Journal Articles

Open Access

Overexpression of rhophilin 2 promotes pancreatic ductal adenocarcinoma

Wentao Bo, Xielin Feng, Xiaoli Tang

Article Number: 76 Published online on: 25 November 2020
Open Access

Circular dumbbell miR‑34a‑3p and ‑5p suppresses pancreatic tumor cell‑induced angiogenesis and activates macrophages

Manu Gnanamony, Lusine Demirkhanyan, Liang Ge, Paresh Sojitra, Sneha Bapana, Joseph A. Norton, Christopher S. Gondi

Article Number: 75 Published online on: 25 November 2020
Open Access

Prognosis of segmentectomy in the treatment of stage IA non‑small cell lung cancer (Review)

Wenliang Bai, Shanqing Li

Article Number: 74 Published online on: 25 November 2020
Open Access

Correlation analysis of serum cystatin C, uric acid and lactate dehydrogenase levels before chemotherapy on the prognosis of small‑cell lung cancer

Haocheng Wang, Dongfeng Shan, Ya Dong, Xue Yang, Linwei Zhang, Zhuang Yu

Article Number: 73 Published online on: 25 November 2020
Open Access

Villin is a biomarker for reverse polarity in colorectal micropapillary carcinoma

Li Zhao, Shao-Yan Liu, Yu-Meng Li, Zhong-Tang Xiong

Article Number: 72 Published online on: 25 November 2020
Open Access

Effective ferroptotic small-cell lung cancer cell death from SLC7A11 inhibition by sulforaphane

Yuko Iida, Mayumi Okamoto-Κatsuyama, Shuichiro Maruoka, Kenji Mizumura, Tetsuo Shimizu, Sotaro Shikano, Mari Hikichi, Mai Takahashi, Kota Tsuya, Shinichi Okamoto, Toshio Inoue, Yoko Nakanishi, Noriaki Takahashi, Shinobu Masuda, Shu Hashimoto, Yasuhiro Gon

Article Number: 71 Published online on: 25 November 2020
Open Access

Proliferation, migration and invasion of triple negative breast cancer cells are suppressed by berbamine via the PI3K/Akt/MDM2/p53 and PI3K/Akt/mTOR signaling pathways

Lili Liu, Jiadong Yan, Ying Cao, Yan Yan, Xiang Shen, Binbin Yu, Li Tao, Shusheng Wang

Article Number: 70 Published online on: 25 November 2020
Open Access

High expression of HVEM is associated with improved prognosis in intrahepatic cholangiocarcinoma

Bingqi Ma, Huijuan Meng, Ye Tian, Yingying Wang, Tianqiang Song, Ti Zhang, Qiang Wu, Yunlong Cui, Huikai Li, Wei Zhang, Qiang Li

Article Number: 69 Published online on: 25 November 2020
Open Access

Post‑radiation circulating tumor DNA as a prognostic factor in locally advanced esophageal squamous cell carcinoma

Ru Jia, Chuan-Hua Zhao, Pan-Song Li, Rong-Rui Liu, Yun Zhang, Hai-E Chen, Lian-Peng Chang, Yu-Hua Gong, Yan-Fang Guan, Xin Yi, Jian-Ming Xu

Article Number: 68 Published online on: 25 November 2020
Open Access

Lentiviral vector with a radiation‑inducible promoter, carrying the ING4 gene, mediates radiosensitization controlled by radiotherapy in cervical cancer cells

Tao Ma, Rui Guo, Xi Wang, Wen-Tong Shen, Min Zhu, Ye-Ning Jin, Hao-Ping Xu

Article Number: 67 Published online on: 25 November 2020
Open Access

Effects of matrine in combination with cisplatin on liver cancer

Gaoyu Hu, Cong Cao, Zhihua Deng, Jun Li, Xihan Zhou, Zansong Huang, Chao Cen

Article Number: 66 Published online on: 25 November 2020
Open Access

β‑hydroxybutyrate does not alter the effects of glucose deprivation on breast cancer cells

Rylee Maldonado, Chloe Adrienna Talana, Cassaundra Song, Alyssa Dixon, Kahealani Uehara, Michael Weichhaus

