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Molecular Medicine Reports
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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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July-2019 Volume 20 Issue 1

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Advances in nanomaterials for use in photothermal and photodynamic therapeutics (Review)

Zhizhou Yang, Zhaorui Sun, Yi Ren, Xin Chen, Wei Zhang, Xuhui Zhu, Zongwan Mao, Jianliang Shen, Shinan Nie
Pages: 5-15
Published online on: 09 May 2019

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Article

Association between quasispecies variants of hepatitis B virus, as detected by high‑throughput sequencing, and progression of advanced liver disease in Indonesian patients

Wahyu Aristyaning Putri, Yoshihiko Yano, Laura Navika Yamani, Yujiao Liang, Yan Mardian, Takako Utsumi, Soetjipto Soetjipto, Maria Inge Lusida, Yoshitake Hayashi
Pages: 16-24
Published online on: 16 May 2019

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Article

Administration of live, but not inactivated, Faecalibacterium prausnitzii has a preventive effect on dextran sodium sulfate‑induced colitis in mice

Yujiro Kawade, Misaki Sakai, Mariko Okamori, Mayuko Morita, Katsura Mizushima, Tomohiro Ueda, Tomohisa Takagi, Yuji Naito, Yoshito Itoh, Takashi Shimada
Pages: 25-32
Published online on: 14 May 2019

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Article Open Access

miR‑338‑3p inhibits A549 lung cancer cell proliferation and invasion by targeting AKT and β‑catenin signaling pathways

Jia Liu, Linggai Cao, Na Zhao, Yue Feng, Ze Yu, Yuhua Li, Chunbo Teng, Jifan Hu, Tao Li
Pages: 33-40
Published online on: 09 May 2019

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Article Open Access

Neuregulin‑1 impacting bone marrow mesenchymal stem cell migration is conducive to functional recovery following spinal cord injury

Xi‑Meng Yi, Yi Chen, Guan‑Jun Tu
Pages: 41-48
Published online on: 09 May 2019

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Article

The protective effect of the TUG1/miR‑197/MAPK1 axis on lipopolysaccharide‑induced podocyte injury

Dong Zhao, Zheng Liu, Heng Zhang
Pages: 49-56
Published online on: 09 May 2019

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Article Open Access

MicroRNA‑34a inhibits cell growth and migration in human glioma cells via MMP‑9

Xuepeng Wang, Xi Chen, Lin Sun, Xiaoli Bi, Haitao He, Lei Chen, Jinfeng Pang
Pages: 57-64
Published online on: 13 May 2019

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Article

A novel mutation associated with Type III Bartter syndrome: A report of five cases

Yanhan Li, Chengcheng Wu, Jie Gu, Dong Li, Yanling Yang
Pages: 65-72
Published online on: 16 May 2019

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Article

Bryonia dioica aqueous extract induces apoptosis and G2/M cell cycle arrest in MDA‑MB 231 breast cancer cells

Bachir Benarba, Almahy Elmallah, Atanasio Pandiella
Pages: 73-80
Published online on: 09 May 2019

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Article Open Access

miRNA‑30a‑3p inhibits metastasis and enhances radiosensitivity in esophageal carcinoma by targeting insulin‑like growth factor 1 receptor Retraction in /10.3892/mmr.2026.13822

Yanxin Fan, Xiuhua Bian, Pudong Qian, Jing Wen, Pengwei Yan, Yanhong Luo, Jing Wu, Qian Zhang
Pages: 81-94
Published online on: 09 May 2019

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Article Open Access

Possibility of early diagnosis in a fetus affected by Prader‑Willi syndrome with maternal hetero‑UPD15: A lesson to be learned

Yanling Dong, Shu Liu, Junnan Li, Jian Li, Qian Chen, Jianyun Luo, Chunlei Li, Huifan Li, Hongbo Qi, Rong Li
Pages: 95-102
Published online on: 15 May 2019

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Article

Contribution of sex‑based immunological differences to the enhanced immune response in female mice following vaccination with hepatitis B vaccine

Meng Li, Yuwei Zhao, Xue Chen, Xuemei Fu, Wen Li, Humin Liu, Yufang Dong, Chuanyao Liu, Xiao Zhang, Li Shen, Bing Li, Yaomei Tian
Pages: 103-110
Published online on: 10 May 2019

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Article Open Access

Role of FN1 and GREB1 gene polymorphisms in endometriosis

Charoula Matalliotaki, Michail Matalliotakis, Nilufer Rahmioglu, George Mavromatidis, Ioannis Matalliotakis, George Koumantakis, Krina Zondervan, Demetrios A. Spandidos, George N. Goulielmos, Maria I. Zervou
Pages: 111-116
Published online on: 15 May 2019

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Article

Adenosine A2a receptor agonist CGS21680 treatment attenuates cardiopulmonary bypass‑associated inflammatory lung injury in juvenile rats

Xiang Kong, Yi Zuo, Yu'ang Huang, Jianjun Ge
Pages: 117-124
Published online on: 14 May 2019

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Article Open Access

ILF3 promotes gastric cancer proliferation and may be used as a prognostic marker

Yü Liu, Yong Li, Yijie Zhao, Yang Liu, Liqiao Fan, Nan Jia, Qun Zhao
Pages: 125-134
Published online on: 09 May 2019

