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Molecular Medicine Reports
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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
2014-February Volume 9 Issue 2

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article

Loss of ASAP3 destabilizes cytoskeletal protein ACTG1 to suppress cancer cell migration

Yu Luo, Fang Kong, Zhen Wang, Dahan Chen, Qiuyan Liu, Tao Wang, Ruian Xu, Xianyuan Wang, James Y. Yang
Pages: 387-394
Published online on: 27 November 2013

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Article Open Access

Protective effect of ginsenoside Rg1 on lidocaine-induced apoptosis

Hui Li, Junmei Xu, Xin Wang, Guixiu Yuan
Pages: 395-400
Published online on: 21 November 2013

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Article

ω-3 polyunsaturated fatty acids inhibit the proliferation of the lung adenocarcinoma cell line A549 in vitro

Qing-Hua Yao, Xiao-Chen Zhang, Ting Fu, Jian-Zhong Gu, Lu  Wang, Yun Wang, Yue-Biao Lai, Yu-Qi Wang, Yong Guo
Pages: 401-406
Published online on: 26 November 2013

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Article Open Access

Role of prenatal undernutrition in the expression of serotonin, dopamine and leptin receptors in adult mice: Implications of food intake

Leticia Manuel‑Apolinar, Luisa Rocha, Leticia Damasio, Emiliano Tesoro‑Cruz, Arturo Zarate
Pages: 407-412
Published online on: 10 December 2013

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Article

Fisetin inhibits migration, invasion and epithelial-mesenchymal transition of LMP1-positive nasopharyngeal carcinoma cells Retraction in /10.3892/mmr.2025.13628

Rong Li, Yinhai Zhao, Jin Chen, Songjun Shao, Xiujuan Zhang
Pages: 413-418
Published online on: 02 December 2013

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Article Open Access

Effect of dexmedetomidine on lung ischemia‑reperfusion injury

Lili Jiang, Li Li, Jinmei Shen, Zeyou Qi, Liang Guo
Pages: 419-426
Published online on: 17 December 2013

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Article Open Access

Effect of lipopolysaccharide on the characteristics of endothelial progenitor cells from bone marrow in mice

Hao Li, Yong Qiang, Lian Wang, Canhui Liu, Nan Yang, Lei Xiong, Jun Yi, Hua Jing, Haiwei Wu
Pages: 427-434
Published online on: 28 November 2013

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Article Open Access

Quercetin reduces oxidative stress and inhibits activation of c‑Jun N‑terminal kinase/activator protein‑1 signaling in an experimental mouse model of abdominal aortic aneurysm

Lian Wang, Xiaofeng Cheng, Hao Li, Fang Qiu, Nan Yang, Bo  Wang, Huchen Lu, Haiwei Wu, Yi Shen, Yanqing Wang, Hua Jing
Pages: 435-442
Published online on: 06 December 2013

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Article Open Access

Valproic acid inhibits tumor angiogenesis in mice transplanted with Kasumi‑1 leukemia cells

Zhi‑Hua Zhang, Chang‑Lai Hao, Peng Liu, Xia Tian, Li‑Hong Wang, Lei Zhao, Cui‑Min Zhu
Pages: 443-449
Published online on: 28 November 2013

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Article

High glucose induces activation of the local renin‑angiotensin system in glomerular endothelial cells

Hui Peng, Yan‑Fang Xing, Zeng‑Chun Ye, Can‑Ming Li, Peng‑Li Luo, Ming Li, Tan‑Qi Lou
Pages: 450-456
Published online on: 10 December 2013

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Article

Nephrin and Podocin functions are highly conserved between the zebrafish pronephros and mammalian metanephros

Yayoi Fukuyo, Tomomi Nakamura, Ekaterina Bubenshchikova, Rebecca Powell, Takashi Tsuji, Ralf Janknecht, Tomoko Obara
Pages: 457-465
Published online on: 06 December 2013

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Article Open Access

Compound heterozygous hemophilia A in a female patient and the identification of a novel missense mutation, p.Met1093Ile

Shu-Kai Qiao, Han-Yun Ren, Jin-Hai Ren, Xiao-Nan Guo
Pages: 466-470
Published online on: 04 December 2013

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Article

Expression, purification and characterization of a recombinant Tat47-57-Oct4 fusion protein in Pichia pastoris

Haotian Wang, Xinmin Zhang, Ning Kong, Anhui Wei, Yanhong Zhang, Jie Ma, Yulai Zhou, Weiqun Yan
Pages: 471-475
Published online on: 11 December 2013

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Article

Carnosol inhibits cell adhesion molecules and chemokine expression by tumor necrosis factor-α in human umbilical vein endothelial cells through the nuclear factor-κB and mitogen-activated protein kinase pathways

Hui Yao, Yufeng Chen, Longjuan Zhang, Xiaosheng He, Xiaowen He, Lei Lian, Xiaojian Wu, Ping Lan
Pages: 476-480
Published online on: 03 December 2013

