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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
September-2025 Volume 30 Issue 3

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Association of recurrence with patient and tumor factors in gastrointestinal stromal tumors of small intestine: A single‑institutional retrospective study

Yuri Nishioka, Yasunori Matsumoto, Gaku Ohira, Koichi Hayano, Toru Tochigi, Tetsuro Maruyama, Yoshihiro Kurata, Ryota Otsuka, Koichiro Okada, Atsushi Hirata, Michihiro Maruyama, Hisahiro Matsubara
Article Number: 447
Published online on: 17 July 2025

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Article Open Access

circEFR3A promotes breast cancer progression by sponging miR‑590‑3p to upregulate androgen receptor expression

Yunzhe Mi, Xinle Wang, Han Song, Zhenyu Wu, Sainan Li, Fei Liu, Wei Liu, Meixiang Sang, Cuizhi Geng
Article Number: 446
Published online on: 17 July 2025

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Effect of TP53 mutation, expression and polymorphism on the survival, immune infiltration and ferroptosis in patients with prostate cancer

Gui-Min Wen, Zhen-Ying Zhao, Xiao-Hui Zheng, Da-Hua Liu, Pu Xia
Article Number: 445
Published online on: 17 July 2025

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Article Open Access

Proteomics analysis reveals elevated RAB21 in serum‑derived extracellular vesicles from patients with follicular thyroid carcinoma

Kyojiro Kawakami, Naoki Edo, Koji Morita, Toshio Ishikawa, Hiroyuki Onose, Tatsuya Fukumori, Hiroki Tsumoto, Keitaro Umezawa, Masafumi Ito, Yuri Miura
Article Number: 444
Published online on: 16 July 2025

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Article Open Access

Risk score model with two immune infiltration‑related long non‑coding RNAs to predict prognosis in patients with osteosarcoma

Ling-Rong Zeng, Guang-Hui Zhu, Hai-Bo Mei, Ge Yang
Article Number: 443
Published online on: 15 July 2025

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Review Open Access

N6‑methyladenosine in cervical carcinogenesis: Mechanistic insights and therapeutic perspectives (Review)

Man Xu, Fanglei Yang, Huan Chen, Feiyun Jiang
Article Number: 442
Published online on: 14 July 2025

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Retraction Open Access

[Retracted] Effects of TLR4 gene silencing on the proliferation and apotosis of hepatocarcinoma HEPG2 cells

Yating Liu, Tao Li, Yuanhong Xu, Enjun Xu, Min Zhou, Baolong Wang, Jilong Shen
Article Number: 441
Published online on: 14 July 2025

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Article Open Access

CIAO1 as a crucial signature gene of cuproptosis in gastric cancer

Jiaying Qu, Chunhui Yang, Shunchen Zhou, Bosen Zhao, Qiangsong Tong, Liduan Zheng
Article Number: 440
Published online on: 14 July 2025

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Case Report Open Access

Prolonged survival of a case with three different malignancies - cutaneous malignant melanoma, gastrointestinal stromal tumor and thyroid papillary cancer: A case report

Hülya Odabaşi Bükün, Erdem Çubukçu, Ahmet Bi̇lgehan Şahi̇n, Şaduman Balaban Adim
Article Number: 439
Published online on: 14 July 2025

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Article Open Access

Analysis and exploration of the association between serum tumor marker status and clinical pathological features, as well as efficacy, in colorectal cancer

Zhenzhu Xing, Yifan Xiao, Shaobing Li, Gang Jia, Peng Cheng, Yuming Chen, Jianwei Zhou, Liang Sun, Chuangxin Lu
Article Number: 438
Published online on: 09 July 2025

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Article Open Access

Hepatic artery infusion chemotherapy combined with lenvatinib and PD‑1 inhibitors in the treatment of intermediate and advanced unresectable hepatocellular carcinoma

Peng Jiang, Fengfeng Li, Zhenyu Jiang, Yiling Sun, Fan Yang, Lisha Chu, Ya Gai, Hongjian Wang
Article Number: 437
Published online on: 09 July 2025

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Article Open Access

A novel defined manganese metabolism‑related gene signature for predicting the prognosis of pancreatic ductal adenocarcinoma

Zichao Xiong, Zhen Zhang, Shaodan Cheng, Shaohua Liao
Article Number: 436
Published online on: 09 July 2025

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Article

Usefulness of the preoperative Prognostic Immune and Nutritional Index as a prognostic predictor for patients with gastric cancer

Jinquan Li, Li Yu, Xiaosheng Hu, Tao Huang, Mingmin Chen, Shanzhong Zhang
Article Number: 435
Published online on: 08 July 2025

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Review Open Access

Research progress of anti‑angiogenic therapy combined with immunotherapy and radiotherapy for the treatment of brain metastases in non‑small cell lung cancer (Review)

Man Li, Jingyan Gao, Fei Lu, Chengshu Gong, Jie Zhang, Li Wang, Yaoxiong Xia
Article Number: 434
Published online on: 08 July 2025

