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Molecular Medicine Reports
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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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June-2014 Volume 9 Issue 6

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Association of glycogen synthase kinase‑3β with Parkinson's disease (Review)

Da‑Wei Li, Zhi‑Qiang Liu, Wei Chen, Min Yao, Guang‑Ren Li
Pages: 2043-2050
Published online on: 28 March 2014

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Review

Use of regulators and inhibitors of Pim-1, a serine/threonine kinase, for tumour therapy (Review)

Chen Liang, Ying-Yi Li
Pages: 2051-2060
Published online on: 11 April 2014

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Article Open Access

Effect of gender differences on the regulation of renal ischemia‑reperfusion‑induced inflammation in mice

Kyung Pyo Kang, Jung Eun Lee, Ae Sin Lee, Yu Jin Jung, Dal Kim, Sik Lee, Hong Pil Hwang, Won Kim, Sung Kwang Park
Pages: 2061-2068
Published online on: 28 March 2014

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Article Open Access

Enhanced efficacy of combination therapy with adeno‑associated virus-delivered pigment epithelium-derived factor and cisplatin in a mouse model of Lewis lung carcinoma

Sha-Sha He, Qin-Jie Wu, Chang Yang Gong, Shun-Tao Luo, Shuang Zhang, Meng Li, Lian Lu, Yu-Quan Wei, Li Yang
Pages: 2069-2076
Published online on: 04 April 2014

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Article Open Access

Dual role of acetaminophen in promoting hepatoma cell apoptosis and kidney fibroblast proliferation

Yung‑Luen Yu, Giou‑Teng Yiang, Pei‑Lun Chou, Hsu‑Hung Tseng, Tsai‑Kun Wu, Yu‑Ting Hung, Pei‑Shiuan Lin, Shu‑Yu Lin, Hsiao‑Chun Liu, Wei‑Jung Chang, Chyou‑Wei Wei
Pages: 2077-2084
Published online on: 28 March 2014

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Article

MicroRNA‑518d regulates PPARα protein expression in the placentas of females with gestational diabetes mellitus

Chun Zhao, Ting Zhang, Zhonghua Shi, Hongjuan Ding, Xiufeng Ling
Pages: 2085-2090
Published online on: 17 March 2014

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Article

Enhanced p62 expression triggers concomitant autophagy and apoptosis in a rat chronic spinal cord compression model

Zhi Chen, Qingge Fu, Baoliang Shen, Xuan Huang, Kun Wang, Ping He, Fengning Li, Fan Zhang, Hongxing Shen
Pages: 2091-2096
Published online on: 08 April 2014

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Article Open Access

Endogenous n-3 polyunsaturated fatty acids protect against imiquimod-induced psoriasis-like inflammation via the IL-17/IL-23 axis

Si Qin, Ju Wen, Xiao-Chun Bai, Tian-Yu Chen, Rong-Chang Zheng, Gui‑Bin Zhou, Jing Ma, Jie-Ying Feng, Bi-Ling Zhong, Yi-Ming Li
Pages: 2097-2104
Published online on: 09 April 2014

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Article Open Access

Polymeric immunoglobulin receptor expression is correlated with poor prognosis in patients with osteosarcoma

Xuanwei Wang, Jingyu Du, Pengcheng Gu, Rilong Jin, Xiangjin Lin
Pages: 2105-2110
Published online on: 02 April 2014

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Article Open Access

Identification of differentially expressed genes involved in transient regeneration of the neonatal C57BL/6J mouse heart by digital gene expression profiling

Ming Liu, Jin‑Gai Zhu, Zhang‑Bin Yu, Gui‑Xian Song, Ya‑Hui Shen, Yao‑Qiu Liu, Chun Zhu, Ling‑Mei Qian
Pages: 2111-2116
Published online on: 02 April 2014

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Article Open Access

Enrichment and characterization of cancer stem‑like cells from a cervical cancer cell line

Li Wang, Huijie Guo, Caiyu Lin, Liuqi Yang, Xiujie Wang
Pages: 2117-2123
Published online on: 20 March 2014

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Article Open Access

Preconditioned hyperbaric oxygenation protects skin flap grafts in rats against ischemia/reperfusion injury

Nan Kang, Yong Hai, Fang Liang, Chun‑Jin Gao, Xue‑Hua Liu
Pages: 2124-2130
Published online on: 24 March 2014

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Article Open Access

Astragaloside Ⅳ reduces the expression level of P‑glycoprotein in multidrug‑resistant human hepatic cancer cell lines

Pei‑Pei Wang, Du‑Juan Xu, Can Huang, Wei‑Ping Wang, Wen‑Ke Xu
Pages: 2131-2137
Published online on: 27 March 2014

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Article Open Access

Correlation of CTGF gene promoter methylation with CTGF expression in type 2 diabetes mellitus with or without nephropathy

Hao Zhang, Xu Cai, Bin Yi, Jing Huang, Jianwen Wang, Jian Sun
Pages: 2138-2144
Published online on: 24 March 2014

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Article Open Access

β-catenin is overexpressed in hepatic fibrosis and blockage of Wnt/β-catenin signaling inhibits hepatic stellate cell activation

Wen-Song Ge, Yao-Jun Wang, Jian-Xin Wu, Jian-Gao Fan, Ying-Wei Chen, Liang Zhu
Pages: 2145-2151
Published online on: 01 April 2014

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Article Open Access

Highly efficient release of simvastatin from simvastatin‑loaded calcium sulphate scaffolds enhances segmental bone regeneration in rabbits

