Journal Articles
Article
High glucose induces the proliferation of prostatic cells via downregulating MRE11
Chunwei Ye, Yi Cai, Qian Cai, Shunhui Yuan, Fan Huang, Xiaofang Yang, Shuchen He, Zhuoheng Li, Yanwen Wang, Delin Yang, Zhipeng Li
Pages: 3105-3114 Published online on: 07 March 2018
Article
SUMO2 modification of Aurora B and its impact on follicular development and atresia in the mouse ovary
Jing Cao, Xiao‑Ming Liu, Li‑Lin Huang, Li Wang, Xiao‑Fei Jiao, Li‑Jun Huo
Pages: 3115-3126 Published online on: 07 March 2018
Article
Triptolide reduces ischemia/reperfusion injury in rats and H9C2 cells via inhibition of NF‑κB, ROS and the ERK1/2 pathway
Bin Yang, Ping Yan, Guang‑Zhao Yang, Hui‑Li Cao, Fei Wang, Bao Li
Pages: 3127-3136 Published online on: 06 March 2018
Article
Inhibition effects of total flavonoids from Sculellaria barbata D. Don on human breast carcinoma bone metastasis via downregulating PTHrP pathway
Xiao Zheng, Wen Kang, Huihui Liu, Shanyu Guo
Pages: 3137-3146 Published online on: 27 February 2018
Article
miR‑377 targets CUL4A and regulates metastatic capability in ovarian cancer
Rufen Yu, Limei Cai, Yingui Chi, Xiangcui Ding, Xueqing Wu
Pages: 3147-3156 Published online on: 07 March 2018
Article
Deguelin exerts anticancer activity of human gastric cancer MGC-803 and MKN-45 cells in vitro
Wen Kang, Xiao Zheng, Ping Wang, Shanyu Guo
Pages: 3157-3166 Published online on: 05 March 2018
Article
REG3A overexpression suppresses gastric cancer cell invasion, proliferation and promotes apoptosis through PI3K/Akt signaling pathway
Yan-Song Qiu, Guang-Jun Liao, Ning-Ning Jiang
Pages: 3167-3174 Published online on: 28 February 2018
Article
Transplantation of human matrix metalloproteinase-1 gene-modified bone marrow-derived mesenchymal stem cell attenuates CCL4-induced liver fibrosis in rats
Chao Du, Mingde Jiang, Xiaolong Wei, Jianpin Qin, Hui Xu, Yunxia Wang, Yong Zhang, Dejiang Zhou, Hongli Xue, Shumei Zheng, Weizheng Zeng
Pages: 3175-3184 Published online on: 27 February 2018
Article
Intravenous administration of DPSCs and BDNF improves neurological performance in rats with focal cerebral ischemia
Xuemei Zhang, Yinglian Zhou, Hulun Li, Rui Wang, Dan Yang, Bing Li, Jin Fu
Pages: 3185-3194 Published online on: 28 February 2018
Article
Effect of lithocholic acid on biologically active α,β-unsaturated aldehydes induced by H2O2 in glioma mitochondria for use in glioma treatment
Dan Wang, Li Bie, Yanbin Su, Haoran Xu, Fengrong Zhang, Yanwen Su, Bo Zhang
Pages: 3195-3202 Published online on: 02 March 2018
Article
Biphasic activation of nuclear factor-κB and expression of p65 and c-Rel following traumatic neuronal injury
Huasheng Zhang, Dingding Zhang, Hua Li, Huiying Yan, Zihuan Zhang, Chenhui Zhou, Qiang Chen, Zhennan Ye, Chunhua Hang
Pages: 3203-3210 Published online on: 14 March 2018
Article
hTERT peptide fragment GV1001 demonstrates radioprotective and antifibrotic effects through suppression of TGF‑β signaling
Wei Chen, Ki‑Hyuk Shin, Sangjae Kim, Won‑Jun Shon, Reuben H. Kim, No‑Hee Park, Mo K. Kang
Pages: 3211-3220 Published online on: 14 March 2018
Article
MicroRNA-30e protects the heart against ischemia and reperfusion injury through autophagy and the Notch1/Hes1/Akt signaling pathway
Jianjie Zheng, Jing Li, Bo Kou, Qiuyue Yi , Tao Shi
Pages: 3221-3230 Published online on: 07 March 2018
