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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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International Journal of Molecular Medicine

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
June-2014 Volume 33 Issue 6

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Molecular strategies for detecting chromosomal translocations in soft tissue tumors (Review)

Margherita Cerrone, Monica Cantile, Francesca Collina, Laura Marra, Giuseppina Liguori, Renato Franco, Annarosaria De Chiara, Gerardo Botti
Pages: 1379-1391
Published online on: 04 April 2014

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Review

Neuro-immune modulation of the thymus microenvironment (Review)

Fiorenzo Mignini, Maurizio Sabbatini, Laura Mattioli, Monica Cosenza, Marco Artico, Carlo Cavallotti
Pages: 1392-1400
Published online on: 20 March 2014

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Review

Perspectives on the therapeutic modulation of an alternative cell death, programmed necrosis (Review)

Young Sik Cho
Pages: 1401-1406
Published online on: 27 March 2014

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Article Open Access

miR-139-5p modulates cortical neuronal migration by targeting Lis1 in a rat model of focal cortical dysplasia

Yanjun Huang, Jiao Jiang, Guo Zheng, Jing Chen, Haiying Lu, Hu Guo, Chunfeng Wu
Pages: 1407-1414
Published online on: 18 March 2014

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Article Open Access

Molecular cloning, modeling and differential expression of a gene encoding a silent information regulator-like protein from Sporothrix schenckii

Binbin Hou, Xiaoming Liu, Fangliang Zheng, Xuezhu Xu, Zhenying Zhang
Pages: 1415-1422
Published online on: 31 March 2014

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Article Open Access

Tandem alternative polyadenylation events of genes in non-eosinophilic nasal polyp tissue identified by high-throughput sequencing analysis

Peng Tian, Jie Li, Xiang Liu, Yuxi Li, Meiheng Chen, Yun Ma, Yi Qing Zheng, Yonggui Fu, Hua Zou
Pages: 1423-1430
Published online on: 07 April 2014

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Article Open Access

TNF-α promotes gallbladder cancer cell growth and invasion through autocrine mechanisms

Guangwei Zhu, Qiang Du, Xiaoqian Wang, Nanhong Tang, Feifei She, Yanling Chen
Pages: 1431-1440
Published online on: 24 March 2014

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Article Open Access

Involvement of the SATB1/F-actin complex in chromatin reorganization during active cell death

Dariusz Grzanka, Maciej Gagat, Magdalena Izdebska
Pages: 1441-1450
Published online on: 21 March 2014

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Article Open Access

Celecoxib regulates apoptosis and autophagy via the PI3K/Akt signaling pathway in SGC-7901 gastric cancer cells

Min Liu, Chun-Mei Li, Zhao-Feng Chen, Ri Ji, Qing-Hong Guo, Qiang Li, Hong-Ling Zhang, Yong-Ning Zhou
Pages: 1451-1458
Published online on: 27 March 2014

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Article Open Access

High expression of β3GnT8 is associated with the metastatic potential of human glioma

Jun Liu, Li Shen, Lingyan Yang, Shuijun Hu, Lan Xu, Shiliang Wu
Pages: 1459-1468
Published online on: 08 April 2014

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Article Open Access

Autografting of bone marrow mesenchymal stem cells alleviates streptozotocin‑induced diabetes in miniature pigs: Real‑time tracing with MRI in vivo

Kuanxiao Tang, Xiaoyan Xiao, Dayue Liu, Yunfeng Shen, Yingming Chen, Yu Wang, Baoying Li, Fei Yu, Dedong Ma, Jinhua Yan, Hua Liang, Daizhi Yang, Jianping Weng
Pages: 1469-1476
Published online on: 07 April 2014

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Article Open Access

Reduced hTERT protein levels are associated with DNA aneuploidy in the colonic mucosa of patients suffering from longstanding ulcerative colitis

Mariann Friis-Ottessen, Paula M. De Angelis, Aasa R. Schjølberg, Solveig N. Andersen, Ole Petter F. Clausen
Pages: 1477-1483
Published online on: 20 March 2014

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Article Open Access

CTC1 increases the radioresistance of human melanoma cells by inhibiting telomere shortening and apoptosis

Y. M. Luo, N. X. Xia, L. Yang, Z. Li, H. Yang, H. J. Yu, Y.  Liu, H. Lei, F. X. Zhou, C. H. Xie, Y. F. Zhou
Pages: 1484-1490
Published online on: 02 April 2014

