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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
March-2022 Volume 25 Issue 3

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Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

Pulsatilla decoction alleviates colitis by enhancing autophagy and regulating PI3K‑Akt‑mTORC1 signaling pathway

Xuewei Wang, Lijun Xu, Tao Wang, Jian Xu, Fugang Fan, Yu Zhang, Jinpin Wang, Qin Cao
Article Number: 108
Published online on: 31 January 2022

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Overexpression of Foxc1 ameliorates sepsis‑associated encephalopathy by inhibiting microglial migration and neuroinflammation through the IκBα/NF‑κB pathway

Hongyu Wang, Hongwei Wang, Yinsen Song, Congyan Liu, Xinling Qian, Dalong Zhang, Xin Jiang, Sisen Zhang
Article Number: 107
Published online on: 31 January 2022

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Article

Two PARP13 isoforms are associated with induction of antiviral factors in oral mucosal cells

Hiroki Kato, Kouji Ohta, Miyuki Sakuma, Shohei Fukada, Takako Naruse, Hideo Shigeishi, Hiromi Nishi, Masaaki Takechi
Article Number: 106
Published online on: 31 January 2022

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Correction Open Access

[Corrigendum] Transforming growth factor‑β1 induces fibrosis in rat meningeal mesothelial cells via the p38 signaling pathway

Xue-Jing Yue, Yan Guo, Hai-Jie Yang, Zhi-Wei Feng, Tong Li, Yu-Ming Xu
Article Number: 105
Published online on: 27 January 2022

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Long noncoding RNA LINC00649 functions as a microRNA‑432‑5p sponge to facilitate tumourigenesis in colorectal cancer by upregulating HDGF

Junjie Bao, Xiaokai Bi, Jingbo Wang, Xiaoqiang Li
Article Number: 104
Published online on: 26 January 2022

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Dihydromyricetin ameliorates oxygen‑glucose deprivation and re‑oxygenation‑induced injury in HT22 cells by activating the Wnt/β‑catenin signaling pathway

Xiaoxiao Tao, Yaping Jiang, Xian Zheng, Xiaoxiao Ji, Feifei Peng
Article Number: 103
Published online on: 26 January 2022

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GATA6‑induced FN1 activation promotes the proliferation, invasion and migration of oral squamous cell carcinoma cells

Jianbo Zhai, Gang Luo
Article Number: 102
Published online on: 26 January 2022

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Knockdown of ATG4A inhibits breast cancer progression and promotes tamoxifen chemosensitivity by suppressing autophagy

Qingfang Li, Lingling Zan
Article Number: 101
Published online on: 25 January 2022

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Pinus thunbergii bark extract rich in flavonoids promotes hair growth in dorsal skin by regulating inflammatory cytokines and increasing growth factors in mice

Young Her, Tae-Kyeong Lee, Hyejin Sim, Jae-Chul Lee, Dae Won Kim, Soo Young Choi, Jun Kee Hong, Ji-Won Lee, Jong-Dai Kim, Moo-Ho Won, Sung-Su Kim
Article Number: 100
Published online on: 25 January 2022

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Review Open Access

Cartilage tissue engineering: From proinflammatory and anti‑inflammatory cytokines to osteoarthritis treatments (Review)

Shuyu Liu, Zhenhan Deng, Kang Chen, Shengsheng Jian, Feifei Zhou, Yuan Yang, Zicai Fu, Huanyu Xie, Jianyi Xiong, Weimin Zhu
Article Number: 99
Published online on: 24 January 2022

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Atractylenolide III inhibits epithelial‑mesenchymal transition in small intestine epithelial cells by activating the AMPK signaling pathway

Mingjin Huang, Wenwen Jiang, Chunli Luo, Min Yang, Yan Ren
Article Number: 98
Published online on: 24 January 2022

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Retraction Open Access

[Retracted] MicroRNA‑145 inhibits the malignant phenotypes of gastric carcinoma cells via downregulation of fascin 1 expression

