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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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International Journal of Molecular Medicine

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
August 2004 Volume 14 Issue 2

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Journal Metrics

Impact Factor: 8.5

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article

Cross talk between COX-2 inhibitor and hyaluronic acid in osteoarthritic chondrocytes

Toshiaki Takahashi, Yoshiki Uemura, Hirokuni Taguchi, Yasuhiro Ogawa, Shoji Yoshida, Michio Toda, Toshihiro Kobayashi, Harumichi Seguchi, Toshikazu Tani
Pages: 139-144
Published online on: 01 August 2004

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Article

Peptide nucleic acid-DNA decoy chimeras targeting NF-κB transcription factors: Induction of apoptosis in human primary osteoclasts

Letizia Penolazzi, Monica Borgatti, Elisabetta Lambertini, Carlo Mischiati, Alessia Finotti, Alessandra Romanelli, Michele Saviano, Carlo Pedone, Roberta Piva, Roberto Gambari
Pages: 145-152
Published online on: 01 August 2004

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Article

Targeting Ku protein for sensitizing of breast cancer cells to DNA-damage

Li Zhang, Sunghan Yoo, Anatoly Dritschilo, Igor Belyaev, Viatcheslav Soldatenkov
Pages: 153-159
Published online on: 01 August 2004

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Article

Phospholipase-C β1 is predominantely expressed in the granular layer of rat cerebellar cortex

Marco Vitale, Rita Rezzani, Giuliana Gobbi, Cristina Ponti, Alessandro Matteucci, Andrea Cacchioli, Alessandra Ruggeri, Lucio Cocco
Pages: 161-164
Published online on: 01 August 2004

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Article

Effect of ghrelin on the apoptotic deletion rate of different types of cells cultured in vitro

Anna S. Belloni, Carlo Macchi, Piera Rebuffat, Maria Teresa Conconi, Ludwik K. Malendowicz, Pier Paolo Parnigotto, Gastone G. Nussdorfer
Pages: 165-167
Published online on: 01 August 2004

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Article

Ubiquitous p63 expression in human esophageal squamous cell carcinoma

Tadashi Hara, Hiroshi Kijima, Soichiro Yamamoto, Takahiro Kenmochi, Yosifumi Kise, Hikaru Tanaka, Osamu Chino, Hideo Shimada, Kensuke Takazawa, Makiko Tanaka, Sadaki Inokuchi, Hiroyasu Makuuchi
Pages: 169-173
Published online on: 01 August 2004

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Article

The Na+/H+ exchange inhibitor HOE642 prevents stress-induced epithelial barrier dysfunction

Peter Nowak, Roman Blaheta, Alina Schuller, Jindrich Cinatl, Gerhard Wimmer-Greinecker, Anton Moritz, Martin Scholz
Pages: 175-178
Published online on: 01 August 2004

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Article

Expression of CD34-positive sinusoidal endothelial cells in patients with HBV-associated chronic liver diseases

Shigeru Ohmori, Katsuya Shiraki, Kazushi Sugimoto, Yutaka Yamanaka, Yumi Yamaguchi, Yukiko Saitou, Katsuhiko Fujikawa, Kazumoto Murata, Takeshi Nakano
Pages: 179-184
Published online on: 01 August 2004

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Article

The relationship of the human glutathione S-transferase P1 polymorphism and chemotherapeutic sensitivity in head and neck squamous carcinoma

Shinobu Kimura, Yukari Imagawa, Kenichi Satake, Mamoru Tsukuda
Pages: 185-189
Published online on: 01 August 2004

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Article

Reduced intestinal inflammation induced by dextran sodium sulfate in interleukin-6-deficient mice

Yuji Naito, Tomohisa Takagi, Kazuhiko Uchiyama, Masaaki Kuroda, Satoshi Kokura, Hiroshi Ichikawa, Rie Yanagisawa, Ken-Ichiro Inoue, Hirohisa Takano, Masahiko Satoh, Norimasa Yoshida, Takeshi Okanoue, Toshikazu Yoshikawa
Pages: 191-196
Published online on: 01 August 2004

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Article

Lysosomal dysfunction on hydrogen peroxide-induced apoptosis of osteoarthritic chondrocytes

Toshiaki Takahashi, Ken-Ichi Kitaoka, Yasuhiro Ogawa, Toshihiro Kobayashi, Harumichi Seguchi, Toshikazu Tani, Shoji Yoshida
Pages: 197-200
Published online on: 01 August 2004

