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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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International Journal of Molecular Medicine

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
2014-April Volume 33 Issue 4

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Journal Metrics

Impact Factor: 8.5

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Regulation of mRNA transport, localization and translation in the nervous system of mammals (Review)

Carlo Maria Di Liegro, Gabriella Schiera, Italia Di Liegro
Pages: 747-762
Published online on: 21 January 2014

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Review

The plasminogen activation system in periodontal tissue (Review)

Marzena Wyganowska-Świątkowska, Anna Surdacka, Ewa Skrzypczak-Jankun, Jerzy Jankun
Pages: 763-768
Published online on: 10 February 2014

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Review

S100 family signaling network and related proteins in pancreatic cancer (Review)

Yi-Fei Ji, Hua Huang, Feng Jiang, Run-Zhou Ni, Ming-Bing Xiao
Pages: 769-776
Published online on: 24 January 2014

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Review

Inflammation and peripheral arterial disease: The value of circulating biomarkers (Review)

Salvatore Santo Signorelli, Valerio Fiore, Grazia Malaponte
Pages: 777-783
Published online on: 13 February 2014

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Article Open Access

A clinicopathological review of 33 patients with vulvar melanoma identifies c-KIT as a prognostic marker

Viola A. Heinzelmann-Schwarz, Sheri Nixdorf, Mehrnaz Valadan, Monica Diczbalis, Jake Olivier, Geoff Otton, André Fedier, Neville F. Hacker, James P. Scurry
Pages: 784-794
Published online on: 14 February 2014

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Article Open Access

The (pro)renin receptor mediates constitutive PLZF-independent pro-proliferative effects which are inhibited by bafilomycin but not genistein

Sebastian Kirsch, Eva Schrezenmeier, Sabrina Klare, Daniela Zaade, Kerstin Seidel, Jennifer Schmitz, Sarah Bernhard, Dilyara Lauer, Mark Slack, Petra Goldin-Lang, Thomas Unger, Frank S. Zollmann, Heiko Funke-Kaiser
Pages: 795-808
Published online on: 14 January 2014

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Article Open Access

Role of endoplasmic reticulum stress in apoptosis of differentiated mouse podocytes induced by high glucose

Yanping Cao, Yongmei Hao, Hang Li, Qingjuan Liu, Feng Gao, Wei Liu, Huijun Duan
Pages: 809-816
Published online on: 03 February 2014

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Article Open Access

Mitochondrial DNA induces inflammation and increases TLR9/NF-κB expression in lung tissue Retraction in /10.3892/ijmm.2023.5231

Jian-Zheng Zhang, Zhi Liu, Jia Liu, Ji-Xin Ren, Tian-Sheng Sun
Pages: 817-824
Published online on: 10 February 2014

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Article Open Access

Effect of retinoic acid on the tight junctions of the retinal pigment epithelium-choroid complex of guinea pigs with lens-induced myopia in vivo

Sha Wang, Shuangzhen Liu, Junfeng Mao, Dan Wen
Pages: 825-832
Published online on: 10 February 2014

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Article Open Access

Priming with proangiogenic growth factors and endothelial progenitor cells improves revascularization in linear diabetic wounds

Maximilian Ackermann, Andreas M. Pabst, Jan P. Houdek, Thomas Ziebart, Moritz A. Konerding
Pages: 833-839
Published online on: 21 January 2014

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Article Open Access

Administration of erythropoietin exerts protective effects against glucocorticoid-induced osteonecrosis of the femoral head in rats

Sen Chen, Jianping Li, Hao Peng, Jianlin Zhou, Hongsong Fang
Pages: 840-848
Published online on: 05 February 2014

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Article Open Access

Endoplasmic reticulum stress activates transglutaminase 2 leading to protein aggregation

Jin-Haeng Lee, Jaeho Jeong, Eui Man Jeong, Sung-Yup Cho, Jeong Wook Kang, Jisun Lim, Jinbeom Heo, Hyunsook Kang, In-Gyu Kim, Dong-Myung Shin
Pages: 849-855
Published online on: 30 January 2014

