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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
May-2019 Volume 41 Issue 5

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

Preservation of fertility in patients with cancer (Review)

Sofía Del‑Pozo‑Lérida, Cristina Salvador, Fina Martínez‑Soler, Avelina Tortosa, Manuel Perucho, Pepita Giménez‑Bonafé
Pages: 2607-2614
Published online on: 14 March 2019

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Review

Survivin overexpression in head and neck squamous cell carcinomas as a new therapeutic target (Review)

M. A. Frassanito, I. Saltarella, A. Vinella, L. Lo Muzio, G. Pannone, R. Fumarulo, A. Vacca, M. A. Mariggiò
Pages: 2615-2624
Published online on: 21 March 2019

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Review

Role of natural killer cells for immunotherapy in chronic myeloid leukemia (Review)

Hye‑Rim Lee, Kwang‑Hyun Baek
Pages: 2625-2635
Published online on: 13 March 2019

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Article Open Access

The PI3K inhibitor buparlisib suppresses osteoclast formation and tumour cell growth in bone metastasis of lung cancer, as evidenced by multimodality molecular imaging

Shengfei Wang, Xiaomin Niu, Xiao Bao, Qin Wang, Jianping Zhang, Shun Lu, Yongjun Wang, Ling Xu, Mingwei Wang, Jie Zhang
Pages: 2636-2646
Published online on: 20 March 2019

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Article Open Access

MicroRNA-216a suppresses the proliferation and migration of human breast cancer cells via the Wnt/β-catenin signaling pathway

Qing Xie, Shuai Wang, Yue Zhao, Zhenchao Zhang, Chuan Qin, Xianjun Yang
Pages: 2647-2656
Published online on: 07 March 2019

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Article Open Access

PARG regulates the proliferation and differentiation of DCs and T cells via PARP/NF‑κB in tumour metastases of colon carcinoma

Jie‑Qiong Wang, Yi Tang, Qing‑Shu Li, Ming Xiao, Ming Li, Yong‑Tao Sheng, Yi Yang, Ya‑Lan Wang
Pages: 2657-2666
Published online on: 07 March 2019

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Article Open Access

Targeting P16INK4A in uterine serous carcinoma through inhibition of histone demethylation

Zhen Xiao, Yingying He, Chongya Liu, Lin Xiang, Jingyan Yi, Min Wang, Tingting Shen, Lanlin Shen, Yijue Xue, Hong Shi, Pixu Liu
Pages: 2667-2678
Published online on: 14 March 2019

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Article Open Access

CD1d highly expressed on DCs reduces lung tumor burden by enhancing antitumor immunity

Yifan Li, Chujun Zhao, Jiajing Liu, Zhou Lu, Mingfang Lu, Jie Gu, Ronghua Liu
Pages: 2679-2688
Published online on: 28 February 2019

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Article Open Access

Combination of phospholipase Cε knockdown with GANT61 sensitizes castration‑resistant prostate cancer cells to enzalutamide by suppressing the androgen receptor signaling pathway Corrigendum in /10.3892/or.2022.8426

Wei Sun, Luo Li, Zhongbo Du, Zhen Quan, Mengjuan Yuan, Honglin Cheng, Yingying Gao, Chunli Luo, Xiaohou Wu
Pages: 2689-2702
Published online on: 07 March 2019

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Article Open Access

Hyperbaric oxygen increases glioma cell sensitivity to antitumor treatment with a novel isothiourea derivative in vitro

Katarzyna Zembrzuska, Robert P. Ostrowski, Ewa Matyja
Pages: 2703-2716
Published online on: 14 March 2019

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Article Open Access

Rab1A promotes proliferation and migration abilities via regulation of the HER2/AKT-independent mTOR/S6K1 pathway in colorectal cancer

Zhengwu Cheng, Xinyu Shao, Menglin Xu, Junfeng Wang, Xiaoyi Kuai, Liping Zhang, Jian Wu, Chunli Zhou, Jiading Mao
Pages: 2717-2728
Published online on: 15 March 2019

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Article Open Access

miR-363 acts as a tumor suppressor in osteosarcoma cells by inhibiting PDZD2

Fan He, Long Fang, Qingshui Yin
Pages: 2729-2738
Published online on: 19 March 2019