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Article

Early-onset severe hereditary sensory and autonomic neuropathy type 1 with S331F SPTLC1 mutation

Bum Chun Suh, Young Bin Hong, Khriezhanuo Nakhro, Soo Hyun Nam, Ki Wha Chung, Byung-Ok Choi
Pages: 481-486
Published online on: 18 November 2013

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Article

The long-term effects of splenectomy and subsequent interferon therapy in patients with HCV-related liver cirrhosis

Yuji Inagaki, Kazushi Sugimoto, Katsuya Shiraki, Masahiko Tameda, Satoko Kusagawa, Keiichiro Nojiri, Suguru Ogura, Norihiko Yamamoto, Yoshiyuki Takei, Masaaki Ito, Shugo Mizuno, Masanobu Usui, Hiroyuki Sakurai, Shuji Isaji
Pages: 487-492
Published online on: 11 December 2013

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Article

Melatonin protects MG63 osteoblast-like cells from hydrogen peroxide-induced cytotoxicity by maintaining mitochondrial function

Fei She, Wenbo Wang, Yan Wang, Peifu Tang, Junqiang Wei, Hua Chen, Boxun Zhang
Pages: 493-498
Published online on: 28 November 2013

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Article

Capsaicin induces apoptosis and modulates MAPK signaling in human gastric cancer cells

Seon-Young Park, Ji-Young Kim, Su-Mi Lee, Chung-Hwan Jun, Sung-Bum Cho, Chang-Hwan Park, Young‑Eun Joo, Hyun-Soo Kim, Sung-Kyu Choi, Jong-Sun Rew
Pages: 499-502
Published online on: 09 December 2013

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Article

MicroRNA-203 inhibits the proliferation and invasion of U251 glioblastoma cells by directly targeting PLD2 Retraction in /10.3892/mmr.2023.13154

Zigui Chen, Dazhi Li, Quan Cheng, Zhiming Ma, Bing Jiang, Renjun Peng, Rui Chen, Yiqiang Cao, Xin Wan
Pages: 503-508
Published online on: 20 November 2013

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Article

Protective effect of donepezil hydrochloride on cerebral ischemia/reperfusion injury in mice

Tianjun Wang, Peiyuan Lv, Wei Jin, Hezhen Zhang, Jingfang Lang, Mingyue Fan
Pages: 509-514
Published online on: 22 November 2013

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Article

Cytotoxicity study on SH‑SY5Y cells cultured at high glucose levels and treated with bupivacaine

Yawen Li, Shiyuan Xu, Qingguo Zhang, Le Li, Luying Lai, Ting Zheng, Jiaoling Su, Naimei Yang, Yuantao Li
Pages: 515-520
Published online on: 06 December 2013

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Article

Crocetin induces apoptosis of BGC-823 human gastric cancer cells Corrigendum in /10.3892/mmr.2023.13038

Ke He, Picheng Si, Hanning Wang, Usman Tahir, Kaiyun Chen, Jinfeng Xiao, Xiaopeng Duan, Rui Huang, Guoan Xiang
Pages: 521-526
Published online on: 09 December 2013

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Article

Dexamethasone‑induced hyposensitivity to rocuronium in rat diaphragm associated with muscle‑fiber transformation

Dan Chen, Mei‑Rong Yang, Li‑Na Huang, Yu‑Wei Qiu, Shi‑Tong Li
Pages: 527-534
Published online on: 20 November 2013

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Article

Analysis of transcription factor Stk40 expression and function during mouse pre-implantation embryonic development

Junqiang Zhang, Juanjuan Zhang, Chun Zhao, Rong Shen, Xirong Guo, Chaojun Li, Xiufeng Ling, Chang Liu
Pages: 535-540
Published online on: 25 November 2013

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Article

microRNA‑202 suppresses MYCN expression under the control of E2F1 in the neuroblastoma cell line LAN‑5

Yu‑Guang Li, Jin‑Hua He, Liu Yu, Ze‑Ping Hang, Wang Li, Wen‑Hong Shun, Guo Xian Huang
Pages: 541-546
Published online on: 06 December 2013

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Article

Gene expression profiling of lens tumors, liver and spleen in α-crystallin/SV40 T antigen transgenic mice treated with Juzen-taiho-to

Hua-Chuan Zheng, Akira Noguchi, Keiji Kikuchi, Toshihiko Ando, Takafumi Nakamura, Yasuo Takano
Pages: 547-552
Published online on: 10 December 2013

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Article

Heat shock‑mediated regulation of IκB‑α at the post‑transcriptional level by HuR

Yuxin Liu, Wenyan Yu
Pages: 553-559
Published online on: 20 November 2013

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Article

High‑dose fasudil preconditioning and postconditioning attenuate myocardial ischemia‑reperfusion injury in hypercholesterolemic rats

Nan Wu, Xiaowen Zhang, Dalin Jia
Pages: 560-566
Published online on: 20 November 2013

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Article

Schwann cells differentiated from adipose‑derived stem cells for the treatment of brain contusion

