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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
February-2023 Volume 27 Issue 2

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

Development and validation of a novel ferroptosis‑related lncRNA prognostic signature for pancreatic adenocarcinoma

Jian Li, Wenhua Li, Huaizhi Wang, Bing Ni, Yongkang Liu
Article Number: 56
Published online on: 18 January 2023

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Article Open Access

Differential methylation of circRNA m6A in an APP/PS1 Alzheimer's disease mouse model

Xiao Zhang, Suge Yang, Song Han, Yuan Sun, Min Han, Xiaolei Zheng, Fan Li, Yan Wei, Yun Wang, Jianzhong Bi
Article Number: 55
Published online on: 18 January 2023

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Article Open Access

Evaluation of the antioxidant potency of Greek honey from the Taygetos and Pindos mountains using a combination of cellular and molecular methods

Anastasia Patouna, Periklis Vardakas, Zoi Skaperda, Demetrios A. Spandidos, Demetrios Kouretas
Article Number: 54
Published online on: 18 January 2023

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Article Open Access

Ubiquitin D promotes the progression of rheumatoid arthritis via activation of the p38 MAPK pathway

Hong Chen, Liju Tao, Juhua Liang, Chunfeng Pan, Hua Wei
Article Number: 53
Published online on: 18 January 2023

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Article Open Access

STEAP1 regulation and its influence modulating the response of LNCaP prostate cancer cells to bicalutamide, enzalutamide and apalutamide

Sandra M. Rocha, Daniel Nascimento, Ana Margarida Cardoso, Luís Passarinha, Sílvia Socorro, Cláudio J. Maia
Article Number: 52
Published online on: 13 January 2023

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Article Open Access

Rhododendrol, a reductive metabolite of raspberry ketone, suppresses the differentiation of 3T3‑L1 cells into adipocytes

Naoto Uramaru, Azusa Kawashima, Makoto Osabe, Toshiyuki Higuchi
Article Number: 51
Published online on: 11 January 2023

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Article Open Access

SPARC is a decoy counterpart for c‑Fos and is associated with osteoblastic differentiation of bone marrow stromal cells by inhibiting adipogenesis

Tomoya Hatori, Toyonobu Maeda, Atsuko Suzuki, Keiso Takahashi, Yasumasa Kato
Article Number: 50
Published online on: 10 January 2023

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Retraction Open Access

[Retracted] MicroRNA‑708 inhibits the proliferation and invasion of osteosarcoma cells by directly targeting ZEB1

Jun He, Deng Xiang, Yanshui Lin
Article Number: 49
Published online on: 09 January 2023

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Article Open Access

Prognostic value of NOX2 as a potential biomarker for lung adenocarcinoma using TCGA and clinical validation

Yingjie Liu, Di Han, Qihui Ma, Yuanhang Zheng, Yi Lin, Chunqing Yang, Lun Yang
Article Number: 48
Published online on: 09 January 2023

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Article Open Access

ASK1 inhibitor NQDI‑1 decreases oxidative stress and neuroapoptosis via the ASK1/p38 and JNK signaling pathway in early brain injury after subarachnoid hemorrhage in rats

Jiajia Duan, Wen Yuan, Juan Jiang, Jikai Wang, Xiaoxin Yan, Fei Liu, Aihua Liu
Article Number: 47
Published online on: 09 January 2023

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Article

Evaluation of the proteomic landscape of HPV E7‑induced alterations in human keratinocytes reveal therapeutically relevant pathways for cervical cancer

Sivasangkary Gandhi, Muhammad Fazril Mohamad Razif, Shatrah Othman, Sajib Chakraborty, Nurshamimi Nor Rashid
Article Number: 46
Published online on: 09 January 2023

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Article Open Access

Glycyrrhizin regulates the HMGB1/P38MAPK signalling pathway in status epilepticus

Zhong Luo, Meng Xu, Linhai Zhang, Haiqing Zhang, Zucai Xu, Zhongxiang Xu
Article Number: 45
Published online on: 05 January 2023

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Article Open Access

Oxysophoridine protects against cerebral ischemia/reperfusion injury via inhibition of TLR4/p38MAPK‑mediated ferroptosis

Jing Zhao, Mingming Ma, Lei Li, Gaoli Fang
Article Number: 44
Published online on: 04 January 2023

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Retraction Open Access

[Retracted] MicroRNA‑629 inhibition suppresses the viability and invasion of non‑small cell lung cancer cells by directly targeting RUNX3

