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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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International Journal of Molecular Medicine

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
January-2021 Volume 47 Issue 1

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Approaches towards fighting the COVID‑19 pandemic (Review)

Shih‑Chang Tsai, Chi‑Cheng Lu, Da‑Tian Bau, Yu‑Jen Chiu, Yu‑Ting Yen, Yuan‑Man Hsu, Chih‑Wei Fu, Sheng‑Chu Kuo, Yu‑Shiang Lo, Hong‑Yi Chiu, Yu‑Ning Juan, Fuu‑Jen Tsai, Jai‑Sing Yang
Pages: 3-22
Published online on: 20 November 2020

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BCL2‑regulated apoptotic process in myocardial ischemia‑reperfusion injury (Review)

Anna Yu. Korshunova, Mikhail L. Blagonravov, Ekaterina V. Neborak, Sergey P. Syatkin, Anastasia P. Sklifasovskaya, Said M. Semyatov, Enzo Agostinelli
Pages: 23-36
Published online on: 04 November 2020

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Antioxidant and anti‑inflammatory mechanisms of action of astaxanthin in cardiovascular diseases (Review)

Carolina Parga Martins Pereira, Ana Carolina Remondi Souza, Andrea Rodrigues Vasconcelos, Pietra Sacramento Prado, José João Name
Pages: 37-48
Published online on: 04 November 2020

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Review Open Access

CircRNAs open a new era in the study of cardiovascular disease (Review)

Zhikang Yu, Qingyan Huang, Qunji Zhang, Heming Wu, Zhixiong Zhong
Pages: 49-64
Published online on: 18 November 2020

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Mechanism overview and target mining of atherosclerosis: Endothelial cell injury in atherosclerosis is regulated by glycolysis (Review)

Ruiying Wang, Min Wang, Jingxue Ye, Guibo Sun, Xiaobo Sun
Pages: 65-76
Published online on: 24 November 2020

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Role of circular RNAs and long non‑coding RNAs in the clinical translation of gastric cancer (Review)

Bo Cao, Guoxiao Liu, Wang Zhang, Yajiao Shi, Bo Wei
Pages: 77-91
Published online on: 29 October 2020

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Review Open Access

Unraveling the roles of vitamin D status and melanin during Covid‑19 (Review)

Polytimi Sidiropoulou, Anca Oana Docea, Vasiliki Nikolaou, Martha-Spyridoula Katsarou, Demetrios A. Spandidos, Aristidis Tsatsakis, Daniela Calina, Nikolaos Drakoulis
Pages: 92-100
Published online on: 30 November 2020

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Article Open Access

Role of Asxl2 in non‑alcoholic steatohepatitis‑related hepatocellular carcinoma developed from diabetes

Zhiqiu Hu, Ziping Zhang, Fei Teng, Jinfeng Feng, Xubo Wu, Qimeng Chang
Pages: 101-112
Published online on: 04 November 2020

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Article Open Access

Pimozide augments bromocriptine lethality in prolactinoma cells and in a xenograft model via the STAT5/cyclin D1 and STAT5/Bcl‑xL signaling pathways

Zhengzheng Xiao, Jing Liang, Qing Deng, Chaojun Song, Xiaoli Yang, Zebin Liu, Zheng Shao, Kun Zhang, Xiaobin Wang, Zhengwei Li
Pages: 113-124
Published online on: 05 November 2020

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Lactobacillus rhamnosus attenuates intestinal inflammation induced by Fusobacterium nucleatum infection by restoring the autophagic flux

Caihan Duan, Xuelian Tang, Weijun Wang, Wei Qian, Xiaochao Fu, Xiaohua Deng, Shunchang Zhou, Chaoqun Han, Xiaohua Hou
Pages: 125-136
Published online on: 03 November 2020

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Article Open Access

Toll‑like receptor 4 activates the NLRP3 inflammasome pathway and periodontal inflammaging by inhibiting Bmi‑1 expression

Zi‑Yue Qin, Xin Gu, Yu‑Lian Chen, Jia‑Bao Liu, Chen‑Xing Hou, Shi‑Yu Lin, Nan‑Nan Hao, Yan Liang, Wu Chen, Hao‑Yu Meng
Pages: 137-150
Published online on: 11 November 2020

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Article Open Access

MicroRNA‑126 suppresses the proliferation and migration of endothelial cells in experimental diabetic retinopathy by targeting polo‑like kinase 4

