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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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International Journal of Molecular Medicine

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
November-2017 Volume 40 Issue 5

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Journal Metrics

Impact Factor: 8.5

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

MicroRNA-132 induces temozolomide resistance and promotes the formation of cancer stem cell phenotypes by targeting tumor suppressor candidate 3 in glioblastoma Retraction in /10.3892/ijmm.2025.5517

Zhen-Xiu Cheng, Wen-Bo Yin, Zhong-Yu Wang
Pages: 1307-1314
Published online on: 07 September 2017

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Article Open Access

Eya2 overexpression promotes the invasion of human astrocytoma through the regulation of ERK/MMP9 signaling

Zhifeng Wen, Chuansheng Liang, Qichen Pan, Yunjie Wang
Pages: 1315-1322
Published online on: 13 September 2017

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Article Open Access

Analysis of dermal fibroblasts isolated from neonatal and child cleft lip and adult skin: Developmental implications on reconstructive surgery

Veronika Živicová, Lukáš Lacina, Rosana Mateu, Karel Smetana, Radana Kavková, Eliška Drobná Krejčí, Miloš Grim, Alena Kvasilová, Jiří Borský, Hynek Strnad, Miluše Hradilová, Jana Šáchová, Michal Kolář, Barbora Dvořánková
Pages: 1323-1334
Published online on: 07 September 2017

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Article Open Access

PKCζ as a promising therapeutic target for TNFα-induced inflammatory disorders in chronic cutaneous wounds

Jian Zhang, Xuekang Yang, Hongtao Wang, Bin Zhao, Xue Wu, Linlin Su, Songtao Xie, Yunchuan Wang, Jun Li, Jiaqi Liu, Mengdong Liu, Fu Han, Ting He, Wei Zhang, Ke Tao, Dahai Hu
Pages: 1335-1346
Published online on: 20 September 2017

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Article Open Access

Inhibitory effects of 17β-estradiol or a resveratrol dimer on hypoxia-inducible factor-1α in genioglossus myoblasts: Involvement of ERα and its downstream p38 MAPK pathways

Yuanyuan Li, Yuehua Liu, Yun Lu, Bingjiao Zhao
Pages: 1347-1356
Published online on: 07 September 2017

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Article Open Access

A support vector machine classifier for the prediction of osteosarcoma metastasis with high accuracy

Yunfei He, Jun Ma, Xiaojian Ye
Pages: 1357-1364
Published online on: 07 September 2017

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Article Open Access

Saponin-enriched extract of Asparagus cochinchinensis alleviates airway inflammation and remodeling in ovalbumin-induced asthma model

Ji-Eun Sung, Hyun-Ah Lee, Ji-Eun Kim, Woo-Bin Yun, Beum-Soo An, Seung-Yun Yang, Dong-Seob Kim, Chung-Yeoul Lee, Hee-Seob Lee, Chang-Joon Bae, Dae-Youn Hwang
Pages: 1365-1376
Published online on: 21 September 2017

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Article Open Access

Psoralen promotes the expression of cyclin D1 in chondrocytes via the Wnt/β-catenin signaling pathway

Wenwei Zheng, Pingdong Lin, Yuhuan Ma, Xiang Shao, Houhuang Chen, Da Chen, Xianxiang Liu, Xihai Li, Hongzhi Ye
Pages: 1377-1384
Published online on: 21 September 2017

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Article Open Access

Pathway and network-based analysis of genome-wide association studies and RT-PCR validation in polycystic ovary syndrome

Haoran Shen, Zhou Liang, Saihua Zheng, Xuelian Li
Pages: 1385-1396
Published online on: 20 September 2017

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Article Open Access

Phosphorylation of carboxypeptidase B1 protein regulates β-cell proliferation

Seong-Lan Yu, Seungyun Han, Hong Rye Kim, Jong Woo Park, Dong Il Jin, Jaeku Kang
Pages: 1397-1404
Published online on: 19 September 2017

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Article Open Access

Autophagy mediated by endoplasmic reticulum stress enhances the caffeine-induced apoptosis of hepatic stellate cells

Yongjian Li, Yunyang Chen, Haiyan Huang, Minmin Shi, Weiping Yang, Jie Kuang, Jiqi Yan
Pages: 1405-1414
Published online on: 20 September 2017