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Article Open Access

Morphological, immunophenotypic and neuroradiological characteristics of primitive B‑large cell diffuse lymphoma of the central nervous system: A retrospective cohort analysis

Ida Rizzuto, Cristina Pizzimenti, Vincenzo Fiorentino, Sarah Caroline Scarcella, Maurizio Martini, Francesca Granata, Antonino Germanò, Antonio Ieni, Giovanni Tuccari
Article Number: 433
Published online on: 08 July 2025

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Case Report Open Access

Alectinib efficacy in advanced lung adenocarcinoma with coexistence of a novel ALK-MTUS2 and STRN3-ALK double fusion: A case report and literature review

Xirui Qiu, Yu Wei, Xiaoxiao Wang, Siyan Xu, Yaru Zhang, Hailang He, Xianmei Zhou
Article Number: 432
Published online on: 07 July 2025

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Article Open Access

Predicting pathological staging of non‑small cell lung cancer using a multi‑task radiomics model integrating intratumoral and peritumoral features

Ruonan Pan, Xiaoqian Lu, Xin Dong, Liang Guo, Xiang Li, Dianbo Cao
Article Number: 431
Published online on: 07 July 2025

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Retraction Open Access

[Retracted] circ_103809 promotes breast cancer progression by regulating the PI3K/AKT signaling pathway

Xiaoli Qiu, Qinghua Wang, Huiping Song, Di Shao, Jie Xue
Article Number: 430
Published online on: 07 July 2025

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Article Open Access

Risk factors for bone metastasis in lung cancer and the efficacy of palliative radiotherapy and opioid analgesics in alleviating bone metastasis pain

Qinzhi Zhang, Bo Qu, Jiazhen Fan, Chunyu Liu, Bin Shan, Chunrong Chen, Yue Gao
Article Number: 429
Published online on: 07 July 2025

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Article

The usefulness of immunonutrition in chemotherapy and chemoradiotherapy for esophageal cancer

Satomi Araki, Takuya Araki, Naritaka Tanaka, Makoto Sakai, Ayumu Nagamine, Daisuke Nagano, Hideaki Yashima, Hiroshi Saeki, Hiroyuki Kuwano, Koujirou Yamamoto
Article Number: 428
Published online on: 07 July 2025

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Article Open Access

Clinical importance of E‑cadherin deficiency in resectable gastric cancer: A nested case‑control study

Cheng Zheng, Min Dai, Dongying Wang, Xingchen Liu, Zhiyi Xiang, Anyi Xu, Ping Chen, Feng Wu, Yuan Yuan, Shengqiang Ji, Lihu Gu
Article Number: 427
Published online on: 04 July 2025

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Article Open Access

Silymarin induces multiple myeloma cell apoptosis by inhibiting the JAK2/STAT3 signaling pathway

Haiyun Liu, Tingting Liu, Junquan Zeng, Quangang Fang
Article Number: 426
Published online on: 04 July 2025

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Case Report Open Access

Bronchial granular cell tumor incidentally detected during preoperative evaluation of thyroid carcinoma: A case report

Biao Wang, Guozhu Liu, Baolu Liu, Rushuai Hou, Cuiping Li, Mengjie Li, Jian Zhu
Article Number: 425
Published online on: 03 July 2025

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Review Open Access

Novel therapeutic strategies for non‑small cell lung cancer: Combination therapies with immune checkpoint inhibitors (Review)

Shengyao Ma, Ruixin Hu, Xiaobin Xue, Meihua Qu, Guoping Sun
Article Number: 424
Published online on: 03 July 2025

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Review Open Access

Research progress on evaluation methods for skeletal muscle mass assessment in sarcopenia (Review)

Wei Wu, Min Liu, Qin Zeng, Chenyi Tang, Jiaqi Huo
Article Number: 423
Published online on: 03 July 2025

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Case Report Open Access

A FANCD2 gene mutation case analysis providing potential insights into the molecular mechanisms of gastric adenocarcinoma: A case report

Kexin Zheng, Fengying Du, Yaodong Sang, Kangdi Dong, Kun Xiao, Ronghua Zhang, Changqing Jing, Liang Shang, Leping Li
Article Number: 422
Published online on: 03 July 2025

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Review

Histone lactylation: A new frontier in laryngeal cancer research (Review)

Qiaoling Tong, Chunsheng Huang, Qizhen Tong, Zhiyu Zhang
Article Number: 421
Published online on: 02 July 2025

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Case Report

Elective arteriovenous fistula ligation for prevention of lymphedema in a patient with breast cancer before ipsilateral axillary lymph node dissection: A case report

Kamil Szemik, Karolina Pańczyk, Klaudia Jurkowska, Weronika Bulska‑Będkowska, Aureliusz Kolonko, Jerzy Chudek
Article Number: 420
Published online on: 02 July 2025

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Article Open Access

Transcriptomic analyses unveil the mechanism of saikosaponin A in inhibiting human neuroblastoma SK‑N‑AS cells

