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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
March-2022 Volume 25 Issue 3

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

Pulsatilla decoction alleviates colitis by enhancing autophagy and regulating PI3K‑Akt‑mTORC1 signaling pathway

Xuewei Wang, Lijun Xu, Tao Wang, Jian Xu, Fugang Fan, Yu Zhang, Jinpin Wang, Qin Cao
Article Number: 108
Published online on: 31 January 2022

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Overexpression of Foxc1 ameliorates sepsis‑associated encephalopathy by inhibiting microglial migration and neuroinflammation through the IκBα/NF‑κB pathway

Hongyu Wang, Hongwei Wang, Yinsen Song, Congyan Liu, Xinling Qian, Dalong Zhang, Xin Jiang, Sisen Zhang
Article Number: 107
Published online on: 31 January 2022

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Article

Two PARP13 isoforms are associated with induction of antiviral factors in oral mucosal cells

Hiroki Kato, Kouji Ohta, Miyuki Sakuma, Shohei Fukada, Takako Naruse, Hideo Shigeishi, Hiromi Nishi, Masaaki Takechi
Article Number: 106
Published online on: 31 January 2022

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Correction Open Access

[Corrigendum] Transforming growth factor‑β1 induces fibrosis in rat meningeal mesothelial cells via the p38 signaling pathway

Xue-Jing Yue, Yan Guo, Hai-Jie Yang, Zhi-Wei Feng, Tong Li, Yu-Ming Xu
Article Number: 105
Published online on: 27 January 2022

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Article Open Access

Long noncoding RNA LINC00649 functions as a microRNA‑432‑5p sponge to facilitate tumourigenesis in colorectal cancer by upregulating HDGF

Junjie Bao, Xiaokai Bi, Jingbo Wang, Xiaoqiang Li
Article Number: 104
Published online on: 26 January 2022

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Dihydromyricetin ameliorates oxygen‑glucose deprivation and re‑oxygenation‑induced injury in HT22 cells by activating the Wnt/β‑catenin signaling pathway

Xiaoxiao Tao, Yaping Jiang, Xian Zheng, Xiaoxiao Ji, Feifei Peng
Article Number: 103
Published online on: 26 January 2022

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Article Open Access

GATA6‑induced FN1 activation promotes the proliferation, invasion and migration of oral squamous cell carcinoma cells

Jianbo Zhai, Gang Luo
Article Number: 102
Published online on: 26 January 2022

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Article Open Access

Knockdown of ATG4A inhibits breast cancer progression and promotes tamoxifen chemosensitivity by suppressing autophagy

Qingfang Li, Lingling Zan
Article Number: 101
Published online on: 25 January 2022

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Article Open Access

Pinus thunbergii bark extract rich in flavonoids promotes hair growth in dorsal skin by regulating inflammatory cytokines and increasing growth factors in mice

Young Her, Tae-Kyeong Lee, Hyejin Sim, Jae-Chul Lee, Dae Won Kim, Soo Young Choi, Jun Kee Hong, Ji-Won Lee, Jong-Dai Kim, Moo-Ho Won, Sung-Su Kim
Article Number: 100
Published online on: 25 January 2022

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Review Open Access

Cartilage tissue engineering: From proinflammatory and anti‑inflammatory cytokines to osteoarthritis treatments (Review)

Shuyu Liu, Zhenhan Deng, Kang Chen, Shengsheng Jian, Feifei Zhou, Yuan Yang, Zicai Fu, Huanyu Xie, Jianyi Xiong, Weimin Zhu
Article Number: 99
Published online on: 24 January 2022

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Atractylenolide III inhibits epithelial‑mesenchymal transition in small intestine epithelial cells by activating the AMPK signaling pathway

Mingjin Huang, Wenwen Jiang, Chunli Luo, Min Yang, Yan Ren
Article Number: 98
Published online on: 24 January 2022

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Retraction Open Access

[Retracted] MicroRNA‑145 inhibits the malignant phenotypes of gastric carcinoma cells via downregulation of fascin 1 expression

Minghui Xue, Lunde Zhao, Fang Yang, Zhenjuan Li, Guangyan Li
Article Number: 97
Published online on: 20 January 2022

