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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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International Journal of Molecular Medicine

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
June 2012 Volume 29 Issue 6

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Journal Metrics

Impact Factor: 8.5

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review

Functional MRI using robotic MRI compatible devices for monitoring rehabilitation from chronic stroke in the molecular medicine era (Review)

Loukas G. Astrakas, Syed Hassan Naqvi, Babak Kateb, A. Aria Tzika
Pages: 963-973
Published online on: 15 March 2012

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Article

Resveratrol: Antioxidant activity and induction of fetal hemoglobin in erythroid cells from normal donors and β-thalassemia patients

Eitan Fibach, Eugenia Prus, Nicoletta Bianchi, Cristina Zuccato, Giulia Breveglieri, Francesca Salvatori, Alessia Finotti, Michele Lipucci di Paola, Eleonora Brognara, Ilaria Lampronti, Monica Borgatti, Roberto Gambari
Pages: 974-982
Published online on: 28 February 2012

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Evaluation of circulating CD4+CD25+ and liver-infiltrating Foxp3+ cells in HCV-associated liver disease

Alfredo Amoroso, Fabio D'Amico, Maria Consolo, Evangelia Skarmoutsou, Sergio Neri, Umberto Dianzani, Demetrios A. Spandidos, Maria Clorinda Mazzarino
Pages: 983-988
Published online on: 22 March 2012

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Article

Na+/H+-exchanger-1 inhibition counteracts diabetic cataract formation and retinal oxidative-nitrative stress and apoptosis

Sergey Lupachyk, Roman Stavniichuk, Julia I. Komissarenko, Viktor R. Drel, Alexander A. Obrosov, Azza B. El-Remessy , Pal Pacher, Irina G. Obrosova
Pages: 989-998
Published online on: 07 March 2012

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Article

Emodin inhibits tumor necrosis factor-α-induced migration and inflammatory responses in rat aortic smooth muscle cells

Liang Meng, Dongming Yan, Weidong Xu, Jian Ma, Bin Chen, Hong  Feng
Pages: 999-1006
Published online on: 15 March 2012

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Article

Effects of bisphosphonates on osteoclastogenesis in RAW264.7 cells

Keigo Abe, Yoshitaka Yoshimura, Yoshiaki Deyama, Takashi Kikuiri , Tomokazu Hasegawa, Kanchu Tei, Hisashi Shinoda, Kuniaki Suzuki, Yoshimasa Kitagawa
Pages: 1007-1015
Published online on: 23 March 2012

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Article

Μolecular impact of bone morphogenetic protein 7, on lung cancer cells and its clinical significance Corrigendum in /10.3892/ijmm.2025.5585

Yinan Liu, Jinfeng Chen, Yue Yang, Lijian Zhang, Wen G. Jiang
Pages: 1016-1024
Published online on: 23 March 2012

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Article

Apoptosis induced by pneumolysin in human endothelial cells involves mitogen-activated protein kinase phosphorylation

Aie Zhou, Hong Wang, Kai Lan, Xuemei Zhang, Wenchun Xu, Yibing Yin, Dairong Li, Jun Yuan, Yujuan He
Pages: 1025-1030
Published online on: 22 March 2012

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Article

Spatiotemporal behavior of nuclear cyclophilin B indicates a role in RNA transcription

Birger Dieriks, Patrick Van Oostveldt
Pages: 1031-1038
Published online on: 13 March 2012

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Article

Protein kinase CK2 mediates peroxynitrite-induced heme oxygenase-1 expression in articular chondrocytes

Kang Mi Kim, Ju Dong Song, Hun Taeg Chung, Young Chul Park
Pages: 1039-1044
Published online on: 23 March 2012

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Article

Zanthoxylum avicennae extracts inhibit cell proliferation through protein phosphatase 2A activation in HA22T human hepatocellular carcinoma cells in vitro and in vivo

Tran Duc Dung, Hsien-Cheh Chang, Truong Viet Binh, Maw-Rong Lee, Chang-Hai Tsai, Fuu-Jen Tsai, Wei-Wen Kuo, Li-Mien Chen, Chih-Yang Huang
Pages: 1045-1052
Published online on: 13 March 2012

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Article

Potent inhibitory effect of Foeniculum vulgare Miller extract on osteoclast differentiation and ovariectomy-induced bone loss

