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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
January-2021 Volume 47 Issue 1

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Approaches towards fighting the COVID‑19 pandemic (Review)

Shih‑Chang Tsai, Chi‑Cheng Lu, Da‑Tian Bau, Yu‑Jen Chiu, Yu‑Ting Yen, Yuan‑Man Hsu, Chih‑Wei Fu, Sheng‑Chu Kuo, Yu‑Shiang Lo, Hong‑Yi Chiu, Yu‑Ning Juan, Fuu‑Jen Tsai, Jai‑Sing Yang
Pages: 3-22
Published online on: 20 November 2020

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Review Open Access

BCL2‑regulated apoptotic process in myocardial ischemia‑reperfusion injury (Review)

Anna Yu. Korshunova, Mikhail L. Blagonravov, Ekaterina V. Neborak, Sergey P. Syatkin, Anastasia P. Sklifasovskaya, Said M. Semyatov, Enzo Agostinelli
Pages: 23-36
Published online on: 04 November 2020

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Review Open Access

Antioxidant and anti‑inflammatory mechanisms of action of astaxanthin in cardiovascular diseases (Review)

Carolina Parga Martins Pereira, Ana Carolina Remondi Souza, Andrea Rodrigues Vasconcelos, Pietra Sacramento Prado, José João Name
Pages: 37-48
Published online on: 04 November 2020

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Review Open Access

CircRNAs open a new era in the study of cardiovascular disease (Review)

Zhikang Yu, Qingyan Huang, Qunji Zhang, Heming Wu, Zhixiong Zhong
Pages: 49-64
Published online on: 18 November 2020

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Review Open Access

Mechanism overview and target mining of atherosclerosis: Endothelial cell injury in atherosclerosis is regulated by glycolysis (Review)

Ruiying Wang, Min Wang, Jingxue Ye, Guibo Sun, Xiaobo Sun
Pages: 65-76
Published online on: 24 November 2020

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Review Open Access

Role of circular RNAs and long non‑coding RNAs in the clinical translation of gastric cancer (Review)

Bo Cao, Guoxiao Liu, Wang Zhang, Yajiao Shi, Bo Wei
Pages: 77-91
Published online on: 29 October 2020

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Review Open Access

Unraveling the roles of vitamin D status and melanin during Covid‑19 (Review)

Polytimi Sidiropoulou, Anca Oana Docea, Vasiliki Nikolaou, Martha-Spyridoula Katsarou, Demetrios A. Spandidos, Aristidis Tsatsakis, Daniela Calina, Nikolaos Drakoulis
Pages: 92-100
Published online on: 30 November 2020

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Article Open Access

Role of Asxl2 in non‑alcoholic steatohepatitis‑related hepatocellular carcinoma developed from diabetes

Zhiqiu Hu, Ziping Zhang, Fei Teng, Jinfeng Feng, Xubo Wu, Qimeng Chang
Pages: 101-112
Published online on: 04 November 2020

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Article Open Access

Pimozide augments bromocriptine lethality in prolactinoma cells and in a xenograft model via the STAT5/cyclin D1 and STAT5/Bcl‑xL signaling pathways

Zhengzheng Xiao, Jing Liang, Qing Deng, Chaojun Song, Xiaoli Yang, Zebin Liu, Zheng Shao, Kun Zhang, Xiaobin Wang, Zhengwei Li
Pages: 113-124
Published online on: 05 November 2020

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Article Open Access

Lactobacillus rhamnosus attenuates intestinal inflammation induced by Fusobacterium nucleatum infection by restoring the autophagic flux

Caihan Duan, Xuelian Tang, Weijun Wang, Wei Qian, Xiaochao Fu, Xiaohua Deng, Shunchang Zhou, Chaoqun Han, Xiaohua Hou
Pages: 125-136
Published online on: 03 November 2020

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Article Open Access

Toll‑like receptor 4 activates the NLRP3 inflammasome pathway and periodontal inflammaging by inhibiting Bmi‑1 expression

Zi‑Yue Qin, Xin Gu, Yu‑Lian Chen, Jia‑Bao Liu, Chen‑Xing Hou, Shi‑Yu Lin, Nan‑Nan Hao, Yan Liang, Wu Chen, Hao‑Yu Meng
Pages: 137-150
Published online on: 11 November 2020

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Article Open Access

MicroRNA‑126 suppresses the proliferation and migration of endothelial cells in experimental diabetic retinopathy by targeting polo‑like kinase 4