Bufeng Zhuang, Youshuang Cheng
Article Number: 43
Published online on: 03 January 2023

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Article Open Access

Role of SUMOylation of STAT1 in tubular epithelial‑mesenchymal transition induced by high glucose

Cunyang Gu, Feng Gao, Shiqi Zhang, Lihua Kang, Wei Zhang, Xiaojuan Feng, Jinxi Liu, Yuexin Tian, Qun Wei, Yunxia Du, Yujia Xing, Qingjuan Liu, Shuxia Liu
Article Number: 42
Published online on: 02 January 2023

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Article

Isofraxidin enhances hyperthermia‑induced apoptosis via redox modification in acute monocytic leukemia U937 cells

Peng Li, Qing-Li Zhao, Mati Ur Rehman, Paras Jawaid, Zheng-Guo Cui, Kanwal Ahmed, Takashi Kondo, Jun-Ichi Saitoh, Kyo Noguchi
Article Number: 41
Published online on: 02 January 2023

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Article Open Access

miRNA‑92a inhibits vascular smooth muscle cell phenotypic modulation and may help prevent in‑stent restenosis

Fenfen Jiang, Bin Zhang, Xiangyu Zhang, Ran Zhang, Qin Lu, Fengjie Shi, Jianjiang Xu, Lang Deng
Article Number: 40
Published online on: 02 January 2023

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Article Open Access

Nerve growth factor causes epinephrine release dysfunction by regulating phenotype alterations and the function of adrenal medullary chromaffin cells in mice with allergic rhinitis

Chao Liu, Jian-Ping Liang, Xiao-Lin Huang, Zhong Liu, An-Bing Zhang, Nian-Gen Deng, Zi-Feng Wei, Jun Wang
Article Number: 39
Published online on: 02 January 2023

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Article Open Access

An angiogenesis‑related lncRNA signature for the prognostic prediction of patients with bladder cancer and LINC02321 promotes bladder cancer progression via the VEGFA signaling pathway

Zhao Kang, Qian Dou, Ting Huang, Maoting Tu, Yongping Zhong, Mei Wang, Tao Li
Article Number: 38
Published online on: 29 December 2022

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Article Open Access

Combination of chloroquine diphosphate and salidroside induces human liver cell apoptosis via regulation of mitochondrial dysfunction and autophagy

Bing Jiang, Longfei Feng, Tao Yang, Wenjing Guo, Yangyang Li, Tao Wang, Chengguang Liu, Haixiang Su
Article Number: 37
Published online on: 27 December 2022

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Retraction Open Access

[Retracted] MicroRNA‑601 serves as a potential tumor suppressor in hepatocellular carcinoma by directly targeting PIK3R3

Yanan Song, Saifei He, Juhua Zhuang, Guoyu Wang, Jing Ni, Suiliang Zhang, Ying Ye, Wei Xia
Article Number: 36
Published online on: 22 December 2022

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Review Open Access

Role of the AMPK/SIRT1 pathway in non‑alcoholic fatty liver disease (Review)

Putri Anggreini, Hadi Kuncoro, Sri Adi Sumiwi, Jutti Levita
Article Number: 35
Published online on: 21 December 2022

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Review

FOXO3 is a potential biomarker and therapeutic target for premature ovarian insufficiency (Review)

Xingqi Meng, Lixuan Peng, Xing Wei, Suyun Li
Article Number: 34
Published online on: 20 December 2022

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Article Open Access

MicroRNA‑194‑5p attenuates hypoxia/reoxygenation‑induced apoptosis in H9C2 cardiomyocytes by inhibiting the over‑activation of RAC1 protein

Cuie Li, Yinghua Li, Yanping Li, Yudi Wang, Yirong Teng, Yinglu Hao
Article Number: 33
Published online on: 20 December 2022

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Correction Open Access

[Corrigendum] Comparison of the biological characteristics of human mesenchymal stem cells derived from exfoliated deciduous teeth, bone marrow, gingival tissue, and umbilical cord

Jing Li, Shi-Qing Xu, Yu-Ming Zhao, Shi Yu, Li-Hong Ge, Bao-Hua Xu
Article Number: 32
Published online on: 19 December 2022

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Article Open Access

DCXR promotes cell proliferation by promoting the activity of aerobic glycolysis in breast cancer

