Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies

  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
International Journal of Molecular Medicine
Join Editorial Board Propose a Special Issue
Print ISSN: 1107-3756 Online ISSN: 1791-244X
presentation
International Journal of Molecular Medicine

Join Editorial Board Propose a Special Issue

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

  • Selected Issue
  • Current Issue
  • Forthcoming Issue
  • Special Issues
    • Open Special Issues
    • About Special Issues
  • Trending Articles
    • Most Read
    • Most Cited (Dimensions)
      • Past Two Years
      • Total
    • Most Cited (Crossref)
      • Past Year
      • Total
    • Social Media
      • Past Month
      • Past Year
      • Total
  • Information
    • Information for Authors
    • Contact
    • Editorial Policies
    • Editorial Academy
    • Aims and Scope
    • Abstracting and Indexing
    • Bibliographic Information
  • Archive
Journal Cover
April-2017 Volume 39 Issue 4

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journal Metrics

Impact Factor: 8.5

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review

Senescence of mesenchymal stem cells (Review)

Yi Li, Qiong Wu, Yujia Wang, Li Li, Hong Bu, Ji Bao
Pages: 775-782
Published online on: 09 March 2017

  • View Full Article Download
Article Open Access

Fisetin regulates astrocyte migration and proliferation in vitro

Nan Wang, Fang Yao, Ke Li, Lanlan Zhang, Guo Yin, Mingjun Du, Bingyi Wu
Pages: 783-790
Published online on: 15 February 2017

  • View Full Article Download
Article Open Access

MicroRNA-182 prevents vascular smooth muscle cell dedifferentiation via FGF9/PDGFRβ signaling

Nana Dong, Wei Wang, Jinwei Tian, Zulong Xie, Bo Lv, Jiannan Dai, Rui Jiang, Dan Huang, Shaohong Fang, Jiangtian Tian, Hulun Li, Bo Yu
Pages: 791-798
Published online on: 22 February 2017

  • View Full Article Download
Article Open Access

ROCK/actin/MRTF signaling promotes the fibrogenic phenotype of fibroblast-like synoviocytes derived from the temporomandibular joint

Seiji Yokota, Naoyuki Chosa, Seiko Kyakumoto, Hitomichi Kimura, Miho Ibi, Masaharu Kamo, Kazuro Satoh, Akira Ishisaki
Pages: 799-808
Published online on: 17 February 2017

  • View Full Article Download
Article Open Access

Prostate apoptosis response 4 (PAR4) expression modulates WNT signaling pathways in MCF7 breast cancer cells: A possible mechanism underlying PAR4-mediated docetaxel chemosensitivity

Simone Aparecida de Bessa Garcia, Ana Carolina Pavanelli, Natália Cruz e Melo, Maria Aparecida Nagai
Pages: 809-818
Published online on: 21 February 2017

  • View Full Article Download
Article Open Access

Protective effect of naringin against the LPS-induced apoptosis of PC12 cells: Implications for the treatment of neurodegenerative disorders

Hui Wang, You Song Xu, Miao Lin Wang, Chao Cheng, Rui Bian, Hao Yuan, Yi Wang, Ting Guo, Lin Lin Zhu, Hang Zhou
Pages: 819-830
Published online on: 22 February 2017

  • View Full Article Download
Article Open Access

Autophagy induction in the skeletal myogenic differentiation of human tonsil-derived mesenchymal stem cells

Saeyoung Park, Yoonyoung Choi, Namhee Jung, Jieun Kim, Seiyoon Oh, Yeonsil Yu, Jung-Hyuck Ahn, Inho Jo, Byung-Ok Choi, Sung-Chul Jung
Pages: 831-840
Published online on: 20 February 2017

  • View Full Article Download
Article Open Access

AJS1669, a novel small-molecule muscle glycogen synthase activator, improves glucose metabolism and reduces body fat mass in mice

