Journal Articles

Preservation of fertility in patients with cancer (Review)

Sofía Del‑Pozo‑Lérida, Cristina Salvador, Fina Martínez‑Soler, Avelina Tortosa, Manuel Perucho, Pepita Giménez‑Bonafé

Pages: 2607-2614 Published online on: 14 March 2019

Survivin overexpression in head and neck squamous cell carcinomas as a new therapeutic target (Review)

M. A. Frassanito, I. Saltarella, A. Vinella, L. Lo Muzio, G. Pannone, R. Fumarulo, A. Vacca, M. A. Mariggiò

Pages: 2615-2624 Published online on: 21 March 2019

Role of natural killer cells for immunotherapy in chronic myeloid leukemia (Review)

Hye‑Rim Lee, Kwang‑Hyun Baek

Pages: 2625-2635 Published online on: 13 March 2019
Open Access

The PI3K inhibitor buparlisib suppresses osteoclast formation and tumour cell growth in bone metastasis of lung cancer, as evidenced by multimodality molecular imaging

Shengfei Wang, Xiaomin Niu, Xiao Bao, Qin Wang, Jianping Zhang, Shun Lu, Yongjun Wang, Ling Xu, Mingwei Wang, Jie Zhang

Pages: 2636-2646 Published online on: 20 March 2019
Open Access

MicroRNA-216a suppresses the proliferation and migration of human breast cancer cells via the Wnt/β-catenin signaling pathway

Qing Xie, Shuai Wang, Yue Zhao, Zhenchao Zhang, Chuan Qin, Xianjun Yang

Pages: 2647-2656 Published online on: 07 March 2019
Open Access

PARG regulates the proliferation and differentiation of DCs and T cells via PARP/NF‑κB in tumour metastases of colon carcinoma

Jie‑Qiong Wang, Yi Tang, Qing‑Shu Li, Ming Xiao, Ming Li, Yong‑Tao Sheng, Yi Yang, Ya‑Lan Wang

Pages: 2657-2666 Published online on: 07 March 2019
Open Access

Targeting P16INK4A in uterine serous carcinoma through inhibition of histone demethylation

Zhen Xiao, Yingying He, Chongya Liu, Lin Xiang, Jingyan Yi, Min Wang, Tingting Shen, Lanlin Shen, Yijue Xue, Hong Shi, Pixu Liu

Pages: 2667-2678 Published online on: 14 March 2019
Open Access

CD1d highly expressed on DCs reduces lung tumor burden by enhancing antitumor immunity

Yifan Li, Chujun Zhao, Jiajing Liu, Zhou Lu, Mingfang Lu, Jie Gu, Ronghua Liu

Pages: 2679-2688 Published online on: 28 February 2019
Open Access

Combination of phospholipase Cε knockdown with GANT61 sensitizes castration‑resistant prostate cancer cells to enzalutamide by suppressing the androgen receptor signaling pathway

Wei Sun, Luo Li, Zhongbo Du, Zhen Quan, Mengjuan Yuan, Honglin Cheng, Yingying Gao, Chunli Luo, Xiaohou Wu

Pages: 2689-2702 Published online on: 07 March 2019
Open Access

Hyperbaric oxygen increases glioma cell sensitivity to antitumor treatment with a novel isothiourea derivative in vitro

Katarzyna Zembrzuska, Robert P. Ostrowski, Ewa Matyja

Pages: 2703-2716 Published online on: 14 March 2019
Open Access

Rab1A promotes proliferation and migration abilities via regulation of the HER2/AKT-independent mTOR/S6K1 pathway in colorectal cancer

Zhengwu Cheng, Xinyu Shao, Menglin Xu, Junfeng Wang, Xiaoyi Kuai, Liping Zhang, Jian Wu, Chunli Zhou, Jiading Mao

Pages: 2717-2728 Published online on: 15 March 2019
Open Access

miR-363 acts as a tumor suppressor in osteosarcoma cells by inhibiting PDZD2

Fan He, Long Fang, Qingshui Yin

Pages: 2729-2738 Published online on: 19 March 2019
Open Access

Overexpression of IC53d promotes the proliferation of gastric cancer cells by activating the AKT/GSK3β/cyclin D1 signaling pathway

Jian‑Xian Lin, Xin‑Sheng Xie, Xiong‑Feng Weng, Sheng‑Liang Qiu, Jian‑Wei Xie, Jia‑Bin Wang, Jun Lu, Qi‑Yue Chen, Long‑Long Cao, Mi Lin, Ru‑Hong Tu, Ping Li, Chang‑Ming Huang, Chao‑Hui Zheng