Yarong Zheng, Yi Liu, Lili Wang, Hanchun Xu, Zhiqing Lu, Yaling Xuan, Wenjing Meng, Lin Ye, Dejia Fang, Yekai Zhou, Kunmao Ke, Yanli Liu, Meixia An
Pages: 151-160
Published online on: 30 October 2020

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Article Open Access

Mitochondrial gene COX2 methylation and downregulation is a biomarker of aging in heart mesenchymal stem cells

Xiguang Sun, Zilong Wang, Xiaoqiang Cong, Yudan Lv, Zhuo Li, Li Rong, Tianye Yang, Dehai Yu
Pages: 161-170
Published online on: 25 November 2020

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Article Open Access

LINC00473 rescues human bone marrow mesenchymal stem cells from apoptosis induced by dexamethasone through the PEBP1‑mediated Akt/Bad/Bcl‑2 signaling pathway

Yingxing Xu, Yaping Jiang, Yingzhen Wang, Zhiping Zhao, Tao Li
Pages: 171-182
Published online on: 11 November 2020

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Article Open Access

Elevated intracranial pressure induces IL‑1β and IL‑18 overproduction via activation of the NLRP3 inflammasome in microglia of ischemic adult rats

Hongguang Ding, Ya Li, Miaoyun Wen, Xinqiang Liu, Yongli Han, Hongke Zeng
Pages: 183-194
Published online on: 03 November 2020

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Article Open Access

YAP and Wnt3a independently promote AECIIs proliferation and differentiation by increasing nuclear β‑catenin expression in experimental bronchopulmonary dysplasia

Xianxian Jia, Bo Wu, Jinhui Huang, Lin Fan, Miao Yang, Wei Xu
Pages: 195-206
Published online on: 18 November 2020

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Article Open Access

Prostaglandin E2 serves a dual role in regulating the migration of dendritic cells

Ge Diao, Jie Huang, Xiuhui Zheng, Xinwei Sun, Min Tian, Jian Han, Jianxin Guo
Pages: 207-218
Published online on: 26 November 2020

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Article Open Access

Transcriptomic landscaping of core genes and pathways of mild and severe psoriasis vulgaris

Saumya Choudhary, Rishika Anand, Dibyabhaba Pradhan, Banajit Bastia, Shashi Nandar Kumar, Harpreet Singh, Poonam Puri, George Thomas, Arun Kumar Jain
Pages: 219-231
Published online on: 27 October 2020

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Article Open Access

Circular RNA CSNK1G1 promotes the progression of osteoarthritis by targeting the miR‑4428/FUT2 axis Retraction in /10.3892/ijmm.2022.5080

Jianwei Xiao, Rongsheng Wang, Weijian Zhou, Xu Cai, Zhizhong Ye
Pages: 232-242
Published online on: 27 October 2020

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Article Open Access

Echinacea polysaccharide attenuates lipopolysaccharide‑induced acute kidney injury via inhibiting inflammation, oxidative stress and the MAPK signaling pathway

Qiumei Shi, Wuying Lang, Shiyong Wang, Guangyu  Li, Xue Bai, Xijun Yan, Haihua Zhang
Pages: 243-255
Published online on: 23 October 2020

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Article Open Access

TGF‑β1‑induced autophagy activates hepatic stellate cells via the ERK and JNK signaling pathways

Jing Zhang, Na Jiang, Jian Ping, Lieming Xu
Pages: 256-266
Published online on: 03 November 2020

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Article Open Access

Septic serum mediates inflammatory injury in human umbilical vein endothelial cells via reactive oxygen species, mitogen activated protein kinases and nuclear factor‑κB

Shouzhu Xu, Yu Yan, Zhijiao Yan, Jie Xu, Baoning Qi, Juan Li, Zhigang Zhang, Yuanping Han, Jing Zhao
Pages: 267-275
Published online on: 10 November 2020

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Article Open Access

A novel peptide relieves endothelial cell dysfunction in preeclampsia by regulating the PI3K/mTOR/HIF1α pathway

Lu Xue, Kaipeng Xie, Lan Wu, Xiang Yu, Wei Long, Chanjuan Li, Ruizhe Jia, Hongjuan Ding
Pages: 276-288
Published online on: 19 November 2020

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Article Open Access

Role of ferroptosis induced by a high concentration of calcium oxalate in the formation and development of urolithiasis