Ning Gao, Jialin Sun, Wei Zhao, Lihui Duan, Hongyao Cai, Bo Liu, Yupeng Cheng
Article Number: 419
Published online on: 02 July 2025

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Review Open Access

Functions and mechanisms of long non‑coding RNA in esophageal squamous cell carcinoma (Review)

Yuning Lin, Zhenyi Lv, Hongyan Xie, Wenzhen Zhao, Ruonan Pu, Zhongying Zhang, Hongwei Jin
Article Number: 418
Published online on: 01 July 2025

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Case Report Open Access

Splenic infarction secondary to multi‑site thrombosis in lung adenocarcinoma with EGFR‑L858R mutation: A case report

Qingsong Wang, He Zheng, Mingpu Wang, Xiaoyu Wei, Yuzhen Ma, Zhengqiang Wan
Article Number: 417
Published online on: 01 July 2025

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Retraction Open Access

[Retracted] MEG‑3‑mediated Wnt/β‑catenin signaling pathway controls the inhibition of tunicamycin‑mediated viability in glioblastoma

Xiangyu Cui, Dezhou Sun, Bin Shen, Xin Wang
Article Number: 416
Published online on: 30 June 2025

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Review Open Access

Application of respiratory motion management technology for patients with lung cancer treated with stereotactic body radiotherapy (Review)

Kainan Shao, Weijun Chen, Yaping Xu, Shuangyan Yang
Article Number: 415
Published online on: 27 June 2025

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Article Open Access

Prognostic predictive value of the preoperative systemic immunoinflammatory index combined with the neutrophil‑to‑lymphocyte ratio in patients with primary liver cancer undergoing transarterial chemoembolization

Maoyuan Zhang, Kunlong Yang, Jiyun Zhang, Tingting Mo, Yijing Chen, Chuwen Zhong, Sihao Chen, Jingtong Zhang, Min Ye, Ting Zhou, Chunmei Chen, Qiao Chen
Article Number: 414
Published online on: 27 June 2025

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Article Open Access

Differential extracellular matrix proteomic signatures in colorectal tumors from Appalachian and non‑Appalachian patients

Alexander T. Sougiannis, Harrison B. Taylor, Stephen C. Zambrzycki, Lindsey Conroy, Rachel Strubler, Christin Edge, Richard R. Drake, Kristin Wallace, Derek Allison, Eun Lee, Ramon C. Sun, Peggi M. Angel
Article Number: 413
Published online on: 26 June 2025

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Article Open Access

Axillary fat metastasis in breast cancer: A case report

Shilong Zhang, Juan Chen, Yan Zhang, Zhangbo Xu, Jiechao Ren, Siyang Huang, Zhujuan Wu, Jian Wu
Article Number: 412
Published online on: 26 June 2025

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Correction Open Access

[Corrigendum] The impact of metformin and salinomycin on transforming growth factor β‑induced epithelial‑to‑mesenchymal transition in non‑small cell lung cancer cell lines

Stefan Koeck, Arno Amann, Julia M. Huber, Gabriele Gamerith, Wolfgang Hilbe, Heinz Zwierzina
Article Number: 411
Published online on: 25 June 2025

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Case Report Open Access

Concomitant T315I and E459K mutations in chronic myeloid leukemia: A case report

Xin Zhou, Shi-Ting Huang, Ning-Ning Shan
Article Number: 410
Published online on: 24 June 2025

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Article Open Access

BLID is a drug-responsive target of FOXO3a and multi-omics analysis reveals survival mechanisms and therapeutic vulnerabilities in BLID-deficient breast cancer cells

Sivaramakrishna Yadavalli, Rong Hu, Antonina Rait, Rency Varghese, James Li, Ofer Eidelman, Xiaojun Zou, Habtom Ressom, Esther Chang, Meera Srivastava, Robert Clarke, Usha Kasid
Article Number: 409
Published online on: 24 June 2025

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Case Report Open Access

Radical treatment for metastasis of HER2‑positive rectal adenocarcinoma to the liver: A case report and literature review

Jiandi Huang, Zhiru Li, Dongwei He, Xin Li, Yaping Wang, Qingxia Li, Dongmiao Wang, Xiaoyan Fan
Article Number: 408
Published online on: 24 June 2025

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Article Open Access

Diagnostic performance of contrast‑enhanced ultrasound vs. conventional ultrasound for lymph node metastasis in patients with thyroid cancer: A meta‑analysis

Junhui Gao, Ying Liu, Lipeng Zheng, Xiaogang Wang, Yingluan Wang, Tongxia Zhou
Article Number: 407
Published online on: 24 June 2025

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Article Open Access

Post‑irradiation mastoid mucosa disease in patients with nasopharyngeal carcinoma after radiotherapy: A large‑cohort and long‑term study

