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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
November-December 2011 Volume 2 Issue 6

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Review

The role of miR-26 in tumors and normal tissues (Review)

Jie Gao, Qing-Guang Liu
Pages: 1019-1023
Published online on: 05 September 2011

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Article Open Access

Fascin expression in dendritic cells and tumor epithelium in thymoma and thymic carcinoma

Junichiro Sato, Masachika Fujiwara, Tomohiro Kawakami, Ayumi Sumiishi, Seiji Sakata, Atsuhiko Sakamoto, Atsushi Kurata
Pages: 1025-1032
Published online on: 17 August 2011

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Article Open Access

Pharmacokinetic and pharmacodynamic profiles of subcutaneous administration of continuous erythropoietin receptor activator in lung cancer patients with anemia induced by chemotherapy

Toshiaki Takahashi, Nobuyuki Yamamoto, Tomohide Tamura, Hideo Kunitoh, Yutaka Nishiwaki, Shunichi Negoro
Pages: 1033-1040
Published online on: 29 August 2011

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Article

Expression of hepatocyte markers in mass-forming peripheral and periductal-infiltrating hilar intrahepatic cholangiocarcinomas

Hiroya Iida, Masaki Hata, Ayako Kakuno, Hiroshi Hirano, Koji Yamanegi, Naoko Yamada, Hideki Ohyama, Nobuyuki Terada, Chiaki Yasui, Naoki Yamanaka, Keiji Nakasho
Pages: 1041-1046
Published online on: 02 September 2011

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Article

Matrix metalloproteinase 3 is a stromal marker for chicken ovarian cancer

Jin Won Choi, Suzie E. Ahn, Deivendran Rengaraj, Hee Won Seo, Whasun Lim, Gwonhwa Song, Jae Yong Han
Pages: 1047-1051
Published online on: 19 August 2011

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Article

Programmed cell death 4 (Pdcd4) expression in colorectal adenocarcinoma: Association with clinical stage

Sung-Chul Lim, Ran Hong
Pages: 1053-1057
Published online on: 22 July 2011

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Article

Differential efficacy of docetaxel according to non‑small cell lung cancer histology and the therapeutic effect of epidermal growth factor receptor tyrosine kinase inhibitors

Satoru Miura, Haruyasu Murakami, Akihiro Tamiya, Sakae Morii, Hiroaki Akamatsu, Akira Ono, Takehito Shukuya, Hirotsugu Kenmotsu, Asuka Tsuya, Yukiko Nakamura, Kyoichi Kaira, Tateaki Naito, Toshiaki Takahashi, Masahiro Endo, Takashi Nakajima, Nobuyuki Yamamoto
Pages: 1059-1064
Published online on: 31 August 2011

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Article

CD133, OCT4, and NANOG in ulcerative colitis-associated colorectal cancer

Hiromi Yasuda, Koji Tanaka, Yoshiki Okita, Toshimitsu Araki, Susumu Saigusa, Yuji Toiyama, Takeshi Yokoe, Shigeyuki Yoshiyama, Aya Kawamoto, Yasuhiro Inoue, Chikao Miki, Masato Kusunoki
Pages: 1065-1071
Published online on: 06 September 2011

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Article

Gastric cavernous hemangioma: A rare case with upper gastrointestinal bleeding

Liang Zong, Ping Chen, Guo Hao Shi, Lei Wang
Pages: 1073-1075
Published online on: 21 July 2011

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Article

Trisomy chromosome 5 is a recurrent cytogenetic lesion in mammary tumors from parous MMTV-erbB-2 transgenic mice

Young Mi Kim, Zhikun Ma, Seungjik Lee, Jiyun Lee, Shibo Li, Xiaohe Yang
Pages: 1077-1081
Published online on: 04 August 2011

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Article

Fusion between cancer cells and myofibroblasts is involved in osteosarcoma

Ling Yu, Weichun Guo, Shenghao Zhao, Fuan Wang, Yong Xu
Pages: 1083-1087
Published online on: 14 July 2011

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Article

Evidence for PTEN-independent Akt activation and Akt-independent p27Kip1 expression in advanced bladder cancer

J. Mundhenk, J. Hennenlotter, L. Zug, S.h. Alloussi, T. Todenhoefer, G. Gakis, S. Aufderklamm, M. Scharpf, U. Kuehs, A. Stenzl, C. Schwentner
Pages: 1089-1093
Published online on: 05 August 2011

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Article

High-level expression of stem cell marker CD133 in clear cell renal cell carcinoma with favorable prognosis

Kyungeun Kim, Hyojin Ihm, Jae Y. Ro, Yong Mee Cho
Pages: 1095-1100
Published online on: 02 August 2011

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Article

Elevated microRNA-126 is associated with high vascular endothelial growth factor receptor 2 expression levels and high microvessel density in colorectal cancer

Torben Frøstrup Hansen, Claus Lindbjerg Andersen, Boye Schnack Nielsen, Karen-Lise Garm Spindler, Flemming Brandt Sørensen, Jan Lindebjerg, Ivan Brandslund, Anders Jakobsen
Pages: 1101-1106
Published online on: 04 August 2011

