Journal Articles

Review

Targeted molecular therapies for ovarian cancer: an update and future perspectives (Review)

Hiroshi Shigetomi, Yumi Higashiura, Hirotaka Kajihara, Hiroshi Kobayashi

Pages: 395-408 Published online on: 25 May 2012
Review

Emerging biomarkers of prostate cancer (Review)

Sarah K. Martin, Taylor B. Vaughan, Timothy Atkinson, Haining Zhu, Natasha Kyprianou

Pages: 409-417 Published online on: 25 May 2012
Review

Correlation of the risk of breast cancer and disruption of the circadian rhythm (Review)

Giulia Costanza Leonardi, Venerando Rapisarda, Andrea Marconi, Aurora Scalisi, Francesca Catalano, Lidia Proietti, Salvo Travali, Massimo Libra, Concettina Fenga

Pages: 418-428 Published online on: 29 May 2012
Article Open Access

Comparison of tear protein levels in breast cancer patients and healthy controls using a de novo proteomic approach

Daniel Böhm, Ksenia Keller, Julia Pieter, Nils Boehm, Dominik Wolters, Wulf Siggelkow, Antje Lebrecht, Marcus Schmidt, Heinz Kölbl, Norbert Pfeiffer, Franz-Hermann Grus

Pages: 429-438 Published online on: 01 June 2012
Article Open Access

Enhanced anti-tumor and anti-angiogenic effects of metronomic cyclophosphamide combined with Endostar in a xenograft model of human lung cancer

Rui Wang, Shukui Qin, Yuqing Chen, Yumei Li, Changjie Chen, Zishu Wang, Rongsheng Zheng, Qiong Wu

Pages: 439-445 Published online on: 22 May 2012
Article Open Access

Trimodality therapy of esophagectomy plus neoadjuvant chemoradiotherapy improves the survival of clinical stage II/III esophageal squamous cell carcinoma patients

Yoshinori Fujiwara, Reigetsu Yoshikawa, Norihiko Kamikonya, Tsuyoshi Nakayama, Kotaro Kitani, Masanori Tsujie, Masao Yukawa, Masatoshi Inoue, Takehira Yamamura

Pages: 446-452 Published online on: 01 June 2012
Article

Circulating myeloid-derived suppressor cells are increased and correlate to immune suppression, inflammation and hypoproteinemia in patients with cancer

Shinji Ohki, Masahiko Shibata, Kenji Gonda, Takeshi Machida, Tatsuo Shimura, Izumi Nakamura, Toru Ohtake, Yoshihisa Koyama, Shinichi Suzuki, Hitoshi Ohto, Seiichi Takenoshita

Pages: 453-458 Published online on: 14 May 2012
Article

Tropism between hepatic and pulmonary metastases in colorectal cancers

Sung-Hyun Kim, So-Jung Choi, Joon Suk Park, Jinseon Lee, Yong Beom Cho, Min-Woong Kang, Woo Yong Lee, Yong Soo Choi, Hong Kwan Kim, Joungho Han, Ho-Kyung Chun, Jhingook Kim

Pages: 459-464 Published online on: 29 May 2012
Article

CD47 expression regulated by the miR-133a tumor suppressor is a novel prognostic marker in esophageal squamous cell carcinoma

Shigemasa Suzuki, Takehiko Yokobori, Naritaka Tanaka, Makoto Sakai, Akihiko Sano, Takanori Inose, Makoto Sohda, Masanobu Nakajima, Tatsuya Miyazaki, Hiroyuki Kato, Hiroyuki Kuwano

Pages: 465-472 Published online on: 24 May 2012
Article

Alterations of the base excision repair gene MUTYH in sporadic colorectal cancer

Takashi Kuno, Nagahide Matsubara, Satoshi Tsuda, Masayoshi Kobayashi, Mie Hamanaka, Daisuke Yamagishi, Kiyoshi Tsukamoto, Tomoki Yamano, Masafumi Noda, Hiroki Ikeuchi, Sanghyuk Kim, Kazuo Tamura, Naohiro Tomita