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Article

Development of pancreatic islets in pancreatic polypeptide-overexpressing mice

Hideki Yuzuriha, Akio Inui, Akihiro Asakawa, Naohiko Ueno, Ruka Sakamaki, Naotaka Shinfuku, Masato Kasuga, Mineko Fujimiya
Pages: 201-205
Published online on: 01 August 2004

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Article

Induction of polycystic ovary by testosterone in immature female rats: Modulation of apoptosis and attenuation of glucose/insulin ratio

R. Beloosesky, R. Gold, B. Almog, R. Sasson, A. Dantes, A. Land-Bracha, L. Hirsh, J. Itskovitz-Eldor, J. B. Lessing, R. Homburg, A. Amsterdam
Pages: 207-215
Published online on: 01 August 2004

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Article

Identification of genes differentially expressed in breast cancer cell line SKBR3: Potential identification of new prognostic biomarkers

Marianne Leirdal, Mohsen Shadidy, Øystein Røsok, Mouldy Sioud
Pages: 217-222
Published online on: 01 August 2004

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Article

Cellular analysis of growth suppression induced by the Notch ligands, Delta-1 and Jagged-1 in two myeloid leukemia cell lines

Mai Murata-Ohsawa, Shuji Tohda, Nobuo Nara
Pages: 223-226
Published online on: 01 August 2004

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Article

Induction of apoptotic cell death by mycelium extracts of Phellinus linteus in human neuroblastoma cells

Yung Hyun Choi, Man Kyu Huh, Chung-Ho Ryu, Byung Tae Choi, Young-Kee Jeong
Pages: 227-232
Published online on: 01 August 2004

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Article

Substrate specificity of Xenopus matrix metalloproteinase stromelysin-3

Tosikazu Amano, Liezhen Fu, Shelley Sahu, Meghan Markey, Yun-Bo Shi
Pages: 233-239
Published online on: 01 August 2004

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Article

Role of caspase in CD80 expression of superantigen-stimulated monocytes

Fumiaki Shinohara, Keiko Sato, Maiko Suzuki, Haruhiko Takada, Seishi Echigo, Hidemi Rikiishi
Pages: 241-246
Published online on: 01 August 2004

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Article

Dynamics and regional distribution of c-fos protein expression in rat brain after a closed head injury

Andrea Czigner, András Mihály, Orsolya Farkas, András Büki, Beáta Krisztin-Péva, Endre Dobó, Pál Barzó
Pages: 247-252
Published online on: 01 August 2004

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Article

Induction of apoptosis by ar-turmerone on various cell lines

Mingjie Ji, Jaesue Choi, Jeongnyeo Lee, Yongkyu Lee
Pages: 253-256
Published online on: 01 August 2004

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Article

Development and characterization of five cell models for chemoresistance studies of human ovarian carcinoma

Li Li, Yingzi Luan, Gangduo Wang, Bujian Tang, Danrong Li, Wei Zhang, Xiping Li, Jinshun Zhao, Hong Ding, Eddie Reed, Qingdi Q. Li
Pages: 257-264
Published online on: 01 August 2004

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Article

Early graft hemodynamics in living related liver transplantation evaluated by Doppler ultrasonography

Shigeo Nakanishi, Katsuya Shiraki, Kouji Yamamoto, Yukiko Saitou, Shigeru Ohmori, Takeshi Nakano, Shugo Mizuno, Masami Tabata, Kentarou Yamagiwa, Hajime Yokoi, Shuji Isaji, Shinji Uemoto
Pages: 265-269
Published online on: 01 August 2004

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Article

Adenoviral-mediated transfer of p53 gene enhances TRAIL-induced apoptosis in human hepatocellular carcinoma cells

Hidekazu Inoue, Katsuya Shiraki, Kazumoto Murata, Kazushi Sugimoto, Tomoyuki Kawakita, Yumi Yamaguchi, Yukiko Saitou, Naoyuki Enokimura, Norihiko Yamamoto, Yutaka Yamanaka, Takeshi Nakano
Pages: 271-275
Published online on: 01 August 2004

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Article

Role of regucalcin in liver nuclear function: Binding of regucalcin to nuclear protein or DNA and modulation of tumor-related gene expression

Yoshinori Tsurusaki, Masayoshi Yamaguchi
Pages: 277-281
Published online on: 01 August 2004