Minghui Xue, Lunde Zhao, Fang Yang, Zhenjuan Li, Guangyan Li
Article Number: 97
Published online on: 20 January 2022

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Protective effect of H2S on LPS‑induced AKI by promoting autophagy

Ting Li, Jie Zhao, Shuying Miao, Yiyang Chen, Yunfei Xu, Ying Liu
Article Number: 96
Published online on: 20 January 2022

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Article

FRAT1 promotes the angiogenic properties of human glioblastoma cells via VEGFA

Biao Yang, Dong Liu, Ye-Qing Ren, Yan-Qi Sun, Jian-Ping Zhang, Xiao-Gang Wang, Yong-Qiang Wu, Shu-Le Wang, Shi-Hao Guo, Geng Guo
Article Number: 95
Published online on: 20 January 2022

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Ginsenoside Rg3 protects glucocorticoid‑induced muscle atrophy in vitro through improving mitochondrial biogenesis and myotube growth

Ryuni Kim, Jee Won Kim, Sang-Jin Lee, Gyu-Un Bae
Article Number: 94
Published online on: 20 January 2022

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CpG site hypomethylation at ETS1‑binding region regulates DLK1 expression in Chinese patients with Tetralogy of Fallot

Guixiang Tian, Lili He, Ruoyi Gu, Jingwei Sun, Weicheng Chen, Yanyan Qian, Xiaojing Ma, Weili Yan, Zhenshan Zhao, Ziqing Xu, Meijiao Suo, Wei Sheng, Guoying Huang
Article Number: 93
Published online on: 20 January 2022

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Nicotine promotes chronic obstructive pulmonary disease via inducing pyroptosis activation in bronchial epithelial cells

Rubing Mo, Jun Zhang, Yongxing Chen, Yipeng Ding
Article Number: 92
Published online on: 18 January 2022

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Comparison of the effect of rotenone and 1‑methyl‑4‑phenyl‑1,2,3,6‑tetrahydropyridine on inducing chronic Parkinson's disease in mouse models

Jing Zhang, Bohao Sun, Jifeng Yang, Zhuo Chen, Zhengzheng Li, Nan Zhang, Hongzhi Li, Luxi Shen
Article Number: 91
Published online on: 17 January 2022

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Hyperbaric oxygen treatment improves pancreatic β‑cell function and hepatic gluconeogenesis in STZ‑induced type‑2 diabetes mellitus model mice

Caishun Zhang, Di Zhang, Haidan Wang, Qian Lin, Manwen Li, Junhua Yuan, Guangkai Gao, Jing Dong
Article Number: 90
Published online on: 17 January 2022

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Proteomic analysis of inhibitor of apoptosis protein‑like protein‑2 on breast cancer cell proliferation

Siqi Xiang, Lin Zhu, Zhiliang Zhang, Siyuan Wang, Ruxia Cui, Mingjun Xiang
Article Number: 89
Published online on: 17 January 2022

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A cerebrospinal fluid microRNA analysis: Progressive supranuclear palsy

Wakako Nonaka, Tadayuki Takata, Hisakazu Iwama, Satoshi Komatsubara, Hideki Kobara, Masaki Kamada, Kazushi Deguchi, Tetsuo Touge, Osamu Miyamoto, Takehiro Nakamura, Toshifumi Itano, Tsutomu Masaki
Article Number: 88
Published online on: 14 January 2022

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Epigallocatechin gallate enhances human lens epithelial cell survival after UVB irradiation via the mitochondrial signaling pathway

Qiuxin Wu, Jike Song, Yan'e Gao, Yingying Zou, Junguo Guo, Xiuyan Zhang, Dongmei Liu, Dadong Guo, Hongsheng Bi
Article Number: 87
Published online on: 14 January 2022

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Long non‑coding RNA CTBP1‑AS2 upregulates USP22 to promote pancreatic carcinoma progression by sponging miR‑141‑3p

Mingliang Zhang, Songbo Ma, Xuzhao Li, Henghai Yu, Yizheng Tan, Jun He, Xiaoping Wei, Junming Ma
Article Number: 86
Published online on: 14 January 2022

