Journal Articles

Open Access

Treatment outcomes and prognostic factors of intrahepatic cholangiocarcinoma

Renumathy Dhanasekaran, Alan W. Hemming, Ivan Zendejas, Thomas George, David R. Nelson, Consuelo Soldevila-Pico, Roberto J. Firpi, Giuseppe Morelli, Virginia Clark, Roniel Cabrera

Pages: 1259-1267 Published online on: 18 February 2013
Open Access

Characterization of phosphodiesterase 2A in human malignant melanoma PMP cells

Hiroshi Morita, Taku Murata, Kasumi Shimizu, Kenya Okumura, Madoka Inui, Toshiro Tagawa

Pages: 1275-1284 Published online on: 31 January 2013
Open Access

Correlation of adverse effects of cisplatin administration in patients affected by solid tumours: A retrospective evaluation

Laura Astolfi, Sara Ghiselli, Valeria Guaran, Milvia Chicca, Edi Simoni, Elena Olivetto, Giorgio Lelli, Alessandro Martini

Pages: 1285-1292 Published online on: 06 February 2013
Open Access

Sleeping Beauty transposon system harboring HRAS, c-Myc and shp53 induces sarcomatoid carcinomas in mouse skin

Sunyoung Jung, Simon Weonsang Ro, Geunyoung Jung, Hye-Lim Ju, Eun-Sil Yu, Woo-Chan Son

Pages: 1293-1298 Published online on: 31 January 2013
Open Access

Genomic and phenotypic profiles of two Brazilian breast cancer cell lines derived from primary human tumors

Natássia C.R. Corrêa, Hellen Kuasne, Jerusa A.Q.A. Faria, Ciça C.S. Seixas, Iria G.D. Santos, Francine B. Abreu, Suely Nonogaki, Rafael M. Rocha, Gerluza Aparecida Borges Silva, Helenice Gobbi, Silvia R. Rogatto, Alfredo M. Goes, Dawidson A. Gomes

Pages: 1299-1307 Published online on: 12 February 2013
Open Access

Aberrant methylation of LINE-1, SLIT2, MAL and IGFBP7 in non-small cell lung cancer

Makoto Suzuki, Kenji Shiraishi, Ayami Eguchi, Koei Ikeda, Takeshi Mori, Kentaro Yoshimoto, Yasuomi Ohba, Tatsuya Yamada, Takaaki Ito, Yoshifumi Baba, Hideo Baba

Pages: 1308-1314 Published online on: 31 January 2013
Open Access

Method for the validation of immunohistochemical staining using SCID mouse xenografts: Expression of CD40 and CD154 in human non-small cell lung cancer

Keidai Ishikawa, Masaki Miyamoto, Tatsuya Yoshioka, Masatoshi Kadoya, Li  Li, Roshan Mishra, Kazuomi Ichinokawa, Yasuhito Shoji, Yoshiyuki Matsumura, Yasuhiro Hida, Kichizo Kaga, Tatsuya Kato, Mitsuhito Kaji, Toshiro Ohbuchi, Tomoo Itoh, Hirotoshi Dosaka-Akita, Yoshiro Matsui, Satoshi Hirano

Pages: 1315-1321 Published online on: 05 February 2013

Role of enolase-1 in response to hypoxia in breast cancer: Exploring the mechanisms of action

Jie Gao, Rongrong Zhao, Yan Xue, Zuoxing Niu, Kai Cui, Fachang Yu, Bo Zhang, Sheng Li

Pages: 1322-1332 Published online on: 01 February 2013

Harmol induces autophagy and subsequent apoptosis in U251MG human glioma cells through the downregulation of survivin

Akihisa Abe, Hiroko Kokuba

Pages: 1333-1342 Published online on: 18 January 2013

Silibinin inhibits TPA-induced cell migration and MMP-9 expression in thyroid and breast cancer cells

Soo-Jin Oh, Seung Pil Jung, Jeonghun Han, Sangmin Kim, Jee Soo Kim, Seok Jin Nam, Jeong Eon Lee, Jung-Han Kim