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Article

Influence of DMBA-induced mammary cancer on the liver CPT I, mit HMG-CoA synthase and PPARα mRNA expression in rats fed a low or high corn oil diet

Raquel Moral, Montserrat Solanas, Eva Mónica Manzanares, Diego Haro, Eduard Escrich
Pages: 283-287
Published online on: 01 August 2004

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Article

CpG methylation of the ERα# and ERβ genes in breast cancer

Sun Jung Kim, Tae Won Kim, Su-Young Lee, Sang-Jae Park, Hee Sung Kim, Ki-Wook Chung, Eun Sook Lee, Han-Sung Kang
Pages: 289-293
Published online on: 01 August 2004

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Article

Production and efficacy of a dendritic cell-based therapeutic vaccine for murine chronic hepatitis B virus carrierer

S. M.F. Akbar, Shinya Furukawa, Aki Hasebe, Norio Horiike, Kojiro Michitaka, Morikazu Onji
Pages: 295-299
Published online on: 01 August 2004

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Article

Distribution of HBV genotypes and mutants among hepatitis B infected patients from northern Poland

Krzysztof Piotr Bielawski, Aleksandra Dybikowska, Urszula Lisowska-Charmuszko, Piotr Stalke, Katarzyna Gregorowicz, Hanna Trocha, Anna Podhajska
Pages: 301-304
Published online on: 01 August 2004

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Article

Differentiation of HL-60 myeloid leukemia cells induced by all-trans retinoic acid is enhanced in combination with caffeic acid

Renata Veselská, Karel Zitterbart, Jan Auer, Jakub Neradil
Pages: 305-310
Published online on: 01 August 2004

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Review

Hematological findings in SARS patients and possible mechanisms (Review)

Mo Yang, Chi Kong Li, Karen Li, K. L.E. Hon, M. H.L. Ng, Paul K.S. Chan, Tai Fai Fok
Pages: 311-315
Published online on: 01 August 2004

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Article

The pro- and anti-inflammatory markers in patients with acute myocardial infarction and chronic stable angina

Wojciech Wojakowski, Katarzyna Maslankiewicz, Andrzej Ochala, Rafal Wyderka, Izabela Zuk-Popiolek, Zbigniew Flak, Iwona Mroz, Michal Tendera
Pages: 317-322
Published online on: 01 August 2004

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Article

Per os administration of 5-fluorocytosine is effective in the regression of CD-expressing liver metastases in rats

Adolfo Gavelli, Patrick Baqué, Nicole Brossettej, André Bourgeon, Pascal Staccini, Bernard Rossi, Valérie Pierrefite-Carle
Pages: 323-325
Published online on: 01 August 2004

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Article

Identification and characterization of human FCHO2 and mouse Fcho2 genes in silico

Masuko Katoh, Masaru Katoh
Pages: 327-331
Published online on: 01 August 2004

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Article

Identification and characterization of ARHGAP24 and ARHGAP25 genes in silico

Masuko Katoh, Masaru Katoh
Pages: 333-338
Published online on: 01 August 2004

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Journal Cover
October-2026 Volume 58 Issue 4

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Journal Metrics

Impact Factor: 8.5

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Role of adipocytes and their derived extracellular vesicles in the progression, diagnosis and treatment of liver diseases (Review)

Kangrong Li, Muhammad Zubair, Yongmin Yan, Jiahao Xu
Article Number: 293
Published online on: 20 August 2026

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Correction Open Access

[Corrigendum] EBM84 attenuates airway inflammation and mucus hypersecretion in an ovalbumin‑induced murine model of asthma

In Sik Shin, Mee Young Lee, Woo Young Jeon, Na Ra Shin, Chang Seob Seo, Hyekyung Ha
Article Number: 292
Published online on: 20 August 2026

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Review Open Access

Decoding fibroblast activation: Transcriptional networks in hepatic stellate cells and across fibrotic organs (Review)

Denita Charoenthanakitkul, Chaiyaboot Ariyachet
Article Number: 291
Published online on: 20 August 2026

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Review Open Access

Inflammatory bowel disease treatment: Mechanisms to clinical translation (Review)

Siqi Tang, Guoyou Gou, Youjia Liu, Fang Wang, Feihong Shu, Ya Deng, Ting Zhang, Jingyu Xu, Rui Xie
Article Number: 290
Published online on: 18 August 2026