Kazuhiro Nakano, Sen Takeshita, Noriko Kawasaki, Wataru Miyanaga, Yoriko Okamatsu, Mizuki Dohi, Tadakiyo Nakagawa
Pages: 841-850
Published online on: 07 March 2017

  • View Full Article Download
Article Open Access

Albumin-based nanoparticles as methylprednisolone carriers for targeted delivery towards the neonatal Fc receptor in glomerular podocytes

Lin Wu, Mingyu Chen, Huijuan Mao, Ningning Wang, Bo Zhang, Xiufen Zhao, Jun Qian, Changying Xing
Pages: 851-860
Published online on: 21 February 2017

  • View Full Article Download
Article Open Access

Overexpression of wild-type p21Ras plays a prominent role in colorectal cancer

Shuang Bai, Qiang Feng, Xin-Yan Pan, Hong Zou, Hao-Bin Chen, Peng Wang, Xin-Liang Zhou, Yan-Ling Hong, Shu-Ling Song, Ju-Lun Yang
Pages: 861-868
Published online on: 21 February 2017

  • View Full Article Download
Article Open Access

Minocycline attenuates sevoflurane-induced cell injury via activation of Nrf2

Yue Tian, Xiuying Wu, Shanbin Guo, Ling Ma, Wei Huang, Xiaochun Zhao
Pages: 869-878
Published online on: 28 February 2017

  • View Full Article Download
Article Open Access

Homemade-device-induced negative pressure promotes wound healing more efficiently than VSD-induced positive pressure by regulating inflammation, proliferation and remodeling

Jinyan Liu, Feng Hu, Jintian Tang, Shijie Tang, Kun Xia, Song Wu, Chaoqi Yin, Shaohua Wang, Quanyong He, Huiqing Xie, Jianda Zhou
Pages: 879-888
Published online on: 13 March 2017

  • View Full Article Download
Article Open Access

Consumption of policosanol enhances HDL functionality via CETP inhibition and reduces blood pressure and visceral fat in young and middle-aged subjects

Jae-Yong Kim, Seong-Min Kim, Suk-Jeong Kim, Eun-Young Lee, Jae-Ryong Kim, Kyung-Hyun Cho
Pages: 889-899
Published online on: 24 February 2017

  • View Full Article Download
Article Open Access

MicroRNA-7 functions as a tumor-suppressor gene by regulating ILF2 in pancreatic carcinoma Retraction in /10.3892/ijmm.2025.5542

Yiliang Bi, Wei Shen, Min Min, Yan Liu
Pages: 900-906
Published online on: 17 February 2017

  • View Full Article Download
Article Open Access

Tissue engineered vascularized periosteal flap enriched with MSC/EPCs for the treatment of large bone defects in rats

Christoph Nau, Dirk Henrich, Caroline Seebach, Katrin Schröder, John H. Barker, Ingo Marzi, Johannes Frank
Pages: 907-917
Published online on: 21 February 2017

  • View Full Article Download
Article Open Access

Comparison of the proliferation, migration and angiogenic properties of human amniotic epithelial and mesenchymal stem cells and their effects on endothelial cells

Qianqian Wu, Tao Fang, Hongxin Lang, Min Chen, Ping Shi, Xining Pang, Guoxian Qi
Pages: 918-926
Published online on: 20 February 2017

  • View Full Article Download
Article Open Access

Overexpression of TMPRSS4 promotes tumor proliferation and aggressiveness in breast cancer

Xiao-Mei Li, Wen-Lou Liu, Xu Chen, Ya-Wen Wang, Duan-Bo Shi, Hui Zhang, Ran-Ran Ma, Hai-Ting Liu, Xiang-Yu Guo, Feng Hou, Ming Li, Peng Gao
Pages: 927-935
Published online on: 17 February 2017

  • View Full Article Download
Article Open Access

Transplantation of betatrophin-expressing adipose-derived mesenchymal stem cells induces β-cell proliferation in diabetic mice

