Journal Articles

Open Access

Overexpression of Opa interacting protein 5 increases the progression of liver cancer via BMPR2/JUN/CHEK1/RAC1 dysregulation

Yuwen Li, Fei Xiao, Wenting Li, Pingping Hu, Ruirui Xu, Jun Li, Guimei Li, Chuanlong Zhu

Pages: 2075-2088 Published online on: 11 February 2019
Open Access

The underlying molecular mechanism and potential drugs for treatment in papillary renal cell carcinoma: A study based on TCGA and Cmap datasets

Jin‑Shu Pang, Zhe‑Kun Li, Peng Lin, Xiao‑Dong Wang, Gang Chen, Hai‑Biao Yan, Sheng‑Hua Li

Pages: 2089-2102 Published online on: 14 February 2019
Open Access

TSPAN1 upregulates MMP2 to promote pancreatic cancer cell migration and invasion via PLCγ

Xiaobo Zhang, Gang Shi, Feng Gao, Peng Liu, Huaitao Wang, Xiaodong Tan

Pages: 2117-2125 Published online on: 30 January 2019
Open Access

Adipose‑derived mesenchymal stem cells exhibit tumor tropism and promote tumorsphere formation of breast cancer cells

Yanqing Chen, Yunfan He, Xuecen Wang, Feng Lu, Jianhua Gao

Pages: 2126-2136 Published online on: 15 February 2019
Open Access

Overexpression of BHLHE41, correlated with DNA hypomethylation in 3'UTR region, promotes the growth of human clear cell renal cell carcinoma

Zhouji Shen, Ling Zhu, Chao Zhang, Xiaobo Cui, Jun Lu

Pages: 2137-2147 Published online on: 07 February 2019
Open Access

IL22 furthers malignant transformation of rat mesenchymal stem cells, possibly in association with IL22RA1/STAT3 signaling

Xiangrong Cui, Xuan Jing, Qin Yi, Zhongping Xiang, Jie Tian, Bin Tan, Jing Zhu

Pages: 2148-2158 Published online on: 11 February 2019
Open Access

Polo‑like kinase 4 promotes tumorigenesis and induces resistance to radiotherapy in glioblastoma

Jia Wang, Jie Zuo, Maode Wang, Xudong Ma, Ke Gao, Xiaobin Bai, Ning Wang, Wanfu Xie, Hao Liu

Pages: 2159-2167 Published online on: 14 February 2019
Open Access

Analysis of gene co‑expression network reveals prognostic significance of CNFN in patients with head and neck cancer

Baoling Liu, Guanhong Huang, Hongming Zhu, Zhaoming Ma, Xiaokang Tian, Li Yin, Xingya Gao, Xia He

Pages: 2168-2180 Published online on: 18 February 2019
Open Access

Chlorophyllin e6‑mediated photodynamic therapy inhibits proliferation and induces apoptosis in human bladder cancer cells

Zhiyuan Zhuo, Zhenyu Song, Zhe Ma, Yuanfang Zhang, Guoxiong Xu, Gang Chen

Pages: 2181-2193 Published online on: 14 February 2019
Open Access

In silico analysis identified miRNA‑based therapeutic agents against glioblastoma multiforme

Dan‑Dan Xiong, Wen‑Qing Xu, Rong‑Quan He, Yi‑Wu Dang, Gang Chen, Dian‑Zhong Luo

Pages: 2194-2208 Published online on: 19 February 2019
Open Access

Reconstruction and analysis of circRNA‑miRNA‑mRNA network in the pathology of cervical cancer

Yuexiong Yi, Yanyan Liu, Wanrong Wu, Kejia Wu, Wei Zhang

Pages: 2209-2225 Published online on: 21 February 2019
Open Access

miR‑146a‑5p targets TCSF and influences cell growth and apoptosis to repress NSCLC progression

Wen‑Ting Huang, Rong‑Quan He, Xiao‑Jiao Li, Jie Ma, Zhi‑Gang Peng, Jin‑Cai Zhong, Xiao‑Hua Hu, Gang Chen

Pages: 2226-2240 Published online on: 25 February 2019
Open Access

Novel drug candidate for the treatment of several soft‑tissue sarcoma histologic subtypes: A computational method using survival‑associated gene signatures for drug repurposing