Liang Yang, Jiasheng Fang, Daguang Liao, Wei Wang
Pages: 567-573
Published online on: 25 November 2013

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Article

Co‑culture of human nucleus pulposus cells with multipotent mesenchymal stromal cells from human bone marrow reveals formation of tunnelling nanotubes

Tomasz P. Lehmann, Krystyna Filipiak, Wojciech  Juzwa, Patrycja  Sujka‑Kordowska, Paweł P. Jagodziński, Maciej Zabel, Jakub  Głowacki, Ewa  Misterska, Michał Walczak, Maciej Głowacki
Pages: 574-582
Published online on: 21 November 2013

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Article

Function of inducible nitric oxide synthase in the regulation of cervical cancer cell proliferation and the expression of vascular endothelial growth factor

Jing Dong, Mingjun Cheng, Hong Sun
Pages: 583-589
Published online on: 02 December 2013

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Article

Regulation of the levels of Smad1 and Smad5 in MC3T3-E1 cells by Icariine in vitro

Huifang Zhou, Shuo Wang, Yuan Xue, Nianke Shi
Pages: 590-594
Published online on: 02 December 2013

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Article

Substance P attenuates hyperoxia‑induced lung injury in neonatal rats

Lin Yang, Cong Liu, Hongxing Dang, Fang Fang, Lingping Tan, Ping Zhao, Feng Xu, Chenjun Liu
Pages: 595-599
Published online on: 18 November 2013

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Article

Survivin gene expression increases gastric cancer cell lymphatic metastasis by upregulating vascular endothelial growth factor-C expression levels

Junyan Zhang, Zhi Zhu, Zhe Sun, Xuren Sun, Zhenning Wang, Huimian Xu
Pages: 600-606
Published online on: 11 December 2013

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Article

Development of a canine model with diffuse hepatic vein obstruction (Budd‑Chiari syndrome) via endovascular occlusion

Bin Shen, Qingqiao Zhang, Xiaolong Wang, Hao Xu, Maoheng Zu, Meng Wu, Zhikang Gao, Wenliang Wang, Jinchang Xiao, Yong Wang
Pages: 607-613
Published online on: 17 December 2013

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Article

Clinical significance of Smac and survivin expression in breast cancer patients treated with anthracycline‑based neoadjuvant chemotherapy

Ying-Chun Zhao, Yan Wang, Xiao-Jian Ni, Yong Li, Xiu‑Ming Wang, Yong-Yun Zhu, Chuan-Yu Luo
Pages: 614-620
Published online on: 04 December 2013

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Article

Integration of microarray profiles associated with cardiomyopathy and the potential role of Ube3a in apoptosis

Jie Zhang, Rui Song, Yanfei Li, Jian Feng, Luying Peng, Jue Li
Pages: 621-625
Published online on: 09 December 2013

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Article

Optimization of 2-dimensional gel electrophoresis for proteomic studies of solid tumor tissue samples

Xu Liang, Jing-Rong Wang, Kam-Wai V. Wong, Wen Luan Hsiao, Hua Zhou, Zhi-Hong Jiang, Kin Ting R. Kam, Liang Liu
Pages: 626-632
Published online on: 20 November 2013

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Article

β-catenin mediates the inflammatory cytokine expression induced by the Der p 1 house dust mite allergen

Jaewoong Jang, Jong-Hyeok Ha, Seok-Min Kim, Wonyong Kim, Kijeong Kim, Sang-In Chung, Yoosik Yoon
Pages: 633-638
Published online on: 10 December 2013

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Article Open Access

Effects of recombinant human interleukin‑10 on Treg cells, IL‑10 and TGF‑β in transplantation of rabbit skin

Kai Shan Liu, Xiao Qin Fan, Lei Zhang, Qiong Na Wen, Ji  Hong Feng, Fu Chao Chen, Jun Min Luo, Wan Bang Sun
Pages: 639-644
Published online on: 20 November 2013

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Article

Influence of cytotoxic T lymphocyte-associated antigen 4 polymorphisms on the outcomes of hepatitis B virus infection

Man Chen, Ying Chang, Feng Tang, Qiong-Hui Xie, Jin Li, Hong Yang, Xing-Xing  He, Ju-Sheng Lin
Pages: 645-652
Published online on: 22 November 2013

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Article

Immunogenic response induced by wzm and wzt gene deletion mutants from Brucella abortus S19

Xiu-Ran Wang, Guang-Mou Yan, Rui Zhang, Xu-Long Lang, Yan‑Ling Yang, Xiao-Yan Li, Si Chen, Jing Qian, Xing-Long Wang
Pages: 653-658
Published online on: 18 November 2013

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Article

Effects of the combination of dexamethasone and fibroblast growth factor‑2 on differentiation of osteoprecursor cells

Jun‑Beom Park
Pages: 659-662
Published online on: 19 November 2013

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Article

Extracellular signal‑regulated kinase inhibition is required for methanol extract of Smilax china L.‑induced apoptosis through death receptor 5 in human oral mucoepidermoid carcinoma cells