Rui-Ling Xie, Si-Yuan Chen, Zheng-Kai Feng, Shao-Yan Feng, Peng Hua, Wen-Bin Wu, Xiao-Tong Duan, Chong-Yang Duan, Chao Lin, Bo Lv, Jin-Hui Wu, Rui You, Wei-Hua Jia, Ming-Yuan Chen, You-Ping Liu
Article Number: 406
Published online on: 23 June 2025

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Article Open Access

Evidence of a functional Smad2/3 signaling axis and TGFβ‑mediated autocrine transcriptional regulation of in vitro vasculogenic mimicry in mesenchymal stem/stromal cells

Kaénon Prisca‑Desiré Gnao, Marie-Eve Roy, Alain Zgheib, Michel Desjarlais, Borhane Annabi
Article Number: 405
Published online on: 23 June 2025

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Retraction Open Access

[Retracted] tRNA‑derived fragment tRF‑Glu49 inhibits cell proliferation, migration and invasion in cervical cancer by targeting FGL1

Yang Wang, Wenying Xia, Fangrong Shen, Jinhua Zhou, Yanzheng Gu, Youguo Chen
Article Number: 404
Published online on: 23 June 2025

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Article Open Access

A novel glutamine metabolism‑related risk model for prognostic prediction of liver hepatocellular carcinoma

Xia He, Rui Wang, Yonghua Zhu, Xi Chen, Yu Zhang, Min Sun
Article Number: 403
Published online on: 20 June 2025

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Journal Cover
June-2026 Volume 31 Issue 6

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Early postoperative complications and patient‑reported quality of life following breast‑conserving surgery with intraoperative radiotherapy: A prospective cohort study

Hongmei Han, Xuwen Liu, Baozhong Zhang, Jingjing Liu, Jing Wang, Qingsong Pang
Article Number: 268
Published online on: 27 April 2026

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Exploring the mechanism of action of glaucocalyxin D against acute myeloid leukemia using network pharmacology, molecular docking and cellular experiments

Lian Chen, Weixian Yang, Weiqing Zhang, Heng Luo, Chen Yan
Article Number: 267
Published online on: 27 April 2026

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Review
Special Issue

Advances in cerebrospinal fluid biomarkers for the diagnosis, treatment and monitoring of leptomeningeal metastases (Review)

Huaixu Li, Wenwen Fan, Fengchun Mu, Cheng Fang, Ting Xiao, Jinghai Wan, Hongqing Cai
Article Number: 266
Published online on: 27 April 2026

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Article Open Access

Exploration of the effect and mechanism of Eclipta prostrata L. against gastric cancer based on network pharmacology and experimental verification

Weizhou Yu, Xiaohui Ni, Jing Wang, Wei Xia, Xinya Shen, Fan Qiu, Yuping Chen
Article Number: 265
Published online on: 27 April 2026

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Article Open Access

Neoadjuvant radiotherapy for resectable hepatocellular carcinoma with vascular invasion: A systematic review and meta‑analysis

Yuhao Su, Yuxin Liang, Deyuan Zhong, Hongtao Yan, Qinyan Yang, Xiaolun Huang
Article Number: 264
Published online on: 27 April 2026

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Article Open Access

Computational discovery of novel colony‑stimulating factor‑1 receptor as a potential therapeutic biomarker in osteosarcoma and a novel inhibitor from herbal sources

Hui Zhang, Shiwei Wu, Dan Luo, Jincai Guo
Article Number: 263
Published online on: 24 April 2026

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Article Open Access

Effect of the use of hormonal replacement therapy on breast cancer prognosis: A systematic review and meta‑analysis

Javier Angel Canelas Fernández, Jéssica Alonso‑molero, Paz Rodríguez‑cundín, Javier Llorca, Inés Gómez‑aceb, Trinidad Dierssen‑sotos
Article Number: 262
Published online on: 24 April 2026

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Article Open Access

Evaluation of smoking status as a prognostic factor under immune checkpoint inhibitor treatment: A single center analysis

Christoph Schaefers, Annika Poch, Anika Forstreuter, Frederike Bokemeyer, Carsten Bokemeyer, Christoph Seidel
Article Number: 261
Published online on: 24 April 2026

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Correction Open Access

[Corrigendum] CDDO, a PPAR‑γ ligand, inhibits TPA‑induced cell migration and invasion through a PPAR‑γ‑independent mechanism

Hye-Yeon Jang, On-Yu Hong, Hyun Jo Youn, Jaeuk Jung, Eun Yong Chung, Sung Hoo Jung, Jong-Suk Kim
Article Number: 260
Published online on: 24 April 2026

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Review Open Access

Dual roles of neutrophil extracellular traps in tumors: From pro‑metastatic mechanisms to immunotherapeutic strategies (Review)

Mingxin Guo, Han Wang, Jiaqi Zeng, Ning Wu, Zhiqiang Hu, Ao Xue, Ting Dai
Article Number: 259
Published online on: 23 April 2026

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Review Open Access

Emerging role of protein arginine methyltransferase 5 in gastrointestinal cancer (Review)