Liang-Liang Sun, Tian-Jin Liu, Limei Li, Wei Tang, Jun-Jie Zou, Xiang-Fang Chen, Jiao-Yang Zheng, Bei-Ge Jiang, Yong-Quan Shi
Pages: 936-948
Published online on: 10 March 2017

  • View Full Article Download
Article Open Access

Kindlin-1 contributes to EGF-induced re-epithelialization in skin wound healing

Congcong Shen, Linlin Sun, Ningwen Zhu, Fazhi Qi
Pages: 949-959
Published online on: 07 March 2017

  • View Full Article Download
Article Open Access

Fenofibrate exerts protective effects against gentamicin-induced toxicity in cochlear hair cells by activating antioxidant enzymes

Channy Park, Hye-Min Ji, Se-Jin Kim, Sung-Hee Kil, Joon No Lee, Seongae Kwak, Seong-Kyu Choe, Raekil Park
Pages: 960-968
Published online on: 10 March 2017

  • View Full Article Download
Article

A long-lasting dipeptidyl peptidase-4 inhibitor, teneligliptin, as a preventive drug for the development of hepatic steatosis in high-fructose diet-fed ob/ob mice

Ken Nakamura, Shinya Fukunishi, Keisuke Yokohama, Hideko Ohama, Yusuke Tsuchimoto, Akira Asai, Yasuhiro Tsuda, Kazuhide Higuchi
Pages: 969-983
Published online on: 20 February 2017

  • View Full Article Download
Article

Icaritin, a novel plant-derived osteoinductive agent, enhances the osteogenic differentiation of human bone marrow- and human adipose tissue-derived mesenchymal stem cells

Tao Wu, Tao Shu, Le Kang, Jinhui Wu, Jianzhou Xing, Zhiqin Lu, Shuxiang Chen, Jun Lv
Pages: 984-992
Published online on: 24 February 2017

  • View Full Article Download
Article

Tetrandrine prevents multidrug resistance in the osteosarcoma cell line, U-2OS, by preventing Pgp overexpression through the inhibition of NF-κB signaling

Yandong Lu, Fangguo Li, Tao Xu, Jie Sun
Pages: 993-1000
Published online on: 17 February 2017

  • View Full Article Download
Article

Heat shock protein 90/Akt pathway participates in the cardioprotective effect of exogenous hydrogen sulfide against high glucose-induced injury to H9c2 cells Corrigendum in /10.3892/ijmm.2018.3708

Xiao Ke, Jingfu Chen, Longyun Peng, Wei Zhang, Yiying Yang, Xinxue Liao, Liqiu Mo, Ruixian Guo, Jianqiang Feng, Chengheng Hu, Ruqiong Nie
Pages: 1001-1010
Published online on: 15 February 2017

  • View Full Article Download
Article

Possible protective role of the ABCA4 gene c.1268A>G missense variant in Stargardt disease and syndromic retinitis pigmentosa in a Sicilian family: Preliminary data

Rosalia D'Angelo, Luigi Donato, Isabella Venza, Concetta Scimone, Pasquale Aragona, Antonina Sidoti
Pages: 1011-1020
Published online on: 10 March 2017

  • View Full Article Download
Article

3'-Daidzein sulfonate sodium inhibits neuronal apoptosis induced by cerebral ischemia-reperfusion

Ruizhen Liu, Xinming Zhong, Jing Zeng, Zhihua Huang, Xiao Li, Hai Xiao, Qin Chen, Dongliang Li
Pages: 1021-1028
Published online on: 10 March 2017

  • View Full Article Download
Article

Glucagon-like peptide 1 receptor agonist ameliorates the insulin resistance function of islet β cells via the activation of PDX-1/JAK signaling transduction in C57/BL6 mice with high-fat diet-induced diabetes

Tao Hao, Hongtao Zhang, Sheyu Li, Haoming Tian
Pages: 1029-1036
Published online on: 07 March 2017

  • View Full Article Download
Article

ICT1 knockdown inhibits breast cancer cell growth via induction of cell cycle arrest and apoptosis