Yarong Zheng, Yi Liu, Lili Wang, Hanchun Xu, Zhiqing Lu, Yaling Xuan, Wenjing Meng, Lin Ye, Dejia Fang, Yekai Zhou, Kunmao Ke, Yanli Liu, Meixia An
Pages: 151-160
Published online on: 30 October 2020

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Article Open Access

Mitochondrial gene COX2 methylation and downregulation is a biomarker of aging in heart mesenchymal stem cells

Xiguang Sun, Zilong Wang, Xiaoqiang Cong, Yudan Lv, Zhuo Li, Li Rong, Tianye Yang, Dehai Yu
Pages: 161-170
Published online on: 25 November 2020

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Article Open Access

LINC00473 rescues human bone marrow mesenchymal stem cells from apoptosis induced by dexamethasone through the PEBP1‑mediated Akt/Bad/Bcl‑2 signaling pathway

Yingxing Xu, Yaping Jiang, Yingzhen Wang, Zhiping Zhao, Tao Li
Pages: 171-182
Published online on: 11 November 2020

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Article Open Access

Elevated intracranial pressure induces IL‑1β and IL‑18 overproduction via activation of the NLRP3 inflammasome in microglia of ischemic adult rats

Hongguang Ding, Ya Li, Miaoyun Wen, Xinqiang Liu, Yongli Han, Hongke Zeng
Pages: 183-194
Published online on: 03 November 2020

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Article Open Access

YAP and Wnt3a independently promote AECIIs proliferation and differentiation by increasing nuclear β‑catenin expression in experimental bronchopulmonary dysplasia

Xianxian Jia, Bo Wu, Jinhui Huang, Lin Fan, Miao Yang, Wei Xu
Pages: 195-206
Published online on: 18 November 2020

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Article Open Access

Prostaglandin E2 serves a dual role in regulating the migration of dendritic cells

Ge Diao, Jie Huang, Xiuhui Zheng, Xinwei Sun, Min Tian, Jian Han, Jianxin Guo
Pages: 207-218
Published online on: 26 November 2020

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Article Open Access

Transcriptomic landscaping of core genes and pathways of mild and severe psoriasis vulgaris

Saumya Choudhary, Rishika Anand, Dibyabhaba Pradhan, Banajit Bastia, Shashi Nandar Kumar, Harpreet Singh, Poonam Puri, George Thomas, Arun Kumar Jain
Pages: 219-231
Published online on: 27 October 2020

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Article Open Access

Circular RNA CSNK1G1 promotes the progression of osteoarthritis by targeting the miR‑4428/FUT2 axis Retraction in /10.3892/ijmm.2022.5080

Jianwei Xiao, Rongsheng Wang, Weijian Zhou, Xu Cai, Zhizhong Ye
Pages: 232-242
Published online on: 27 October 2020

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Article Open Access

Echinacea polysaccharide attenuates lipopolysaccharide‑induced acute kidney injury via inhibiting inflammation, oxidative stress and the MAPK signaling pathway

Qiumei Shi, Wuying Lang, Shiyong Wang, Guangyu  Li, Xue Bai, Xijun Yan, Haihua Zhang
Pages: 243-255
Published online on: 23 October 2020

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Article Open Access

TGF‑β1‑induced autophagy activates hepatic stellate cells via the ERK and JNK signaling pathways

Jing Zhang, Na Jiang, Jian Ping, Lieming Xu
Pages: 256-266
Published online on: 03 November 2020

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Article Open Access

Septic serum mediates inflammatory injury in human umbilical vein endothelial cells via reactive oxygen species, mitogen activated protein kinases and nuclear factor‑κB

Shouzhu Xu, Yu Yan, Zhijiao Yan, Jie Xu, Baoning Qi, Juan Li, Zhigang Zhang, Yuanping Han, Jing Zhao
Pages: 267-275
Published online on: 10 November 2020

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Article Open Access

A novel peptide relieves endothelial cell dysfunction in preeclampsia by regulating the PI3K/mTOR/HIF1α pathway

Lu Xue, Kaipeng Xie, Lan Wu, Xiang Yu, Wei Long, Chanjuan Li, Ruizhe Jia, Hongjuan Ding
Pages: 276-288
Published online on: 19 November 2020

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Article Open Access

Role of ferroptosis induced by a high concentration of calcium oxalate in the formation and development of urolithiasis

Ziqi He, Wenbiao Liao, Qianlin Song, Bin Li, Junwei Liu, Yunhe Xiong, Chao Song, Sixing Yang
Pages: 289-301
Published online on: 23 October 2020