Article
Mangiferin induces islet regeneration in aged mice through regulating p16INK4a
Hailian Wang, Xia He, Tiantian Lei, Yilong Liu, Guoli Huai, Minghan Sun, Shaoping Deng, Hongji Yang, Rongsheng Tong, Yi Wang
Pages: 3231-3242 Published online on: 01 March 2018
Article
PEDF improves cardiac function in rats subjected to myocardial ischemia/reperfusion injury by inhibiting ROS generation via PEDF‑R
Qixiang Zhao, Zhiwei Liu, Bing Huang, Yanliang Yuan, Xiucheng Liu, Hu Zhang, Fan Qiu, Yiqian Zhang, Yufeng Li, Haoran Miao, Hongyan Dong, Zhongming Zhang
Pages: 3243-3252 Published online on: 09 March 2018
Article
Aspirin modulates the inflammatory response in a thrombus‑stimulated LMVEC model
Lingcong Wang, Rongbiao Ying, Huifang Jiang, Qun Jin, Jing Kuang, Zhirong Zhang, Ying Shi, Danli Cai, Ruhui Yang
Pages: 3253-3266 Published online on: 13 March 2018
Article
Tree shrew neural stem cell transplantation promotes functional recovery of tree shrews with a hemi‑sectioned spinal cord injury by upregulating nerve growth factor expression
Liu‑Lin Xiong, Yu Zou, Yu Shi, Piao Zhang, Rong‑Ping Zhang, Xie‑Jie Dai, Bin Liu, Ting‑Hua Wang
Pages: 3267-3277 Published online on: 09 March 2018
Article
Trifluoperazine induces apoptosis through the upregulation of Bax/Bcl‑2 and downregulated phosphorylation of AKT in mesangial cells and improves renal function in lupus nephritis mice
Baodong Wang, Yankun Luo, Xiaoshuang Zhou, Rongshan Li
Pages: 3278-3286 Published online on: 13 March 2018
Article
RP105 alleviates myocardial ischemia reperfusion injury via inhibiting TLR4/TRIF signaling pathways
Jun Yang, Chaojun Yang, Jian Yang, Jiawang Ding, Xinxin Li, Qinqin Yu, Xin Guo, Zhixing Fan, Huibo Wang
Pages: 3287-3295 Published online on: 06 March 2018
Article
Expression of immunoglobulin G in human podocytes, and its role in cell viability and adhesion
Ziyang Jing, Hui Deng, Junfan Ma, Yanhong Guo, Yaoxian Liang, Rui Wu, Lata A, Zihan Geng, Xiaoyan Qiu, Yue Wang
Pages: 3296-3306 Published online on: 01 March 2018
Article
Effect of electro-acupuncture on the BDNF-TrkB pathway in the spinal cord of CCI rats
Wen-Zhan Tu, Si-Si Li, Xia Jiang, Xin-Ru Qian, Guan-Hu Yang, Peng-Peng Gu, Bin Lu, Song-He Jiang
Pages: 3307-3315 Published online on: 13 March 2018
Article
Cyclic mechanical tension reinforces DNA damage and activates the p53-p21-Rb pathway to induce premature senescence of nucleus pulposus cells
Chencheng Feng, Minghui Yang, Yang Zhang, Minghong Lan, Bo Huang, Huan Liu, Yue Zhou
Pages: 3316-3326 Published online on: 28 February 2018
Article
Transcriptomic and proteomic analysis of potential therapeutic target genes in the liver of metformin‑treated Sprague‑Dawley rats with type 2 diabetes mellitus
Yitao Chen, Yangsheng Wu, Yuanxiao Yang, Zhiwei Xu, Junfeng Tong, Zheming Li, Xiaojie Zhou, Changyu Li
Pages: 3327-3341 Published online on: 06 March 2018
Article
Overexpression of adrenomedullin protects mesenchymal stem cells against hypoxia and serum deprivation‑induced apoptosis via the Akt/GSK3β and Bcl‑2 signaling pathways
Hongjin Si, Yao Zhang, Yuqing Song, Lili Li
Pages: 3342-3352 Published online on: 05 March 2018
Article
Juglanin suppresses fibrosis and inflammation response caused by LPS in acute lung injury
Ze-Wu Dong, Yu-Fang Yuan
Pages: 3353-3365 Published online on: 09 March 2018
Article
