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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
April-2019 Volume 41 Issue 4

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

Overexpression of Opa interacting protein 5 increases the progression of liver cancer via BMPR2/JUN/CHEK1/RAC1 dysregulation

Yuwen Li, Fei Xiao, Wenting Li, Pingping Hu, Ruirui Xu, Jun Li, Guimei Li, Chuanlong Zhu
Pages: 2075-2088
Published online on: 11 February 2019

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Article Open Access

The underlying molecular mechanism and potential drugs for treatment in papillary renal cell carcinoma: A study based on TCGA and Cmap datasets

Jin‑Shu Pang, Zhe‑Kun Li, Peng Lin, Xiao‑Dong Wang, Gang Chen, Hai‑Biao Yan, Sheng‑Hua Li
Pages: 2089-2102
Published online on: 14 February 2019

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Article Open Access

MicroRNA‑92a promotes cell proliferation, migration and survival by directly targeting the tumor suppressor gene NF2 in colorectal and lung cancer cells

Krizelle Mae M. Alcantara, Reynaldo L. Garcia
Pages: 2103-2116
Published online on: 19 February 2019

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Article Open Access

TSPAN1 upregulates MMP2 to promote pancreatic cancer cell migration and invasion via PLCγ

Xiaobo Zhang, Gang Shi, Feng Gao, Peng Liu, Huaitao Wang, Xiaodong Tan
Pages: 2117-2125
Published online on: 30 January 2019

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Article Open Access

Adipose‑derived mesenchymal stem cells exhibit tumor tropism and promote tumorsphere formation of breast cancer cells

Yanqing Chen, Yunfan He, Xuecen Wang, Feng Lu, Jianhua Gao
Pages: 2126-2136
Published online on: 15 February 2019

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Article Open Access

Overexpression of BHLHE41, correlated with DNA hypomethylation in 3'UTR region, promotes the growth of human clear cell renal cell carcinoma

Zhouji Shen, Ling Zhu, Chao Zhang, Xiaobo Cui, Jun Lu
Pages: 2137-2147
Published online on: 07 February 2019

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Article Open Access

IL22 furthers malignant transformation of rat mesenchymal stem cells, possibly in association with IL22RA1/STAT3 signaling

Xiangrong Cui, Xuan Jing, Qin Yi, Zhongping Xiang, Jie Tian, Bin Tan, Jing Zhu
Pages: 2148-2158
Published online on: 11 February 2019

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Article Open Access

Polo‑like kinase 4 promotes tumorigenesis and induces resistance to radiotherapy in glioblastoma

Jia Wang, Jie Zuo, Maode Wang, Xudong Ma, Ke Gao, Xiaobin Bai, Ning Wang, Wanfu Xie, Hao Liu
Pages: 2159-2167
Published online on: 14 February 2019

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Article Open Access

Analysis of gene co‑expression network reveals prognostic significance of CNFN in patients with head and neck cancer

Baoling Liu, Guanhong Huang, Hongming Zhu, Zhaoming Ma, Xiaokang Tian, Li Yin, Xingya Gao, Xia He
Pages: 2168-2180
Published online on: 18 February 2019

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Article Open Access

Chlorophyllin e6‑mediated photodynamic therapy inhibits proliferation and induces apoptosis in human bladder cancer cells

Zhiyuan Zhuo, Zhenyu Song, Zhe Ma, Yuanfang Zhang, Guoxiong Xu, Gang Chen
Pages: 2181-2193
Published online on: 14 February 2019

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Article Open Access

In silico analysis identified miRNA‑based therapeutic agents against glioblastoma multiforme

Dan‑Dan Xiong, Wen‑Qing Xu, Rong‑Quan He, Yi‑Wu Dang, Gang Chen, Dian‑Zhong Luo
Pages: 2194-2208
Published online on: 19 February 2019

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Article Open Access

Reconstruction and analysis of circRNA‑miRNA‑mRNA network in the pathology of cervical cancer

Yuexiong Yi, Yanyan Liu, Wanrong Wu, Kejia Wu, Wei Zhang
Pages: 2209-2225
Published online on: 21 February 2019

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Article Open Access

miR‑146a‑5p targets TCSF and influences cell growth and apoptosis to repress NSCLC progression