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Article Open Access

Negative pressure wound therapy: Regulating blood flow perfusion and microvessel maturation through microvascular pericytes

Zhanjun Ma, Zonghuan Li, Kangquan Shou, Chao Jian, Pengcheng Li, Yahui Niu, Baiwen Qi, Aixi Yu
Pages: 1415-1425
Published online on: 13 September 2017

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Article Open Access

Androgen-independent LNCaP cells are a subline of LNCaP cells with a more aggressive phenotype and androgen suppresses their growth by inducing cell cycle arrest at the G1 phase

Pan Yu, Xiuzhi Duan, Yue Cheng, Chunhua Liu, Yuhua Chen, Weiwei Liu, Binbin Yin, Xuchu Wang, Zhihua Tao
Pages: 1426-1434
Published online on: 07 September 2017

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Article Open Access

MicroRNA-7-5p regulates the proliferation and migration of intestinal epithelial cells by targeting trefoil factor 3 via inhibiting the phosphoinositide 3-kinase/Akt signalling pathway

Jing Guo, Lingfen Xu, Xu Teng, Mei Sun
Pages: 1435-1443
Published online on: 06 September 2017

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Article Open Access

Ferulic acid exerts neuroprotective effects against cerebral ischemia/reperfusion-induced injury via antioxidant and anti-apoptotic mechanisms in vitro and in vivo

Zhongkun Ren, Rongping Zhang, Yuanyuan Li, Yu Li, Zhiyong Yang, Hui Yang
Pages: 1444-1456
Published online on: 07 September 2017

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Article Open Access

Expression of ERCC1, RRM1, TUBB3 in correlation with apoptosis repressor ARC, DNA mismatch repair proteins and p53 in liver metastasis of colorectal cancer

Csaba Tóth, Farkas Sükösd, Erzsébet Valicsek, Esther Herpel, Peter Schirmacher, Marcus Renner, Christoph Mader, László Tiszlavicz, Jörg Kriegsmann
Pages: 1457-1465
Published online on: 14 September 2017

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Article Open Access

Runx3 is a key modulator during the epithelial-mesenchymal transition of alveolar type II cells in animal models of BPD

Haiping Yang, Jianhua Fu, Li Yao, Ana Hou, Xindong Xue
Pages: 1466-1476
Published online on: 14 September 2017

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Article Open Access

Fibroblast growth factor 21 protects rat cardiomyocytes from endoplasmic reticulum stress by promoting the fibroblast growth factor receptor 1-extracellular signal‑regulated kinase 1/2 signaling pathway

Pingping Liang, Lin Zhong, Lei Gong, Jiahui Wang, Yujie Zhu, Weifeng Liu, Jun Yang
Pages: 1477-1485
Published online on: 19 September 2017

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Article Open Access

Distal-less homeobox 5 is a master regulator of the osteogenesis of human mesenchymal stem cells

June Seok Heo, Seung Gwan Lee, Hyun Ok Kim
Pages: 1486-1494
Published online on: 19 September 2017

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Article Open Access

MAPK/p38 regulation of cytoskeleton rearrangement accelerates induction of macrophage activation by TLR4, but not TLR3

Hongjun Bian, Feifei Li, Wenwen Wang, Qi Zhao, Shanshan Gao, Jincai Ma, Xiao Li, Wanhua Ren, Chengyong Qin, Jianni Qi
Pages: 1495-1503
Published online on: 19 September 2017

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Article Open Access

TIM4-TIM1 interaction modulates Th2 pattern inflammation through enhancing SIRT1 expression

Tianyong Hu, Xiaoqin Fan, Li Ma, Jiangqi Liu, Yunli Chang, Pingchang Yang, Shuqi Qiu, Tao Chen, Litao Yang, Zhiqiang Liu
Pages: 1504-1510
Published online on: 25 September 2017

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Article Open Access

MicroRNA-135a is involved in podocyte injury in a transient receptor potential channel 1-dependent manner

Xianggui Yang, Dongming Wu, Hongfei Du, Fang Nie, Xueli Pang, Ying Xu
Pages: 1511-1519
Published online on: 25 September 2017