Xin Huang, Zhongming Huang, Weixu Li
Pages: 2152-2158
Published online on: 01 April 2014

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Article

Invadopodia are essential in transurothelial invasion during the muscle invasion of bladder cancer cells

Kengo Imanishi, Mihoko Sutoh Yoneyama, Shingo Hatakeyama, Hayato Yamamoto, Takuya Koie, Hisao Saitoh, Kanemitsu Yamaya, Tomihisa Funyu, Toshiya Nakamura, Chikara Ohyama, Shigeru Tsuboi
Pages: 2159-2165
Published online on: 03 April 2014

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Article Open Access

Autophagy in human articular chondrocytes is cytoprotective following glucocorticoid stimulation

Ning Liu, Wenbo Wang, Zhe Zhao, Tao Zhang, Yuwen Song
Pages: 2166-2172
Published online on: 01 April 2014

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Article Open Access

Gene silencing of NOB1 by lentivirus suppresses growth and migration of human osteosarcoma cells Corrigendum in /10.3892/mmr.2022.12909

Bingpeng Chen, Jingjing Liu, Dankai Wu, Yanguo Qin, Chuangang Peng, Chen Li, Jincheng Wang
Pages: 2173-2179
Published online on: 04 April 2014

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Article Open Access

Angiotensin-(1-7) and angiotensin Ⅱ induce the transdifferentiation of human endometrial epithelial cells in vitro

Tieying Shan, Lei Zhang, Chunfang Zhao, Wei Chen, Yanan Zhang, Guiying Li
Pages: 2180-2186
Published online on: 09 April 2014

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Article

A novel mild variant of osteogenesis imperfecta type I caused by a Gly1088Glu mutation in COL1A1

Xin‑Yi Xia, Wei‑Wei Li, Na Li, Qiu‑Yue Wu, Ying‑Xia Cui, Xiao‑Jun Li
Pages: 2187-2190
Published online on: 28 March 2014

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Article

Spectroscopic investigations of the interaction of the anti‑hypertension drug valsartan with human serum albumin

Jian Jing, Xin Qu, Zhi Tu, Chenhoo Zheng, Zhicheng Zheng
Pages: 2191-2196
Published online on: 09 April 2014

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Article

Resveratrol protects primary cortical neuron cultures from transient oxygen‑glucose deprivation by inhibiting MMP‑9

Dakuan Gao, Tao Huang, Xiaofan Jiang, Shijie Hu, Lei Zhang, Zhou Fei
Pages: 2197-2204
Published online on: 28 March 2014

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Article Open Access

Module-based functional pathway enrichment analysis of a protein‑protein interaction network to study the effects of intestinal microbiota depletion in mice

Zhen‑Yi Jia, Yang Xia, Danian Tong, Jing Yao, Hong‑Qi Chen, Jun Yang
Pages: 2205-2212
Published online on: 09 April 2014

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Article

microRNA‑21 protects against ischemia‑reperfusion and hypoxia‑reperfusion‑induced cardiocyte apoptosis via the phosphatase and tensin homolog/Akt‑dependent mechanism

Qiong Yang, Kan Yang, Anying Li
Pages: 2213-2220
Published online on: 24 March 2014

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Article

Protective effect of fluvastatin on influenza virus infection

Jing Peng, Dingmei Zhang, Yu Ma, Guoling Wang, Zhongmin Guo, Jiahai Lu
Pages: 2221-2226
Published online on: 27 March 2014

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Article

Nicorandil attenuates endothelial VCAM‑1 expression via thioredoxin production in diabetic rats induced by streptozotocin

Lihua Liu, Yun Liu, Benling Qi, Qinqin Wu, Yuanyuan Li, Zhaohui Wang
Pages: 2227-2232
Published online on: 24 March 2014

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Article

Receptors of the Notch signaling pathway are associated with hemorrhage of brain arteriovenous malformations

Shu Li, Rong Wang, Yajie Wang, Haowen Li, Jian Zheng, Ran Duan, Jizong Zhao
Pages: 2233-2238
Published online on: 18 March 2014

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Article

Construction and characterization of a Vibrio cholerae serogroup O139 vaccine candidate by genetic engineering

Cancan Cheng, Yanyan Zhou, Biao Kan, Qian Wang, Yongyu Rui
Pages: 2239-2244
Published online on: 24 March 2014

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Article

Exogenous IL-10 induces corneal transplantation immune tolerance by a mechanism associated with the altered Th1/Th2 cytokine ratio and the increased expression of TGF-β

Bing Li, Lihua Tian, Yumei Diao, Xue Li, Liying Zhao, Xuefeng Wang
Pages: 2245-2250
Published online on: 27 March 2014

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Article

Effect of metformin on apoptosis, cell cycle arrest migration and invasion of A498 cells

Zhiqing Fang, Xiulian Xu, Zunlin Zhou, Zhonghua Xu, Zhaoxu Liu
Pages: 2251-2256
Published online on: 31 March 2014

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Article

Genetic alterations following ionizing radiation in human ovarian cancer‑derived endothelial cells

Ting Liu, Xuelian Du, Xiugui Sheng
Pages: 2257-2264
Published online on: 31 March 2014

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Article

Paris saponin I induces apoptosis via increasing the Bax/Bcl‑2 ratio and caspase‑3 expression in gefitinib‑resistant non‑small cell lung cancer in vitro and in vivo

Hao Jiang, Peng‑Jun Zhao, Dan Su, Jianguo Feng, Sheng‑Lin Ma
Pages: 2265-2272
Published online on: 02 April 2014