Rui Zhang, Yiwen Lu, Xiaohua Fang, Fengquan Zhang, Weidong Wu, Jie Song, Zhenzhen Liang
Article Number: 258
Published online on: 23 April 2026

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Case Report Open Access

Adjuvant immunotherapy plus chemotherapy and maintenance immunotherapy for pulmonary lymphoepithelioma‑like carcinoma with hepatitis B virus infection, KRAS mutation and high expression of programmed death ligand 1: A case report

Jing Zhu, Qing-Gui Xu, Jiao Zhu, Rui-Xiang Zhou, Yu-Chuan Zhou, Zhi-Ke Li
Article Number: 257
Published online on: 22 April 2026

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Retraction Open Access

[Retracted] Interleukin‑17 promotes the development of cisplatin resistance in colorectal cancer

Guolong Sui, Yingna Qiu, Haijuan Yu, Qingbin Kong, Baowen Zhen
Article Number: 256
Published online on: 22 April 2026

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Article Open Access

An m6A‑programmed cell death signature predicts prognosis and identifies STK25 as a therapeutic target in colon adenocarcinoma

Hezhi Yu, Tihui Li, Xiaoyun Huang, Zihan Chen, Zixiang Lin, Fenglin Chen
Article Number: 255
Published online on: 22 April 2026

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Article Open Access

METTL5 reprograms glycolytic metabolism and promotes non‑small cell lung cancer progression by modifying PGAM1

Yuchen Shan, Xiaoyu Duan, Kai Yuan, Ming Lou, Qiyong Wu, Zhaojia Gao
Article Number: 254
Published online on: 20 April 2026

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Article Open Access

Clinical features and outcomes of peripheral T‑cell lymphoma, not otherwise specified: A single institution retrospective analysis of 30 cases

Meng-Xue Ma, Ya-Li Zhang, Li-Na Xing, Qiu-Yi Wang, Shukai Qiao
Article Number: 253
Published online on: 20 April 2026

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Article Open Access

BUD23 is associated with malignancy and correlates with immune infiltration in NSCLC

Yonghuang Tan, Jun Ma, Jiangli Zhou, Jianjun Lu
Article Number: 252
Published online on: 20 April 2026

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Article Open Access

Evaluation of NID2 and CDO1 methylation for ovarian cancer screening

Shuilian Wu, Jing Jin, Yuanyuan Cao, Xiaofan He, Qiang Hou, Mingfeng Jiang
Article Number: 251
Published online on: 20 April 2026

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Retraction Open Access

[Retracted] Improved ataxia telangiectasia mutated kinase inhibitor KU60019 provides a promising treatment strategy for non‑invasive breast cancer

Ying Zhu, Changfei Mao, Jianzhong Wu, Shuchun Li, Rong Ma, Haixia Cao, Minghua Ji, Changwen Jing, Jinhai Tang
Article Number: 250
Published online on: 20 April 2026

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Case Report Open Access

Fever and leukemoid reaction in bladder cancer: A case report

Tianrun Huang, Jiguo Xu, Yuwei He, Yu Shen, Chenlong Chu, Jingyuan Lu, Parehe Alimu, Chunlei Chen, Jianhe Liu
Article Number: 249
Published online on: 20 April 2026

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Article Open Access

Prognostic effect and prognostic factors of TACE for the treatment of unresectable hepatocellular carcinoma: Propensity score matching analysis

Liangliang Zhang, Cancan Li, Hui Guo, Xue Zhang, Wei Liu, Xing Xu
Article Number: 248
Published online on: 16 April 2026

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Expression of Concern Open Access

[Expression of Concern] Long non‑coding RNA BX357664 inhibits cell proliferation and metastasis in human lung cancer

Shu-Hui Xiao, Gong-Xiang Li, Lingli Quan
Article Number: 247
Published online on: 16 April 2026

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Article

Safety and feasibility of total neoadjuvant FLOT chemotherapy in locally‑advanced gastric and gastroesophageal junction cancer

Oleksii Dobrzhanskyi, Andrii Horodetskyi, Mykyta Pepenin, Yurii Kondratskyi
Article Number: 246
Published online on: 16 April 2026

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Article Open Access

Vasculogenic mimicry and breast cancer prognosis: Insights into predictive model development

Zhifeng Wu, Yueyue Teng, Shengchao Huang, Shiming Shi, Pu Qiu, Leyao Shan, Meihua Lin, Yuanqi Zhang
Article Number: 245
Published online on: 15 April 2026

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Article Open Access

Effect and safety analysis of raltitrexed peritoneal perfusion in patients with intermediate and advanced colorectal cancer

Yanhua Wan, Xiaoyun Dai, Liang Chao
Article Number: 244
Published online on: 15 April 2026

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Article Open Access

Mechanism of action of alkaloids in Fritillaria‑induced autophagy and apoptosis in non‑small cell lung cancer

Mengru Teng, Mengrui Zhang, Jun He, Wai Ming Tse, Kathy Wai Gaun Tse, Chengwu Liu, Bengui Ye
Article Number: 243
Published online on: 15 April 2026