Pages: 1343-1348 Published online on: 24 January 2013

Knockdown of Dkk-3 decreases cancer cell migration and invasion independently of the Wnt pathways in oral squamous cell carcinoma‑derived cells

Naoki Katase, Mathieu Lefeuvre, Hidetsugu Tsujigiwa, Masae Fujii, Satoshi Ito, Ryo Tamamura, Rosario Rivera Buery, Mehmet Gunduz, Hitoshi Nagatsuka

Pages: 1349-1355 Published online on: 24 January 2013

Expression of death receptor-3 in human breast cancer and its functional effects on breast cancer cells in vitro

Zhicheng Ge, Andrew J. Sanders, Lin Ye, Robert E. Mansel, Wen G. Jiang

Pages: 1356-1364 Published online on: 30 January 2013

20-O-(β-D-glucopyranosyl)-20(S)-protopanaxadiol induces apoptosis via induction of endoplasmic reticulum stress in human colon cancer cells

Rui Zhang, Young Chung, Hee Sun Kim, Dong Hyun Kim, Hye Sun Kim, Weon Young Chang, Jin Won Hyun

Pages: 1365-1370 Published online on: 04 February 2013

Antitumor properties of salinomycin on cisplatin-resistant human ovarian cancer cells in vitro and in vivo: involvement of p38 MAPK activation

Bei Zhang, Xueya Wang, Fengfeng Cai, Weijie Chen, Uli Loesch, Xiao Yan Zhong

Pages: 1371-1378 Published online on: 17 January 2013

The saponin monomer of dwarf lilyturf tuber, DT-13, inhibits angiogenesis under hypoxia and normoxia via multi-targeting activity

Renping Zhao, Li Sun, Sensen Lin, Xianshu Bai, Boyang Yu, Shengtao Yuan, Luyong Zhang

Pages: 1379-1386 Published online on: 05 February 2013

Poly(amido amine) is an ideal carrier of miR-7 for enhancing gene silencing effects on the EGFR pathway in U251 glioma cells

Xiaozhi Liu, Gang Li, Zhiguo Su, Zhongmin Jiang, Lei Chen, Junfei Wang, Shizhu Yu, Zhenlin Liu

Pages: 1387-1394 Published online on: 11 February 2013

Downregulation of Src enhances the cytotoxic effect of temozolomide through AKT in glioma

Zengguang Wang, Jikui Sun, Xue Li, Shuyuan Yang, Shuyuan Yue, Jianning Zhang, Xuejun Yang, Tao Zhu, Rongcai Jiang, Weidong Yang

Pages: 1395-1398 Published online on: 17 January 2013

Alternative lengthening of telomeres is induced by telomerase inhibitors in Barrett's esophageal cells

Xiuguang Qin, Bo Qi, Baosheng Zhao

Pages: 1399-1404 Published online on: 17 January 2013

Effect of shRNA targeting mouse CD99L2 gene in a murine B cell lymphoma in vitro and in vivo

Fang Liu, Gong Zhang, Fanrong Liu, Xinhua Zhou, Xiaoyan Chen, Xiqun Han, Ziqing Wu, Tong Zhao

Pages: 1405-1414 Published online on: 18 January 2013

Expression profiles of microRNAs and their target genes in papillary thyroid carcinoma

Xin Liu, Mengzi He, Yufei Hou, Bing Liang, Longyu Zhao, Shumei Ma, Yaqin Yu, Xiaodong Liu

Pages: 1415-1420 Published online on: 31 January 2013

Crude saponins from Platycodon grandiflorum induce apoptotic cell death in RC-58T/h/SA#4 prostate cancer cells through the activation of caspase cascades and apoptosis-inducing factor

Ju-Hye Lee, Eun-Kyoung Oh, Hyun-Dong Cho, Jae-Yong Kim, Mi-Kyung Lee, Kwon-Il Seo

Pages: 1421-1428 Published online on: 29 January 2013

Reactive oxygen species regulate FSH-induced expression of vascular endothelial growth factor via Nrf2 and HIF1α signaling in human epithelial ovarian cancer