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Article

Structure-activity relationship of three synthesized benzimidazole-based oligosaccharides in human platelet activation Corrigendum in /10.3892/ijmm.2019.4423

Yi Chang, Wen-Hsien Hsu, Wen-Bin Yang, Thanasekaran Jayakumar, Tzu-Yin Lee, Joen-Rong Sheu, Wan-Jung Lu, Jiun-Yi Li
Pages: 1520-1528
Published online on: 13 September 2017

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Article

Comparison of HIF1A‑AS1 and HIF1A‑AS2 in regulating HIF‑1α and the osteogenic differentiation of PDLCs under hypoxia

Dongru Chen, Liping Wu, Lu Liu, Qimei Gong, Jinxuan Zheng, Caixia Peng, Jianqing Deng
Pages: 1529-1536
Published online on: 15 September 2017

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Article Open Access

Protective effects of heme oxygenase-1-transduced bone marrow-derived mesenchymal stem cells on reduced‑size liver transplantation: Role of autophagy regulated by the ERK/mTOR signaling pathway

Raorao Wang, Zhongyang Shen, Liu Yang, Mingli Yin, Weiping Zheng, Bin Wu, Tao Liu, Hongli Song
Pages: 1537-1548
Published online on: 06 September 2017

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Article

STAT3 mediates resistance to anoikis and promotes invasiveness of nasopharyngeal cancer cells

Chien-Hung Lin, Ming-Chang Chiang, Yann-Jang Chen
Pages: 1549-1556
Published online on: 25 September 2017

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Article

Physalis peruviana L. inhibits airway inflammation induced by cigarette smoke and lipopolysaccharide through inhibition of extracellular signal-regulated kinase and induction of heme oxygenase-1

Hyun Ah Park, Jae-Won Lee, Ok-Kyoung Kwon, Gilhye Lee, Yourim Lim, Jung Hee Kim, Jin-Hyub Paik, Sangho Choi, Imam Paryanto, Prasetyawan Yuniato, Doo-Young Kim, Hyung Won Ryu, Sei-Ryang Oh, Seung Jin Lee, Kyung-Seop Ahn
Pages: 1557-1565
Published online on: 15 September 2017

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Article

Triptolide blocks the STAT3 signaling pathway through induction of protein tyrosine phosphatase SHP-1 in multiple myeloma cells

Ji‑Hun Kim, Byoungduck Park
Pages: 1566-1572
Published online on: 06 September 2017

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Article

Effects of testosterone and 17β‑estradiol on angiotensin‑induced changes in tyrosine kinase activity in the androgen‑independent human prostate cancer cell line, DU145

Kamila Domińska, Antoni Kowalski, Tomasz Ochędalski, Elżbieta Rębas
Pages: 1573-1581
Published online on: 25 September 2017

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Article

Naringenin reduces oxidative stress and improves mitochondrial dysfunction via activation of the Nrf2/ARE signaling pathway in neurons

Kaihua Wang, Zhenzhen Chen, Longjian Huang, Bing Meng, Xinmei Zhou, Xiaodong Wen, Ding Ren
Pages: 1582-1590
Published online on: 13 September 2017

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Article

Carbon monoxide-releasing molecule suppresses inflammatory and osteoclastogenic cytokines in nicotine- and lipopolysaccharide-stimulated human periodontal ligament cells via the heme oxygenase-1 pathway

Ling Song, Jingyuan Li, Xiao Yuan, Wen Liu, Zhenggang Chen, Dawei Guo, Fang Yang, Qingyuan Guo, Hui Song
Pages: 1591-1601
Published online on: 08 September 2017

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Article

Protective effect of Rhizoma Dioscoreae extract against alveolar bone loss in ovariectomized rats via regulation of IL-6/STAT3 signaling

Zhi-Guo Zhang, Yan-Jing Chen, Li-Hua Xiang, Jing-Hua Pan, Zhen Wang, Gary Guishan Xiao, Da-Hong Ju
Pages: 1602-1610
Published online on: 08 September 2017

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Correction Open Access

[Corrigendum] Suppression of CUL4A attenuates TGF-β1-induced epithelial-to-mesenchymal transition in breast cancer cells