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Case Report

Primary retroperitoneal malignant melanoma: A case report

Guo-Bing Liu, Guang-Yao Wu, Prasanna Ghimire, Zai-Peng Zhang
Pages: 1107-1111
Published online on: 29 August 2011

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Article

Acquisition of selective antitumoral effects of recombinant adeno-associated virus by genetically inserting tumor-targeting peptides into capsid proteins

Han Saem Lee, Ji Yun Kim, Won Il Lee, Sung Jin Kim, Min Ji Ko, Sunjoo Jeong, Keerang Park, Han Choe, Heuiran Lee
Pages: 1113-1119
Published online on: 08 August 2011

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Article

RNAi targeting of hTERT gene expression induces apoptosis and inhibits the proliferation of lung cancer cells

Linhu Ge, Wenlong Shao, Yangde Zhang, Yuan Qiu, Dong  Cui, Donghai Huang, Zhansheng Deng
Pages: 1121-1129
Published online on: 19 August 2011

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Article

Update on the molecular profile of the MDA-MB-453 cell line as a model for apocrine breast carcinoma studies

Semir Vranic, Zoran Gatalica, Zhao-Yi Wang
Pages: 1131-1137
Published online on: 05 August 2011

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Article

Elevated expression of solute carrier family 22 member 18 increases the sensitivity of U251 glioma cells to BCNU

Sheng-Hua Chu, Yan-Bin Ma, Dong-Fu Feng, Hong Zhang, Jian-Hua Qiu, Zhi-An Zhu
Pages: 1139-1142
Published online on: 04 August 2011

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Article

Vascular endothelial growth factor-A and changes in a tumor-bearing mouse model with Lewis lung cancer

Meng-shu Tsai, Cheng-chi Chang, Min-liang Kuo, Ying-tai  Wu
Pages: 1143-1147
Published online on: 09 August 2011

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Article

Expression of GLUT1 is associated with increasing grade of malignancy in non-invasive and invasive urothelial carcinomas of the bladder

Henning Reis, Stephan Tschirdewahn, Tibor Szarvas, Herbert Rübben, Kurt Werner Schmid, Florian Grabellus
Pages: 1149-1153
Published online on: 29 August 2011

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Article

IGF-IR in patients with advanced colorectal cancer in correlation with certain clinico-morphological factors: Initial report

Adam Kuklinski, Zbigniew Kamocki, Mariusz Koda, Zdzislaw Piotrowski, Stanislaw Sulkowski, Ryszard Lesniewicz, Krystyna Pawlak, Piotr Mysliwiec, Boguslaw Kedra
Pages: 1155-1159
Published online on: 29 August 2011

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Article

Effect of magnetic fluid hyperthermia on lung cancer nodules in a murine model

Runlei Hu, Shenglin Ma, Hu Li, Xianfu Ke, Guoqing Wang, Dongshan Wei, Wei Wang
Pages: 1161-1164
Published online on: 09 August 2011

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Article

Effect of temozolomide on the U-118 glioma cell line

A. Carmo, H. Carvalheiro, I. Crespo, I. Nunes, M. C. Lopes
Pages: 1165-1170
Published online on: 02 September 2011

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Article

Expression of VEGF and MMP-9 and MRI imaging changes in cerebral glioma

Yang Liu, Yang Zhou, Xiu-Shi Zhang, Bao-Zhong Shen
Pages: 1171-1175
Published online on: 17 August 2011

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Article

Overexpression of 14-3-3σ counteracts tumorigenicity by positively regulating p73 in vivo

Cuizhi Geng, Meixiang Sang, Ruiling Yang, Wei Gao, Tao Zhou, Shijie Wang
Pages: 1177-1182
Published online on: 31 August 2011

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Article

The prognostic importance of cathepsin D and E-cadherin in early breast cancer: A single-institution experience

Galia Jacobson-Raber, Irena Lazarev, Victor Novack, Willmosh Mermershtein, Yael Baumfeld, David B. Geffen, Netta Sion-Vardy, Samuel Ariad
Pages: 1183-1190
Published online on: 24 August 2011

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Article

The prolyl isomerase Pin1 is overexpressed in human esophageal cancer

Huawei Jin, Jie Jiang, Lifang Sun, Fangfang Zheng, Chengyan Wu, Lin Peng, Yufen Zhao, Xueji Wu
Pages: 1191-1196
Published online on: 23 August 2011

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Article

Expression of stromal cell-derived factor-1α is an independent risk factor for lymph node metastasis in early gastric cancer

Ik-Chan Song, Zhe-Long Liang, Jung-Chan Lee, Song-Mei Huang, Ha-Yon Kim, Yoon-Suk Oh, Hwan-Jung Yun, Ji-Young Sul, Deog-Yeon Jo, Samyong Kim, Jin-Man Kim, Hyo-Jin Lee
Pages: 1197-1202
Published online on: 19 August 2011

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Article

Impaired nuclear export of tumor-derived c-terminal truncated cyclin D1 mutant in ESCC cancer

Meili Hao, Xiangmei Chen, Ting Zhang, Tao Shen, Qing Xie, Xiujuan Xing, Hongxi Gu, Fengmin Lu
Pages: 1203-1211
Published online on: 02 September 2011

