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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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International Journal of Molecular Medicine

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
June-2015 Volume 35 Issue 6

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Journal Metrics

Impact Factor: 8.5

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

The utility of mouse models to provide information regarding the pathomolecular mechanisms in human genetic skeletal diseases: The emerging role of endoplasmic reticulum stress (Review)

Michael D. Briggs, Peter A. Bell, Katarzyna A. Pirog
Pages: 1483-1492
Published online on: 30 March 2015

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Review

Retinoic acid-related orphan receptor RORβ, circadian rhythm abnormalities and tumorigenesis (Review)

Shujiong Feng, Song Xu, Zhenzhen Wen, Yongliang Zhu
Pages: 1493-1500
Published online on: 26 March 2015

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Article Open Access

Elevated survivin expression in peripheral blood mononuclear cells is central to collateral formation in coronary chronic total occlusion

Yiguan Xu, Xuerui Tan, Dongming Wang, Wei Wang, Yuguang Li, Min Wu, Songming Chen, Yinge Wu, Chunjiang Tan
Pages: 1501-1510
Published online on: 24 March 2015

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Article Open Access

Maternal peripheral blood natural killer cells incorporate placenta-associated microRNAs during pregnancy

Yoichi Ishida, Dongwei Zhao, Akihide Ohkuchi, Tomoyuki Kuwata, Hiroshi Yoshitake, Kazuya Yuge, Takami Takizawa, Shigeki Matsubara, Mitsuaki Suzuki, Shigeru Saito, Toshihiro Takizawa
Pages: 1511-1524
Published online on: 27 March 2015

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Article Open Access

Silencing of uncoupling protein 2 by small interfering RNA aggravates mitochondrial dysfunction in cardiomyocytes under septic conditions

Guilang Zheng, Juanjuan Lyu, Shu Liu, Jinda Huang, Cui Liu, Dan Xiang, Meiyan Xie, Qiyi Zeng
Pages: 1525-1536
Published online on: 09 April 2015

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Article Open Access

Ischemic preconditioning protects neurons from damage and maintains the immunoreactivity of kynurenic acid in the gerbil hippocampal CA1 region following transient cerebral ischemia

Jae-Chul Lee, Hyun-Jin Tae, Geum-Sil Cho, In Hye Kim, Ji Hyeon Ahn, Joon Ha Park, Bai Hui Chen, Jeong-Hwi Cho, Bich Na Shin, Jun Hwi Cho, Eun Joo Bae, Jinseu Park, Young-Myeong Kim, Soo Young Choi, Moo-Ho Won
Pages: 1537-1544
Published online on: 07 April 2015

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Article Open Access

GATA4 transgenic mice as an in vivo model of congenital heart disease

Hua Han, Yu Chen, Gang Liu, Zengqiang Han, Zhou Zhao, Yin Tang
Pages: 1545-1553
Published online on: 09 April 2015

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Article Open Access

Application of multiplex ligation-dependent probe amplification, and identification of a heterozygous Alu-associated deletion and a uniparental disomy of chromosome 1 in two patients with 3-hydroxy-3-methylglutaryl-CoA lyase deficiency

Yuka Aoyama, Toshiyuki Yamamoto, Naomi Sakaguchi, Mika Ishige, Toju Tanaka, Tomoko Ichihara, Katsuaki Ohara, Hiroko Kouzan, Yasutomi Kinosada, Toshiyuki Fukao
Pages: 1554-1560
Published online on: 14 April 2015

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Article Open Access

Activating transcription factor 3 is overexpressed in human glioma and its knockdown in glioblastoma cells causes growth inhibition both in vitro and in vivo

Siqi Ma, Changhe Pang, Laijun Song, Fuyou Guo, Hongwei Sun
Pages: 1561-1573
Published online on: 07 April 2015

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Article Open Access

Changes in Dpysl2 expression are associated with prenatally stressed rat offspring and susceptibility to schizophrenia in humans

Hwayoung Lee, Jaesoon Joo, Seong-Su Nah, Jong Woo Kim, Hyung-Ki Kim, Jun-Tack Kwon, Hwa-Young Lee, Young Ock Kim, Hak-Jae Kim
Pages: 1574-1586
Published online on: 01 April 2015