Wen‑Ting Huang, Rong‑Quan He, Xiao‑Jiao Li, Jie Ma, Zhi‑Gang Peng, Jin‑Cai Zhong, Xiao‑Hua Hu, Gang Chen
Pages: 2226-2240
Published online on: 25 February 2019

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Article Open Access

Novel drug candidate for the treatment of several soft‑tissue sarcoma histologic subtypes: A computational method using survival‑associated gene signatures for drug repurposing

Xia Yang, Wen‑Ting Huang, Hua‑Yu Wu, Rong‑Quan He, Jie Ma, An‑Gui Liu, Gang Chen
Pages: 2241-2253
Published online on: 26 February 2019

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Article

Prostaglandin D2 expression is prognostic in high‑grade serous ovarian cancer

Mariana Rezende Alves, Nayra Soares Do Amaral, Fabio Albuquerque Marchi, Felipe Ilelis De Barros Silva, Alexandre André Balieiro Anastácio Da Costa, Kátia Cândido Carvalho, Glauco Baiocchi, Fernando Augusto Soares, Louise De Brot, Rafael Malagoli Rocha
Pages: 2254-2264
Published online on: 28 January 2019

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Article

Expression of protein disulfide isomerase A3 and its clinicopathological association in gastric cancer

Tomohiro Shimoda, Ryuichi Wada, Shoko Kure, Kousuke Ishino, Mitsuhiro Kudo, Ryuji Ohashi, Itsuo Fujita, Eiji Uchida, Hiroshi Yoshida, Zenya Naito
Pages: 2265-2272
Published online on: 05 February 2019

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Article

CADM2 inhibits human glioma proliferation, migration and invasion

Nan Liu, Chen Yang, Wansheng Bai, Zhen Wang, Xin Wang, Mark Johnson, Wenshi Wang, Pengxing Zhang, Hongwei Yang, Hui Liu, Yingduan Cheng, Yanyang Tu
Pages: 2273-2280
Published online on: 13 February 2019

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Article

ARHGAP6 regulates the proliferation, migration and invasion of lung cancer cells

Yongkai Wu, Ming Xu, Rong He, Ke Xu, Yegang Ma
Pages: 2281-2888
Published online on: 25 February 2019

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Article

Establishment and characterization of novel human oral squamous cell carcinoma cell lines from advanced‑stage tumors of buccal mucosa

Nilesh P. Gawas, Sushant S. Navarange, Gopal L. Chovatiya, Pankaj Chaturvedi, Sanjeev K. Waghmare
Pages: 2289-2298
Published online on: 07 February 2019

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Article

Expression and prognostic significance of insulin‑like growth factor-2 receptor in human hepatocellular carcinoma and the influence of transarterial chemoembolization

Anja Lautem, Frank Simon, Maria Hoppe‑Lotichius, Jens Mittler, Johanna  Vollmar, Arno Schad, Christoph Düber, Peter Robert Galle, Gerd Otto, Tim Zimmermann, Hauke Lang
Pages: 2299-2310
Published online on: 01 February 2019

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Article

Long non‑coding RNA linc00239 promotes malignant behaviors and chemoresistance against doxorubicin partially via activation of the PI3K/Akt/mTOR pathway in acute myeloid leukaemia cells

Yuting Yang, Wenshu Dai, Yingwei Sun, Ziyi Zhao
Pages: 2311-2320
Published online on: 31 January 2019

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Article

Icariin suppresses cell cycle transition and cell migration in ovarian cancer cells

Pengzhen Wang, Jinli Zhang, Xifeng Xiong, Wei Yuan, Shengnan Qin, Wenjuan Cao, Libing Dai, Fuqin Xie, Aiguo Li, Zhihe Liu
Pages: 2321-2328
Published online on: 28 January 2019

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Article

SPAG9/MKK3/p38 axis is a novel therapeutic target for liver cancer

Shudi Luo, Biqiong Ren, Guoying Zou, Junlong Liu, Wei Chen, Yiran Huang, Xing Chen, Yin Fu
Pages: 2329-2336
Published online on: 30 January 2019

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Article

SHIP1 inhibits cell growth, migration, and invasion in non‑small cell lung cancer through the PI3K/AKT pathway