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Article Open Access

Toosendanin induces the apoptosis of human Ewing's sarcoma cells via the mitochondrial apoptotic pathway

Tian Gao, An Xie, Xuqiang Liu, Haibo Zhan, Jin Zeng, Min Dai, Bin Zhang
Pages: 135-140
Published online on: 09 May 2019

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Article Open Access

Cathepsin S regulates renal fibrosis in mouse models of mild and severe hydronephrosis

Xiaobing Yao, Fan Cheng, Weiming Yu, Ting Rao, Wei Li, Sheng Zhao, Xiangjun Zhou, Jinzhuo Ning
Pages: 141-150
Published online on: 09 May 2019

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Article Open Access

ΜicroRNA‑421 promotes the progression of non‑small cell lung cancer by targeting HOPX and regulating the Wnt/β‑catenin signaling pathway

Huagang Liang, Chao Wang, Kun Gao, Jian Li, Rui Jia
Pages: 151-161
Published online on: 09 May 2019

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Article Open Access

FGF signaling contributes to atherosclerosis by enhancing the inflammatory response in vascular smooth muscle cells

Ming Qi, Shijie Xin
Pages: 162-170
Published online on: 16 May 2019

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Article Open Access

miR‑10b‑3p, miR‑8112 and let‑7j as potential biomarkers for autoimmune inner ear diseases

Juhong Zhang, Na Wang, Anting Xu
Pages: 171-181
Published online on: 16 May 2019

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Article Open Access

Long non‑coding RNA FER1L4 inhibits cell proliferation and metastasis through regulation of the PI3K/AKT signaling pathway in lung cancer cells

Xuejin Gao, Nianchang Wang, Shanshan Wu, Hongmei Cui, Xue An, Yuping Yang
Pages: 182-190
Published online on: 09 May 2019

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Article

Regulatory effects of Ningdong granule on dopaminergic and serotonergic neurotransmission in a rat model of Tourette syndrome assessed by PET

Yuan Wang, Anyuan Li
Pages: 191-197
Published online on: 15 May 2019

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Article Open Access

Striatisporolide A, a butenolide metabolite from Athyrium multidentatum (Doll.) Ching, as a potential antibacterial agent

Ji‑Wen Sheng, Dong‑Mei Liu, Liang Jing, Gui‑Xue Xia, Wei‑Fen Zhang, Jing‑Ru Jiang, Jin‑Bao Tang
Pages: 198-204
Published online on: 15 May 2019

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Article Open Access

Thermal pretreatment promotes the protective effect of HSP70 against tendon adhesion in tendon healing by increasing HSP70 expression

Xiao‑Ming Tang, Jian Dai, Hai‑Lang Sun
Pages: 205-215
Published online on: 15 May 2019

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Article

Identification of pathogenic genes and transcription factors in glaucoma

Jie Feng, Jing Xu
Pages: 216-224
Published online on: 14 May 2019

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Article Open Access

Integrated bioinformatic analysis of differentially expressed genes and signaling pathways in plaque psoriasis

Yu‑Jing Zhang, Yu‑Zhe Sun, Xing‑Hua Gao, Rui‑Qun Qi
Pages: 225-235
Published online on: 15 May 2019

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Article Open Access

MicroRNA‑30a‑5p promotes proliferation and inhibits apoptosis of human pulmonary artery endothelial cells under hypoxia by targeting YKL‑40

Hong Tan, Hua Yao, Zhenbang Lie, Guo Chen, Shuguang Lin, Ying Zhang
Pages: 236-244
Published online on: 16 May 2019

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Article Open Access

Transcriptomics analysis of sirolimus treatment in lupus nephritis

Dongdong Wang, Xiao Chen, Meng Fu, Zhiping Li
Pages: 245-251
Published online on: 14 May 2019

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Article Open Access

miR‑342 inhibits glioma cell proliferation by targeting GPRC5A

Jianjiao Wang, Yan Yang, Yuandong Cao, Xinyu Tang
Pages: 252-260
Published online on: 15 May 2019

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Article

ΜicroRNA‑889 plays a suppressive role in cell proliferation and invasion by directly targeting TAB1 in non‑small cell lung cancer

Zheng Dong, Bingchun Li, Xiaojuan Wang
Pages: 261-269
Published online on: 15 May 2019

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Article Open Access

miR‑144 promotes the proliferation and differentiation of bone mesenchymal stem cells by downregulating the expression of SFRP1

Ling Tang, Wenjun Lu, Jian Huang, Xu Tang, Huiyun Zhang, Shujiao Liu
Pages: 270-280
Published online on: 16 May 2019

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Article Open Access

Bioinformatics identification of microRNAs involved in polycystic ovary syndrome based on microarray data

Yan Hou, Yaoqin Wang, Suming Xu, Gaimei Qi, Xueqing Wu
Pages: 281-291
Published online on: 16 May 2019

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Article Open Access

Downregulation of the long non‑coding RNA FOXD2‑AS1 inhibits cell proliferation, migration and invasion in osteosarcoma

Haomeng Zhang, Yao Lu, Jun Wang, Tian Zhang, Chuan Dong, Xiaoxiang Li, Xinli Wang, Qiong Ma, Tongtao Yang, Yong Zhou
Pages: 292-302
Published online on: 16 May 2019