Chen Wang, Chenlu Liang, Weiliang Feng, Xianghou Xia, Feng Chen, Enqi Qiao, Xiping Zhang, Daobao Chen, Zhiqiang Ling, Hongjian Yang
Pages: 1037-1045
Published online on: 09 March 2017

  • View Full Article Download
Article

Regulation of Runx2 by microRNA-9 and microRNA-10 modulates the osteogenic differentiation of mesenchymal stem cells

Hong Luo, Hualin Gao, Fang Liu, Bing Qiu
Pages: 1046-1052
Published online on: 10 March 2017

  • View Full Article Download
Article

Incretins amplify TNF-α-stimulated IL-6 synthesis in osteoblasts: Suppression of the IκB/NF-κB pathway

Kazuhiko Fujita, Haruhiko Tokuda, Naohiro Yamamoto, Shingo Kainuma, Tetsu Kawabata, Go Sakai, Gen Kuroyanagi, Rie Matsushima‑Nishiwaki, Atsushi Harada, Osamu Kozawa, Takanobu Otsuka
Pages: 1053-1060
Published online on: 15 February 2017

  • View Full Article Download
Journal Cover
September-2026 Volume 58 Issue 3

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journal Metrics

Impact Factor: 8.5

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Mechanisms and therapeutic strategies of pyroptosis in sepsis‑induced acute lung injury (Review)

Wenyu Wu, Nuoran Li, Guoshu Deng, Suyi Yang, Ruifeng Zeng, Rui Chen, Jun Li
Article Number: 264
Published online on: 22 July 2026

  • View Full Article Download
Review Open Access

Gut‑bone metabolites: SCFAs, polyamines and microbial metabolomics in osteoporosis risk and therapy (Review)

Fuchao Chen, Jingyue Sun, Xiao Wang
Article Number: 263
Published online on: 21 July 2026

  • View Full Article Download
Expression of Concern Open Access

[Expression of Concern] Exposure to acoustic stimuli promotes the development and differentiation of neural stem cells from the cochlear nuclei through the clusterin pathway

Tao Xue, Li Wei, Ding-Jun Zha, Li Qiao, Lian-Jun Lu, Fu-Quan Chen, Jian-Hua Qiu
Article Number: 262
Published online on: 20 July 2026

  • View Full Article Download
Article Open Access

Cepharanthine inhibits tick‑borne encephalitis virus infection through modulation of the stress and inflammation response

Wan-Da Tang, Lan-Juan Zhao
Article Number: 261
Published online on: 16 July 2026

  • View Full Article Download
Article Open Access

circCACNA1D drives pulmonary fibrosis by regulating pyruvate kinase M2 dimer‑tetramer switching

Yujie Wang, Xiaoting Li, Meirong Wang, Nailiang Zhai, Mengqi Jiang, Bo Liu, Changjun Lv, Songzi Zhang, Xiaodong Song, Jinjin Zhang
Article Number: 260
Published online on: 15 July 2026

  • View Full Article Download
Review Open Access

Recent progress and therapeutic strategies in the treatment of cervical neuroendocrine neoplasms (Review)

Yanpeng Tian, Yu Zhang, Liling Wang, Zhongkang Li, Xiaotong Xu, Shouze Liu, Shenyu Yang, Xiangyang Ren, Menghan Xu, Xingzi Chang, Xianghua Huang, Qian Zhao, Ruixia Guo
Article Number: 259
Published online on: 15 July 2026

  • View Full Article Download
Review Open Access

Neurofibromin in bone disease: Mechanisms and therapeutic implications (Review)

Shuhong Zhang, Ge Yang
Article Number: 258
Published online on: 14 July 2026

  • View Full Article Download
Review Open Access

Exercise‑induced exosomal noncoding RNAs: Molecular signaling cascades in bone remodeling and translational applications in sports‑related bone injuries (Review)

Bin Tian, Xuesong Chen, Jiang Zheng, Xin Kang
Article Number: 257
Published online on: 14 July 2026