Hyun‑Ju Yu, Ji‑Ae Shin, Syng‑Ook Lee, Ki Han Kwon, Sung‑Dae Cho
Pages: 663-668
Published online on: 22 November 2013

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Article

Cinnamaldehyde/chemotherapeutic agents interaction and drug-metabolizing genes in colorectal cancer

Chen Yu, Shen-Lin Liu, Ming-Hao Qi, Xi Zou
Pages: 669-676
Published online on: 26 November 2013

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Article

Improvement of intestinal microflora balance by polysaccharide from Physalis alkekengi var. francheti

Xinli Li, Guang Yang, Cuili Zhang, Dachang Wu, Li Tang, Yi Xin
Pages: 677-682
Published online on: 02 December 2013

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Article

Selenium‑enriched exopolysaccharides produced by Enterobacter cloacae Z0206 alleviate adipose inflammation in diabetic KKAy mice through the AMPK/SirT1 pathway

Xihong Zhou, Fengqin Wang, Hangxian Yang, Jingqing Chen, Yang Ren, Zhangqin Yuan, Xinxia Wang, Yizhen Wang
Pages: 683-688
Published online on: 11 December 2013

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Article

Suppression of 2,4-dinitrochlorobenzene-induced atopic dermatitis by extract of Bacillus Calmette-Guerin

Mingli Sun, Shuang Wang, Lin Zhao, Haishan Zhao, Weifan Yao, Wanbao Jin, Minjie Wei
Pages: 689-694
Published online on: 16 December 2013

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Article

Influence of genes and the environment in familial congenital heart defects

Xike Wang, Pingjuan Li, Sun Chen, Lili Xi, Ying Guo, Aihua Guo, Kun Sun
Pages: 695-700
Published online on: 06 December 2013

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Article

Chloroform fraction of Scutellaria barbata D. Don promotes apoptosis and suppresses proliferation in human colon cancer cells

Ling Zhang, Qiaoyan Cai, Jiumao Lin, Yi Fang, Youzhi Zhan, Aling Shen, Lihui Wei, Lili Wang, Jun Peng
Pages: 701-706
Published online on: 16 December 2013

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Article

Suppression of collagen synthesis by Dicer gene silencing in hepatic stellate cells

Fujun Yu, Zhuo Lin, Jianjian Zheng, Shenmeng Gao, Zhongqiu Lu, Peihong Dong
Pages: 707-714
Published online on: 16 December 2013

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Article

Expression, purification and characterization of human interferon-γ in Pichia pastoris

Dan Wang, Hui Ren, Jing-Wei Xu, Peng-Da Sun, Xue-Dong Fang
Pages: 715-719
Published online on: 19 November 2013

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Article

Identification of paired immunoglobulin‑like type 2 receptor α as hepatitis B virus DNA polymerase transactivated protein 1 interacting proteins

Yong‑Zhi Lun, Qing Chi, Xue‑Lei Wang, Fang Wang, Wen Sui
Pages: 720-724
Published online on: 19 November 2013

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Article

Detection of DNA hypermethylation in sera of patients with Crohn's disease

Jin-Han Bae, Jongha Park, Kwang Mo Yang, Tae-Oh Kim, Joo Mi Yi
Pages: 725-729
Published online on: 03 December 2013

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Article

Hepatitis C virus alternate reading frame protein decreases interferon‑α secretion in peripheral blood mononuclear cells

Xiaodong Xu, Xiaojie Yu, Xiaozhao Deng, Ming Yue, Jinhai Zhang, Danyan Zhu, Zhenxian Zhou, Xiangjun Zhai, Ke Xu, Yun Zhang
Pages: 730-736
Published online on: 20 November 2013

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Article

Association analysis of IL7R polymorphisms with inflammatory demyelinating diseases

Jason Yongha Kim, Hyun Sub Cheong, Ho Jin Kim, Lyoung Hyo Kim, Suhg Namgoong, Hyoung Doo Shin
Pages: 737-743
Published online on: 13 December 2013

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Article

The extract of Elaeocarpus sylvestris inhibits human cytomegalovirus immediate early gene expression and replication in vitro

Kim Phuong To, Se Chan Kang, Yoon-Jae Song
Pages: 744-748
Published online on: 22 November 2013

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Article

Mutational analysis of the BRCA2 gene in breast carcinoma patients of Kashmiri descent

Shiekh Gazalla Ayub, Shabhat Rasool, Taha Ayub, Saquib Naveed Khan, Khursheed Alam Wani, Khurshid Iqbal Andrabi
Pages: 749-753
Published online on: 13 December 2013

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Article

Carbon monoxide releasing molecule‑2 attenuated ischemia/reperfusion‑induced apoptosis in cardiomyocytes via a mitochondrial pathway

Shen Zhao, Qingming Lin, Heng Li, Yumin He, Xiangshao Fang, Feng Chen, Changwei Chen, Zitong Huang
Pages: 754-762
Published online on: 13 December 2013