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Article Open Access

Astragaloside IV attenuates cerebral ischemia‑reperfusion injury in rats through the inhibition of calcium‑sensing receptor‑mediated apoptosis

Shu‑Jin Du, Ying Zhang, Yan‑Meng Zhao, Ya‑Jie Dong, Jing‑Long Tang, Xiao‑Hong Zhou, Wei‑Juan Gao
Pages: 302-314
Published online on: 02 November 2020

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Article Open Access

Dendritic cell‑derived exosomal miR‑494‑3p promotes angiogenesis following myocardial infarction Corrigendum in /10.3892/ijmm.2022.5096

Haibo Liu, Youming Zhang, Jie Yuan, Wei Gao, Xin Zhong, Kang Yao, Li Lin, Junbo Ge
Pages: 315-325
Published online on: 02 November 2020

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Article Open Access

Zinc and SARS‑CoV‑2: A molecular modeling study of Zn interactions with RNA‑dependent RNA‑polymerase and 3C‑like proteinase enzymes

Ali Pormohammad, Nadia K. Monych, Raymond J. Turner
Pages: 326-334
Published online on: 18 November 2020

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Article Open Access

Resveratrol inhibits the progression of cervical cancer by suppressing the transcription and expression of HPV E6 and E7 genes

Xiaodong Sun, Pan Fu, Lixia Xie, Senmao Chai, Qianqian Xu, Lian Zeng, Xuanbin Wang, Nan Jiang, Ming Sang
Pages: 335-345
Published online on: 17 November 2020

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Article Open Access

Bleomycin A5 suppresses Drp1‑mediated mitochondrial fission and induces apoptosis in human nasal polyp‑derived fibroblasts

Fan Wu, Yun Ma, Jingyi Wang, Huashuang Ou, Hua Dang, Yiqing Zheng, Peng Tian, Hua Zou
Pages: 346-360
Published online on: 23 November 2020

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Article Open Access

SOX11 and FAK participate in the stretch‑induced mechanical injury to alveolar type 2 epithelial cells

Mingxing Fang, Tieling Xu, Shujuan Fan, Na Liu, Luping Li, Junxia Gao, Wenbin Li
Pages: 361-373
Published online on: 20 November 2020

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Article

SphK1 promotes development of non‑small cell lung cancer through activation of STAT3

Yuefeng Ma, Xin Xing, Ranran Kong, Chuantao Cheng, Suoni Li, Xiaoping Yang, Shaomin Li, Feng Zhao, Liangzhang Sun, Gang Cao
Pages: 374-386
Published online on: 23 November 2020

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Article

Long noncoding RNA KCNQ1OT1 contributes to tumor growth and activates Wnt/β‑catenin signaling in osteosarcoma by targeting the miR‑3666/KLF7 axis

Aijun Huang, Song Jin, Weidong Han, Yiming Wang, Shuqiang Ma, Zengrong Wang, Kun Lin, Qingbao Zou, Jingying Zhou, Zhongtan Li, Liping Chen
Pages: 387-396
Published online on: 23 October 2020

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Article

LINC00324 facilitates cell proliferation through competing for miR‑214‑5p in immature ovarian teratocarcinoma

Meiling Chen, Min Zhang, Ling Xie, Sanshan Wu, Yuanyuan Zhong
Pages: 397-407
Published online on: 25 November 2020

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Correction Open Access

[Corrigendum] Panax notoginseng saponins prevent senescence and inhibit apoptosis by regulating the PI3K‑AKT‑mTOR pathway in osteoarthritic chondrocytes

Yubiao Zhang, Weisong Cai, Guangtao Han, Siqi Zhou, Jianping Li, Mao Chen, Haohuan Li
Pages: 408-409
Published online on: 11 November 2020

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Correction Open Access

[Corrigendum] Connexin 43 reduces susceptibility to sympathetic atrial fibrillation

Beibei Luo, Yifei Yan, Zhiyu Zeng, Zhengnan Zhang, Haide Liu, Hao Liu, Jinyi Li, Weiqiang Huang, Jiangtao Wu, Yan He
Pages: 410-410
Published online on: 29 October 2020

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Correction Open Access

[Corrigendum] SiRNA‑mediated PIAS1 silencing promotes inflammatory response and leads to injury of cerulein‑stimulated pancreatic acinar cells via regulation of the P38MAPK signaling pathway

Ping Chen, Liya Huang, Yongping Zhang, Minmin Qiao, Yaozong Yuan
Pages: 411-411
Published online on: 30 November 2020