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Article

Safety assessment of So‑cheong‑ryong‑tang: Subchronic toxicity study in Crl:CD Sprague Dawley rats

Mee‑Young Lee, Chang‑Seob Seo, Shin‑Woo Cha, Hyeun‑Kyoo Shin
Pages: 2273-2282
Published online on: 03 April 2014

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Article

Novel tumor-suppressor gene epidermal growth factor‑containing fibulin‑like extracellular matrix protein 1 is epigenetically silenced and associated with invasion and metastasis in human gastric cancer

Xin-Jiang Zhu, Jian Liu, Xiao-Yang Xu, Chun-Dong Zhang, Dong-Qiu Dai
Pages: 2283-2292
Published online on: 09 April 2014

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Article

Intraperitoneal administration of the globular adiponectin gene ameliorates diabetic nephropathy in Wistar rats

Fang Yuan, Ying‑Hong Liu, Fu‑You Liu, You‑Ming Peng, Jun‑Wei Tian
Pages: 2293-2300
Published online on: 09 April 2014

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Article

Induced production of anti-etanercept antibody in collagen-induced arthritis

Hyoju Yi, Juryun Kim, Hyerin Jung, Yeri Alice Rim, Youngkyun Kim, Seung Min Jung, Sung-Hwan Park, Ji Hyeon Ju
Pages: 2301-2308
Published online on: 09 April 2014

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Article

Autophagy may protect MC3T3-E1 cells from fluoride-induced apoptosis

Min Wei, Dongmei Duan, Yujie Liu, Zhigang Wang, Zhongli Li
Pages: 2309-2315
Published online on: 28 March 2014

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Article

Signal tranducers and activators of transcription: Expression and function in anti‑neutrophil cytoplasmic antibody‑associated vasculitis

Benjamin Wilde, André Hoerning, Andreas Kribben, Oliver Witzke, Sebastian Dolff
Pages: 2316-2320
Published online on: 20 March 2014

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Article

Thoc1 inhibits cell growth via induction of cell cycle arrest and apoptosis in lung cancer cells

Jianmei Wan, Shitao Zou, Mengshang Hu, Ran Zhu, Jiaying Xu, Yang Jiao, Saijun Fan
Pages: 2321-2327
Published online on: 28 March 2014

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Article

Evaluation of the effect of static magnetic fields combined with human hepatocyte growth factor on human satellite cell cultures

Richard Birk, Ulrich Sommer, Anne Faber, Christoph Aderhold, Johannes  D. Schulz, Karl Hörmann, Ulrich Reinhart Goessler, Jens Stern-Straeter
Pages: 2328-2334
Published online on: 28 March 2014

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Article

Expression of hormone receptors, Bcl‑2, Cox‑2 and Ki67 in benign endometrial polyps and their association with obesity

Anderson Pinheiro, Armando Antunes, Liliana Andrade, Louise De Brot, Aarão Mendes Pinto‑Neto, Lúcia Costa‑Paiva
Pages: 2335-2341
Published online on: 09 April 2014

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Article

Screening of hepatocyte proteins binding with the middle surface protein of the hepatitis B virus by the yeast two‑hybrid system

Zhiqun Li, Enqiang Linghu, Jun Cheng
Pages: 2342-2346
Published online on: 24 March 2014

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Article

TPX2 regulates tumor growth in human cervical carcinoma cells

Peiyue Jiang, Kexin Shen, Xuerui Wang, Haiqin Song, Ying Yue, Tongjun Liu
Pages: 2347-2351
Published online on: 02 April 2014

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Article

Effects of alcohol on intestinal epithelial barrier permeability and expression of tight junction‑associated proteins

Ying Wang, Jing Tong, Bing Chang, Baifang Wang, Dai Zhang, Bingyuan Wang
Pages: 2352-2356
Published online on: 09 April 2014

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Article

Y-27632 inhibits ethanol-induced increase in intestinal epithelial barrier permeability

Jing Tong, Ying Wang, Bing Chang, Dai Zhang, Bingyuan Wang
Pages: 2357-2361
Published online on: 18 March 2014

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Article

α‑spinasterol from Melandrium firmum attenuates benign prostatic hyperplasia in a rat model

Mee‑Young Lee, In‑Sik Shin, Hwangbo Kyoung, Chang‑Seob  Seo, Jong-Keun Son, Hyeun‑Kyoo Shin
Pages: 2362-2366
Published online on: 28 March 2014

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Article

Decreased expression of Dkk1 and Dkk3 in human clear cell renal cell carcinoma

Chang‑Cheng Guo, Xiao‑Long Zhang, Bin Yang, Jiang  Geng, Bo Peng, Jun‑Hua Zheng
Pages: 2367-2373
Published online on: 27 March 2014

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Article

B‑cell translocation 1 gene inhibits cellular metastasis‑associated behavior in breast cancer

Wei Li, Shi‑Tao Zou, Ran Zhu, Jian‑Mei Wan, Yan Xu, Hao‑Rong Wu
Pages: 2374-2380
Published online on: 04 April 2014

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Article

Fuzheng Qingjie recipe induces apoptosis in HepG2 cells via P38 MAPK activation and the mitochondria-dependent apoptotic pathway

Xu-Zheng Chen, Jin-Nong Li, You-Quan Zhang, Zhi-Yun Cao, Zhi‑Zhen Liu, Su-Qing Wang, Lian-Ming Liao, Jian Du
Pages: 2381-2387
Published online on: 11 April 2014

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Article

Expression of mammalian target of rapamycin in atherosclerotic plaques is decreased under diabetic conditions: A mechanism for rapamycin resistance