Xia Yang, Wen‑Ting Huang, Hua‑Yu Wu, Rong‑Quan He, Jie Ma, An‑Gui Liu, Gang Chen

Pages: 2241-2253 Published online on: 26 February 2019

Prostaglandin D2 expression is prognostic in high‑grade serous ovarian cancer

Mariana Rezende Alves, Nayra Soares Do Amaral, Fabio Albuquerque Marchi, Felipe Ilelis De Barros Silva, Alexandre André Balieiro Anastácio Da Costa, Kátia Cândido Carvalho, Glauco Baiocchi, Fernando Augusto Soares, Louise De Brot, Rafael Malagoli Rocha

Pages: 2254-2264 Published online on: 28 January 2019

Expression of protein disulfide isomerase A3 and its clinicopathological association in gastric cancer

Tomohiro Shimoda, Ryuichi Wada, Shoko Kure, Kousuke Ishino, Mitsuhiro Kudo, Ryuji Ohashi, Itsuo Fujita, Eiji Uchida, Hiroshi Yoshida, Zenya Naito

Pages: 2265-2272 Published online on: 05 February 2019

CADM2 inhibits human glioma proliferation, migration and invasion

Nan Liu, Chen Yang, Wansheng Bai, Zhen Wang, Xin Wang, Mark Johnson, Wenshi Wang, Pengxing Zhang, Hongwei Yang, Hui Liu, Yingduan Cheng, Yanyang Tu

Pages: 2273-2280 Published online on: 13 February 2019

ARHGAP6 regulates the proliferation, migration and invasion of lung cancer cells

Yongkai Wu, Ming Xu, Rong He, Ke Xu, Yegang Ma

Pages: 2281-2888 Published online on: 25 February 2019

Establishment and characterization of novel human oral squamous cell carcinoma cell lines from advanced‑stage tumors of buccal mucosa

Nilesh P. Gawas, Sushant S. Navarange, Gopal L. Chovatiya, Pankaj Chaturvedi, Sanjeev K. Waghmare

Pages: 2289-2298 Published online on: 07 February 2019

Expression and prognostic significance of insulin‑like growth factor-2 receptor in human hepatocellular carcinoma and the influence of transarterial chemoembolization

Anja Lautem, Frank Simon, Maria Hoppe‑Lotichius, Jens Mittler, Johanna  Vollmar, Arno Schad, Christoph Düber, Peter Robert Galle, Gerd Otto, Tim Zimmermann, Hauke Lang

Pages: 2299-2310 Published online on: 01 February 2019

Icariin suppresses cell cycle transition and cell migration in ovarian cancer cells

Pengzhen Wang, Jinli Zhang, Xifeng Xiong, Wei Yuan, Shengnan Qin, Wenjuan Cao, Libing Dai, Fuqin Xie, Aiguo Li, Zhihe Liu

Pages: 2321-2328 Published online on: 28 January 2019

SPAG9/MKK3/p38 axis is a novel therapeutic target for liver cancer

Shudi Luo, Biqiong Ren, Guoying Zou, Junlong Liu, Wei Chen, Yiran Huang, Xing Chen, Yin Fu

Pages: 2329-2336 Published online on: 30 January 2019

SHIP1 inhibits cell growth, migration, and invasion in non‑small cell lung cancer through the PI3K/AKT pathway

Qiaofen Fu, Yuhui Huang, Chunlei Ge, Zhen Li, Hui Tian, Qiaolin Li, Hongshuai Li, Ruilei Li, Xingyu Tao, Yuanbo Xue, Ying Wang, Guanqin Yang, Weiyi Fang, Xin Song

Pages: 2337-2350 Published online on: 30 January 2019

Promoter hypermethylation of SOX11 promotes the progression of cervical cancer in vitro and in vivo

Xiaofang Li, Xiaoling Wu, Yun Li, Yumeng Cui, Run Tian, Namita Singh, Muyang Ding, Yang Yang, Yan'e Gao

Pages: 2351-2360 Published online on: 01 February 2019

MicroRNA‑144 suppresses aggressive phenotypes of tumor cells by targeting ANO1 in colorectal cancer

Yasu Jiang, Yunhui Cai, Weiwei Shao, Feng Li, Zongyu Guan, Yi Zhou, Chong Tang, Shichun Feng

Pages: 2361-2370 Published online on: 21 February 2019

Anti‑tissue factor antibody‑mediated immuno‑SPECT imaging of tissue factor expression in mouse models of pancreatic cancer

Aya Sugyo, Winn Aung, Atsushi B. Tsuji, Hitomi Sudo, Hiroki Takashima, Masahiro Yasunaga, Yasuhiro Matsumura, Tsuneo Saga, Tatsuya Higashi