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Protective effect of H2S on LPS‑induced AKI by promoting autophagy

Ting Li, Jie Zhao, Shuying Miao, Yiyang Chen, Yunfei Xu, Ying Liu
Article Number: 96
Published online on: 20 January 2022

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Article

FRAT1 promotes the angiogenic properties of human glioblastoma cells via VEGFA

Biao Yang, Dong Liu, Ye-Qing Ren, Yan-Qi Sun, Jian-Ping Zhang, Xiao-Gang Wang, Yong-Qiang Wu, Shu-Le Wang, Shi-Hao Guo, Geng Guo
Article Number: 95
Published online on: 20 January 2022

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Ginsenoside Rg3 protects glucocorticoid‑induced muscle atrophy in vitro through improving mitochondrial biogenesis and myotube growth

Ryuni Kim, Jee Won Kim, Sang-Jin Lee, Gyu-Un Bae
Article Number: 94
Published online on: 20 January 2022

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CpG site hypomethylation at ETS1‑binding region regulates DLK1 expression in Chinese patients with Tetralogy of Fallot

Guixiang Tian, Lili He, Ruoyi Gu, Jingwei Sun, Weicheng Chen, Yanyan Qian, Xiaojing Ma, Weili Yan, Zhenshan Zhao, Ziqing Xu, Meijiao Suo, Wei Sheng, Guoying Huang
Article Number: 93
Published online on: 20 January 2022

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Article Open Access

Nicotine promotes chronic obstructive pulmonary disease via inducing pyroptosis activation in bronchial epithelial cells

Rubing Mo, Jun Zhang, Yongxing Chen, Yipeng Ding
Article Number: 92
Published online on: 18 January 2022

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Article Open Access

Comparison of the effect of rotenone and 1‑methyl‑4‑phenyl‑1,2,3,6‑tetrahydropyridine on inducing chronic Parkinson's disease in mouse models

Jing Zhang, Bohao Sun, Jifeng Yang, Zhuo Chen, Zhengzheng Li, Nan Zhang, Hongzhi Li, Luxi Shen
Article Number: 91
Published online on: 17 January 2022

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Hyperbaric oxygen treatment improves pancreatic β‑cell function and hepatic gluconeogenesis in STZ‑induced type‑2 diabetes mellitus model mice

Caishun Zhang, Di Zhang, Haidan Wang, Qian Lin, Manwen Li, Junhua Yuan, Guangkai Gao, Jing Dong
Article Number: 90
Published online on: 17 January 2022

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Proteomic analysis of inhibitor of apoptosis protein‑like protein‑2 on breast cancer cell proliferation

Siqi Xiang, Lin Zhu, Zhiliang Zhang, Siyuan Wang, Ruxia Cui, Mingjun Xiang
Article Number: 89
Published online on: 17 January 2022

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Article Open Access

A cerebrospinal fluid microRNA analysis: Progressive supranuclear palsy

Wakako Nonaka, Tadayuki Takata, Hisakazu Iwama, Satoshi Komatsubara, Hideki Kobara, Masaki Kamada, Kazushi Deguchi, Tetsuo Touge, Osamu Miyamoto, Takehiro Nakamura, Toshifumi Itano, Tsutomu Masaki
Article Number: 88
Published online on: 14 January 2022

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Epigallocatechin gallate enhances human lens epithelial cell survival after UVB irradiation via the mitochondrial signaling pathway

Qiuxin Wu, Jike Song, Yan'e Gao, Yingying Zou, Junguo Guo, Xiuyan Zhang, Dongmei Liu, Dadong Guo, Hongsheng Bi
Article Number: 87
Published online on: 14 January 2022

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Long non‑coding RNA CTBP1‑AS2 upregulates USP22 to promote pancreatic carcinoma progression by sponging miR‑141‑3p

Mingliang Zhang, Songbo Ma, Xuzhao Li, Henghai Yu, Yizheng Tan, Jun He, Xiaoping Wei, Junming Ma
Article Number: 86
Published online on: 14 January 2022

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Article Open Access

RGMa regulates CCL5 expression via the BMP receptor in experimental autoimmune encephalomyelitis mice and endothelial cells