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Article

Butein induces cell apoptosis and inhibition of cyclooxygenase‑2 expression in A549 lung cancer cells Corrigendum in /10.3892/mmr.2020.11616

Yang Li, Chengyuan Ma, Ming Qian, Zhongmei Wen, Hongyu Jing, Donghua Qian
Pages: 763-767
Published online on: 09 December 2013

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Article

Antitumor activity of celecoxib, a selective cyclooxygenase-2 inhibitor, in medullary thyroid carcinoma

Qiang Zhang, Xianying Meng, Guibin Zheng, Guang  Chen, Renzhu Pang, Tebo Hua, Shuai Yang
Pages: 768-772
Published online on: 17 December 2013

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Journal Cover
January-2026 Volume 33 Issue 1

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

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Non‑coding RNAs in epithelial‑mesenchymal transition of renal cell carcinoma (Review)

Ziqiao Liu, Hanshen Zhou, Junxiao Shen, Yiming Qi, Xuke Gong, Cheng Zhang
Article Number: 51
Published online on: 24 November 2025

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FOXJ3 drives mesenchymal stem cell osteogenic differentiation via the Wnt/β‑catenin pathway: A novel regulator implicated in osteoporosis

Hongwei Xiao, Jianfeng Li, Wei Huang, Yi Qin
Article Number: 50
Published online on: 21 November 2025

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NEDD4 regulates VEGF signaling and mTOR to promote angiogenesis and the cell cycle in steroid‑induced osteonecrosis of the femoral head

Jian Li, Dong Zhen, Yuhuan Qin, Caifen Guo
Article Number: 49
Published online on: 21 November 2025

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Glabridin attenuates LTA‑induced alveolar macrophage migration via activation of the Nrf2/HO‑1 pathway

Chih-Hsuan Hsia, Chun-Ming Yang, Chao-Chien Chang, Ting-Lin Yen, Arief Gunawan Darmanto, Chi-Chang Huang, Joen-Rong Sheu
Article Number: 48
Published online on: 21 November 2025

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Research progress on molecular therapy for glaucoma (Review)

Weiwei Wang, Gangwei Cheng, Qi Zhou, Sheng Wang, Linyi Zhang
Article Number: 47
Published online on: 21 November 2025

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Natural compounds for the treatment of rheumatoid arthritis based on the ‘gut‑joint axis’ (Review)

Wenjie Hu, Rui Li, Zhongming Zhang
Article Number: 46
Published online on: 20 November 2025

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TGM1 as a novel signature gene in psoriasis identified by integrative bioinformatics and experimental validation

Pan Guo, Mengke Sun, Jingyu Zhang, Qianshu Yuan, Hong Cui, Junkai Huang, Jing Luo, Qianyu Zhu, Bingxin Zhang, Lizhi Hu
Article Number: 45
Published online on: 20 November 2025

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CDK1‑induced regulation of p53 phosphorylation at Ser315 mediates cell cycle arrest and apoptosis of macrophages infected with clinical isolates of Mycobacterium tuberculosis

Banghao Sun, Zhenyu Zhao, Qingyu Meng, Luya Pu, Xingyu Jiang, Shuai Li, Fadi Cao, Fan Li
Article Number: 44
Published online on: 20 November 2025

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High‑intensity exercise training inhibits excessive autophagy in the hyperlipidemic myocardium of ApoE‑/‑ mice via the NAD+‑mediated SIRT1/MFN2 pathway

Shan Gao, Wei Yao, Jin Yang, Yujie Liu, Zuowei Pei
Article Number: 43
Published online on: 18 November 2025

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[Corrigendum] Protective effects of metformin against myocardial ischemia‑reperfusion injury via AMPK‑dependent suppression of NOX4

Yan Shi, Shu-Ai Hou
Article Number: 42
Published online on: 17 November 2025

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Apelin promotes RANKL‑mediated osteoclastogenesis by activating MAPK and NF‑κB pathways

Yu-Han Wang, Yu-Ying Wu, Chun-Hao Tsai, Yi-Chin Fong, Chih-Yuan Ko, Hsien-Te Chen, Yat-Yin Law, Chih-Hsin Tang
Article Number: 41
Published online on: 12 November 2025

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Identification of multimorbidity hub genes for knee osteoarthritis-atherosclerosis and potential clinical applications

Qingyuan Kang, Ping Yuan, Peisen Xie, Wentao Xiao, Liguang Dong, Zhenpeng Guan, Keshi Zhang
Article Number: 40
Published online on: 12 November 2025

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CTSB mediates oxidative stress and intestinal epithelial barrier disruption in intestinal ischemia‑reperfusion injury

Shuang He, Lei Wang, Zhe Wang, Shiyong Yu, Qi Zhu, Yijun Xu, Yuhang Jiang, Yingxia Wu, Honggang Xiang
Article Number: 39
Published online on: 12 November 2025