Pages: 2371-2378 Published online on: 14 February 2019

The role of GDF15 in bone metastasis of lung adenocarcinoma cells

Lian Duan, Hai‑Lin Pang, Wen‑Jun Chen, Wei‑Wei Shen, Pei‑Pei Cao, Shu‑Mei Wang, Li‑Li Liu, He‑Long Zhang

Pages: 2379-2388 Published online on: 21 February 2019

LYPD8 regulates the proliferation and migration of colorectal cancer cells through inhibiting the secretion of IL‑6 and TNF‑α

Jianbin Xu, Jun Qian, Wei Zhang, Engeng Chen, Guolin Zhang, Gaoyang Cao, Fei Wang, Xuning Shen, Wei Zhou, Zhangfa Song

Pages: 2389-2395 Published online on: 26 February 2019

Low expression of AIM2 combined with high expression of p‑STAT3 is associated with poor prognosis in hypopharyngeal squamous cell carcinoma

Zhen Li, Xinli Shi, Hui Li, Weiyi Wang, Xiaoming Li

Pages: 2396-2408 Published online on: 25 February 2019

Bufotalin induces cell cycle arrest and cell apoptosis in human malignant melanoma A375 cells

Zhaohai Pan, Chuanjun Qu, Ying Chen, Xiaoyu Chen, Xiaona Liu, Wenjin Hao, Wenjuan Xu, Lei Ye, Peng Lu, Defang Li, Qiusheng Zheng

Pages: 2409-2417 Published online on: 26 February 2019

TNF‑α inhibits xenograft tumor formation by A549 lung cancer cells in nude mice via the HIF‑1α/VASP signaling pathway

Wen Liu, Xiang Chen, Yanqi He, Yihao Tian, Liu Xu, Yanbin Ma, Pengchao Hu, Ke Su, Zhenyu Luo, Lei Wei, Jingwei Zhang

Pages: 2418-2430 Published online on: 21 February 2019

Upregulation and hypomethylation of lncRNA AFAP1‑AS1 predicts a poor prognosis and promotes the migration and invasion of cervical cancer

Hao Bo, Liqing Fan, Zhaojian Gong, Zhizhong Liu, Lei Shi, Can Guo, Xiayu Li, Qianjin Liao, Wenling Zhang, Ming Zhou, Bo Xiang, Xiaoling Li, Guiyuan Li, Wei Xiong, Zhaoyang Zeng, Ke Cao, Shanshan Zhang, Fang Xiong

Pages: 2431-2439 Published online on: 21 February 2019

Expression profiles analysis identifies the values of carcinogenesis and the prognostic prediction of three genes in adrenocortical carcinoma

Zhipeng Gao, Xiaojun Man, Zhenhua Li, Jianbin Bi, Xiankui Liu, Zeliang Li, Yuyan Zhu, Zhe Zhang, Chuize Kong

Pages: 2440-2452 Published online on: 19 February 2019

Deoxypodophyllotoxin inhibits cell viability and invasion by blocking the PI3K/Akt signaling pathway in human glioblastoma cells

Wei Wang, Wei Gao, Luyang Zhang, Dongyong Zhang, Zilong Zhao, Yijun Bao

Pages: 2453-2463 Published online on: 14 February 2019

Myristoylated alanine rich protein kinase C substrate is a potential cancer prognostic factor that regulates cell migration and invasion in glioblastoma

Wei Xiang, Tao Peng, Yang Ming, Shenjie Li, Ke Wang, Haorun Wang, Ligang Chen, Jie Zhou

Pages: 2464-2470 Published online on: 13 February 2019

CDCA3 is a potential prognostic marker that promotes cell proliferation in gastric cancer

Yan Zhang, Wei Yin, Wei Cao, Peisheng Chen, Longjun Bian, Qingfeng Ni

Pages: 2471-2481 Published online on: 12 February 2019

Multikinase inhibitor motesanib enhances the antitumor effect of cisplatin in cisplatin‑resistant human bladder cancer cells via apoptosis and the PI3K/Akt pathway

Jin‑Nyoung Ho, Seok‑Soo Byun, Sang Eun Lee, Je‑In Youn, Sangchul Lee

Pages: 2482-2490 Published online on: 11 February 2019

Association of CCL2, CCR2 and CCL5 genetic polymorphisms with the development and progression of benign prostatic hyperplasia

Yangyang Pang, Haoran Li, Yuwen Gong, Suoshi Jing, Cheng Peng, Wei Liu, Youli Zhao, Hanzhang Wang, Dharam Kaushik, Ronald Rodriguez, Zhiping Wang

