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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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International Journal of Molecular Medicine

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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
August 2004 Volume 14 Issue 2

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article

Cross talk between COX-2 inhibitor and hyaluronic acid in osteoarthritic chondrocytes

Toshiaki Takahashi, Yoshiki Uemura, Hirokuni Taguchi, Yasuhiro Ogawa, Shoji Yoshida, Michio Toda, Toshihiro Kobayashi, Harumichi Seguchi, Toshikazu Tani
Pages: 139-144
Published online on: 01 August 2004

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Article

Peptide nucleic acid-DNA decoy chimeras targeting NF-κB transcription factors: Induction of apoptosis in human primary osteoclasts

Letizia Penolazzi, Monica Borgatti, Elisabetta Lambertini, Carlo Mischiati, Alessia Finotti, Alessandra Romanelli, Michele Saviano, Carlo Pedone, Roberta Piva, Roberto Gambari
Pages: 145-152
Published online on: 01 August 2004

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Article

Targeting Ku protein for sensitizing of breast cancer cells to DNA-damage

Li Zhang, Sunghan Yoo, Anatoly Dritschilo, Igor Belyaev, Viatcheslav Soldatenkov
Pages: 153-159
Published online on: 01 August 2004

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Article

Phospholipase-C β1 is predominantely expressed in the granular layer of rat cerebellar cortex

Marco Vitale, Rita Rezzani, Giuliana Gobbi, Cristina Ponti, Alessandro Matteucci, Andrea Cacchioli, Alessandra Ruggeri, Lucio Cocco
Pages: 161-164
Published online on: 01 August 2004

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Article

Effect of ghrelin on the apoptotic deletion rate of different types of cells cultured in vitro

Anna S. Belloni, Carlo Macchi, Piera Rebuffat, Maria Teresa Conconi, Ludwik K. Malendowicz, Pier Paolo Parnigotto, Gastone G. Nussdorfer
Pages: 165-167
Published online on: 01 August 2004

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Article

Ubiquitous p63 expression in human esophageal squamous cell carcinoma

Tadashi Hara, Hiroshi Kijima, Soichiro Yamamoto, Takahiro Kenmochi, Yosifumi Kise, Hikaru Tanaka, Osamu Chino, Hideo Shimada, Kensuke Takazawa, Makiko Tanaka, Sadaki Inokuchi, Hiroyasu Makuuchi
Pages: 169-173
Published online on: 01 August 2004

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Article

The Na+/H+ exchange inhibitor HOE642 prevents stress-induced epithelial barrier dysfunction

Peter Nowak, Roman Blaheta, Alina Schuller, Jindrich Cinatl, Gerhard Wimmer-Greinecker, Anton Moritz, Martin Scholz
Pages: 175-178
Published online on: 01 August 2004

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Article

Expression of CD34-positive sinusoidal endothelial cells in patients with HBV-associated chronic liver diseases

Shigeru Ohmori, Katsuya Shiraki, Kazushi Sugimoto, Yutaka Yamanaka, Yumi Yamaguchi, Yukiko Saitou, Katsuhiko Fujikawa, Kazumoto Murata, Takeshi Nakano
Pages: 179-184
Published online on: 01 August 2004

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Article

The relationship of the human glutathione S-transferase P1 polymorphism and chemotherapeutic sensitivity in head and neck squamous carcinoma

Shinobu Kimura, Yukari Imagawa, Kenichi Satake, Mamoru Tsukuda
Pages: 185-189
Published online on: 01 August 2004

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Article

Reduced intestinal inflammation induced by dextran sodium sulfate in interleukin-6-deficient mice

Yuji Naito, Tomohisa Takagi, Kazuhiko Uchiyama, Masaaki Kuroda, Satoshi Kokura, Hiroshi Ichikawa, Rie Yanagisawa, Ken-Ichiro Inoue, Hirohisa Takano, Masahiko Satoh, Norimasa Yoshida, Takeshi Okanoue, Toshikazu Yoshikawa
Pages: 191-196
Published online on: 01 August 2004