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Article Open Access

The combination of rapamycin and MAPK inhibitors enhances the growth inhibitory effect on Nara-H cells

Osamu Nakamura, Toshiaki Hitora, Yoshiki Yamagami, Masaki Mori, Hideki Nishimura, Ryosuke Horie, Konosuke Yamaguchi, Tetsuji Yamamoto
Pages: 1491-1497
Published online on: 27 March 2014

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Article Open Access

Nature and mechanisms of hepatocyte apoptosis induced by D-galactosamine/lipopolysaccharide challenge in mice

Yi-Hang Wu, Shao-Qing Hu, Jun Liu, Hong-Cui Cao, Wei Xu, Yong-Jun Li, Lan-Juan Li
Pages: 1498-1506
Published online on: 07 April 2014

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Article

Differentiation of human amniotic fluid-derived mesenchymal stem cells into type II alveolar epithelial cells in vitro

Yaqing Li, Wulin Xu, Jianping Yan, Yingjie Xia, Chao Gu, Yingyu Ma, Houquan Tao
Pages: 1507-1513
Published online on: 19 March 2014

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Article

Increased FoxM1 expression is a target for metformin in the suppression of EMT in prostate cancer

Yiru Wang, Binwei Yao, Yu Wang, Mingbo Zhang, Shuai Fu, Hanjing Gao, Ruiyun Peng, Lingqiang Zhang, Jie Tang
Pages: 1514-1522
Published online on: 20 March 2014

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Article

Suppression of retinal neovascularization by small interfering RNA targeting PGC-1α

Lixin Zhang, Jian Jiang, Xiaobo Xia
Pages: 1523-1530
Published online on: 31 March 2014

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Article

Overexpression of Her-2 upregulates FoxM1 in gastric cancer

Weiwei Qi, Xiaoxiao Li, Yongchun Zhang, Ruyong Yao, Wensheng Qiu, Dongfang Tang, Jun Liang
Pages: 1531-1538
Published online on: 07 April 2014

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Article

Ubiquitin-fold modifier 1 inhibits apoptosis by suppressing the endoplasmic reticulum stress response in Raw264.7 cells

Xiaolei Hu, Qi Pang, Qiongna Shen, Huifang Liu, Jiangping He, Jing Wang, Jie Xiong, Huijie Zhang, Fengling Chen
Pages: 1539-1546
Published online on: 07 April 2014

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Article

Electroacupuncture promotes neural cell proliferation in vivo through activation of the ERK1/2 signaling pathway

Jia Huang, Xiaoqian Ye, Yongmei You, Weilin Liu, Yanling Gao, Shanli Yang, Jun Peng, Zhenfeng Hong, Jing Tao, Lidian Chen
Pages: 1547-1553
Published online on: 18 March 2014

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Article

Expression analysis of serum microRNAs in idiopathic pulmonary fibrosis

Ping Li, Juan Li, Tengfei Chen, Huaqi Wang, Heying Chu, Jingxia Chang, Wenqiao Zang, Yuanyuan Wang, Yunyun Ma, Yuwen Du, Guoqiang Zhao, Guojun Zhang
Pages: 1554-1562
Published online on: 24 March 2014

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Article

Delivery of EZH2-shRNA with mPEG-PEI nanoparticles for the treatment of prostate cancer in vitro

Yinxia Wu, Junjie Yu, Yongbiao Liu, Lin Yuan, Hang Yan, Jing Jing, Guoping Xu
Pages: 1563-1569
Published online on: 04 April 2014

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Article

Premature and severe cardiovascular disease in a Mexican male with markedly low high-density-lipoprotein-cholesterol levels and a mutation in the lecithin:cholesterol acyltransferase gene: A family study

Rosalinda Posadas-Sánchez, Carlos Posadas-Romero, Wendy Angélica Ocampo-Arcos, María Teresa Villarreal-Molina, Gilberto Vargas-Alarcón, Erika Antúnez-Argüelles, Enrique Mendoza-Pérez, Guillermo Cardoso-Saldaña, Rocío Martínez-Alvarado, Aída Medina-Urrutia, Esteban Jorge-Galarza
Pages: 1570-1576
Published online on: 07 April 2014