Tae-Ho Kim, Hyun-Ju Kim, Sang-Han Lee, Shin-Yoon Kim
Pages: 1053-1059
Published online on: 23 March 2012

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Article

Dicer 1, ribonuclease type III modulates a reprogramming effect in colorectal cancer cells

Dyah Laksmi Dewi, Hideshi Ishii, Naotsugu Haraguchi, Shimpei Nishikawa, Yoshihiro Kano, Takahito Fukusumi, Miyuki Ozaki, Toshiyuki Saito, Daisuke Sakai, Taroh Satoh, Yuichiro Doki, Masaki Mori
Pages: 1060-1064
Published online on: 19 March 2012

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Article

A novel GATA6 mutation associated with congenital ventricular septal defect

Gui-Fen Zheng, Dong Wei, Hong Zhao, Ning Zhou, Yi-Qing Yang, Xing-Yuan Liu
Pages: 1065-1071
Published online on: 07 March 2012

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Article

Pretreatment with Mycobacterium avium-derived lipids attenuates the response of murine macrophages to components of Mycobacterium tuberculosis

Daqing Yang, Yuan Liu, Yiguo Chen, Delong Jiao, Xiaorui Hou, Lei Wang, Ning Fu
Pages: 1072-1082
Published online on: 07 March 2012

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Article

Osteogenic response of mesenchymal stem cells to continuous mechanical strain is dependent on ERK1/2-Runx2 signaling

Peng Zhang, Yuqiong Wu, Zonglai Jiang, Lingyong Jiang, Bing Fang
Pages: 1083-1089
Published online on: 08 March 2012

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Astragaloside II induces osteogenic activities of osteoblasts through the bone morphogenetic protein-2/MAPK and Smad1/5/8 pathways

Xiang-He Kong, Yin-Bo Niu, Xiao-Mei Song, Dong-Dong Zhao, Juan Wang, Xiang-Long Wu, Rong Zhang, Qi-Bing Mei
Pages: 1090-1098
Published online on: 15 March 2012

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Article

Proteomic analysis of oxidative modification in endothelial colony-forming cells treated by hydrogen peroxide

Jun Wei, Ying Liu, Ming Chang, Chong-Ling Sun, Da-Wei Li, Zhi-Qiang Liu, Lin-Sen Hu
Pages: 1099-1105
Published online on: 19 March 2012

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Article

IL-6 induction of hepatocyte proliferation through the Tmub1-regulated gene pathway

Menggang Liu, Hongming Liu, Xiaofeng Wang, Ping Chen, Hongxu Chen
Pages: 1106-1112
Published online on: 15 March 2012

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Article

CCM2 gene polymorphisms in Italian sporadic patients with cerebral cavernous malformation: A case-control study

Rosalia D'Angelo, Concetta Scimone, Carmela Rinaldi, Giuseppe Trimarchi, Domenico Italiano, Placido Bramanti, Aldo Amato, Antonina Sidoti
Pages: 1113-1120
Published online on: 28 February 2012

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Perturbation of glycerol metabolism in hepatocytes from n3-PUFA-depleted rats

Laurence Portois, Ying Zhang, Laurence Ladrière, Jason Perret, Karim Louchami, Nathalie Gaspard, Emeline Hupkens, Nargis Bolaky, Valérie Delforge, Renaud Beauwens, Willy J. Malaisse, Abdullah Sener, Yvon A. Carpentier, Christine Delporte
Pages: 1121-1126
Published online on: 16 March 2012

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Article

Estrogen receptor β transcript variants associate with oncogene expression in endometrial cancer

Julia Häring, Maciej Skrzypczak, Anette Stegerer, Claus Lattrich, Florian Weber, Regina Görse, Olaf Ortmann, Oliver Treeck
Pages: 1127-1136
Published online on: 28 February 2012

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Article

Anti-atherogenic activity of wild grape (Vitis thunbergii) extract antagonizing smooth muscle cell proliferation and migration promoted by neighboring macrophages

Sang-Wook Kang, Min Soo Kim, Hyun-Sung Kim, Yong-Jin Lee, Young-Hee Kang
Pages: 1137-1145
Published online on: 07 March 2012

