 case‑control studies

Guo‑Xiang Tian, Xian‑Tao Zeng, Xiao‑Bing Wang, Ling Zhang, Wei Zhang, Wan‑Lin Wei
Pages: 1310-1318
Published online on: 30 January 2013

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Article

Effect of a BK viruria reaction detected by qualitative polymerase chain reaction on the renal function of kidney transplant recipients

Ming‑Chang Hsieh, Ching‑Wen Hung, Hui‑Ling Chiou, Shun‑Fa Yang
Pages: 1319-1323
Published online on: 21 February 2013

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Article

Effects of the downregulation of SnoN expression on HepG2 cell proliferation and apoptosis

Wenqi Wang, Changhong Liu, Yiguo Wang, Lili Cao
Pages: 1324-1328
Published online on: 26 February 2013

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Article

IL-22 exacerbates the severity of CVB3-induced acute viral myocarditis in IL-17A-deficient mice

Qing Kong, Yimin Xue, Weifeng Wu, Fan Yang, Yanli Liu, Mengsha Gao, Wenyin Lai, Xiaofen Pan
Pages: 1329-1335
Published online on: 18 February 2013

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Article

Pioglitazone inhibits high glucose‑induced synthesis of extracellular matrix by NF‑κB and AP‑1 pathways in rat peritoneal mesothelial cells

Guangyu Zhou, Xuesong Su, Jianfei Ma, Lining Wang, Detian Li
Pages: 1336-1342
Published online on: 06 February 2013

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Article

Allitridin inhibits human cytomegalovirus replication in vitro

Ju Zhang, Hui Wang, Zhi-Dan Xiang, Sai-Nan Shu, Feng Fang
Pages: 1343-1349
Published online on: 19 February 2013

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Article

Effect of the PA‑MSHA vaccine on septic serum‑induced inflammatory response

Xiang‑Feng Liu, Li Wang, Yi Qu, De-Wu Zhong, Xiong-Ying Miao, Hong‑Liang Yao
Pages: 1350-1354
Published online on: 21 February 2013

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Article

Validation study of 131I‑RRL: Assessment of biodistribution, SPECT imaging and radiation dosimetry in mice

Qian Zhao, Ping Yan, Lei Yin, Ling Li, Xue Qi Chen, Chao Ma, Rong Fu Wang
Pages: 1355-1360
Published online on: 22 February 2013

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Article

Changes in serum IGF‑1 level and tumor VEGF expression in mice with colorectal cancer under hyperglycemic conditions

Hong Cao, Chunhui Jin, Defang Huang, Chao Liu, Daoqi Sun, Cheng Tan, Xiaoming Zhu, Yajun Fei
Pages: 1361-1365
Published online on: 26 February 2013

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Correction Open Access

[Corrigendum] Influence of lactoferrin in preventing preterm delivery: A pilot study

Giuliana Giunta, Lorena Giuffrida, Katia Mangano, Paolo Fagone, Antonio Cianci
Pages: 1366-1366
Published online on: 27 February 2013

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Journal Cover
February-2026 Volume 33 Issue 2

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

ISX promotes tumor migration and invasion in lung cancer by upregulating COL1A1 in vitro

Yihe Ma, Ye Chen, Yuhui Liang, Yun Huang, Miao Gong, Lifeng Tian, Xiaojun Xiao, Jingyan Liu, Qinmiao Huang
Article Number: 77
Published online on: 31 December 2025

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Article Open Access

Role and mechanism of miR‑222‑5p in endothelial cell apoptosis

Shimeng Wang, Boxin Zhao, Ying Cui, Lin Gui, Jingyao Fan, Lijuan Huang
Article Number: 76
Published online on: 31 December 2025

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Expression of Concern Open Access

[Expression of Concern] MicroRNA-29c inhibits proliferation and promotes apoptosis in non-small cell lung cancer cells by targeting VEGFA

Shijuan Zhan, Chunfeng Wang, Fangqing Yin
Article Number: 75
Published online on: 22 December 2025

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Article Open Access

Melatonin induces autophagy in neuroblastoma by alleviating Pak2‑mediated endoplasmic reticulum stress

Qian-Qi Qiu, Na Zhang, Ying-Yi Xu, Jing-Wen Qin, Gao-Feng Yu, Xing-Rong Song
Article Number: 74
Published online on: 22 December 2025

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Article Open Access

ST3Gal1 modulates intestinal barrier function and impacts human ulcerative colitis

Yin Tian, Yun Liu, Yangyang Shang, Lijian Ran, Li Liu, Rongquan Wang, Jun Ye
Article Number: 73
Published online on: 18 December 2025