Pages: 2739-2752 Published online on: 05 March 2019
Open Access

LATS2 inhibits cell proliferation and metastasis through the Hippo signaling pathway in glioma

Chengyong Guo, Chaohui Liang, Jipeng Yang, Hongchao Hu, Bo Fan, Xin Liu

Pages: 2753-2761 Published online on: 14 March 2019
Open Access

Genome‑wide DNA methylation profile of thymomas and potential epigenetic regulation of thymoma subtypes

Yalan Bi, Yunxiao Meng, Yuchen Niu, Shanqing Li, Hongsheng Liu, Jia He, Ye Zhang, Naixin Liang, Lei Liu, Xinxin Mao, Jie Yan, Bo Long, Zhiyong Liang, Zhihong Wu

Pages: 2762-2774 Published online on: 28 February 2019
Open Access

Interaction with tumor‑associated macrophages promotes PRL‑3‑induced invasion of colorectal cancer cells via MAPK pathway‑induced EMT and NF‑κB signaling‑induced angiogenesis

Tao Zhang, Lu Liu, Wei Lai, Yujie Zeng, Heyang Xu, Qiusheng Lan, Pengwei Su, Zhonghua Chu

Pages: 2790-2802 Published online on: 07 March 2019
Open Access

Non‑covalent proteasome inhibitor PI‑1840 induces apoptosis and autophagy in osteosarcoma cells

Yuxi Chen, Hongjun Chen, Hui Xie, Shaohui Yuan, Chuanbo Gao, Lei Yu, Zhenggang Bi

Pages: 2803-2817 Published online on: 01 March 2019
Open Access

Recombinant adenoviruses expressing apoptin suppress the growth of MCF‑7 breast cancer cells and affect cell autophagy

Shuang Chen, Yi‑Quan Li, Xun‑Zhe Yin, Shan‑Zhi Li, Yi‑Long Zhu, Yuan‑Yuan Fan, Wen‑Jie Li, Ying‑Li Cui, Jin Zhao, Xiao Li, Qing‑Gao Zhang, Ning‑Yi Jin

Pages: 2818-2832 Published online on: 18 March 2019
Open Access

PD‑L1 promotes head and neck squamous cell carcinoma cell growth through mTOR signaling

Anyuan Zheng, Fen Li, Fuhai Chen, Jingjing Zuo, Lei Wang, Yongping Wang, Shiming Chen, Bokui Xiao, Zezhang Tao

Pages: 2833-2843 Published online on: 07 March 2019
Open Access

PLCε promotes urinary bladder cancer cells proliferation through STAT3/LDHA pathway‑mediated glycolysis

Honglin Cheng, Yanni Hao, Yingying Gao, Yunfeng He, Chunli Luo, Wei Sun, Mengjuan Yuan, Xiaohou Wu

Pages: 2844-2854 Published online on: 13 March 2019
Open Access

Diagnostic and prognostic value of mRNA expression of phospholipase C β family genes in hepatitis B virus‑associated hepatocellular carcinoma

Xiangkun Wang, Ketuan Huang, Xianmin Zeng, Zhengqian Liu, Xiwen Liao, Chengkun Yang, Tingdong Yu, Chuangye Han, Guangzhi Zhu, Wei Qin, Tao Peng

Pages: 2855-2875 Published online on: 14 March 2019
Open Access

Genome-scale integrated analysis to identify prospective molecular mechanisms and therapeutic targets in isocitrate dehydrogenase 2 R140Q-mutated acute myeloid leukemia

Rui Huang, Xiwen Liao, Jing Li, Jiemin Wei, Xiayun Su, Xiaoxuan Lai, Beicai Liu, Fangxiao Zhu, Yumei Huang, Qiaochuan Li

Pages: 2876-2888 Published online on: 18 March 2019

Y‑box‑binding protein 1 inhibits apoptosis and upregulates EGFR in colon cancer

Sachiko Nagasu, Tomoya Sudo, Tetsushi Kinugasa, Takatou Yomoda, Kenji Fujiyoshi, Takahiro Shigaki, Yoshito Akagi

Pages: 2889-2896 Published online on: 28 February 2019

miR‑146a regulates the function of Th17 cell differentiation to modulate cervical cancer cell growth and apoptosis through NF‑κB signaling by targeting TRAF6