c-Myc regulates the CDK1/cyclin B1 dependent‑G2/M cell cycle progression by histone H4 acetylation in Raji cells Corrigendum in /10.3892/ijmm.2019.4318
Yan Yang, Kai Xue, Zhi Li, Wei Zheng, Weijie Dong, Jiazhe Song, Shijie Sun, Tonghui Ma, Wenzhe Li
Pages: 3366-3378 Published online on: 28 February 2018
Article
MicroRNA-155 inhibits the osteogenic differentiation of mesenchymal stem cells induced by BMP9 via downregulation of BMP signaling pathway
Hongxia Liu, Liang Zhong, Taixian Yuan, Sicheng Chen, Yiqing Zhou, Liqin An, Yangliu Guo, Mengtian Fan, Ya Li, Yanting Sun, Wang Li, Qiong Shi, Yaguang Weng
Pages: 3379-3393 Published online on: 01 March 2018
Article
PEDF protects cardiomyocytes by promoting FUNDC1‑mediated mitophagy via PEDF-R under hypoxic condition
Yufeng Li, Zhiwei Liu, Yiqian Zhang, Qixiang Zhao, Xiaoyu Wang, Peng Lu, Hao Zhang, Zhu Wang, Hongyan Dong, Zhongming Zhang
Pages: 3394-3404 Published online on: 06 March 2018
Article
Accelerated inflammation and oxidative stress induced by LPS in acute lung injury: Ιnhibition by ST1926
Zewu Dong, Yufang Yuan
Pages: 3405-3421 Published online on: 19 March 2018
Article
Transcriptome and alternative splicing analysis of nucleus pulposus cells in response to high oxygen tension: Involvement of high oxygen tension in the pathogenesis of intervertebral disc degeneration
Chencheng Feng, Yang Zhang, Minghui Yang, Minghong Lan, Bo Huang, Huan Liu, Yue Zhou
Pages: 3422-3432 Published online on: 28 February 2018
Article
Valproic acid prevents glucocorticoid‑induced osteonecrosis of the femoral head of rats
Ding Zhou, Yi‑Xuan Chen, Jun‑Hui Yin, Shi‑Cong Tao, Shang‑Chun Guo, Zhan‑Ying Wei, Yong Feng, Chang‑Qing Zhang
Pages: 3433-3447 Published online on: 06 March 2018
Article
MCMV triggers ROS/NLRP3-associated inflammasome activation in the inner ear of mice and cultured spiral ganglion neurons, contributing to sensorineural hearing loss
Wei Zhuang, Caiji Wang, Xi Shi, Shiwei Qiu, Shili Zhang, Bing Xu, Min Chen, Wen Jiang, Hongyan Dong, Yuehua Qiao
Pages: 3448-3456 Published online on: 06 March 2018
Article
Ephrin‑b3 modulates hippocampal neurogenesis and the reelin signaling pathway in a pilocarpine‑induced model of epilepsy
Tian‑Tian Liu, Yi Li, Yi Shu, Bo Xiao, Li Feng
Pages: 3457-3467 Published online on: 07 March 2018
Article
miR-124/MCP-1 signaling pathway modulates the protective effect of itraconazole on acute kidney injury in a mouse model of disseminated candidiasis
Xiao‑Yue Li, Yu‑Qi Zhang, Gang Xu, Shao‑Hong Li, Heng Li
Pages: 3468-3476 Published online on: 13 March 2018
Article
Microarray analysis of the expression profile of lncRNAs reveals the key role of lncRNA BC088327 as an agonist to heregulin‑1β‑induced cell proliferation in peripheral nerve injury
Houlei Wang, Jingping Wu, Xinchao Zhang, Lei Ding, Qingmin Zeng
Pages: 3477-3484 Published online on: 15 March 2018
Article
Daidzein exerts anticancer activity towards SKOV3 human ovarian cancer cells by inducing apoptosis and cell cycle arrest, and inhibiting the Raf/MEK/ERK cascade Retraction in /10.3892/ijmm.2021.4929
Fu Hua, Chang‑Hua Li, Xiao‑Gang Chen, Xiao‑Ping Liu
Pages: 3485-3492 Published online on: 05 March 2018
Article
3,5,4'-Tri-O-acetylresveratrol attenuates seawater inhalation-induced acute respiratory distress syndrome via thioredoxin 1 pathway