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Article Open Access

Overexpression of IC53d promotes the proliferation of gastric cancer cells by activating the AKT/GSK3β/cyclin D1 signaling pathway

Jian‑Xian Lin, Xin‑Sheng Xie, Xiong‑Feng Weng, Sheng‑Liang Qiu, Jian‑Wei Xie, Jia‑Bin Wang, Jun Lu, Qi‑Yue Chen, Long‑Long Cao, Mi Lin, Ru‑Hong Tu, Ping Li, Chang‑Ming Huang, Chao‑Hui Zheng
Pages: 2739-2752
Published online on: 05 March 2019

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Article Open Access

LATS2 inhibits cell proliferation and metastasis through the Hippo signaling pathway in glioma

Chengyong Guo, Chaohui Liang, Jipeng Yang, Hongchao Hu, Bo Fan, Xin Liu
Pages: 2753-2761
Published online on: 14 March 2019

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Article Open Access

Genome‑wide DNA methylation profile of thymomas and potential epigenetic regulation of thymoma subtypes

Yalan Bi, Yunxiao Meng, Yuchen Niu, Shanqing Li, Hongsheng Liu, Jia He, Ye Zhang, Naixin Liang, Lei Liu, Xinxin Mao, Jie Yan, Bo Long, Zhiyong Liang, Zhihong Wu
Pages: 2762-2774
Published online on: 28 February 2019

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Article Open Access

Analysis of microRNA expression profiles reveals a 5‑microRNA prognostic signature for predicting overall survival time in patients with gastric adenocarcinoma

Ruihong Zhao, Lei Zhao, Xu Xu, Hong Xu
Pages: 2775-2789
Published online on: 07 March 2019

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Article Open Access

Interaction with tumor‑associated macrophages promotes PRL‑3‑induced invasion of colorectal cancer cells via MAPK pathway‑induced EMT and NF‑κB signaling‑induced angiogenesis

Tao Zhang, Lu Liu, Wei Lai, Yujie Zeng, Heyang Xu, Qiusheng Lan, Pengwei Su, Zhonghua Chu
Pages: 2790-2802
Published online on: 07 March 2019

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Article Open Access

Non‑covalent proteasome inhibitor PI‑1840 induces apoptosis and autophagy in osteosarcoma cells

Yuxi Chen, Hongjun Chen, Hui Xie, Shaohui Yuan, Chuanbo Gao, Lei Yu, Zhenggang Bi
Pages: 2803-2817
Published online on: 01 March 2019

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Article Open Access

Recombinant adenoviruses expressing apoptin suppress the growth of MCF‑7 breast cancer cells and affect cell autophagy

Shuang Chen, Yi‑Quan Li, Xun‑Zhe Yin, Shan‑Zhi Li, Yi‑Long Zhu, Yuan‑Yuan Fan, Wen‑Jie Li, Ying‑Li Cui, Jin Zhao, Xiao Li, Qing‑Gao Zhang, Ning‑Yi Jin
Pages: 2818-2832
Published online on: 18 March 2019

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Article Open Access

PD‑L1 promotes head and neck squamous cell carcinoma cell growth through mTOR signaling

Anyuan Zheng, Fen Li, Fuhai Chen, Jingjing Zuo, Lei Wang, Yongping Wang, Shiming Chen, Bokui Xiao, Zezhang Tao
Pages: 2833-2843
Published online on: 07 March 2019

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Article Open Access

PLCε promotes urinary bladder cancer cells proliferation through STAT3/LDHA pathway‑mediated glycolysis

Honglin Cheng, Yanni Hao, Yingying Gao, Yunfeng He, Chunli Luo, Wei Sun, Mengjuan Yuan, Xiaohou Wu
Pages: 2844-2854
Published online on: 13 March 2019

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Article Open Access

Diagnostic and prognostic value of mRNA expression of phospholipase C β family genes in hepatitis B virus‑associated hepatocellular carcinoma

Xiangkun Wang, Ketuan Huang, Xianmin Zeng, Zhengqian Liu, Xiwen Liao, Chengkun Yang, Tingdong Yu, Chuangye Han, Guangzhi Zhu, Wei Qin, Tao Peng
Pages: 2855-2875
Published online on: 14 March 2019