Tian Li, Mengxiong Li, Chengfang Xu, Xiaoyu Xu, Jie Ding, Li Cheng, Rongying Ou

Pages: 2897-2908 Published online on: 07 March 2019

Higher tumor mass and lower adipose mass are associated with colon‑26 adenocarcinoma‑induced cachexia in male, female and ovariectomized mice

Taylor Banh, Deena Snoke, Rachel M. Cole, Austin Angelotti, Patrick M. Schnell, Martha A. Belury

Pages: 2909-2918 Published online on: 20 March 2019

Wound fluid enhances cancer cell proliferation via activation of STAT3 signal pathway in vitro

Agmal Scherzad, Thomas Gehrke, Till Meyer, Pascal Ickrath, Maximilian Bregenzer, Rafael Eiter, Rudolf Hagen, Norbert Kleinsasser, Stephan Hackenberg

Pages: 2919-2926 Published online on: 07 March 2019

5‑Azacytidine treatment results in nuclear exclusion of DNA methyltransferase‑1, as well as reduced proliferation and invasion in human cytomegalovirus‑infected glioblastoma cells

Atosa Estekizadeh, Natalia Landázuri, Mattia Russel Pantalone, Belghis Davoudi, Li‑Fu Hu, Imran Nawaz, Giuseppe Stragliotto, Tomas J. Ekström, Afsar Rahbar

Pages: 2927-2936 Published online on: 18 March 2019

Timosaponin A‑III induces autophagy of T‑cell acute lymphoblastic leukemia Jurkat cells via inhibition of the PI3K/Akt/mTOR pathway

Hong Wang, Rui Dong, Wen‑Wen Fan, Xing‑Chang Zheng, Ai‑Min Li, Wen‑Di Wang

Pages: 2937-2944 Published online on: 15 March 2019

LncRNA‑AB209371 promotes the epithelial‑mesenchymal transition of hepatocellular carcinoma cells

Chaocheng Xiao, Xinqiang Wan, Haiyang Yu, Xiaotong Chen, Xiangxiang Shan, Yufeng Miao, Rengen Fan, Wenzhang Cha

Pages: 2957-2966 Published online on: 07 March 2019

Downregulation of estrogen receptor β inhibits lung adenocarcinoma cell growth

Wenjuan Chen, Bo Xin, Hailin Pang, Le Han, Weiwei Shen, Zheng Zhao, Lian Duan, Peipei Cao, Lili Liu, Helong Zhang

Pages: 2967-2974 Published online on: 05 March 2019

Astragaloside IV inhibits the invasion and metastasis of SiHa cervical cancer cells via the TGF‑β1‑mediated PI3K and MAPK pathways

Lei Zhang, Jie Zhou, Xiaokang Qin, Huaming Huang, Chao Nie

Pages: 2975-2986 Published online on: 13 March 2019

Antitumor effects of hsa‑miR661‑3p on non‑small cell lung cancer in vivo and in vitro

Jingjing Lu, Xia Gu, Fanglei Liu, Zhuanghua Rui, Ming Liu, Liming Zhao

Pages: 2987-2996 Published online on: 21 March 2019

LASS2 inhibits proliferation and induces apoptosis in HepG2 cells by affecting mitochondrial dynamics, the cell cycle and the nuclear factor‑κB pathways

Yan Yang, Xiaoli Yang, Lin Li, Gangyi Yang, Xuhong Ouyang, Jialin Xiang, Tao Zhang, Xun Min

Pages: 3005-3014 Published online on: 13 March 2019

Downregulation of cytokeratin 18 enhances BCRP-mediated multidrug resistance through induction of epithelial-mesenchymal transition and predicts poor prognosis in breast cancer

Ruizan Shi, Chang Wang, Naijie Fu, Linhong Liu, Diying Zhu, Zehui Wei, Huifeng Zhang, Jianfeng Xing, Yan Wang

Pages: 3015-3026 Published online on: 15 March 2019

Construction of ceRNA networks reveals differences between distal and proximal colon cancers

Wenwei Qian, Yifei Feng, Jie Li, Wen Peng, Qiou Gu, Zhiyuan Zhang, Dongjian Ji, Qingyuan Wang, Dongsheng Zhang, Yueming Sun

Pages: 3027-3040 Published online on: 21 March 2019

Predictive value of the ratio of 8‑hydroxydeoxyguanosine levels between cancerous and normal tissues in patients with stage II/III colorectal cancer

Hiroshi Kitagawa, Yoshihiko Kitajima, Keita Kai, Sho Komukai, Tomokazu Tanaka, Yasuo Koga, Tatsuya Manabe, Hirokazu Noshirο