Yunshan Wang, Xiaoyan Liu, Hui Zheng, Qin Wang, Li An, Guangwei Wei
Pages: 1611-1611
Published online on: 14 September 2017

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Journal Cover
December-2026 Volume 58 Issue 6

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Journal Metrics

Impact Factor: 8.5

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Tracing the malignant trajectory of microplastics and nanoplastics: Biological pathways potentially implicated in carcinogenesis (Review)

Mary A. Vasilopoulou, Maria Adamaki, Panagiotis Zoumpourlis, Demetrios A. Spandidos, Dimosthenis Sarigiannis, Vassilis Zoumpourlis
Article Number: 376
Published online on: 10 November 2026

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Piezo1 in acute and critical illnesses: From mechanosensing to organ dysfunction (Review)

Li Zhang, Hong Gu, Yibin Zhu, Lulu Tang, Jiaxing An, Jiaxing Zhu, Hai Jin, Biguang Tuo
Article Number: 375
Published online on: 10 November 2026

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Transmembrane proteins across cellular membranes: Emerging roles in non‑cancerous diseases (Review)

Pei-Feng Liu, Chia-Hsuan Chang, Hsing-Hsiang Wang, Chih-Wen Shu, Yung-Fu Chang
Article Number: 374
Published online on: 09 November 2026

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Article Open Access

MEX3B leads to aberrant expression of VCAN, aggravating the thoracic aortic dissection by contributing to the phenotype transformation of VSMCs

Jianmao Hong, Bijun Xu, Shiqiang Wang, Fan He
Article Number: 373
Published online on: 06 November 2026

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Review Open Access

From crystals to damage: The emerging role of ferroptosis in calcium oxalate nephropathy (Review)

Zhu Wang, Changzhi Xu, Qiong Deng, Yin Zhang, Hui Liang
Article Number: 372
Published online on: 05 November 2026

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Article Open Access

Orm1 protects steatotic livers against ischaemia‑reperfusion injury by stabilising Prdx1 and activating the Pi3k/Akt axis

Yuming Wang, Ruidong Ding, Hailun Cai, Huan Liu, Yilin Wang, Xiangheng Cai, Jinzhen Cai
Article Number: 371
Published online on: 05 November 2026

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Article Open Access

Emodin ameliorates diabetic cardiomyopathy by regulating mitochondrial dynamics of fission and fusion and ferroptosis through the AHR‑Nrf2 pathway

Xinrou Yu, Haifei Lou, Jiedong Zhou, Hui Lin, Jinjing Yang, Jufang Chi
Article Number: 370
Published online on: 05 November 2026

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Review Open Access

Macrophage polarization reprogramming by resveratrol: A novel mechanism for protecting the intestinal mucosal barrier in sepsis (Review)

Yang Tan, Jin Xia, Chuan-Yun Qian, Mei-Xian Su, Shu-Ji Gao, Yan-Lin Zhu, Xiao-Yu Yang, Wei Zhang, Ming-Wei Liu
Article Number: 369
Published online on: 04 November 2026

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Harnessing the power of Scutellaria baicalensis: Advances in active compounds and their impact on skeletal system diseases (Review)

Weichao Sun, Yuqi Wu, Liangyu Chen, Yan Ni, Chunling Zhao, Wei Sun, Yinxing Cui, Qian Yi
Article Number: 368
Published online on: 04 November 2026

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Review Open Access

Protein S‑palmitoylation in T cell‑mediated antitumor immunity: Context‑dependent mechanisms and therapeutic opportunities (Review)

Shiting Wang, Rui Xu, Sikan Jin, Ting Yu, Ming Qin, Lin Xu, Xianyao Wang
Article Number: 367
Published online on: 04 November 2026

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Fatty acid‑binding proteins at the inflammation‑cancer interface: Isoform‑specific metabolic‑immune mechanisms and therapeutic implications (Review)

Young-Sool Hah, Young-Tae Ju, Seung-Jun Lee, Jeongyun Hwang, Seung-Jin Kwag
Article Number: 366
Published online on: 04 November 2026

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Review Open Access

Role of microglia in neuromyelitis optica (Review)

Yuan Zhang, Jian-Bin Hong, Ming-Wei Liu, Lin-Ming Zhang
Article Number: 365
Published online on: 03 November 2026