Ziqi He, Wenbiao Liao, Qianlin Song, Bin Li, Junwei Liu, Yunhe Xiong, Chao Song, Sixing Yang
Pages: 289-301
Published online on: 23 October 2020

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Article Open Access

Astragaloside IV attenuates cerebral ischemia‑reperfusion injury in rats through the inhibition of calcium‑sensing receptor‑mediated apoptosis

Shu‑Jin Du, Ying Zhang, Yan‑Meng Zhao, Ya‑Jie Dong, Jing‑Long Tang, Xiao‑Hong Zhou, Wei‑Juan Gao
Pages: 302-314
Published online on: 02 November 2020

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Dendritic cell‑derived exosomal miR‑494‑3p promotes angiogenesis following myocardial infarction Corrigendum in /10.3892/ijmm.2022.5096

Haibo Liu, Youming Zhang, Jie Yuan, Wei Gao, Xin Zhong, Kang Yao, Li Lin, Junbo Ge
Pages: 315-325
Published online on: 02 November 2020

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Article Open Access

Zinc and SARS‑CoV‑2: A molecular modeling study of Zn interactions with RNA‑dependent RNA‑polymerase and 3C‑like proteinase enzymes

Ali Pormohammad, Nadia K. Monych, Raymond J. Turner
Pages: 326-334
Published online on: 18 November 2020

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Resveratrol inhibits the progression of cervical cancer by suppressing the transcription and expression of HPV E6 and E7 genes

Xiaodong Sun, Pan Fu, Lixia Xie, Senmao Chai, Qianqian Xu, Lian Zeng, Xuanbin Wang, Nan Jiang, Ming Sang
Pages: 335-345
Published online on: 17 November 2020

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Article Open Access

Bleomycin A5 suppresses Drp1‑mediated mitochondrial fission and induces apoptosis in human nasal polyp‑derived fibroblasts

Fan Wu, Yun Ma, Jingyi Wang, Huashuang Ou, Hua Dang, Yiqing Zheng, Peng Tian, Hua Zou
Pages: 346-360
Published online on: 23 November 2020

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Article Open Access

SOX11 and FAK participate in the stretch‑induced mechanical injury to alveolar type 2 epithelial cells

Mingxing Fang, Tieling Xu, Shujuan Fan, Na Liu, Luping Li, Junxia Gao, Wenbin Li
Pages: 361-373
Published online on: 20 November 2020

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Article

SphK1 promotes development of non‑small cell lung cancer through activation of STAT3

Yuefeng Ma, Xin Xing, Ranran Kong, Chuantao Cheng, Suoni Li, Xiaoping Yang, Shaomin Li, Feng Zhao, Liangzhang Sun, Gang Cao
Pages: 374-386
Published online on: 23 November 2020

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Article

Long noncoding RNA KCNQ1OT1 contributes to tumor growth and activates Wnt/β‑catenin signaling in osteosarcoma by targeting the miR‑3666/KLF7 axis

Aijun Huang, Song Jin, Weidong Han, Yiming Wang, Shuqiang Ma, Zengrong Wang, Kun Lin, Qingbao Zou, Jingying Zhou, Zhongtan Li, Liping Chen
Pages: 387-396
Published online on: 23 October 2020

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Article

LINC00324 facilitates cell proliferation through competing for miR‑214‑5p in immature ovarian teratocarcinoma

Meiling Chen, Min Zhang, Ling Xie, Sanshan Wu, Yuanyuan Zhong
Pages: 397-407
Published online on: 25 November 2020

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Correction Open Access

[Corrigendum] Panax notoginseng saponins prevent senescence and inhibit apoptosis by regulating the PI3K‑AKT‑mTOR pathway in osteoarthritic chondrocytes

Yubiao Zhang, Weisong Cai, Guangtao Han, Siqi Zhou, Jianping Li, Mao Chen, Haohuan Li
Pages: 408-409
Published online on: 11 November 2020

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Correction Open Access

[Corrigendum] Connexin 43 reduces susceptibility to sympathetic atrial fibrillation

Beibei Luo, Yifei Yan, Zhiyu Zeng, Zhengnan Zhang, Haide Liu, Hao Liu, Jinyi Li, Weiqiang Huang, Jiangtao Wu, Yan He
Pages: 410-410
Published online on: 29 October 2020