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Article

Bioinformatics‑based identification of key pathways and candidate genes for estrogen‑induced intrahepatic cholestasis using DNA microarray analysis

Dong Xiang, Yanjiao Xu, Wenxi He, Jinyu Yang, Chengliang Zhang, Dong Liu
Pages: 303-311
Published online on: 16 May 2019

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Article Open Access

Costunolide inhibits matrix metalloproteinases expression and osteoarthritis via the NF‑κB and Wnt/β‑catenin signaling pathways

Yuzhe He, Safwat Adel Abdo Moqbel, Langhai Xu, Jisheng Ran, Chiyuan Ma, Kai Xu, Jiapeng Bao, Lifeng Jiang, Weiping Chen, Yan Xiong, Lidong Wu
Pages: 312-322
Published online on: 14 May 2019

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Article Open Access

TFAP2E methylation promotes 5‑fluorouracil resistance via exosomal miR‑106a‑5p and miR‑421 in gastric cancer MGC‑803 cells

Sun Jingyue, Wang Xiao, Zha Juanmin, Li Wei, Li Daoming, Xu Hong
Pages: 323-331
Published online on: 14 May 2019

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Article

Saikosaponin‑D improves fear memory deficits in ovariectomized rats via the action of estrogen receptor‑α in the hippocampus

Lina Liu, Jing Yan, Fei Ge, Xiangtao Xu, Jun Lu, Huilian Shi, Shuihong Li, Yue Zhao, Changzheng Zhang
Pages: 332-340
Published online on: 10 May 2019

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Article Open Access

Formaldehyde induces the apoptosis of BMCs of BALB/c mice via the PTEN/PI3K/Akt signal transduction pathway

Guangyan Yu, Chunhua Wang, Xiangfu Song, Shimeng Liu, Yixin Zhang, Lida Fan, Yixue Yang, Yulu Huang, Jiayi Song
Pages: 341-349
Published online on: 09 May 2019

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Article Open Access

Mechanism of interactions between endoplasmic reticulum stress and autophagy in hypoxia/reoxygenation‑induced injury of H9c2 cardiomyocytes

Gaopeng Guan, Lei Yang, Wenyin Huang, Jun Zhang, Puhua Zhang, Huan Yu, Shengyuan Liu, Xiang Gu
Pages: 350-358
Published online on: 09 May 2019

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Article Open Access

Fr‑HMGB1 and ds‑HMGB1 activate the kynurenine pathway via different mechanisms in association with depressive‑like behavior

Bo Wang, Yong‑Jie Lian, Wen‑Jun Su, Lin‑Lin Liu, Jia‑Mei Li, Chun‑Lei Jiang, Yun‑Xia Wang
Pages: 359-367
Published online on: 09 May 2019

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Article

Downregulation of syndecan‑1 expression induces activation of hepatic stellate cells via the TGF‑β1/Smad3 signaling pathway

Min Deng, Longsheng Xu, Xinsheng Xie, Xiong Sheng, Zhuolin Zou, Ming Yao
Pages: 368-374
Published online on: 09 May 2019

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Article Open Access

Identification and integrative analysis of microRNAs and mRNAs involved in proliferation and invasion of pressure‑treated human liver cancer cell lines

Si Shen, Xu Luo, Kewei Gao, Yunchen Sun, Dingkang Yao, Liang Zhu
Pages: 375-387
Published online on: 09 May 2019

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Article Open Access

Identification of claudin‑1, ‑3, ‑7 and ‑8 as prognostic markers in human laryngeal carcinoma

Shu Zhou, Xue Piao, Chengyan Wang, Rui Wang, Zhimin Song
Pages: 393-400
Published online on: 22 May 2019

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Article Open Access

Crocin protects against dexamethasone‑induced osteoblast apoptosis by inhibiting the ROS/Ca2+‑mediated mitochondrial pathway Retraction in /10.3892/mmr.2025.13561

Zhigang Nie, Shuang Deng, Lei Zhang, Sen Chen, Qiang Lu, Hao Peng
Pages: 401-408
Published online on: 22 May 2019

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Article Open Access

Amyloid β precursor protein silencing attenuates epithelial‑mesenchymal transition of nasopharyngeal carcinoma cells via inhibition of the MAPK pathway

Jin Xu, Yin Ying, Gaoyun Xiong, Liqin Lai, Qingliang Wang, Yue Yang
Pages: 409-416
Published online on: 24 May 2019

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Article Open Access

Bioinformatics analysis of a long non‑coding RNA and mRNA regulation network in rats with middle cerebral artery occlusion based on RNA sequencing

Xianchun Duan, Lan Han, Daiyin Peng, Can Peng, Ling Xiao, Qiuyu Bao, Huasheng Peng
Pages: 417-432
Published online on: 27 May 2019

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Article Open Access

De novo transcriptome analysis of gene responses to pest feeding in leaves of Panax ginseng C. A. Meyer

Guangsheng Xi, Yanling Wang, Le Yin, Yunjia Wang, Shengxue Zhou
Pages: 433-444
Published online on: 22 May 2019

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Article Open Access

High developmental pluripotency‑associated 4 expression promotes cell proliferation and glycolysis, and predicts poor prognosis in non‑small‑cell lung cancer