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Review Open Access

Redox biology in PCOS: Biomarkers, mechanistic networks, and targeted interventions (Review)

Yuena Qiu, Xiaojing Guo, Jie An
Article Number: 289
Published online on: 18 August 2026

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Review Open Access

Glucose metabolism in osteoporosis: A potential therapeutic target (Review)

Shengyao Peng, Zhuo Yao, Junzhe Guo, Chi Zhang, Keda Yang, Lin Tao
Article Number: 288
Published online on: 17 August 2026

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Retraction Open Access

[Retracted] Engulfment of platelets delays endothelial cell aging via girdin and its phosphorylation

Yong Lan, Yongjun Li, Dajun Li, Peng Li, Jiyang Wang, Yongpeng Diao, Guodong Ye, Yangfang Li
Article Number: 287
Published online on: 17 August 2026

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Article Open Access

α‑Cyperone targets the PAK1‑JNK/NF‑κB axis to modulate dendritic cells maturation and Th2/Th9 differentiation in an asthma model

Hang Hu, Xing Wang, Linlin Guo, Ziling Zeng, Hongmei Tang, Yun Zhang, Jiayao Duan, Kaijin Wang
Article Number: 286
Published online on: 14 August 2026

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Article Open Access

Early high‑frequency spinal cord stimulation modulates the ROS/p38 MAPK/NF‑κB and CXCL10/CXCR3 pathways to alleviate neuropathic pain and promote spinal cord injury repair

Sitong Su, Tao Liu, Honghui Lei, Yang Yu, Caizhi Ma, Xinglang Wang, Haoyuan Chen, Zebin Huang, Meiling Cheng, Tongtong Qian, Fangyong Wang
Article Number: 285
Published online on: 13 August 2026

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Review Open Access

Shared mechanisms of musculoskeletal dysfunction in type 2 diabetes mellitus: Insights into future therapeutic directions (Review)

Zhenhong He, Hanyu Li, Yuhan Luo, Yingying Yu, Siyu Li, Tao Zhang, Dingsu Bao
Article Number: 284
Published online on: 12 August 2026

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Expression of Concern Open Access

[Expression of Concern] Exogenous spermine attenuates diabetic kidney injury in rats by inhibiting AMPK/mTOR signaling pathway

Xinying Zhang, Li Zhang, Zhe Chen, Siwei Li, Bingbing Che, Ningning Wang, Junting Chen, Changqing Xu, Can Wei
Article Number: 283
Published online on: 12 August 2026

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Article Open Access

G protein‑coupled receptor kinase 4 governs early kidney development via STAT3 and Nhe3a

Linh Anna Trúc Vu, Julian Gerhards, Lars D. Maerz, Martin D. Burkhalter, Melanie Philipp
Article Number: 282
Published online on: 11 August 2026

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Retraction Open Access

[Retracted] Resistant starch prevents tumorigenesis of dimethylhydrazine‑induced colon tumors via regulation of an ER stress‑mediated mitochondrial apoptosis pathway  

Qiuyu Wang, Peng Wang, Zhigang Xiao
Article Number: 281
Published online on: 10 August 2026

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Review Open Access

XBP1 signaling from tumor metabolic stress to myeloid driven immunotherapy resistance (Review)

Ziwei Chen, Jiaqi Wu, Wenxi Liu, Jie Tan, Xiaochun Peng, Yanhua Zhang, Gai Liang
Article Number: 280
Published online on: 05 August 2026

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Review Open Access

Decoding miRNA‑146a: Mechanisms of action in cardiovascular diseases and endocrine metabolic disorders (Review)

Xiu Yang, Pengcheng Li, Hao Zhao
Article Number: 279
Published online on: 05 August 2026

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Review Open Access

Contribution of p38 MAPK in liver fibrosis: An overview of mechanisms, signaling pathways, and therapeutic targets (Review)

Xueqin Yang, Huarong Li, Hao Ye, Ting Wu, Fangyun Xu, Chao Hu, Chunlei Yu, Pian Ye
Article Number: 278
Published online on: 05 August 2026

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Correction Open Access

[Corrigendum] Peroxisome proliferator‑activated receptor α regulates acesulfame‑K‑induced NAFLD via hepatic PLCβ: Foe and friend