Yongmei Jin, Miao Zhang, Yang Tong, Lin Qiu, Ying Ye, Bin Zhao
Article Number: 31
Published online on: 16 December 2022

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Article Open Access

S100A1 expression is increased in spinal cord injury and promotes inflammation, oxidative stress and apoptosis of PC12 cells induced by LPS via ERK signaling

Ye Bai, Ning Guo, Zhanwu Xu, Yuxi Chen, Wenjin Zhang, Qinghe Chen, Zhenggang Bi
Article Number: 30
Published online on: 13 December 2022

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Retraction Open Access

[Retracted] MicroRNA‑18b acts as an oncogene in gastric cancer by directly targeting Kruppel‑like factor 6

Dongming Luo, Junqiang Chen, Shifeng Huang, Junyi Xu, Xuemin Song, Pengcheng Yu
Article Number: 29
Published online on: 13 December 2022

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Article Open Access

WNT5A, β‑catenin and SUFU expression patterns, and the significance of microRNA deregulation in placentas with intrauterine growth restriction

Ida Marija Sola, Valentina Karin-Kujundzic, Frane Paic, Lada Lijovic, Mislav Glibo, Nikola Serman, Tihana Duic, Anita Skrtic, Krunoslav Kuna, Semir Vranic, Ljiljana Serman
Article Number: 28
Published online on: 13 December 2022

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Article Open Access

ANRIL overexpression globally induces expression and alternative splicing of genes involved in inflammation in HUVECs

Alimu Wufuer, Xiemusiye Luohemanjiang, Lei Du, Jing Lei, Mayila Shabier, Deng Feng Han, Jianhua Ma
Article Number: 27
Published online on: 13 December 2022

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Sodium arsenite and dimethylarsenic acid induces apoptosis in OC3 oral cavity cancer cells

Su-Zhen Wu, Yu-Yan Lan, Chiao-Yun Chu, Yi-Ping Lee, Hong-Yi Chang, Bu-Miin Huang
Article Number: 26
Published online on: 13 December 2022

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Correction Open Access

[Corrigendum] lncRNA DQ786243 promotes hepatocellular carcinoma cell invasion and proliferation by regulating the miR‑15b‑5p/Wnt3A axis

Zewei Lin, Jikui Liu
Article Number: 25
Published online on: 09 December 2022

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Article Open Access

Absence of indoleamine 2,3‑dioxygenase 2 promotes liver regeneration after partial hepatectomy in mice

Tatsuya Ando, Masato Hoshi, Hiroyuki Tezuka, Hiroyasu Ito, Kentaro Nakamoto, Yasuko Yamamoto, Kuniaki Saito
Article Number: 24
Published online on: 08 December 2022

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Retraction Open Access

[Retracted] MicroRNA‑509 targets PAX6 to inhibit cell proliferation and invasion in papillary thyroid carcinoma

Shuilong Zhang, Qiang Wang, Dewei Li, Bo Huang, Xia Hou, Dongliang Wang
Article Number: 23
Published online on: 08 December 2022

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Correction Open Access

[Corrigendum] Gene silencing of NOB1 by lentivirus suppresses growth and migration of human osteosarcoma cells

Bingpeng Chen, Jingjing Liu, Dankai Wu, Yanguo Qin, Chuangang Peng, Chen Li, Jincheng Wang
Article Number: 22
Published online on: 06 December 2022

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Article Open Access

G9a inhibition promotes the formation of pacemaker-like cells by reducing the enrichment of H3K9me2 in the HCN4 promoter region

Pei Xu, Kai Jin, Jing Zhou, Jiangun Gu, Xiang Gu, Lijuan Dong, Xiaolin Sun
Article Number: 21
Published online on: 05 December 2022

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Journal Cover
March-2026 Volume 33 Issue 3

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article

CTRP4 ameliorates dexamethasone‑induced insulin resistance through the IRS‑1/PI3K/AKT pathway in 3T3‑L1 adipocytes

Maireyanmu Rouzi, Xi Sun, Luguang Sheng, Bilin Xu, Tao Lei, Jun Lu, Jie Gao
Article Number: 101
Published online on: 27 January 2026

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PTUPB, a soluble epoxide hydrolase/cyclooxygenase‑2 dual inhibitor, reduces endothelial‑to‑mesenchymal transition and improves doxorubicin‑induced vascular and cardiac toxicity