Article Number: 65 Published online on: 23 November 2020
Open Access

Histone deacetylase 6 inhibition in urothelial cancer as a potential new strategy for cancer treatment

Hiroo Kuroki, Tsutomu Anraku, Akira Kazama, Yuko Shirono, Vladimir Bilim, Yoshihiko Tomita

Article Number: 64 Published online on: 20 November 2020
Open Access

The expression of trefoil factor 3 is related to histologic subtypes and invasiveness in lung adenocarcinoma

Wenjuan Luo, Shinichiro Tahara, Keisuke Kawasaki, Ayaka Kobayashi, Satoshi Nojima, Eiichi Morii

Article Number: 63 Published online on: 19 November 2020
Open Access

Antitumour activity of TH1579, a novel MTH1 inhibitor, against castration‑resistant prostate cancer

Mingqiu Hu, Jing Ning, Likai Mao, Yuanyuan Yu, Yu Wu

Article Number: 62 Published online on: 19 November 2020
Open Access

Crizotinib changes the metabolic pattern and inhibits ATP production in A549 non‑small cell lung cancer cells

Sa Ye, Hong-Bin Zhou, Ying Chen, Kai-Qiang Li, Shan-Shan Jiang, Ke Hao

Article Number: 61 Published online on: 19 November 2020
Open Access

Identification of key genes in lung adenocarcinoma based on a competing endogenous RNA network

Zikun Song, Yinjiang Zhang, Zheren Chen, Bicheng Zhang

Article Number: 60 Published online on: 19 November 2020
Open Access

Antitumor effects of dioscin in A431 cells via adjusting ATM/p53‑mediated cell apoptosis, DNA damage and migration

Peng Wang, Chun Wang, Chunying Liu

Article Number: 59 Published online on: 19 November 2020
Open Access

Innate immune cells and their interaction with T cells in hepatocellular carcinoma (Review)

Guo-Qing Hong, Dong Cai, Jian-Ping Gong, Xing Lai

Article Number: 57 Published online on: 19 November 2020
Open Access

Soluble CD40 ligand inhibits the growth of non‑Hodgkin's lymphoma cells through the JNK signaling pathway

Zhongxin Feng, Jishi Wang

Article Number: 56 Published online on: 18 November 2020
Open Access

Downregulation of APRIN expression increases cancer cell proliferation via an interleukin-6/STAT3/cyclin D axis

Min-Shik Sohn, Miae Kang, Seong-Man Kang, Sangwoo Bae

Article Number: 55 Published online on: 18 November 2020
Open Access

Circulating exosomal miR‑125a‑5p as a novel biomarker for cervical cancer

Aixia Lv, Zengrong Tu, Yunhua Huang, Weiying Lu, Baoguo Xie

Article Number: 54 Published online on: 18 November 2020
Open Access

LINC00565 promotes the progression of colorectal cancer by upregulating EZH2

Xiaxia Shao, Tao Zhao, Lei Xi, Yuhong Zhang, Jia He, Jie Zeng, Lichun Deng

Article Number: 53 Published online on: 18 November 2020
Open Access

Nidogen 1 regulates proliferation and migration/invasion in murine claudin‑low mammary tumor cells

Rebecca Jagroop, Courtney J. Martin, Roger A. Moorehead

Article Number: 52 Published online on: 18 November 2020
Open Access

Integrated analysis of microRNA and transcription factors in the bone marrow of patients with acute monocytic leukemia

Xiao-Cong Lin, Qin Yang, Wei-Yu Fu, Liu-Bo Lan, Hang Ding, Yu-Ming Zhang, Ning Li, Hai-Tao Zhang

Article Number: 50 Published online on: 18 November 2020

Identification of an antitumor effect of demethylzeylasteral on human gastric cancer cells

Yang Yang, Menglin Zhao, Ting Hu, Fang Su, Feng Qian, Zishu Wang

Article Number: 49 Published online on: 18 November 2020
Open Access

Role of tesmin expression in non‑small cell lung cancer

Jedrzej Grzegrzolka, Mateusz Olbromski, Agnieszka Gomulkiewicz, Aleksandra Piotrowska, Natalia Glatzel‑Plucinska, Katarzyna Ratajczak, Patrycja Sputa‑Grzegrzolka, Adam Rzechonek, Bozena Werynska, Marzena Podhorska‑Okolow, Piotr Dziegiel

