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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
June-2015 Volume 35 Issue 6

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

The utility of mouse models to provide information regarding the pathomolecular mechanisms in human genetic skeletal diseases: The emerging role of endoplasmic reticulum stress (Review)

Michael D. Briggs, Peter A. Bell, Katarzyna A. Pirog
Pages: 1483-1492
Published online on: 30 March 2015

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Review

Retinoic acid-related orphan receptor RORβ, circadian rhythm abnormalities and tumorigenesis (Review)

Shujiong Feng, Song Xu, Zhenzhen Wen, Yongliang Zhu
Pages: 1493-1500
Published online on: 26 March 2015

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Article Open Access

Elevated survivin expression in peripheral blood mononuclear cells is central to collateral formation in coronary chronic total occlusion

Yiguan Xu, Xuerui Tan, Dongming Wang, Wei Wang, Yuguang Li, Min Wu, Songming Chen, Yinge Wu, Chunjiang Tan
Pages: 1501-1510
Published online on: 24 March 2015

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Article Open Access

Maternal peripheral blood natural killer cells incorporate placenta-associated microRNAs during pregnancy

Yoichi Ishida, Dongwei Zhao, Akihide Ohkuchi, Tomoyuki Kuwata, Hiroshi Yoshitake, Kazuya Yuge, Takami Takizawa, Shigeki Matsubara, Mitsuaki Suzuki, Shigeru Saito, Toshihiro Takizawa
Pages: 1511-1524
Published online on: 27 March 2015

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Article Open Access

Silencing of uncoupling protein 2 by small interfering RNA aggravates mitochondrial dysfunction in cardiomyocytes under septic conditions

Guilang Zheng, Juanjuan Lyu, Shu Liu, Jinda Huang, Cui Liu, Dan Xiang, Meiyan Xie, Qiyi Zeng
Pages: 1525-1536
Published online on: 09 April 2015

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Article Open Access

Ischemic preconditioning protects neurons from damage and maintains the immunoreactivity of kynurenic acid in the gerbil hippocampal CA1 region following transient cerebral ischemia

Jae-Chul Lee, Hyun-Jin Tae, Geum-Sil Cho, In Hye Kim, Ji Hyeon Ahn, Joon Ha Park, Bai Hui Chen, Jeong-Hwi Cho, Bich Na Shin, Jun Hwi Cho, Eun Joo Bae, Jinseu Park, Young-Myeong Kim, Soo Young Choi, Moo-Ho Won
Pages: 1537-1544
Published online on: 07 April 2015

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Article Open Access

GATA4 transgenic mice as an in vivo model of congenital heart disease

Hua Han, Yu Chen, Gang Liu, Zengqiang Han, Zhou Zhao, Yin Tang
Pages: 1545-1553
Published online on: 09 April 2015

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Article Open Access

Application of multiplex ligation-dependent probe amplification, and identification of a heterozygous Alu-associated deletion and a uniparental disomy of chromosome 1 in two patients with 3-hydroxy-3-methylglutaryl-CoA lyase deficiency

Yuka Aoyama, Toshiyuki Yamamoto, Naomi Sakaguchi, Mika Ishige, Toju Tanaka, Tomoko Ichihara, Katsuaki Ohara, Hiroko Kouzan, Yasutomi Kinosada, Toshiyuki Fukao
Pages: 1554-1560
Published online on: 14 April 2015

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Article Open Access

Activating transcription factor 3 is overexpressed in human glioma and its knockdown in glioblastoma cells causes growth inhibition both in vitro and in vivo

Siqi Ma, Changhe Pang, Laijun Song, Fuyou Guo, Hongwei Sun
Pages: 1561-1573
Published online on: 07 April 2015

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Article Open Access

Changes in Dpysl2 expression are associated with prenatally stressed rat offspring and susceptibility to schizophrenia in humans

Hwayoung Lee, Jaesoon Joo, Seong-Su Nah, Jong Woo Kim, Hyung-Ki Kim, Jun-Tack Kwon, Hwa-Young Lee, Young Ock Kim, Hak-Jae Kim
Pages: 1574-1586
Published online on: 01 April 2015

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Article Open Access

miR‑204-5p promotes the adipogenic differentiation of human adipose-derived mesenchymal stem cells by modulating DVL3 expression and suppressing Wnt/β-catenin signaling

Honghui He, Ke Chen, Fang Wang, Liling Zhao, Xinxing Wan, Linghao Wang, Zhaohui Mo
Pages: 1587-1595
Published online on: 31 March 2015

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Article Open Access

Epigenetic repression of Krüppel-like factor 4 through Dnmt1 contributes to EMT in renal fibrosis

Xiangcheng Xiao, Wenbin Tang, Qiongjing Yuan, Ling Peng, Pingping Yu
Pages: 1596-1602
Published online on: 20 April 2015

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Article

Human neutrophil peptides induce interleukin-8 in intestinal epithelial cells through the P2 receptor and ERK1/2 signaling pathways

Kazunari Ibusuki, Toshio Sakiyama, Shuji Kanmura, Takuro Maeda, Yuji Iwashita, Yuichiro Nasu, Fumisato Sasaki, Hiroki Taguchi, Shinichi Hashimoto, Masatsugu Numata, Hirofumi Uto, Hirohito Tsubouchi, Akio Ido
Pages: 1603-1609
Published online on: 26 March 2015

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Article

Curcumin induces the apoptosis of non-small cell lung cancer cells through a calcium signaling pathway

Xudong Xu, Da Chen, Bo Ye, Fangming Zhong, Gang Chen
Pages: 1610-1616
Published online on: 02 April 2015

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Article

Combination of 12-O-tetradecanoylphorbol-13-acetate with diethyldithiocarbamate markedly inhibits pancreatic cancer cell growth in 3D culture and in immunodeficient mice