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Article Open Access

miR‑204-5p promotes the adipogenic differentiation of human adipose-derived mesenchymal stem cells by modulating DVL3 expression and suppressing Wnt/β-catenin signaling

Honghui He, Ke Chen, Fang Wang, Liling Zhao, Xinxing Wan, Linghao Wang, Zhaohui Mo
Pages: 1587-1595
Published online on: 31 March 2015

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Article Open Access

Epigenetic repression of Krüppel-like factor 4 through Dnmt1 contributes to EMT in renal fibrosis

Xiangcheng Xiao, Wenbin Tang, Qiongjing Yuan, Ling Peng, Pingping Yu
Pages: 1596-1602
Published online on: 20 April 2015

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Article

Human neutrophil peptides induce interleukin-8 in intestinal epithelial cells through the P2 receptor and ERK1/2 signaling pathways

Kazunari Ibusuki, Toshio Sakiyama, Shuji Kanmura, Takuro Maeda, Yuji Iwashita, Yuichiro Nasu, Fumisato Sasaki, Hiroki Taguchi, Shinichi Hashimoto, Masatsugu Numata, Hirofumi Uto, Hirohito Tsubouchi, Akio Ido
Pages: 1603-1609
Published online on: 26 March 2015

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Article

Curcumin induces the apoptosis of non-small cell lung cancer cells through a calcium signaling pathway

Xudong Xu, Da Chen, Bo Ye, Fangming Zhong, Gang Chen
Pages: 1610-1616
Published online on: 02 April 2015

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Article

Combination of 12-O-tetradecanoylphorbol-13-acetate with diethyldithiocarbamate markedly inhibits pancreatic cancer cell growth in 3D culture and in immunodeficient mice

Huarong Huang, Kajia Cao, Saquib Malik, Qiuyan Zhang, Dongli Li, Richard Chang, Huaqian Wang, Weiping Lin, Jeremiah Van Doren, Kun Zhang, Zhiyun Du, Xi Zheng
Pages: 1617-1624
Published online on: 01 April 2015

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Article

Ischemic preconditioning increases GSK-3β/β-catenin levels and ameliorates liver ischemia/reperfusion injury in rats

Yichao Yan, Guangying Li, Xiaofeng Tian, Yingjiang Ye, Zhidong Gao, Jihong Yao, Feng Zhang, Shan Wang
Pages: 1625-1632
Published online on: 23 March 2015

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Article

NLRP3 inflammasome is responsible for Hantavirus inducing interleukin-1β in THP-1 cells Corrigendum in /10.3892/ijmm.2019.4155

Wei Ye, Yingfeng Lei, Mengmeng Yu, Yongni Xu, Mengyuan Cao, Lan Yu, Liang Zhang, Puyuan Li, Wentao Bai, Zhikai Xu, Fanglin Zhang
Pages: 1633-1640
Published online on: 01 April 2015

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Article

Hedgehog signaling is involved in the BMP9-induced osteogenic differentiation of mesenchymal stem cells Retraction in /10.3892/ijmm.2023.5233

Li Li, Qian Dong, Yufeng Wang, Qiaoling Feng, Pengfei Zhou, Xinying Ou, Qiurong Meng, Tongchuan He, Jinyong Luo
Pages: 1641-1650
Published online on: 07 April 2015

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Article

Effects of bee venom against Propionibacterium acnes‑induced inflammation in human keratinocytes and monocytes

Jung-Yeon Kim, Woo-Ram Lee, Kyung-Hyun Kim, Hyun-Jin An, Young-Chae Chang, Sang-Mi Han, Yoon-Yub Park, Sok Cheon Pak, Kwan-Kyu Park
Pages: 1651-1656
Published online on: 09 April 2015

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Article

Hydrogen sulfide attenuates IL-1β-induced inflammatory signaling and dysfunction of osteoarthritic chondrocytes

Chengzhi Ha, Shaoqi Tian, Kang Sun, Dawei Wang, Jiangtao Lv, Yuanhe Wang
Pages: 1657-1666
Published online on: 14 April 2015

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Article

AST Ⅳ inhibits H2O2-induced human umbilical vein endothelial cell apoptosis by suppressing Nox4 expression through the TGF-β1/Smad2 pathway