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Article Open Access

SPARC silencing inhibits the growth of acute myeloid leukemia transformed from myelodysplastic syndrome via induction of cell cycle arrest and apoptosis

Qing Nian, Qing Xiao, Li Wang, Jing Luo, Li-Ping Chen, Ze-Song Yang, Lin Liu
Pages: 856-862
Published online on: 07 February 2014

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Article Open Access

Quercetin regulates the sestrin 2-AMPK-p38 MAPK signaling pathway and induces apoptosis by increasing the generation of intracellular ROS in a p53-independent manner

Guen Tae Kim, Se Hee Lee, Jong Il Kim, Young Min Kim
Pages: 863-869
Published online on: 13 February 2014

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Article

Berberine prevents nigrostriatal dopaminergic neuronal loss and suppresses hippocampal apoptosis in mice with Parkinson's disease

Mia Kim, Ki-Ho Cho, Mal-Soon Shin, Jae-Min Lee, Han-Sam Cho, Chang-Ju Kim, Dong-Hoon Shin, Hyeon Jeong Yang
Pages: 870-878
Published online on: 13 February 2014

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Article

Role of miR-200c/miR-141 in the regulation of epithelial-mesenchymal transition and migration in head and neck squamous cell carcinoma

Shunji Tamagawa, Levent Bekir Beder, Muneki Hotomi, Mehmet Gunduz, Kazuya Yata, Reidar Grenman, Noboru Yamanaka
Pages: 879-886
Published online on: 14 January 2014

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Article

Analysis of genes causing hypertension and stroke in spontaneously hypertensive rats: Gene expression profiles in the brain

Momoko Yoshida, Yuko Watanabe, Kyosuke Yamanishi, Akifumi Yamashita, Hideyuki Yamamoto, Daisuke Okuzaki, Kazunori Shimada, Hiroshi Nojima, Teruo Yasunaga, Haruki Okamura, Hisato Matsunaga, Hiromichi Yamanishi
Pages: 887-896
Published online on: 22 January 2014

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Article

DNA methylation patterns of steroid receptor genes ESR1, ESR2 and PGR in deep endometriosis compromising the rectum

Joana Ladeira Meyer, Daniela Zimbardi, Sérgio Podgaec, Renee Laufer Amorim, Maurício Simões Abrão, Cláudia Aparecida Rainho
Pages: 897-904
Published online on: 28 January 2014

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Article

Myosin light chain kinase regulates hearing in mice by influencing the F-actin cytoskeleton of outer hair cells and cochleae

Xia Yang, Jun-Guo Wang, Deng-Bin Ma, Xiao-Feng Ma, Guang-Jie Zhu, Han Zhou, Chen-Jie Yu, Xiao-Yun Qian, Xia Gao
Pages: 905-912
Published online on: 27 January 2014

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Article

Detection of CRB1 mutations in families with retinal dystrophy through phenotype-oriented mutational screening

Shiqiang Li, Tao Shen, Xueshan Xiao, Xiangming Guo, Qingjiong Zhang
Pages: 913-918
Published online on: 12 February 2014

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Article

Developmental endothelial locus-1 inhibits MIF production through suppression of NF-κB in macrophages

Seung-Hwan Lee, Dong-Young Kim, Yoon-Young Kang, Hyesoon Kim, Jungin Jang, Mi-Ni Lee, Goo Taeg Oh, Sang-Wook Kang, Eun Young Choi
Pages: 919-924
Published online on: 05 February 2014

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Article

Nicotine exerts neuroprotective effects against β-amyloid-induced neurotoxicity in SH-SY5Y cells through the Erk1/2-p38-JNK-dependent signaling pathway

Mao Qiang Xue, Xiao Xing Liu, Yan Ling Zhang, Feng Guang Gao
Pages: 925-933
Published online on: 24 January 2014