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Article

7,8-Dihydroxyflavone exhibits anti-inflammatory properties by downregulating the NF-κB and MAPK signaling pathways in lipopolysaccharide-treated RAW264.7 cells

Hye Young Park, Gi-Young Kim, Jin Won Hyun, Hye   Jin Hwang, Nam  Deuk Kim, Byung-Woo  Kim, Yung Hyun Choi
Pages: 1146-1152
Published online on: 13 March 2012

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Article

Adenovirally delivered IFN-β exerts antitumor effects through transient T-lymphocyte depletion and Ag-specific T-cell proliferation

Sang-Seok Oh, Chaerin Moon, Dong-Hyeok Kim, Hyunkeun  Song, Saegwang  Park, Yangxin Fu, Kwang Dong Kim
Pages: 1153-1157
Published online on: 13 March 2012

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Article

Characterization of hepatocellular carcinoma cell lines based on cell adhesion molecules

Cheol Woong Jung, Tae-Jin Song, Kun-Ok Lee, Sae Byeol Choi, Wan Bae Kim, Sung Ock Suh, Young Chul Kim, Sang Yong Choi
Pages: 1158-1164
Published online on: 23 March 2012

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Journal Cover
October-2026 Volume 58 Issue 4

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Journal Metrics

Impact Factor: 8.5

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Role of adipocytes and their derived extracellular vesicles in the progression, diagnosis and treatment of liver diseases (Review)

Kangrong Li, Muhammad Zubair, Yongmin Yan, Jiahao Xu
Article Number: 293
Published online on: 20 August 2026

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Correction Open Access

[Corrigendum] EBM84 attenuates airway inflammation and mucus hypersecretion in an ovalbumin‑induced murine model of asthma

In Sik Shin, Mee Young Lee, Woo Young Jeon, Na Ra Shin, Chang Seob Seo, Hyekyung Ha
Article Number: 292
Published online on: 20 August 2026

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Decoding fibroblast activation: Transcriptional networks in hepatic stellate cells and across fibrotic organs (Review)

Denita Charoenthanakitkul, Chaiyaboot Ariyachet
Article Number: 291
Published online on: 20 August 2026

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Inflammatory bowel disease treatment: Mechanisms to clinical translation (Review)

Siqi Tang, Guoyou Gou, Youjia Liu, Fang Wang, Feihong Shu, Ya Deng, Ting Zhang, Jingyu Xu, Rui Xie
Article Number: 290
Published online on: 18 August 2026

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Redox biology in PCOS: Biomarkers, mechanistic networks, and targeted interventions (Review)

Yuena Qiu, Xiaojing Guo, Jie An
Article Number: 289
Published online on: 18 August 2026

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Review Open Access

Glucose metabolism in osteoporosis: A potential therapeutic target (Review)

Shengyao Peng, Zhuo Yao, Junzhe Guo, Chi Zhang, Keda Yang, Lin Tao
Article Number: 288
Published online on: 17 August 2026

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Retraction Open Access

[Retracted] Engulfment of platelets delays endothelial cell aging via girdin and its phosphorylation

Yong Lan, Yongjun Li, Dajun Li, Peng Li, Jiyang Wang, Yongpeng Diao, Guodong Ye, Yangfang Li
Article Number: 287
Published online on: 17 August 2026

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Article Open Access

α‑Cyperone targets the PAK1‑JNK/NF‑κB axis to modulate dendritic cells maturation and Th2/Th9 differentiation in an asthma model

Hang Hu, Xing Wang, Linlin Guo, Ziling Zeng, Hongmei Tang, Yun Zhang, Jiayao Duan, Kaijin Wang
Article Number: 286
Published online on: 14 August 2026

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Article Open Access

Early high‑frequency spinal cord stimulation modulates the ROS/p38 MAPK/NF‑κB and CXCL10/CXCR3 pathways to alleviate neuropathic pain and promote spinal cord injury repair

Sitong Su, Tao Liu, Honghui Lei, Yang Yu, Caizhi Ma, Xinglang Wang, Haoyuan Chen, Zebin Huang, Meiling Cheng, Tongtong Qian, Fangyong Wang
Article Number: 285
Published online on: 13 August 2026

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Review Open Access

Shared mechanisms of musculoskeletal dysfunction in type 2 diabetes mellitus: Insights into future therapeutic directions (Review)