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Correction Open Access

[Corrigendum] SiRNA‑mediated PIAS1 silencing promotes inflammatory response and leads to injury of cerulein‑stimulated pancreatic acinar cells via regulation of the P38MAPK signaling pathway

Ping Chen, Liya Huang, Yongping Zhang, Minmin Qiao, Yaozong Yuan
Pages: 411-411
Published online on: 30 November 2020

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Journal Cover
January-2026 Volume 57 Issue 1

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

FK506‑binding proteins as emerging bridges linking proteostasis to multi‑system pathogenesis and therapeutic strategies (Review)

Zhi Li, Xiaolei Liu, Hesong Zeng
Article Number: 30
Published online on: 24 November 2025

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Retraction Open Access

[Retracted] Suppression of SIK1 by miR‑141 in human ovarian cancer cell lines and tissues

Jin-Long Chen, Fang Chen, Ting-Ting Zhang, Nai-Fu Liu
Article Number: 29
Published online on: 24 November 2025

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Article Open Access

METTL3 inhibits LINC00312 to suppress osteoporosis progression in a YTHDF2‑dependent manner

Yang Wang, Yihao Tian, Gang Yao
Article Number: 28
Published online on: 20 November 2025

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Review Open Access

Decoding structural birth defects through genomic landscapes: Innovative frameworks for diagnosis (Review)

Ruihao Xu, Haoming Ren, Zhengwei Yuan, Wanqi Huang, Hui Gu
Article Number: 27
Published online on: 20 November 2025

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MOTS‑c protects against placental injury via Nrf2 activation in hypoxia‑induced intrauterine growth restriction mice

Dan Chen, Hui-Min Zhao, Xiao-Lin Sun, Zhi-Xuan Xing, Sheng-Peng Li, Shuai-Chao Li, Ya-Xian Wu, Qing-Feng Pang, Jian-Feng Huang
Article Number: 26
Published online on: 18 November 2025

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Synergistic effects of Akebia saponin D and Semaglutide on diabetic nephropathy and osteoporosis via the Klotho‑p53 signaling axis

Qian Zhang, Dan Wang, Hongxia Jia, Zongji Zheng, Liyan Lin, Linna Li, Ling Wang, Yaoming Xue
Article Number: 25
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑103 modulates tumor progression by targeting KLF7 in non‑small cell lung cancer

Ke Li, Conghu Yuan
Article Number: 24
Published online on: 17 November 2025

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Article

Comparative analysis of pan MHC‑I epitopes immunoreactivity on Hantaan virus nucleocapsid protein

Zhikui Li, Weijie Ding, Yubo Sun, Chenfeng Tian, Shuaishuai Fu, Fei Shi, Zhenchi Fang, Yuanzhe Li, Jianchang Li, Sirui Cai, Haobo Kang, Baozeng Sun, Junqi Zhang, Yuanjie Sun, Shuya Yang, Yusi Zhang, Chunmei Zhang, Yun Zhang, Xiyang Zhang, Kun Yang, Dongbo Jiang
Article Number: 23
Published online on: 14 November 2025

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Human papillomavirus E7 inhibits immune responses in keratinocytes by activating HTRA1‑mediated mitophagy

Boya Zhang, Defeng Kong, Siji Chen, Xuewu Sun, Hao Cheng
Article Number: 22
Published online on: 14 November 2025

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Targeting p38 MAPK signaling pathway: 
Quercetin as a novel therapy for TMJ synovitis

Mosha Cheng, Yuhe Guan, Xiaotao Xin, Xin Yi, Yi Liu
Article Number: 21
Published online on: 13 November 2025

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Review Open Access

Lipid droplets in astrocytes: Key organelles for CNS homeostasis and disease (Review)

Yuchen Wang, Boxuan Wang, Jinchao Hou, Xiaodong Huo, Chenlin Liu, Ruili Guan, Honggang Chen, Yang Zhou, Jianbin Zhang, Congcong Zhuang, Yuankang Zou
Article Number: 20
Published online on: 13 November 2025

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Copper dyshomeostasis and cardiovascular disease: Molecular mechanisms and new strategies for targeted intervention with cuproptosis (Review)

Peiyu Li, Yinghui Li, Qian Meng, Jie Wang, Kun Wang, Sumin Yang
Article Number: 19
Published online on: 13 November 2025

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Elevated FTO alleviates sepsis‑induced acute kidney injury by regulating macrophage inflammatory phenotypes