Hevna Dhulkifle, Lubna Therachiyil, Maram H. Hasan, Shahd M. Younis, Nizar A. Al‑Shar'i, Huseyin C. Yalcin, Zaid H. Maayah
Article Number: 100
Published online on: 27 January 2026

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Retraction Open Access

[Retracted] miR‑367 enhances the proliferation and invasion of cutaneous malignant melanoma by regulating phosphatase and tensin homolog expression

Jianwen Long, Jing Luo, Xuwen Yin
Article Number: 99
Published online on: 26 January 2026

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Advances in the mechanisms of the NLRP3 inflammasome in sepsis‑induced cardiomyopathy and targeted therapeutic studies 
(Review)

Yifei Chen, Zhaohui Zhang, Gaosheng Zhou
Article Number: 98
Published online on: 22 January 2026

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Article Open Access

HMGN2 induces pyroptosis in tumour cells by modulating the STT3B/PD‑L1/caspase‑1/GSDMD axis

Wenwen Han, Hongli Chen, Bomiao Cui, Jiao Chen, Ping Zhang, Yun Feng
Article Number: 97
Published online on: 22 January 2026

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Article Open Access

Naringin ameliorates intestinal injury in ulcerative colitis model mice by modulating the JAK2/STAT3 signaling pathway

Miaomiao Wu, Yating An, Yongmin Li, Wei He, Ying Wang, Yaqi Wang, Caixia Wu
Article Number: 96
Published online on: 22 January 2026

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Review

PDX1 in human cancers: Molecular mechanisms, dual roles and clinical implications (Review)

Chen Zhou, Yifei Wang, Jie Zhao, Yantao Yang, Yuhang Yuan, Xiaochen Hou, Yu Tang, Lianhua Ye
Article Number: 95
Published online on: 22 January 2026

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Retraction Open Access

[Retracted] Autophagy flux inhibition mediated by celastrol sensitized lung cancer cells to TRAIL‑induced apoptosis via regulation of mitochondrial transmembrane potential and reactive oxygen species

Uddin Md Nazim, Honghua Yin, Sang-Youel Park
Article Number: 94
Published online on: 19 January 2026

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Review Open Access

Converting ‘cold’ to ‘hot’ hepatocellular carcinoma for improved immunotherapy (Review)

Ching-Hua Hsieh, Pei-Chin Chuang
Article Number: 93
Published online on: 15 January 2026

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Article Open Access

Pathological mechanism of ferroptosis in a rat model of α‑naphthyl isothiocyanate‑induced chronic cholestasis

Zhen Guo, Jiaxuan Wang, Yiwen Wang, Xinzhu Liu, Yubing Xia, Ping Liu, Li Qi, Jia Liu, Xiaoning Wang
Article Number: 92
Published online on: 14 January 2026

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Correction Open Access

[Corrigendum] Role of hypoxia‑inducible factor‑1α and CD146 in epidermal growth factor receptor‑mediated angiogenesis in salivary gland adenoid cystic carcinom

Wei-Ming Wang, Zhi-Li Zhao, Wen-Feng Zhang, Yi-Fang Zhao, Lu Zhang, Zhi-Jun Sun
Article Number: 91
Published online on: 13 January 2026

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Review Open Access

Klebsiella pneumoniae and pyogenic liver abscess: Emerging clinical threats, virulence mechanisms and therapeutic strategies (Review)

Gulam Mustafa Hasan, Taj Mohammad, Sobia Zaidi, Anas Shamsi, Sukhwinder Singh Sohal, Md. Imtaiyaz Hassan
Article Number: 90
Published online on: 13 January 2026

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Article Open Access

Collagen III regulates the termination of liver regeneration by suppressing hepatocyte proliferation and promoting functional recovery

Haiyang Peng, Zhiyong Chen, Qiwei Zhang, Yuezhou Zhang, Peng Yang, Jianping Gong, Andong Zhao
Article Number: 89
Published online on: 13 January 2026

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Review Open Access

Application of extracellular vesicles in the diagnosis and treatment of chronic obstructive pulmonary disease (Review)

Yixin Zhang, Tong Ren, Jianbo Xue, Yan Yu, Xianqiang Zhou, Xiaoyi Hu, Wenyi Yu, Zhancheng Gao, Cuiling Feng
Article Number: 88
Published online on: 13 January 2026

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Article Open Access

Cigarette smoke combined with Klebsiella pneumoniae induce damage to the air‑blood barrier in chronic obstructive pulmonary disease rats via the MAPK/NF‑κB/IκBα pathway

