Journal Articles
Review
Preservation of fertility in patients with cancer (Review)
Sofía Del‑Pozo‑Lérida, Cristina Salvador, Fina Martínez‑Soler, Avelina Tortosa, Manuel Perucho, Pepita Giménez‑Bonafé
Pages: 2607-2614 Published online on: 14 March 2019
Review
Survivin overexpression in head and neck squamous cell carcinomas as a new therapeutic target (Review)
M. A. Frassanito, I. Saltarella, A. Vinella, L. Lo Muzio, G. Pannone, R. Fumarulo, A. Vacca, M. A. Mariggiò
Pages: 2615-2624 Published online on: 21 March 2019
Review
Role of natural killer cells for immunotherapy in chronic myeloid leukemia (Review)
Hye‑Rim Lee, Kwang‑Hyun Baek
Pages: 2625-2635 Published online on: 13 March 2019
Article
The PI3K inhibitor buparlisib suppresses osteoclast formation and tumour cell growth in bone metastasis of lung cancer, as evidenced by multimodality molecular imaging
Shengfei Wang, Xiaomin Niu, Xiao Bao, Qin Wang, Jianping Zhang, Shun Lu, Yongjun Wang, Ling Xu, Mingwei Wang, Jie Zhang
Pages: 2636-2646 Published online on: 20 March 2019
Article
MicroRNA-216a suppresses the proliferation and migration of human breast cancer cells via the Wnt/β-catenin signaling pathway
Qing Xie, Shuai Wang, Yue Zhao, Zhenchao Zhang, Chuan Qin, Xianjun Yang
Pages: 2647-2656 Published online on: 07 March 2019
Article
PARG regulates the proliferation and differentiation of DCs and T cells via PARP/NF‑κB in tumour metastases of colon carcinoma
Jie‑Qiong Wang, Yi Tang, Qing‑Shu Li, Ming Xiao, Ming Li, Yong‑Tao Sheng, Yi Yang, Ya‑Lan Wang
Pages: 2657-2666 Published online on: 07 March 2019
Article
Targeting P16INK4A in uterine serous carcinoma through inhibition of histone demethylation
Zhen Xiao, Yingying He, Chongya Liu, Lin Xiang, Jingyan Yi, Min Wang, Tingting Shen, Lanlin Shen, Yijue Xue, Hong Shi, Pixu Liu
Pages: 2667-2678 Published online on: 14 March 2019
Article
CD1d highly expressed on DCs reduces lung tumor burden by enhancing antitumor immunity
Yifan Li, Chujun Zhao, Jiajing Liu, Zhou Lu, Mingfang Lu, Jie Gu, Ronghua Liu
Pages: 2679-2688 Published online on: 28 February 2019
Article
Combination of phospholipase Cε knockdown with GANT61 sensitizes castration‑resistant prostate cancer cells to enzalutamide by suppressing the androgen receptor signaling pathway Corrigendum in /10.3892/or.2022.8426
Wei Sun, Luo Li, Zhongbo Du, Zhen Quan, Mengjuan Yuan, Honglin Cheng, Yingying Gao, Chunli Luo, Xiaohou Wu
Pages: 2689-2702 Published online on: 07 March 2019
Article
Hyperbaric oxygen increases glioma cell sensitivity to antitumor treatment with a novel isothiourea derivative in vitro
Katarzyna Zembrzuska, Robert P. Ostrowski, Ewa Matyja
Pages: 2703-2716 Published online on: 14 March 2019
Article
Rab1A promotes proliferation and migration abilities via regulation of the HER2/AKT-independent mTOR/S6K1 pathway in colorectal cancer
Zhengwu Cheng, Xinyu Shao, Menglin Xu, Junfeng Wang, Xiaoyi Kuai, Liping Zhang, Jian Wu, Chunli Zhou, Jiading Mao
Pages: 2717-2728 Published online on: 15 March 2019
Article
miR-363 acts as a tumor suppressor in osteosarcoma cells by inhibiting PDZD2
Fan He, Long Fang, Qingshui Yin
Pages: 2729-2738 Published online on: 19 March 2019
Article
Overexpression of IC53d promotes the proliferation of gastric cancer cells by activating the AKT/GSK3β/cyclin D1 signaling pathway
Jian‑Xian Lin, Xin‑Sheng Xie, Xiong‑Feng Weng, Sheng‑Liang Qiu, Jian‑Wei Xie, Jia‑Bin Wang, Jun Lu, Qi‑Yue Chen, Long‑Long Cao, Mi Lin, Ru‑Hong Tu, Ping Li, Chang‑Ming Huang, Chao‑Hui Zheng