Yilin Zhao, Lijie Ma, Ruixuan Wang, Tingting Chen, Xueying Liu, Faguang Jin
Pages: 3493-3500 Published online on: 01 March 2018
Article
CFTR ameliorates high glucose-induced oxidative stress and inflammation by mediating the NF-κB and MAPK signaling pathways in endothelial cells
Yang Fei, Liqin Sun, Chungang Yuan, Min Jiang, Qinhua Lou, Yan Xu
Pages: 3501-3508 Published online on: 07 March 2018
Article
Cardioprotective effect of rosuvastatin against isoproterenol-induced myocardial infarction injury in rats
Ying Yu, Lin Jin, Yamin Zhuang, Yan Hu, Jing Cang, Kefang Guo
Pages: 3509-3516 Published online on: 15 March 2018
Article
SIRT3 deficiency exacerbates p53/Parkin‑mediated mitophagy inhibition and promotes mitochondrial dysfunction: Implication for aged hearts
Yan Li, Ying Ma, Liqiang Song, Lu Yu, Le Zhang, Yingmei Zhang, Yuan Xing, Yue Yin, Heng Ma
Pages: 3517-3526 Published online on: 09 March 2018
Article
Selection of reference genes for expression analysis in mouse models of acute alcoholic liver injury
Sheng Wang, Jianqing Wang, Xiongwen Lv
Pages: 3527-3536 Published online on: 01 March 2018
Article
Identification of aberrantly expressed long non-coding RNAs in postmenopausal osteoporosis
Qi Fei, Xiaodong Bai, Jisheng Lin, Hai Meng, Yong Yang , Ai Guo
Pages: 3537-3550 Published online on: 19 March 2018
Article
Angiopoietin-2 promotes extracellular matrix degradation in human degenerative nucleus pulposus cells
Kun Wang, Liang Kang, Wei Liu, Yu Song, Xinghuo Wu, Yukun Zhang, Wenbin Hua, Kangcheng Zhao, Shuai Li, Ji Tu, Rongjin Luo, Cao Yang
Pages: 3551-3558 Published online on: 19 March 2018
Article
An adenosine A1R-A2aR imbalance regulates low glucose/hypoxia-induced microglial activation, thereby contributing to oligodendrocyte damage through NF-κB and CREB phosphorylation
Wen Huang, Shunjie Bai, Xuzheng Zuo, Weiju Tang, Pengfei Chen, Xiuying Chen, Gong Wang, Haoxiang Wang, Peng Xie
Pages: 3559-3569 Published online on: 07 March 2018
Article
Secoisolariciresinol diglucoside prevents the oxidative stress-induced apoptosis of myocardial cells through activation of the JAK2/STAT3 signaling pathway
Guiqiong Huang, Xiaofang Huang, Min Liu, Yue Hua, Bo Deng, Wen Jin, Wen Yan, Zhangbin Tan, Yifen Wu, Bin Liu, Yingchun Zhou
Pages: 3570-3576 Published online on: 13 March 2018
Article
The deficiency of CX3CL1/CX3CR1 system ameliorates high fructose diet-induced kidney injury by regulating NF-κB pathways in CX3CR1-knock out mice
Yong-Wu Yu, Ming-Xu Li, Zhi-Yong Zhang, Hai Yu
Pages: 3577-3585 Published online on: 16 March 2018
Article
Enhanced rapamycin delivery to hemangiomas by lipid polymer nanoparticles coupled with anti-VEGFR antibody
Haitao Li, Yunfei Teng, Xia Xu, Jianyong Liu
Pages: 3586-3596 Published online on: 28 February 2018
Article
Screening pathogenic genes in oral squamous cell carcinoma based on the mRNA expression microarray data
Yang Ding, Pengfei Liu, Shengsheng Zhang, Lin Tao, Jianmin Han
Pages: 3597-3603 Published online on: 27 February 2018
Article
Interfering RNA with multi-targets for efficient gene suppression in HCC cells
Tiejun Li, York Yuanyuan Zhu, Yi Ji, Songfeng Zhou
Pages: 3604-3610 Published online on: 09 March 2018
Article
Isolation, culture and biological characteristics of multipotent porcine tendon-derived stem cells
Jinjuan Yang, Qianjun Zhao, Kunfu Wang, Caiyun Ma, Hao Liu, Yingjie Liu, Weijun Guan