Yan Zhang, Qiang Wang, Dachun Yang, De Li, Bing Tang, Yongjian Yang, Shuangtao Ma
Pages: 2388-2392
Published online on: 11 April 2014

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Article

miR‑22 inhibits proliferation and invasion in estrogen receptor α-positive endometrial endometrioid carcinomas cells Retraction in /10.3892/mmr.2021.12280

Shaoru Li, Ruili Hu, Chuanhong Wang, Fang Guo, Xiaoli Li, Shijin Wang
Pages: 2393-2399
Published online on: 08 April 2014

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Article

Downregulation of LKB1 suppresses Stat3 activity to promote the proliferation of esophageal carcinoma cells

Yu‑Qi Wang, Wei‑Min Dai, Xiang‑Yang Chu, Bo Yang, Ming Zhao, Yu'e Sun
Pages: 2400-2404
Published online on: 27 March 2014

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Article

Selective β2 adrenergic agonist increases Cx43 and miR-451 expression via cAMP-Epac

Hossein Mostafavi, Mojtaba Khaksarian, Mohammad Taghi Joghataei, Masoud Soleimani, Gholamreza Hassanzadeh, Sanaz Eftekhari, Mansooreh Soleimani, Kazem Mousavizadeh, Hajar Estiri, Sedighesadat Ahmadi, Mahmoud Reza Hadjighassem
Pages: 2405-2410
Published online on: 08 April 2014

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Article

Unc5D regulates p53‑dependent apoptosis in neuroblastoma cells

Hong Wang, Qiong Wu, Shuang Li, Bin Zhang, Zuofei Chi, Liangchun Hao
Pages: 2411-2416
Published online on: 01 April 2014

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Article

Antitumor activity of combination treatment with gefitinib and docetaxel in EGFR‑TKI‑sensitive, primary resistant and acquired resistant human non‑small cell lung cancer cells

Min Wu, Yuan Yuan, Yue‑Yin Pan, Ying Zhang
Pages: 2417-2422
Published online on: 28 March 2014

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Article

ERCC1 siRNA ameliorates drug resistance to cisplatin in gastric carcinoma cell lines

Wei Li, ZhiGang Jie, ZhengRong Li, Yi Liu, Quan Gan, YiQiu Mao, XueMin Wang
Pages: 2423-2428
Published online on: 03 April 2014

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Article

Baicalein pretreatment confers cardioprotection against acute myocardial infarction by activating the endothelial nitric oxide synthase signaling pathway and inhibiting oxidative stress

Shengyu Tan, Shenghua Zhou, Yingquan Luo
Pages: 2429-2434
Published online on: 28 March 2014

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Article

Post‑conditioning with sevoflurane induces heme oxygenase‑1 expression via the PI3K/Akt pathway in lipopolysaccharide‑induced acute lung injury

Shuangping Zhao, Jiao Wu, Lemeng Zhang, Yuhang Ai
Pages: 2435-2440
Published online on: 31 March 2014

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Article

Changes in mood states and salivary cortisol levels following two months of training in elite female water polo players

Donatella Di Corrado, Tiziano Agostini, Marco Bonifazi, Vincenzo Perciavalle
Pages: 2441-2446
Published online on: 04 April 2014

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Article

Cryptotanshinone inhibits lung tumorigenesis and induces apoptosis in cancer cells in vitro and in vivo

Liang Chen, Hui-Juan Wang, Wenli Xie, Yunyi Yao, Yan-Shan Zhang, Huiling Wang
Pages: 2447-2452
Published online on: 31 March 2014

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Article

Effect of the human SOD1‑G93A gene on the Nrf2/ARE signaling pathway in NSC‑34 cells

Fumin Wang, Yucheng Lu, Faying Qi, Quanping Su, Long  Wang, Cuiping You, Fengyuan Che, Jixu Yu
Pages: 2453-2458
Published online on: 28 March 2014

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Article

Association between common genetic variants of α2A-, α2B‑ and α2C-adrenoceptors and the risk of silent brain infarction

Jung O Kim, Young Joo Jeon, Ok Joon Kim, Seung Hun Oh, Hyun Sook Kim, Byoung Soo Shin, Doyeun Oh, Eo Jin Kim, Yun Kyung Cho, Nam Keun Kim
Pages: 2459-2466
Published online on: 27 March 2014

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Inhibition of the endogenous CSE/H2S system contributes to hypoxia and serum deprivation‑induced apoptosis in mesenchymal stem cells

Congsheng Li, Zeng Guo, Birong Guo, Yangjing Xie, Jing Yang, Ailing Wang
Pages: 2467-2472
Published online on: 03 April 2014

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Expression of integrin β1 and its significance in squamous cell carcinoma of the cervix

Ping Zhan, Ling Liu, Bin Liu, Xi‑Guang Mao
Pages: 2473-2478
Published online on: 09 April 2014

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Rapid screening for sickle cell disease by polymerase chain reaction-high resolution melting analysis

Liang Yue, Min Lin, Jiang-Tao Chen, Xiao-Fen Zhan, De-Shang Zhong, Santiago-M. Monte-Nguba, Pei-Fen Liu, Xue-Fen Pan, Jiang-Hua Huang, Xi Wang, Juan Carlos Salas Ehapo, Urbano Monsuy Eyi, Hui-Tian Yang, Li-Ye Yang
Pages: 2479-2484
Published online on: 09 April 2014

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Opposite effects of the gap junction blocker octanol on focal cerebral ischemia occluded for different durations