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Article Open Access

Identification of a prognostic model using immune related genes combined with tumour mutational burden and T cell infiltration in triple‑negative breast cancer

You Meng, Ze-Xin Han, Jie Zhu, Ying Wang, Yue-Qing Huang, Zhong-Hua Zou, Yu-Yuan Ma, Yi-Fan Li, Han Wang, Ying Li, Lian Lian, Wen-Jie Wang
Article Number: 242
Published online on: 15 April 2026

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Correction Open Access

[Corrigendum] Silencing glioma‑associated oncogene homolog 1 suppresses the migration and invasion of hepatocellular carcinoma in vitro

Zeming Hu, Fangfang Xie, Ang Hu, Mengjing Xu, Yuwen Liu, Jiankang Zhang, Jianbo Xiao, Yunlei Song, Jianing Zhong, Bin Chen
Article Number: 241
Published online on: 15 April 2026

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Article

A novel inflammation and tumor marker‑based prognostic score, neutrophil‑lymphocyte ratio‑C‑reactive protein‑Ca19‑9, in metastatic gastric cancer

Berkan Karabuğa, Osman Bilge Kaya, Ekin Konca Karabuğa, Ergin Aydemir, Mehmet Emin Yilmaz, Sedef Tatar Bolat, Ayşegül Uçkun, Enes Kaptan, Öztürk Ateş, Mustafa Büyükkör
Article Number: 240
Published online on: 15 April 2026

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Article Open Access

KRAS (G12D)‑selective inhibitor MRTX1133 suppresses proliferation and differentially modulates chemosensitivity in ovarian mucinous carcinoma

Ryota Watano, Hiroaki Mizukami, Yasushi Saga
Article Number: 239
Published online on: 15 April 2026

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Article

Intensity‑ and time‑dependent anticancer effects of alternating electric fields in non‑small cell lung cancer cell lines

Jinju Heo, Myonggeun Yoon
Article Number: 238
Published online on: 15 April 2026

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Review Open Access

KLF family of proteins in gastrointestinal tumors (Review)

Jingjing Zhang, Rupu Zhao, Pengjie Yang, Yong Zhu, Benben Zhu
Article Number: 237
Published online on: 15 April 2026

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Article

Establishment and validation of a diagnostic model for evaluating synchronous liver metastasis in pancreatic cancer using comprehensive blood biochemical indicators

Yiyi Jiang, Gaoyao Peng, Songqing He, Jiangfa Li
Article Number: 236
Published online on: 14 April 2026

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Review Open Access

Soluble isoforms of EGFR family in breast cancer: Advances and clinical relevance (Review)

Peng Yang, Xinnong Jiang, Fangguo He
Article Number: 235
Published online on: 14 April 2026

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Article Open Access

Thrombospondin‑1 triggers calreticulin expression in human mucoepidermoid carcinoma MC‑3 cells via the PERK/CHOP pathway

Shengwei Bao, Yuanyuan Zhu, Lijuan Guo, Sen Yang
Article Number: 234
Published online on: 14 April 2026

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Article Open Access

Unveiling the prognostic and immunotherapeutic role of Tregs in lung cancer using integrated analysis of single‑cell and bulk RNA‑sequencing

Hongwei He, Zhiming Xiao, Jijun Xue, Yu Zhang, Jichen Qu, Peng Wu, Qiangjun He
Article Number: 233
Published online on: 14 April 2026

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Review Open Access

Nobiletin in cancer therapy: Emerging insights into multi-target mechanisms, overcoming drug resistance and therapeutic translation (Review)

Yanfang Zhang, Qingcai Li, Wenbin Yu, Bin He, Jiahua Peng, Bin Yao
Article Number: 232
Published online on: 14 April 2026

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Expression of Concern Open Access

[Expression of Concern] Apoptotic effect of gambogic acid in esophageal squamous cell carcinoma cells via suppression of the NF‑κB pathway

Wen-Yue Liu, Xu Wu, Cheng-Quan Liao, Jie Shen, Jun Li
Article Number: 231
Published online on: 14 April 2026

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Article

Pretreatment C‑reactive protein‑triglyceride‑glucose index predicts survival in patients with FLOT‑treated locally advanced gastric and gastroesophageal junction cancer

Ayşegül Dumludağ, Mehmet Torun, Osman Sütçüoğlu
Article Number: 230
Published online on: 09 April 2026

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Case Report

Intravascular large B‑cell lymphoma mimicking an orbital mass lesion and bilateral cavernous sinus syndrome: A case report

Qiong Wu, Yiran Jia, Bentao Yang, Xiaojin He, Hongjuan Liu, Libin Jiang
Article Number: 229
Published online on: 09 April 2026

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Correction Open Access

[Corrigendum] FXR1 promotes proliferation, invasion and migration of hepatocellular carcinoma in vitro and in vivo

Kun Zhao, Jie Gao, Jihua Shi, Chengcheng Shi, Chun Pang, Jie Li, Wenzhi Guo, Shuijun Zhang
Article Number: 228
Published online on: 09 April 2026