Pages: 2739-2752 Published online on: 05 March 2019
Article
LATS2 inhibits cell proliferation and metastasis through the Hippo signaling pathway in glioma
Chengyong Guo, Chaohui Liang, Jipeng Yang, Hongchao Hu, Bo Fan, Xin Liu
Pages: 2753-2761 Published online on: 14 March 2019
Article
Genome‑wide DNA methylation profile of thymomas and potential epigenetic regulation of thymoma subtypes
Yalan Bi, Yunxiao Meng, Yuchen Niu, Shanqing Li, Hongsheng Liu, Jia He, Ye Zhang, Naixin Liang, Lei Liu, Xinxin Mao, Jie Yan, Bo Long, Zhiyong Liang, Zhihong Wu
Pages: 2762-2774 Published online on: 28 February 2019
Article
Analysis of microRNA expression profiles reveals a 5‑microRNA prognostic signature for predicting overall survival time in patients with gastric adenocarcinoma
Ruihong Zhao, Lei Zhao, Xu Xu, Hong Xu
Pages: 2775-2789 Published online on: 07 March 2019
Article
Interaction with tumor‑associated macrophages promotes PRL‑3‑induced invasion of colorectal cancer cells via MAPK pathway‑induced EMT and NF‑κB signaling‑induced angiogenesis
Tao Zhang, Lu Liu, Wei Lai, Yujie Zeng, Heyang Xu, Qiusheng Lan, Pengwei Su, Zhonghua Chu
Pages: 2790-2802 Published online on: 07 March 2019
Article
Non‑covalent proteasome inhibitor PI‑1840 induces apoptosis and autophagy in osteosarcoma cells
Yuxi Chen, Hongjun Chen, Hui Xie, Shaohui Yuan, Chuanbo Gao, Lei Yu, Zhenggang Bi
Pages: 2803-2817 Published online on: 01 March 2019
Article
Recombinant adenoviruses expressing apoptin suppress the growth of MCF‑7 breast cancer cells and affect cell autophagy
Shuang Chen, Yi‑Quan Li, Xun‑Zhe Yin, Shan‑Zhi Li, Yi‑Long Zhu, Yuan‑Yuan Fan, Wen‑Jie Li, Ying‑Li Cui, Jin Zhao, Xiao Li, Qing‑Gao Zhang, Ning‑Yi Jin
Pages: 2818-2832 Published online on: 18 March 2019
Article
PD‑L1 promotes head and neck squamous cell carcinoma cell growth through mTOR signaling
Anyuan Zheng, Fen Li, Fuhai Chen, Jingjing Zuo, Lei Wang, Yongping Wang, Shiming Chen, Bokui Xiao, Zezhang Tao
Pages: 2833-2843 Published online on: 07 March 2019
Article
PLCε promotes urinary bladder cancer cells proliferation through STAT3/LDHA pathway‑mediated glycolysis
Honglin Cheng, Yanni Hao, Yingying Gao, Yunfeng He, Chunli Luo, Wei Sun, Mengjuan Yuan, Xiaohou Wu
Pages: 2844-2854 Published online on: 13 March 2019
Article
Diagnostic and prognostic value of mRNA expression of phospholipase C β family genes in hepatitis B virus‑associated hepatocellular carcinoma
Xiangkun Wang, Ketuan Huang, Xianmin Zeng, Zhengqian Liu, Xiwen Liao, Chengkun Yang, Tingdong Yu, Chuangye Han, Guangzhi Zhu, Wei Qin, Tao Peng
Pages: 2855-2875 Published online on: 14 March 2019
Article
Genome-scale integrated analysis to identify prospective molecular mechanisms and therapeutic targets in isocitrate dehydrogenase 2 R140Q-mutated acute myeloid leukemia
Rui Huang, Xiwen Liao, Jing Li, Jiemin Wei, Xiayun Su, Xiaoxuan Lai, Beicai Liu, Fangxiao Zhu, Yumei Huang, Qiaochuan Li
Pages: 2876-2888 Published online on: 18 March 2019
Article
Y‑box‑binding protein 1 inhibits apoptosis and upregulates EGFR in colon cancer
Sachiko Nagasu, Tomoya Sudo, Tetsushi Kinugasa, Takatou Yomoda, Kenji Fujiyoshi, Takahiro Shigaki, Yoshito Akagi
Pages: 2889-2896 Published online on: 28 February 2019
Article
miR‑146a regulates the function of Th17 cell differentiation to modulate cervical cancer cell growth and apoptosis through NF‑κB signaling by targeting TRAF6
Tian Li, Mengxiong Li, Chengfang Xu, Xiaoyu Xu, Jie Ding, Li Cheng, Rongying Ou
Pages: 2897-2908 Published online on: 07 March 2019
Article