Longfei Li, Yufeng Wang, Qiang Wang, Jingming Qu, Xiangju Wei, Jilei Xu, Yuanjin Wang, Feng Suo, Yangjie Zhang
Pages: 445-454
Published online on: 22 May 2019

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Article Open Access

Synergistic protection of matrine and lycopene against lipopolysaccharide‑induced acute lung injury in mice

Wu‑Wei Li, Tao‑Yuan Wang, Bo Cao, Bin Liu, Yu‑Mei Rong, Juan‑Juan Wang, Fei Wei, Lu‑Qing Wei, Hong Chen, Yan‑Xia Liu
Pages: 455-462
Published online on: 22 May 2019

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Article Open Access

Resveratrol alleviates inflammatory injury and enhances the apoptosis of fibroblast‑like synoviocytes via mitochondrial dysfunction and ER stress in rats with adjuvant arthritis

Jinsen Lu, Yongshun Zheng, Jiazhao Yang, Junqiang Zhang, Wei Cao, Xiaoyu Chen, Shiyuan Fang
Pages: 463-472
Published online on: 22 May 2019

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Article Open Access

Paneth cell ablation increases the small intestinal injury during acute necrotizing pancreatitis in rats

Liyan Liu, Yuecheng Guo, Junyuan Zheng, Yingying Lu, Yucui Shen, Chunlan Huang, Yue Zeng, Xingpeng Wang
Pages: 473-484
Published online on: 22 May 2019

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Article Open Access

Identification of a lncRNA‑associated competing endogenous RNA‑regulated network in clear cell renal cell carcinoma

Beibei Liu, Tantu Ma, Qingwen Li, Sheng Wang, Wei Sun, Wenyong Li, Jianmin Liu, Yuanyuan Guo
Pages: 485-494
Published online on: 23 May 2019

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Article Open Access

Carnosic acid alleviates brain injury through NF‑κB‑regulated inflammation and Caspase‑3‑associated apoptosis in high fat‑induced mouse models

Yong Liu, Yan Zhang, Ming Hu, Yu‑Hu Li, Xing‑Hua Cao
Pages: 495-504
Published online on: 27 May 2019

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Article Open Access

Novel de novo frameshift variant in the ASXL3 gene in a child with microcephaly and global developmental delay

Marketa Wayhelova, Jan Oppelt, Jan Smetana, Eva Hladilkova, Hana Filkova, Eva Makaturova, Petra Nikolova, Rastislav Beharka, Renata Gaillyova, Petr Kuglik
Pages: 505-512
Published online on: 27 May 2019

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Article Open Access

Comprehensive analysis of differentially expressed profiles of non‑coding RNAs in peripheral blood and ceRNA regulatory networks in non‑syndromic orofacial clefts

Yuwei Gao, Qiguang Zang, Hongquan Song, Songbin Fu, Wenjing Sun, Wei Zhang, Xiaotong Wang, Yong Li, Xiaohui Jiao
Pages: 513-528
Published online on: 22 May 2019

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Article Open Access

Salidroside protects SH‑SY5Y from pathogenic α‑synuclein by promoting cell autophagy via mediation of mTOR/p70S6K signaling

Shasha Chen, Feng Cai, Jirong Wang, Zhouxin Yang, Chi Gu, Guofu Wang, Genxiang Mao, Jing Yan
Pages: 529-538
Published online on: 23 May 2019

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Article Open Access

Combination of targeting CD24 and inhibiting autophagy suppresses the proliferation and enhances the apoptosis of colorectal cancer cells

Jingwei Zhuo, Xinying Wang
Pages: 539-548
Published online on: 23 May 2019

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Article Open Access

Bioinformatics analysis of the regulatory lncRNA‑miRNA‑mRNA network and drug prediction in patients with hypertrophic cardiomyopathy

Jiajianghui Li, Zining Wu, Deqiang Zheng, Yue Sun, Sisi Wang, Yuxiang Yan
Pages: 549-558
Published online on: 23 May 2019

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Article Open Access

Expression of transforming growth factor β and matrix metalloproteinases in the aqueous humor of patients with congenital ectopia lentis

Qianzhong Cao, Bing Xiao, Guangming Jin, Jianqiang Lin, Yiyao Wang, Charlotte Aimee Young, Junxiong Lin, Yijing Zhou, Bo Zhang, Mingzhe Cao, Kaili Wu, Danying Zheng
Pages: 559-566
Published online on: 23 May 2019

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Article Open Access

β‑catenin signalling inhibits cartilage endplate chondrocyte homeostasis in vitro

Lei Ding, Zengxin Jiang, Jingping Wu, Defang Li, Houlei Wang, Wei Lu, Qingmin Zeng, Guoxiong Xu
Pages: 567-572
Published online on: 27 May 2019

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Article Open Access

A 9‑lncRNA risk score system for predicting the prognosis of patients with hepatitis B virus‑positive hepatocellular carcinoma

Honghong Liu, Ping Zhao, Xueyuan Jin, Yanling Zhao, Yongqian Chen, Tao Yan, Jianjun Wang, Liang Wu, Yongqiang Sun
Pages: 573-583
Published online on: 22 May 2019