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Article

Lysosomal dysfunction on hydrogen peroxide-induced apoptosis of osteoarthritic chondrocytes

Toshiaki Takahashi, Ken-Ichi Kitaoka, Yasuhiro Ogawa, Toshihiro Kobayashi, Harumichi Seguchi, Toshikazu Tani, Shoji Yoshida
Pages: 197-200
Published online on: 01 August 2004

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Article

Development of pancreatic islets in pancreatic polypeptide-overexpressing mice

Hideki Yuzuriha, Akio Inui, Akihiro Asakawa, Naohiko Ueno, Ruka Sakamaki, Naotaka Shinfuku, Masato Kasuga, Mineko Fujimiya
Pages: 201-205
Published online on: 01 August 2004

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Article

Induction of polycystic ovary by testosterone in immature female rats: Modulation of apoptosis and attenuation of glucose/insulin ratio

R. Beloosesky, R. Gold, B. Almog, R. Sasson, A. Dantes, A. Land-Bracha, L. Hirsh, J. Itskovitz-Eldor, J. B. Lessing, R. Homburg, A. Amsterdam
Pages: 207-215
Published online on: 01 August 2004

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Article

Identification of genes differentially expressed in breast cancer cell line SKBR3: Potential identification of new prognostic biomarkers

Marianne Leirdal, Mohsen Shadidy, Øystein Røsok, Mouldy Sioud
Pages: 217-222
Published online on: 01 August 2004

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Article

Cellular analysis of growth suppression induced by the Notch ligands, Delta-1 and Jagged-1 in two myeloid leukemia cell lines

Mai Murata-Ohsawa, Shuji Tohda, Nobuo Nara
Pages: 223-226
Published online on: 01 August 2004

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Article

Induction of apoptotic cell death by mycelium extracts of Phellinus linteus in human neuroblastoma cells

Yung Hyun Choi, Man Kyu Huh, Chung-Ho Ryu, Byung Tae Choi, Young-Kee Jeong
Pages: 227-232
Published online on: 01 August 2004

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Article

Substrate specificity of Xenopus matrix metalloproteinase stromelysin-3

Tosikazu Amano, Liezhen Fu, Shelley Sahu, Meghan Markey, Yun-Bo Shi
Pages: 233-239
Published online on: 01 August 2004

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Article

Role of caspase in CD80 expression of superantigen-stimulated monocytes

Fumiaki Shinohara, Keiko Sato, Maiko Suzuki, Haruhiko Takada, Seishi Echigo, Hidemi Rikiishi
Pages: 241-246
Published online on: 01 August 2004

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Article

Dynamics and regional distribution of c-fos protein expression in rat brain after a closed head injury

Andrea Czigner, András Mihály, Orsolya Farkas, András Büki, Beáta Krisztin-Péva, Endre Dobó, Pál Barzó
Pages: 247-252
Published online on: 01 August 2004

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Article

Induction of apoptosis by ar-turmerone on various cell lines

Mingjie Ji, Jaesue Choi, Jeongnyeo Lee, Yongkyu Lee
Pages: 253-256
Published online on: 01 August 2004

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Article

Development and characterization of five cell models for chemoresistance studies of human ovarian carcinoma

Li Li, Yingzi Luan, Gangduo Wang, Bujian Tang, Danrong Li, Wei Zhang, Xiping Li, Jinshun Zhao, Hong Ding, Eddie Reed, Qingdi Q. Li
Pages: 257-264
Published online on: 01 August 2004

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Article

Early graft hemodynamics in living related liver transplantation evaluated by Doppler ultrasonography

Shigeo Nakanishi, Katsuya Shiraki, Kouji Yamamoto, Yukiko Saitou, Shigeru Ohmori, Takeshi Nakano, Shugo Mizuno, Masami Tabata, Kentarou Yamagiwa, Hajime Yokoi, Shuji Isaji, Shinji Uemoto
Pages: 265-269
Published online on: 01 August 2004