Pages: 473-480 Published online on: 25 May 2012
Article

Effects of low-intensity pulsed ultrasound on osteosarcoma and cancer cells

Yasushi Sawai, Hiroaki Murata, Kazutaka Koto, Takaaki Matsui, Naoyuki Horie, Eishi Ashihara, Taira Maekawa, Shinji Fushiki, Toshikazu Kubo

Pages: 481-486 Published online on: 17 May 2012
Article

Phase II study of neoadjuvant chemotherapy with irinotecan hydrochloride and nedaplatin followed by radical hysterectomy for bulky stage Ib2 to IIb, cervical squamous cell carcinoma: Japanese Gynecologic Oncology Group study (JGOG 1065)

Satoshi Yamaguchi, Ryuichiro Nishimura, Nobuo Yaegashi, Kazushige Kiguchi, Toru Sugiyama, Tsunekazu Kita, Kaneyuki Kubushiro, Katsuji Kokawa, Masamichi Hiura, Katsumi Mizutani, Kaichiro Yamamoto, Ken Takizawa

Pages: 487-493 Published online on: 14 May 2012
Article

Translocation of HSP27 into liver cancer cell nucleus may be associated with phosphorylation and O-GlcNAc glycosylation

Kun Guo, Lin Gan, Shu Zhang, Feng Jie Cui, Wang Cun, Yan Li, Nan Xiao Kang, Mei Dong Gao, Kun Yin Liu

Pages: 494-500 Published online on: 01 June 2012
Article

DLC2/StarD13 plays a role of a tumor suppressor in astrocytoma

Sally El-Sitt, Bassem D. Khalil, Samer Hanna, Marwan El-Sabban, Najla Fakhreddine, Mirvat El-Sibai

Pages: 511-518 Published online on: 17 May 2012
Article

Combined effects of EGFR and Hedgehog signaling pathway inhibition on the proliferation and apoptosis of pancreatic cancer cells

Chang-Fu Qin, Kun Hao, Xiao-Dong Tian, Xue-Hai Xie, Yin-Mo Yang

Pages: 519-526 Published online on: 09 May 2012
Article

Characterization of giant marker and ring chromosomes in a pleomorphic leiomyosarcoma of soft tissue by spectral karyotyping

Jun Nishio, Mikiko Aoki, Kazuki Nabeshima, Hiroshi Iwasaki, Masatoshi Naito

Pages: 533-538 Published online on: 25 May 2012
Article

5-Aza-2'-deoxycytidine induces cytotoxicity in BGC-823 cells via DNA methyltransferase 1 and 3a independent of p53 status

Juan Liu, Yan Zhang, Yi-Shan Xie, Fu-Liang Wang, Li-Jun Zhang, Tao Deng, He-Sheng Luo

Pages: 545-552 Published online on: 29 May 2012
Article

Cooperation of protease-activated receptor 1 and integrin ανβ5 in thrombin-mediated lung cancer cell invasion

Lingyun Zhu, Xiudong Wang, Jie Wu, Dekui Mao, Zhishan Xu, Ziyang He, Aiping Yu

Pages: 553-560 Published online on: 01 June 2012
Article

Notch inhibition suppresses nasopharyngeal carcinoma by depleting cancer stem-like side population cells

Shudong Yu, Ruxin Zhang, Fenye Liu, Hong Wang, Jing Wu, Yanqing Wang

Pages: 561-566 Published online on: 24 May 2012
Article

TGF-β autocrine pathway and MAPK signaling promote cell invasiveness and in vivo mammary adenocarcinoma tumor progression

María Cecilia Daroqui, Paula Vazquez, Elisa Bal de Kier Joffé, Andrei V. Bakin, Lydia I. Puricelli

Pages: 567-575 Published online on: 14 May 2012
Article

Selenium enhances the efficacy of Radachlorin mediated-photodynamic therapy in TC-1 tumor development

Yong-Wan Kim, Su Mi Bae, Hai-Bo Liu, In-Wook Kim, Heung-Jae Chun, Woong Shick Ahn