Qiaofen Fu, Yuhui Huang, Chunlei Ge, Zhen Li, Hui Tian, Qiaolin Li, Hongshuai Li, Ruilei Li, Xingyu Tao, Yuanbo Xue, Ying Wang, Guanqin Yang, Weiyi Fang, Xin Song
Pages: 2337-2350
Published online on: 30 January 2019

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Article

Promoter hypermethylation of SOX11 promotes the progression of cervical cancer in vitro and in vivo

Xiaofang Li, Xiaoling Wu, Yun Li, Yumeng Cui, Run Tian, Namita Singh, Muyang Ding, Yang Yang, Yan'e Gao
Pages: 2351-2360
Published online on: 01 February 2019

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Article

MicroRNA‑144 suppresses aggressive phenotypes of tumor cells by targeting ANO1 in colorectal cancer

Yasu Jiang, Yunhui Cai, Weiwei Shao, Feng Li, Zongyu Guan, Yi Zhou, Chong Tang, Shichun Feng
Pages: 2361-2370
Published online on: 21 February 2019

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Article

Anti‑tissue factor antibody‑mediated immuno‑SPECT imaging of tissue factor expression in mouse models of pancreatic cancer

Aya Sugyo, Winn Aung, Atsushi B. Tsuji, Hitomi Sudo, Hiroki Takashima, Masahiro Yasunaga, Yasuhiro Matsumura, Tsuneo Saga, Tatsuya Higashi
Pages: 2371-2378
Published online on: 14 February 2019

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Article

The role of GDF15 in bone metastasis of lung adenocarcinoma cells

Lian Duan, Hai‑Lin Pang, Wen‑Jun Chen, Wei‑Wei Shen, Pei‑Pei Cao, Shu‑Mei Wang, Li‑Li Liu, He‑Long Zhang
Pages: 2379-2388
Published online on: 21 February 2019

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Article

LYPD8 regulates the proliferation and migration of colorectal cancer cells through inhibiting the secretion of IL‑6 and TNF‑α Corrigendum in /10.3892/or.2021.8004

Jianbin Xu, Jun Qian, Wei Zhang, Engeng Chen, Guolin Zhang, Gaoyang Cao, Fei Wang, Xuning Shen, Wei Zhou, Zhangfa Song
Pages: 2389-2395
Published online on: 26 February 2019

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Article

Low expression of AIM2 combined with high expression of p‑STAT3 is associated with poor prognosis in hypopharyngeal squamous cell carcinoma

Zhen Li, Xinli Shi, Hui Li, Weiyi Wang, Xiaoming Li
Pages: 2396-2408
Published online on: 25 February 2019

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Article

Bufotalin induces cell cycle arrest and cell apoptosis in human malignant melanoma A375 cells

Zhaohai Pan, Chuanjun Qu, Ying Chen, Xiaoyu Chen, Xiaona Liu, Wenjin Hao, Wenjuan Xu, Lei Ye, Peng Lu, Defang Li, Qiusheng Zheng
Pages: 2409-2417
Published online on: 26 February 2019

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Article

TNF‑α inhibits xenograft tumor formation by A549 lung cancer cells in nude mice via the HIF‑1α/VASP signaling pathway

Wen Liu, Xiang Chen, Yanqi He, Yihao Tian, Liu Xu, Yanbin Ma, Pengchao Hu, Ke Su, Zhenyu Luo, Lei Wei, Jingwei Zhang
Pages: 2418-2430
Published online on: 21 February 2019

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Article

Upregulation and hypomethylation of lncRNA AFAP1‑AS1 predicts a poor prognosis and promotes the migration and invasion of cervical cancer

Hao Bo, Liqing Fan, Zhaojian Gong, Zhizhong Liu, Lei Shi, Can Guo, Xiayu Li, Qianjin Liao, Wenling Zhang, Ming Zhou, Bo Xiang, Xiaoling Li, Guiyuan Li, Wei Xiong, Zhaoyang Zeng, Ke Cao, Shanshan Zhang, Fang Xiong
Pages: 2431-2439
Published online on: 21 February 2019

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Article

Expression profiles analysis identifies the values of carcinogenesis and the prognostic prediction of three genes in adrenocortical carcinoma