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Article

Troxerutin induces protective effects against ultraviolet B radiation through the alteration of microRNA expression in human HaCaT keratinocyte cells

Kwang Sik Lee, Hwa Jun Cha, Ghang Tai Lee, Kun Kook Lee, Jin Tae Hong, Kyu Joong Ahn, In-Sook An, Sungkwan An, Seunghee Bae
Pages: 934-942
Published online on: 03 February 2014

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Article

Corosolic acid induces apoptotic cell death in HCT116 human colon cancer cells through a caspase-dependent pathway

Bokyung Sung, Yong Jung Kang, Dong Hwan Kim, Seong Yeon Hwang, Yujin Lee, Minjeong Kim, Jeong-Hyun Yoon, Cheol Min Kim, Hae Young Chung, Nam Deuk Kim
Pages: 943-949
Published online on: 29 January 2014

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Article

MicroRNA-375 targets PDK1 in pancreatic carcinoma and suppresses cell growth through the Akt signaling pathway

Jian Zhou, Shiduo Song, Songbing He, Xinguo Zhu, Yi Zhang, Bin Yi, Bing Zhang, Gongzhao Qin, Dechun Li
Pages: 950-956
Published online on: 28 January 2014

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Article

Altered miRNA expression profiles are involved in the protective effects of troxerutin against ultraviolet B radiation in normal human dermal fibroblasts

Hwa Jun Cha, Kwang Sik Lee, Ghang Tai Lee, Kun Kook Lee, Jin Tae Hong, Sung Nae Lee, Hyun Hee Jang, Jae Ho Lee, In-Chul Park, Yu Ri Kim, Kyu Joong Ahn, Seung Bin Kwon, In-Sook An, Sungkwan An, Seunghee Bae
Pages: 957-963
Published online on: 07 February 2014

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Article

7,8-Dihydroxyflavone protects human keratinocytes against oxidative stress-induced cell damage via the ERK and PI3K/Akt-mediated Nrf2/HO-1 signaling pathways

Min Ju Ryu, Kyoung Ah Kang, Mei Jing Piao, Ki Cheon Kim, Jian Zheng, Cheng Wen Yao, Ji Won Cha, Ha Sook Chung, Sang Cheol Kim, Eunsun Jung, Deokhoon Park, Sungwook Chae, Jin Won Hyun
Pages: 964-970
Published online on: 04 February 2014

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Article

Effects of Alisma Decoction on lipid metabolism and inflammatory response are mediated through the activation of the LXRα pathway in macrophage-derived foam cells

Xiehua Xue, Tong Chen, Wei Wei, Xiaomao Zhou, Zhicheng Lin, Lidian Chen
Pages: 971-977
Published online on: 06 February 2014

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Article

Bangpungtongseong-san, a traditional herbal medicine, attenuates chronic asthmatic effects induced by repeated ovalbumin challenge

Mee-Young Lee, In-Sik Shin, Woo-Young Jeon, Nara Shin, Hyeun-Kyoo Shin
Pages: 978-986
Published online on: 10 February 2014

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Article

The prosurvival role of autophagy in resveratrol-induced cytotoxicity in GH3 cells

Xuexin Zhang, Wanhai Xu, Jun Su, Ming Chu, Hua Jin, Guofu Li, Chunlei Tan, Xin Wang, Chao Wang
Pages: 987-993
Published online on: 17 February 2014

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Article

Epigallocatechin-3-gallate inhibits TF and TNF-α expression induced by the anti-β2GPI/β2GPI complex in human THP-1 cells

Ting Wang, Hong Zhou, Hongxiang Xie, Yuan Mu, Ya Xu, Jingjing Liu, Xiaolei Zhang
Pages: 994-1002
Published online on: 27 January 2014

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Article

A canine model of Alzheimer's disease generated by overexpressing a mutated human amyloid precursor protein