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Article

Effects of TRPM8 on the proliferation and angiogenesis of prostate cancer PC-3 cells in vivo

Guangbin Zhu, Xinghuan Wang, Zhonghua Yang, Hong  Cao, Zhe Meng, Yongzhi Wang, Dong Chen
Pages: 1213-1217
Published online on: 02 September 2011

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Article

Expression of PPARγ and PTEN in human colorectal cancer: An immunohistochemical study using tissue microarray methodology

Mao Song Lin, Jun Xing Huang, Wei Chang Chen, Bao Feng Zhang, Jing Fang, Qiong Zhou, Ying Hu, Heng Jun Gao
Pages: 1219-1224
Published online on: 06 September 2011

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Article

Role of inflammation in oral carcinogenesis (Part I): Histological grading of malignancy using a binary system

Marta Rabello Piva, Lélia Batista De Souza, Paulo Ricardo Saquete Martins-Filho, Rosilene Calazans Soares, Thiago De Santana Santos, Emanuel Sávio De Souza Andrade
Pages: 1225-1231
Published online on: 16 August 2011

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Article

Mutations of the epidermal growth factor receptor gene in NSCLC patients

Bing Han, Xiang Zhou, Rong-Xin Zhang, Wang-Fu Zang, Zhong-Yuan Chen, Huai-Dong Song, Huan-Ying Wan, Cui-Xia Zheng
Pages: 1233-1237
Published online on: 25 July 2011

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Case Report

Long-term efficacy of oral alendronate therapy in an elderly patient with polyostotic fibrous dysplasia: A case report

Gui-dong Li, Akira Ogose, Tetsuo Hotta, Hiroyuki  Kawashima, Takashi  Ariizumi, Yongjun Xu, Naoto Endo
Pages: 1239-1242
Published online on: 02 August 2011

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Article

Consumption of vitamin B6 reduces colonic damage and protein expression of HSP70 and HO-1, the anti-tumor targets, in rats exposed to 1,2-dimethylhydrazine

Tomoko Kayashima, Kenta Tanaka, Yukako Okazaki, Kiminori Matsubara, Noriyuki Yanaka, Norihisa Kato
Pages: 1243-1246
Published online on: 02 August 2011

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Article

A possible predictive marker of progression for hepatocellular carcinoma

Michele Di Stasio, Maria Grazia Volpe, Giovanni Colonna, Melissa Nazzaro, Miriam Polimeno, Stefania Scala, Giuseppe Castello, Susan Costantini
Pages: 1247-1251
Published online on: 09 August 2011

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Article

A phase II study of mitomycin-C and S-1 as third-line chemotherapy in patients with advanced colorectal cancer

Jung Han Kim, Hyeong Su Kim, Dae Ro Choi, Geundoo Jang, Jung Hye Kwon, Ho Young Kim, Joo Young Jung, Hyo Jung Kim, Hun Ho Song, Yun Ho Shin, So Young Jung, Byung Chun Kim, Dae Young Zang
Pages: 1253-1256
Published online on: 27 July 2011

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Article

hTERT methylation is necessary but not sufficient for telomerase activity in colorectal cells

Cristina Valls-Bautista, Stéphanie Bougel, Carme  Piñol‑Felis, Joan Viñas-Salas, Jean Benhattar
Pages: 1257-1260
Published online on: 18 August 2011

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Article

Correlation of macrophage migration inhibitory factor gene polymorphism with the risk of early stage cervical cancer and lymphatic metastasis

Suhui Wu, Junfang Lian, Huijuan Tao, Haixia Shang, Li Zhang
Pages: 1261-1267
Published online on: 02 September 2011

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Article

Comparative expression of matrix metalloproteinases in low‑grade mucoepidermoid carcinoma and typical lung cancer

Jiang Fan, Feng-Ying Wu, Lei Wang, Ge-Ning Jiang, Wen Gao
Pages: 1269-1273
Published online on: 18 August 2011

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Article

Runx3 expression in lymph nodes with metastasis is associated with the outcome of gastric cancer patients

Hong-Wei Xu, Feng Ren, Yan-Ming Yu, Cheng-Zhong Cai
Pages: 1275-1279
Published online on: 11 August 2011

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Article

Estradiol induces JNK-dependent apoptosis in glioblastoma cells

Nedret Altiok, Melike Ersoz, Meral Koyuturk
Pages: 1281-1285
Published online on: 17 August 2011

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Article

Novel BRCA1 deleterious mutation (c.1949_1950delTA) in a woman of Senegalese descent with triple-negative early-onset breast cancer

Orland Diez, Amadeu Pelegrí, Neus Gadea, Sara Gutiérrez-Enríquez, Miriam Masas, Anna Tenés, Nina Bosch, Judith Balmaña, Begoña Graña
Pages: 1287-1289
Published online on: 19 August 2011

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Article

HSulf-1 suppresses cell growth and down-regulates Hedgehog signaling in human gastric cancer cells

Hui-Yan Ma, Fang Zhang, Jie Li, Min-Li Mo, Zhao Chen, Lili Liu, Hai-Meng Zhou, Qing Sheng
Pages: 1291-1295
Published online on: 02 September 2011