Zhenbo Zhang, Qianqian Wang, Jie Ma, Xiaofang Yi, Yaping Zhu, Xiaowei Xi, Youji Feng, Zhijun Jin

Pages: 1429-1434 Published online on: 06 February 2013

Suicide gene therapy for hepatocellular carcinoma cells by survivin promoter-driven expression of the herpes simplex virus thymidine kinase gene

Lili Qu, Yanyun Wang, Lailing Gong, Jin Zhu, Rujun Gong, Jin Si

Pages: 1435-1440 Published online on: 24 January 2013

Analysis of oncology research from 2001 to 2010: a scientometric perspective

Hongfang Shao, Qi Yu, Xiaoming Bo, Zhiguang Duan

Pages: 1441-1452 Published online on: 17 January 2013

Bone metastases in gastric cancer follow a RANKL-independent mechanism

Lucia D'Amico, Maria Antonietta Satolli, Caterina Mecca, Anna Castiglione, Manuela Ceccarelli, Patrizia D'Amelio, Mauro Garino, Maurizio De Giuli, Sergio Sandrucci, Riccardo Ferracini, Ilaria Roato

Pages: 1453-1458 Published online on: 06 February 2013

Hsp27: A novel therapeutic target for pediatric M4/M5 acute myeloid leukemia

Liangchun Yang, Lizhi Cao, Minghua Yang, Daolin Tang, Rui Kang, Xie Min, Shan Zhu, Yan Yu

Pages: 1459-1466 Published online on: 05 February 2013

Wwox expression may predict benefit from adjuvant tamoxifen in randomized breast cancer patients

Anna Göthlin Eremo, Pia Wegman, Olle Stål, Bo Nordenskjöld, Tommy Fornander, Sten Wingren

Pages: 1467-1474 Published online on: 31 January 2013

Quantitative detection of HER2 protein concentration in breast cancer tissue does not increase the number of patients eligible for adjuvant HER2-targeted therapy

Troels Bechmann, Dorte Aalund Olsen, Erik Hugger Jakobsen, Jonna Skov Madsen, Ivan Brandslund, Anne Marie Bak Jylling, Karina Dahl Steffensen, Anders Jakobsen

Pages: 1475-1482 Published online on: 15 February 2013

Suppression of CLIC4/mtCLIC enhances hydrogen peroxide-induced apoptosis in C6 glioma cells

Ye Xu, Jinsong Kang, Zhaoxin Yuan, Hongyan Li, Jing Su, Yang Li, Xiaoxia Kong, Hongyu Zhang, Weiwei Wang, Liankun Sun

Pages: 1483-1491 Published online on: 31 January 2013

NP-1250, an ABCG2 inhibitor, induces apoptotic cell death in mitoxantrone-resistant breast carcinoma MCF7 cells via a caspase-independent pathway

Masumi Ito, Kazunori Kajino, Masaaki Abe, Tsutomu Fujimura, Reiko Mineki, Takako Ikegami, Toshihisa Ishikawa, Okio Hino

Pages: 1492-1500 Published online on: 24 January 2013

Biological evaluation of 9-[(6-chloropyridin-4-yl)methyl]-9H-carbazole-3-carbinol as an anticancer agent

Chung-Hsien Liu, Chingju Lin, Kan-Jen Tsai, Yi-Ching Chuang, Ya-Ling Huang, Tsung-Hsien Lee, Li-Jiau Huang, Hsu-Chin Chan

Pages: 1501-1509 Published online on: 29 January 2013

Active immunotherapy for mouse breast cancer with irradiated whole-cell vaccine expressing VEGFR2

Heng-Xiu Yan, Ping Cheng, Hai-Yan Wei, Guo-Bo Shen, Li-Xin Fu, Jie Ni, Yang Wu, Yu-Quan Wei

Pages: 1510-1516 Published online on: 07 February 2013

Efficient downregulation of ErbB-2 induces TACC1 upregulation in breast cancer cell lines

Jinyu Xiang, Wensheng Qiu, Xingang Wang, Fang Zhou, Zhen Wang, Shihai Liu, Lu Yue