Geun-Shik Lee, Yeon Woo Jeong, Joung Joo Kim, Sun Woo Park, Kyeong Hee Ko, Mina Kang, Yu Kyung Kim, Eui-Man Jung, Changjong Moon, Sang Hwan Hyun, Kyu‑Chan Hwang, Nam-Hyung Kim, Taeyoung Shin, Eui-Bae Jeung, Woo Suk Hwang
Pages: 1003-1012
Published online on: 28 January 2014

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Article

Resveratrol inhibits BMP-4-stimulated VEGF synthesis in osteoblasts: Suppression of S6 kinase

Akira Kondo, Takanobu Otsuka, Gen Kuroyanagi, Naohiro Yamamoto, Rie Matsushima-Nishiwaki, Jun Mizutani, Osamu Kozawa, Haruhiko Tokuda
Pages: 1013-1018
Published online on: 17 January 2014

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Article

Integrative genomic analyses of the histamine H1 receptor and its role in cancer prediction

Minghai Wang, Xiaolong Wei, Lianghui Shi, Bin Chen, Guohai Zhao, Haiwei Yang
Pages: 1019-1026
Published online on: 10 February 2014

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Article

7,8-Dihydroxyflavone attenuates the release of pro-inflammatory mediators and cytokines in lipopolysaccharide-stimulated BV2 microglial cells through the suppression of the NF-κB and MAPK signaling pathways

Hye Young Park, Cheol Park, Hye Jin Hwang, Byung Woo Kim, Gi-Young Kim, Cheol Min Kim, Nam Deuk Kim, Yung Hyun Choi
Pages: 1027-1034
Published online on: 10 February 2014

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Article

Proteomic comparison between abdominal and thoracic aortic aneurysms

Ken-Ichi Matsumoto, Kazumi Satoh, Tomoko Maniwa, Tetsuya Tanaka, Hideki Okunishi, Teiji Oda
Pages: 1035-1047
Published online on: 17 January 2014

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Correction Open Access

[Erratum] Anti-inflammatory effects of total alkaloids from Rubus aleaefolius Poir. on non-alcoholic fatty liver disease through regulation of the NF-κB pathway

Jinyan Zhao, Haiyin Zheng, Yan Liu, Jiumao Lin, Xiaoyong Zhong, Wei Xu, Zhenfeng Hong, Jun Peng
Pages: 1048-1048
Published online on: 17 January 2014

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Journal Cover
August-2026 Volume 58 Issue 2

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Journal Metrics

Impact Factor: 8.5

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Myokines in exercise‑mediated bone homeostasis: Molecular signaling mechanisms and therapeutic implications for bone disorders (Review)

Bin Tian, Xuesong Chen, Jiang Zheng, Xin Kang
Article Number: 231
Published online on: 24 June 2026

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Review Open Access

Neutrophil extracellular traps in thrombosis of hematologic malignancies: Underlying mechanisms and therapeutic opportunities (Review)

Kebing Lv, Zijie Ma, Qiuni Chen, Yang Su, Jingjing Ma, Chunling Wang, Liang Yu
Article Number: 230
Published online on: 23 June 2026

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Article Open Access

Recombinant myonectin ameliorates sepsis‑induced cardiomyopathy by alleviating mitochondrial dysfunction via the AdipoR1/AMPK pathway

Peipei Li, Rui Chen, Hanmo Zhang, Lihong Li, Huiling Luo, Beibei Du, Ping Yang
Article Number: 229
Published online on: 23 June 2026

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Review Open Access

MTA2: Decoding pathogenic mechanisms, clinical implications and therapeutic frontiers across disease landscapes (Review)

Hao Xie, Ling Chen, Jing Gou, Xuehong Long, Ya Yang, Hai Hu, Ping Wu, Qibing Yan, Yongkang Wu
Article Number: 228
Published online on: 22 June 2026

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Review Open Access

Mitochondria‑endoplasmic reticulum contact site nexus: Molecular integration, disease pathogenesis and therapeutic opportunities (Review)