Yuhong Ma, Weizu Li, Yanyan Yin, Weiping Li
Pages: 1667-1674
Published online on: 17 April 2015

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Article

MAGE-A expression clusters and antineoplastic treatment in head and neck cancer

Stefan Hartmann, Till J. Meyer, Roman C. Brands, Imme R. Haubitz, Christian Linz, Axel Seher, Alexander C. Kübler, Urs D.A. Müller-Richter
Pages: 1675-1682
Published online on: 07 April 2015

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Article

LSm1 binds to the Dengue virus RNA 3' UTR and is a positive regulator of Dengue virus replication

Yangchao Dong, Jing Yang, Wei Ye, Yuan Wang, Yunbo Miao, Tianbing Ding, Chen Xiang, Yingfeng Lei, Zhikai Xu
Pages: 1683-1689
Published online on: 07 April 2015

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Article

Anti-inflammatory potential of saponins derived from cultured wild ginseng roots in lipopolysaccharide-stimulated RAW 264.7 macrophages

Gyeong-Jin Yu, Il-Whan Choi, Gi-Young Kim, Byung-Woo Kim, Cheol Park, Su-Hyun Hong, Sung-Kwon Moon, Hee-Jae Cha, Young-Chae Chang, Kee Yoeup Paek, Wun-Jae Kim, Yung Hyun Choi
Pages: 1690-1698
Published online on: 02 April 2015

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Article

Protective effects of Semen Crotonis Pulveratum on trinitrobenzene sulphonic acid-induced colitis in rats and H2O2-induced intestinal cell apoptosis in vitro

Xiaohong Wang, Jie Zhao, Zhe Han, Fang Tang
Pages: 1699-1707
Published online on: 07 April 2015

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Article

MicroRNA-155 modulates the proliferation of vascular smooth muscle cells by targeting endothelial nitric oxide synthase

Jun Zhang, Fei Zhao, Xiaoling Yu, Xiang Lu, Guofeng Zheng
Pages: 1708-1714
Published online on: 14 April 2015

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Article

Production of DUSP1 protein using the baculovirus insect cell expression system and its in vitro effects on cancer cells

Peng Cheng, Shuying Zhu, Li Jun, Lihua Huang, Yahui Hong
Pages: 1715-1719
Published online on: 09 April 2015

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Article

Influence of particle size on the in vitro and in vivo anti-inflammatory and anti-allergic activities of a curcumin lipid nanoemulsion

Takefumi Onodera, Isoko Kuriyama, Tooru Andoh, Hideki Ichikawa, Yuka Sakamoto, Eibai Lee-Hiraiwa, Yoshiyuki Mizushina
Pages: 1720-1728
Published online on: 16 April 2015

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Article

Interleukin-32 stimulates osteosarcoma cell invasion and motility via AKT pathway-mediated MMP-13 expression

Yanhong Zhou, Zhaohui Hu, Ningning Li, Renjie Jiang
Pages: 1729-1733
Published online on: 31 March 2015

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Article

Metformin attenuates palmitic acid-induced insulin resistance in L6 cells through the AMP-activated protein kinase/sterol regulatory element-binding protein-1c pathway

Wenjun Wu, Sunyinyan Tang, Junfeng Shi, Wenwen Yin, Shu Cao, Ruifang Bu, Dalong Zhu, Yan Bi
Pages: 1734-1740
Published online on: 17 April 2015

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Article

Hydrogen sulfide attenuates cytokine production through the modulation of chromatin remodeling

Ester C.S. Rios, Bartosz Szczesny, Francisco G. Soriano, Gabor Olah, Csaba Szabo
Pages: 1741-1746
Published online on: 08 April 2015

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Article

Effect of zinc on high glucose-induced epithelial-to-mesenchymal transition in renal tubular epithelial cells

Xiuli Zhang, Dan Liang, Zhi-Hong Chi, Qingqing Chu, Chenghai Zhao, Rong-Zheng Ma, Yue Zhao, Hongjuan Li
Pages: 1747-1754
Published online on: 07 April 2015

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Article

OSM is overexpressed in knee osteoarthritis and Notch signaling is involved in the effects of OSM on MC3T3-E1 cell proliferation and differentiation