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Article

Association of insulin-like growth factor-1 with thyroid nodules

Ying‑Jian Liu, Wei Qiang, Xing‑Jun Liu, Li Xu, Hui Guo, Li‑Ping Wu, Bingyin Shi
Pages: 1297-1301
Published online on: 02 September 2011

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Article

Oridonin-induced apoptosis in SW620 human colorectal adenocarcinoma cells

Zhe Ji, Qingjiu Tang, Jinsong Zhang, Yan Yang, Yanfang Liu, Yingjie Pan
Pages: 1303-1307
Published online on: 02 September 2011

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Article

Emetine regulates the alternative splicing of caspase 9 in tumor cells

Danmin Pan, Kritsanapol Boon-Unge, Piyarat Govitrapong, Jianhua Zhou
Pages: 1309-1312
Published online on: 29 August 2011

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Article

Effects of S-1 as a second-line chemotherapy for patients with relapsed pancreatic cancer

Keinosuke Ishido, Yoshikazu Toyoki, Daisuke Kudo, Norihisa Kimura, Daisuke Yamana, Takuya Miura, Shinji Tsutsumi, Takahiro Muroya, Toru Yoshikawa, Hiroshi Ogasawara, Shinnosuke  Yonaiyama, Shunji Narumi, Kenichi Hakamada
Pages: 1313-1317
Published online on: 05 September 2011

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Article

Expression of MMP-3 and TIMP-3 in gastric cancer tissue and its clinical significance

Hong-Qi Liu, Shu Song, Jian-Hua Wang, Shao-Lan Zhang
Pages: 1319-1322
Published online on: 31 August 2011

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Case Report

The rare case of giant cell tumor occuring in the axial skeleton after 15 years of follow-up: Case report

Ye-Soo Park, Jin Kyu Lee, Seung-Wook Baek, Chan-Kum Park
Pages: 1323-1326
Published online on: 02 September 2011

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Article

Different expression of alternative lengthening of telomere (ALT)-associated proteins/mRNAs in osteosarcoma cell lines

Yi Zhang, Lin Cai, Ren-Xiong Wei, Hao Hu, Wei Jin, Xiao-Bin Zhu
Pages: 1327-1332
Published online on: 02 September 2011

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Journal Cover
January-2026 Volume 31 Issue 1

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Predictive analysis of BRAF V600E mutation and central lymph node metastasis in papillary thyroid carcinoma

Junhui Peng, Zhihui Wu, Yujun Huang, Runhua Pan, Zhongdai Fu, Jianzhang Wang
Article Number: 44
Published online on: 24 November 2025

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Case Report Open Access

Adverse events induced by the subcutaneous HER2-targeted antibody‑drug conjugate JSKN033 in a male patient with breast cancer: A case report

Rui Yang, Jian Zhang, Yang Wang
Article Number: 43
Published online on: 24 November 2025

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Article Open Access

Prediction of solitary ≤3‑cm small adrenal metastasis based on 18F‑FDG PET/CT using a support vector machine model in lung cancer

Lin Zhao, Haifeng Cai, Jingwu Li, Wenzhe Zhao, Yongliang Liu, Lixiu Cao
Article Number: 42
Published online on: 24 November 2025

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Article Open Access

Transferrin receptor serves a role in promoting PANoptosis in thyroid cancer

Shungao Ma, Zhiqiang Ma, Jingwei Shen, Hong Liu, Hua Yang, Yuqin Hu, Simeng Ying
Article Number: 41
Published online on: 24 November 2025

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Review Open Access

Oxidative stress as a nexus: Integrating mitophagy and ferroptosis in endometrial carcinogenesis (Review)

Qixia Yu, Liangxin Ren, Feng Ren, Fengling Li
Article Number: 40
Published online on: 20 November 2025

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Review Open Access

Astragalin: A promising herbal compound with broad anticancer potential (Review)

Yu-Qian Fu, Chan Li, Dan-Ni Ding, Fang-Yuan Liu, Yu-Fei Zhu, Feng-Juan Han
Article Number: 39
Published online on: 20 November 2025

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Article Open Access

Analysis of prognostic factors influencing brain metastasis in EGFR‑mutant lung adenocarcinoma and comparison of prognostic assessment models

Junjun Miao, Jianwei Hu, Yongxia Zhang, Lei Gao, Xiangkun Yuan
Article Number: 38
Published online on: 18 November 2025

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Case Report

Fumarate hydratase-deficient renal cell carcinoma arising in acquired cystic kidney disease in a hemodialysis patient: Diagnostic clues from percutaneous renal mass core needle biopsy: A case report

Yuki Oba, Hisashi Kamido, Kei Kono, Katsuyuki Miki, Shinji Ito, Akinari Sekine, Shigekazu Kurihara, Masayuki Yamanouchi, Tatsuya Suwabe, Yutaka Takazawa, Kenichi Ohashi, Yoji Nagashima, Yuki Nakamura, Yoshifumi Ubara, Naoki Sawa
Article Number: 37
Published online on: 18 November 2025

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Article Open Access

TIMP1 expression in colorectal cancer: Linking prognosis, tumor immunity and molecular pathways