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Review Open Access

Roles of TRIM proteins in cardiovascular diseases: From pathogenesis to therapeutic targeting (Review)

Fengmei Wang, Zhibo Xing, Yujuan Gao, Yanhong Gai
Article Number: 364
Published online on: 02 November 2026

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Correction Open Access

[Corrigendum] S100A8‑targeting siRNA enhances arsenic trioxide‑induced myeloid leukemia cell death by down‑regulating autophagy

Liangchun Yang, Minghua Yang, Hong Zhang, Zhuo Wang, Yan Yu, Min Xie, Mingyi Zhao, Liying Liu, Lizhi Cao
Article Number: 363
Published online on: 02 November 2026

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Review Open Access

S100 proteins in kidney disease: Inflammatory biomarkers, pathogenic mechanisms and therapeutic prospects (Review)

Hongfei Wang, Zhaoyang Li, Qianqian Li, Yufang Ni, Lifeng Meng, Jianchun Li
Article Number: 362
Published online on: 30 October 2026

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Review

Mechanisms and therapeutic perspectives of mucosal glycosylation-innate immunity crosstalk in inflammatory bowel disease (Review)

Xiaowen Liu, Tao Zhang, Jiayi Jin, Yumeng Song, Mozhu Li, Haotong Zhong, Mingyue Cai, Siyuan Ding, Xiaowei Han
Article Number: 361
Published online on: 30 October 2026

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Review Open Access

Glycolysis in pulmonary fibrosis: From drivers to therapeutic opportunities (Review)

Changhong Yao, Huanyu Yang, Mengjia Han, Qi Xu
Article Number: 360
Published online on: 29 October 2026

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Correction Open Access

[Corrigendum] Exogenous spermine attenuates diabetic kidney injury in rats by inhibiting AMPK/mTOR signaling pathway

Xinying Zhang, Li Zhang, Zhe Chen, Siwei Li, Bingbing Che, Ningning Wang, Junting Chen, Changqing Xu, Can Wei
Article Number: 359
Published online on: 29 October 2026

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Emerging role of non‑coding RNAs in the progression of MASLD‑driven hepatocellular carcinoma (Review)

Weihua Zheng, Caiyan An, Long Xia, Hongquan Wang, Yumin Wang, Junjing Zhang
Article Number: 358
Published online on: 27 October 2026

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Targeting ferroptosis in metabolic dysfunction‑associated steatotic liver disease: From mechanisms to cell type‑specific therapeutic strategies (Review)

Xiang Tao, Mei Liu
Article Number: 357
Published online on: 26 October 2026

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Hormonal remodeling and molecular mechanisms in postmenopausal osteoporosis: Pathogenesis and therapeutic implications (Review)

Wenjun Liu, Zhengzheng Li, Penglin Wang, Jiahao Zeng, Haimin Zeng, Yining Xie, Ruhui Yang, Liu Yang, Sijian Lin, Chenyu Zhang
Article Number: 356
Published online on: 26 October 2026

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Correction Open Access

[Corrigendum] Apelin‑13 attenuates ER stress‑associated apoptosis induced by MPP+ in SH‑SY5Y cells 

Yunlu Jiang, Haiqing Liu, Bingyuan Ji, Zhengwen Wang, Chunmei Wang, Chunqing Yang, Yanyou Pan, Jing Chen, Baohua Cheng, Bo Bai
Article Number: 355
Published online on: 26 October 2026

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Review Open Access

Mechanisms and therapeutic implications of ferritinophagy in fibrotic diseases (Review)

Siying Sun, Jie Yu, Xuemei Li, Hongfei Liao
Article Number: 354
Published online on: 23 October 2026

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Review Open Access

Immune remodeling in inflammatory bowel disease-associated colorectal cancer: Mechanisms and immunotherapeutic implications (Review)

Tao Zhang, Zhetan Ren, Ling Wang, Ru Man, Lin Wang, Jing Wang, Xiaozhen Cheng, Jirun Peng, Yongduo Yu
Article Number: 353
Published online on: 22 October 2026

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Inflammatory regulatory mechanisms and targeted therapy of antineutrophil cytoplasmic antibodies in atherosclerosis (Review)