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Astragaloside IV promotes the apoptosis of pancreatic cancer cells by activating endoplasmic reticulum stress through the PERK/ATF4/CHOP signaling pathway

Yijun Wang, Mengyang Zhao, Shanshan Liu, Rui Zheng, Tianhui Gao
Article Number: 38
Published online on: 11 November 2025

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[Retracted] Baicalin inhibits influenza virus A replication via activation of type I IFN signaling by reducing miR‑146a

Rui Li, Lianxin Wang
Article Number: 37
Published online on: 10 November 2025

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Migrasomes: Emerging players in intercellular communication and disease pathogenesis (Review)

Yuanliang Cao, Quan Wan, Boqi Zhou, Haixin Zeng, Xiaojie Lu
Article Number: 36
Published online on: 10 November 2025

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Diabetic keratopathy and nuclear proteins (Review)

Haiying Xu, Zhi-Liang Jiang, Yuehong Wang, Xiaoli Hou, Weixia Dong, Yanfang Chen, Qiuying Zhang, Xinying Ji, Shaoping Ji, Yalong Dang
Article Number: 35
Published online on: 10 November 2025

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Homocystinuria: Advances in metabolic and molecular therapies targeting homocysteine pathways (Review)

Ayman A. Althubity
Article Number: 34
Published online on: 10 November 2025

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Synovial chondromatosis: Novel advances in understanding the pathogenesis and in diagnostic strategies (Review)

Xingzheng Deng, Shizhang Liu, Huitong Liu
Article Number: 33
Published online on: 10 November 2025

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Protective effects of Notoginsenoside R1 on the ferroptosis of a human non‑small cell lung cancer cell line

Yuejiao Zhang, Zhongshun Mao, Yong Diao
Article Number: 32
Published online on: 06 November 2025

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Unraveling the synergy of inflammation and apoptosis in sepsis-induced acute lung injury: Insights and therapeutic perspectives (Review)

Liwen Zhang, Haoxuan Li, Dongxu Li, Qingqing Dai
Article Number: 31
Published online on: 03 November 2025

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Dihydroalterperylenol from endophytic fungus Alternaria semiverrucosa and its antitumour activity uncovered by transcriptome analysis, molecular docking and molecular dynamics simulations

Mingfei Yang, Yongzhong Lu, Long Han, Zhangjiang He, Jichuan Kang
Article Number: 30
Published online on: 03 November 2025

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[Retracted] Phosphoinositide 3‑kinase/Akt pathway is involved in pingyangmycin‑induced growth inhibition, apoptosis and reduction of invasive potential in EOMA mouse hemangioendothelioma cells

Li-Xia Peng, Ping Zhao, Hong-Sheng Zhao, Er Pan, Bin-Bin Yang, Qin Li
Article Number: 29
Published online on: 03 November 2025

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Tight junction dysfunction and cytoskeletal remodeling in Hirschsprung‑associated enterocolitis: A decade of mechanistic insights and therapeutic prospects (Review)

Shuai Li, Chen Wang, Ling Zhang, Shan Chen, Ying Zhou, Dehua Yang, Kang Li, Yuan Liu, Shuiqing Chi, Yong Wang, Lizhi Li, Shao-Tao Tang
Article Number: 28
Published online on: 03 November 2025

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Involvement of the thioredoxin system in multiple diseases: A focus on mechanisms of action in autophagy and ferroptosis (Review)

Weihua Wang, Yingdong Mou, Dunlin Lu, Shanshan Xu
Article Number: 27
Published online on: 03 November 2025

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MicroRNA‑199a‑3p suppresses non‑small cell lung cancer progression by targeting FTO to enhance m6A‑mediated downregulation of MZF1 and its transcriptional activation of CLDND1

Yuzhen Cui, Xiaoqian Li, Hongkui Zhang, Weiqiang Yuan, Enbo Zhu
Article Number: 26
Published online on: 03 November 2025

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Role of ubiquitin‑proteasome system in preeclampsia (Review)

Chang-Zhu Pei, Xiao-Xing Song, Hao Xu, Kwang-Hyun Baek
Article Number: 25
Published online on: 03 November 2025

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Schisantherin A induces ferroptosis in non‑small cell lung cancer through activation of the YAP/ACSL4/TfR signaling pathway

Wenxiang Zhu, Yeyang Chen, Xiangjian Wu, Xiaoyan Fu, Yongshi He, Yuxia Mo, Qinghua Zhu, Mingwen Tang, Zhiguang Zhai
Article Number: 24
Published online on: 03 November 2025

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The gut‑bone‑cartilage triad: Microbial regulation of the Wnt/β‑catenin signaling pathway in osteoarthritis joint remodeling (Review)

Ruipu Zhang, Liang Zhang, Bin Tian, Yiqun Wang, Xin Kang, Jiang Zheng
Article Number: 23
Published online on: 31 October 2025

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Protective impact of landiolol against acute lung injury following hemorrhagic shock and resuscitation in rats