Yi Liu, Xianda Che, Wei Wei, Chong Teng, Huimin Li
Article Number: 227
Published online on: 22 June 2026

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Review Open Access

Metabolic messengers from the gut to the joint: Toward precision management of osteoarthritis (Review)

Ruipu Zhang, Liang Zhang, Yiqun Wang, Xin Kang, Jiang Zheng
Article Number: 226
Published online on: 22 June 2026

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Retraction Open Access

[Retracted] Protection of telomeres 1 protein levels are associated with telomere length in gastric cancer

Kiyomu Fujii, Tomonori Sasahira, Yukiko Moriwaka, Naohide Oue, Wataru Yasui, Hiroki Kuniyasu
Article Number: 225
Published online on: 22 June 2026

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Article Open Access

Molecular mechanism of hydromorphone preconditioning in cerebral ischemia/reperfusion‑induced inflammatory injury

Jing Yao, Zeqing Huang, Songze Li, Minghui Lun, Jianing Fan
Article Number: 224
Published online on: 18 June 2026

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Article Open Access

Oridonin ameliorates ulcerative colitis by regulating the PI3K/AKT/mTOR signaling pathway to activate autophagy

Zhongxing Miao, Baohong Liu, Xingzhi Zhou, Mengru Lu, Ni Jia, Huamin Zhang, Ying Qi, Xiaoyu Tan, Qinggao Zhang
Article Number: 223
Published online on: 18 June 2026

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Article

Arsenic exposure and skin cancer: Mechanisms, clinical evidence and public health implications (Review)

Dimitrios A. Andreikos, Michael Aschner, Dimitrios C. Ziogas, Aristidis Tsatsakis, Demetrios A. Spandidos
Article Number: 222
Published online on: 18 June 2026

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Review Open Access

Targeting glutathione metabolism for tumor radiosensitization (Review)

Haonan Xu, Meng Du, Xiaowen Liang, Xilin Xiao, Zhiyi Chen
Article Number: 221
Published online on: 16 June 2026

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Review Open Access

Effects of exercise‑derived extracellular vesicles: Epigenetic regulatory mechanisms and protective roles (Review)

Xinxin Zhang, Biao Zhang
Article Number: 220
Published online on: 15 June 2026

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Article Open Access

Moderate downregulation of NDUFA13 promotes cardiomyocytes proliferation and heart regeneration through the glycolysis/c‑Myc/Ccnd1 axis

Ying Gao, Ningjing Qian, Junyan Jin, Jiayi Liu, Bingqi Wang, Yaping Wang
Article Number: 219
Published online on: 12 June 2026

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Correction Open Access

[Corrigendum] (‑)‑Epigallocatechin‑3‑gallate attenuates myocardial injury induced by ischemia/reperfusion in diabetic rats and in H9c2 cells under hyperglycemic conditions

Yang Wu, Zhong-Yuan Xia, Bo Zhao, Yan Leng, Juan Dou, Qing-Tao Meng, Shao-Qing Lei, Zhi-Ze Chen, Jie Zhu
Article Number: 218
Published online on: 10 June 2026

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Article Open Access

Melatonin ameliorates circadian rhythm disruption induced erectile dysfunction by inhibiting oxidative stress mediated pyroptosis via Nrf2/HO‑1 axis

Qingtao Yang, Wei Li, Qi Yu, Jiang Shi, Lu Yang, Jun Qiao, Xi Wei, Changshi Gu, Fa Sun, Tao Li
Article Number: 217
Published online on: 09 June 2026

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Review Open Access

Spatial architecture of immunometabolism: Mitochondrial‑organelle interfaces in immune signaling (Review)

Yaping Wu, Hao Yu, Ling Xia, Li Yang, Yu Zhou, Qian Yu
Article Number: 216
Published online on: 08 June 2026

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Review Open Access

Urea cycle dysregulation and arginine pathways in the pathogenesis of NAFLD and NASH (Review)