J. Ni, X. M. Yuan, Q. Yao, L. B. Peng
Pages: 1755-1760
Published online on: 02 April 2015

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Article

Melia azedarach extract stimulates melanogenesis through increase of tyrosinase-related protein 1 expression in B16F10 mouse melanoma cells

Cheng Yao, Cheng Long Jin, Inn Gyung Oh, Chi-Hyun Park, Jin Ho Chung
Pages: 1761-1766
Published online on: 14 April 2015

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Article

Inhibition of farnesyl pyrophosphate synthase attenuates angiotensin II-induced fibrotic responses in vascular smooth muscle cells

Chang-Qing Du, Xiao-Wei Liu, Guang-Zhong Zeng, Hong-Feng Jin, Li-Jiang Tang
Pages: 1767-1772
Published online on: 02 April 2015

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Article

Suppressive effects of exogenous regucalcin on the proliferation of human pancreatic cancer MIA PaCa-2 cells in vitro

Masayoshi Yamaguchi, Tomiyasu Murata
Pages: 1773-1778
Published online on: 01 April 2015

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Article

Quercetin prevents adipogenesis by regulation of transcriptional factors and lipases in OP9 cells

Yun-Soo Seo, Ok-Hwa Kang, Sung-Bae Kim, Su-Hyun Mun, Da-Hye Kang, Da-Wun Yang, Jang-Gi Choi, Young-Mi Lee, Dae-Kil Kang, Ho-Seog Lee, Dong-Yeul Kwon
Pages: 1779-1785
Published online on: 15 April 2015

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Journal Cover
November-2026 Volume 58 Issue 5

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Journal Metrics

Impact Factor: 8.5

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

Spatial multi‑omics identifies an SPP1+ macrophage‑driven anti‑apoptotic niche in osteoarthritis synovium via the SPP1‑CD44 axis

Han Gong, Hao Shen, Feng Zhang, Wei Wang, Sheng Zhou, Lei Wang, Yu Sun
Article Number: 334
Published online on: 29 September 2026

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Review Open Access

Novel insights into the role of the renal interstitial microenvironment in Randall's plaque formation (Review)

Jialiang Wang, Zhangcheng Liao, Minghui Liu, Yizhou Wang, Yu Cui, Hequn Chen, Feng Zeng, Zewu Zhu
Article Number: 333
Published online on: 29 September 2026

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Correction Open Access

[Corrigendum] Alteration of the Wnt/GSK3β/β‑catenin signalling pathway by rapamycin ameliorates pathology in an Alzheimer's disease model

Jingfei Chen, Zhimin Long, Yanzhen Li, Min  Luo, Shifang  Luo, Guiqiong He
Article Number: 332
Published online on: 28 September 2026

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Article Open Access

miR‑222‑3p inhibits diabetic skin wound healing by targeting APLN

Ruyan Jie, Ying Tang, Tingting Wu, Chenfan Zhang, Man Song, Xiaotong Zhao, Mingwei Chen
Article Number: 331
Published online on: 25 September 2026

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Correction Open Access

[Corrigendum] Adjudin delays cellular senescence through Sirt3‑mediated attenuation of ROS production

Keyi Geng, Ningzhen Fu, Xiao Yang, Weiliang Xia
Article Number: 330
Published online on: 23 September 2026

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Article Open Access

Salidroside attenuates myocardial ischemia‑reperfusion‑induced oxidative stress and ferroptosis by promoting USP11‑mediated  deubiquitination of PRDX2

Zhi-Cong Qiu, Jian-Nan Li, Yi-Zhou Li, Zi-Ming Wu, Xu-Dong Luo, Rui-Yuan Zeng, Song-Qing Lai, Shi-Tao Zhao, Li Wan
Article Number: 329
Published online on: 23 September 2026

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Review Open Access

Reprogramming of cell death in gastric cancer: From molecular mechanisms to therapeutic potential (Review)

Mengru Liu, Zhujun Wu, Qiao Chen, Weiguo Ni, Ying Chen, Yixin Zhu, Yu Chen, Haifeng Ma, Yan Lin
Article Number: 328
Published online on: 23 September 2026