Pages: 2491-2501 Published online on: 06 February 2019

Isoliquiritigenin inhibits the proliferation, apoptosis and migration of osteosarcoma cells

Chengjun Li, Xing Zhou, Chang Sun, Xiaozhou Liu, Xin Shi, Sujia Wu

Pages: 2502-2510 Published online on: 04 February 2019

MYC promotes the development of papillary thyroid carcinoma by inhibiting the expression of lncRNA PAX8‑AS1:28

Yi Zhang, Feilei Li, Jun Chen

Pages: 2511-2517 Published online on: 01 February 2019

CHAF1B promotes proliferation and reduces apoptosis in 95‑D lung cancer cells and predicts a poor prognosis in non‑small cell lung cancer

Yan Duan, Tanzhen Liu, Shengwen Li, Mingguang Huang, Xiaoyu Li, Hui Zhao, Jianqiang Li

Pages: 2518-2528 Published online on: 01 February 2019

Monocarboxylate transporter 1 is an independent prognostic factor in esophageal squamous cell carcinoma

Xue Chen, Xuan Chen, Fang Liu, Qianqian Yuan, Kaixian Zhang, Wei Zhou, Shanghui Guan, Yuanyuan Wang, Si Mi, Yufeng Cheng

Pages: 2529-2539 Published online on: 31 January 2019

MELK inhibition targets cancer stem cells through downregulation of SOX2 expression in head and neck cancer cells

Lili Ren, Boya Deng, Vassiliki Saloura, Jae‑Hyun Park, Yusuke Nakamura

Pages: 2540-2548 Published online on: 30 January 2019

Autophagy and apoptotic machinery caused by Polygonum cuspidatum extract in cisplatin‑resistant human oral cancer CAR cells

Yin‑Lai Wang, Chi‑Ting Horng, Min‑Tsang Hsieh, Hung‑Che Chen, Yu‑Syuan Huang, Jai‑Sing Yang, Guo‑Kai Wang, Jo‑Hua Chiang, Hul‑Han Chen, Chi‑Cheng Lu, Fu‑An Chen

Pages: 2549-2557 Published online on: 28 January 2019

Organic anion‑transporting polypeptides contribute to the uptake of curcumin and its main metabolites by human breast cancer cells: Impact on antitumor activity

Nattharat Jaerapong, Qurratul Ain Jamil, Juliane Riha, Daniela Milovanovic, Georg Krupitza, Bruno Stieger, Kanokwan Jarukomjorn, Walter Jäger

Pages: 2558-2566 Published online on: 14 February 2019

Tripartite motif‑containing 11 regulates the proliferation and apoptosis of breast cancer cells

Xianping Dai, Feng Geng, Mengshun Li, Ming Liu

Pages: 2567-2574 Published online on: 14 February 2019

NSPc1 polycomb protein complex binds and cross‑talks to lncRNAs in glioma H4 cells

Yuliang Wang, Zhikong Liang, Hui Li, Jinglong Tao, Yi Sun, Yanhua Gong

Pages: 2575-2584 Published online on: 05 February 2019

Cellular and radiobiological effects of carbonic anhydrase IX in human breast cancer cells

Antje Güttler, Katharina Theuerkorn, Anne Riemann, Henri Wichmann, Jacqueline Kessler, Oliver Thews, Matthias Bache, Dirk Vordermark

Pages: 2585-2594 Published online on: 05 February 2019

Inhibition of apoptosis by miR‑122‑5p in α‑fetoprotein‑producing gastric cancer

Suguru Maruyama, Shinji Furuya, Kensuke Shiraishi, Hiroki Shimizu, Ryo Saito, Hidenori Akaike, Naohiro Hosomura, Yoshihiko Kawaguchi, Hidetake Amemiya, Hiromichi Kawaida, Makoto Sudo, Shingo Inoue, Hiroshi Kono, Daisuke Ichikawa

Pages: 2595-2600 Published online on: 20 February 2019
Open Access

[Erratum] OBP‑801, a novel histone deacetylase inhibitor, induces M‑phase arrest and apoptosis in rhabdomyosarcoma cells

Chihiro Tomoyasu, Ken Kikuchi, Daisuke Kaneda, Shigeki Yagyu, Mitsuru Miyachi, Kunihiko Tsuchiya, Tomoko Iehara, Toshiyuki Sakai, Hajime Hosoi

Pages: 2601-2601 Published online on: 01 February 2019
Journal Cover

April-2019
Volume 41 Issue 4

Print ISSN: 1021-335X
Online ISSN: 1791-2431

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