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Article

Downregulation of p16ink4a inhibits cell proliferation and induces G1 cell cycle arrest in cervical cancer cells

Chu-Yue Zhang, Wei Bao, Li-Hua Wang
Pages: 1577-1585
Published online on: 07 April 2014

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Article

Proteomic and bioinformatic analysis of differentially expressed proteins in denervated skeletal muscle

Hualin Sun, Jiaying Qiu, Yanfei Chen, Miaomei Yu, Fei Ding, Xiaosong Gu
Pages: 1586-1596
Published online on: 08 April 2014

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Article

Differentiation and molecular profiling of human embryonic stem cell-derived corneal epithelial cells

J. Brzeszczynska, K. Samuel, S. Greenhough, K. Ramaesh, B. Dhillon, D. C. Hay, J. A. Ross
Pages: 1597-1606
Published online on: 27 March 2014

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Article

Effects of CCN3 on fibroblast proliferation, apoptosis and extracellular matrix production

Zhanping Ren, Yuxia Hou, Siwei Ma, Yongwei Tao, Jinfeng Li, Huiqin Cao, Lingling Ji
Pages: 1607-1612
Published online on: 08 April 2014

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Article

Aloperine induces G2/M phase cell cycle arrest and apoptosis in HCT116 human colon cancer cells

Li Zhang, Yanxin Zheng, Hongzhu Deng, Lei Liang, Juan Peng
Pages: 1613-1620
Published online on: 31 March 2014

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Article

Deletion of p18INK4c aggravates cisplatin‑induced acute kidney injury

Liang Wang, Wei Chen, Yi Zhang, Chunyan Liu, Li Yuan, Lili Fu, Changlin Mei
Pages: 1621-1626
Published online on: 04 April 2014

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Article

Icariin and icaritin stimulate the proliferation of SKBr3 cells through the GPER1-mediated modulation of the EGFR-MAPK signaling pathway

Hai-Rong Ma, Jie Wang, Yiu-Fai Chen, Hua Chen, Wei-Shan Wang, Haji Akber Aisa
Pages: 1627-1634
Published online on: 03 April 2014

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Article

Semaphorin 3A-Plexin-A1 signaling through ERK activation is crucial for Toll-like receptor-induced NO production in BV-2 microglial cells

Takuji Ito, Tokiko Morita, Kenji Yoshida, Takayuki Negishi, Kazunori Yukawa
Pages: 1635-1642
Published online on: 04 April 2014

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Article

Suppression of allergic and inflammatory responses by essential oils derived from herbal plants and citrus fruits

Mai Mitoshi, Isoko Kuriyama, Hiroto Nakayama, Hironari Miyazato, Keiichiro Sugimoto, Yuko Kobayashi, Tomoko Jippo, Kouji Kuramochi, Hiromi Yoshida, Yoshiyuki Mizushina
Pages: 1643-1651
Published online on: 31 March 2014

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Article

Mutational diversity of NS5A and NS3 during triple therapy (telaprevir, pegylated-interferon-α 2b and ribavirin) for genotype 1b chronic hepatitis C: The Kobe Hepatitis Therapeutic Group

Fugui Bai, Yoshihiko Yano, Soo-Ryang Kim, Yasushi Seo, Akira Miki, Masaya Saito, Hirotaka Hirano, Kenji Momose, Akihiro Minami, Yuri Hatazawa, Takanobu Hayakumo, Dewiyani Indah Widasari, Hanggoro Tri Rinonce, Masahiko Sugano, Satoshi Tani, Seitetsu Yoon, Susumu Imoto, Takeshi Azuma, Hak Hotta, Yoshitake Hayashi
Pages: 1652-1656
Published online on: 19 March 2014

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Article

Quercetin induces apoptosis by inhibiting MAPKs and TRPM7 channels in AGS cells

Min Chul Kim, Hee Jung Lee, Bora Lim, Ki-Tae Ha, Sung Young Kim, Insuk So, Byung Joo Kim
Pages: 1657-1663
Published online on: 18 March 2014

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Article

ERK1/2 pathway mediates epithelial-mesenchymal transition by cross-interacting with TGFβ/Smad and Jagged/Notch signaling pathways in lens epithelial cells

Xiaoyun Chen, Shaobi Ye, Wei Xiao, Wencong Wang, Lixia Luo, Yizhi Liu
Pages: 1664-1670
Published online on: 04 April 2014