Higher tumor mass and lower adipose mass are associated with colon‑26 adenocarcinoma‑induced cachexia in male, female and ovariectomized mice
Taylor Banh, Deena Snoke, Rachel M. Cole, Austin Angelotti, Patrick M. Schnell, Martha A. Belury
Pages: 2909-2918 Published online on: 20 March 2019
Article
Wound fluid enhances cancer cell proliferation via activation of STAT3 signal pathway in vitro
Agmal Scherzad, Thomas Gehrke, Till Meyer, Pascal Ickrath, Maximilian Bregenzer, Rafael Eiter, Rudolf Hagen, Norbert Kleinsasser, Stephan Hackenberg
Pages: 2919-2926 Published online on: 07 March 2019
Article
5‑Azacytidine treatment results in nuclear exclusion of DNA methyltransferase‑1, as well as reduced proliferation and invasion in human cytomegalovirus‑infected glioblastoma cells
Atosa Estekizadeh, Natalia Landázuri, Mattia Russel Pantalone, Belghis Davoudi, Li‑Fu Hu, Imran Nawaz, Giuseppe Stragliotto, Tomas J. Ekström, Afsar Rahbar
Pages: 2927-2936 Published online on: 18 March 2019
Article
Timosaponin A‑III induces autophagy of T‑cell acute lymphoblastic leukemia Jurkat cells via inhibition of the PI3K/Akt/mTOR pathway
Hong Wang, Rui Dong, Wen‑Wen Fan, Xing‑Chang Zheng, Ai‑Min Li, Wen‑Di Wang
Pages: 2937-2944 Published online on: 15 March 2019
Article
CD147‑mediated reprogrammed glycolytic metabolism potentially induces immune escape in the tumor microenvironment (Review)
Xiaofeng Li, Wengui Xu
Pages: 2945-2956 Published online on: 04 March 2019
Article
LncRNA‑AB209371 promotes the epithelial‑mesenchymal transition of hepatocellular carcinoma cells
Chaocheng Xiao, Xinqiang Wan, Haiyang Yu, Xiaotong Chen, Xiangxiang Shan, Yufeng Miao, Rengen Fan, Wenzhang Cha
Pages: 2957-2966 Published online on: 07 March 2019
Article
Downregulation of estrogen receptor β inhibits lung adenocarcinoma cell growth
Wenjuan Chen, Bo Xin, Hailin Pang, Le Han, Weiwei Shen, Zheng Zhao, Lian Duan, Peipei Cao, Lili Liu, Helong Zhang
Pages: 2967-2974 Published online on: 05 March 2019
Article
Astragaloside IV inhibits the invasion and metastasis of SiHa cervical cancer cells via the TGF‑β1‑mediated PI3K and MAPK pathways
Lei Zhang, Jie Zhou, Xiaokang Qin, Huaming Huang, Chao Nie
Pages: 2975-2986 Published online on: 13 March 2019
Article
Antitumor effects of hsa‑miR661‑3p on non‑small cell lung cancer in vivo and in vitro
Jingjing Lu, Xia Gu, Fanglei Liu, Zhuanghua Rui, Ming Liu, Liming Zhao
Pages: 2987-2996 Published online on: 21 March 2019
Article
Metabolic dependence of cyclosporine A on cell proliferation of human non‑small cell lung cancer A549 cells and its implication in post‑transplant malignancy
Xinghua Qin, Ziwei Chen
Pages: 2997-3004 Published online on: 18 March 2019
Article
LASS2 inhibits proliferation and induces apoptosis in HepG2 cells by affecting mitochondrial dynamics, the cell cycle and the nuclear factor‑κB pathways
Yan Yang, Xiaoli Yang, Lin Li, Gangyi Yang, Xuhong Ouyang, Jialin Xiang, Tao Zhang, Xun Min
Pages: 3005-3014 Published online on: 13 March 2019
Article
Downregulation of cytokeratin 18 enhances BCRP-mediated multidrug resistance through induction of epithelial-mesenchymal transition and predicts poor prognosis in breast cancer
Ruizan Shi, Chang Wang, Naijie Fu, Linhong Liu, Diying Zhu, Zehui Wei, Huifeng Zhang, Jianfeng Xing, Yan Wang
Pages: 3015-3026 Published online on: 15 March 2019
Article
Construction of ceRNA networks reveals differences between distal and proximal colon cancers
Wenwei Qian, Yifei Feng, Jie Li, Wen Peng, Qiou Gu, Zhiyuan Zhang, Dongjian Ji, Qingyuan Wang, Dongsheng Zhang, Yueming Sun