Risa Sakamoto, Hiroko Shimizu, Ryu Nakamura, Yifu Lu, Yaqiang Li, Emiko Omori, Toru Takahashi, Hiroshi Morimatsu
Article Number: 22
Published online on: 31 October 2025

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Hidden connection: Impact of the gut microbiota on respiratory diseases in children (Review)

Yanhua Han, Yuchao Jia, Lili Chen, Mingyao Zhang
Article Number: 21
Published online on: 29 October 2025

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From renal development to pathology: An analysis of the multilevel role of insulin‑like growth factor 2 (Review)

Yuping Sun, Wenke Hao, Wei Liu, Wenxue Hu
Article Number: 20
Published online on: 29 October 2025

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[Corrigendum] Early anticoagulation therapy for severe burns complicated by inhalation injury in a rabbit model

Zhong-Hua Fu, Guang-Hua Guo, Zhen-Fang Xiong, Xincheng Liao, Ming-Zhuo Liu, Jinhua Luo
Article Number: 19
Published online on: 29 October 2025

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Mucin 2 and unfolded protein response reshape the mucus barrier in inflammatory bowel disease (Review)

Zhiwei Yuan, Zheng Xia, Liyun Ling, Jingzhe Xie, Feng Zhang
Article Number: 18
Published online on: 29 October 2025

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RING finger protein family in leukemia (Review)

Ye Wang, Yue Zhao, Jihong Zhang
Article Number: 17
Published online on: 29 October 2025

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Retinal light perception and biological rhythms: The role of light in sleep and mood from an ophthalmic perspective (Review)

Man Yuan, Hanxiang Liu, Ranjie Zhu, Yuzhen Li, Siyuan Song, Anhuai Yang
Article Number: 16
Published online on: 29 October 2025

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Retraction Open Access

[Retracted] Oxymatrine‑mediated maturation of dendritic cells leads to activation of FOXP3+/CD4+ Treg cells and reversal of cisplatin‑resistance in lung cancer cells

Hui Liu, Manman Zou, Pei Li, Haifeng Wang, Xijun Lin, Jin Ye
Article Number: 15
Published online on: 27 October 2025

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Zinc finger protein 514 promotes esophageal cancer progression by enhancing cell proliferation, migration and invasion

Lin Lv, Xiaoming Sun, Houlu Zhang, Guangxu Wang, Chao Zhang, Haibo Liu, Liangming Zhu
Article Number: 14
Published online on: 24 October 2025

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Effects of zinc carnosine on bone loss in mice with diabetic osteoporosis 

Jingyuan Gao, Hao Yang, Qiangqiang Lian, Yunpeng Hu, Zhou Yang, Lei Xing, Ying Xue, Xiaoli Hou, Faming Tian, Dong Hu
Article Number: 13
Published online on: 24 October 2025

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Rapamycin improves endometriosis‑related infertility involving ovarian senescence via the PPARα/IGFBP2 pathway

Qiongwei Wu, Jiao Fan, Qingjing Sheng, Xiaoying He
Article Number: 12
Published online on: 24 October 2025

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Combining tadalafil and hyperbaric oxygen therapy protects against ovarian ischemia‑reperfusion damage in rats

Mehmet Akif Baktir, Mustafa Ermis, Esra Balcioglu, Betul Yalcin, Enes Karaman, Ahmet Cumaoglu
Article Number: 11
Published online on: 23 October 2025

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Liquid‑liquid phase separation of PHLDB2 promotes oral squamous cell carcinoma metastasis through regulating epithelial mesenchymal transition and PIK3CA expression

Kunyi Chen, Yuhong Wang, Jianing Cui, Qianrui Liu, Xiaoyong Liu, Wenjin Wang, Jinsong Hou
Article Number: 10
Published online on: 22 October 2025

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Article

Mitochondrial gatekeeper in hepatocellular carcinoma: Unraveling the multifaceted roles of VDAC in metabolic reprogramming, apoptosis evasion and therapeutic innovation (Review)

Jie Wang, Yu Liang, Xiaotao Jia, Xinmao Yang, Danning Shi, Yuanchun Wang, Yanfang Pan
Article Number: 9
Published online on: 21 October 2025

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Retraction Open Access

[Retracted] Knockdown of ubiquitin‑specific protease 51 attenuates cisplatin resistance in lung cancer through ubiquitination of zinc‑finger E‑box binding homeobox 1

Feng Zhou, Chunling Du, Donghui Xu, Jinchang Lu, Lei Zhou, Chaomin Wu, Bo Wu, Jianan Huang
Article Number: 8
Published online on: 20 October 2025

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Exploring the role of cytochrome P450 family 1 subfamily B member 1 and quercetin in modulating neuropathic pain after spinal cord injury

Pengyu Zhou, Lu Li, Yu Cao, Jiahao Chen, Chuyin Chen, Xiangsheng Zhang, Jiurong Chen, Yingdong Deng, Ziqiang Lin, Yupei Lai, Suo Wang, Simin Tang, Wenqi Zhang, Peng Sun, Jun Zhou
Article Number: 7
Published online on: 15 October 2025