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RGMa regulates CCL5 expression via the BMP receptor in experimental autoimmune encephalomyelitis mice and endothelial cells

Shi Tang, Bao Su, Tao Tao, Weiping Yan, Rongrong Zhang, Xinyue Qin, Jinzhou Feng
Article Number: 85
Published online on: 13 January 2022

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NOX4 stimulates ANF secretion via activation of the Sirt1/Nrf2/ATF3/4 axis in hypoxic beating rat atria

Zhi-Yu Li, Ying Liu, Yue-Ying Wang, Xiang Li, Zhuo-Na Han, Lan Hong, Ying-Shun Li, Xun Cui
Article Number: 84
Published online on: 13 January 2022

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Total glucosides of paeony ameliorates oxidative stress, apoptosis and inflammatory response by regulating the Smad7‑TGF‑β pathway in allergic rhinitis

Yangzi Jin, Aichun Zhang
Article Number: 83
Published online on: 13 January 2022

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Article

Cellular response of lung fibroblasts and epithelial cells to particulate matter10 treatment examined via comparative transcriptome analysis

Kunhyang Park, Kwangho Kim, Tae Young Ryu, Jinkwon Lee, Moo-Seung Lee, Mi-Young Son, Seon-Jin Lee, Young-Jun Park, Hyun-Soo Cho, Dae-Soo Kim
Article Number: 82
Published online on: 13 January 2022

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Retraction Open Access

[Retracted] MicroRNA‑155 enhances the activation of Wnt/β‑catenin signaling in colorectal carcinoma by suppressing HMG‑box transcription factor 1

Ying-Chun Wan, Tao Li, Yang-Dong Han, Hai-Yan Zhang, Hai Lin, Bin Zhang
Article Number: 81
Published online on: 12 January 2022

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Synergetic protective effect of remote ischemic preconditioning and prolyl 4‑hydroxylase inhibition in ischemic cardiac injury

Juesheng Yang, Jiajun Xu, Lei Tao, Shiyong Wang, Haiyan Xiang, Yanhua Tang
Article Number: 80
Published online on: 11 January 2022

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B7‑H3 promotes the epithelial‑mesenchymal transition of NSCLC by targeting SIRT1 through the PI3K/AKT pathway

Haixiu Liao, Meng Ding, Nannan Zhou, Ying Yang, Liwen Chen
Article Number: 79
Published online on: 11 January 2022

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C‑X‑C receptor 7 agonist acts as a C‑X‑C motif chemokine ligand 12 inhibitor to ameliorate osteoclastogenesis and bone resorption

Alexander Patera Nugraha, Hideki Kitaura, Fumitoshi Ohori, Adya Pramusita, Saika Ogawa, Takahiro Noguchi, Aseel Marahleh, Yasuhiko Nara, Ria Kinjo, Itaru Mizoguchi
Article Number: 78
Published online on: 11 January 2022

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Survival‑related DLEU1 is associated with HPV infection status and serves as a biomarker in HPV‑infected cervical cancer

Aiping Dong, Bin Xu, Zhanzhao Wang, Xia Miao
Article Number: 77
Published online on: 10 January 2022

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Role of TGM2 in T‑cell lymphoblastic lymphoma via regulation of IL‑6/JAK/STAT3 signalling

Yuyan Wang, Ni Zheng, Tingting Sun, Hui Zhao, Ying Chen, Congcong Liu
Article Number: 76
Published online on: 10 January 2022

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Article

Long non‑coding RNA PCAT1 sponges miR‑134‑3p to regulate PITX2 expression in breast cancer

Weiming Tang, Guang Lu, Yin Ji, Yan Xu
Article Number: 75
Published online on: 10 January 2022

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Dexmedetomidine alleviates airway hyperresponsiveness and allergic airway inflammation through the TLR4/NF‑κB signaling pathway in mice

Shilin Xiao, Qianyu Wang, Huibin Gao, Xumin Zhao, Juan Zhi, Dong Yang
Article Number: 74
Published online on: 10 January 2022