Jingjing Cui, Qi Cui, Jinying Dou, Xiaoyan Li, Wenlong Chang, Lanchun Shi, Liyun An
Article Number: 352
Published online on: 22 October 2026

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Article Open Access

HMGN5 promotes renal tubular inflammation and pyroptosis‑associated signaling in chronic kidney disease via the IFNAR2 axis

Xue Rong, Jing Xu, Jienan Zhang, Qi Zhang, Jiangli Wang, Guoxin Zhang, Limin Nie
Article Number: 351
Published online on: 22 October 2026

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Correction Open Access

[Corrigendum] Radiation induces primary osteocyte senescence phenotype and affects osteoclastogenesis in vitro

Yuyang Wang, Linshan Xu, Jianping Wang, Jiangtao Bai, Jianglong Zhai, Guoying Zhu
Article Number: 350
Published online on: 21 October 2026

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Transcription factors in liver fibrosis: Mechanistic insights and nanotechnology‑driven therapeutic strategies (Review)

Xianfei Zhou, Chongjun Yang, Zhiyong Weng, Lihua Li
Article Number: 349
Published online on: 21 October 2026

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From RNA fate to cancer state transitions: m5C‑driven metabolic and immune reprogramming (Review)

Yuanli Zhou, Bolv Zhu, Xingzhou Tang, Shuishui Yin
Article Number: 348
Published online on: 20 October 2026

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Correction Open Access

[Corrigendum] Dihydroartemisinin attenuates osteoclast formation and bone resorption via inhibiting the NF‑κB, MAPK and NFATc1 signaling pathways and alleviates osteoarthritis 

Dong Ding, Jiangbo Yan, Gangning Feng, Yong Zhou, Long Ma, Qunhua Jin
Article Number: 347
Published online on: 19 October 2026

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Review Open Access

Centrosomal protein 55: Research progress on biological characteristics, disease associations and clinical translational potential (Review)

Sanmei Nong, Qiudong Huang, Kuibo Huang, Xiao Luo, Yin Huang, Wenlian Zheng, Weiyi Huang, Zhaoyun Liu
Article Number: 346
Published online on: 16 October 2026

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Review Open Access

Multiple strategies to improve the therapeutic efficacy of mesenchymal stem cell‑derived exosome transplantation in ischemic stroke (Review)

Yan Xu, Xiaolei Zhou, Wenhui Zeng, Jiabing Wang, Lin Zhou, Lincai Li, Zhengwei Zou, Cixiang Chen, Yichi Zhang, Zhengyi He, Junsong Ye
Article Number: 345
Published online on: 14 October 2026

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Article Open Access

Resveratrol alleviates osteoarthritis progression by inhibiting NLRP3 inflammasome response via the AMPK/PPARγ signaling pathway

Shanshan Cui, Zifan Luo, Wen Qin, Bo Chen, Qiaoxia Zhang, Jianbing Ma, Jie Ma, Rui Zhang
Article Number: 344
Published online on: 14 October 2026

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Expression of Concern Open Access

[Expression of Concern] Anti‑metastatic and differential effects on protein expression of epigallocatechin‑3‑gallate in HCCLM6 hepatocellular carcinoma cells

Yunjuan Zhang, Lawrence Owusu, Wei Duan, Tao Jiang, Shizhu Zang, Ayaz Ahmed, Yi Xin
Article Number: 343
Published online on: 14 October 2026

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Article Open Access

Six3 promoting the migration and neural differentiation of BMSCs via Btg2‑mediated Akt signaling pathway activation: A therapeutic strategy for stroke

Zhenqiang Fu, Zhixin Li, Limin Zhang, Wentao Hu, Hecheng Yang, Jingtao Wang
Article Number: 342
Published online on: 12 October 2026

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Expression of Concern Open Access

[Expression of Concern] EETs and CYP2J2 inhibit TNF‑α‑induced apoptosis in pulmonary artery endothelial cells and TGF‑β1‑induced migration in pulmonary artery smooth muscle cells

Wenjing Feng, Xizhen Xu, Gang Zhao, Geng Li, Tiantian Liu, Junjie Zhao, Ruolan Dong, Dao Wen Wang, Ling Tu
Article Number: 341
Published online on: 12 October 2026