Wenting Ding, Lequan Zhou, Wei Liu, Li Guan, Xiaoying Li, Haimei  Liu, Fuman Yan, Jinwen Xu, Weiyong Zeng, Min Qiu
Pages: 2485-2490
Published online on: 27 March 2014

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microRNA-133b downregulation and inhibition of cell proliferation, migration and invasion by targeting matrix metallopeptidase‑9 in renal cell carcinoma

Deyao Wu, Huixing Pan, Yunfeng Zhou, Jian Zhou, Yuanfeng Fan, Ping Qu
Pages: 2491-2498
Published online on: 04 April 2014

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Silencing of cyclooxygenase‑2 inhibits the growth, invasion and migration of ovarian cancer cells

Yang Lin, Manhua Cui, Tianmin Xu, Wei Yu, Lihui Zhang
Pages: 2499-2504
Published online on: 09 April 2014

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Inhibition of HepG2 cell proliferation by ursolic acid and polysaccharides via the downregulation of cyclooxygenase-2

Ling Liu, Jingkai Zhang, Meiling Li, Xiaohong Zhang, Jinlu Zhang, Zhenjing Li, Likui Wang, Jihui Wu, Cheng Luo
Pages: 2505-2511
Published online on: 17 March 2014

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ABCG5/8 variants are associated with susceptibility to coronary heart disease

Ge Wu, Gui-Bin Li, Ming Yao, Dong-Qing Zhang, Bin Dai, Chuan-Jing Ju, Ming Han
Pages: 2512-2520
Published online on: 01 April 2014

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Effects of partial deletion of the wzm and wzt genes on lipopolysaccharide synthesis and virulence of Brucella abortus S19

Xiuran Wang, Lin Wang, Tiancheng Lu, Yanling Yang, Si  Chen, Rui Zhang, Xulong  Lang, Guangmou  Yan, Jing  Qian, Xiaoxu Wang, Lingyi Meng, Xinglong Wang
Pages: 2521-2527
Published online on: 02 April 2014

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Resveratrol attenuates the inflammatory reaction induced by ischemia/reperfusion in the rat heart

Xiaoqiang Cong, Ying Li, Na Lu, Yajian Dai, Huijie Zhang, Xin Zhao, Ya Liu
Pages: 2528-2532
Published online on: 28 March 2014

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Ursolic acid suppresses growth and adrenocorticotrophic hormone secretion in AtT20 cells as a potential agent targeting adrenocorticotrophic hormone‑producing pituitary adenoma

Ying‑Ying Gong, Yuan‑Yuan Liu, Shuang Yu, Xiao‑Nan Zhu, Xiao‑Pei Cao, Hai‑Peng Xiao
Pages: 2533-2539
Published online on: 27 March 2014

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Article

GPC5, a tumor suppressor, is regulated by miR‑620 in lung adenocarcinoma

Zhengyuan Zhao, Chengguang Han, Juntao Liu, Changlei Wang, Yi Wang, Liya Cheng
Pages: 2540-2546
Published online on: 28 March 2014

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Involvement of β‑catenin in matrine‑induced autophagy and apoptosis in WB‑F344 cells

Bu‑Shan Xie, Xing‑Xing He, Zheng‑Lin Ai, Shu‑Kun Yao
Pages: 2547-2553
Published online on: 02 April 2014

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Chronic leucine exposure results in reduced but reversible glucose-stimulated insulin secretion in INS-1 cells

Xiujuan Zhang, Wenxia Han, Xiuyun Jiang, Min Li, Ling Gao, Jia Jun Zhao
Pages: 2554-2558
Published online on: 08 April 2014

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Article

Enhancement of transfection efficiency with NLS and SPB‑NLS

Jian Lin, Tao Qin, Li Qi Zhu, Qiang Zhang, Qing Hua Yu, Qian Yang
Pages: 2559-2567
Published online on: 08 April 2014

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Article

Structure‑activity relationship of 1‑desamino‑8‑D‑arginine vasopressin as an antiproliferative agent on human vasopressin V2 receptor‑expressing cancer cells

María B. Pastrian, Fanny Guzmán, Juan Garona, Marina Pifano, Giselle V. Ripoll, Osvaldo Cascone, Graciela N. Ciccia, Fernando Albericio, Daniel E. Gómez, Daniel F. Alonso, Nancy B. Iannucci
Pages: 2568-2572
Published online on: 11 April 2014

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Neuroprotective effect of Atractylodes macrocephalaon polysaccharides in vitro on neuronal apoptosis induced by hypoxia

Wei‑Xu Hu, Qin Xiang, Zhu Wen, Dan He, Xiao‑Mu Wu, Guo‑Zhu Hu
Pages: 2573-2581
Published online on: 02 April 2014

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CDK3 expression and its clinical significance in human nasopharyngeal carcinoma

Liang Wang, Hong‑Yi Hu, Yi‑Ling Lin, Zhi‑Xiang Zhao, Lu Tan, Peng Yu, Hui‑Juan Wan, Zhe Jin, Duo Zheng
Pages: 2582-2586
Published online on: 31 March 2014

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Article

MG132 reverse the malignant characteristics of hypopharyngeal cancer

Juke Ma, Liang Yu, Jiajun Tian, Yakui Mu, Zhenghua Lv, Jidong Zou, Jianfeng Li, Haibo Wang, Wei Xu
Pages: 2587-2591
Published online on: 01 April 2014

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Anti‑inflammatory effect of resveratrol on adjuvant arthritis rats with abnormal immunological function via the reduction of cyclooxygenase‑2 and prostaglandin E2