Yange Tian, Kexin Xu, Ruilong Lu, Kangchen Li, Xuejie Shao, Yixi Liao, Yakun Zhao, Zhiguang Qiu, Haoran Dong, Xuefang Liu
Article Number: 87
Published online on: 12 January 2026

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Retraction Open Access

[Retracted] 8‑bromo‑7‑methoxychrysin induces apoptosis by regulating Akt/FOXO3a pathway in cisplatin‑sensitive and resistant ovarian cancer cells

Qing Ding, Yi Chen, Qing Zhang, Yanling Guo, Zhi Huang, Liqing Dai, Sudan Cao
Article Number: 86
Published online on: 12 January 2026

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Article Open Access

Anxiety‑induced overactive bladder: The role of oxidative stress and NF‑κB signaling pathway with Hsp90 as a potential biomarker

Zhipeng Zhou, Lina Xu, Han Wu, Huaishan Hong
Article Number: 85
Published online on: 12 January 2026

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Article Open Access

Echinacoside alleviates asthenozoospermia by upregulating Sox5‑mediated transcriptional activation of the CatSper gene

Zi-Run Jin, Yong-Wei Huo, Bo-Heng Liu, Hong Tian, Shuo Yuan, Yue Tian, Ke Xi, Jie Cai, Hui Jiang, Yong Jiang, Guo-Gang Xing
Article Number: 84
Published online on: 12 January 2026

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Article Open Access

Artemisiae Scopariae Herba (Yinchen) suppresses ferroptosis in mice with osteoporosis via the Nrf2/Slc7a11/Gpx4 pathway

Pei Li, Xinyu Wan, Wenjie Li, Ding Cheng, Ying Yang, Yuhan Wang, Ruyuan Zhu, Yanjing Chen, Haixia Liu, Zhiguo Zhang
Article Number: 83
Published online on: 12 January 2026

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Review Open Access

Prolyl hydroxylase domain proteins: Localization, regulation, function and their role in erythropoiesis (Review)

Yan Hou, Zhao-Hua Zhang, Wen-Qian Li, Guo-Xiong Han, Kuo Shen, You-Bang Xie
Article Number: 82
Published online on: 12 January 2026

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Therapeutic potential of saponins for allergic rhinitis: Molecular mechanisms and clinical perspectives (Review)

Bing-Yu Liang, Zi-Yue Fu, Fen-Fen Li, Ping-Ting Zhou, Zi-Hui Xie, Ke Han, Yan-Xun Han, Shan-Wen Chen, Yi Zhao, Hai-Feng Pan, Ye-Hai Liu, Yu-Chen Liu
Article Number: 81
Published online on: 07 January 2026

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Interleukin‑6 and ischemic stroke: From mechanisms to clinical prospects (Review)

Xinyue Wang, Xiaohang Zhang, Jianing Lin, Ping Lin
Article Number: 80
Published online on: 05 January 2026

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Article Open Access

Preliminary exploration of the putative function of SF3A2 in clear cell renal cell carcinoma

Ru Chen, Jie Xu
Article Number: 79
Published online on: 05 January 2026

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Retraction Open Access

[Retracted] TIPE‑2 suppresses growth and aggressiveness of hepatocellular carcinoma cells through downregulation of the phosphoinositide 3‑kinase/AKT signaling pathway

Lin Wang, Chen Chen, Shuzhi Feng, Jianli Tian
Article Number: 78
Published online on: 05 January 2026

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April-2026 Volume 33 Issue 4

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Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

Integrative bioinformatics and experimental analysis reveals FRA1 as a key mediator of tubulointerstitial inflammation in lupus nephritis

Wenpeng Ni, Jialin He, Zhouyu Zeng, Jialong Ke, Runpei Lin, Jianming Peng, Kunyi Deng, Lijuan Wen, Yanhui Chen, Chilun Zhang, Yanfen Li, Guanghong Gu
Article Number: 103
Published online on: 28 January 2026

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Correction Open Access

[Corrigendum] Resveratrol improves neurological outcome and neuroinflammation following spinal cord injury through enhancing autophagy involving the AMPK/mTOR pathway

Hong-Yu Meng, De-Cheng Shao, Han Li, Xiao-Dan Huang, Guang Yang, Bing Xu, Hai-Yun Niu
Article Number: 102
Published online on: 28 January 2026

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