Jiming Gu, Dongming Zhu, Fan Chen, Tongguo Shi, Suhua Xia
Article Number: 36
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] Exosomes from LNCaP cells promote osteoblast activity through miR‑375 transfer

Su-Liang Li, Na An, Bing Liu, Sheng-Yu Wang, Jian-Jun Wang, Yun Ye
Article Number: 35
Published online on: 17 November 2025

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Article

TAS‑102 plus bevacizumab as salvage treatment in colorectal cancer: A retrospective study

Keita Matsumoto, Ryoma Yokoi, Chika Mizutani, Ryuichi Asai, Jesse Yu Tajima, Masahide Endo, Yuji Hatanaka, Takeshi Horaguchi, Masahiro Fukada, Itaru Yasufuku, Yuta Sato, Yoshihiro Tanaka, Katsutoshi Murase, Nobuhisa Matsuhashi
Article Number: 34
Published online on: 14 November 2025

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Review Open Access

Research progress on neutrophil extracellular traps and hepatitis‑to‑hepatocellular carcinoma transformation (Review)

Yiwei Wang, Chengyan Zhang, Haonan Wang, Yali Zhou, Yuanbo Yu, Hui Liu, Chuansha Gu
Article Number: 33
Published online on: 14 November 2025

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Case Report Open Access

Remarkable response to Osimertinib plus Gumarontinib for EGFR mutation and concomitant MET exon 14 skipping in a patient with lung adenocarcinoma: A case report

Xuquan Jing, Li Li, Shuangqing Lu, Xiaoyang Zhai, Hui Zhu
Article Number: 32
Published online on: 12 November 2025

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Article Open Access

Machine learning‑based signature for prognosis and drug sensitivity in hepatocellular carcinoma using glycolysis‑related gene

Yufan Zhou, Wei Liu, Zhixue Fang, Ke Zhou, Xing Huang, Shanzheng Lu, Weilin Zhang, Qiaocheng Wen, Xu Chen, Zhigang Xiao
Article Number: 31
Published online on: 12 November 2025

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Case Report Open Access

Dual immune checkpoint inhibitor cardonilumab induces immune myocarditis in a patient with cancer‑related myocardial metastasis: A case report

Tianxing Liu, Qiang Li, Renya Zeng, Baidong Zhang, Zhichao Kang, Pengfei Zhang, Zhe Yang
Article Number: 30
Published online on: 12 November 2025

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Article Open Access

Retrospective analysis of clinical characteristics, treatment outcomes and prognosis of patients with natural killer/T‑cell lymphoma

Pengye Li, Geraldine Esther Awakossa, Lu Zhou, Qiuhui Li, Xinxiu Liu, Fang Zhu, Tao Liu, Liling Zhang
Article Number: 29
Published online on: 11 November 2025

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Review Open Access

From mechanism to targeted therapy: Advances in histone lactylation‑driven cancer progression (Review)

Zhe Jia, Shan Lu, Zhenchuan Wang, Pengfei Ge
Article Number: 28
Published online on: 11 November 2025

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Retraction Open Access

[Retracted] Upregulation of cervical carcinoma expressed PCNA regulatory long non‑coding RNA promotes esophageal squamous cell carcinoma progression

Xiaojun Wang, Liangfen Zhou, Huiyun Zhang, Hui Ou, Wenxing Long, Xiaobao Liu
Article Number: 27
Published online on: 10 November 2025

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Review Open Access

Biology of PEST‑containing nuclear proteins as potential targets in ovarian cancer (Review)

Hao Liu, Zhi-Liang Jiang, Yi Liu, Yong-Hao Zhu, Muhammad Usman Akbar, Saadullah Khattak, Zhendong Lu, Muhammad Babar Khawar, Yue Zhang, Umair Ali Khan Saddozai, Xin-Ying Ji
Article Number: 26
Published online on: 07 November 2025

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Article

Survival outcomes and prognostic factors in temporal bone malignancies: A retrospective cohort of 20 patients

Liming Gao, Wenyang Zhang, Ting Ye, Rui Guo, Yin Xia
Article Number: 25
Published online on: 06 November 2025

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Article Open Access

Real‑world performance of the machine learning‑based prediction of chemotherapy‑associated adverse effects in lung cancer

Sha Huang, Zhengwei Huang, Zhoujian Sun, Tianao Xie, Xingyu Zhu, Sheng Lu, Zhengxing Huang, Jian Hu, Zhengfu He
Article Number: 24
Published online on: 06 November 2025

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Article Open Access

Long non‑coding RNA RP11‑196G11.6 inhibits neuroblastoma progression by regulating the miR‑376a‑3p/RYBP signaling axis

Jie Zhang, Kai Huang, Jianwu Zhou, Wenge Liao, Fei Li, Zhenzhen Zhao, Shan Wang
Article Number: 23
Published online on: 06 November 2025

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Review

Cervical cancer immune microenvironment: Mechanisms of HPV‑mediated immune evasion and advances in immunotherapy (Review)

Xiaojing Zhou, Ren An, Xiangjuan Li
Article Number: 22
Published online on: 05 November 2025

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Review Open Access

Mesenchymal stem cell‑derived exosomes: Regulators of progression and suppression in pancreatic cancer (Review)