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Article

Adenoviral-mediated transfer of p53 gene enhances TRAIL-induced apoptosis in human hepatocellular carcinoma cells

Hidekazu Inoue, Katsuya Shiraki, Kazumoto Murata, Kazushi Sugimoto, Tomoyuki Kawakita, Yumi Yamaguchi, Yukiko Saitou, Naoyuki Enokimura, Norihiko Yamamoto, Yutaka Yamanaka, Takeshi Nakano
Pages: 271-275
Published online on: 01 August 2004

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Article

Role of regucalcin in liver nuclear function: Binding of regucalcin to nuclear protein or DNA and modulation of tumor-related gene expression

Yoshinori Tsurusaki, Masayoshi Yamaguchi
Pages: 277-281
Published online on: 01 August 2004

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Article

Influence of DMBA-induced mammary cancer on the liver CPT I, mit HMG-CoA synthase and PPARα mRNA expression in rats fed a low or high corn oil diet

Raquel Moral, Montserrat Solanas, Eva Mónica Manzanares, Diego Haro, Eduard Escrich
Pages: 283-287
Published online on: 01 August 2004

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Article

CpG methylation of the ERα# and ERβ genes in breast cancer

Sun Jung Kim, Tae Won Kim, Su-Young Lee, Sang-Jae Park, Hee Sung Kim, Ki-Wook Chung, Eun Sook Lee, Han-Sung Kang
Pages: 289-293
Published online on: 01 August 2004

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Article

Production and efficacy of a dendritic cell-based therapeutic vaccine for murine chronic hepatitis B virus carrierer

S. M.F. Akbar, Shinya Furukawa, Aki Hasebe, Norio Horiike, Kojiro Michitaka, Morikazu Onji
Pages: 295-299
Published online on: 01 August 2004

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Article

Distribution of HBV genotypes and mutants among hepatitis B infected patients from northern Poland

Krzysztof Piotr Bielawski, Aleksandra Dybikowska, Urszula Lisowska-Charmuszko, Piotr Stalke, Katarzyna Gregorowicz, Hanna Trocha, Anna Podhajska
Pages: 301-304
Published online on: 01 August 2004

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Article

Differentiation of HL-60 myeloid leukemia cells induced by all-trans retinoic acid is enhanced in combination with caffeic acid

Renata Veselská, Karel Zitterbart, Jan Auer, Jakub Neradil
Pages: 305-310
Published online on: 01 August 2004

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Review

Hematological findings in SARS patients and possible mechanisms (Review)

Mo Yang, Chi Kong Li, Karen Li, K. L.E. Hon, M. H.L. Ng, Paul K.S. Chan, Tai Fai Fok
Pages: 311-315
Published online on: 01 August 2004

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Article

The pro- and anti-inflammatory markers in patients with acute myocardial infarction and chronic stable angina

Wojciech Wojakowski, Katarzyna Maslankiewicz, Andrzej Ochala, Rafal Wyderka, Izabela Zuk-Popiolek, Zbigniew Flak, Iwona Mroz, Michal Tendera
Pages: 317-322
Published online on: 01 August 2004

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Article

Per os administration of 5-fluorocytosine is effective in the regression of CD-expressing liver metastases in rats

Adolfo Gavelli, Patrick Baqué, Nicole Brossettej, André Bourgeon, Pascal Staccini, Bernard Rossi, Valérie Pierrefite-Carle
Pages: 323-325
Published online on: 01 August 2004

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Article

Identification and characterization of human FCHO2 and mouse Fcho2 genes in silico

Masuko Katoh, Masaru Katoh
Pages: 327-331
Published online on: 01 August 2004

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Article

Identification and characterization of ARHGAP24 and ARHGAP25 genes in silico

Masuko Katoh, Masaru Katoh
Pages: 333-338
Published online on: 01 August 2004

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Journal Cover
February-2026 Volume 57 Issue 2

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

miR‑205: A dual regulator of angiogenesis in health and disease (Review)