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Article Open Access

iTRAQ‑based proteomic analysis of endotoxin tolerance induced by lipopolysaccharide

Qian Zhang, Yingchun Hu, Jing Zhang, Cunliang Deng
Pages: 584-592
Published online on: 22 May 2019

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Evaluation of EGFR mutations in NSCLC with highly sensitive droplet digital PCR assays

Xi‑Wen Jiang, Wei Liu, Xiao‑Ya Zhu, Xiao‑Xie Xu
Pages: 593-603
Published online on: 21 May 2019

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miR‑221‑3p promotes the cell growth of non‑small cell lung cancer by targeting p27

Guoqing Yin, Bo Zhang, Jia Li
Pages: 604-612
Published online on: 23 May 2019

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Silencing of heat shock protein 27 increases the radiosensitivity of non‑small cell lung carcinoma cells

Liping Xu, Xuemei Lin, Yihua Zheng, Hua Zhou
Pages: 613-621
Published online on: 22 May 2019

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Characterization of a prognostic four‑gene methylation signature associated with radiotherapy for head and neck squamous cell carcinoma

Jiabao Ma, Rui Li, Jie Wang
Pages: 622-632
Published online on: 24 May 2019

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Comparison of biological characteristics of mesenchymal stem cells derived from the human umbilical cord and decidua parietalis

Yu‑Tao Guan, Yong Xie, Dong‑Sheng Li, Yu‑Yuan Zhu, Xiao‑Lu Zhang, Ying‑Lin Feng, Yang‑Ping Chen, Li‑Jiang Xu, Pin‑Fu Liao, Gang Wang
Pages: 633-639
Published online on: 23 May 2019

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Long intergenic non‑coding RNA 00467 promotes lung adenocarcinoma proliferation, migration and invasion by binding with EZH2 and repressing HTRA3 expression

Xianghai Wang, Hongbing Liu, Kaikai Shen, Xianhui Pan, Yuqing Wei, Tangfeng Lv, Yong Song
Pages: 640-654
Published online on: 23 May 2019

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Zinc supplementation inhibits the high glucose‑induced EMT of peritoneal mesothelial cells by activating the Nrf2 antioxidant pathway

Lili Gao, Yi Fan, Xiuli Zhang, Lina Yang, Wenyu Huang, Tianyu Hang, Mingyang Li, Shuyan Du, Jianfei Ma
Pages: 655-663
Published online on: 22 May 2019

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Substance P enhances BMSC osteogenic differentiation via autophagic activation

Wen Geng, Huimin Shi, Ximin Zhang, Wei Tan, Yuan Cao, Rongcheng Mei
Pages: 664-670
Published online on: 21 May 2019

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Construction and function of a fusion protein consisting of a single‑chain variable fragment and RBP4

Hongxia Li, Guangming Cao, Tong Lou, Zhenyu Zhang, Chongdong Liu
Pages: 671-677
Published online on: 22 May 2019

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Identification of CD4+ T cell biomarkers for predicting the response of patients with relapsing‑remitting multiple sclerosis to natalizumab treatment

Paolo Fagone, Emanuela Mazzon, Santa Mammana, Roberto Di Marco, Flaminia Spinasanta, Maria Sofia Basile, Maria Cristina Petralia, Placido Bramanti, Ferdinando Nicoletti, Katia Mangano
Pages: 678-684
Published online on: 23 May 2019

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The role and underlying mechanisms of microRNA‑214 in Legg‑Calvé‑Perthes disease Corrigendum in /10.3892/mmr.2019.10648

Hui Zhu, Xinyue Qi, Yuehe Liu, Wei Liao, Xiangshui Sun, Yuping Tang
Pages: 685-692
Published online on: 22 May 2019

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Identification of specific modules and significant genes associated with colon cancer by weighted gene co‑expression network analysis

Ye Feng, Yanbo Li, Lin Li, Xuefeng Wang, Zhi Chen
Pages: 693-700
Published online on: 24 May 2019

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LRG ameliorates steatohepatitis by activating the AMPK/mTOR/SREBP1 signaling pathway in C57BL/6J mice fed a high‑fat diet

Tao Hao, Hongying Chen, Sisi Wu, Haoming Tian
Pages: 701-708
Published online on: 28 May 2019

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Baicalin inhibits C2C12 myoblast apoptosis and prevents against skeletal muscle injury

Yutao Pan, Dongli Song, Weiyan Zhou, Xiuhong Lu, Haiyan Wang, Zengchun Li
Pages: 709-718
Published online on: 27 May 2019

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MicroRNA‑21 contributes to the puerarin‑induced cardioprotection via suppression of apoptosis and oxidative stress in a cell model of ischemia/reperfusion injury

Hai‑Xiang Xu, Wen Pan, Jian‑Feng Qian, Feng Liu, Hai‑Qi Dong, Qing‑Jun Liu
Pages: 719-727
Published online on: 22 May 2019

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Synergistic effect of kaempferol and 5‑fluorouracil on the growth of colorectal cancer cells by regulating the PI3K/Akt signaling pathway

Qiongyu Li, Lihui Wei, Shan Lin, Youqin Chen, Jiumao Lin, Jun Peng
Pages: 728-734
Published online on: 27 May 2019

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MicroRNA‑22 alleviates inflammation in ischemic stroke via p38 MAPK pathways

Huixiao Dong, Benliang Cui, Xiuzhen Hao
Pages: 735-744
Published online on: 22 May 2019

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RNA‑seq analyses of antibiotic resistance mechanisms in Serratia marcescens

Zhaodong Li, Meihua Xu, Hui Wei, Lili Wang, Min Deng
Pages: 745-754
Published online on: 22 May 2019

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c‑Jun N‑terminal kinase/transforming growth factor‑β/Smad3 pathway: Is it associated with endoplasmic reticulum stress‑mediated renal interstitial fibrosis?