Xiaoyu Chen, Jinseng Lu, Mei An, Zhongfei Ma, Hexiang Zong, Jun Yang
Pages: 2592-2598
Published online on: 24 March 2014

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Melatonin reduces inflammation and recovers endogenous ghrelin in acute necrotizing pancreatitis in rats

Zhi‑Hai Liang, Meng‑Bin Qin, Guo‑Du Tang, Hui‑Ying Yang, Juan Su, Jie‑An Huang
Pages: 2599-2605
Published online on: 09 April 2014

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Journal Cover
June-2026 Volume 33 Issue 6

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Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

Mechanotransducer Piezo1 drives ventilator‑induced lung injury in lung epithelial cells via the calcineurin/NFATc3 pathway

Min Li, Shu-Li Zhang, Feng Yuan, Dan Feng
Article Number: 183
Published online on: 28 April 2026

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Oncogene c‑Myc: From molecular mechanism to targeted therapy (Review)

Jianjun Lu, Jing Zhu, Liqiong Zhang, Xiang Zheng, Shan Yang, Yatong Sang, Mingli Yang, Yu Tang
Article Number: 182
Published online on: 28 April 2026

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Indium (III) chloride inhibits testicular Leydig cell proliferation by disrupting centrosome copy numbers

Chia-Yih Wang, Ping-Jui Su, Kuan-Chih Wang, Ruei-Ci Lin, Min-Yun Ke, Yen-Ni Teng
Article Number: 181
Published online on: 28 April 2026

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Correction Open Access

[Corrigendum] Inhibition of DNA‑PK activity sensitizes A549 cells to X‑ray irradiation by inducing the ATM‑dependent DNA damage response

Lina Yang, Xinrui Yang, Yiwei Tang, Defu Zhang, Lijie Zhu, Shengnan Wang, Bo Wang, Tao Ma
Article Number: 180
Published online on: 27 April 2026

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Natural products and neurocognitive disorders: Mechanistic insights and research advances (Review)

Weiqing Li, Wei Wu, Xiaoqing Huang, Yinghai Liu, Gu Gong, Qingqing Huang
Article Number: 179
Published online on: 27 April 2026

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Research progress and future directions in circadian rhythms for uterine‑related diseases (Review)

Tiantian Ma, Junwei Li, Yi Fang, Tiancheng Xu, Qian Li, Liangjun Xia, Youbing Xia
Article Number: 178
Published online on: 27 April 2026

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Therapeutic potential of tertiary lymphoid structures in breast cancer (Review)

Liangxiao Zhu, Meigui Li, Feng Liu, Fenghou Gao
Article Number: 177
Published online on: 24 April 2026

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Retraction Open Access

[Retracted] Prognostic and predictive roles of microRNA‑411 and its target STK17A in evaluating radiotherapy efficacy and their effects on cell migration and invasion via the p53 signaling pathway in cervical cancer

Wei Wei, Cun Liu
Article Number: 176
Published online on: 22 April 2026

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Insights into nuciferine: A natural multifunctional bioactive alkaloid (Review)

Yulin Liu, Xinye Li, Bo Huang, Xudong Lai, Baoqing Ye, Haixiong Miao, Lixian Zhang, Xifeng Xiong
Article Number: 175
Published online on: 22 April 2026

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Article

Urinary 8‑OHdG and MDA as rapid biodosimetry markers in the lethal/sublethal dose range

Satoru Monzen, Kenji Terada, Yusuke Tawata, Takanori Sato, Nozomi Kousaka, Yasushi Mariya
Article Number: 174
Published online on: 22 April 2026

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[Retracted] Treatment with harmine ameliorates functional impairment and neuronal death following traumatic brain injury  

Zeqi Zhong, Yuan Tao, Hui Yang
Article Number: 173
Published online on: 20 April 2026

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SRSF1 as a promising biomarker and key player in the pathogenesis of Alzheimer's disease

Yanchen Liu, Yi Zhao, Yanting Yao, Dan Liu, Yilei Sun, Weishi Xu, Hongli Yu, Lijun Chi
Article Number: 172
Published online on: 17 April 2026

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RUVBL1 and CRAF promote periodontal ligament stem cell osteogenic differentiation via the MEK/ERK signaling cascade

Xin-Yu Zhang, Peiqi Hao, Ming-Yue Qi, Hui Guo
Article Number: 171
Published online on: 16 April 2026

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Porphyromonas gingivalis triggers lipid metabolism disorders in atherosclerosis through the PPARγ-LXRα‑ABCA1/ABCG1 signaling pathway

Xue-Jing Lin, Min Yao, Wan-Yun Lin, Qin Yuan, Jie Zhou, Wen-Xuan Xia, Yu-Lei Dong, Miao-Miao Zhang, Ming-Wang Cui, Lin-Han Wu, Diwas Sunchuri, Muhammad Zia Ullah Shahid, Zhu-Ling Guo
Article Number: 170
Published online on: 16 April 2026

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[Corrigendum] MicroRNA‑122 acts as tumor suppressor by targeting TRIM29 and blocking the activity of PI3K/AKT signaling in nasopharyngeal carcinoma in vitro

Yan Yang, Qing Li, Lili Guo
Article Number: 169
Published online on: 15 April 2026

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Elevated IgG levels induce an M2‑to‑M1 phenotypic shift in mucosal macrophages and restrict the growth of invasive sphenoid sinus pituitary adenomas

Xingbo Li, Zhuowei Lei, Sihan Li, Linpeng Xu, Quanji Wang, Qian Jiang, Zihan Wang, Huaqiu Zhang, Yimin Huang, Ting Lei
Article Number: 168
Published online on: 14 April 2026