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Article

Swimming improves high-fat induced insulin resistance by regulating lipid and energy metabolism and the insulin pathway in rats

An Song, Chao Wang, Luping Ren, Jiajun Zhao
Pages: 1671-1679
Published online on: 09 April 2014

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Journal Cover
January-2026 Volume 57 Issue 1

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

FK506‑binding proteins as emerging bridges linking proteostasis to multi‑system pathogenesis and therapeutic strategies (Review)

Zhi Li, Xiaolei Liu, Hesong Zeng
Article Number: 30
Published online on: 24 November 2025

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Retraction Open Access

[Retracted] Suppression of SIK1 by miR‑141 in human ovarian cancer cell lines and tissues

Jin-Long Chen, Fang Chen, Ting-Ting Zhang, Nai-Fu Liu
Article Number: 29
Published online on: 24 November 2025

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Article Open Access

METTL3 inhibits LINC00312 to suppress osteoporosis progression in a YTHDF2‑dependent manner

Yang Wang, Yihao Tian, Gang Yao
Article Number: 28
Published online on: 20 November 2025

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Review Open Access

Decoding structural birth defects through genomic landscapes: Innovative frameworks for diagnosis (Review)

Ruihao Xu, Haoming Ren, Zhengwei Yuan, Wanqi Huang, Hui Gu
Article Number: 27
Published online on: 20 November 2025

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MOTS‑c protects against placental injury via Nrf2 activation in hypoxia‑induced intrauterine growth restriction mice

Dan Chen, Hui-Min Zhao, Xiao-Lin Sun, Zhi-Xuan Xing, Sheng-Peng Li, Shuai-Chao Li, Ya-Xian Wu, Qing-Feng Pang, Jian-Feng Huang
Article Number: 26
Published online on: 18 November 2025

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Article Open Access

Synergistic effects of Akebia saponin D and Semaglutide on diabetic nephropathy and osteoporosis via the Klotho‑p53 signaling axis

Qian Zhang, Dan Wang, Hongxia Jia, Zongji Zheng, Liyan Lin, Linna Li, Ling Wang, Yaoming Xue
Article Number: 25
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑103 modulates tumor progression by targeting KLF7 in non‑small cell lung cancer

Ke Li, Conghu Yuan
Article Number: 24
Published online on: 17 November 2025

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Article

Comparative analysis of pan MHC‑I epitopes immunoreactivity on Hantaan virus nucleocapsid protein

Zhikui Li, Weijie Ding, Yubo Sun, Chenfeng Tian, Shuaishuai Fu, Fei Shi, Zhenchi Fang, Yuanzhe Li, Jianchang Li, Sirui Cai, Haobo Kang, Baozeng Sun, Junqi Zhang, Yuanjie Sun, Shuya Yang, Yusi Zhang, Chunmei Zhang, Yun Zhang, Xiyang Zhang, Kun Yang, Dongbo Jiang
Article Number: 23
Published online on: 14 November 2025

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Article Open Access

Human papillomavirus E7 inhibits immune responses in keratinocytes by activating HTRA1‑mediated mitophagy

Boya Zhang, Defeng Kong, Siji Chen, Xuewu Sun, Hao Cheng
Article Number: 22
Published online on: 14 November 2025

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Article Open Access

Targeting p38 MAPK signaling pathway: 
Quercetin as a novel therapy for TMJ synovitis

Mosha Cheng, Yuhe Guan, Xiaotao Xin, Xin Yi, Yi Liu
Article Number: 21
Published online on: 13 November 2025

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Review Open Access

Lipid droplets in astrocytes: Key organelles for CNS homeostasis and disease (Review)

Yuchen Wang, Boxuan Wang, Jinchao Hou, Xiaodong Huo, Chenlin Liu, Ruili Guan, Honggang Chen, Yang Zhou, Jianbin Zhang, Congcong Zhuang, Yuankang Zou
Article Number: 20
Published online on: 13 November 2025

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Review Open Access

Copper dyshomeostasis and cardiovascular disease: Molecular mechanisms and new strategies for targeted intervention with cuproptosis (Review)

Peiyu Li, Yinghui Li, Qian Meng, Jie Wang, Kun Wang, Sumin Yang
Article Number: 19
Published online on: 13 November 2025