Haoyan Zhuang, Xuewen Shi
Article Number: 21
Published online on: 04 November 2025

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Review Open Access

Advancements in research regarding the influence of the tumor microenvironment on the proliferation and metastasis of osteosarcoma (Review)

Tao Shi, Jianping Kang, Qiyang Wang, Jiamei Song, Xiaofeng He
Article Number: 20
Published online on: 04 November 2025

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Article Open Access

Enhanced expression of CXCL1 in renal cell carcinoma facilitates tumor cell malignancy via PI3K/AKT‑dependent mechanisms

Shiliang Gui, Hongrui Zhang, Huiting Xiao, Chen Liu, Yuhang Wang, Baotian Wang, Hongbin Qiu
Article Number: 19
Published online on: 03 November 2025

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Case Report Open Access

Photodynamic therapy with local‑targeted perfusion for recurrent tracheal adenoid cystic carcinoma achieving 12‑year survival: A case report

Luoqi Yang, Lu Wang, Hongwu Wang, Heng Zou
Article Number: 18
Published online on: 03 November 2025

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Retraction Open Access

[Retracted] Tunicamycin inhibits progression of glioma cells through downregulation of the MEG‑3‑regulated wnt/β‑catenin signaling pathway

Xin Li, Lei Xue, Qin Peng
Article Number: 17
Published online on: 03 November 2025

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Article Open Access

Non‑targeted metabolomics reveals diagnostic biomarker in the plasma of patients with lung cancer

Yan Liu, Yangmin Li, Haijun Hou, Yanyan Dong, Haitong Tian, Yanan Zhao, Ke Li, Jiayuan Zhou, Fujie Song, Yan Li
Article Number: 16
Published online on: 31 October 2025

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Article Open Access

Primary pulmonary angiosarcoma: A case study with genetic insights and potential therapeutic targets

Yanling Zhu, Chunfang Guo
Article Number: 15
Published online on: 31 October 2025

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Review Open Access

Progress in the treatment of esophageal neuroendocrine carcinoma (Review)

Jie Shi, Bin He, Heng Di Zhang, Chao Yang Jiang, Ling Zhang
Article Number: 14
Published online on: 31 October 2025

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Article Open Access

Sensitive cell‑free DNA assay for accurate detection of RAS and BRAF mutations in liquid biopsies of patients with metastatic colorectal cancer: Final results of the multicentric ColoBEAM study

Alexandre Harlé, Céline Gavoille, Olivier Bouché, Meher Ben Abdelghani, Jérome Plaza, Dominique Spaeth, Axelle Boudrant, François Ghiringhelli, Anne-Laure Villing, Christophe Borg, Marie Rouyer, Marie Husson, Pauline Gilson, Julia Salleron, Aurélien Lambert, Jean-Louis Merlin
Article Number: 13
Published online on: 30 October 2025

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Article

Single‑center retrospective study of factors associated with early discontinuation of tumor‑treating fields therapy in glioblastoma

Kohei Suzuki, Koichiro Sato, Shohei Nagasaka, Ryo Miyaoka, Takeshi Saito, Yoshiteru Nakano, Nayuta Higa, Toshiaki Akahane, Akihide Tanimoto, Ryosuke Hanaya, Junkoh Yamamoto
Article Number: 12
Published online on: 29 October 2025

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Review Open Access

Clinical value of emerging peripheral blood protein biomarkers in prostate cancer (Review)

Mengli Chen, Feng Wang, Weixi Wang, Kangle Feng, Kaihua Xiang, Xubo Gong, Zhihua Tao, Weiwei Liu
Article Number: 11
Published online on: 29 October 2025

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Article Open Access

Intratumoral and peritumoral radiomics of MRI predict pathological differentiation in patients with rectal cancer

Huanhui Liu, Hanjing Zhang, Qian Zou, Jianquan Yang
Article Number: 10
Published online on: 29 October 2025

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Retraction Open Access

[Retracted] Peritumoral activated hepatic stellate cells are associated with hepatic recurrence for resectable colorectal adenocarcinoma liver metastasis following resection

Li Deng, Taiyuan Li, Yuanyuan Liao, Shuang Liu, Zhen Xie, Zhixiang Huang, Hua Dai, Jianfeng Li, Xiong Lei
Article Number: 9
Published online on: 27 October 2025

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Case Report Open Access

Combined BRAF/MEK inhibition for BRAF‑mutant melanoma brain metastases in pregnancy: A case report

Jaroslav Melus, Michaela Jezberova, Silvia Mikulajova, Katarina Komaromy Gerincova, Martin Karlik, Igor Straka, Marek Krivosik, Peter Valkovic, Gabriela Timarova
Article Number: 8
Published online on: 24 October 2025

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Case Report Open Access

Synchronous rectal and endometrial cancer: A case report and literature review

Zhuofan Li, Li Peng, Qing Su, Beige Zong
Article Number: 7
Published online on: 24 October 2025

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Article

Predictive significance of thoracic skeletal muscle nutritional status for radiotherapy survival in elderly patients with esophageal squamous cell carcinoma