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[Retracted] SUMO1/UBC9‑decreased Nox1 activity inhibits reactive oxygen species generation and apoptosis in diabetic retinopathy

Jiaoli Hu, Pengcheng Xue, Xinbang Mao, Lin Xie, Guodong Li, Zhipeng You
Article Number: 167
Published online on: 14 April 2026

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Potential for anti‑angiogenic therapy targeting the receptor for advanced glycation end products/VEGF axis in ulcerative colitis (Review)

Chen Xu, Yuting Li, Yahua Hong, Dayong Zhou, Kun He, Lianghui Wang, Feng Hong
Article Number: 166
Published online on: 09 April 2026

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[Retracted] Molecular mechanisms underlying mangiferin‑induced apoptosis and cell cycle arrest in A549 human lung carcinoma cells

Wei Shi, Jiagang Deng, Rongsheng Tong, Yong Yang, Xia He, Jianzhen Lv, Hailian Wang, Shaoping Deng, Ping Qi, Dingding Zhang, Yi Wang
Article Number: 165
Published online on: 07 April 2026

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Mechanism of and research progress on alterations in the RET gene in thyroid cancer (Review)

Meng Wei, Rui Wang, Jincan Qian, Qiang Fang, Jun Tao
Article Number: 164
Published online on: 02 April 2026

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Current research progress on extracellular vesicles derived from mesenchymal stem cells in tuberculosis treatment (Review)

Dejun Fan, Yan Yang, Li Yang
Article Number: 163
Published online on: 01 April 2026

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Uremic toxin p‑cresyl sulfate enhances the calcification of aortic valvular interstitial cells via klotho/sirtuin‑1 signaling

Shao-Jung Li, Tzu-Yu Cheng, Yu-Hsun Kao, Wei-Yu Chen, Cheng-Chih Chung, Nguyen Ngoc Trang, Pao-Huan Chen, Yi-Jen Chen
Article Number: 162
Published online on: 01 April 2026

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Exercise‑induced extracellular vesicle microRNA regulates physiological function (Review)

Zhonglei Wang, Wenjue Guo, Haojia He, Yi Zhang, Na Li
Article Number: 161
Published online on: 01 April 2026

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Expression of Concern Open Access

[Expression of Concern] Electroacupuncture at GV20‑GB7 regulates mitophagy to protect against neurological deficits following intracerebral hemorrhage via inhibition of apoptosis

Ruiqiao Guan, Zhihao Li, Xiaohong Dai, Wei Zou, Xueping Yu, Hao Liu, Qiuxin Chen, Wei Teng, Peng Liu, Xiaoying Liu, Shanshan Dong
Article Number: 160
Published online on: 01 April 2026

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Emerging roles of POLR2L of RNA polymerase II dynamics and disease mechanisms (Review)

Beomwoo Lee, Changgyu Son, Sunho Eom, Yuwen Li, Seon-Hwan Kim, Jongsun Park
Article Number: 159
Published online on: 30 March 2026

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Combining bioinformatics prediction with experimental validation to explore the ameliorative effect of Psoralea corylifolia on vitiligo

Chen Zhang, Zhanhong Cao, Mengyang Wei, Xuanxuan Zhu, Yan Yan, Zhenhua Wang, Meng Zhang
Article Number: 158
Published online on: 30 March 2026

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[Retracted] All‑trans‑retinoic acid inhibits chondrogenesis of rat embryo hindlimb bud mesenchymal cells by down­regulating p53 expression

Tao-Gen Zhang, Xue-Dong Li, Guo-Yong Yu, Peng Xie, Yun-Guo Wang, Zhao-Yong Liu, Quan Hong, De-Zhong Liu, Shi-Xin Du
Article Number: 157
Published online on: 30 March 2026

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Journal Cover
July-2026 Volume 34 Issue 1

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Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Targeting lipophagy in atherosclerosis: Molecular mechanisms, pathogenesis and therapeutic interventions (Review)

Songhua Nan, Chaojie Peng, Xue Meng, Jingnan Jia, Fangfang Zhao, Yinglin Cui
Article Number: 208
Published online on: 22 May 2026

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Mechanisms of pruritus and advances in traditional Chinese medicine therapy (Review)

Hailing Zhang, Yongji Li, Yuan Liu, Danyi Feng, Letao Zhao, Ran Chen, Xiwu Zhang, Jinjin Dou
Article Number: 207
Published online on: 22 May 2026

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Reprogramming of the hepatic ubiquitin‑immune axis: A unifying mechanism in liver disease progression (Review)

Yadi Ju, Xiaodan Chong, Weichen Ning, Yan Shi, Yangyang Li, Yihai Shi
Article Number: 206
Published online on: 22 May 2026

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Role of the PI3K/AKT signaling pathway in regulating gene expression in rheumatoid arthritis (Review)

Chengzhi Cong, Yuan Wang, Jian Liu, Chao Jin
Article Number: 205
Published online on: 21 May 2026

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Biomarkers of radioresistance in lung cancer: Current insights and future directions (Review)

Fatima Zohra Attouahri, Imane Chaoui, Abdelilah Laraqui, Mohamed Rida Tagajdid, Mohammed Oukabli, Mohammed El Marjany, Meriem Khyatti, Mohammed Attaleb, Mouna Ababou, Khalid Ennibi, Khaoula Errafii, Mohammed El Mzibri
Article Number: 204
Published online on: 21 May 2026

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Epigenetic research methods and animal models for intervertebral disc degeneration (Review)