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Elevated FTO alleviates sepsis‑induced acute kidney injury by regulating macrophage inflammatory phenotypes

Xiaona Chen, Ziqi Sun, Jiabo Chen, Jinquan Zhang, Zeyu Liu, Zhengzheng Yan, Quan Li, Zhixia Chen
Article Number: 18
Published online on: 12 November 2025

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Correction Open Access

[Corrigendum]  Suppression of PAX6 promotes cell proliferation and inhibits apoptosis in human retinoblastoma cells

Bo Meng, Yisong Wang, Bin Li
Article Number: 17
Published online on: 10 November 2025

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Review Open Access

Microbial short chain fatty acids: Effective histone deacetylase inhibitors in immune regulation (Review)

Jing Wang, Qin Zhao, Shuwan Zhang, Jia Liu, Xingyue Fan, Bin Han, Yaqin Hou, Xiaopeng Ai
Article Number: 16
Published online on: 05 November 2025

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Review Open Access

High‑fat diet and cognitive dysfunction: Mechanistic insights into diet‑induced neurodegeneration (Review)

Min You, Fan Wu, Feng Xiong, Xue-Fei Hu, Huan Wu, Li Zhou, Hong-Xing Zhang
Article Number: 15
Published online on: 05 November 2025

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Article Open Access

ROCK inhibition promotes axon and myelin regeneration via PI3K/Akt/GSK3β in a mouse sciatic nerve injury model

Shuang Dou, Zhijun Li, Boyao Zheng, Zhenyu Ren, Hai Wang, Qing Zuo, Fang Fang, Yuehong Zhuang
Article Number: 14
Published online on: 05 November 2025

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Review Open Access

Mechanisms of mTORC1 and GCN2 amino acid sensing pathways in tumorigenesis and metastatic progression (Review)

Chaowei Zhang, Yuxuan Han, Weiyi Yao, Qing Hong, Na Chen
Article Number: 13
Published online on: 04 November 2025

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β‑hydroxybutyric acid as a potential therapeutic metabolite for type 2 diabetes mellitus (Review)

Xianyi Ding, Jiabin Wu, Lian Wang, Ke Li, Haoyang Gao, Mingyu Wu, Qiuyu Zhang, Ruonan Han, Wenhong Wang, Weihua Xiao
Article Number: 12
Published online on: 03 November 2025

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Review

Histone lactylation: Unveiling a novel pathway for the impact of lactate on physiological and pathological processes (Review)

Xunjie Jian, Chang Cheng, Wenjie Lu, Hui Peng, Diqi Yang
Article Number: 11
Published online on: 03 November 2025

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Review Open Access

Interpretation of the molecular mechanism and therapeutic potential of microRNA‑155 in cardiovascular and cerebrovascular diseases (Review)

Xitong Zhao, Pengqin Wang
Article Number: 10
Published online on: 03 November 2025

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Expression of Concern Open Access

[Expression of Concern]  CDKN2A (p16INK4A) affects the anti‑tumor effect of CDK inhibitor in somatotroph adenomas

Yiyuan Chen, Zhenye Li, Qiuyue Fang, Hongyun Wang, Chuzhong Li, Hua Gao, Yazhuo Zhang
Article Number: 9
Published online on: 29 October 2025

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Article Open Access

TWEAK modulates the characteristics of periodontal ligament stem cells via the Fn14/NF‑κB pathway

Linlin Xiao, Man Qu, Lulu Chen, Mingli Xiang, Qian Long, Jianguo Liu, Xiaoyan Guan, Chengcheng Liao
Article Number: 8
Published online on: 27 October 2025

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Review Open Access

Harnessing copper: Innovative approaches to combat neurodegenerative diseases and cancer (Review)

Tao Duan, Hanhai Mao, Xingyue Jiang, Ying Tian, Jidong Zhang, Jun Tan
Article Number: 7
Published online on: 27 October 2025

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Retraction Open Access

[Retracted] Effects of miR‑106b‑3p on cell proliferation and epithelial‑mesenchymal transition, and targeting of ZNRF3 in esophageal squamous cell carcinoma

Guanen Qiao, Chenguang Dai, Yang He, Junjie Shi, Chunfang Xu
Article Number: 6
Published online on: 27 October 2025

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Review Open Access

Immune and metabolic remodeling following bariatric surgery: Implications for targeted immunotherapy (Review)