Xiaona Chen, Ziqi Sun, Jiabo Chen, Jinquan Zhang, Zeyu Liu, Zhengzheng Yan, Quan Li, Zhixia Chen
Article Number: 18
Published online on: 12 November 2025

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Correction Open Access

[Corrigendum]  Suppression of PAX6 promotes cell proliferation and inhibits apoptosis in human retinoblastoma cells

Bo Meng, Yisong Wang, Bin Li
Article Number: 17
Published online on: 10 November 2025

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Review Open Access

Microbial short chain fatty acids: Effective histone deacetylase inhibitors in immune regulation (Review)

Jing Wang, Qin Zhao, Shuwan Zhang, Jia Liu, Xingyue Fan, Bin Han, Yaqin Hou, Xiaopeng Ai
Article Number: 16
Published online on: 05 November 2025

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High‑fat diet and cognitive dysfunction: Mechanistic insights into diet‑induced neurodegeneration (Review)

Min You, Fan Wu, Feng Xiong, Xue-Fei Hu, Huan Wu, Li Zhou, Hong-Xing Zhang
Article Number: 15
Published online on: 05 November 2025

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Article Open Access

ROCK inhibition promotes axon and myelin regeneration via PI3K/Akt/GSK3β in a mouse sciatic nerve injury model

Shuang Dou, Zhijun Li, Boyao Zheng, Zhenyu Ren, Hai Wang, Qing Zuo, Fang Fang, Yuehong Zhuang
Article Number: 14
Published online on: 05 November 2025

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Mechanisms of mTORC1 and GCN2 amino acid sensing pathways in tumorigenesis and metastatic progression (Review)

Chaowei Zhang, Yuxuan Han, Weiyi Yao, Qing Hong, Na Chen
Article Number: 13
Published online on: 04 November 2025

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β‑hydroxybutyric acid as a potential therapeutic metabolite for type 2 diabetes mellitus (Review)

Xianyi Ding, Jiabin Wu, Lian Wang, Ke Li, Haoyang Gao, Mingyu Wu, Qiuyu Zhang, Ruonan Han, Wenhong Wang, Weihua Xiao
Article Number: 12
Published online on: 03 November 2025

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Review

Histone lactylation: Unveiling a novel pathway for the impact of lactate on physiological and pathological processes (Review)

Xunjie Jian, Chang Cheng, Wenjie Lu, Hui Peng, Diqi Yang
Article Number: 11
Published online on: 03 November 2025

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Interpretation of the molecular mechanism and therapeutic potential of microRNA‑155 in cardiovascular and cerebrovascular diseases (Review)

Xitong Zhao, Pengqin Wang
Article Number: 10
Published online on: 03 November 2025

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Expression of Concern Open Access

[Expression of Concern]  CDKN2A (p16INK4A) affects the anti‑tumor effect of CDK inhibitor in somatotroph adenomas

Yiyuan Chen, Zhenye Li, Qiuyue Fang, Hongyun Wang, Chuzhong Li, Hua Gao, Yazhuo Zhang
Article Number: 9
Published online on: 29 October 2025

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TWEAK modulates the characteristics of periodontal ligament stem cells via the Fn14/NF‑κB pathway

Linlin Xiao, Man Qu, Lulu Chen, Mingli Xiang, Qian Long, Jianguo Liu, Xiaoyan Guan, Chengcheng Liao
Article Number: 8
Published online on: 27 October 2025

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Harnessing copper: Innovative approaches to combat neurodegenerative diseases and cancer (Review)

Tao Duan, Hanhai Mao, Xingyue Jiang, Ying Tian, Jidong Zhang, Jun Tan
Article Number: 7
Published online on: 27 October 2025

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Retraction Open Access

[Retracted] Effects of miR‑106b‑3p on cell proliferation and epithelial‑mesenchymal transition, and targeting of ZNRF3 in esophageal squamous cell carcinoma

Guanen Qiao, Chenguang Dai, Yang He, Junjie Shi, Chunfang Xu
Article Number: 6
Published online on: 27 October 2025

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Review Open Access

Immune and metabolic remodeling following bariatric surgery: Implications for targeted immunotherapy (Review)

Yiming Shao, Ke Song, Ruixin Yu, He Xiao, Chengjun Li, Yuling Deng, Yuan Zhang, Yixing Ren
Article Number: 5
Published online on: 24 October 2025