Shi Tang, Bao Su, Tao Tao, Weiping Yan, Rongrong Zhang, Xinyue Qin, Jinzhou Feng
Article Number: 85
Published online on: 13 January 2022

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Article Open Access

NOX4 stimulates ANF secretion via activation of the Sirt1/Nrf2/ATF3/4 axis in hypoxic beating rat atria

Zhi-Yu Li, Ying Liu, Yue-Ying Wang, Xiang Li, Zhuo-Na Han, Lan Hong, Ying-Shun Li, Xun Cui
Article Number: 84
Published online on: 13 January 2022

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Article Open Access

Total glucosides of paeony ameliorates oxidative stress, apoptosis and inflammatory response by regulating the Smad7‑TGF‑β pathway in allergic rhinitis

Yangzi Jin, Aichun Zhang
Article Number: 83
Published online on: 13 January 2022

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Article

Cellular response of lung fibroblasts and epithelial cells to particulate matter10 treatment examined via comparative transcriptome analysis

Kunhyang Park, Kwangho Kim, Tae Young Ryu, Jinkwon Lee, Moo-Seung Lee, Mi-Young Son, Seon-Jin Lee, Young-Jun Park, Hyun-Soo Cho, Dae-Soo Kim
Article Number: 82
Published online on: 13 January 2022

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Retraction Open Access

[Retracted] MicroRNA‑155 enhances the activation of Wnt/β‑catenin signaling in colorectal carcinoma by suppressing HMG‑box transcription factor 1

Ying-Chun Wan, Tao Li, Yang-Dong Han, Hai-Yan Zhang, Hai Lin, Bin Zhang
Article Number: 81
Published online on: 12 January 2022

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Synergetic protective effect of remote ischemic preconditioning and prolyl 4‑hydroxylase inhibition in ischemic cardiac injury

Juesheng Yang, Jiajun Xu, Lei Tao, Shiyong Wang, Haiyan Xiang, Yanhua Tang
Article Number: 80
Published online on: 11 January 2022

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B7‑H3 promotes the epithelial‑mesenchymal transition of NSCLC by targeting SIRT1 through the PI3K/AKT pathway

Haixiu Liao, Meng Ding, Nannan Zhou, Ying Yang, Liwen Chen
Article Number: 79
Published online on: 11 January 2022

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C‑X‑C receptor 7 agonist acts as a C‑X‑C motif chemokine ligand 12 inhibitor to ameliorate osteoclastogenesis and bone resorption

Alexander Patera Nugraha, Hideki Kitaura, Fumitoshi Ohori, Adya Pramusita, Saika Ogawa, Takahiro Noguchi, Aseel Marahleh, Yasuhiko Nara, Ria Kinjo, Itaru Mizoguchi
Article Number: 78
Published online on: 11 January 2022

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Survival‑related DLEU1 is associated with HPV infection status and serves as a biomarker in HPV‑infected cervical cancer

Aiping Dong, Bin Xu, Zhanzhao Wang, Xia Miao
Article Number: 77
Published online on: 10 January 2022

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Role of TGM2 in T‑cell lymphoblastic lymphoma via regulation of IL‑6/JAK/STAT3 signalling

Yuyan Wang, Ni Zheng, Tingting Sun, Hui Zhao, Ying Chen, Congcong Liu
Article Number: 76
Published online on: 10 January 2022

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Article

Long non‑coding RNA PCAT1 sponges miR‑134‑3p to regulate PITX2 expression in breast cancer

Weiming Tang, Guang Lu, Yin Ji, Yan Xu
Article Number: 75
Published online on: 10 January 2022

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Article Open Access

Dexmedetomidine alleviates airway hyperresponsiveness and allergic airway inflammation through the TLR4/NF‑κB signaling pathway in mice

Shilin Xiao, Qianyu Wang, Huibin Gao, Xumin Zhao, Juan Zhi, Dong Yang
Article Number: 74
Published online on: 10 January 2022

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Journal Cover
February-2026 Volume 33 Issue 2

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

ISX promotes tumor migration and invasion in lung cancer by upregulating COL1A1 in vitro