Yiming Shao, Ke Song, Ruixin Yu, He Xiao, Chengjun Li, Yuling Deng, Yuan Zhang, Yixing Ren
Article Number: 5
Published online on: 24 October 2025

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Article Open Access

Exportin 1 inhibitor KPT‑330 reverses oxaliplatin resistance via p53 nuclear retention in colorectal cancer

Chuanxi Lai, Xiya Jia, Yiyi Chen, Kangke Chen, Fei Wang, Qiqi Zhang, Xiaonan Xiang, Zhe-Sheng Chen, Lingna Xu, Sheng Dai
Article Number: 4
Published online on: 23 October 2025

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Article Open Access

Targeting of CIRP attenuates osteoarthritis progression via suppressing TLR4/NF‑κB/NLRP3 signaling axis

Weichao Sun, Yi Liao, Jianguo Feng, Jianhui Liang, Qifei He, Yinxing Cui, Dixi Huang, Houyin Shi, Wei You, Wei Sun, Qian Yi
Article Number: 3
Published online on: 23 October 2025

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Review

Importance of B cells (Review)

Zhiyuan Liu, Haoran Dai, Xiaoyu Cui, Yeping Liu, Zhaocheng Dong
Article Number: 2
Published online on: 22 October 2025

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Retraction Open Access

[Retracted] Hypoxic preconditioned bone mesenchymal stem cells ameliorate spinal cord injury in rats via improved survival and migration

Weiheng Wang, Xiaodong Huang, Wenbo Lin, Yuanyuan Qiu, Yunfei He, Jiangming Yu, Yanhai Xi, Xiaojian Ye
Article Number: 1
Published online on: 22 October 2025

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Journal Cover
February-2026 Volume 57 Issue 2

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

STOML2 interacts with PHB to activate the MEK/ERK signaling pathway and mediates autophagy‑related proteins in the progression of hepatocellular carcinoma

Haoyang Hu, Haozhe Zhang, Shuai Han, Jianli Chen, Ying Xie
Article Number: 38
Published online on: 04 December 2025

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HMGB1 mediates low-dose ionizing radiation-induced Wnt/β-catenin activation in SRA01/04 cells: Mechanistic clues to early cataractogenesis

Ping Wang, Chunnan Piao, Dong Yan, Yingxue He, Yaru Li, Li Fan, Mei Tian
Article Number: 37
Published online on: 04 December 2025

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Article Open Access

FBXO22 promotes hepatocellular carcinoma progression via paracrine myo‑inositol‑induced M2‑type polarization of macrophages

Liangliang Bai, Jing Xiong, Sihai Chen, Jiahao Hu, Meixia Zhang, Bimin Li, Jing Hu, Mingyan He
Article Number: 36
Published online on: 02 December 2025

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Review Open Access

Branched‑chain amino acid metabolism and bone metabolism: Implications for osteoporosis pathogenesis and therapeutic strategies (Review)

Qi Xiao, Haimin Zeng, Ruhui Yang, Yuxin Zhan, Fangzhen Lin, Bofan Chen, Xiang Chen
Article Number: 35
Published online on: 02 December 2025

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Review Open Access

Mitochondria-associated endoplasmic reticulum membranes: Emerging regulators of cardiac microvascular ischemia/reperfusion injury (Review)

Yan Wang, Baowei Feng, Yanting Wu, Zongle Sun, Hao Yuan, Wei Chen, Chang Zhao, Zhi Liu
Article Number: 34
Published online on: 02 December 2025

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Review Open Access

Role of matrix metalloproteinases in the invasion of glioblastoma and drug interventions (Review)

Bohao Zheng, Ying Han, Haiying Zhang
Article Number: 33
Published online on: 01 December 2025

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Review

Bridging bench to bedside: Exosome‑based strategies for endometriosis diagnosis and treatment (Review)

Wanmeng Chen, Yujiu Ma, Xudong Zhang, Siwen Zhang, Shanshan Wu, Yimeng Lu, Jichun Tan
Article Number: 32
Published online on: 01 December 2025

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Retraction Open Access

[Retracted] miR‑381 functions as a tumor suppressor by targeting ETS1 in pancreatic cancer

Guanen Qiao, Jing Li, Jun Wang, Zhaoyang Wang, Wei Bian
Article Number: 31
Published online on: 01 December 2025

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