Pages: 1517-1523 Published online on: 24 January 2013

Concomitant overexpression of EGFR and CXCR4 is associated with worse prognosis in a new molecular subtype of non-small cell lung cancer

Alya A. Al Zobair, Barrak F. Al Obeidy, Lei Yang, Chunxu Yang, Yang Hui, Haijun Yu, Fang Zheng, Guifang Yang, Conghua Xie, Fuxiang Zhou, Yunfeng Zhou

Pages: 1524-1532 Published online on: 29 January 2013

MADD promotes the survival of human lung adenocarcinoma cells by inhibiting apoptosis

Wenxiang Bi, Yuping Wei, Jinxiang Wu, Gaoying Sun, Yuanfang Guo, Qiang Zhang, Liang Dong

Pages: 1533-1539 Published online on: 29 January 2013

Tetraarsenic oxide and cisplatin induce apoptotic synergism in cervical cancer

Jung Mi Byun, Dae Hoon Jeong, Dae Sim Lee, Joo Ran Kim, Sae Gwang Park, Mi Seon Kang, Young Nam Kim, Kyung Bok Lee, Moon Su Sung, Ki Tae Kim

Pages: 1540-1546 Published online on: 18 January 2013

Overexpression of p21-activated kinase 1 promotes endometrial cancer progression

Wen Lu, Jun-Jie Qu, Bi-Lan Li, Cong Lu, Qin Yan, Xiao-Mei Wu, Xiao-Yu Chen, Xiao-Ping Wan

Pages: 1547-1555 Published online on: 15 January 2013

Clinical significance of altered S100A2 expression in gastric cancer

Ying Zhao, Tian-Biao Zhang, Qiang Wang

Pages: 1556-1562 Published online on: 15 January 2013

Dose-dependent effect of tamoxifen in tamoxifen-resistant breast cancer cells via stimulation by the ERK1/2 and AKT signaling pathways

Li-Juan Wang, Su-Xia Han, E Bai, Xia Zhou, Meng Li, Gui-Hua Jing, Jing Zhao, An-Gang Yang, Qing Zhu

Pages: 1563-1569 Published online on: 21 January 2013

CD44v6 expression is related to mesenchymal phenotype and poor prognosis in patients with colorectal cancer

Seiya Saito, Hirohisa Okabe, Masayuki Watanabe, Takatsugu Ishimoto, Masaaki Iwatsuki, Yoshifumi Baba, Youhei Tanaka, Junji Kurashige, Yuji Miyamoto, Hideo Baba

Pages: 1570-1578 Published online on: 05 February 2013

Downregulated microRNA-200a promotes EMT and tumor growth through the wnt/β-catenin pathway by targeting the E-cadherin repressors ZEB1/ZEB2 in gastric adenocarcinoma

Ningning Cong, Ping Du, Anling Zhang, Fajuan Shen, Juan Su, Peiyu Pu, Tao Wang, Jie Zjang, Chunsheng Kang, Qingyu Zhang

Pages: 1579-1587 Published online on: 31 January 2013

Ubc9 promotes invasion and metastasis of lung cancer cells

Hui Li, Huiyan Niu, Yang Peng, Jiahe Wang, Ping He

Pages: 1588-1594 Published online on: 01 February 2013

Nestin is highly expressed in advanced-stage melanomas and neurotized nevi

Michiko Akiyama, Yoko Matsuda, Toshiyuki Ishiwata, Zenya Naito, Seiji Kawana

Pages: 1595-1599 Published online on: 15 February 2013

Terrein induces apoptosis in HeLa human cervical carcinoma cells through p53 and ERK regulation

Yuwarat Porameesanaporn, Wanlaya Uthaisang-Tanechpongtamb, Faongchat Jarintanan, Suchada Jongrungruangchok, Benjamas Thanomsub Wongsatayanon

Pages: 1600-1608 Published online on: 15 February 2013

Suppressive effects of an ethanol extract of Gleditsia sinensis thorns on human SNU-5 gastric cancer cells