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Article Open Access

Genome-scale integrated analysis to identify prospective molecular mechanisms and therapeutic targets in isocitrate dehydrogenase 2 R140Q-mutated acute myeloid leukemia

Rui Huang, Xiwen Liao, Jing Li, Jiemin Wei, Xiayun Su, Xiaoxuan Lai, Beicai Liu, Fangxiao Zhu, Yumei Huang, Qiaochuan Li
Pages: 2876-2888
Published online on: 18 March 2019

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Article

Y‑box‑binding protein 1 inhibits apoptosis and upregulates EGFR in colon cancer

Sachiko Nagasu, Tomoya Sudo, Tetsushi Kinugasa, Takatou Yomoda, Kenji Fujiyoshi, Takahiro Shigaki, Yoshito Akagi
Pages: 2889-2896
Published online on: 28 February 2019

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Article

miR‑146a regulates the function of Th17 cell differentiation to modulate cervical cancer cell growth and apoptosis through NF‑κB signaling by targeting TRAF6

Tian Li, Mengxiong Li, Chengfang Xu, Xiaoyu Xu, Jie Ding, Li Cheng, Rongying Ou
Pages: 2897-2908
Published online on: 07 March 2019

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Article

Higher tumor mass and lower adipose mass are associated with colon‑26 adenocarcinoma‑induced cachexia in male, female and ovariectomized mice

Taylor Banh, Deena Snoke, Rachel M. Cole, Austin Angelotti, Patrick M. Schnell, Martha A. Belury
Pages: 2909-2918
Published online on: 20 March 2019

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Article

Wound fluid enhances cancer cell proliferation via activation of STAT3 signal pathway in vitro

Agmal Scherzad, Thomas Gehrke, Till Meyer, Pascal Ickrath, Maximilian Bregenzer, Rafael Eiter, Rudolf Hagen, Norbert Kleinsasser, Stephan Hackenberg
Pages: 2919-2926
Published online on: 07 March 2019

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Article

5‑Azacytidine treatment results in nuclear exclusion of DNA methyltransferase‑1, as well as reduced proliferation and invasion in human cytomegalovirus‑infected glioblastoma cells

Atosa Estekizadeh, Natalia Landázuri, Mattia Russel Pantalone, Belghis Davoudi, Li‑Fu Hu, Imran Nawaz, Giuseppe Stragliotto, Tomas J. Ekström, Afsar Rahbar
Pages: 2927-2936
Published online on: 18 March 2019

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Article

Timosaponin A‑III induces autophagy of T‑cell acute lymphoblastic leukemia Jurkat cells via inhibition of the PI3K/Akt/mTOR pathway

Hong Wang, Rui Dong, Wen‑Wen Fan, Xing‑Chang Zheng, Ai‑Min Li, Wen‑Di Wang
Pages: 2937-2944
Published online on: 15 March 2019

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Article

CD147‑mediated reprogrammed glycolytic metabolism potentially induces immune escape in the tumor microenvironment (Review)

Xiaofeng Li, Wengui Xu
Pages: 2945-2956
Published online on: 04 March 2019

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Article

LncRNA‑AB209371 promotes the epithelial‑mesenchymal transition of hepatocellular carcinoma cells

Chaocheng Xiao, Xinqiang Wan, Haiyang Yu, Xiaotong Chen, Xiangxiang Shan, Yufeng Miao, Rengen Fan, Wenzhang Cha
Pages: 2957-2966
Published online on: 07 March 2019

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Article

Downregulation of estrogen receptor β inhibits lung adenocarcinoma cell growth

Wenjuan Chen, Bo Xin, Hailin Pang, Le Han, Weiwei Shen, Zheng Zhao, Lian Duan, Peipei Cao, Lili Liu, Helong Zhang
Pages: 2967-2974
Published online on: 05 March 2019

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Article

Astragaloside IV inhibits the invasion and metastasis of SiHa cervical cancer cells via the TGF‑β1‑mediated PI3K and MAPK pathways