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Article Open Access

Remimazolam attenuates myocardial ischemia/reperfusion injury by inhibiting ferroptosis involving the AKT/SLC7A11/GPX4 axis

Xiyuan Chen, Jianghong Zhao, Xingtong He, Yuqi Zhang, Jiao Wu, Chao Jiang, Yi Yang, Ji Xiao
Article Number: 327
Published online on: 22 September 2026

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Review Open Access

Tumor‑immune spatiotemporal co‑evolution: A new paradigm for understanding and overcoming therapy resistance in metastatic castration‑resistant prostate cancer (Review)

Li Yan, Xiaoke Sun, Pengxiao Su
Article Number: 326
Published online on: 21 September 2026

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Review Open Access

Research progress on the role of IL‑37 in gynecological and obstetrics‑related diseases (Review)

Hongjing Wang, Renukha Arjune, Weiyu Gan, Na Guo, Nan Yu, Ting Xiong
Article Number: 325
Published online on: 21 September 2026

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Expression of Concern Open Access

[Expression of Concern] PAT protein mRNA expression in primary rat hepatocytes: Effects of exposure to fatty acids

Elena Grasselli, Adriana Voci, Carlo Pesce, Laura Canesi, Emilia Fugassa, Gabriella Gallo, Laura Vergani
Article Number: 324
Published online on: 21 September 2026

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Review Open Access

Neutrophil extracellular traps in cardiovascular disease: Mechanisms and therapeutic implications (Review)

Zhao Wang, Mingde Chang, Wenyu Shang, Yunfeng Jia, Xiaoyu Shan, Xinnong Chen, Yingxi Yang, Junping Zhang
Article Number: 323
Published online on: 18 September 2026

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Article Open Access

Sirt1 attenuates calcific aortic valve disease by inhibiting ferroptosis and enhancing mitochondrial function via the activation of the Nrf2/HO‑1/FTH1 axis

Fei Yan, Lei Shi, Yuechan Wang, Ying Zhao, Yuanyuan Wu, Dubiao Xian, Yunheng Liang, Ning Wang, Hongwang Cui, Minni Zhang
Article Number: 322
Published online on: 18 September 2026

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Article Open Access

Ketogenic diet attenuates Müller cell activation and retinal neuroinflammation in autoimmune glaucoma through acetylation‑mediated FOXO signalling

Sisi Tan, Xiaochen Wang, Yunfan Zheng, Zhenni Mou, Lihong Zeng, Jingchang Yuan, Xiao Fan, Miao Wei, Yujia Huo, Ruotong Ouyang, Yanyu Pu, Junqin Lei, Xi Gao, Dangdang Wang, Yang Peng, Hong Li
Article Number: 321
Published online on: 17 September 2026

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Review Open Access

ILC3s as central regulators of mucosal homeostasis and disease pathogenesis (Review)

Jingwen Zhang, Lili Bao, Jiaxi Li, Xia Li, Lu Qiao, Jiaxian Cui, Xiaoxia He, Mingyu Zhang, Jingkun Lu, Xuan Zhang, Jing Dong, Gesi Tao, Yaoqing Feng, Yun Peng Tian, Pengwei Zhao, Ya Tuo
Article Number: 320
Published online on: 17 September 2026

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Review Open Access

Small extracellular vesicles in osteoarthritis: A double‑edged sword regulating inflammation and cartilage homeostasis (Review)

Yifan Yang, Jiachen Liang, Xiangyu Shi, Anqi Niu, Ruifang Gao, Xiuping Wu, Xiaojuan Guo, Xiaotong Shi, Kejie Cao, Bing Li, Ran Li
Article Number: 319
Published online on: 17 September 2026

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Review Open Access

Exosomal circular RNAs in the tumor immune microenvironment: From regulatory mechanisms to therapeutic opportunities and translational hurdles (Review)

Wenlong Zhang, Nuo Chen, Liya Gong, Yu Dong, Hui Shen, Xin Liu, Jie Sun, Luxuan Liu, Zhe Jin, Liaoyuan Wang, Xue Han, Bin Zhang, Shuixing Zhang
Article Number: 318
Published online on: 17 September 2026

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Expression of Concern Open Access