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Article Open Access

Role of CDX2 in the prognosis of colorectal cancer across stages 0‑IV

Guojun Tong, Hai Qian, Yuefeng Fei, Sheng Yu, Kun Guo, Wenwen Yu, Jing Li, Sicheng Yan
Article Number: 227
Published online on: 08 April 2026

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Article Open Access

Exploring multiple biomarkers and constructing ferroptosis‑associated competing endogenous RNA networks as dual targets in retinoblastoma

Zhengjia Kang, Gaoqin Liu
Article Number: 226
Published online on: 08 April 2026

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Review Open Access

Role of mesenchymal stem cells and their derived exosomes in cervical cancer: Bidirectional mechanisms and research progress (Review)

Xue Li, Daqing Wang
Article Number: 225
Published online on: 08 April 2026

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Review Open Access

Hypoxia‑inducible factors: Regulatory functions and status as a therapeutic target in gastric cancer (Review)

Jia Xu, Guangzhi Ding, Yiming Wang, Chang Liu
Article Number: 224
Published online on: 08 April 2026

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Article Open Access

Machine learning‑based programmed cell death gene signature for prognosis and drug sensitivity in breast cancer

Nan Wu, Zhongting Fan
Article Number: 223
Published online on: 08 April 2026

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Article Open Access

Assessing the density of lymph node metastasis in various inguinal regions of penile cancer using the nine‑section method: A prospective study

Chen Hu, Longguo Dai, Hongyi Wu, Yu Bai, Jun Li, Haiyang Jiang, Haoli Yin, Ying Bi, Wenzhao Wu, Ruiqian Li, Hong Shi
Article Number: 222
Published online on: 08 April 2026

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Article Open Access

Overexpression and knockdown of 5‑lipoxygenase regulates the migration and invasion of colorectal cancer cells

Xuyang Li, Jiletu Huge, Xiaoling Wang, Jing Zhou, Xiudan Li, Xiaoyan Gao, Tiewei Shi, Chunying Bai
Article Number: 221
Published online on: 08 April 2026

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Case Report

Targeting TROP‑2 in treatment‑resistant non‑small cell lung cancer harboring the KRAS G12C mutation and TROP‑2 upregulation: A case report

Lu Sun, Ying Xiong, Xiaobing Li, Yi Peng
Article Number: 220
Published online on: 08 April 2026

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Article Open Access

Exosomal‑miR‑32‑5p directly targets FOXN2 to regulate the proliferation, migration and apoptosis of uterine corpus endometrial carcinoma via the PI3K/AKT/BCL‑2 pathway

Xin Chen, Huihui Li, Xiang Cheng, Yirong Cai, Guangyi Guo
Article Number: 219
Published online on: 08 April 2026

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Expression of Concern Open Access

[Expression of Concern] PRKACB is downregulated in non‑small cell lung cancer and exogenous PRKACB inhibits proliferation and invasion of LTEP‑A2 cells

Yong Chen, Ying Gao, Ye Tian, Da-Li Tian
Article Number: 218
Published online on: 07 April 2026

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Review Open Access

Lactylation enzymes in cancer: Mechanisms and novel therapeutic approaches (Review)

Guiyang Tang, Hanrong Zuo, Rou Long, Chaohui Zhang, Yufan Lv, Xinyu Luo, Jieya Qiu, Jianhong Zuo
Article Number: 217
Published online on: 02 April 2026

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Case Report Open Access

Comprehensive treatment for intracranial invasive sinonasal intestinal‑type adenocarcinoma with a focus on radiotherapy dosage and immunological combination therapy: A case report

Lianlian Yang, Qian Zhao, Fang Yi, Wenyan Guo, Qiongwen Zhang, Song Zhou, Dong Li, Zhihui Li
Article Number: 216
Published online on: 02 April 2026

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Review Open Access

Biological basis and clinical translation prospects of circulating cell‑free DNA in precision management of breast cancer (Review)

Li-Zhuang Fan, Ai-Lan Xu, Ya-Ru Xu, Luo Yang, Fang Yuan, Xin Nie
Article Number: 215
Published online on: 02 April 2026

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Review Open Access

Cutting‑edge advances in endocrine therapy for breast cancer (Review)

Yumei Dong, Lihua Shao, Qiong Li, Yuexiao Qi, Tingting Liu, Shihong Wei, Haiyan Qi
Article Number: 214
Published online on: 02 April 2026

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Case Report Open Access

Rapidly progressive squamous lung cancer with peripheral blood eosinophilia in a 25-year-old woman: A case report

Mingrui Zhang, Huanfang Fan, Chunxia Sun, Dehui Li, Jiangya Gan, Yun He, Jiaqi Chen
Article Number: 213
Published online on: 02 April 2026

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Article Open Access

Dynamic curve type serves as an effective tool for the diagnosis of benign or malignant non‑mass enhancements on breast MRI