Shuqin Liu, Qi Li, Dongmei Luo, Caixia Jia, Dingqiang Peng, Guihong Liu
Article Number: 6
Published online on: 24 October 2025

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Review Open Access

Ribosome‑binding protein 1: A multidimensional regulator of cancer progression and a novel target for precision therapy (Review)

Ho Huang, Jia Ouyang
Article Number: 5
Published online on: 23 October 2025

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Case Report Open Access

Brain metastasis of ovarian cancer >20 years after initial diagnosis: A case report

Chihiro Ishizawa, Kazunari Miyazawa, Misaki Tani, Kazuaki Neriishi, Yukari Kambe, Akira Tsuchiya
Article Number: 4
Published online on: 23 October 2025

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Article Open Access

Investigating the roles of microRNAs associated with cancer stem cells, drug resistance, metastasis and recurrence in hepatocellular carcinoma: A systematic review, network analysis and experimental verification

Yuanyuan Jiang, Xiaoning Zhu, Qinghua Peng, Paniz Zarghami Dastjerdi, Mengyun Peng, Ding Zheng, Xiaodong Wang, Yoke Kqueen Cheah, Jing Wang
Article Number: 3
Published online on: 23 October 2025

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Case Report Open Access

Advanced dual primary male breast cancer and lung cancer: A case report and literature review

Xiaoxiao Xing, Junyi Li, Yue Wang, Shiyun Zhang, Jun Li, Yun Wang, Dongpo Zhang, Daixiang Liao
Article Number: 2
Published online on: 22 October 2025

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Retraction Open Access

[Retracted] Tumor necrosis factor‑related apoptosis‑inducing ligand inhibits proliferation and induces apoptosis of prostate and bladder cancer cells

Lin Hao, Yan Zhao, Zhi-Gang Li, Hou-Guang He, Qing Liang, Zhi-Guo Zhang, Zhen-Duo Shi, Pei-Ying Zhang, Cong-Hui Han
Article Number: 1
Published online on: 22 October 2025

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Journal Cover
February-2026 Volume 31 Issue 2

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Tanshinone IIA targets RNF123 to inhibit non‑small cell lung cancer cell proliferation, migration and invasion via KAT2B‑mediated H3K18ac modification

Yongjie He, Yingxin Zhang, Jiangsheng Zhang, Kaican Cai
Article Number: 69
Published online on: 04 December 2025

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Article Open Access

Expression profiling reveals coordinated dysregulation of autophagy‑associated proteins in marginal zone lymphoma and therapeutic implications

Jingshu Ruan, Xin Zhou, Ai Li, Ningning Shan
Article Number: 68
Published online on: 03 December 2025

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Article Open Access

Analysis of the TCRβ repertoire characteristics when combining radiotherapy and immunotherapy in cancer

Xueli Yang, Wujun Wei, Zhihui Feng, Biao Zhang, Yi Liu, Fei Yang, Chong Zhang, Minglin Ou, Songbai Liao, Xianliang Hou
Article Number: 67
Published online on: 03 December 2025

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Article Open Access

Identification and validation of critical mitochondrial hub genes for prostate cancer

Sha Liu, Liang Huang, Li Lin, Hong Shan, Yueming Wan
Article Number: 66
Published online on: 03 December 2025

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Review Open Access

Roles of minimally invasive techniques in the management of epithelial ovarian cancer (Review)

Ruibing Yang, Jiali Gao, Yunyun Cheng, Caihong Lu, Juan Li
Article Number: 65
Published online on: 03 December 2025

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Case Report Open Access

Pregnancy with vitrified oocytes after fertility sparing surgery in a patient with fallopian tube cancer and a BRCA2 mutation: A case report and literature review

Guglielmo Stabile, Stefania Cicogna, Gabriella Zito, Anna Vido, Andrea Romano, Alessandro Mangogna, Luigi Nappi, Giuseppe Ricci
Article Number: 64
Published online on: 02 December 2025

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Retraction Open Access

[Retracted] Clinical significance and effect of Sam68 expression in gastric cancer

Jinzhang Xiao, Qiuhong Wang, Qichang Yang, Hua Wang, Fulin Qiang, Song He, Jin Cai, Lei Yang, Yingying Wang
Article Number: 63
Published online on: 02 December 2025

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Article Open Access

Genome‑wide CRISPR screening identifies CLDN1 as a central node in the anticancer mechanisms of berberine and as a therapeutic target in lung cancer

Xiaogang Wang, Benzhong Mi, Jinfeng Lv, Xin Tang, Jingyu Huang, Fei Liu, Yajing Xing, Xingjian Wen, Yongde Wang, Yadong Zhong
Article Number: 62
Published online on: 01 December 2025

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Article Open Access

Construction of a human epidermal growth factor receptor 2‑related gene risk model for predicting breast cancer prognosis

Limin Huang, Chunhong Xu, Yining Song, Furong Sun, Xuemei Sun, Hanyi Yao, Mingchen Liu, Nan Luo
Article Number: 61
Published online on: 01 December 2025

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Article Open Access

Development of a machine learning model for preoperative prediction of spread through air spaces in resectable 
non‑small cell lung cancer: A single‑center retrospective study