Xinliang Cui, Li Zeng, Wei Zhang, Leimin Xi, Rui Wang, Diff Jia, Safa, Haoyu Feng, Huidong Jia
Article Number: 203
Published online on: 21 May 2026

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ZBTB16 upregulation maintains copper homeostasis to support esophageal tumor progression

Jingyi Wang, Bin Yang, Shengzu Peng
Article Number: 202
Published online on: 21 May 2026

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[Corrigendum] MicroRNA‑1 promotes cartilage matrix synthesis and regulates chondrocyte differentiation via post‑​transcriptional suppression of Ihh expression  

Taoyu Chen, Xianda Che, Pengfei Han, Jiangong Lu, Chunfang Wang, Bin Liang, Ziqi Hou, Xiaochun Wei, Lei Wei, Pengcui Li
Article Number: 201
Published online on: 20 May 2026

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Estrogen deficiency as a common driver and integrative mechanism in osteoporosis‑osteoarthritis comorbidity (Review)

Jian Cheng, Xiaodong Wu, Lu Zhao, Shuai Jiang, Wenjie Zhao, Weishuai Zhang
Article Number: 200
Published online on: 20 May 2026

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Role of RNA 5‑methylcytosine modification in cancer: Insights from coding and non‑coding RNAs (Review)

Qin Jiang, Yi Gong, Mimi Zhai, Tenglong Tang, Sushun Liu
Article Number: 199
Published online on: 20 May 2026

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m6A modification in skeletal system diseases (Review)

Xi Xie, Chen Li, Haotian Zheng, Guang Gan, Xi Gao
Article Number: 198
Published online on: 19 May 2026

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Dynamic regulation of the ‘mitochondria‑immune axis’ in myocardial infarction: Molecular mechanisms driving macrophage polarization through energy metabolism disorders (Review)

Yu Zhang, Hao Feng, Qin Wu, Shuxian Yang, Yundong Jiang, Houping Xu, Li Dong, Xiaolin Li, Hui Chen, Gang Luo
Article Number: 197
Published online on: 19 May 2026

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[Retracted] Homeobox B9 facilitates hypertrophic scar formation via activating the mitogen‑activated protein kinase signaling pathway

Qun Xie, Dandan Liu, Mosheng Yu, Xiaowei Wu, Yueqiang Zhao, Qiang Hu, Qi Wang
Article Number: 196
Published online on: 18 May 2026

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Polysaccharides: Natural candidates for targeting immunometabolic regulation in hepatocellular carcinoma (Review)

Changmei Wu, Jinjin Dou, Xiwu Zhang
Article Number: 195
Published online on: 18 May 2026

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NF‑κB signaling drives Th17‑mediated lacrimal gland injury and tear dysfunction in a murine model of primary Sjögren's syndrome

Jiajun Xie, Huina Zhang, Wenyue Shen, Juan Ye
Article Number: 194
Published online on: 18 May 2026

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POSTN(+) fibroblasts and SPP1(+) macrophages in scar formation: A review of mechanisms and therapeutic targets (Review)

Haotian Wu, Xianglin Dong
Article Number: 193
Published online on: 15 May 2026

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Emerging role of DYRK1A as a target in cardiovascular diseases (Review)

Liqing Yu, Qionghong Cheng, Jun Wu
Article Number: 192
Published online on: 15 May 2026

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[Retracted] Resveratrol pretreatment attenuates traumatic brain injury in rats by suppressing NLRP3 inflammasome activation via SIRT1

Peng Zou, Xiaoxiao Liu, Gang Li, Yangang Wang
Article Number: 191
Published online on: 05 May 2026

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Gut microbiota and its metabolites: Key factors of drug resistance in the treatment of advanced prostate cancer (Review)

Jingheng Song, Hongguo Cui, Peisen Yang, Yankai Xu, Yuanyuan Liu, Gang Zhang, Yangyang Liu, Aimin Tian, Jizhong Che, Hui Sun, Zhengchao Zhang
Article Number: 190
Published online on: 04 May 2026

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Article Open Access

Cepharanthine inhibits lysosomes and induces apoptosis in triple‑negative breast cancer cells

Juan Li, Siqin Zhou, Yu Wang, Guanghan Ou, Danli Yang, Liwen Shen
Article Number: 189
Published online on: 04 May 2026

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Applications of humanized mice in Mycobacterium tuberculosis infections (Review)

Binghua Han, Fang Liu, Jinzhao Long, Jiongjiong Wang, Yange Cui, Haiyan Yang
Article Number: 188
Published online on: 04 May 2026

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Research progress on neutrophil extracellular traps in sepsis‑induced coagulopathy (Review)

Jiandong Hu, Mengli Jin, Zhihua Cao, Binbin Zheng, Yuan Zheng, Hao Shen
Article Number: 187
Published online on: 04 May 2026

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Multifaceted regulatory role of proline‑ and glutamine-rich splicing factor in tumors (Review)

Shilin Zhang, Zhenhua Li, Li Fu
Article Number: 186
Published online on: 04 May 2026

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Effects of ALDH2 gene expression on the oxidative stress‑mediated NF‑κB/mTOR pathway in ketamine‑induced cystitis

Xiao Jian Xi, Yong Yao, Peng Gu, Min Hao Zhang
Article Number: 185
Published online on: 04 May 2026

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Retraction Open Access

[Retracted] Rosiglitazone exerts neuroprotective effects via the suppression of neuronal autophagy and apoptosis in the cortex following traumatic brain injury

Junchao Yao, Kebin Zheng, Xiang Zhang
Article Number: 184
Published online on: 29 April 2026

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