Boying Zhu, Chaoyang Wang, Peng Liu, Zhifeng Qu, Ran Qi, Shengjiang Chen, Huanzhang Niu
Article Number: 215
Published online on: 08 June 2026

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Article Open Access

Withaferin A, a candidate drug for lupus nephritis, confers renal protection via Pon1‑mediated attenuation of oxidative stress

Miao Xue, Junshuai Feng, Xiaorong Mao
Article Number: 214
Published online on: 08 June 2026

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Retraction Open Access

[Retracted] Classical dendritic cells regulate acute lung inflammation and injury in mice with lipopolysaccharide‑induced acute respiratory distress syndrome

Lang Li, Liang Dong, Dan Zhao, Fei Gao, Jie Yan
Article Number: 213
Published online on: 08 June 2026

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Review Open Access

Plant‑derived natural products alleviate dexamethasone‑induced skeletal muscle atrophy by modulating FoxO (Review)

Wei Dai, Jiabin Wu, Xiaotong Ma, Mingyu Wu, Ke Li, Haoyang Gao, Wenhong Wang, Weihua Xiao
Article Number: 212
Published online on: 05 June 2026

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Review Open Access

Functional hydrogels in cardiovascular therapy: Design, applications and clinical challenges (Review)

Zheming Yang, Jiayin Li, Lingxiao Zhao, Dali Zhang, Chenghui Yan, Dan Liu, Yaling Han
Article Number: 211
Published online on: 04 June 2026

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Review Open Access

Experimental rodent models of cardiorenal syndrome types 3 and 4: Insights and clinical relevance (Review)

Stefanny M. Figueroa, Siyi Huang, Javier Reyes‑Osorio, Jean-Jacques Boffa, Cristián A. Amador, Christos E. Chadjichristos, Louis Boutin
Article Number: 210
Published online on: 04 June 2026

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Expression of Concern Open Access

[Expression of Concern] Novel insights into the role of HSP90 in cytoprotection of H2S against chemical hypoxia‑induced injury in H9c2  cardiac myocytes

Zhanli Yang, Chuntao Yang, Liangcan Xiao, Xinxue Liao, Aiping Lan, Xiuyu Wang, Ruixian Guo, Peixi Chen, Chengheng Hu, Jianqiang Feng
Article Number: 209
Published online on: 03 June 2026

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Article Open Access

Microbiota‑derived indole‑3‑propionic acid reprograms bone marrow stem cell fate via PPARγ suppression to rescue osteoporosis

Jinwu Bai, Ruideng Wang, Jixing Fan, Shilong Su, Gao Si, Qinyong You, Ao Sun, Daole Hu, Shan Gao, Yang Lv, Fang Zhou
Article Number: 208
Published online on: 03 June 2026

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Article Open Access

Lactate regulates osteoclastogenesis via H3k18la in osteoarthritis

Zhibo Fan, Qiyue Fu, Tao Sun, Yutong Zhong, Yuefan Ma, Jingwei Jian, Shuosheng Yuan, Shenghong Li, Xiaomei Xu
Article Number: 207
Published online on: 02 June 2026

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Retraction Open Access

[Retracted] miR‑215 promotes epithelial to mesenchymal transition and proliferation by regulating LEFTY2 in endometrial cancert

Xiaoxu Gao, Yan Cai, Ruifang An
Article Number: 206
Published online on: 02 June 2026

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Review

Multi‑scale experimental models for the study of angiogenesis (Review)

Qin Yu, Jiarui Hu, Shuangshuang Yuan, Jiexia Gan, Mao Luo, Jianbo Wu, Liqun Wang
Article Number: 205
Published online on: 28 May 2026

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Review Open Access

Targeting lactylation in hepatocellular carcinoma: Mechanistic insights and therapeutic opportunities (Review)

Lianting Chen, Feiqiong Gao, Qianru Mei, Yujie Li, Qun Cai, Xudong Feng
Article Number: 204
Published online on: 28 May 2026