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Journal Cover
March-2026 Volume 57 Issue 3

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

Ginkgolide C alleviates atherosclerosis via activating Nrf2 to inhibit ROS‑dependent NLRP3 inflammasome activation

Rui Zhang
Article Number: 75
Published online on: 27 January 2026

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Review Open Access

MicroRNA‑microbiome cross‑kingdom networks drive inflammatory bowel disease through dynamic regulatory ecosystems (Review)

Liping Liang, Xiaoyan Liu, Bang Li, Huyi Lei, Zibo Tang, Shijie Mai, Chenghai Yang, Yongjian Zhou, Shaoheng Zhang, Le Liu
Article Number: 74
Published online on: 27 January 2026

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Mechanistic insights into pancreatic cancer progression from circadian rhythm disruption and gut microbiota dysbiosis (Review)

Yang Liu, Yongfeng Li, Heng Ma, Shichang Deng, Chao Cheng
Article Number: 73
Published online on: 26 January 2026

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Retraction Open Access

[Retracted] miR‑124‑3p inhibits the viability and motility of glioblastoma multiforme by targeting RhoG  

Shan Cai, Chao-Jia Shi, Jian-Xiang Lu, Yan-Pei Wang, Tian Yuan, Xiang-Peng Wang
Article Number: 72
Published online on: 26 January 2026

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Review Open Access

Natural products as multi‑target therapies for sepsis‑induced myocardial dysfunction (Review)

Fei Tang, Dong Liu, Shi-Chao Zhu, Hui-Min Zhou, Xue-Wen Qiu
Article Number: 71
Published online on: 22 January 2026

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Review Open Access

MTHFR‑folate axis as a modulator of the epigenetic landscape in autoimmune diseases (Review)

Pablo Michael Navarro‑Rodríguez, Ramón Francisco Bajeca‑Serrano, Francisco Javier Turrubiates‑Hernández, Hazael Ramiro Ceja‑Gálvez, Jorge Hernández‑Bello, Cristian Oswaldo Hernández‑Ramírez, Saúl Ramírez‑de Los Santos, José Francisco Muñoz‑Valle
Article Number: 70
Published online on: 22 January 2026

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Article Open Access

Natural compound 5,7,8‑trimethoxyflavone mitigates radiation‑induced lung injury by suppressing EMT and PI3K/Akt pathway

Cui-Cui Gong, Hua-Kang Li, Yuan-Zhen Mi, Jun-Yang Chen, Zeng-Yi Fang, Shun-Lian Fu, Li Quan, Bing Lin, Jin-Yi Lang, Qiu Chen, Ke Xu, Mei-Hua Chen
Article Number: 69
Published online on: 21 January 2026

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Review Open Access

Epigenetic dysregulation of B‑cells in autoimmune diseases and lymphomas (Review)

Yuxing Li, Yujiao Gong, Jiaxing Zhao, Rensen Ran
Article Number: 68
Published online on: 21 January 2026

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Review Open Access

Research progress on the effects of macrophage‑derived exosomes on muscle factors IGF‑1 and FGF‑2 mediating musculoskeletal crosstalk molecular signaling pathway on bone metabolism (Review)

Ruo-Mei Cui, Mai Zheng, Jian-Bin Hong, Zheng-Xiang Wang, Yu-Fang Cun, Shu-Ji Gao, Yan-Lin Zhu, Zi-Bin Yang, Ming-Wei Liu
Article Number: 67
Published online on: 21 January 2026

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Expression of Concern Open Access

[Expression of Concern] Long non‑coding RNA SNHG20 promotes bladder cancer via activating the Wnt/β‑catenin signalling pathway

Qingsong Zhao, Saiyue Gao, Qingyan Du, Ye Liu
Article Number: 66
Published online on: 21 January 2026

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Review Open Access

Mangiferin in human disease: Multifaceted mechanisms and applications (Review)

Yaling Dai, Qiuling Huang, Mengquan Tan, Zhifu Wang, Cai Jiang, Zheng Liu, Shenghang Zhang, Siyuan Song
Article Number: 65
Published online on: 21 January 2026

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Article

Deciphering the CAF‑LCN2 axis: Key to overcoming anti‑PD‑L1 immunotherapy resistance in lung cancer

Dan Xiao, Jing Yang, Jianying Zhou, Zhenzhen Hu, Ting Zhang
Article Number: 64
Published online on: 19 January 2026

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Retraction Open Access

[Retracted] DDAH2 alleviates myocardial fibrosis in diabetic cardiomyopathy through activation of the DDAH/ADMA/NOS/NO pathway in rats