Pages: 3041-3050 Published online on: 22 March 2019

Hepatitis C virus nonstructural 5A protein inhibits the starvation‑induced apoptosis of hepatoblastoma cells by increasing Beclin 1 expression

Min Quan, Shunai Liu, Li Zhou, Shenghu Feng, Yu Zhang, Jun Cheng

Pages: 3051-3059 Published online on: 13 March 2019

Tropomodulin 3 promotes liver cancer progression by activating the MAPK/ERK signaling pathway

Canguang Jin, Zhikang Chen, Wei Shi, Qi Lian

Pages: 3060-3068 Published online on: 07 March 2019

Songorine suppresses cell growth and metastasis in epithelial ovarian cancer via the Bcl‑2/Bax and GSK3β/β‑catenin signaling pathways

Hongxia Zhang, Ruifeng Dong, Ping Zhang, Yankui Wang

Pages: 3069-3079 Published online on: 15 March 2019

Proteins of the Wnt signaling pathway as targets for the regulation of CD133+ cancer stem cells in glioblastoma

Valery Shevchenko, Nataliya Arnotskaya, Maria Korneyko, Sergry Zaytsev, Yuriy Khotimchenko, Hary Sharma, Igor Bryukhovetskiy

Pages: 3080-3088 Published online on: 05 March 2019

Transcriptome‑wide piRNA profiling in human gastric cancer

Xiandong Lin, Yan Xia, Dan Hu, Qiao Mao, Zongyang Yu, Hejun Zhang, Chao Li, Gang Chen, Fen Liu, Weifeng Zhu, Yi Shi, Huihao Zhang, Jianming Zheng, Tao Sun, Jianying Xu, Herta H. Chao, Xiongwei Zheng, Xingguang Luο

Pages: 3089-3099 Published online on: 18 March 2019

Microwave hyperthermia enhances the sensitivity of lung cancer cells to gemcitabine through reactive oxygen species‑induced autophagic death

Yang Yang, Chun‑Li Yang, Zhen‑Jiang Zhao, Xiao‑Xiao Zuo, Tian‑Song Liang, Ya Yang, Sheng‑Lin Ma, Dao‑Ke Yang

Pages: 3100-3110 Published online on: 22 March 2019

Transcribed ultraconserved region Uc.63+ promotes resistance to cisplatin through regulation of androgen receptor signaling in bladder cancer

Yohei Sekino, Naoya Sakamoto, Akira Ishikawa, Ririno Honma, Yoshinori Shigematsu, Tetsutaro Hayashi, Kazuhiro Sentani, Naohide Oue, Jun Teishima, Akio Matsubara, Wataru Yasui

Pages: 3111-3118 Published online on: 28 February 2019

Induction of HSP27 and HSP70 by constitutive overexpression of Redd1 confers resistance of lung cancer cells to ionizing radiation

Hyeon‑Ok Jin, Sung‑Eun Hong, Ji‑Young Kim, Mi‑Ri Kim, Yoon Hwan Chang, Young Jun Hong, Jin Kyung Lee, In‑Chul Park

Pages: 3119-3126 Published online on: 28 February 2019

Selected nitrostyrene compounds demonstrate potent activity in chronic lymphocytic leukaemia cells, including those with poor prognostic markers

S. A. Bright, A. J. Byrne, E. Vandenberghe, P. V. Browne, A. M. Mcelligott, M. J. Meegan, D. C. Williams

Pages: 3127-3136 Published online on: 15 March 2019

microRNA‑485 inhibits the malignant behaviors of retinoblastoma by directly targeting Wnt3a

Xueman Lyu, Ling Wang, Jia Lu, Hong Zhang, Lina Wang

Pages: 3137-3147 Published online on: 13 March 2019
Open Access

[Corrigendum] miR-9 regulates the multidrug resistance of chronic myelogenous leukemia by targeting ABCB1

Yan Li, Lifen Zhao, Nana Li, Yuan Miao, Huimin Zhou, Li Jia

Pages: 3148-3148 Published online on: 13 March 2019
Open Access

[Corrigendum] NHE1 is upregulated in gastric cancer and regulates gastric cancer cell proliferation, migration and invasion

Rui Xie, Haibo Wang, Hai Jin, Guorong Wen, Biguang Tuo, Jingyu Xu

Pages: 3149-3149 Published online on: 07 March 2019
Journal Cover

May-2019
Volume 41 Issue 5

Print ISSN: 1021-335X
Online ISSN: 1791-2431

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