Yuyuan Liu, Ping Shen, Yongmei Zhou, Li Tang, Huaqi Chai
Pages: 755-762
Published online on: 22 May 2019

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Protective effect of 3,5‑dicaffeoyl‑epi‑quinic acid against UVB‑induced photoaging in human HaCaT keratinocytes

Jung Hwan Oh, Fatih Karadeniz, Jung Im Lee, Youngwan Seo, Chang‑Suk Kong
Pages: 763-770
Published online on: 21 May 2019

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Effect of copper nanoparticles on brain cytochrome P450 enzymes in rats

Yanyan Wang, Huaqiao Tang, Min Xu, Jie Luo, Ling Zhao, Fei Shi, Gang Ye, Cheng Lv, Yinglun Li
Pages: 771-778
Published online on: 27 May 2019

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Reductions in gut microbiota‑derived metabolite trimethylamine N‑oxide in the circulation may ameliorate myocardial infarction‑induced heart failure in rats, possibly by inhibiting interleukin‑8 secretion

Xiaoyan Li, Yongcun Sun, Xinru Zhang, Jing Wang
Pages: 779-786
Published online on: 27 May 2019

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Overlapping of irritable bowel syndrome with erosive esophagitis and the performance of Rome criteria in diagnosing IBS in a clinical setting

Magdy El‑Salhy, Odd Helge Gilja, Jan Gunnar Hatlebakk
Pages: 787-794
Published online on: 23 May 2019

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miR‑148a modulates the viability, migration and invasion of oral squamous cell carcinoma cells by regulating HLA‑G expression

Yuying Zhang, Xin Jin, Jie Wang
Pages: 795-801
Published online on: 22 May 2019

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Callistephin enhances the protective effects of isoflurane on microglial injury through downregulation of inflammation and apoptosis

Lili Zhao, Shibiao Chen, Tianyin Liu, Xiuhong Wang, Haijin Huang, Weicheng Liu
Pages: 802-812
Published online on: 22 May 2019

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Effect of passaging on the stemness of infrapatellar fat pad‑derived stem cells and potential role of nucleostemin as a prognostic marker of impaired stemness

Subathra Radhakrishnan, Omana Anna Trentz, Catherine Ann Martin, Mettu Srinivas Reddy, Mohamed Rela, Marimuthu Chinnarasu, Narayana Kalkura, Shanmugaapriya Sellathamby
Pages: 813-829
Published online on: 22 May 2019

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Effect of macrophage migration inhibitory factor on inflammatory cytokines and fibrogenic gene expression in human RPE cells

Dong Qin, Yanrong Jiang, Xuemin Jin
Pages: 830-836
Published online on: 22 May 2019

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Bupivacaine at clinically relevant concentrations induces toxicity in human intervertebral disc cells via the induction of autophagy in vitro

Ge Yang, Zhuoyang Li, Haibo Mei, Weihua Ye, Shengxiang Huang, Kun Liu, Qian Tan
Pages: 837-843
Published online on: 22 May 2019

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June-2026 Volume 33 Issue 6

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Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

Mechanotransducer Piezo1 drives ventilator‑induced lung injury in lung epithelial cells via the calcineurin/NFATc3 pathway

Min Li, Shu-Li Zhang, Feng Yuan, Dan Feng
Article Number: 183
Published online on: 28 April 2026

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Oncogene c‑Myc: From molecular mechanism to targeted therapy (Review)

Jianjun Lu, Jing Zhu, Liqiong Zhang, Xiang Zheng, Shan Yang, Yatong Sang, Mingli Yang, Yu Tang
Article Number: 182
Published online on: 28 April 2026

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Indium (III) chloride inhibits testicular Leydig cell proliferation by disrupting centrosome copy numbers

Chia-Yih Wang, Ping-Jui Su, Kuan-Chih Wang, Ruei-Ci Lin, Min-Yun Ke, Yen-Ni Teng
Article Number: 181
Published online on: 28 April 2026

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Correction Open Access

[Corrigendum] Inhibition of DNA‑PK activity sensitizes A549 cells to X‑ray irradiation by inducing the ATM‑dependent DNA damage response

Lina Yang, Xinrui Yang, Yiwei Tang, Defu Zhang, Lijie Zhu, Shengnan Wang, Bo Wang, Tao Ma
Article Number: 180
Published online on: 27 April 2026

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Natural products and neurocognitive disorders: Mechanistic insights and research advances (Review)

Weiqing Li, Wei Wu, Xiaoqing Huang, Yinghai Liu, Gu Gong, Qingqing Huang
Article Number: 179
Published online on: 27 April 2026