Article Number: 48 Published online on: 17 November 2020
Open Access

Fibrinogen‑like protein 2 promotes the accumulation of myeloid‑derived suppressor cells in the hepatocellular carcinoma tumor microenvironment

Bo-Qian Liu, Zhi-Ye Bao, Jia-Yi Zhu, Hao Liu

Article Number: 47 Published online on: 17 November 2020
Open Access

Abnormal expression of HNRNPA3 in multistep hepatocarcinogenesis

Xinlu Ren, Yi Dong, Miao Duan, Hui Zhang, Peng Gao

Article Number: 46 Published online on: 17 November 2020
Open Access

Overexpression of monocarboxylate transporter 4 promotes the migration and invasion of non‑carcinogenic L929 fibroblast cells

Xiangru Li, Xiaoju Zhou, Ying Liu, Jingjing Fan, Hongjing  Huo, Jingjing Yao, Lin Wang, Ningning Ma

Article Number: 44 Published online on: 17 November 2020
Open Access

Management of aggressive fibromatosis (Review)

Zhijun Zhang, Jian Shi, Tao Yang, Tongjun Liu, Kai Zhang

Article Number: 43 Published online on: 17 November 2020
Open Access

Identification of the potential roles of ring finger protein 8 in TP53‑mutant breast cancer

Feng Zhao, Peibin Wang, Yan Guo, Qi Lu, Xu Kong, Dongwei Su, Hengyu Li, Guoping Liu, Chaoqian Liu

Article Number: 42 Published online on: 17 November 2020
Open Access

High frequency of microsatellite instability and its substantial co‑existence with KRAS and BRAF mutations in Vietnamese patients with colorectal cancer

Ha Thi Nguyen, Do Thanh Le, Quan Hong Duong, Vinay Bharadwaj Tatipamula, Bang Van Nguyen

Article Number: 41 Published online on: 13 November 2020
Open Access

Overexpression of CTEN is associated with gefitinib resistance in non‑small cell lung cancer

Xiangdong Lu, Yao Zhang, Yukai Pan, Minmin Cao, Xie Zhou, Tingrong Zhang

Article Number: 40 Published online on: 13 November 2020
Open Access

Knockdown of UCA1 restrains cell proliferation and metastasis of diffuse large B‑cell lymphoma by counteracting miR‑331‑3p expression

Minqing Zhang, Yiping Du, Jingmei Shang, Dongqing Zhang, Xiaoqing Dong, Hong Chen

Article Number: 39 Published online on: 13 November 2020
Open Access

SDF1α/CXCR4 axis may be associated with the malignant progression of gastric cancer in the hypoxic tumor microenvironment

Masakazu Yashiro, Haruhito Kinoshita, Gen Tsujio, Tatsunari Fukuoka, Yurie Yamamoto, Tomohiro Sera, Atsushi Sugimoto, Sadaaki Nishimura, Shuhei Kushiyama, Shingo Togano, Kenji Kuroda, Takahiro Toyokawa, Masaichi Ohira

Article Number: 38 Published online on: 12 November 2020
Open Access

Expression levels of FBXW7 and MDM2 E3 ubiquitin ligases and their c‑Myc and p53 substrates in patients with dysplastic nevi or melanoma

Julija Mozuraitiene, Zivile Gudleviciene, Ieva Vincerzevskiene, Aida Laurinaviciene, Justinas Pamedys

Article Number: 37 Published online on: 12 November 2020
Open Access

CD204‑positive macrophages accumulate in breast cancer tumors with high levels of infiltrating lymphocytes and programmed death ligand‑1 expression

Mayuko Nagano, Kanako Saito, Yuji Kozuka, Masako Ichishi, Hiroto Yuasa, Aya Noro, Nao Imai, Mai Shibusawa, Mao Kimoto, Makoto Ishitobi, Yasutaka Tono, Hiroyasu Oda, Mikiya Ishihara, Toshiro Mizuno, Tomoko Ogawa, Naoyuki Katayama

Article Number: 36 Published online on: 12 November 2020
Open Access

MicroRNA‑126: A new and promising player in lung cancer (Review)