Lei Zhang, Jie Zhou, Xiaokang Qin, Huaming Huang, Chao Nie
Pages: 2975-2986
Published online on: 13 March 2019

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Article

Antitumor effects of hsa‑miR661‑3p on non‑small cell lung cancer in vivo and in vitro

Jingjing Lu, Xia Gu, Fanglei Liu, Zhuanghua Rui, Ming Liu, Liming Zhao
Pages: 2987-2996
Published online on: 21 March 2019

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Article

Metabolic dependence of cyclosporine A on cell proliferation of human non‑small cell lung cancer A549 cells and its implication in post‑transplant malignancy

Xinghua Qin, Ziwei Chen
Pages: 2997-3004
Published online on: 18 March 2019

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Article

LASS2 inhibits proliferation and induces apoptosis in HepG2 cells by affecting mitochondrial dynamics, the cell cycle and the nuclear factor‑κB pathways

Yan Yang, Xiaoli Yang, Lin Li, Gangyi Yang, Xuhong Ouyang, Jialin Xiang, Tao Zhang, Xun Min
Pages: 3005-3014
Published online on: 13 March 2019

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Article

Downregulation of cytokeratin 18 enhances BCRP-mediated multidrug resistance through induction of epithelial-mesenchymal transition and predicts poor prognosis in breast cancer

Ruizan Shi, Chang Wang, Naijie Fu, Linhong Liu, Diying Zhu, Zehui Wei, Huifeng Zhang, Jianfeng Xing, Yan Wang
Pages: 3015-3026
Published online on: 15 March 2019

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Article

Construction of ceRNA networks reveals differences between distal and proximal colon cancers

Wenwei Qian, Yifei Feng, Jie Li, Wen Peng, Qiou Gu, Zhiyuan Zhang, Dongjian Ji, Qingyuan Wang, Dongsheng Zhang, Yueming Sun
Pages: 3027-3040
Published online on: 21 March 2019

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Article

Predictive value of the ratio of 8‑hydroxydeoxyguanosine levels between cancerous and normal tissues in patients with stage II/III colorectal cancer

Hiroshi Kitagawa, Yoshihiko Kitajima, Keita Kai, Sho Komukai, Tomokazu Tanaka, Yasuo Koga, Tatsuya Manabe, Hirokazu Noshirο
Pages: 3041-3050
Published online on: 22 March 2019

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Article

Hepatitis C virus nonstructural 5A protein inhibits the starvation‑induced apoptosis of hepatoblastoma cells by increasing Beclin 1 expression

Min Quan, Shunai Liu, Li Zhou, Shenghu Feng, Yu Zhang, Jun Cheng
Pages: 3051-3059
Published online on: 13 March 2019

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Article

Tropomodulin 3 promotes liver cancer progression by activating the MAPK/ERK signaling pathway

Canguang Jin, Zhikang Chen, Wei Shi, Qi Lian
Pages: 3060-3068
Published online on: 07 March 2019

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Article

Songorine suppresses cell growth and metastasis in epithelial ovarian cancer via the Bcl‑2/Bax and GSK3β/β‑catenin signaling pathways

Hongxia Zhang, Ruifeng Dong, Ping Zhang, Yankui Wang
Pages: 3069-3079
Published online on: 15 March 2019

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Article

Proteins of the Wnt signaling pathway as targets for the regulation of CD133+ cancer stem cells in glioblastoma

Valery Shevchenko, Nataliya Arnotskaya, Maria Korneyko, Sergry Zaytsev, Yuriy Khotimchenko, Hary Sharma, Igor Bryukhovetskiy
Pages: 3080-3088
Published online on: 05 March 2019

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Article

Transcriptome‑wide piRNA profiling in human gastric cancer

Xiandong Lin, Yan Xia, Dan Hu, Qiao Mao, Zongyang Yu, Hejun Zhang, Chao Li, Gang Chen, Fen Liu, Weifeng Zhu, Yi Shi, Huihao Zhang, Jianming Zheng, Tao Sun, Jianying Xu, Herta H. Chao, Xiongwei Zheng, Xingguang Luο
Pages: 3089-3099
Published online on: 18 March 2019