Yihe Ma, Ye Chen, Yuhui Liang, Yun Huang, Miao Gong, Lifeng Tian, Xiaojun Xiao, Jingyan Liu, Qinmiao Huang
Article Number: 77
Published online on: 31 December 2025

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Article Open Access

Role and mechanism of miR‑222‑5p in endothelial cell apoptosis

Shimeng Wang, Boxin Zhao, Ying Cui, Lin Gui, Jingyao Fan, Lijuan Huang
Article Number: 76
Published online on: 31 December 2025

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Expression of Concern Open Access

[Expression of Concern] MicroRNA-29c inhibits proliferation and promotes apoptosis in non-small cell lung cancer cells by targeting VEGFA

Shijuan Zhan, Chunfeng Wang, Fangqing Yin
Article Number: 75
Published online on: 22 December 2025

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Article Open Access

Melatonin induces autophagy in neuroblastoma by alleviating Pak2‑mediated endoplasmic reticulum stress

Qian-Qi Qiu, Na Zhang, Ying-Yi Xu, Jing-Wen Qin, Gao-Feng Yu, Xing-Rong Song
Article Number: 74
Published online on: 22 December 2025

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Article Open Access

ST3Gal1 modulates intestinal barrier function and impacts human ulcerative colitis

Yin Tian, Yun Liu, Yangyang Shang, Lijian Ran, Li Liu, Rongquan Wang, Jun Ye
Article Number: 73
Published online on: 18 December 2025

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Article Open Access

Mechanistic study of miR‑369‑3p in regulating the Wnt/β‑catenin signaling pathway via targeting SPTBN1 in inflammatory response and bone destruction of rheumatoid arthritis

Aihong Wu, Yuan Wang, Feifei Liu, Zhoufang Cao, Shuhui Du, Mengyu Sun
Article Number: 72
Published online on: 18 December 2025

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Article Open Access

CACNB1 alleviates mepivacaine‑induced myocardial ischemia/reperfusion injury by promoting Nrf2 nuclear translocation

Qingbo Shao, Ji Zhang, Huaying Wang
Article Number: 71
Published online on: 17 December 2025

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Expression of Concern Open Access

[Expression of Concern] Effects of cullin 4B on the proliferation and invasion of human gastric cancer cells

Feng He, Xiu-Mei Cheng, Wen-Long Gu
Article Number: 70
Published online on: 17 December 2025

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Article Open Access

Aggravated effects of human parvovirus B19 NS1 protein on bleomycin‑induced pulmonary fibrosis

Tsai-Ching Hsu, Chih-Chen Tzang, Chia-Wei Kuo, Zhi-Han Wen, Der-Yuan Chen, Bor-Show Tzang
Article Number: 69
Published online on: 16 December 2025

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Review Open Access

Advances regarding the mechanism of endoplasmic reticulum stress in diabetic kidney disease and pharmacological interventions (Review)

Pai Zhang, Yabin Cui, Chunyan Liu, Chengji Cui, Shoulin Zhang, Yue Zhang, Fan Li
Article Number: 68
Published online on: 16 December 2025

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Retraction Open Access

[Retracted] N‑Myc downstream‑regulated gene 2 suppresses the proliferation of T24 human bladder cancer cells via induction of oncosis

Jie Huang, Zhou Wu, Guangxiu Wang, Yingxian Cai, Minshan Cai, Yaozhang Li
Article Number: 67
Published online on: 15 December 2025

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Review Open Access

Deciphering epigenetic regulation in cardiac developmental toxicity: Mechanisms and implications (Review)

Ziling Qin, Ranran Chen, Dianrong Song
Article Number: 66
Published online on: 11 December 2025

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Review Open Access

Gut microbiota as a multifaceted modulator of prostate cancer: Mechanistic insights, therapeutic opportunities and clinical challenges (Review)

Zhenming Hao, Yongqiang Xie, Ru Zhang, Hui Sang, Luxi Li, Yulin Liu, Jinbo Hu, Jijun Wang, Keqiang Chai, Qiang Zhao
Article Number: 65
Published online on: 11 December 2025

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Expression of Concern Open Access

[Expression of Concern] lncRNA FLVCR1‑AS1 drives colorectal cancer progression via modulation of the miR‑381/RAP2A axis