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Exportin 1 inhibitor KPT‑330 reverses oxaliplatin resistance via p53 nuclear retention in colorectal cancer

Chuanxi Lai, Xiya Jia, Yiyi Chen, Kangke Chen, Fei Wang, Qiqi Zhang, Xiaonan Xiang, Zhe-Sheng Chen, Lingna Xu, Sheng Dai
Article Number: 4
Published online on: 23 October 2025

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Targeting of CIRP attenuates osteoarthritis progression via suppressing TLR4/NF‑κB/NLRP3 signaling axis

Weichao Sun, Yi Liao, Jianguo Feng, Jianhui Liang, Qifei He, Yinxing Cui, Dixi Huang, Houyin Shi, Wei You, Wei Sun, Qian Yi
Article Number: 3
Published online on: 23 October 2025

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Review

Importance of B cells (Review)

Zhiyuan Liu, Haoran Dai, Xiaoyu Cui, Yeping Liu, Zhaocheng Dong
Article Number: 2
Published online on: 22 October 2025

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Retraction Open Access

[Retracted] Hypoxic preconditioned bone mesenchymal stem cells ameliorate spinal cord injury in rats via improved survival and migration

Weiheng Wang, Xiaodong Huang, Wenbo Lin, Yuanyuan Qiu, Yunfei He, Jiangming Yu, Yanhai Xi, Xiaojian Ye
Article Number: 1
Published online on: 22 October 2025

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February-2026 Volume 57 Issue 2

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

FGF4 alleviates the lung cell damage caused by high glucose via AMPK‑PGC‑1 signaling axis in vitro and in vivo

Qiujuan Fu, Yongfang Ou, Qin Wu, Jue Gong, Feixia Li, Tuxing Wang, Zhitai Lin, Kejie Huang, Jianlong Xie
Article Number: 39
Published online on: 05 December 2025

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STOML2 interacts with PHB to activate the MEK/ERK signaling pathway and mediates autophagy‑related proteins in the progression of hepatocellular carcinoma

Haoyang Hu, Haozhe Zhang, Shuai Han, Jianli Chen, Ying Xie
Article Number: 38
Published online on: 04 December 2025

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HMGB1 mediates low-dose ionizing radiation-induced Wnt/β-catenin activation in SRA01/04 cells: Mechanistic clues to early cataractogenesis

Ping Wang, Chunnan Piao, Dong Yan, Yingxue He, Yaru Li, Li Fan, Mei Tian
Article Number: 37
Published online on: 04 December 2025

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FBXO22 promotes hepatocellular carcinoma progression via paracrine myo‑inositol‑induced M2‑type polarization of macrophages

Liangliang Bai, Jing Xiong, Sihai Chen, Jiahao Hu, Meixia Zhang, Bimin Li, Jing Hu, Mingyan He
Article Number: 36
Published online on: 02 December 2025

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Branched‑chain amino acid metabolism and bone metabolism: Implications for osteoporosis pathogenesis and therapeutic strategies (Review)

Qi Xiao, Haimin Zeng, Ruhui Yang, Yuxin Zhan, Fangzhen Lin, Bofan Chen, Xiang Chen
Article Number: 35
Published online on: 02 December 2025

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Mitochondria-associated endoplasmic reticulum membranes: Emerging regulators of cardiac microvascular ischemia/reperfusion injury (Review)

Yan Wang, Baowei Feng, Yanting Wu, Zongle Sun, Hao Yuan, Wei Chen, Chang Zhao, Zhi Liu
Article Number: 34
Published online on: 02 December 2025

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Role of matrix metalloproteinases in the invasion of glioblastoma and drug interventions (Review)

Bohao Zheng, Ying Han, Haiying Zhang
Article Number: 33
Published online on: 01 December 2025

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Review

Bridging bench to bedside: Exosome‑based strategies for endometriosis diagnosis and treatment (Review)

Wanmeng Chen, Yujiu Ma, Xudong Zhang, Siwen Zhang, Shanshan Wu, Yimeng Lu, Jichun Tan
Article Number: 32
Published online on: 01 December 2025

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Retraction Open Access

[Retracted] miR‑381 functions as a tumor suppressor by targeting ETS1 in pancreatic cancer

Guanen Qiao, Jing Li, Jun Wang, Zhaoyang Wang, Wei Bian
Article Number: 31
Published online on: 01 December 2025

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