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Article

Microwave hyperthermia enhances the sensitivity of lung cancer cells to gemcitabine through reactive oxygen species‑induced autophagic death

Yang Yang, Chun‑Li Yang, Zhen‑Jiang Zhao, Xiao‑Xiao Zuo, Tian‑Song Liang, Ya Yang, Sheng‑Lin Ma, Dao‑Ke Yang
Pages: 3100-3110
Published online on: 22 March 2019

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Article

Transcribed ultraconserved region Uc.63+ promotes resistance to cisplatin through regulation of androgen receptor signaling in bladder cancer

Yohei Sekino, Naoya Sakamoto, Akira Ishikawa, Ririno Honma, Yoshinori Shigematsu, Tetsutaro Hayashi, Kazuhiro Sentani, Naohide Oue, Jun Teishima, Akio Matsubara, Wataru Yasui
Pages: 3111-3118
Published online on: 28 February 2019

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Article

Induction of HSP27 and HSP70 by constitutive overexpression of Redd1 confers resistance of lung cancer cells to ionizing radiation

Hyeon‑Ok Jin, Sung‑Eun Hong, Ji‑Young Kim, Mi‑Ri Kim, Yoon Hwan Chang, Young Jun Hong, Jin Kyung Lee, In‑Chul Park
Pages: 3119-3126
Published online on: 28 February 2019

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Article

Selected nitrostyrene compounds demonstrate potent activity in chronic lymphocytic leukaemia cells, including those with poor prognostic markers

S. A. Bright, A. J. Byrne, E. Vandenberghe, P. V. Browne, A. M. Mcelligott, M. J. Meegan, D. C. Williams
Pages: 3127-3136
Published online on: 15 March 2019

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Article

microRNA‑485 inhibits the malignant behaviors of retinoblastoma by directly targeting Wnt3a Retraction in /10.3892/or.2022.8347

Xueman Lyu, Ling Wang, Jia Lu, Hong Zhang, Lina Wang
Pages: 3137-3147
Published online on: 13 March 2019

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Correction Open Access

[Corrigendum] miR-9 regulates the multidrug resistance of chronic myelogenous leukemia by targeting ABCB1

Yan Li, Lifen Zhao, Nana Li, Yuan Miao, Huimin Zhou, Li Jia
Pages: 3148-3148
Published online on: 13 March 2019

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Correction Open Access

[Corrigendum] NHE1 is upregulated in gastric cancer and regulates gastric cancer cell proliferation, migration and invasion

Rui Xie, Haibo Wang, Hai Jin, Guorong Wen, Biguang Tuo, Jingyu Xu
Pages: 3149-3149
Published online on: 07 March 2019

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Journal Cover
January-2026 Volume 55 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Harnessing ferroptosis for cancer therapy: Mechanisms and therapeutic strategies (Review)

Nabil Mouawad, Nour El Jaafari, Mirvat El Sibai, Ralph J. Abi-Habib
Article Number: 24
Published online on: 24 November 2025

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Expression of Concern Open Access

[Expression of Concern] Promoter methylation of death‑associated protein kinase and its role in irradiation response in cervical cancer

Rebecca Ching-Yu Leung, Stephanie Si Liu, Kelvin Yuen-Kwong Chan, Kar-Fai Tam, Kar-Loen Chan, Ling-Chui Wong, Hextan Yuen-Sheung Ngan
Article Number: 23
Published online on: 24 November 2025

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Article Open Access

Oxaliplatin resistance in pancreatic ductal adenocarcinoma is non‑significantly mediated by diminished drug uptake but is highly linked to a poor apoptotic response to the cytotoxic threat

Hellen Röttgen, Lana Theurer, Teresa Peccerella, Ketaki Sandu, Johanna Weiss, Jürgen Burhenne, John P. Neoptolemos, Beate Köberle, Dirk Theile
Article Number: 22
Published online on: 19 November 2025

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Correction Open Access

[Corrigendum] Src homology phosphotyrosyl phosphatase 2 mediates cisplatin‑related drug resistance by inhibiting apoptosis and activating the Ras/PI3K/Akt1/survivin pathway in lung cancer cells

Chunlan Tang, Hu Luo, Dan Luo, Heping Yang, Xiangdong Zhou
Article Number: 21
Published online on: 19 November 2025