[Expression of Concern] Ginsenoside Rg1 protects against H2O2‑induced neuronal damage due to inhibition of the NLRP1 inflammasome signalling pathway in hippocampal neurons in vitro

Tan-Zhen Xu, Xiao-Yan Shen, Ling-Ling Sun, Ya-Li Chen, Bi-Qiong Zhang, Da-Ke Huang, Wei-Zu Li
Article Number: 317
Published online on: 16 September 2026

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Review Open Access

tRNA‑derived RNAs in hepatic diseases: From biological functions to clinical translation (Review)

Yaotian Cai, Yifei Chen, Fuji Yang, Yongmin Yan, Ting Jiang
Article Number: 316
Published online on: 15 September 2026

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Review Open Access

Monocytes in pneumonia: Functional plasticity and innate memory (Review) 

Run-Ze Li, Zhi-Han Xie, Li Chen, Yun-Xiao Shang, Fei Wang, Wan-Jie Huang, Qi Cheng
Article Number: 315
Published online on: 15 September 2026

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Correction Open Access

[Corrigendum] Integrative transcriptomic analysis unveils FXR as a key regulator of intestinal stemness and inflammation in ulcerative colitis

Hao Lin, Xinran Cheng, Yangyang Ren, Yongmei Zhang, Weixu Chen, Qingyan Lu, Yiqing Tian
Article Number: 314
Published online on: 14 September 2026

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Ferroptosis in heatstroke: Mechanisms and therapeutic perspectives (Review)

Hongguang Gao, Yang Chen, Tianshan Zhang, Yujun Shi, Rong Yao
Article Number: 313
Published online on: 10 September 2026

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Correction Open Access

[Corrigendum] Inactivation of von Hippel‑Lindau increases ovarian cancer cell aggressiveness through the HIF1α/miR‑210/VMP1 signaling pathway

Ting Liu, Le Zhao, Wei Chen, Zhen Li, Huilian Hou, Lu Ding, Xu Li
Article Number: 312
Published online on: 10 September 2026

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Interferon regulatory factors orchestrate CD8+ T cell function (Review)

Fa-Xi Wang, Chun-Liang Yang, Shan-Jie Rong, Qi-Jie Chen, Xiong-Tao Yue, Fei Sun
Article Number: 311
Published online on: 08 September 2026

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Expression of Concern Open Access

[Expression of Concern] Rapamycin‑induced miR‑30a downregulation inhibits senescence of VSMCs by targeting Beclin1

Pan Tan, Haiqin Wang, Junkun Zhan, Xinyu Ma, Xingjun Cui, Yanjiao Wang, Yi Wang, Jiayu Zhong, Youshuo Liu
Article Number: 310
Published online on: 07 September 2026

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Deciphering the function and mechanism of extracorporeal shock wave therapy in knee osteoarthritis (Review)

Yixuan Chen, Siqi Song, Yuchen Zhu, Shiqi Wang, Jieyuan Hu, Chenxu Liu, Yuchen Cai, Yushi Hu
Article Number: 309
Published online on: 04 September 2026

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Multi‑omics integration in osteoarthritis: Unraveling cell‑type‑specific gene‑metabolite networks for precision medicine (Review)

Ying Yang, Ruichen Zheng, Yun Zhang, Dongmei Ye, Jiale Xie, Changliang Zhu
Article Number: 308
Published online on: 03 September 2026

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Autophagy determines the fate of immune cells by regulating metabolic remodeling and PANoptosis (Review)

Yanan Guo, Xinyue Zhou, Yixiao Tian, Dan Chen, Xiaofeng Xie, Bin Zhou, Yingxia Tian, Yaqing Zhang
Article Number: 307
Published online on: 03 September 2026

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Programmed cell death in metabolic syndrome: From molecular mechanisms to therapeutic strategies (Review)

Jialin Zhong, Maofu Zhang, Yafang Zheng, Cuicui Gong, Yasheng Deng, Lisha Sun, Dongqi Zhou, Qian Zhou, Qiu Chen
Article Number: 306
Published online on: 03 September 2026

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Research progress on lysine acetylation (Review)

Minghui Zhang, Yuqi Zhang, Haoxin Yin, Junyuan Yan, Yingling Dong, Xin Zhao, Tianyi Cui, Bin Lv, Xiumei Gao
Article Number: 305
Published online on: 02 September 2026