Pages: 3611-3619 Published online on: 07 March 2018
Article
In vivo effects of the NLRP1/NLRP3 inflammasome pathway on latent respiratory virus infection
Yong‑Huai Li, Xiang Wei, Shuang Ji, Shu‑Yu Gui, Su‑Mei Zhang
Pages: 3620-3628 Published online on: 28 February 2018
Article
Low expression of PTEN is essential for maintenance of a malignant state in human gastric adenocarcinoma via upregulation of p‑AURKA mediated by activation of AURKA
Liwei Li, Yue Song, Qing Liu, Xi Liu, Rui Wang, Chunsheng Kang, Qingyu Zhang
Pages: 3629-3641 Published online on: 07 March 2018
Article
Rhododendron album Blume extract inhibits TNF-α/IFN-γ-induced chemokine production via blockade of NF-κB and JAK/STAT activation in human epidermal keratinocytes
Ji‑Won Park, Han‑Sol Lee, Yourim Lim, Jin‑Hyub Paik, Ok‑Kyoung Kwon, Jung‑Hee Kim, Imam Paryanto, Prasetyawan Yunianto, Sangho Choi, Sei‑Ryang Oh, Kyung‑Seop Ahn
Pages: 3642-3652 Published online on: 09 March 2018
Article
Hydrogen ameliorates oxidative stress via PI3K-Akt signaling pathway in UVB-induced HaCaT cells
Bingxin Zhang, Zishen Zhao, Xiaoyin Meng, Hongguang Chen, Guojun Fu, Keliang Xie
Pages: 3653-3661 Published online on: 07 March 2018
Article
Novel mutations of the SERPINF1 and FKBP10 genes in Chinese families with autosomal recessive osteogenesis imperfecta
Hao Zhang, Yang Xu, Hua Yue, Chun Wang, Jiemei Gu, Jinwei He, Wenzhen Fu, Weiwei Hu, Zhenlin Zhang
Pages: 3662-3670 Published online on: 07 March 2018
Article
Incorporation of CD40 ligand enhances the immunogenicity of tumor‑associated calcium signal transducer 2 virus‑like particles against lung cancer
Wang Xi, Dong Ke, Long Min, Wang Lin, Zuo Jiahui, Lin Fang, Gao Zhaowei, Zhang Zhe, Chen Xi, Zhang Huizhong
Pages: 3671-3679 Published online on: 15 March 2018
Article
Islet-1 promotes the proliferation and invasion, and inhibits the apoptosis of A375 human melanoma cells
Xiaoling Zhu, Yuzhen Li, Qinggang Meng
Pages: 3680-3690 Published online on: 14 March 2018
Article
Simvastatin induces apoptosis in PTEN‑haploinsufficient lipoma cells
Franziska Kässner, Tina Sauer, Melanie Penke, Sandy Richter, Kathrin Landgraf, Antje Körner, Wieland Kiess, Norman Händel, Antje Garten
Pages: 3691-3698 Published online on: 14 March 2018
Article
MicroRNA-130a regulates chondrocyte proliferation and alleviates osteoarthritis through PTEN/PI3K/Akt signaling pathway
Yun Zhang, Shaochen Xu, Eric Huang, Haichao Zhou, Bing Li, Chenni Shao, Yunfeng Yang
Pages: 3699-3708 Published online on: 09 March 2018
Article
Anti-inflammatory effects of Passiflora foetida L. in LPS-stimulated RAW264.7 macrophages
Ji-Won Park, Ok-Kyoung Kwon, Hyung Won Ryu, Jin-Hyub Paik, Imam Paryanto, Prasetyawan Yuniato, Sangho Choi, Sei-Ryang Oh, Kyung-Seop Ahn
Pages: 3709-3716 Published online on: 12 March 2018
Article
Inhibitory effects of bee venom on mast cell-mediated allergic inflammatory responses
Yun‑Mi Kang, Kyung‑Sook Chung, In‑Hoon Kook, Yoon‑Bum Kook, Hyunsu Bae, Minho Lee, Hyo‑Jin An
Pages: 3717-3726 Published online on: 12 March 2018
Article
A novel psoralen derivative-MPFC enhances melanogenesis via activation of p38 MAPK and PKA signaling pathways in B16 cells
Li Yin, Guangxian Pang, Chao Niu, Maidina Habasi, Jun Dou, Haji Akber Aisa
Pages: 3727-3735 Published online on: 02 March 2018
Retraction