Zhipeng Gao, Xiaojun Man, Zhenhua Li, Jianbin Bi, Xiankui Liu, Zeliang Li, Yuyan Zhu, Zhe Zhang, Chuize Kong
Pages: 2440-2452
Published online on: 19 February 2019

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Article

Deoxypodophyllotoxin inhibits cell viability and invasion by blocking the PI3K/Akt signaling pathway in human glioblastoma cells Corrigendum in /10.3892/or.2023.8484 Retraction in /10.3892/or.2023.8605

Wei Wang, Wei Gao, Luyang Zhang, Dongyong Zhang, Zilong Zhao, Yijun Bao
Pages: 2453-2463
Published online on: 14 February 2019

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Article

Myristoylated alanine rich protein kinase C substrate is a potential cancer prognostic factor that regulates cell migration and invasion in glioblastoma

Wei Xiang, Tao Peng, Yang Ming, Shenjie Li, Ke Wang, Haorun Wang, Ligang Chen, Jie Zhou
Pages: 2464-2470
Published online on: 13 February 2019

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Article

CDCA3 is a potential prognostic marker that promotes cell proliferation in gastric cancer

Yan Zhang, Wei Yin, Wei Cao, Peisheng Chen, Longjun Bian, Qingfeng Ni
Pages: 2471-2481
Published online on: 12 February 2019

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Article

Multikinase inhibitor motesanib enhances the antitumor effect of cisplatin in cisplatin‑resistant human bladder cancer cells via apoptosis and the PI3K/Akt pathway

Jin‑Nyoung Ho, Seok‑Soo Byun, Sang Eun Lee, Je‑In Youn, Sangchul Lee
Pages: 2482-2490
Published online on: 11 February 2019

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Article

Association of CCL2, CCR2 and CCL5 genetic polymorphisms with the development and progression of benign prostatic hyperplasia

Yangyang Pang, Haoran Li, Yuwen Gong, Suoshi Jing, Cheng Peng, Wei Liu, Youli Zhao, Hanzhang Wang, Dharam Kaushik, Ronald Rodriguez, Zhiping Wang
Pages: 2491-2501
Published online on: 06 February 2019

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Article

Isoliquiritigenin inhibits the proliferation, apoptosis and migration of osteosarcoma cells

Chengjun Li, Xing Zhou, Chang Sun, Xiaozhou Liu, Xin Shi, Sujia Wu
Pages: 2502-2510
Published online on: 04 February 2019

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Article

MYC promotes the development of papillary thyroid carcinoma by inhibiting the expression of lncRNA PAX8‑AS1:28

Yi Zhang, Feilei Li, Jun Chen
Pages: 2511-2517
Published online on: 01 February 2019

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Article

CHAF1B promotes proliferation and reduces apoptosis in 95‑D lung cancer cells and predicts a poor prognosis in non‑small cell lung cancer

Yan Duan, Tanzhen Liu, Shengwen Li, Mingguang Huang, Xiaoyu Li, Hui Zhao, Jianqiang Li
Pages: 2518-2528
Published online on: 01 February 2019

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Article

Monocarboxylate transporter 1 is an independent prognostic factor in esophageal squamous cell carcinoma

Xue Chen, Xuan Chen, Fang Liu, Qianqian Yuan, Kaixian Zhang, Wei Zhou, Shanghui Guan, Yuanyuan Wang, Si Mi, Yufeng Cheng
Pages: 2529-2539
Published online on: 31 January 2019

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Article

MELK inhibition targets cancer stem cells through downregulation of SOX2 expression in head and neck cancer cells

Lili Ren, Boya Deng, Vassiliki Saloura, Jae‑Hyun Park, Yusuke Nakamura
Pages: 2540-2548
Published online on: 30 January 2019

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Article

Autophagy and apoptotic machinery caused by Polygonum cuspidatum extract in cisplatin‑resistant human oral cancer CAR cells

Yin‑Lai Wang, Chi‑Ting Horng, Min‑Tsang Hsieh, Hung‑Che Chen, Yu‑Syuan Huang, Jai‑Sing Yang, Guo‑Kai Wang, Jo‑Hua Chiang, Hul‑Han Chen, Chi‑Cheng Lu, Fu‑An Chen
Pages: 2549-2557
Published online on: 28 January 2019