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Article Open Access

S100B drives glioblastoma invasion and migration through TGF‑β2‑mediated epithelial‑mesenchymal transition

Xuemei Liao, Yuan Xu, Honghong Zhou, Qin Yi, Shifang Dong, Bin Tan
Article Number: 20
Published online on: 19 November 2025

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Review Open Access

Role of the SOX family in non‑small cell lung cancer: Molecular mechanisms and therapeutic implications (Review)

Kaiwei Wang, Yaoqi Li, Zhening Guo, Lin Song, Xiaoliang Ding, Linsheng Liu, Tao Hu, Yicong Bian, Chenrong Huang, Liyan Miao
Article Number: 19
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑18a enhances the radiosensitivity of cervical cancer cells by promoting radiation‑induced apoptosis

Sha Liu, Xiaofen Pan, Qin Yang, Lu Wen, Yao Jiang, Yingchao Zhao, Guiling Li
Article Number: 18
Published online on: 17 November 2025

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Review Open Access

Role of histone deacetylases in blood cancer: Exploring peptide‑based inhibitors as therapeutic strategies for leukemia treatment (Review)

Yaneenart Suwanwong, Phornthip Ploensil
Article Number: 17
Published online on: 14 November 2025

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Review Open Access

The multidimensional regulatory network of the PD‑1/PD‑L1 axis in the esophageal squamous cell carcinoma microenvironment: Implications for novel combination therapies and precision immunotherapy (Review)

Haoyue Lai, Lu Qi, Zhixuan Lin, Zhongwen Li
Article Number: 16
Published online on: 13 November 2025

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Review Open Access

From modification to malignancy: Bridging acetylation mechanisms and therapeutic innovations in melanoma (Review)

Jingwen Wu, Xuxia Cai, Zimo Zhu, Xiahong Li, Kaoyuan Zhang, Chenchen Wu, Bo Yu, Cong Huang
Article Number: 15
Published online on: 12 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑92b promotes tumor growth and activation of NF‑κB signaling via regulation of NLK in oral squamous cell carcinoma

Zhiming Liu, Cynthia Diep, Tiantian Mao, Li Huang, Robert Merrill, Zhouwen Zhang, Youjian Peng
Article Number: 14
Published online on: 11 November 2025

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Article Open Access

C‑terminal HSP90 inhibitor NCT‑58 impairs the cancer stem‑like phenotype and enhances chemotherapy efficacy in TNBC

Eunsun Jung, Yoon-Jae Kim, Kyoungmin Lee, Seojin Jang, Soeun Park, Eunhye Oh, Minsu Park, Seongjae Kim, Dongmi Ko, Yong Koo Kang, Kee Dal Nam, Lee Farrand, Cong-Truong Nguyen, Minh Thanh La, Jihyae Ann, Jeewoo Lee, Ji Young Kim, Jae Hong Seo
Article Number: 13
Published online on: 11 November 2025

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Correction Open Access

[Corrigendum] Compound 225# inhibits the proliferation of human colorectal cancer cells by promoting cell cycle arrest and apoptosis induction

Xiaoxue Zhang, Liujun He, Yong Li, Yifei Qiu, Wujing Hu, Wanying Lu, Huihui Du, Donglin Yang
Article Number: 12
Published online on: 06 November 2025

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Review Open Access

Immune system, inflammatory response, and regulated cell death in breast cancer research (Review)

Guangyao Li, Binghui Jin, Jialin Zhou, Shifeng Fang, Zhe Fan
Article Number: 11
Published online on: 05 November 2025

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Retraction Open Access

[Retracted] Uvangoletin induces mitochondria‑mediated apoptosis in HL‑60 cells in vitro and in vivo without adverse reactions of myelosuppression, leucopenia and gastrointestinal tract disturbances

Zhuanzhen Zheng, Zhenhua Qiao, Rong Gong, Yalin Wang, Yiqun Zhang, Yanping Ma, Li Zhang, Yujin Lu, Bo Jiang, Guoxia Li, Chunxia Dong, Wenliang Chen
Article Number: 10
Published online on: 03 November 2025