Se-Jung Lee, Dong Hee Ryu, Lee Chan Jang, Seok-Cheol Cho, Wun-Jae Kim, Sung-Kwon Moon

Pages: 1609-1616 Published online on: 04 February 2013

Degradation of p53 by natural variants of the E6 protein of human papillomavirus type 16

Ja Woon Yi, Mi Jang, Sung Jin Kim, Sung Soon Kim, Jee Eun Rhee

Pages: 1617-1622 Published online on: 07 February 2013

Scutellaria barbata D. Don induces G1/S arrest via modulation of p53 and Akt pathways in human colon carcinoma cells

Lihui Wei, Jiumao Lin, Guangwen Wu, Wei Xu, Huang Li, Zhenfeng Hong, Jun Peng

Pages: 1623-1628 Published online on: 24 January 2013

Minimal residual disease monitoring in neuroblastoma patients based on the expression of a set of real-time RT-PCR markers in tumor-initiating cells

Tri Budi Hartomo, Aiko Kozaki, Daiichiro Hasegawa, Thi Van Huyen Pham, Nobuyuki Yamamoto, Atsuro Saitoh, Toshiaki Ishida, Keiichiro Kawasaki, Yoshiyuki Kosaka, Hiroki Ohashi, Tomoto Yamamoto, Satoru Morikawa, Satoshi Hirase, Ikuko Kubokawa, Takeshi Mori, Tomoko Yanai, Akira Hayakawa, Yasuhiro Takeshima, Kazumoto Iijima, Masafumi Matsuo, Hisahide Nishio, Noriyuki Nishimura

Pages: 1629-1636 Published online on: 12 February 2013

ABO blood groups and pancreatic cancer risk and survival: Results from the PANcreatic Disease ReseArch (PANDoRA) consortium

Cosmeri Rizzato, Daniele Campa, Raffaele Pezzilli, Pavel Soucek, William Greenhalf, Gabriele Capurso, Renata Talar-Wojnarowska, Anette Heller, Krzysztof Jamroziak, Kay-Tee Khaw, Tim J. Key, Franco Bambi, Stefano Landi, Beatrice Mohelnikova-Duchonova, Ludmila Vodickova, Markus W. Büchler, Peter Bugert, Pavel Vodicka, John P. Neoptolemos, Jens Werner, Jörg D. Hoheisel, Andrea S. Bauer, Nathalia Giese, Federico Canzian

Pages: 1637-1644 Published online on: 12 February 2013

Comparison of single-, double- and triple-combined testing, including Pap test, HPV DNA test and cervicography, as screening methods for the detection of uterine cervical cancer

Ju Hee Kim, In-Wook Kim, Yong-Wan Kim, Dong Chun Park, Yong Wook Kim, Keun-Ho Lee, Tae-Gyu Ahn, Sei-Jun Han, Woong Shick Ahn

Pages: 1645-1651 Published online on: 29 January 2013

microRNA-16 represses colorectal cancer cell growth in vitro by regulating the p53/survivin signaling pathway

Qunying Ma, Xinying Wang, Zhao Li, Bingsheng Li, Fengli Ma, Liang Peng, Yu Zhang, Angao Xu, Bo Jiang

Pages: 1652-1658 Published online on: 31 January 2013

Double inhibition of NF-κB and XIAP via RNAi enhances the sensitivity of pancreatic cancer cells to gemcitabine

Li-Ping Cao, Jian-Lin Song, Xiao-Ping Yi, Yi-Xiong Li

Pages: 1659-1665 Published online on: 23 January 2013

The molecular mechanism of action of aspirin, curcumin and sulforaphane combinations in the chemoprevention of pancreatic cancer

Arvind Thakkar, Dhruvitkumar Sutaria, B. Karthik Grandhi, Jeffrey Wang, Sunil Prabhu

Pages: 1671-1677 Published online on: 05 February 2013
Journal Cover

April 2013
Volume 29 Issue 4

Print ISSN: 1021-335X
Online ISSN: 1791-2431

Sign up for eToc alerts

Recommend to Library

Full Size Image