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Research progress and future directions in circadian rhythms for uterine‑related diseases (Review)

Tiantian Ma, Junwei Li, Yi Fang, Tiancheng Xu, Qian Li, Liangjun Xia, Youbing Xia
Article Number: 178
Published online on: 27 April 2026

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Therapeutic potential of tertiary lymphoid structures in breast cancer (Review)

Liangxiao Zhu, Meigui Li, Feng Liu, Fenghou Gao
Article Number: 177
Published online on: 24 April 2026

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[Retracted] Prognostic and predictive roles of microRNA‑411 and its target STK17A in evaluating radiotherapy efficacy and their effects on cell migration and invasion via the p53 signaling pathway in cervical cancer

Wei Wei, Cun Liu
Article Number: 176
Published online on: 22 April 2026

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Insights into nuciferine: A natural multifunctional bioactive alkaloid (Review)

Yulin Liu, Xinye Li, Bo Huang, Xudong Lai, Baoqing Ye, Haixiong Miao, Lixian Zhang, Xifeng Xiong
Article Number: 175
Published online on: 22 April 2026

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Article

Urinary 8‑OHdG and MDA as rapid biodosimetry markers in the lethal/sublethal dose range

Satoru Monzen, Kenji Terada, Yusuke Tawata, Takanori Sato, Nozomi Kousaka, Yasushi Mariya
Article Number: 174
Published online on: 22 April 2026

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[Retracted] Treatment with harmine ameliorates functional impairment and neuronal death following traumatic brain injury  

Zeqi Zhong, Yuan Tao, Hui Yang
Article Number: 173
Published online on: 20 April 2026

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SRSF1 as a promising biomarker and key player in the pathogenesis of Alzheimer's disease

Yanchen Liu, Yi Zhao, Yanting Yao, Dan Liu, Yilei Sun, Weishi Xu, Hongli Yu, Lijun Chi
Article Number: 172
Published online on: 17 April 2026

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RUVBL1 and CRAF promote periodontal ligament stem cell osteogenic differentiation via the MEK/ERK signaling cascade

Xin-Yu Zhang, Peiqi Hao, Ming-Yue Qi, Hui Guo
Article Number: 171
Published online on: 16 April 2026

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Porphyromonas gingivalis triggers lipid metabolism disorders in atherosclerosis through the PPARγ-LXRα‑ABCA1/ABCG1 signaling pathway

Xue-Jing Lin, Min Yao, Wan-Yun Lin, Qin Yuan, Jie Zhou, Wen-Xuan Xia, Yu-Lei Dong, Miao-Miao Zhang, Ming-Wang Cui, Lin-Han Wu, Diwas Sunchuri, Muhammad Zia Ullah Shahid, Zhu-Ling Guo
Article Number: 170
Published online on: 16 April 2026

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[Corrigendum] MicroRNA‑122 acts as tumor suppressor by targeting TRIM29 and blocking the activity of PI3K/AKT signaling in nasopharyngeal carcinoma in vitro

Yan Yang, Qing Li, Lili Guo
Article Number: 169
Published online on: 15 April 2026

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Elevated IgG levels induce an M2‑to‑M1 phenotypic shift in mucosal macrophages and restrict the growth of invasive sphenoid sinus pituitary adenomas

Xingbo Li, Zhuowei Lei, Sihan Li, Linpeng Xu, Quanji Wang, Qian Jiang, Zihan Wang, Huaqiu Zhang, Yimin Huang, Ting Lei
Article Number: 168
Published online on: 14 April 2026

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[Retracted] SUMO1/UBC9‑decreased Nox1 activity inhibits reactive oxygen species generation and apoptosis in diabetic retinopathy

Jiaoli Hu, Pengcheng Xue, Xinbang Mao, Lin Xie, Guodong Li, Zhipeng You
Article Number: 167
Published online on: 14 April 2026

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Potential for anti‑angiogenic therapy targeting the receptor for advanced glycation end products/VEGF axis in ulcerative colitis (Review)

Chen Xu, Yuting Li, Yahua Hong, Dayong Zhou, Kun He, Lianghui Wang, Feng Hong
Article Number: 166
Published online on: 09 April 2026

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[Retracted] Molecular mechanisms underlying mangiferin‑induced apoptosis and cell cycle arrest in A549 human lung carcinoma cells

Wei Shi, Jiagang Deng, Rongsheng Tong, Yong Yang, Xia He, Jianzhen Lv, Hailian Wang, Shaoping Deng, Ping Qi, Dingding Zhang, Yi Wang
Article Number: 165
Published online on: 07 April 2026

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Mechanism of and research progress on alterations in the RET gene in thyroid cancer (Review)

Meng Wei, Rui Wang, Jincan Qian, Qiang Fang, Jun Tao
Article Number: 164
Published online on: 02 April 2026

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Current research progress on extracellular vesicles derived from mesenchymal stem cells in tuberculosis treatment (Review)

Dejun Fan, Yan Yang, Li Yang
Article Number: 163
Published online on: 01 April 2026

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Uremic toxin p‑cresyl sulfate enhances the calcification of aortic valvular interstitial cells via klotho/sirtuin‑1 signaling