Zhenhong He, Hanyu Li, Yuhan Luo, Yingying Yu, Siyu Li, Tao Zhang, Dingsu Bao
Article Number: 284
Published online on: 12 August 2026

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Expression of Concern Open Access

[Expression of Concern] Exogenous spermine attenuates diabetic kidney injury in rats by inhibiting AMPK/mTOR signaling pathway

Xinying Zhang, Li Zhang, Zhe Chen, Siwei Li, Bingbing Che, Ningning Wang, Junting Chen, Changqing Xu, Can Wei
Article Number: 283
Published online on: 12 August 2026

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Article Open Access

G protein‑coupled receptor kinase 4 governs early kidney development via STAT3 and Nhe3a

Linh Anna Trúc Vu, Julian Gerhards, Lars D. Maerz, Martin D. Burkhalter, Melanie Philipp
Article Number: 282
Published online on: 11 August 2026

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Retraction Open Access

[Retracted] Resistant starch prevents tumorigenesis of dimethylhydrazine‑induced colon tumors via regulation of an ER stress‑mediated mitochondrial apoptosis pathway  

Qiuyu Wang, Peng Wang, Zhigang Xiao
Article Number: 281
Published online on: 10 August 2026

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Review Open Access

XBP1 signaling from tumor metabolic stress to myeloid driven immunotherapy resistance (Review)

Ziwei Chen, Jiaqi Wu, Wenxi Liu, Jie Tan, Xiaochun Peng, Yanhua Zhang, Gai Liang
Article Number: 280
Published online on: 05 August 2026

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Review Open Access

Decoding miRNA‑146a: Mechanisms of action in cardiovascular diseases and endocrine metabolic disorders (Review)

Xiu Yang, Pengcheng Li, Hao Zhao
Article Number: 279
Published online on: 05 August 2026

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Review Open Access

Contribution of p38 MAPK in liver fibrosis: An overview of mechanisms, signaling pathways, and therapeutic targets (Review)

Xueqin Yang, Huarong Li, Hao Ye, Ting Wu, Fangyun Xu, Chao Hu, Chunlei Yu, Pian Ye
Article Number: 278
Published online on: 05 August 2026

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Correction Open Access

[Corrigendum] Peroxisome proliferator‑activated receptor α regulates acesulfame‑K‑induced NAFLD via hepatic PLCβ: Foe and friend

Peng-Yao Lin, Jia-Rong Xie, Tian-Chen Qian, Shi-Song Wang, Si-Yi Yu, Wen-Bo Shi, Ying Wang, Lu-Ze Cen, Qing-Jing Zhu, Yi-Yang Zheng, Hui Gao, Rong Fang, Zhao-Xia Xia, Ai-Ming Liu, Lei Xu
Article Number: 277
Published online on: 05 August 2026

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Review Open Access

Multi‑omics insights into uveitis: From mechanisms to precision medicine (Review)

Chengzhi Liu, Qiong Wu, Mingzhen Yuan, Mingyue Liu, Xinyu Wang, Jiaqi Shen, Xusheng Cao
Article Number: 276
Published online on: 03 August 2026

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Retraction Open Access

[Retracted] Effects of miRNA‑455 on cardiac hypertrophy induced by pressure overload

Chuntao Wu, Shimin Dong, Yongjun Li
Article Number: 275
Published online on: 03 August 2026

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Article Open Access

Energy stress activates AMPK to suppress ferroptosis in neurodegenerative proteinopathies

Yuanyuan Yong, Yuxin Hu, Qian Feng, Xiaogang Zhou, Lu Yu, Dalian Qin, Jianing Mi, Jianming Wu, Jianxin Liu, Anguo Wu
Article Number: 274
Published online on: 31 July 2026

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Article Open Access

Brazilin attenuates methylglyoxal‑induced endothelial injury by enhancing eIF5A hypusination and inhibiting the AMPK/mTOR‑mediated autophagy/apoptosis axis in vitro and in vivo

Yu Liang, Jinxiang Chen, Haiyang Li, Junjing Xiong, Jingcan You, Liqun Wang, Jianbo Wu, Youkun Zheng, Mao Luo
Article Number: 273
Published online on: 30 July 2026

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Review Open Access

Post‑translational modifications in atherosclerosis: Roles, mechanisms and therapeutic potential (Review)