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Article

Organic anion‑transporting polypeptides contribute to the uptake of curcumin and its main metabolites by human breast cancer cells: Impact on antitumor activity

Nattharat Jaerapong, Qurratul Ain Jamil, Juliane Riha, Daniela Milovanovic, Georg Krupitza, Bruno Stieger, Kanokwan Jarukomjorn, Walter Jäger
Pages: 2558-2566
Published online on: 14 February 2019

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Article

Tripartite motif‑containing 11 regulates the proliferation and apoptosis of breast cancer cells Corrigendum in /10.3892/or.2024.8838

Xianping Dai, Feng Geng, Mengshun Li, Ming Liu
Pages: 2567-2574
Published online on: 14 February 2019

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Article

NSPc1 polycomb protein complex binds and cross‑talks to lncRNAs in glioma H4 cells

Yuliang Wang, Zhikong Liang, Hui Li, Jinglong Tao, Yi Sun, Yanhua Gong
Pages: 2575-2584
Published online on: 05 February 2019

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Article

Cellular and radiobiological effects of carbonic anhydrase IX in human breast cancer cells

Antje Güttler, Katharina Theuerkorn, Anne Riemann, Henri Wichmann, Jacqueline Kessler, Oliver Thews, Matthias Bache, Dirk Vordermark
Pages: 2585-2594
Published online on: 05 February 2019

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Article

Inhibition of apoptosis by miR‑122‑5p in α‑fetoprotein‑producing gastric cancer

Suguru Maruyama, Shinji Furuya, Kensuke Shiraishi, Hiroki Shimizu, Ryo Saito, Hidenori Akaike, Naohiro Hosomura, Yoshihiko Kawaguchi, Hidetake Amemiya, Hiromichi Kawaida, Makoto Sudo, Shingo Inoue, Hiroshi Kono, Daisuke Ichikawa
Pages: 2595-2600
Published online on: 20 February 2019

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Correction Open Access

[Erratum] OBP‑801, a novel histone deacetylase inhibitor, induces M‑phase arrest and apoptosis in rhabdomyosarcoma cells

Chihiro Tomoyasu, Ken Kikuchi, Daisuke Kaneda, Shigeki Yagyu, Mitsuru Miyachi, Kunihiko Tsuchiya, Tomoko Iehara, Toshiyuki Sakai, Hajime Hosoi
Pages: 2601-2601
Published online on: 01 February 2019

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Journal Cover
January-2026 Volume 55 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Harnessing ferroptosis for cancer therapy: Mechanisms and therapeutic strategies (Review)

Nabil Mouawad, Nour El Jaafari, Mirvat El Sibai, Ralph J. Abi-Habib
Article Number: 24
Published online on: 24 November 2025

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Expression of Concern Open Access

[Expression of Concern] Promoter methylation of death‑associated protein kinase and its role in irradiation response in cervical cancer

Rebecca Ching-Yu Leung, Stephanie Si Liu, Kelvin Yuen-Kwong Chan, Kar-Fai Tam, Kar-Loen Chan, Ling-Chui Wong, Hextan Yuen-Sheung Ngan
Article Number: 23
Published online on: 24 November 2025

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Article Open Access

Oxaliplatin resistance in pancreatic ductal adenocarcinoma is non‑significantly mediated by diminished drug uptake but is highly linked to a poor apoptotic response to the cytotoxic threat

Hellen Röttgen, Lana Theurer, Teresa Peccerella, Ketaki Sandu, Johanna Weiss, Jürgen Burhenne, John P. Neoptolemos, Beate Köberle, Dirk Theile
Article Number: 22
Published online on: 19 November 2025

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Correction Open Access

[Corrigendum] Src homology phosphotyrosyl phosphatase 2 mediates cisplatin‑related drug resistance by inhibiting apoptosis and activating the Ras/PI3K/Akt1/survivin pathway in lung cancer cells

Chunlan Tang, Hu Luo, Dan Luo, Heping Yang, Xiangdong Zhou
Article Number: 21
Published online on: 19 November 2025

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S100B drives glioblastoma invasion and migration through TGF‑β2‑mediated epithelial‑mesenchymal transition