  • View Full Article Download
Review Open Access

Targeting alveolar type II cell dysfunction in idiopathic pulmonary fibrosis: Molecular mechanisms and emerging therapeutic strategies (Review)

Tianhao Xie, Kang Hu, Shu Pan, Xin Tong, Haitong Huang, Hao Ding, Jun Zhao
Article Number: 256
Published online on: 13 July 2026

  • View Full Article Download
Article Open Access

Tubular PFKFB3 drives diabetic kidney fibrosis via lactate‑dependent H4K12 lactylation and HIPK2 transactivation

Mingkun Xu, Linhang Fu, Yulong Zhang, Xiuli Guo, Han Wu, Sijing Gao, Fei Xiao, Li Xu
Article Number: 255
Published online on: 13 July 2026

  • View Full Article Download
Retraction Open Access

[Retracted] p73 participates in WWOX-mediated apoptosis in leukemia cells

Donghong Lin, Zhaolei Cui, Lingying Kong, Feng Cheng, Jianping Xu, Fenghua Lan
Article Number: 254
Published online on: 13 July 2026

  • View Full Article Download
Article Open Access

Role of hyperthermia in overcoming HPV‑mediated MHC‑Ⅰ downregulation and promoting immune surveillance

Hanyu Wang, Hongxin Lang, Yaoxing Guo, Te Sun, Yuansong Bai, Tao Zhang, Rui-Qun Qi
Article Number: 253
Published online on: 10 July 2026

  • View Full Article Download
Review Open Access

Endocrine‑metabolic imbalance drives osteoarthritis: From whole‑joint pathobiology to precision therapy (Review)

Ruhui Yang, Haimin Zeng, Qi Xiao, Yining Xie, Yi Long, Xiang Chen
Article Number: 252
Published online on: 09 July 2026

  • View Full Article Download
Expression of Concern Open Access

[Expression of Concern] Roles and mechanisms of action of HNF‑4α in the hepatic differentiation of WB‑F344 cells

Yumeng Shi, Dehua Zhou, Bingyi Wang, Deren Zhou, Baomin Shi
Article Number: 251
Published online on: 08 July 2026

  • View Full Article Download
Article Open Access

Phenylalanine exacerbates psoriasiform inflammation through NF‑κB‑mediated dendritic cell activation and Th17 polarization

Yaohan Xu, Jing Pan, Jie Chen, Yutao Zhu, Miaolian Cai, Zeyu Ma, Siji Chen, Tianze Yu, Yushu Wei, Jingying Pan, Kunliang Luo, Yinjing Song, Stijn Van Der Veen, Hao Cheng
Article Number: 250
Published online on: 08 July 2026

  • View Full Article Download
Review Open Access

Protective effects of Astragaloside IV on various liver diseases: From chemistry to herbal medicines (Review)

Jialu Shi, Xiaoyu Zhou, Jiabin Wu, Liru Zeng, Xia Wang, Wei Li, Xiao Huang, Xiaoyu Deng, Wenhong Wang
Article Number: 249
Published online on: 07 July 2026

  • View Full Article Download
Review Open Access

GRP78 dysregulation: A proposed molecular mechanism linking the tumor microenvironment to sepsis susceptibility in patients with cancer (Review)

Hang Ruan, Meipeng Zhu, Shi-Yan Liu, Li-Juan Zou, Shu-Sheng Li
Article Number: 248
Published online on: 07 July 2026

  • View Full Article Download
Review Open Access

FGFR1 signaling in rheumatoid arthritis: Mechanisms of bone destruction and therapeutic targeting (Review)

Changzhong Qian, Zhenyu Zhang, Xian Wu, Huibo Ti, Junjie Wu, Zhengdong Yuan, Xia Li, Feng-Lai Yuan
Article Number: 247
Published online on: 06 July 2026