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Article Open Access

Mechanistic study of miR‑369‑3p in regulating the Wnt/β‑catenin signaling pathway via targeting SPTBN1 in inflammatory response and bone destruction of rheumatoid arthritis

Aihong Wu, Yuan Wang, Feifei Liu, Zhoufang Cao, Shuhui Du, Mengyu Sun
Article Number: 72
Published online on: 18 December 2025

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Article Open Access

CACNB1 alleviates mepivacaine‑induced myocardial ischemia/reperfusion injury by promoting Nrf2 nuclear translocation

Qingbo Shao, Ji Zhang, Huaying Wang
Article Number: 71
Published online on: 17 December 2025

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Expression of Concern Open Access

[Expression of Concern] Effects of cullin 4B on the proliferation and invasion of human gastric cancer cells

Feng He, Xiu-Mei Cheng, Wen-Long Gu
Article Number: 70
Published online on: 17 December 2025

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Article Open Access

Aggravated effects of human parvovirus B19 NS1 protein on bleomycin‑induced pulmonary fibrosis

Tsai-Ching Hsu, Chih-Chen Tzang, Chia-Wei Kuo, Zhi-Han Wen, Der-Yuan Chen, Bor-Show Tzang
Article Number: 69
Published online on: 16 December 2025

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Review Open Access

Advances regarding the mechanism of endoplasmic reticulum stress in diabetic kidney disease and pharmacological interventions (Review)

Pai Zhang, Yabin Cui, Chunyan Liu, Chengji Cui, Shoulin Zhang, Yue Zhang, Fan Li
Article Number: 68
Published online on: 16 December 2025

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Retraction Open Access

[Retracted] N‑Myc downstream‑regulated gene 2 suppresses the proliferation of T24 human bladder cancer cells via induction of oncosis

Jie Huang, Zhou Wu, Guangxiu Wang, Yingxian Cai, Minshan Cai, Yaozhang Li
Article Number: 67
Published online on: 15 December 2025

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Review Open Access

Deciphering epigenetic regulation in cardiac developmental toxicity: Mechanisms and implications (Review)

Ziling Qin, Ranran Chen, Dianrong Song
Article Number: 66
Published online on: 11 December 2025

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Review Open Access

Gut microbiota as a multifaceted modulator of prostate cancer: Mechanistic insights, therapeutic opportunities and clinical challenges (Review)

Zhenming Hao, Yongqiang Xie, Ru Zhang, Hui Sang, Luxi Li, Yulin Liu, Jinbo Hu, Jijun Wang, Keqiang Chai, Qiang Zhao
Article Number: 65
Published online on: 11 December 2025

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Expression of Concern Open Access

[Expression of Concern] lncRNA FLVCR1‑AS1 drives colorectal cancer progression via modulation of the miR‑381/RAP2A axis

Yi Han, Xiaoyan Wang, Enqiang Mao, Boyong Shen, Liang Huang
Article Number: 64
Published online on: 10 December 2025

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Influence and treatment of insulin receptor substrate/PI3K/Akt‑mediated insulin resistance in diabetes mellitus (Review)

Weikang Tang, Huixia Liu, Xuan Li, Siyao Deng, Changyu Gao
Article Number: 63
Published online on: 09 December 2025

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Retraction Open Access

[Retracted] Long non‑coding RNA ANRIL knockdown suppresses apoptosis and pro‑inflammatory cytokines while enhancing neurite outgrowth via binding microRNA‑125a in a cellular model of Alzheimer’s disease

Bingling Zhou, Lijuan Li, Xin Qiu, Jiashun Wu, Lei Xu, Wei Shao
Article Number: 62
Published online on: 08 December 2025

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Mitophagy and oxidative stress in chronic kidney disease (Review)

Quwu Mushuo, Yihuai Tian, Jianchun Li, Yanqin Qiu, Hui Fan, Qiongdan Hu, Qiong Zhang
Article Number: 61
Published online on: 04 December 2025

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Article Open Access

ABCC9 knockdown attenuates isoproterenol‑induced myocardial hypertrophy by inhibiting the PI3K/AKT signaling pathway

Qian Peng, Rui Chang, Linlin Ma, Yanfei Li
Article Number: 60
Published online on: 04 December 2025

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Article

MeCP2 suppresses ferroptosis to drive EMT in retinal pigment epithelial cells: Implications for PVR pathogenesis

Sibei Guo, Yongya Zhang, Xue Li, Xueru Zhao, Yingjuan Liang, Xiaohua Li
Article Number: 59
Published online on: 04 December 2025

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Correction Open Access

[Corrigendum] Screening for implicated genes in colorectal cancer using whole‑genome gene expression profiling