Peng-Yao Lin, Jia-Rong Xie, Tian-Chen Qian, Shi-Song Wang, Si-Yi Yu, Wen-Bo Shi, Ying Wang, Lu-Ze Cen, Qing-Jing Zhu, Yi-Yang Zheng, Hui Gao, Rong Fang, Zhao-Xia Xia, Ai-Ming Liu, Lei Xu
Article Number: 277
Published online on: 05 August 2026

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Review Open Access

Multi‑omics insights into uveitis: From mechanisms to precision medicine (Review)

Chengzhi Liu, Qiong Wu, Mingzhen Yuan, Mingyue Liu, Xinyu Wang, Jiaqi Shen, Xusheng Cao
Article Number: 276
Published online on: 03 August 2026

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Retraction Open Access

[Retracted] Effects of miRNA‑455 on cardiac hypertrophy induced by pressure overload

Chuntao Wu, Shimin Dong, Yongjun Li
Article Number: 275
Published online on: 03 August 2026

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Article Open Access

Energy stress activates AMPK to suppress ferroptosis in neurodegenerative proteinopathies

Yuanyuan Yong, Yuxin Hu, Qian Feng, Xiaogang Zhou, Lu Yu, Dalian Qin, Jianing Mi, Jianming Wu, Jianxin Liu, Anguo Wu
Article Number: 274
Published online on: 31 July 2026

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Article Open Access

Brazilin attenuates methylglyoxal‑induced endothelial injury by enhancing eIF5A hypusination and inhibiting the AMPK/mTOR‑mediated autophagy/apoptosis axis in vitro and in vivo

Yu Liang, Jinxiang Chen, Haiyang Li, Junjing Xiong, Jingcan You, Liqun Wang, Jianbo Wu, Youkun Zheng, Mao Luo
Article Number: 273
Published online on: 30 July 2026

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Review Open Access

Post‑translational modifications in atherosclerosis: Roles, mechanisms and therapeutic potential (Review)

Xiaoxiang Xu, Fei Ma, Wei Yu
Article Number: 272
Published online on: 30 July 2026

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Review Open Access

Role of extracellular matrix in liver fibrosis regression and regeneration (Review)

Yuanzhi Zhou, Zeyuan Qiang, Yang Duan, Jiwei Huang, Haichuan Wang
Article Number: 271
Published online on: 29 July 2026

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Correction Open Access

[Corrigendum] Circulating microRNA profiles and the identification of miR‑593 and miR‑511 which directly target the PROP1 gene in children with combined pituitary hormone deficiency

Yanyan Hu, Qian Wang, Zengmin Wang, Fengxue Wang, Xiaobo Guo, Guimei Li
Article Number: 270
Published online on: 29 July 2026

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Review Open Access

Unveiling the role of spatial transcriptomics in the analysis of the tumor immune microenvironment (Review)

Jialin Jiang, Xinyu Tu, Yi Cao, Qun Yan, Buqing Sai, Jian Ma
Article Number: 269
Published online on: 28 July 2026

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Expression of Concern Open Access

[Expression of Concern] Luteolin protects mice from severe acute pancreatitis by exerting HO‑1‑mediated anti‑inflammatory and antioxidant effects

Jie Xiong, Kezhou Wang, Chunxiao Yuan, Rong Xing, Jianbo Ni, Guoyong Hu, Fengling Chen, Xingpeng Wang
Article Number: 268
Published online on: 27 July 2026

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Article Open Access

circRNA_013145‑miR‑185‑5p‑RhoA axis: A novel mechanism in the pathophysiology of diabetes‑induced erectile dysfunction

Wenhan Huang, Xin Lv, Jiahua Qian, Yihao Chen, Yuhe Si, Jingwei Wang, Jianxiong Ma
Article Number: 267
Published online on: 24 July 2026

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Review Open Access

Gut‑liver‑kidney axis: A systems biology framework for understanding and treating chronic kidney disease (Review)

Jinyi Hou, Yaotan Li, Shijia Lin, Qingqing Liu, Huijuan Zheng, Weijing Liu, Yaoxian Wang, Liang Peng, Zhen Wang
Article Number: 266
Published online on: 23 July 2026

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Review Open Access

Effects of cuproptosis and its application in inflammatory bowel disease (Review)

Li Chen, Francis Atim Akanyibah, Jing Guan, Bing Pei, Bo Wang, Fei Mao
Article Number: 265
Published online on: 23 July 2026

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November-2026 Volume 58 Issue 5

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Journal Metrics

Impact Factor: 8.5

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

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