  • View Full Article Download
Retraction Open Access

[Retracted] β‑catenin signaling induces the osteoblastogenic differentiation of human pre‑osteoblastic and bone marrow stromal cells mainly through the upregulation of osterix expression

Bo Liu, Song Wu, Lihua Han, Chaoyue Zhang
Article Number: 246
Published online on: 06 July 2026

  • View Full Article Download
Article Open Access

Single‑cell atlas reveals a Wilms' tumor 1‑mediated axis driving granulosa cell senescence in human ovarian aging

Yanfang Du, Congyu Zhou, Yanpeng Tian, Zhongkang Li, Xianghua Huang
Article Number: 245
Published online on: 03 July 2026

  • View Full Article Download
Review Open Access

TRPV1‑mediated central sensitisation: Core mechanisms of migraine chronification and novel targeted therapeutic strategies (Review)

Mingxia Zhang, Yuting Pu, Yujie Zhang, Jia Hu, Shuangyang Li, Hongmei Tang, Bangjiang Fang, Xue Bai
Article Number: 244
Published online on: 02 July 2026

  • View Full Article Download
Correction Open Access

[Corrigendum] Arginine ADP‑ribosyltransferase 1 promotes angiogenesis in colorectal cancer via the PI3K/Akt pathway

Lian Yang, Ming Xiao, Xian Li, Yi Tang, Ya-Lan Wang
Article Number: 243
Published online on: 02 July 2026

  • View Full Article Download
Review Open Access

Research progress on the chemical and pharmacological effects of Semen Strychni (Review)

Jingxin Mao, Xin Du, Dan Zeng, Xin Luo, Yan Li
Article Number: 242
Published online on: 02 July 2026

  • View Full Article Download
Article Open Access

FLI1 enhances the malignant phenotype of glioma cells and exerts immunomodulatory effects through feedback crosstalk with exonic circRNA FECR1 and interferon‑induced ISG15

Xue Wen, Xiaoyi Gu, Xu Yan, Naifei Chen, Lei Zhou, Hui Li, Andrew R. Hoffman, Wei Li, Ji-Fan Hu, Jiuwei Cui
Article Number: 241
Published online on: 01 July 2026

  • View Full Article Download
Review Open Access

Role of ZEB1 in angiogenesis and therapeutic potential (Review)

Ruoxin Ren, Chunxiao Yan, Yao Xiang, Lin Jin, Fang Cheng, Lijun Zhang
Article Number: 240
Published online on: 01 July 2026

  • View Full Article Download
Review Open Access

Endothelial dysfunction: A central mechanism linking autosomal dominant polycystic kidney disease and intracranial aneurysms (Review)

Xiaohong Xu, Ruyi Xu, Liexiang Zhang
Article Number: 239
Published online on: 01 July 2026

  • View Full Article Download
Correction Open Access

[Corrigendum] Effect of SDF‑1/CXCR4 axis on the migration of transplanted bone mesenchymal stem cells mobilized by erythropoietin toward lesion sites following spinal cord injury

Jun Li, Weichun Guo, Min Xiong, Heng Han, Jie Chen, Dan Mao, Bing Tang, Hualong Yu, Yun Zeng
Article Number: 238
Published online on: 01 July 2026

  • View Full Article Download
Review Open Access

Exercise and fluoxetine in Alzheimer's disease: Molecular mechanisms of synergistic and antagonistic effects (Review)

Mei Wu, Yan Li
Article Number: 237
Published online on: 30 June 2026

  • View Full Article Download
Review Open Access

Oral‑gut axis in systemic disease: A barrier‑metabolism‑immunity three‑dimensional regulatory model (Review)

Qing Li, Mingrong Cheng, Weiwei Li, Xiaoyue Wang, Xiaoqing Liu, Yujie Yan
Article Number: 236
Published online on: 30 June 2026

  • View Full Article Download
Review Open Access

ABCG2 transporter: Structural and functional associations with gout (Review)