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Expression of Concern Open Access

[Expression of Concern] Human ether‑à‑go‑go‑related gene mutation L539fs/47‑hERG leads to cell apoptosis through the endoplasmic reticulum stress pathway

Shuting Ma, Yun Zhao, Miaomiao Cao, Chaofeng Sun
Article Number: 304
Published online on: 02 September 2026

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Targeting integrated cell death networks in sepsis‑associated acute kidney injury: Shared regulatory nodes and diet‑related small molecule modulation (Review)

Lin Song, Aifeng He, Wei Jiang, Keran Shi, Jing Wang, Lu Xu, Jiangquan Yu, Ruiqiang Zheng
Article Number: 303
Published online on: 31 August 2026

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Article Open Access

Effect of MALT1 inhibition by MI‑2 on the microglial phenotype switch, inflammatory cytokine secretion, neuronal loss and oxidative stress in Alzheimer's disease

Yuanlong Li, Hua Fan, Xiong Han, Ming Ni, Xiaodan Hou, Hailan Xia, Yinzhu Shi, Lin Zhang, Jun Sun
Article Number: 302
Published online on: 31 August 2026

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Salvianolic acid monomers against metastasis: Decoding the multilayered interception of EMT, angiogenesis and immune evasion (Review)

Shiting Jiang, Dan Liu, Tingting Wei, Qiwei Shi, Haowen Wang, Yidan Gao, Pingsu Mao, Wenli Yang
Article Number: 301
Published online on: 31 August 2026

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Retraction Open Access

[Retracted] Silencing of decoy receptor 3 (DcR3) expression by siRNA in pancreatic carcinoma cells induces Fas ligand‑mediated apoptosis in vitro and in vivo

Jian Zhou, Shiduo Song, Songbin He, Zhenxin Wang, Bing Zhang, Dechun Li, Dongming Zhu
Article Number: 300
Published online on: 31 August 2026

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Research progress on BTG2 in non‑tumor diseases (Review)

Shuling Li, Xiaomei Liu, Zheng Zhang, Ling Yang, Yuxuan Li, Qiongdan Hu
Article Number: 299
Published online on: 28 August 2026

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Breaking the cycle of fibrosis: Ferroptosis as a therapeutic target (Review)

Xincheng Feng, Jue Zhang, Qinghong Ma, Chao Sun
Article Number: 298
Published online on: 27 August 2026

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Correction Open Access

[Corrigendum] Tumor‑targeting novel manganese complex induces ROS‑mediated apoptotic and autophagic cancer cell death

Jia Liu, Wenjie Guo, Jing Li, Xiang Li, Ji Geng, Qiuyun Chen, Jing Gao
Article Number: 297
Published online on: 26 August 2026

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Advances in sirtuin research in lung diseases (Review)

Shuangyun Xi, Weijun Chen, Xiuli Li, Yudan Wang, Yong Ke
Article Number: 296
Published online on: 25 August 2026

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Article Open Access

lncRNA TUG1 mediates palmitic acid‑induced neuronal lipotoxic injury via the miR‑449a‑5p/caspase‑3 and Akt/GSK‑3β axes

Ya-Dong Wei, Peng-Quan Chen, Xin Zheng, Le-Qi Wu, Xin-Yi Wang, Xin-Ran Gao, Jin-Fang Ge
Article Number: 295
Published online on: 25 August 2026

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Retraction Open Access

[Retracted] Downregulation of LINC00707 promotes osteogenic differentiation of human bone marrow‑derived mesenchymal stem cells by regulating DKK1 via targeting miR‑103a‑3p

Jun Liu, Minfei Wu, Guang Feng, Rui Li, Yang Wang, Jianhang Jiao
Article Number: 294
Published online on: 24 August 2026

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December-2026 Volume 58 Issue 6

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Journal Metrics

Impact Factor: 8.5

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Centrosomal protein 55: Research progress on biological characteristics, disease associations and clinical translational potential (Review)

Sanmei Nong, Qiudong Huang, Kuibo Huang, Xiao Luo, Yin Huang, Wenlian Zheng, Weiyi Huang, Zhaoyun Liu
Article Number: 346
Published online on: 16 October 2026