Zhen-Dong Zhu, Ji-Ming Ye, Xue-Mei Fu, Xue-Chang Wang, Ji-Yun Ye, Xin-Ran Wu, Peng Hua, Yu-Qiong Liao, Wei Xuan, Jin-Lan Duan, Wei-Yuan Li, Hui Fu, Zhong-Hua Xia, Xuan Zhang
Article Number: 63
Published online on: 19 January 2026

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Review Open Access

Beyond hepatic stellate cell heterogeneity: Resolving fibrosis, restoring regeneration (Review)

Chang Gao, Guiqing Chen, Hongyan Jia, Hong Zhu, Yun Cai, Dakai Yang, Kai Zhao
Article Number: 62
Published online on: 14 January 2026

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Correction Open Access

[Corrigendum] CDKN2A (p16INK4A) affects the anti‑tumor effect of CDK inhibitor in somatotroph adenomas

Yiyuan Chen, Zhenye Li, Qiuyue Fang, Hongyun Wang, Chuzhong Li, Hua Gao, Yazhuo Zhang
Article Number: 61
Published online on: 14 January 2026

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Review Open Access

Harnessing MSC‑derived exosomes to modulate the pathophysiology of ASD: Recent advances and therapeutic implications (Review)

Zhaojian Sun, Nouman Amjad, Majid Muhammad, Zhiyuan Li
Article Number: 60
Published online on: 13 January 2026

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Retraction Open Access

[Retracted] Mechanism of cell death induced by silica nanoparticles in hepatocyte cells is by apoptosis

Ye Yang, Xinjing Du, Qiang Wang, Jianwei Liu, Enguo Zhang, Linlin Sai, Cheng Peng, Martin F. Lavin, Abrey Jie Yeo, Xu Yang, Hua Shao, Zhongjun Du
Article Number: 59
Published online on: 12 January 2026

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Review Open Access

ZG16B: A key regulator of tumor progression and immune microenvironment modulation in cancer (Review)

Xing-Ming Chen, Yu-Bo Liang, Jin-Xiang Zuo, Zi-Sheng Yang, Le-Yu Zhang, Xin-Yu Zhang, Ping Wan, Yang Ke
Article Number: 58
Published online on: 09 January 2026

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Retraction Open Access

[Retracted] Silica nanoparticles induce cardiomyocyte apoptosis via the mitochondrial pathway in rats following intratracheal instillation

Zhongjun Du, Shangya Chen, Guanqun Cui, Ye Yang, Enguo Zhang, Qiang Wang, Martin F. Lavin, Abrey J. Yeo, Cunxiang Bo, Yu Zhang, Chao Li, Xiaoshan Liu, Xu Yang, Cheng Peng, Hua Shao
Article Number: 57
Published online on: 05 January 2026

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Review Open Access

Role of cuproptosis in digestive system tumors (Review)

Li Zhang, Yongpeng Cheng, Lulu Tang, Jiaxing Zhu, Biguang Tuo
Article Number: 56
Published online on: 02 January 2026

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Review Open Access

Environmental exposure to air pollution and climate: Intersecting the impact on ear and nose health and chemosensory function (Review)

Yu-Chen Zhang, Lei Zhang, Ping-Ting Zhou, Zi-Hui Xie, Wen-Jie Zhang, Min Fan, Yan-Xun Han, Ye-Hai Liu, Yu-Chen Liu
Article Number: 55
Published online on: 31 December 2025

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Role and mechanisms of ferroptosis in cognitive impairment: From molecular pathways to therapeutic targets (Review)

Shenghui Ge, Deyue Kong, Shuyue Fan, Yi Luo, Xiao Yin, Zehua Jin, Wenqing Xia, Jianhua Ma
Article Number: 54
Published online on: 30 December 2025

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Review Open Access

The GPR124‑Wnt‑PPARγ regulatory axis: Molecular mechanisms and therapeutic implications in chronic inflammatory diseases (Review)

Ming-Wang Cui, Si-Yu Tao, Tao Wen, Zhu-Ling Guo
Article Number: 53
Published online on: 30 December 2025

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Review Open Access

Advances in RPGR gene therapy for X‑linked retinitis pigmentosa: From preclinical insights to clinical application (Review)

Yushan Long, Jia Qi, Wenliang Zhang, Huan Qin, Kai Yao
Article Number: 52
Published online on: 30 December 2025

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April-2026 Volume 57 Issue 4