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Article Open Access

Oxygen‑sensing histone demethylase KDM6A modulates chondrocyte‑to‑osteoblast transdifferentiation by activating the Wnt/β‑catenin pathway

Yi Rong, Hao Yu, Heng Yin, Shaoshuo Li, Jianwei Wang, Zhongyuan Shen, Xinxin Ding, Fanchen Bu, Tianyi Dai, Gean Wu, Zhen Hua
Article Number: 203
Published online on: 28 May 2026

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September-2026 Volume 58 Issue 3

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Journal Metrics

Impact Factor: 8.5

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Endocrine‑metabolic imbalance drives osteoarthritis: From whole‑joint pathobiology to precision therapy (Review)

Ruhui Yang, Haimin Zeng, Qi Xiao, Yining Xie, Yi Long, Xiang Chen
Article Number: 252
Published online on: 09 July 2026

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Expression of Concern Open Access

[Expression of Concern] Roles and mechanisms of action of HNF‑4α in the hepatic differentiation of WB‑F344 cells

Yumeng Shi, Dehua Zhou, Bingyi Wang, Deren Zhou, Baomin Shi
Article Number: 251
Published online on: 08 July 2026

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Article Open Access

Phenylalanine exacerbates psoriasiform inflammation through NF‑κB‑mediated dendritic cell activation and Th17 polarization

Yaohan Xu, Jing Pan, Jie Chen, Yutao Zhu, Miaolian Cai, Zeyu Ma, Siji Chen, Tianze Yu, Yushu Wei, Jingying Pan, Kunliang Luo, Yinjing Song, Stijn Van Der Veen, Hao Cheng
Article Number: 250
Published online on: 08 July 2026

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Review Open Access

Protective effects of Astragaloside IV on various liver diseases: From chemistry to herbal medicines (Review)

Jialu Shi, Xiaoyu Zhou, Jiabin Wu, Liru Zeng, Xia Wang, Wei Li, Xiao Huang, Xiaoyu Deng, Wenhong Wang
Article Number: 249
Published online on: 07 July 2026

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Review Open Access

GRP78 dysregulation: A proposed molecular mechanism linking the tumor microenvironment to sepsis susceptibility in patients with cancer (Review)

Hang Ruan, Meipeng Zhu, Shi-Yan Liu, Li-Juan Zou, Shu-Sheng Li
Article Number: 248
Published online on: 07 July 2026

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Review Open Access

FGFR1 signaling in rheumatoid arthritis: Mechanisms of bone destruction and therapeutic targeting (Review)

Changzhong Qian, Zhenyu Zhang, Xian Wu, Huibo Ti, Junjie Wu, Zhengdong Yuan, Xia Li, Feng-Lai Yuan
Article Number: 247
Published online on: 06 July 2026

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Retraction Open Access

[Retracted] β‑catenin signaling induces the osteoblastogenic differentiation of human pre‑osteoblastic and bone marrow stromal cells mainly through the upregulation of osterix expression

Bo Liu, Song Wu, Lihua Han, Chaoyue Zhang
Article Number: 246
Published online on: 06 July 2026

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Article Open Access

Single‑cell atlas reveals a Wilms' tumor 1‑mediated axis driving granulosa cell senescence in human ovarian aging

Yanfang Du, Congyu Zhou, Yanpeng Tian, Zhongkang Li, Xianghua Huang
Article Number: 245
Published online on: 03 July 2026

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Review Open Access

TRPV1‑mediated central sensitisation: Core mechanisms of migraine chronification and novel targeted therapeutic strategies (Review)

Mingxia Zhang, Yuting Pu, Yujie Zhang, Jia Hu, Shuangyang Li, Hongmei Tang, Bangjiang Fang, Xue Bai
Article Number: 244
Published online on: 02 July 2026

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Correction Open Access

[Corrigendum] Arginine ADP‑ribosyltransferase 1 promotes angiogenesis in colorectal cancer via the PI3K/Akt pathway