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Review Open Access

Gomisin A as a multi‑target therapeutic agent: Pharmacological mechanisms, pharmacokinetics and network pharmacology (Review)

Jiaqi Xu, Sha Shi, Chengkai Zhu, Qi Sui, Shanhao Zhu, Jingnan Zhang, Yi Zhang, Peng Chen
Article Number: 340
Published online on: 09 October 2026

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Review Open Access

Multi‑target mechanisms of paeoniflorin in inflammatory regulation: A network pharmacology (Review)

Jin Zhang, Junjie Ye, Kun Jin, Xuan Sun, Xinyu Yu, Yuan Zhao, Ni Zhu
Article Number: 339
Published online on: 09 October 2026

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Review Open Access

Mechanisms of neuroimmune crosstalk in vestibular disorders: Linking inflammation with neural circuit dysfunction (Review)

Xianfang Pan, Jin Fan, Zhiyi Yang, Zegang Yin, Zhen Li, Zhifeng Rui, Hujun Zhang, Yujie Li, Hongjuan Zhang
Article Number: 338
Published online on: 08 October 2026

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Expression of Concern Open Access

[Expression of Concern] Gambogic acid inhibits invasion of osteosarcoma via upregulation of TIMP‑1

Zeng-Feng Xin, Cheng-Chun Shen, Li-Jiang Tao, Shi-Gui Yan, Hao-Bo Wu
Article Number: 337
Published online on: 08 October 2026

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Anesthetics and cancer biology: Translational evidence from perioperative modulation to drug repurposing (Review)

Ting Yang, Jiao Tang, Muhammad Saqib Mudabbar, Huan Hu, Qiang Fu, Chunlan Pu
Article Number: 336
Published online on: 05 October 2026

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Expression of Concern Open Access

[Expression of Concern] Multiple roles of SOCS proteins: Differential expression of SOCS1 and SOCS3 in atherosclerosis

Xiao Liang, Ming He, Tao Chen, Yan Liu, Yu-Ling Tian, Yu-Liang Wu, Yan Zhao, Yan Shen, Zu-Yi Yuan
Article Number: 335
Published online on: 30 September 2026

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January-2027 Volume 59 Issue 1

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Journal Metrics

Impact Factor: 8.5

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Cellular and molecular mechanisms of arrhythmogenesis in Takotsubo syndrome (Review)

Danqi Xu, Xiaohong Chen, Maolin Hao, Qianqian Xu, Binbin Zhao, Wenjun Huang, Xiaobo Zhou, Qiang Xu, Huan Lan
Article Number: 5
Published online on: 12 November 2026

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Metabolic syndrome and Alzheimer's disease: Mechanistic links and precision prevention (Review)

Hanlu Chen, Tao Ding, Yifan Zhu, Mei Yang, Fangsheng Wang, Puwen Chen, Haihong Lin, Huapei Kang, Maohong Hu, Jun Zhou, Xiaoling Wang
Article Number: 4
Published online on: 12 November 2026

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Article Open Access

Irisin alleviates oxidative stress and osteoblast apoptosis in glucocorticoid-induced rat osteonecrosis of the femoral head via the integrin αVβ5/Bach1/Nrf2 signaling pathway

Xin Zhang, Yuankai Zhang, Yan Zhao, Keke Song, Xiaofei Liu, Kai Nan, Lihong Fan
Article Number: 3
Published online on: 12 November 2026

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Expression of Concern Open Access

[Expression of Concern] Downregulation of hepatic lipase is associated with decreased CD133 expression and clone formation in HepG2 cells

Xuehua Liu, Junhua Zuo, Yuan Fang, Jing Wen, Feihong Deng, Hui Zhong, Bo Jiang, Jide Wang, Biao Nie
Article Number: 2
Published online on: 11 November 2026

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Mitochondria‑associated small RNAs in breast cancer: An asymmetric evidence landscape from metabolic rewiring to immune selection (Review)

Hung-Yu Lin, Hui-Wen Ho, Hao-Wen Hsiao, Yi-Ru Shen, Hao-Yi Li, Pei-Yi Chu
Article Number: 1
Published online on: 10 November 2026

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