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Article Open Access

Characterization of the anticancer effect of mebendazole and its interaction with standard cytotoxic drugs in patient tumor cells ex vivo and in an in vivo mouse model

Sharmineh Mansoori, Kristin Blom, Claes Andersson, Mårten Fryknäs, Rolf Larsson, Peter Nygren
Article Number: 9
Published online on: 31 October 2025

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Correction Open Access

[Corrigendum] Gemcitabine combined with an engineered oncolytic vaccinia virus exhibits a synergistic suppressive effect on the tumor growth of pancreatic cancer

Wanyuan Chen, Weimin Fan, Guoqing Ru, Fang Huang, Xiaming Lu, Xin Zhang, Xiaozhou Mou, Shibing Wang
Article Number: 8
Published online on: 30 October 2025

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Article Open Access

CD44 knockdown and TGF‑β inhibition modulate cell proliferation and invasion in claudin‑low breast cancer cells

Ryoichi Matsunuma, Kazuo Kinoshita, Sae Imada, Shoko Sato, Ryosuke Hayami, Michiko Tsuneizumi
Article Number: 7
Published online on: 30 October 2025

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Retraction Open Access

[Retracted] MicroRNA‑302a targets GAB2 to suppress cell proliferation, migration and invasion of glioma

Jiuhong Ma, Jia Yu, Jingmei Liu, Xing Yang, Miao Lou, Jinghui Liu, Fuqiang Feng, Peigang Ji, Liang Wang
Article Number: 6
Published online on: 27 October 2025

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Article Open Access

LRRC59 inhibits perk pathway‑induced apoptosis and promotes cell proliferation, migration and invasion in colorectal cancer cells

Xingdong Hou, Yuting Wang, Yuzhuo Chen, Peiyan Zhong, Guangzhi Wang, Baicheng Li, Bowei Lu, Hanyu Jiang, Shili Ning
Article Number: 5
Published online on: 23 October 2025

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Article Open Access

Comparative analysis of the efficacy and safety of antibody‑drug conjugates, radionuclide‑drug conjugates and their combination targeting claudin 18.2 in gastric cancer treatment

Huan Du, Xiao-Fei Hao, Bin-Wei Lin, Yu Zhang, Luo Rui, Jing Wang, Ming-Ming Tang, De-Cai Wang, Yi-Han Zhu, Jie Li, Tang-Zhi Dai, Yuchuan Yang, Xia Yang, Xiaobo Du
Article Number: 4
Published online on: 22 October 2025

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Expression of Concern Open Access

[Expression of Concern] CDKN3 is an independent prognostic factor and promotes ovarian carcinoma cell proliferation in ovarian cancer

Tianren Li, Hui Xue, Yi Guo, Kejun Guo
Article Number: 3
Published online on: 16 October 2025

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Review Open Access

Platelet‑circulating tumor cell crosstalk: A pivotal target in cancer diagnosis and therapy (Review)

Lifang Zhang, Ye Yuan, Yan Deng, Lin Wang, Fenghua Chen
Article Number: 2
Published online on: 15 October 2025

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Expression of Concern Open Access

[Expression of Concern] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 1
Published online on: 14 October 2025

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February-2026 Volume 55 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells

Liangliang Jin, Li Wei, Junrui Hua, Rong Zhang, Jiaxin Chen, Jinpeng He, Yanli Yang
Article Number: 30
Published online on: 04 December 2025

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Review

Beyond eradication: Therapeutic reprogramming strategies for cancer normalization (Review)

Aliasgar Shahiwala
Article Number: 29
Published online on: 04 December 2025

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Article Open Access

Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy

Rui Zheng, Yusi Liu, Sen Zhou, Guimei Liu, Xiaobin Liu, Yiyuan Yang, Yufu Zhang
Article Number: 28
Published online on: 04 December 2025

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Retraction Open Access

[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Article Number: 27
Published online on: 04 December 2025

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Article Open Access

Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma

Yuto Kitano, Tomoharu Miyashita, Takeo Shimasaki, Isamu Makino, Yoshio Endo, Yasuhiko Yamamoto, Noriyuki Inaki, Shintaro Yagi
Article Number: 26
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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