Chong Yang, Guozheng Ding, Bicheng Zhan, Lanlan Xuan, Feifei Cheng, Yanguo Yang
Article Number: 60
Published online on: 01 December 2025

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Case Report Open Access

Integrated diagnostic evaluation of multiple malignant neoplasms via 99mTc‑MDP three‑phase bone imaging: A case report

Jing-Yi Lian, Jian-Lin Lu, Hui-Yu Zheng, Si-Xia Yuan, Jin-Shan Zhang
Article Number: 59
Published online on: 01 December 2025

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Article

Retrospective analysis of the association between monocyte percentage and outcomes in newly diagnosed diffuse large B‑cell lymphoma

Chaoqiang Zheng, Xiaoqin Xin
Article Number: 58
Published online on: 28 November 2025

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Review Open Access

Role of HOXA transcript antisense RNA myeloid‑specific 1 in cancer (Review)

Yipei Jing, Xiaoqi Li, Ye Guo
Article Number: 57
Published online on: 28 November 2025

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Article Open Access

Differential gene expression analysis reveals signaling pathways of proliferation, angiogenesis and metastasis is associated with interferon suppression in advanced hypopharyngeal cancer cells

Chia-Wei Kao, Yen-Ping Yeh, Ting-Wen Chen, Min-Ying Lin, Jyh-Der Leu, Yi-Jang Lee
Article Number: 56
Published online on: 27 November 2025

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Case Report Open Access

Unicentric Castleman disease with paraneoplastic pemphigus and follicular dendritic cell sarcoma: A case report

Yukun Li, Fanchen Zeng, Zeyao Wang, Ganjian Zhao, Qi Zhou
Article Number: 55
Published online on: 27 November 2025

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Article Open Access

CRISPR/Cas9‑mediated claudin‑2 knockout in HCT116 cells reveals its key role in colorectal cancer progression

Rana A. Alghamdi, Maryam H. Al‑zahrani
Article Number: 54
Published online on: 27 November 2025

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Article Open Access

Comparative evaluation of microRNA detection in plasma, urine and liquid‑based cytology for high‑grade cervical intraepithelial neoplasia

Stéphanie Calfa, Ana Julia Aguiar De Freitas, Welinton Hirai, Júlio César Possati‑Resende, Rhafaela Lima Causin, Ricardo Dos Reis, Rui Manuel Reis, Márcia Maria Chiquitelli Marques
Article Number: 53
Published online on: 26 November 2025

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Case Report Open Access

Small intestinal SMARCA4‑deficient undifferentiated carcinoma with intussusception: A case report

Xiaoshan Cai, Shanshan Liu, Linqian Li, Yuming Zhang, Qin Guo, Ze Chen, Meihua Qu, Yubing Wang, Ben Yang, Xianwen Yue
Article Number: 52
Published online on: 26 November 2025

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Article Open Access

SENP5 acts as a downstream target of androgen receptor and contributes to prostate cancer growth

Ximin Chen, Xubo Gong, Jingcheng Zhang, Weiwei Liu
Article Number: 51
Published online on: 26 November 2025

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Retraction Open Access

[Retracted] Scutellarein suppresses Aβ‑induced memory impairment via inhibition of the NF‑κB pathway in vivo and in vitro

Xiao-Wei Huang, Yan Xu, Xin Sui, He Lin, Jia-Ming Xu, Dong Han, Dou-Dan Ye, Guang-Fu Lv, Yue-Xin Liu, Xiao-Bo Qu, Ming-Hua Duan
Article Number: 50
Published online on: 26 November 2025

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Article Open Access

Prognostic analysis and expression patterns of programmed cell death ligand 1 and BRAF V600E in esophageal neuroendocrine carcinoma

Chengcheng Zhang, Li Zheng, Binwen Xu, Guidong Shi, Maoyong Fu
Article Number: 49
Published online on: 25 November 2025

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Article

Evaluating computer‑assisted mandibular reconstruction: Outsourced vs. in‑house approaches

Sho Katsura, Yoshihiro Morita, Ryotaro Kakimoto, Tetsuo Miyamoto, Kana Kashima, Emiko Ogasa, Yoshio Ueno, Ayano Tobe‑Nishimoto, Satoko Kishimoto, Yuka Matsumiya‑Matsumoto, Akinori Takeshita, Kazuhide Matsunaga, Narikazu Uzawa
Article Number: 48
Published online on: 25 November 2025

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Case Report Open Access

Multiple primary central nervous system lymphoma in the ventricular system and interpeduncular cistern: A case report

Qing Ouyang, Bing Sun, Haodong Sun, Jianing Luo, Zhen Xu, Yuan Ma
Article Number: 47
Published online on: 25 November 2025

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Review Open Access

Exploration of immunotherapy modalities in stage III unresectable non‑small cell lung cancer (Review)

Jiayun Ma, Jun Jiang
Article Number: 46
Published online on: 25 November 2025

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Case Report

Massive breast fat necrosis with invasive breast cancer: A case report

Anjie Zhang, Linfeng Song, Xiyao Yang, Xu Chen, Binlin Tian, Yongzhe Li, Guoyuan Jiang, Lin Jiang
Article Number: 45
Published online on: 25 November 2025

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