Long-Ci Sun, Hai-Xin Qian
Article Number: 58
Published online on: 04 December 2025

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Article Open Access

Hyperoside prevents osteoporosis by activating the PI3K/AKT signaling pathway to inhibit oxidative stress and promote osteogenesis

Lirong Li, Huaidong Deng, Shabin Zhuan, Boyu Wu, Dawei Xiao
Article Number: 57
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Interference with Tim‑3 protein expression attenuates the invasion of clear cell renal cell carcinoma and aggravates anoikis

Muming Yu, Bin Lu, Yancun Liu, Ying Me, Lijun Wang, Hui Li
Article Number: 56
Published online on: 01 December 2025

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Article Open Access

Acetylshikonin induces ferroptosis via the lipid peroxidation pathway in osteosarcoma cells

Ji-Ying Chen, Guo-Shou Wang, Tsung-Ming Chang, Ju-Fang Liu
Article Number: 55
Published online on: 27 November 2025

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Liver X receptor: A potential target for inflammatory bowel disease and colorectal cancer (Review)

Yingjie Li, Xiaoyan Fu, Meiwen Bai, Jiaqi Zhou, Jiatai Qiu, Hongxia Zhang, Shujuan Liang, Meifang Liu
Article Number: 54
Published online on: 27 November 2025

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Article Open Access

lncRNA NEAT1 promotes the proliferation of hemangioma cells by transcriptionally activating β‑catenin via enhancing H3K18 lactylation

Li Yu, Nian Zhou, Xiao-Liang Zhang, Xue-Jing Pang, Lu Xing, Yun-Jing Pu, Li Zhang, Jing-Nan Wu, Hong Shu
Article Number: 53
Published online on: 25 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑206 exerts anti‑oncogenic functions in esophageal squamous cell carcinoma by suppressing the c‑Met/AKT/mTOR pathway

Jin Zhang, Xianen Fa, Qingyong Zhang
Article Number: 52
Published online on: 25 November 2025

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March-2026 Volume 33 Issue 3

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Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Advances in the mechanisms of the NLRP3 inflammasome in sepsis‑induced cardiomyopathy and targeted therapeutic studies 
(Review)

Yifei Chen, Zhaohui Zhang, Gaosheng Zhou
Article Number: 98
Published online on: 22 January 2026

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HMGN2 induces pyroptosis in tumour cells by modulating the STT3B/PD‑L1/caspase‑1/GSDMD axis

Wenwen Han, Hongli Chen, Bomiao Cui, Jiao Chen, Ping Zhang, Yun Feng
Article Number: 97
Published online on: 22 January 2026

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Naringin ameliorates intestinal injury in ulcerative colitis model mice by modulating the JAK2/STAT3 signaling pathway

Miaomiao Wu, Yating An, Yongmin Li, Wei He, Ying Wang, Yaqi Wang, Caixia Wu
Article Number: 96
Published online on: 22 January 2026

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PDX1 in human cancers: Molecular mechanisms, dual roles and clinical implications (Review)

Chen Zhou, Yifei Wang, Jie Zhao, Yantao Yang, Yuhang Yuan, Xiaochen Hou, Yu Tang, Lianhua Ye
Article Number: 95
Published online on: 22 January 2026

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Retraction Open Access

[Retracted] Autophagy flux inhibition mediated by celastrol sensitized lung cancer cells to TRAIL‑induced apoptosis via regulation of mitochondrial transmembrane potential and reactive oxygen species

Uddin Md Nazim, Honghua Yin, Sang-Youel Park
Article Number: 94
Published online on: 19 January 2026

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Converting ‘cold’ to ‘hot’ hepatocellular carcinoma for improved immunotherapy (Review)

Ching-Hua Hsieh, Pei-Chin Chuang
Article Number: 93
Published online on: 15 January 2026

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Pathological mechanism of ferroptosis in a rat model of α‑naphthyl isothiocyanate‑induced chronic cholestasis

Zhen Guo, Jiaxuan Wang, Yiwen Wang, Xinzhu Liu, Yubing Xia, Ping Liu, Li Qi, Jia Liu, Xiaoning Wang
Article Number: 92
Published online on: 14 January 2026

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Correction Open Access

[Corrigendum] Role of hypoxia‑inducible factor‑1α and CD146 in epidermal growth factor receptor‑mediated angiogenesis in salivary gland adenoid cystic carcinom

Wei-Ming Wang, Zhi-Li Zhao, Wen-Feng Zhang, Yi-Fang Zhao, Lu Zhang, Zhi-Jun Sun
Article Number: 91
Published online on: 13 January 2026

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Klebsiella pneumoniae and pyogenic liver abscess: Emerging clinical threats, virulence mechanisms and therapeutic strategies (Review)