Pages: 3027-3040 Published online on: 21 March 2019
Article
Predictive value of the ratio of 8‑hydroxydeoxyguanosine levels between cancerous and normal tissues in patients with stage II/III colorectal cancer
Hiroshi Kitagawa, Yoshihiko Kitajima, Keita Kai, Sho Komukai, Tomokazu Tanaka, Yasuo Koga, Tatsuya Manabe, Hirokazu Noshirο
Pages: 3041-3050 Published online on: 22 March 2019
Article
Hepatitis C virus nonstructural 5A protein inhibits the starvation‑induced apoptosis of hepatoblastoma cells by increasing Beclin 1 expression
Min Quan, Shunai Liu, Li Zhou, Shenghu Feng, Yu Zhang, Jun Cheng
Pages: 3051-3059 Published online on: 13 March 2019
Article
Tropomodulin 3 promotes liver cancer progression by activating the MAPK/ERK signaling pathway
Canguang Jin, Zhikang Chen, Wei Shi, Qi Lian
Pages: 3060-3068 Published online on: 07 March 2019
Article
Songorine suppresses cell growth and metastasis in epithelial ovarian cancer via the Bcl‑2/Bax and GSK3β/β‑catenin signaling pathways
Hongxia Zhang, Ruifeng Dong, Ping Zhang, Yankui Wang
Pages: 3069-3079 Published online on: 15 March 2019
Article
Proteins of the Wnt signaling pathway as targets for the regulation of CD133+ cancer stem cells in glioblastoma
Valery Shevchenko, Nataliya Arnotskaya, Maria Korneyko, Sergry Zaytsev, Yuriy Khotimchenko, Hary Sharma, Igor Bryukhovetskiy
Pages: 3080-3088 Published online on: 05 March 2019
Article
Transcriptome‑wide piRNA profiling in human gastric cancer
Xiandong Lin, Yan Xia, Dan Hu, Qiao Mao, Zongyang Yu, Hejun Zhang, Chao Li, Gang Chen, Fen Liu, Weifeng Zhu, Yi Shi, Huihao Zhang, Jianming Zheng, Tao Sun, Jianying Xu, Herta H. Chao, Xiongwei Zheng, Xingguang Luο
Pages: 3089-3099 Published online on: 18 March 2019
Article
Microwave hyperthermia enhances the sensitivity of lung cancer cells to gemcitabine through reactive oxygen species‑induced autophagic death
Yang Yang, Chun‑Li Yang, Zhen‑Jiang Zhao, Xiao‑Xiao Zuo, Tian‑Song Liang, Ya Yang, Sheng‑Lin Ma, Dao‑Ke Yang
Pages: 3100-3110 Published online on: 22 March 2019
Article
Transcribed ultraconserved region Uc.63+ promotes resistance to cisplatin through regulation of androgen receptor signaling in bladder cancer
Yohei Sekino, Naoya Sakamoto, Akira Ishikawa, Ririno Honma, Yoshinori Shigematsu, Tetsutaro Hayashi, Kazuhiro Sentani, Naohide Oue, Jun Teishima, Akio Matsubara, Wataru Yasui
Pages: 3111-3118 Published online on: 28 February 2019
Article
Induction of HSP27 and HSP70 by constitutive overexpression of Redd1 confers resistance of lung cancer cells to ionizing radiation
Hyeon‑Ok Jin, Sung‑Eun Hong, Ji‑Young Kim, Mi‑Ri Kim, Yoon Hwan Chang, Young Jun Hong, Jin Kyung Lee, In‑Chul Park
Pages: 3119-3126 Published online on: 28 February 2019
Article
Selected nitrostyrene compounds demonstrate potent activity in chronic lymphocytic leukaemia cells, including those with poor prognostic markers
S. A. Bright, A. J. Byrne, E. Vandenberghe, P. V. Browne, A. M. Mcelligott, M. J. Meegan, D. C. Williams
Pages: 3127-3136 Published online on: 15 March 2019
Article
microRNA‑485 inhibits the malignant behaviors of retinoblastoma by directly targeting Wnt3a Retraction in /10.3892/or.2022.8347
Xueman Lyu, Ling Wang, Jia Lu, Hong Zhang, Lina Wang
Pages: 3137-3147 Published online on: 13 March 2019
Correction
[Corrigendum] miR-9 regulates the multidrug resistance of chronic myelogenous leukemia by targeting ABCB1
Yan Li, Lifen Zhao, Nana Li, Yuan Miao, Huimin Zhou, Li Jia
Pages: 3148-3148 Published online on: 13 March 2019
Correction