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Multiple strategies to improve the therapeutic efficacy of mesenchymal stem cell‑derived exosome transplantation in ischemic stroke (Review)

Yan Xu, Xiaolei Zhou, Wenhui Zeng, Jiabing Wang, Lin Zhou, Lincai Li, Zhengwei Zou, Cixiang Chen, Yichi Zhang, Zhengyi He, Junsong Ye
Article Number: 345
Published online on: 14 October 2026

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Article Open Access

Resveratrol alleviates osteoarthritis progression by inhibiting NLRP3 inflammasome response via the AMPK/PPARγ signaling pathway

Shanshan Cui, Zifan Luo, Wen Qin, Bo Chen, Qiaoxia Zhang, Jianbing Ma, Jie Ma, Rui Zhang
Article Number: 344
Published online on: 14 October 2026

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Expression of Concern Open Access

[Expression of Concern] Anti‑metastatic and differential effects on protein expression of epigallocatechin‑3‑gallate in HCCLM6 hepatocellular carcinoma cells

Yunjuan Zhang, Lawrence Owusu, Wei Duan, Tao Jiang, Shizhu Zang, Ayaz Ahmed, Yi Xin
Article Number: 343
Published online on: 14 October 2026

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Article Open Access

Six3 promoting the migration and neural differentiation of BMSCs via Btg2‑mediated Akt signaling pathway activation: A therapeutic strategy for stroke

Zhenqiang Fu, Zhixin Li, Limin Zhang, Wentao Hu, Hecheng Yang, Jingtao Wang
Article Number: 342
Published online on: 12 October 2026

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Expression of Concern Open Access

[Expression of Concern] EETs and CYP2J2 inhibit TNF‑α‑induced apoptosis in pulmonary artery endothelial cells and TGF‑β1‑induced migration in pulmonary artery smooth muscle cells

Wenjing Feng, Xizhen Xu, Gang Zhao, Geng Li, Tiantian Liu, Junjie Zhao, Ruolan Dong, Dao Wen Wang, Ling Tu
Article Number: 341
Published online on: 12 October 2026

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Gomisin A as a multi‑target therapeutic agent: Pharmacological mechanisms, pharmacokinetics and network pharmacology (Review)

Jiaqi Xu, Sha Shi, Chengkai Zhu, Qi Sui, Shanhao Zhu, Jingnan Zhang, Yi Zhang, Peng Chen
Article Number: 340
Published online on: 09 October 2026

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Multi‑target mechanisms of paeoniflorin in inflammatory regulation: A network pharmacology (Review)

Jin Zhang, Junjie Ye, Kun Jin, Xuan Sun, Xinyu Yu, Yuan Zhao, Ni Zhu
Article Number: 339
Published online on: 09 October 2026

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Mechanisms of neuroimmune crosstalk in vestibular disorders: Linking inflammation with neural circuit dysfunction (Review)

Xianfang Pan, Jin Fan, Zhiyi Yang, Zegang Yin, Zhen Li, Zhifeng Rui, Hujun Zhang, Yujie Li, Hongjuan Zhang
Article Number: 338
Published online on: 08 October 2026

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Expression of Concern Open Access

[Expression of Concern] Gambogic acid inhibits invasion of osteosarcoma via upregulation of TIMP‑1

Zeng-Feng Xin, Cheng-Chun Shen, Li-Jiang Tao, Shi-Gui Yan, Hao-Bo Wu
Article Number: 337
Published online on: 08 October 2026

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Anesthetics and cancer biology: Translational evidence from perioperative modulation to drug repurposing (Review)

Ting Yang, Jiao Tang, Muhammad Saqib Mudabbar, Huan Hu, Qiang Fu, Chunlan Pu
Article Number: 336
Published online on: 05 October 2026

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Expression of Concern Open Access

[Expression of Concern] Multiple roles of SOCS proteins: Differential expression of SOCS1 and SOCS3 in atherosclerosis

Xiao Liang, Ming He, Tao Chen, Yan Liu, Yu-Ling Tian, Yu-Liang Wu, Yan Zhao, Yan Shen, Zu-Yi Yuan
Article Number: 335
Published online on: 30 September 2026

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