Gulam Mustafa Hasan, Taj Mohammad, Sobia Zaidi, Anas Shamsi, Sukhwinder Singh Sohal, Md. Imtaiyaz Hassan
Article Number: 90
Published online on: 13 January 2026

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Article Open Access

Collagen III regulates the termination of liver regeneration by suppressing hepatocyte proliferation and promoting functional recovery

Haiyang Peng, Zhiyong Chen, Qiwei Zhang, Yuezhou Zhang, Peng Yang, Jianping Gong, Andong Zhao
Article Number: 89
Published online on: 13 January 2026

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Review Open Access

Application of extracellular vesicles in the diagnosis and treatment of chronic obstructive pulmonary disease (Review)

Yixin Zhang, Tong Ren, Jianbo Xue, Yan Yu, Xianqiang Zhou, Xiaoyi Hu, Wenyi Yu, Zhancheng Gao, Cuiling Feng
Article Number: 88
Published online on: 13 January 2026

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Cigarette smoke combined with Klebsiella pneumoniae induce damage to the air‑blood barrier in chronic obstructive pulmonary disease rats via the MAPK/NF‑κB/IκBα pathway

Yange Tian, Kexin Xu, Ruilong Lu, Kangchen Li, Xuejie Shao, Yixi Liao, Yakun Zhao, Zhiguang Qiu, Haoran Dong, Xuefang Liu
Article Number: 87
Published online on: 12 January 2026

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Retraction Open Access

[Retracted] 8‑bromo‑7‑methoxychrysin induces apoptosis by regulating Akt/FOXO3a pathway in cisplatin‑sensitive and resistant ovarian cancer cells

Qing Ding, Yi Chen, Qing Zhang, Yanling Guo, Zhi Huang, Liqing Dai, Sudan Cao
Article Number: 86
Published online on: 12 January 2026

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Article Open Access

Anxiety‑induced overactive bladder: The role of oxidative stress and NF‑κB signaling pathway with Hsp90 as a potential biomarker

Zhipeng Zhou, Lina Xu, Han Wu, Huaishan Hong
Article Number: 85
Published online on: 12 January 2026

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Article Open Access

Echinacoside alleviates asthenozoospermia by upregulating Sox5‑mediated transcriptional activation of the CatSper gene

Zi-Run Jin, Yong-Wei Huo, Bo-Heng Liu, Hong Tian, Shuo Yuan, Yue Tian, Ke Xi, Jie Cai, Hui Jiang, Yong Jiang, Guo-Gang Xing
Article Number: 84
Published online on: 12 January 2026

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Article Open Access

Artemisiae Scopariae Herba (Yinchen) suppresses ferroptosis in mice with osteoporosis via the Nrf2/Slc7a11/Gpx4 pathway

Pei Li, Xinyu Wan, Wenjie Li, Ding Cheng, Ying Yang, Yuhan Wang, Ruyuan Zhu, Yanjing Chen, Haixia Liu, Zhiguo Zhang
Article Number: 83
Published online on: 12 January 2026

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Review Open Access

Prolyl hydroxylase domain proteins: Localization, regulation, function and their role in erythropoiesis (Review)

Yan Hou, Zhao-Hua Zhang, Wen-Qian Li, Guo-Xiong Han, Kuo Shen, You-Bang Xie
Article Number: 82
Published online on: 12 January 2026

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Review Open Access

Therapeutic potential of saponins for allergic rhinitis: Molecular mechanisms and clinical perspectives (Review)

Bing-Yu Liang, Zi-Yue Fu, Fen-Fen Li, Ping-Ting Zhou, Zi-Hui Xie, Ke Han, Yan-Xun Han, Shan-Wen Chen, Yi Zhao, Hai-Feng Pan, Ye-Hai Liu, Yu-Chen Liu
Article Number: 81
Published online on: 07 January 2026

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Interleukin‑6 and ischemic stroke: From mechanisms to clinical prospects (Review)

Xinyue Wang, Xiaohang Zhang, Jianing Lin, Ping Lin
Article Number: 80
Published online on: 05 January 2026

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Article Open Access

Preliminary exploration of the putative function of SF3A2 in clear cell renal cell carcinoma

Ru Chen, Jie Xu
Article Number: 79
Published online on: 05 January 2026

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Retraction Open Access

[Retracted] TIPE‑2 suppresses growth and aggressiveness of hepatocellular carcinoma cells through downregulation of the phosphoinositide 3‑kinase/AKT signaling pathway

Lin Wang, Chen Chen, Shuzhi Feng, Jianli Tian
Article Number: 78
Published online on: 05 January 2026

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