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Journal Cover
September-2026 Volume 34 Issue 3

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Journal Metrics

Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review

Chronic kidney disease‑associated encephalopathy: Clinical features, pathomechanisms and emerging therapeutic strategies (Review)

Nanling Zeng, Ling Jiang, Yang Zhang, Jian Liu, Qiong Zhang, Lishang Liao, Qiongdan Hu
Article Number: 259
Published online on: 21 July 2026

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Retraction Open Access

[Retracted] Emodin promotes the arrest of human lymphoma Raji cell proliferation through the UHRF1‑DNMT3A‑∆Np73 pathways

Yun Lin, Weiming Chen, Zhihong Wang, Pengwei Cai
Article Number: 258
Published online on: 20 July 2026

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Article Open Access

Sedanolide alleviates LPS‑induced depressive‑like behaviors by modulating the C3a/C3aR signaling axis and microglial glycolysis

Shaocong Lu, Fangla Luo, Niqi Chen, Gongde Shi, Yeru Chen
Article Number: 257
Published online on: 16 July 2026

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Expression of Concern Open Access

[Expression of Concern] Chrysophanol inhibits proliferation and induces apoptosis through NF‑κB/cyclin D1 and NF‑κB/Bcl‑2 signaling cascade in breast cancer cell lines

Li Ren, Zhouping Li, Chunmei Dai, Danyu Zhao, Yanjie Wang, Chunyu Ma, Chun Liu
Article Number: 256
Published online on: 15 July 2026

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Article Open Access

PCSK9 alleviates doxorubicin‑induced pyroptosis of cardiomyocytes

Chaochu Cui, Jinyu Zhao, Xiaoqian Li, Shengming Huang, Gang Liu, Xinhui Xu, Can Guo, Tiesuo Zhao, Jiang Du, Shipeng Li, Xianwei Wang, Jianbo Yang
Article Number: 255
Published online on: 14 July 2026

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Review Open Access

From cell to disease: Regulatory networks and mechanisms of super‑enhancers in aging (Review)

Xiaodan Wang, Weiqian Deng, Shuangxi Tu, Haojun Tang, Kai Yin, Xiao Zhu
Article Number: 254
Published online on: 14 July 2026

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Retraction Open Access

[Retracted] Matrine‑induced apoptosis in Hep3B cells via the inhibition of MDM2

Ning Zhou, Jiequn Li, Ting Li, Guangshun Chen, Zhongqiang Zhang, Zhongzhou Si
Article Number: 253
Published online on: 13 July 2026

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Review Open Access

Role of PANoptosis in the development of gastric immunity and related gastric mucosal disease (Review)

Lan Wang, Zhiyuan Ma, Bei Ji, Shuhui Liu, Shuji Terai, Biguang Tuo, Taolang Li, Xuemei Liu
Article Number: 252
Published online on: 09 July 2026

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Article

Leonurine inhibits the proliferation and metastasis of liver cancer cells by regulating the PI3K/AKT signaling pathway via epithelial‑mesenchymal transition

Bowen Hu, Maher Al Hussan, Jiakai Zhang, Peihao Wen, Changjun Huang, Yang Chen, Huanfei Ding
Article Number: 251
Published online on: 08 July 2026

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Correction Open Access

[Corrigendum] Resistin aggravates the expression of proinflammatory cytokines in cerulein‑stimulated AR42J pancreatic acinar cells

Chong-Yi Jiang, Wei Wang
Article Number: 250
Published online on: 08 July 2026

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Review Open Access

A‑Raf: A serine/threonine protein kinase with important biological functions (Review)

Muhan Yang, Mengying Chen, Jinmei Wei, Yanling Li, Chen Long, Yan Lei, Yanhong Zhou
Article Number: 249
Published online on: 07 July 2026

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Review Open Access

Gut dysbiosis‑derived butyrate loss predicts feeding intolerance: Multiomics evidence guiding nurse‑driven microbiota‑supportive interventions (Review)