Pages: 576-584 Published online on: 17 May 2012
Article

Multiplexed bead-based immunoassay of four serum biomarkers for diagnosis of ovarian cancer

Yong-Wan Kim, Su Mi Bae, In-Wook Kim, Hai-Bo Liu, Hyo Joo Bang, Pankaj Kumar Chaturvedi, Gantumur Battogtokh, Hyunsun Lim, Woong Shick Ahn

Pages: 585-591 Published online on: 22 May 2012
Article

Altered microRNA expression in cisplatin-resistant ovarian cancer cells and upregulation of miR-130a associated with MDR1/P-glycoprotein-mediated drug resistance

Lingyun Yang, Ningwei Li, Hongjing Wang, Xibiao Jia, Xue Wang, Juan Luo

Pages: 592-600 Published online on: 18 May 2012
Article

Wogonin potentiates cisplatin-induced cancer cell apoptosis through accumulation of intracellular reactive oxygen species

Fan He, Qiong Wang, Xue-Lian Zheng, Jia-Qi Yan, Lan Yang, Hong Sun, Li-Na Hu, Yong Lin, Xia Wang

Pages: 601-605 Published online on: 31 May 2012
Article

TGF-β of lung cancer microenvironment upregulates B7H1 and GITRL expression in dendritic cells and is associated with regulatory T cell generation

Xiao Yan Ni, Hua Xiu Sui, Yao Liu, Shi Zhong Ke, Yi Nan Wang, Feng Guang Gao

Pages: 615-621 Published online on: 18 May 2012
Article

Rap1GAP alters leukemia cell differentiation, apoptosis and invasion in vitro

Tingting Qiu, Xiaofei Qi, Jiannong Cen, Zixing Chen

Pages: 622-628 Published online on: 18 May 2012
Article

shRNA targeting Bmi1 impedes the self-renewal of cisplatin-enriched stem-like cells in human A549 cells

Yu Xu, Yi-De Hu, Jing Zhou, Ming-Hui Zhang, Wei-Wei Yuan, Yan Luo

Pages: 629-639 Published online on: 01 June 2012
Article

Synergistic effect of malathion and estrogen on mammary gland carcinogenesis

Gloria M. Calaf, Carlos Echiburú-Chau

Pages: 640-646 Published online on: 17 May 2012
Article

Isogeneic comparison of primary and metastatic lung cancer identifies CX3CR1 as a molecular determinant of site-specific metastatic diffusion

Francesco A. Mauri, David J. Pinato, Pritesh Trivedi, Rohini Sharma, Robert J. Shiner

Pages: 647-653 Published online on: 17 May 2012
Article

Predictive value of the MGMT promoter methylation status in metastatic melanoma patients receiving first-line temozolomide plus bevacizumab in the trial SAKK 50/07

Peter Schraml, Adriana von Teichman, Daniela Mihic-Probst, Mathew Simcock, Adrian Ochsenbein, Reinhard Dummer, Olivier Michielin, Bettina Seifert, Marc Schläppi, Holger Moch, Roger von Moos

Pages: 654-658 Published online on: 18 May 2012
Article

Downregulation of IRS-1 promotes metastasis of head and neck squamous cell carcinoma

Xuan Luo, Songqing Fan, Wenbin Huang, Sulan Zhai, Zhuo Ma, Ping Li, Shi-Yong Sun, Xuerong Wang

Pages: 659-667 Published online on: 01 June 2012
Article

Efficient inhibition of ovarian cancer by recombinant CXC chemokine ligand 10 delivered by novel biodegradable cationic heparin-polyethyleneimine nanogels

Fan Yang, Malin Gou, Hongxin Deng, Tao Yi, Qian Zhong, Yuquan Wei, Xia Zhao

Pages: 668-676 Published online on: 06 June 2012
Article

4-hexylresorcinol stimulates the differentiation of SCC-9 cells through the suppression of E2F2, E2F3 and Sp3 expression and the promotion of Sp1 expression