Qijun Chen, Shuanghua Chen, Juanjuan Zhao, Ya Zhou, Lin Xu

Article Number: 35 Published online on: 12 November 2020
Open Access

Pancreatic cancer cell apoptosis is induced by a proteoglycan extracted from Ganoderma lucidum

Xiao Wu, Liping Jiang, Zeng Zhang, Yanming He, Yilong Teng, Jiaqi Li, Shilin Yuan, Yanna Pan, Haohui Liang, Hongjie Yang, Ping Zhou

Article Number: 34 Published online on: 12 November 2020
Open Access

miR‑4636 inhibits tumor cell proliferation, migration and invasion, and serves as a candidate clinical biomarker for gastric cancer

Jiaying Tang, Ying Hu, Chunjie Zhang, Cuixue Gong

Article Number: 33 Published online on: 12 November 2020
Open Access

Autophagy and apoptosis induction by sesamin in MOLT‑4 and NB4 leukemia cells

Kamolchanok Deesrisak, Chawalit Chatupheeraphat, Sittiruk Roytrakul, Usanarat Anurathapan, Dalina Tanyong

Article Number: 32 Published online on: 12 November 2020
Open Access

Metformin inhibits epithelial‑mesenchymal transition of oral squamous cell carcinoma via the mTOR/HIF‑1α/PKM2/STAT3 pathway

Weihuang Yin, Yang Liu, Xinchen Liu, Xiaozhou Ma, Bin Sun, Ziying Yu

Article Number: 31 Published online on: 11 November 2020
Open Access

Cathepsin B is highly expressed in pancreatic cancer stem‑like cells and is associated with patients' surgical outcomes

Takuya Fujimoto, Ryouichi Tsunedomi, Satoshi Matsukuma, Kiyoshi Yoshimura, Atsunori Oga, Nobuyuki Fujiwara, Yasuhiro Fujiwara, Hiroto Matsui, Yoshitaro Shindo, Yukio Tokumitsu, Nobuaki Suzuki, Shogo Kobayashi, Shoichi Hazama, Hidetoshi Eguchi, Hiroaki Nagano

Article Number: 30 Published online on: 11 November 2020
Open Access

Prognostic significance of an autophagy‑related long non‑coding RNA signature in patients with oral and oropharyngeal squamous cell carcinoma

Qingkun Jiang, Danfeng Xue, Fanzhe Shi, Jiaxuan Qiu

Article Number: 29 Published online on: 11 November 2020
Open Access

Inhibitor for protein disulfide‑isomerase family A member 3 enhances the antiproliferative effect of inhibitor for mechanistic target of rapamycin in liver cancer: An in vitro study on combination treatment with everolimus and 16F16

Yohei Kaneya, Hideyuki Takata, Ryuichi Wada, Shoko Kure, Kousuke Ishino, Mitsuhiro Kudo, Ryota Kondo, Nobuhiko Taniai, Ryuji Ohashi, Hiroshi Yoshida, Zenya Naito

Article Number: 28 Published online on: 11 November 2020
Open Access

Fatty acid synthase promotes breast cancer metastasis by mediating changes in fatty acid metabolism

Shuo Xu, Tingting Chen, Lihua Dong, Tao Li, Hui Xue, Bo Gao, Xiaodong Ding, Hui Wang, Hua Li

Article Number: 27 Published online on: 11 November 2020
Open Access

Downregulation of histone‑lysine N‑methyltransferase EZH2 inhibits cell viability and enhances chemosensitivity in lung cancer cells

Ziyang Cao, Wei Wu, Haiting Wei, Wei Zhang, Yan Huang, Zhengwei Dong

Article Number: 26 Published online on: 11 November 2020
Open Access

Polyphyllin VII suppresses cell proliferation, the cell cycle and cell migration in colorectal cancer

Cheng Song, Bo Pan, Xiao Yang, Wei Tang

Article Number: 25 Published online on: 11 November 2020
Open Access

Potentiating activities of chrysin in the therapeutic efficacy of 5‑fluorouracil in gastric cancer cells

Sunyi Lee, Suk Kyeong Lee, Joohee Jung

Article Number: 24 Published online on: 11 November 2020
Open Access

Regulation of microRNA‑497 expression in human cancer (Review)