Ling Wei, Xiaohua Kong, Yuying Li, Huixia Wu, Yirong Gan, Fang Sun
Article Number: 248
Published online on: 07 July 2026

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Retraction Open Access

[Retracted] Network pharmacology combined with experimental validation to investigate the effect of Rongjin Niantong Fang on chondrocyte apoptosis in knee osteoarthritis

Jun Chen, Ting Zhang, Qingqing Luo, Ruyi Wang, Yuting Dai, Zhenyuan Chen, Chutian Zhang, Xuzheng Chen, Guangwen Wu
Article Number: 247
Published online on: 06 July 2026

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Article Open Access

Laggera alata attenuates LPS‑induced systemic inflammation and hepatic‑pulmonary injury by regulating PINK1/Parkin-associated mitophagy and macrophage polarization

Jiangcun Wei, Wen Zhong, Guangyun Zhou, Mingtao Huang, Xiaodong Huang, Jing Liang
Article Number: 246
Published online on: 02 July 2026

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Review Open Access

Proteolysis‑targeting chimeras in oral squamous cell carcinoma: Current evidence, translational challenges and future directions (Review)

Yun Bai, Danhua Ma, Xi Yang, Min Wang
Article Number: 245
Published online on: 02 July 2026

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Review Open Access

Evolving role of biomarkers beyond prostate‑specific antigen in refining prostate cancer screening: From blood‑based tests to urinary and genetic markers (Review)

Luxi Li, Linyue Zhang, Zehong Li, Keqiang Chai, Weidong Ren
Article Number: 244
Published online on: 02 July 2026

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Nanocurcumin attenuates brain injury in rats with desert dry‑heat‑induced exertional heat stroke by suppressing TLR4/MyD88/NF‑κB signaling

Lisong Su, Jinquan Qu, Jiajia Li, Wenhui Shi, Laiyang Song, Feixing Liang, Jiangwei Liu
Article Number: 243
Published online on: 02 July 2026

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Review Open Access

TREM2 in glioma: Reprogramming the immune microenvironment from mechanistic understanding to clinical translation (Review)

Junqi Fan, Hongyan Shen, Dan Liu, Songbai Luo, Qingqing Huang, Yi Wen, Libang Yuan
Article Number: 242
Published online on: 02 July 2026

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Article Open Access

Human parvovirus B19 VP1u‑induced osteoclastogenesis is enhanced by RANKL in RAW264.7 macrophage cells

Chun-Yu Lin, Bor-Show Tzang, Yi-Hsuan Lin, Chih-Chen Tzang, Tsai-Ching Hsu
Article Number: 241
Published online on: 30 June 2026

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Retraction Open Access

[Retracted] Anti‑tumor peptide AP25 decreases cyclin D1 expression and inhibits MGC‑803 proliferation via phospho­extracellular signal‑regulated kinase‑, Src‑, c‑Jun N‑terminal kinase‑ and phosphoinositide 3­-kinase‑associated pathways  

Jialiang Hu, Tao Cheng, Lijun Zhang, Beicheng Sun, Lei Deng, Hanmei Xu
Article Number: 240
Published online on: 29 June 2026

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Aspirin prevents postoperative peritoneal adhesions by inhibiting the TGF‑β1/Smad signaling pathway in rats

Siqi Yan, Yuan Ren, Bingyan Liu, Pai Xiong, Yimin Sun
Article Number: 239
Published online on: 29 June 2026

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Morinda officinalis oligosaccharides ameliorate corticosterone‑induced depression‑like behaviour in mice by modulating the BDNF signalling pathway and gut microbiota

Mengjie He, Zixuan Liu, Yuxin Chen, Xiaoru Wu, Xueling Dai, Qian Liu, Shuo Wang, Zeping Zuo, Yaxuan Sun
Article Number: 238
Published online on: 29 June 2026

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Journal Cover
October-2026 Volume 34 Issue 4

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Journal Metrics

Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

UBE2A as a prognostic indicator across human cancers: Insights from multi‑omics and immune landscape analyses

Yun Wen, Pengfei Luo
Article Number: 260
Published online on: 23 July 2026

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