Muhammad Arslan Asif, Zeshan Zulfiqar, Bahar E. Mustafa, Usman Nazir, Jiamen Sun, Zhichang Wang, Yalei Cui, Sun Hao, Liu Boshuai, Yinghua Shi
Article Number: 235
Published online on: 30 June 2026

  • View Full Article Download
Review Open Access

Neuropilin‑1: Emerging roles in nerve‑vessel‑bone coupling during fracture repair (Review)

Keyue Zhang, Tong Li, Huan Liu, Huibo Ti, Zhenyu Zhang, Zhengdong Yuan, Junjie Wu, Xielin Yan, Zixin Luo, Haiting Hu, Xingchen Yao, Shuwen Shi, Xian Wu, Feng-Lai Yuan, Xiao Chen
Article Number: 234
Published online on: 30 June 2026

  • View Full Article Download
Correction Open Access

[Corrigendum] Crocin exerts anti‑inflammatory and anti‑catabolic effects on rat intervertebral discs by suppressing the activation of JNK

Kang Li, Yan Li, Zhenjiang Ma, Jie Zhao
Article Number: 233
Published online on: 29 June 2026

  • View Full Article Download
Review Open Access

Skeletal muscle‑derived extracellular vesicles in multi‑organ degenerative disease: Mechanisms and therapeutic delivery perspectives (Review)

Xianji Wei, Chengyan Guo, Wei Zhang, Guanyi Wang, Wenjing Li, Binghong Gao, Bo Gao, Lingli Zhang
Article Number: 232
Published online on: 26 June 2026

  • View Full Article Download
Journal Cover
October-2026 Volume 58 Issue 4

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journal Metrics

Impact Factor: 8.5

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Retraction Open Access

[Retracted] Resistant starch prevents tumorigenesis of dimethylhydrazine‑induced colon tumors via regulation of an ER stress‑mediated mitochondrial apoptosis pathway  

Qiuyu Wang, Peng Wang, Zhigang Xiao
Article Number: 281
Published online on: 10 August 2026

  • Download
Review Open Access

XBP1 signaling from tumor metabolic stress to myeloid driven immunotherapy resistance (Review)

Ziwei Chen, Jiaqi Wu, Wenxi Liu, Jie Tan, Xiaochun Peng, Yanhua Zhang, Gai Liang
Article Number: 280
Published online on: 05 August 2026

  • Download
Review Open Access

Decoding miRNA‑146a: Mechanisms of action in cardiovascular diseases and endocrine metabolic disorders (Review)

Xiu Yang, Pengcheng Li, Hao Zhao
Article Number: 279
Published online on: 05 August 2026

  • Download
Review Open Access

Contribution of p38 MAPK in liver fibrosis: An overview of mechanisms, signaling pathways, and therapeutic targets (Review)

Xueqin Yang, Huarong Li, Hao Ye, Ting Wu, Fangyun Xu, Chao Hu, Chunlei Yu, Pian Ye
Article Number: 278
Published online on: 05 August 2026

  • View Full Article Download
Correction Open Access

[Corrigendum] Peroxisome proliferator‑activated receptor α regulates acesulfame‑K‑induced NAFLD via hepatic PLCβ: Foe and friend

Peng-Yao Lin, Jia-Rong Xie, Tian-Chen Qian, Shi-Song Wang, Si-Yi Yu, Wen-Bo Shi, Ying Wang, Lu-Ze Cen, Qing-Jing Zhu, Yi-Yang Zheng, Hui Gao, Rong Fang, Zhao-Xia Xia, Ai-Ming Liu, Lei Xu
Article Number: 277
Published online on: 05 August 2026

  • View Full Article Download
Review Open Access

Multi‑omics insights into uveitis: From mechanisms to precision medicine (Review)

Chengzhi Liu, Qiong Wu, Mingzhen Yuan, Mingyue Liu, Xinyu Wang, Jiaqi Shen, Xusheng Cao
Article Number: 276
Published online on: 03 August 2026

  • View Full Article Download
Retraction Open Access

[Retracted] Effects of miRNA‑455 on cardiac hypertrophy induced by pressure overload