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R‑loops in hepatocellular carcinoma: Bridging genomic instability and therapeutic opportunity (Review)

Ching-Hua Hsieh, Yueh-Wei Liu, Pei-Chin Chuang
Article Number: 6
Published online on: 15 October 2025

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Role and relevance of exosome-mediated epigenetic regulation in the pathogenesis, diagnosis and treatment of 
cardiovascular diseases (Review)

Yishuo Zhang, Shanshan Zhang, Yijing Li, Wenqi Jin, Liya Zhou, Jing Lu
Article Number: 5
Published online on: 15 October 2025

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PLIN5 deficiency ameliorates metabolic dysfunction‑associated fatty liver disease by inhibiting ferroptosis

Ya Li, Xiaohan Wang, Xuecui Yin, Xiaohui Zhu, Weiqi Cui, Lin Dong, Yu Xia, Ying Wang, Liu Liu, Pengyuan Zheng, Youcai Tang
Article Number: 4
Published online on: 14 October 2025

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Circadian clock genes: Their influence on liver metabolism, disease development and treatment (Review)

Junmin Wang, Mengxing Cao, Shen Li, Wen Pei, Jing Li, Zhen Wang
Article Number: 3
Published online on: 14 October 2025

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MALT1 inhibition by MI‑2 suppresses epithelial‑to‑mesenchymal transition and fibrosis by inactivating the NF‑κB pathway in high glucose‑treated HK‑2 cells

Yating Lan, Jian Ma, Huijun Chen, Chaohong Lan, Na Zhao
Article Number: 2
Published online on: 14 October 2025

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[Retracted] Protective effect of erythropoietin against myocardial injury in rats with sepsis and its underlying mechanisms

Xinliang Zhang, Shimin Dong, Yanjun Qin, Xiaohua Bian
Article Number: 1
Published online on: 14 October 2025

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February-2026 Volume 33 Issue 2

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Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Mitophagy and oxidative stress in chronic kidney disease (Review)

Quwu Mushuo, Yihuai Tian, Jianchun Li, Yanqin Qiu, Hui Fan, Qiongdan Hu, Qiong Zhang
Article Number: 61
Published online on: 04 December 2025

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ABCC9 knockdown attenuates isoproterenol‑induced myocardial hypertrophy by inhibiting the PI3K/AKT signaling pathway

Qian Peng, Rui Chang, Linlin Ma, Yanfei Li
Article Number: 60
Published online on: 04 December 2025

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MeCP2 suppresses ferroptosis to drive EMT in retinal pigment epithelial cells: Implications for PVR pathogenesis

Sibei Guo, Yongya Zhang, Xue Li, Xueru Zhao, Yingjuan Liang, Xiaohua Li
Article Number: 59
Published online on: 04 December 2025

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[Corrigendum] Screening for implicated genes in colorectal cancer using whole‑genome gene expression profiling

Long-Ci Sun, Hai-Xin Qian
Article Number: 58
Published online on: 04 December 2025

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Hyperoside prevents osteoporosis by activating the PI3K/AKT signaling pathway to inhibit oxidative stress and promote osteogenesis

Lirong Li, Huaidong Deng, Shabin Zhuan, Boyu Wu, Dawei Xiao
Article Number: 57
Published online on: 03 December 2025

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[Retracted] Interference with Tim‑3 protein expression attenuates the invasion of clear cell renal cell carcinoma and aggravates anoikis

Muming Yu, Bin Lu, Yancun Liu, Ying Me, Lijun Wang, Hui Li
Article Number: 56
Published online on: 01 December 2025

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Acetylshikonin induces ferroptosis via the lipid peroxidation pathway in osteosarcoma cells

Ji-Ying Chen, Guo-Shou Wang, Tsung-Ming Chang, Ju-Fang Liu
Article Number: 55
Published online on: 27 November 2025

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Liver X receptor: A potential target for inflammatory bowel disease and colorectal cancer (Review)

Yingjie Li, Xiaoyan Fu, Meiwen Bai, Jiaqi Zhou, Jiatai Qiu, Hongxia Zhang, Shujuan Liang, Meifang Liu
Article Number: 54
Published online on: 27 November 2025

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lncRNA NEAT1 promotes the proliferation of hemangioma cells by transcriptionally activating β‑catenin via enhancing H3K18 lactylation

Li Yu, Nian Zhou, Xiao-Liang Zhang, Xue-Jing Pang, Lu Xing, Yun-Jing Pu, Li Zhang, Jing-Nan Wu, Hong Shu
Article Number: 53
Published online on: 25 November 2025

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[Retracted] MicroRNA‑206 exerts anti‑oncogenic functions in esophageal squamous cell carcinoma by suppressing the c‑Met/AKT/mTOR pathway

Jin Zhang, Xianen Fa, Qingyong Zhang
Article Number: 52
Published online on: 25 November 2025

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