Guanshui Luo, Ke He, Zhenglin Xia, Shuai Liu, Hong Liu, Guoan Xiang

Article Number: 23 Published online on: 11 November 2020
Open Access

Thrombospondin‑1 is a prognostic biomarker and is correlated with tumor immune microenvironment in glioblastoma

Chunxiao Qi, Lei Lei, Jinqu Hu, Gang Wang, Jiyuan Liu, Shaowu Ou

Article Number: 22 Published online on: 09 November 2020
Open Access

ERα increases endometrial cancer cell resistance to cisplatin via upregulation of BAG3

Shuetsu Abe, Masahiro Iwasaki, Shutaro Habata, Tasuku Mariya, Masato Tamate, Motoki Matsuura, Seiro Satohisa, Tsuyoshi Saito

Article Number: 20 Published online on: 09 November 2020
Open Access

Epithelial‑mesenchymal transition and metastatic ability of CD133+ colorectal cancer stem‑like cells under hypoxia

Masamichi Okada, Kazushige Kawai, Hirofumi Sonoda, Hiroshi Shiratori, Junko Kishikawa, Hiroshi Nagata, Hiroaki Nozawa, Kazuhito Sasaki, Manabu Kaneko, Koji Murono, Shigenobu Emoto, Yuuki Iida, Hiroaki Ishii, Yuichiro Yokoyama, Hiroyuki Anzai, Kiyoshi Hasegawa, Soichiro Ishihara

Article Number: 19 Published online on: 09 November 2020
Open Access

Network pharmacological systems study of Huang‑Lian‑Tang in the treatment of glioblastoma multiforme

Wangrui Liu, Wenhao Xu, Chuanyu Li, Junfei Xu, Ke Huang, Renyue Hu, Haineng Huang, Xiaojuan Liu

Article Number: 18 Published online on: 06 November 2020
Open Access

Multiple functions of TBCK protein in neurodevelopment disorders and tumors (Review)

Jin Wu, Guanting Lu

Article Number: 17 Published online on: 06 November 2020
Open Access

TERT promoter regulating melittin expression induces apoptosis and G0/G1 cell cycle arrest in esophageal carcinoma cells

Chao Zhou, Jie Ma, Yuanhua Lu, Wan Zhao, Bingxue Xu, Jian Lin, Yongjun Ma, Yafei Tian, Qi Zhang, Wei Wang, Weiqun Yan, Ping Jiao

Article Number: 16 Published online on: 06 November 2020
Open Access

KRAS and NRAS mutation detection in circulating DNA from patients with metastatic colorectal cancer using BEAMing assay: Concordance with standard biopsy and clinical evaluation

Elena Lastraioli, Lorenzo Antonuzzo, Beatrice Fantechi, Luisa Di Cerbo, Alessandro Di Costanzo, Daniele Lavacchi, Miriam Armenio, Annarosa Arcangeli, Francesca Castiglione, Luca Messerini, Francesco Di Costanzo

Article Number: 15 Published online on: 06 November 2020
Open Access

The mechanism of and the association between interleukin‑27 and chemotherapeutic drug sensitivity in lung cancer

Bingdong Jiang, Wenbo Shi, Peng Li, Yanli Wu, Yun Li, Chuanming Bao

Article Number: 14 Published online on: 06 November 2020
Open Access

Inhibition of proliferation and migration and induction of apoptosis in glioma cells by silencing TLR4 expression levels via RNA interference

Yingzi Liu, Yingchao Ju, Jianghui Liu, Yuetong Chen, Xiangran Huo, Liang Liu

Article Number: 13 Published online on: 06 November 2020
Open Access

[Corrigendum] Impact of microRNA‑29b on natural killer cells in T‑cell acute lymphoblastic leukemia

Fengyan Jin, Zhonghua Du, Yang Tang, Lixia Wang, Yanping Yang

Article Number: 12 Published online on: 05 November 2020

Plasma plastin‑3: A tumor marker in patients with non‑small‑cell lung cancer treated with nivolumab

Kengo Kuriyama, Takehiko Yokobori, Makoto Sohda, Nobuhiro  Nakazawa, Toshiki  Yajima, Ichiro Naruse, Hiroyuki  Kuwano, Ken Shirabe, Kyoichi Kaira, Hiroshi Saeki