Xiaoxiang Xu, Fei Ma, Wei Yu
Article Number: 272
Published online on: 30 July 2026

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Review Open Access

Role of extracellular matrix in liver fibrosis regression and regeneration (Review)

Yuanzhi Zhou, Zeyuan Qiang, Yang Duan, Jiwei Huang, Haichuan Wang
Article Number: 271
Published online on: 29 July 2026

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Correction Open Access

[Corrigendum] Circulating microRNA profiles and the identification of miR‑593 and miR‑511 which directly target the PROP1 gene in children with combined pituitary hormone deficiency

Yanyan Hu, Qian Wang, Zengmin Wang, Fengxue Wang, Xiaobo Guo, Guimei Li
Article Number: 270
Published online on: 29 July 2026

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Review Open Access

Unveiling the role of spatial transcriptomics in the analysis of the tumor immune microenvironment (Review)

Jialin Jiang, Xinyu Tu, Yi Cao, Qun Yan, Buqing Sai, Jian Ma
Article Number: 269
Published online on: 28 July 2026

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Expression of Concern Open Access

[Expression of Concern] Luteolin protects mice from severe acute pancreatitis by exerting HO‑1‑mediated anti‑inflammatory and antioxidant effects

Jie Xiong, Kezhou Wang, Chunxiao Yuan, Rong Xing, Jianbo Ni, Guoyong Hu, Fengling Chen, Xingpeng Wang
Article Number: 268
Published online on: 27 July 2026

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Article Open Access

circRNA_013145‑miR‑185‑5p‑RhoA axis: A novel mechanism in the pathophysiology of diabetes‑induced erectile dysfunction

Wenhan Huang, Xin Lv, Jiahua Qian, Yihao Chen, Yuhe Si, Jingwei Wang, Jianxiong Ma
Article Number: 267
Published online on: 24 July 2026

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Review Open Access

Gut‑liver‑kidney axis: A systems biology framework for understanding and treating chronic kidney disease (Review)

Jinyi Hou, Yaotan Li, Shijia Lin, Qingqing Liu, Huijuan Zheng, Weijing Liu, Yaoxian Wang, Liang Peng, Zhen Wang
Article Number: 266
Published online on: 23 July 2026

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Review Open Access

Effects of cuproptosis and its application in inflammatory bowel disease (Review)

Li Chen, Francis Atim Akanyibah, Jing Guan, Bing Pei, Bo Wang, Fei Mao
Article Number: 265
Published online on: 23 July 2026

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Journal Cover
November-2026 Volume 58 Issue 5

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Journal Metrics

Impact Factor: 8.5

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Breaking the cycle of fibrosis: Ferroptosis as a therapeutic target (Review)

Xincheng Feng, Jue Zhang, Qinghong Ma, Chao Sun
Article Number: 298
Published online on: 27 August 2026

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Correction Open Access

[Corrigendum] Tumor‑targeting novel manganese complex induces ROS‑mediated apoptotic and autophagic cancer cell death

Jia Liu, Wenjie Guo, Jing Li, Xiang Li, Ji Geng, Qiuyun Chen, Jing Gao
Article Number: 297
Published online on: 26 August 2026

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Review Open Access

Advances in sirtuin research in lung diseases (Review)

Shuangyun Xi, Weijun Chen, Xiuli Li, Yudan Wang, Yong Ke
Article Number: 296
Published online on: 25 August 2026

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Article Open Access

lncRNA TUG1 mediates palmitic acid‑induced neuronal lipotoxic injury via the miR‑449a‑5p/caspase‑3 and Akt/GSK‑3β axes

Ya-Dong Wei, Peng-Quan Chen, Xin Zheng, Le-Qi Wu, Xin-Yi Wang, Xin-Ran Gao, Jin-Fang Ge
Article Number: 295
Published online on: 25 August 2026

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Retraction Open Access

[Retracted] Downregulation of LINC00707 promotes osteogenic differentiation of human bone marrow‑derived mesenchymal stem cells by regulating DKK1 via targeting miR‑103a‑3p

Jun Liu, Minfei Wu, Guang Feng, Rui Li, Yang Wang, Jianhang Jiao
Article Number: 294
Published online on: 24 August 2026

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