Tara Farooq Kareem, Areege Mustafa Kamal, Munawar Al Nakash
Article Number: 212
Published online on: 02 April 2026

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Article Open Access

Clinical predictors of leptomeningeal metastasis from lung adenocarcinoma based on retrospective analysis

Yunyun Lu, Yi Lu, Yueyue Zhang, Hongyuan Du, Xuan Cao, Dexi Jin, Guofu Chen, Xiaohui Yang
Article Number: 211
Published online on: 01 April 2026

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Expression of Concern Open Access

[Expression of Concern] Delphinidin induces cell cycle arrest and apoptosis in HER‑2 positive breast cancer cell lines by regulating the NF‑κB and MAPK signaling pathways

Ailin Wu, Yanfeng Zhu, Bin Han, Jiayuan Peng, Xiaomin Deng, Wei Chen, Jingchang Du, Yu Ou, Xiaoli Peng, Xiaoping Yu
Article Number: 210
Published online on: 01 April 2026

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Case Report Open Access

Primary thoracic synovial sarcoma in a 45‑year‑old male: A case report and literature review

Baolei Liang, Jichun Zhang, Mingqiang Shen, Cuilian Li, Mingxiao Hou, Yunen Liu, Qingyong Cai
Article Number: 209
Published online on: 31 March 2026

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Expression of Concern Open Access

[Expression of Concern] Pseudomonas aeruginosa‑mannose‑sensitive hema-gglutinin inhibits proliferation and induces apoptosis in a caspase‑dependent manner in human bladder cancer cell lines

Yi-Ping Zhu, Xiao-Jie Bian, Ding-Wei Ye, Xu-Dong Yao, Shi-Lin Zhang, Bo Dai, Yi-Jun Shen
Article Number: 208
Published online on: 31 March 2026

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July-2026 Volume 32 Issue 1

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Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Expression of Concern Open Access

[Expression of Concern] FHOD1 is upregulated in gastric cancer and promotes the proliferation and invasion of gastric cancer cells

Chengfei Jiang, Binbin Yuan, Bo Hang, Jian-Hua Mao, Xiaoping Zou, Pin Wang
Article Number: 277
Published online on: 29 April 2026

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Review Open Access

Watch‑and‑wait in rectal cancer: A critical appraisal of promise, perils and unresolved contours of organ preservation (Review)

Xinqiang Zhu, Beibei Ge, Linchun Wen, Siwei Shan
Article Number: 276
Published online on: 28 April 2026

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Review Open Access

Multi‑omics profiling of pancreatic neuroendocrine tumors: Interplay of genomic instability and the tumor microenvironment (Review)

Yin Wan, Yingnan Zhang, Philip A. Philip, Herbert Chen, Bassel El‑Rayes, Asfar S. Azmi, Yang Shi
Article Number: 275
Published online on: 28 April 2026

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Article Open Access

SOX2‑positive upper tract urothelial carcinoma: Clinicopathological characteristics and therapeutic implications

Hitomi Yasukawa, Yoshinori Ikehata, Naotaka Nishiyama, Hiroshi Kitamura
Article Number: 274
Published online on: 28 April 2026

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Article Open Access

Diagnostic and therapeutic challenges of locally advanced colon cancer complicated with acute lymphoblastic leukemia: A case report

Yuping Zeng, Song Mu, Guosheng Li, Zhengzi Liang, Qinghua Ji, Yunhuan Zhen, Wenling Wang, Weiwei Chen
Article Number: 273
Published online on: 28 April 2026

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Article Open Access

LINC00184 promotes esophageal squamous cell carcinoma progression via DNMT1‑mediated methylation of the NDRG2 promoter and PI3K/AKT pathway activation

Junjun Guo, Shenbo Fu, Jia Liu, Lina Li, Jin Zhao, Fenggang Wang, Wenan Wu, Xu Chen, Enxiao Li
Article Number: 272
Published online on: 28 April 2026

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Article Open Access

A clear cell sarcoma tumor of the finger with an unusual presentation misdiagnosed as a glomus tumor in an adolescent patient: A case report

Abdulrahman Alaseem, Hatim Khoja, Khalid Murrad, Sarah Alkhalife, Nouf Altwaijri, Abdullah Almawi, Abdulaziz Bin Dakhil, Abdulaziz Alhammad, Banan Alqady, Eman Najjar
Article Number: 271
Published online on: 28 April 2026

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Case Report Open Access

Primary thyroid lymphoma with Hashimoto's thyroiditis: A case report and literature review

Fangshu Liu, Xueya Xin, Kai Tan, Xinv Chen, Chanjuan Shen, Qiuhong Yang
Article Number: 270
Published online on: 28 April 2026

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Expression of Concern Open Access

[Expression of Concern] In vitro and in vivo inhibition of tumor cell viability by combined dihydroartemisinin and doxorubicin treatment, and the underlying mechanism

Xiang Tai, Xiao-Bei Cai, Zhang Zhang, Rui Wei
Article Number: 269
Published online on: 28 April 2026

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