Lian Yang, Ming Xiao, Xian Li, Yi Tang, Ya-Lan Wang
Article Number: 243
Published online on: 02 July 2026

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Review Open Access

Research progress on the chemical and pharmacological effects of Semen Strychni (Review)

Jingxin Mao, Xin Du, Dan Zeng, Xin Luo, Yan Li
Article Number: 242
Published online on: 02 July 2026

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Article Open Access

FLI1 enhances the malignant phenotype of glioma cells and exerts immunomodulatory effects through feedback crosstalk with exonic circRNA FECR1 and interferon‑induced ISG15

Xue Wen, Xiaoyi Gu, Xu Yan, Naifei Chen, Lei Zhou, Hui Li, Andrew R. Hoffman, Wei Li, Ji-Fan Hu, Jiuwei Cui
Article Number: 241
Published online on: 01 July 2026

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Review Open Access

Role of ZEB1 in angiogenesis and therapeutic potential (Review)

Ruoxin Ren, Chunxiao Yan, Yao Xiang, Lin Jin, Fang Cheng, Lijun Zhang
Article Number: 240
Published online on: 01 July 2026

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Review Open Access

Endothelial dysfunction: A central mechanism linking autosomal dominant polycystic kidney disease and intracranial aneurysms (Review)

Xiaohong Xu, Ruyi Xu, Liexiang Zhang
Article Number: 239
Published online on: 01 July 2026

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Correction Open Access

[Corrigendum] Effect of SDF‑1/CXCR4 axis on the migration of transplanted bone mesenchymal stem cells mobilized by erythropoietin toward lesion sites following spinal cord injury

Jun Li, Weichun Guo, Min Xiong, Heng Han, Jie Chen, Dan Mao, Bing Tang, Hualong Yu, Yun Zeng
Article Number: 238
Published online on: 01 July 2026

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Review Open Access

Exercise and fluoxetine in Alzheimer's disease: Molecular mechanisms of synergistic and antagonistic effects (Review)

Mei Wu, Yan Li
Article Number: 237
Published online on: 30 June 2026

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Review Open Access

Oral‑gut axis in systemic disease: A barrier‑metabolism‑immunity three‑dimensional regulatory model (Review)

Qing Li, Mingrong Cheng, Weiwei Li, Xiaoyue Wang, Xiaoqing Liu, Yujie Yan
Article Number: 236
Published online on: 30 June 2026

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Review Open Access

ABCG2 transporter: Structural and functional associations with gout (Review)

Muhammad Arslan Asif, Zeshan Zulfiqar, Bahar E. Mustafa, Usman Nazir, Jiamen Sun, Zhichang Wang, Yalei Cui, Sun Hao, Liu Boshuai, Yinghua Shi
Article Number: 235
Published online on: 30 June 2026

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Review Open Access

Neuropilin‑1: Emerging roles in nerve‑vessel‑bone coupling during fracture repair (Review)

Keyue Zhang, Tong Li, Huan Liu, Huibo Ti, Zhenyu Zhang, Zhengdong Yuan, Junjie Wu, Xielin Yan, Zixin Luo, Haiting Hu, Xingchen Yao, Shuwen Shi, Xian Wu, Feng-Lai Yuan, Xiao Chen
Article Number: 234
Published online on: 30 June 2026

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Correction Open Access

[Corrigendum] Crocin exerts anti‑inflammatory and anti‑catabolic effects on rat intervertebral discs by suppressing the activation of JNK

Kang Li, Yan Li, Zhenjiang Ma, Jie Zhao
Article Number: 233
Published online on: 29 June 2026

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Review Open Access

Skeletal muscle‑derived extracellular vesicles in multi‑organ degenerative disease: Mechanisms and therapeutic delivery perspectives (Review)

Xianji Wei, Chengyan Guo, Wei Zhang, Guanyi Wang, Wenjing Li, Binghong Gao, Bo Gao, Lingli Zhang
Article Number: 232
Published online on: 26 June 2026

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