Yi Han, Xiaoyan Wang, Enqiang Mao, Boyong Shen, Liang Huang
Article Number: 64
Published online on: 10 December 2025

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Review Open Access

Influence and treatment of insulin receptor substrate/PI3K/Akt‑mediated insulin resistance in diabetes mellitus (Review)

Weikang Tang, Huixia Liu, Xuan Li, Siyao Deng, Changyu Gao
Article Number: 63
Published online on: 09 December 2025

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Retraction Open Access

[Retracted] Long non‑coding RNA ANRIL knockdown suppresses apoptosis and pro‑inflammatory cytokines while enhancing neurite outgrowth via binding microRNA‑125a in a cellular model of Alzheimer’s disease

Bingling Zhou, Lijuan Li, Xin Qiu, Jiashun Wu, Lei Xu, Wei Shao
Article Number: 62
Published online on: 08 December 2025

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Review Open Access

Mitophagy and oxidative stress in chronic kidney disease (Review)

Quwu Mushuo, Yihuai Tian, Jianchun Li, Yanqin Qiu, Hui Fan, Qiongdan Hu, Qiong Zhang
Article Number: 61
Published online on: 04 December 2025

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Article Open Access

ABCC9 knockdown attenuates isoproterenol‑induced myocardial hypertrophy by inhibiting the PI3K/AKT signaling pathway

Qian Peng, Rui Chang, Linlin Ma, Yanfei Li
Article Number: 60
Published online on: 04 December 2025

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Article

MeCP2 suppresses ferroptosis to drive EMT in retinal pigment epithelial cells: Implications for PVR pathogenesis

Sibei Guo, Yongya Zhang, Xue Li, Xueru Zhao, Yingjuan Liang, Xiaohua Li
Article Number: 59
Published online on: 04 December 2025

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Correction Open Access

[Corrigendum] Screening for implicated genes in colorectal cancer using whole‑genome gene expression profiling

Long-Ci Sun, Hai-Xin Qian
Article Number: 58
Published online on: 04 December 2025

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Article Open Access

Hyperoside prevents osteoporosis by activating the PI3K/AKT signaling pathway to inhibit oxidative stress and promote osteogenesis

Lirong Li, Huaidong Deng, Shabin Zhuan, Boyu Wu, Dawei Xiao
Article Number: 57
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Interference with Tim‑3 protein expression attenuates the invasion of clear cell renal cell carcinoma and aggravates anoikis

Muming Yu, Bin Lu, Yancun Liu, Ying Me, Lijun Wang, Hui Li
Article Number: 56
Published online on: 01 December 2025

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Article Open Access

Acetylshikonin induces ferroptosis via the lipid peroxidation pathway in osteosarcoma cells

Ji-Ying Chen, Guo-Shou Wang, Tsung-Ming Chang, Ju-Fang Liu
Article Number: 55
Published online on: 27 November 2025

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Review Open Access

Liver X receptor: A potential target for inflammatory bowel disease and colorectal cancer (Review)

Yingjie Li, Xiaoyan Fu, Meiwen Bai, Jiaqi Zhou, Jiatai Qiu, Hongxia Zhang, Shujuan Liang, Meifang Liu
Article Number: 54
Published online on: 27 November 2025

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Article Open Access

lncRNA NEAT1 promotes the proliferation of hemangioma cells by transcriptionally activating β‑catenin via enhancing H3K18 lactylation

Li Yu, Nian Zhou, Xiao-Liang Zhang, Xue-Jing Pang, Lu Xing, Yun-Jing Pu, Li Zhang, Jing-Nan Wu, Hong Shu
Article Number: 53
Published online on: 25 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑206 exerts anti‑oncogenic functions in esophageal squamous cell carcinoma by suppressing the c‑Met/AKT/mTOR pathway

Jin Zhang, Xianen Fa, Qingyong Zhang
Article Number: 52
Published online on: 25 November 2025

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March-2026 Volume 33 Issue 3

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Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

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Published online on: 05 January 2026

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[Retracted] TIPE‑2 suppresses growth and aggressiveness of hepatocellular carcinoma cells through downregulation of the phosphoinositide 3‑kinase/AKT signaling pathway

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Article Number: 78
Published online on: 05 January 2026

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