Maria Oltra, Miriam Martínez‑Santos, Maria Ybarra, Maria Pires, Chiara Ceresoni, Clara Gomis‑Coloma, Cristina Medina‑Trillo, Javier Sancho, Jorge Barcia
Article Number: 51
Published online on: 29 December 2025

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Astragaloside IV: A multipotent phytochemical for treating fibrotic diseases (Review)

Mingyu Wu, Ke Li, Jiabin Wu, Qiuyu Zhang, Xiaotong Ma, Wei Dai, Haoyang Gao, Xianyi Ding, Wenhong Wang, Weihua Xiao
Article Number: 50
Published online on: 24 December 2025

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Activating transcription factors: Orchestrators of macrophage biology in pathological settings (Review)

Yue-Chen Liu, Jia-Wei Zhao, Xiong-Tao Yue, Qi-Jie Chen, Shan-Jie Rong, Shi-Wei Liu, Fei Sun, Chun-Liang Yang, Cong-Yi Wang
Article Number: 49
Published online on: 24 December 2025

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Role of SIRT3 in digestive system diseases and therapeutic prospects (Review)

Jiajia Li, Qian Liu, Shun Yao, Xin Li, Li Zhang, Yongfeng Wang, Guorong Wen, Jiaxing An, Hai Jin, Biguang Tuo
Article Number: 48
Published online on: 22 December 2025

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Article Open Access

Recombinant ADAMTS‑1 promotes muscle regeneration accompanied by downregulation of Notch signaling

Jin-Hwa Kim, Sang-Hyup Lee, Sang-Yoon Kim, Jeong-Won Kim, Ji-Soo Jeong, Eun-Hye Chung, Su-Ha Lee, Chang-Yeop Kim, Bong-Keun Choi, Je-Won Ko, Tae-Won Kim
Article Number: 47
Published online on: 22 December 2025

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A comprehensive review on pain: Model, target, therapy, and prospect (Review)

Chenyu Chang, Xutao Wu, Kejia Liu, Lei Wang, Mozili Adu, Qingyuan Lin, Huilian Huang, Qinge Ma, Rongrui Wei, Xiaoyun Wang, Wenmin Liu
Article Number: 46
Published online on: 17 December 2025

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Retraction Open Access

[Retracted] Curculigoside attenuates myocardial ischemia‑reperfusion injury by inhibiting the opening of the mitochondrial permeability transition pore

Yanbing Zhao, Yuxuan Guo, Yuqiong Chen, Shuang Liu, Nan Wu, Dalin Jia
Article Number: 45
Published online on: 15 December 2025

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Nanomaterials and exercise interventions: A synergistic approach for atherosclerosis therapy (Review)

Quanquan Zhou, Ge‑Lin Zhang, Weitong Sun, Jiayi Cai, Li-Hua Yu
Article Number: 44
Published online on: 10 December 2025

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Article Open Access

Selective autophagic degradation of glycolytic activator PFKFB3 contributes to maintaining intestinal epithelial barrier in inflammatory bowel disease

Yiyang Pan, Feng Yang, Liucan Wang, Tianshu Yang, Guangsheng Du, Cong Xu, Hua Yang, Min Yu, Weidong Xiao
Article Number: 43
Published online on: 10 December 2025

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Lactylation‑mediated ferroptosis: A novel mechanism and therapeutic prospects in human diseases (Review)

Zhengjun Lin, Yugang Zou, Songzhu Zou, Kunming Wen
Article Number: 42
Published online on: 08 December 2025

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Dual role of lactate in ferroptosis: Mechanisms, pathophysiology and therapeutic opportunities (Review)

Qian Yu, Yu Kuang, Jie He, Li Yang, Xinjie Li, Hao Yu
Article Number: 41
Published online on: 08 December 2025

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Retraction Open Access

[Retracted] MicroRNA‑493‑5p promotes apoptosis and suppresses proliferation and invasion in liver cancer cells by targeting VAMP2

Guannan Wang, Xiaosan Fang, Meng Han, Xiaoming Wang, Qiang Huang
Article Number: 40
Published online on: 08 December 2025