Shao-Jung Li, Tzu-Yu Cheng, Yu-Hsun Kao, Wei-Yu Chen, Cheng-Chih Chung, Nguyen Ngoc Trang, Pao-Huan Chen, Yi-Jen Chen
Article Number: 162
Published online on: 01 April 2026

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Exercise‑induced extracellular vesicle microRNA regulates physiological function (Review)

Zhonglei Wang, Wenjue Guo, Haojia He, Yi Zhang, Na Li
Article Number: 161
Published online on: 01 April 2026

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Expression of Concern Open Access

[Expression of Concern] Electroacupuncture at GV20‑GB7 regulates mitophagy to protect against neurological deficits following intracerebral hemorrhage via inhibition of apoptosis

Ruiqiao Guan, Zhihao Li, Xiaohong Dai, Wei Zou, Xueping Yu, Hao Liu, Qiuxin Chen, Wei Teng, Peng Liu, Xiaoying Liu, Shanshan Dong
Article Number: 160
Published online on: 01 April 2026

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Emerging roles of POLR2L of RNA polymerase II dynamics and disease mechanisms (Review)

Beomwoo Lee, Changgyu Son, Sunho Eom, Yuwen Li, Seon-Hwan Kim, Jongsun Park
Article Number: 159
Published online on: 30 March 2026

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Combining bioinformatics prediction with experimental validation to explore the ameliorative effect of Psoralea corylifolia on vitiligo

Chen Zhang, Zhanhong Cao, Mengyang Wei, Xuanxuan Zhu, Yan Yan, Zhenhua Wang, Meng Zhang
Article Number: 158
Published online on: 30 March 2026

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[Retracted] All‑trans‑retinoic acid inhibits chondrogenesis of rat embryo hindlimb bud mesenchymal cells by down­regulating p53 expression

Tao-Gen Zhang, Xue-Dong Li, Guo-Yong Yu, Peng Xie, Yun-Guo Wang, Zhao-Yong Liu, Quan Hong, De-Zhong Liu, Shi-Xin Du
Article Number: 157
Published online on: 30 March 2026

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Journal Cover
July-2026 Volume 34 Issue 1

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Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

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Polysaccharides: Natural candidates for targeting immunometabolic regulation in hepatocellular carcinoma (Review)

Changmei Wu, Jinjin Dou, Xiwu Zhang
Article Number: 195
Published online on: 18 May 2026

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NF‑κB signaling drives Th17‑mediated lacrimal gland injury and tear dysfunction in a murine model of primary Sjögren's syndrome

Jiajun Xie, Huina Zhang, Wenyue Shen, Juan Ye
Article Number: 194
Published online on: 18 May 2026

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POSTN(+) fibroblasts and SPP1(+) macrophages in scar formation: A review of mechanisms and therapeutic targets (Review)

Haotian Wu, Xianglin Dong
Article Number: 193
Published online on: 15 May 2026

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Emerging role of DYRK1A as a target in cardiovascular diseases (Review)

Liqing Yu, Qionghong Cheng, Jun Wu
Article Number: 192
Published online on: 15 May 2026

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[Retracted] Resveratrol pretreatment attenuates traumatic brain injury in rats by suppressing NLRP3 inflammasome activation via SIRT1

Peng Zou, Xiaoxiao Liu, Gang Li, Yangang Wang
Article Number: 191
Published online on: 05 May 2026

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Gut microbiota and its metabolites: Key factors of drug resistance in the treatment of advanced prostate cancer (Review)

Jingheng Song, Hongguo Cui, Peisen Yang, Yankai Xu, Yuanyuan Liu, Gang Zhang, Yangyang Liu, Aimin Tian, Jizhong Che, Hui Sun, Zhengchao Zhang
Article Number: 190
Published online on: 04 May 2026

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Cepharanthine inhibits lysosomes and induces apoptosis in triple‑negative breast cancer cells

Juan Li, Siqin Zhou, Yu Wang, Guanghan Ou, Danli Yang, Liwen Shen
Article Number: 189
Published online on: 04 May 2026

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Applications of humanized mice in Mycobacterium tuberculosis infections (Review)

Binghua Han, Fang Liu, Jinzhao Long, Jiongjiong Wang, Yange Cui, Haiyan Yang
Article Number: 188
Published online on: 04 May 2026

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Research progress on neutrophil extracellular traps in sepsis‑induced coagulopathy (Review)

Jiandong Hu, Mengli Jin, Zhihua Cao, Binbin Zheng, Yuan Zheng, Hao Shen
Article Number: 187
Published online on: 04 May 2026

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Multifaceted regulatory role of proline‑ and glutamine-rich splicing factor in tumors (Review)

Shilin Zhang, Zhenhua Li, Li Fu
Article Number: 186
Published online on: 04 May 2026

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Effects of ALDH2 gene expression on the oxidative stress‑mediated NF‑κB/mTOR pathway in ketamine‑induced cystitis

Xiao Jian Xi, Yong Yao, Peng Gu, Min Hao Zhang
Article Number: 185
Published online on: 04 May 2026

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Retraction Open Access

[Retracted] Rosiglitazone exerts neuroprotective effects via the suppression of neuronal autophagy and apoptosis in the cortex following traumatic brain injury

Junchao Yao, Kebin Zheng, Xiang Zhang
Article Number: 184
Published online on: 29 April 2026

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