Xuemei Liao, Yuan Xu, Honghong Zhou, Qin Yi, Shifang Dong, Bin Tan
Article Number: 20
Published online on: 19 November 2025

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Review Open Access

Role of the SOX family in non‑small cell lung cancer: Molecular mechanisms and therapeutic implications (Review)

Kaiwei Wang, Yaoqi Li, Zhening Guo, Lin Song, Xiaoliang Ding, Linsheng Liu, Tao Hu, Yicong Bian, Chenrong Huang, Liyan Miao
Article Number: 19
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑18a enhances the radiosensitivity of cervical cancer cells by promoting radiation‑induced apoptosis

Sha Liu, Xiaofen Pan, Qin Yang, Lu Wen, Yao Jiang, Yingchao Zhao, Guiling Li
Article Number: 18
Published online on: 17 November 2025

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Review Open Access

Role of histone deacetylases in blood cancer: Exploring peptide‑based inhibitors as therapeutic strategies for leukemia treatment (Review)

Yaneenart Suwanwong, Phornthip Ploensil
Article Number: 17
Published online on: 14 November 2025

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The multidimensional regulatory network of the PD‑1/PD‑L1 axis in the esophageal squamous cell carcinoma microenvironment: Implications for novel combination therapies and precision immunotherapy (Review)

Haoyue Lai, Lu Qi, Zhixuan Lin, Zhongwen Li
Article Number: 16
Published online on: 13 November 2025

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Review Open Access

From modification to malignancy: Bridging acetylation mechanisms and therapeutic innovations in melanoma (Review)

Jingwen Wu, Xuxia Cai, Zimo Zhu, Xiahong Li, Kaoyuan Zhang, Chenchen Wu, Bo Yu, Cong Huang
Article Number: 15
Published online on: 12 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑92b promotes tumor growth and activation of NF‑κB signaling via regulation of NLK in oral squamous cell carcinoma

Zhiming Liu, Cynthia Diep, Tiantian Mao, Li Huang, Robert Merrill, Zhouwen Zhang, Youjian Peng
Article Number: 14
Published online on: 11 November 2025

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Article Open Access

C‑terminal HSP90 inhibitor NCT‑58 impairs the cancer stem‑like phenotype and enhances chemotherapy efficacy in TNBC

Eunsun Jung, Yoon-Jae Kim, Kyoungmin Lee, Seojin Jang, Soeun Park, Eunhye Oh, Minsu Park, Seongjae Kim, Dongmi Ko, Yong Koo Kang, Kee Dal Nam, Lee Farrand, Cong-Truong Nguyen, Minh Thanh La, Jihyae Ann, Jeewoo Lee, Ji Young Kim, Jae Hong Seo
Article Number: 13
Published online on: 11 November 2025

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Correction Open Access

[Corrigendum] Compound 225# inhibits the proliferation of human colorectal cancer cells by promoting cell cycle arrest and apoptosis induction

Xiaoxue Zhang, Liujun He, Yong Li, Yifei Qiu, Wujing Hu, Wanying Lu, Huihui Du, Donglin Yang
Article Number: 12
Published online on: 06 November 2025

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Immune system, inflammatory response, and regulated cell death in breast cancer research (Review)

Guangyao Li, Binghui Jin, Jialin Zhou, Shifeng Fang, Zhe Fan
Article Number: 11
Published online on: 05 November 2025

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Retraction Open Access

[Retracted] Uvangoletin induces mitochondria‑mediated apoptosis in HL‑60 cells in vitro and in vivo without adverse reactions of myelosuppression, leucopenia and gastrointestinal tract disturbances

Zhuanzhen Zheng, Zhenhua Qiao, Rong Gong, Yalin Wang, Yiqun Zhang, Yanping Ma, Li Zhang, Yujin Lu, Bo Jiang, Guoxia Li, Chunxia Dong, Wenliang Chen
Article Number: 10
Published online on: 03 November 2025

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Article Open Access

Characterization of the anticancer effect of mebendazole and its interaction with standard cytotoxic drugs in patient tumor cells ex vivo and in an in vivo mouse model

Sharmineh Mansoori, Kristin Blom, Claes Andersson, Mårten Fryknäs, Rolf Larsson, Peter Nygren
Article Number: 9
Published online on: 31 October 2025