Chuntao Wu, Shimin Dong, Yongjun Li
Article Number: 275
Published online on: 03 August 2026

  • View Full Article Download
Article Open Access

Energy stress activates AMPK to suppress ferroptosis in neurodegenerative proteinopathies

Yuanyuan Yong, Yuxin Hu, Qian Feng, Xiaogang Zhou, Lu Yu, Dalian Qin, Jianing Mi, Jianming Wu, Jianxin Liu, Anguo Wu
Article Number: 274
Published online on: 31 July 2026

  • View Full Article Download
Article Open Access

Brazilin attenuates methylglyoxal‑induced endothelial injury by enhancing eIF5A hypusination and inhibiting the AMPK/mTOR‑mediated autophagy/apoptosis axis in vitro and in vivo

Yu Liang, Jinxiang Chen, Haiyang Li, Junjing Xiong, Jingcan You, Liqun Wang, Jianbo Wu, Youkun Zheng, Mao Luo
Article Number: 273
Published online on: 30 July 2026

  • View Full Article Download
Review Open Access

Post‑translational modifications in atherosclerosis: Roles, mechanisms and therapeutic potential (Review)

Xiaoxiang Xu, Fei Ma, Wei Yu
Article Number: 272
Published online on: 30 July 2026

  • View Full Article Download
Review Open Access

Role of extracellular matrix in liver fibrosis regression and regeneration (Review)

Yuanzhi Zhou, Zeyuan Qiang, Yang Duan, Jiwei Huang, Haichuan Wang
Article Number: 271
Published online on: 29 July 2026

  • View Full Article Download
Correction Open Access

[Corrigendum] Circulating microRNA profiles and the identification of miR‑593 and miR‑511 which directly target the PROP1 gene in children with combined pituitary hormone deficiency

Yanyan Hu, Qian Wang, Zengmin Wang, Fengxue Wang, Xiaobo Guo, Guimei Li
Article Number: 270
Published online on: 29 July 2026

  • View Full Article Download
Review Open Access

Unveiling the role of spatial transcriptomics in the analysis of the tumor immune microenvironment (Review)

Jialin Jiang, Xinyu Tu, Yi Cao, Qun Yan, Buqing Sai, Jian Ma
Article Number: 269
Published online on: 28 July 2026

  • View Full Article Download
Expression of Concern Open Access

[Expression of Concern] Luteolin protects mice from severe acute pancreatitis by exerting HO‑1‑mediated anti‑inflammatory and antioxidant effects

Jie Xiong, Kezhou Wang, Chunxiao Yuan, Rong Xing, Jianbo Ni, Guoyong Hu, Fengling Chen, Xingpeng Wang
Article Number: 268
Published online on: 27 July 2026

  • View Full Article Download
Article Open Access

circRNA_013145‑miR‑185‑5p‑RhoA axis: A novel mechanism in the pathophysiology of diabetes‑induced erectile dysfunction

Wenhan Huang, Xin Lv, Jiahua Qian, Yihao Chen, Yuhe Si, Jingwei Wang, Jianxiong Ma
Article Number: 267
Published online on: 24 July 2026

  • View Full Article Download
Review Open Access

Gut‑liver‑kidney axis: A systems biology framework for understanding and treating chronic kidney disease (Review)

Jinyi Hou, Yaotan Li, Shijia Lin, Qingqing Liu, Huijuan Zheng, Weijing Liu, Yaoxian Wang, Liang Peng, Zhen Wang
Article Number: 266
Published online on: 23 July 2026

  • View Full Article Download
Review Open Access

Effects of cuproptosis and its application in inflammatory bowel disease (Review)

Li Chen, Francis Atim Akanyibah, Jing Guan, Bing Pei, Bo Wang, Fei Mao
Article Number: 265
Published online on: 23 July 2026

  • View Full Article Download
Select a topic from the Information tab...
Special issues coming soon...
No data
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team