Article Number: 11 Published online on: 03 November 2020
Open Access

Siglec-7 is a predictive biomarker for the efficacy of cancer vaccination against metastatic colorectal cancer

Kensuke Yamada, Shoichi Hazama, Nobuaki Suzuki, Ming Xu, Yuki Nakagami, Nobuyuki Fujiwara, Ryouichi Tsunedomi, Shin Yoshida, Shinobu Tomochika, Satoshi Matsukuma, Hiroto Matsui, Yukio Tokumitsu, Shinsuke Kanekiyo, Yoshitaro Shindo, Yusaku Watanabe, Michihisa Iida, Shigeru Takeda, Tatsuya Ioka, Tomio Ueno, Hiroyuki Ogihara, Yoshihiko Hamamoto, Yoshinobu Hoshii, Hiroo Kawano, Tomonobu Fujita, Yutaka Kawakami, Hiroaki Nagano

Article Number: 10 Published online on: 03 November 2020
Open Access

Molecular characteristics of uveal melanoma and intraocular tumors (Review)

Periklis Katopodis, Mohammad S. Khalifa, Vladimir Anikin

Article Number: 9 Published online on: 03 November 2020
Open Access

Aberrant methylation of GADD45A is associated with decreased radiosensitivity in cervical cancer through the PI3K/AKT signaling pathway

Meng Lou, Rong Li, Ting-Yuan Lang, Li-Ying Zhang, Qi Zhou, Li Li

Article Number: 8 Published online on: 03 November 2020

Long‑term model of colitis‑associated colorectal cancer suggests tumor spread mechanism and nature of cancer stem cells

Yuji Tanimura, Toshiro Fukui, Shunsuke Horitani, Yasushi Matsumoto, Sachi Miyamoto, Ryo Suzuki, Toshihiro Tanaka, Takashi Tomiyama, Tsukasa Ikeura, Yugo Ando, Akiyoshi Nishio, Kazuichi Okazaki

Article Number: 7 Published online on: 03 November 2020
Open Access

Blockade of TRIM59 enhances esophageal cancer cell chemosensitivity to cisplatin by upregulating p53

Rongfeng Liu, Hongchen Li, Yanzhao Xu, Xing Li, Xiaojin Guo, Jian Shi, Yanzhi Cui, Zhiyu Wang, Junfeng Liu

Article Number: 6 Published online on: 03 November 2020

Overexpression of microRNA‑124‑5p sensitizes non‑small cell lung cancer cells to treatment with 5‑fluorouracil via AEG‑1 regulation

Xiaoxia Tan, Chuancui Zhang, Weidong Gao, Bei Sun, Baozhen Jiang, Peng Song

Article Number: 5 Published online on: 03 November 2020
Open Access

Altered expression of microRNA‑92b‑3p predicts survival outcomes of patients with prostate cancer and functions as an oncogene in tumor progression

Gang Wang, Bo Cheng, Renfeng Jia, Bo Tan, Wenlong Liu

Article Number: 4 Published online on: 03 November 2020
Open Access

Cell‑free DNA as a liquid biopsy for early detection of gastric cancer (Review)

Zheng-Bin Huang, Hai-Tao Zhang, Benjamin Yu, De-Hua Yu

Article Number: 3 Published online on: 03 November 2020
Open Access

Clinical significance of interleukin‑10 concentration in the cerebrospinal fluid of patients with primary central nervous system lymphoma

Mingying Geng, Yang Song, He Xiao, Zhiyu Wu, Xiaojuan Deng, Chuan Chen, Ge Wang

Article Number: 2 Published online on: 03 November 2020
Open Access

Roles of ten‑eleven translocation family proteins and their O‑linked β‑N‑acetylglucosaminylated forms in cancer development (Review)

Hong-Jiao Li, Yi Wang, Bing-Xin Li, Yang Yang, Feng  Guan, Xing-Chen Pang, Xiang Li

Article Number: 1 Published online on: 03 November 2020
Journal Cover

January-2021
Volume 21 Issue 1

Print ISSN: 1792-1074
Online ISSN: 1792-1082

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