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FGF4 alleviates the lung cell damage caused by high glucose via AMPK‑PGC‑1 signaling axis in vitro and in vivo

Qiujuan Fu, Yongfang Ou, Qin Wu, Jue Gong, Feixia Li, Tuxing Wang, Zhitai Lin, Kejie Huang, Jianlong Xie
Article Number: 39
Published online on: 05 December 2025

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STOML2 interacts with PHB to activate the MEK/ERK signaling pathway and mediates autophagy‑related proteins in the progression of hepatocellular carcinoma

Haoyang Hu, Haozhe Zhang, Shuai Han, Jianli Chen, Ying Xie
Article Number: 38
Published online on: 04 December 2025

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HMGB1 mediates low-dose ionizing radiation-induced Wnt/β-catenin activation in SRA01/04 cells: Mechanistic clues to early cataractogenesis

Ping Wang, Chunnan Piao, Dong Yan, Yingxue He, Yaru Li, Li Fan, Mei Tian
Article Number: 37
Published online on: 04 December 2025

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FBXO22 promotes hepatocellular carcinoma progression via paracrine myo‑inositol‑induced M2‑type polarization of macrophages

Liangliang Bai, Jing Xiong, Sihai Chen, Jiahao Hu, Meixia Zhang, Bimin Li, Jing Hu, Mingyan He
Article Number: 36
Published online on: 02 December 2025

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Branched‑chain amino acid metabolism and bone metabolism: Implications for osteoporosis pathogenesis and therapeutic strategies (Review)

Qi Xiao, Haimin Zeng, Ruhui Yang, Yuxin Zhan, Fangzhen Lin, Bofan Chen, Xiang Chen
Article Number: 35
Published online on: 02 December 2025

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Mitochondria-associated endoplasmic reticulum membranes: Emerging regulators of cardiac microvascular ischemia/reperfusion injury (Review)

Yan Wang, Baowei Feng, Yanting Wu, Zongle Sun, Hao Yuan, Wei Chen, Chang Zhao, Zhi Liu
Article Number: 34
Published online on: 02 December 2025

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Role of matrix metalloproteinases in the invasion of glioblastoma and drug interventions (Review)

Bohao Zheng, Ying Han, Haiying Zhang
Article Number: 33
Published online on: 01 December 2025

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Review

Bridging bench to bedside: Exosome‑based strategies for endometriosis diagnosis and treatment (Review)

Wanmeng Chen, Yujiu Ma, Xudong Zhang, Siwen Zhang, Shanshan Wu, Yimeng Lu, Jichun Tan
Article Number: 32
Published online on: 01 December 2025

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Retraction Open Access

[Retracted] miR‑381 functions as a tumor suppressor by targeting ETS1 in pancreatic cancer

Guanen Qiao, Jing Li, Jun Wang, Zhaoyang Wang, Wei Bian
Article Number: 31
Published online on: 01 December 2025

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Journal Cover
March-2026 Volume 57 Issue 3

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Harnessing MSC‑derived exosomes to modulate the pathophysiology of ASD: Recent advances and therapeutic implications (Review)

Zhaojian Sun, Nouman Amjad, Majid Muhammad, Zhiyuan Li
Article Number: 60
Published online on: 13 January 2026

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Retraction Open Access

[Retracted] Mechanism of cell death induced by silica nanoparticles in hepatocyte cells is by apoptosis

Ye Yang, Xinjing Du, Qiang Wang, Jianwei Liu, Enguo Zhang, Linlin Sai, Cheng Peng, Martin F. Lavin, Abrey Jie Yeo, Xu Yang, Hua Shao, Zhongjun Du
Article Number: 59
Published online on: 12 January 2026

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ZG16B: A key regulator of tumor progression and immune microenvironment modulation in cancer (Review)

Xing-Ming Chen, Yu-Bo Liang, Jin-Xiang Zuo, Zi-Sheng Yang, Le-Yu Zhang, Xin-Yu Zhang, Ping Wan, Yang Ke
Article Number: 58
Published online on: 09 January 2026

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