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Role of vascular smooth muscle cell pathobiology in sepsis‑induced vasoplegia (Review)

Hang Ruan, Xiao-Yan Shen, Shi-Yan Liu, Shu-Sheng Li
Article Number: 87
Published online on: 06 February 2026

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Signalling pathways regulated by FSTL1 in inflammation and potential therapeutic applications (Review)

Changliang Ma, Jingxin Li, Wenting Jiang, Xiaoqiang Chen, Jianquan Liu, Xu Tao, Wencui Li, Zhiqin Deng, Zhe Zhao
Article Number: 86
Published online on: 05 February 2026

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Article Open Access

Hypothermic machine perfusion protects DCD graft liver from ischemia‑reperfusion injury by enhancing macrophage efferocytosis via KLF2‑NLRP3 signaling

Qin Deng, Zhongzhong Liu, Qifa Ye, Jia Liu, Zhihui Fu, Xingjian Zhang, Jun Luo, Zhongshan Lu, Pengpeng Yue, Jiansheng Xiao, Qi Xiao
Article Number: 85
Published online on: 05 February 2026

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Mechanistic advances in exercise‑mediated regulation of autophagy dysfunction in Alzheimer's disease (Review)

Wei Li, Wen-Hong Wang, Yi Song, Xu-Jiong Li, Yan Li, Xia Wang, Ting-Ting Tian, Xiao Huang, Li Zhao
Article Number: 84
Published online on: 04 February 2026

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Correction Open Access

[Corrigendum] p57KIP2‑mediated inhibition of human trophoblast apoptosis and promotion of invasion in vitro

Guo-Qian He, Guang-Yu Liu, Wen-Ming Xu, Hui-Juan Liao, Xing-Hui Liu, Guo-Lin He
Article Number: 83
Published online on: 04 February 2026

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Review Open Access

Lipid droplets beyond storage: Cellular metabolic modulator in the diabetic heart (Review)

Yongchun Liang, Xinbiao Fan, Xiaofei Geng, Yunfeng Jia, Wenyu Shang, Xitong Sun, Jun Ge, Guijun Ye, Boyu Zhu, Zheng Zhang, Yuxin Kang, Xiaoyu Shan, Junping Zhang
Article Number: 82
Published online on: 03 February 2026

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IMP metabolic mechanisms and IMPDH targeting strategies in tumor metabolic reprogramming and therapy (Review)

Hao Zhu, Hao Wang, Xia Li, Weisong Zhang, Yihao Wang, Qingze Tan, Dongxu Ying, Zhan Shi, Jianxiang Song
Article Number: 81
Published online on: 03 February 2026

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Article Open Access

Ebastine targets HER2/HER3 signaling and cancer stem cell traits to overcome trastuzumab resistance in HER2‑positive breast cancer

Eunsun Jung, Ji Young Kim, Dongmi Ko, Juyeon Seo, Sang Yoon Lee, Daeun Lee, Subeen Kim, Minsu Park, Seongjae Kim, Soeun Park, Kyoungmin Lee, Yong Koo Kang, Kee Dal Nam, Yoon-Jae Kim, Jae Hong Seo
Article Number: 80
Published online on: 02 February 2026

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Correction Open Access

[Corrigendum] Inhibition of acid‑sensing ion channel 1a attenuates acid‑induced activation of autophagy via a calcium signaling pathway in articular chondrocytes

Wen-Fan Gao, Ya-Yun Xu, Jin-Fang Ge, Fei-Hu Chen
Article Number: 79
Published online on: 02 February 2026

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Review Open Access

Immunological mechanisms and novel therapeutic strategies for sepsis‑associated acute kidney injury (Review)

Lu Xu, Wei Jiang, Lin Song, Jing Wang, Jiangquan Yu, Ruiqiang Zheng
Article Number: 78
Published online on: 30 January 2026

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Correction Open Access

[Corrigendum] Role of Smad3 signaling in the epithelial‑mesenchymal transition of the lens epithelium following injury

Fanlan Meng, Jun Li, Xiao Yang, Xiaoyong Yuan, Xin Tang
Article Number: 77
Published online on: 29 January 2026

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Review Open Access

Spatial metabolomics: A new tool for unravelling the metabolic disorders and heterogeneity in diabetic kidney disease (Review)

Hanfei Li, Yuxi Li, Bo Zhang, Wenhao Cheng, Guowei Ma, Jin Rong, Shiru Duan, Di Feng, Tingting Zhao
Article Number: 76
Published online on: 29 January 2026

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