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Correction Open Access

[Corrigendum] Gemcitabine combined with an engineered oncolytic vaccinia virus exhibits a synergistic suppressive effect on the tumor growth of pancreatic cancer

Wanyuan Chen, Weimin Fan, Guoqing Ru, Fang Huang, Xiaming Lu, Xin Zhang, Xiaozhou Mou, Shibing Wang
Article Number: 8
Published online on: 30 October 2025

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Article Open Access

CD44 knockdown and TGF‑β inhibition modulate cell proliferation and invasion in claudin‑low breast cancer cells

Ryoichi Matsunuma, Kazuo Kinoshita, Sae Imada, Shoko Sato, Ryosuke Hayami, Michiko Tsuneizumi
Article Number: 7
Published online on: 30 October 2025

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Retraction Open Access

[Retracted] MicroRNA‑302a targets GAB2 to suppress cell proliferation, migration and invasion of glioma

Jiuhong Ma, Jia Yu, Jingmei Liu, Xing Yang, Miao Lou, Jinghui Liu, Fuqiang Feng, Peigang Ji, Liang Wang
Article Number: 6
Published online on: 27 October 2025

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Article Open Access

LRRC59 inhibits perk pathway‑induced apoptosis and promotes cell proliferation, migration and invasion in colorectal cancer cells

Xingdong Hou, Yuting Wang, Yuzhuo Chen, Peiyan Zhong, Guangzhi Wang, Baicheng Li, Bowei Lu, Hanyu Jiang, Shili Ning
Article Number: 5
Published online on: 23 October 2025

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Article Open Access

Comparative analysis of the efficacy and safety of antibody‑drug conjugates, radionuclide‑drug conjugates and their combination targeting claudin 18.2 in gastric cancer treatment

Huan Du, Xiao-Fei Hao, Bin-Wei Lin, Yu Zhang, Luo Rui, Jing Wang, Ming-Ming Tang, De-Cai Wang, Yi-Han Zhu, Jie Li, Tang-Zhi Dai, Yuchuan Yang, Xia Yang, Xiaobo Du
Article Number: 4
Published online on: 22 October 2025

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Expression of Concern Open Access

[Expression of Concern] CDKN3 is an independent prognostic factor and promotes ovarian carcinoma cell proliferation in ovarian cancer

Tianren Li, Hui Xue, Yi Guo, Kejun Guo
Article Number: 3
Published online on: 16 October 2025

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Platelet‑circulating tumor cell crosstalk: A pivotal target in cancer diagnosis and therapy (Review)

Lifang Zhang, Ye Yuan, Yan Deng, Lin Wang, Fenghua Chen
Article Number: 2
Published online on: 15 October 2025

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Expression of Concern Open Access

[Expression of Concern] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 1
Published online on: 14 October 2025

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Journal Cover
February-2026 Volume 55 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Alternative splicing in cancer drug resistance: Mechanisms and therapeutic prospects (Review)

Wenpu Zhu, Zikun Wu, Chai Luv, Banghe Bao, Weijie Zhao, Guanglong Chen, Hang Yang, Huihan Ai, Faqiang Liu, Zhi Li
Article Number: 31
Published online on: 05 December 2025

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Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells

Liangliang Jin, Li Wei, Junrui Hua, Rong Zhang, Jiaxin Chen, Jinpeng He, Yanli Yang
Article Number: 30
Published online on: 04 December 2025

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Beyond eradication: Therapeutic reprogramming strategies for cancer normalization (Review)

Aliasgar Shahiwala
Article Number: 29
Published online on: 04 December 2025

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Article Open Access

Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy

Rui Zheng, Yusi Liu, Sen Zhou, Guimei Liu, Xiaobin Liu, Yiyuan Yang, Yufu Zhang
Article Number: 28
Published online on: 04 December 2025

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Retraction Open Access

[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Article Number: 27
Published online on: 04 December 2025

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Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma

Yuto Kitano, Tomoharu Miyashita, Takeo Shimasaki, Isamu Makino, Yoshio Endo, Yasuhiko Yamamoto, Noriyuki Inaki, Shintaro Yagi
Article Number: 26
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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