Seong-Gon Kim, An-Sook Kim, Jae-Hwan Jeong, Je-Yong Choi, HaeYong Kweon

Pages: 677-681 Published online on: 01 June 2012
Article

Unique antineoplastic profile of Saquinavir-NO, a novel NO-derivative of the protease inhibitor Saquinavir, on the in vitro and in vivo tumor formation of A375 human melanoma cells

Marco Donia, Katia Mangano, Paolo Fagone, Rocco De Pasquale, Franco Dinotta, Marinella Coco, Julio Padron, Yousef Al-Abed, Giuseppe Angelo Giovanni Lombardo, Danijela Maksimovic-Ivanic, Sanja Mijatovic, Mai-Britt Zocca, Vincenzo Perciavalle, Stanislava Stosic-Grujicic, Ferdinando Nicoletti

Pages: 682-688 Published online on: 29 May 2012
Article

CC chemokine ligand 7 expression in liver metastasis of colorectal cancer

Yong Beom Cho, Woo Yong Lee, So-Jung Choi, Jhingook Kim, Hye Kyung Hong, Seok-Hyung Kim, Yoon-La Choi, Hee Cheol Kim, Seong Hyeon Yun, Ho-Kyung Chun, Kuhn Uk Lee

Pages: 689-694 Published online on: 14 May 2012
Article
Article

MicroRNA-1 and microRNA-499 downregulate the expression of the ets1 proto-oncogene in HepG2 cells

Wei Wei, Zheng Hu, Hanjing Fu, Yi Tie, Haihong Zhang, Yongge Wu, Xiaofei Zheng

Pages: 701-706 Published online on: 01 June 2012
Article

Regulated chemokine gene expression in mouse mesothelioma and mesothelial cells: TNF-α upregulates both CC and CXC chemokine genes

Simon A. Fox, Suzanne S. Loh, Sathish K. Mahendran, Michael J. Garlepp

Pages: 707-713 Published online on: 10 May 2012
Article

Loss of 15-hydroxyprostaglandin dehydrogenase indicates a tumor suppressor role in pituitary adenomas

Ji-Wei Bai, Zhe Wang, Song-Bai Gui, Ya-Zhuo Zhang

Pages: 714-720 Published online on: 09 May 2012
Article

Efficacy and safety of first-line erlotinib in elderly patients with advanced non-small cell lung cancer

Ofer Merimsky, Chi-Kin Cheng, Joseph Siu-Kie Au, Joachim von Pawel, Martin Reck

Pages: 721-727 Published online on: 18 May 2012
Article

Overexpression of the RD RNA binding protein in hepatitis C virus-related hepatocellular carcinoma

Michihisa Iida, Norio Iizuka, Ryouichi Tsunedomi, Masahiro Tsutsui, Shin Yoshida, Yoshinari Maeda, Yoshihiro Tokuhisa, Kazuhiko Sakamoto, Kiyoshi Yoshimura, Takao Tamesa, Masaaki Oka

Pages: 728-734 Published online on: 18 May 2012
Article

31P-Magnetic resonance spectra of ovarian cancer cells exposed to chemotherapy within a three-dimensional Matrigel construct

Yoram Abramov, Shani Carmi, Jack S. Cohen, Shaoul O. Anteby, Israel Ringel

Pages: 735-741 Published online on: 10 May 2012
Article

Water extract of Hedyotis Diffusa Willd suppresses proliferation of human HepG2 cells and potentiates the anticancer efficacy of low-dose 5-fluorouracil by inhibiting the CDK2-E2F1 pathway

Xu-Zheng Chen, Zhi-Yun Cao, Tuan-Sheng Chen, You-Quan Zhang, Zhi-Zhen Liu, Yin-Tao Su, Lian-Ming Liao, Jian Du

Pages: 742-748 Published online on: 25 May 2012
Article

Arsenic trioxide induces human pulmonary fibroblast cell death via increasing ROS levels and GSH depletion

Bo Ra You, Woo Hyun Park

Pages: 749-757 Published online on: 06 June 2012
Journal Cover

August 2012
Volume 28 Issue 2

Print ISSN: 1021-335X
Online ISSN: 1791-2431

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