Huarong Huang, Kajia Cao, Saquib Malik, Qiuyan Zhang, Dongli Li, Richard Chang, Huaqian Wang, Weiping Lin, Jeremiah Van Doren, Kun Zhang, Zhiyun Du, Xi Zheng
Pages: 1617-1624
Published online on: 01 April 2015

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Article

Ischemic preconditioning increases GSK-3β/β-catenin levels and ameliorates liver ischemia/reperfusion injury in rats

Yichao Yan, Guangying Li, Xiaofeng Tian, Yingjiang Ye, Zhidong Gao, Jihong Yao, Feng Zhang, Shan Wang
Pages: 1625-1632
Published online on: 23 March 2015

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Article

NLRP3 inflammasome is responsible for Hantavirus inducing interleukin-1β in THP-1 cells Corrigendum in /10.3892/ijmm.2019.4155

Wei Ye, Yingfeng Lei, Mengmeng Yu, Yongni Xu, Mengyuan Cao, Lan Yu, Liang Zhang, Puyuan Li, Wentao Bai, Zhikai Xu, Fanglin Zhang
Pages: 1633-1640
Published online on: 01 April 2015

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Article

Hedgehog signaling is involved in the BMP9-induced osteogenic differentiation of mesenchymal stem cells Retraction in /10.3892/ijmm.2023.5233

Li Li, Qian Dong, Yufeng Wang, Qiaoling Feng, Pengfei Zhou, Xinying Ou, Qiurong Meng, Tongchuan He, Jinyong Luo
Pages: 1641-1650
Published online on: 07 April 2015

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Article

Effects of bee venom against Propionibacterium acnes‑induced inflammation in human keratinocytes and monocytes

Jung-Yeon Kim, Woo-Ram Lee, Kyung-Hyun Kim, Hyun-Jin An, Young-Chae Chang, Sang-Mi Han, Yoon-Yub Park, Sok Cheon Pak, Kwan-Kyu Park
Pages: 1651-1656
Published online on: 09 April 2015

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Article

Hydrogen sulfide attenuates IL-1β-induced inflammatory signaling and dysfunction of osteoarthritic chondrocytes

Chengzhi Ha, Shaoqi Tian, Kang Sun, Dawei Wang, Jiangtao Lv, Yuanhe Wang
Pages: 1657-1666
Published online on: 14 April 2015

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Article

AST Ⅳ inhibits H2O2-induced human umbilical vein endothelial cell apoptosis by suppressing Nox4 expression through the TGF-β1/Smad2 pathway

Yuhong Ma, Weizu Li, Yanyan Yin, Weiping Li
Pages: 1667-1674
Published online on: 17 April 2015

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Article

MAGE-A expression clusters and antineoplastic treatment in head and neck cancer

Stefan Hartmann, Till J. Meyer, Roman C. Brands, Imme R. Haubitz, Christian Linz, Axel Seher, Alexander C. Kübler, Urs D.A. Müller-Richter
Pages: 1675-1682
Published online on: 07 April 2015

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Article

LSm1 binds to the Dengue virus RNA 3' UTR and is a positive regulator of Dengue virus replication

Yangchao Dong, Jing Yang, Wei Ye, Yuan Wang, Yunbo Miao, Tianbing Ding, Chen Xiang, Yingfeng Lei, Zhikai Xu
Pages: 1683-1689
Published online on: 07 April 2015

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Article

Anti-inflammatory potential of saponins derived from cultured wild ginseng roots in lipopolysaccharide-stimulated RAW 264.7 macrophages

Gyeong-Jin Yu, Il-Whan Choi, Gi-Young Kim, Byung-Woo Kim, Cheol Park, Su-Hyun Hong, Sung-Kwon Moon, Hee-Jae Cha, Young-Chae Chang, Kee Yoeup Paek, Wun-Jae Kim, Yung Hyun Choi
Pages: 1690-1698
Published online on: 02 April 2015

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Article

Protective effects of Semen Crotonis Pulveratum on trinitrobenzene sulphonic acid-induced colitis in rats and H2O2-induced intestinal cell apoptosis in vitro

Xiaohong Wang, Jie Zhao, Zhe Han, Fang Tang
Pages: 1699-1707
Published online on: 07 April 2015

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Article

MicroRNA-155 modulates the proliferation of vascular smooth muscle cells by targeting endothelial nitric oxide synthase

Jun Zhang, Fei Zhao, Xiaoling Yu, Xiang Lu, Guofeng Zheng
Pages: 1708-1714
Published online on: 14 April 2015

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Article

Production of DUSP1 protein using the baculovirus insect cell expression system and its in vitro effects on cancer cells

Peng Cheng, Shuying Zhu, Li Jun, Lihua Huang, Yahui Hong
Pages: 1715-1719
Published online on: 09 April 2015

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Article

Influence of particle size on the in vitro and in vivo anti-inflammatory and anti-allergic activities of a curcumin lipid nanoemulsion

Takefumi Onodera, Isoko Kuriyama, Tooru Andoh, Hideki Ichikawa, Yuka Sakamoto, Eibai Lee-Hiraiwa, Yoshiyuki Mizushina
Pages: 1720-1728
Published online on: 16 April 2015

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Article

Interleukin-32 stimulates osteosarcoma cell invasion and motility via AKT pathway-mediated MMP-13 expression

Yanhong Zhou, Zhaohui Hu, Ningning Li, Renjie Jiang
Pages: 1729-1733
Published online on: 31 March 2015

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Article

Metformin attenuates palmitic acid-induced insulin resistance in L6 cells through the AMP-activated protein kinase/sterol regulatory element-binding protein-1c pathway

Wenjun Wu, Sunyinyan Tang, Junfeng Shi, Wenwen Yin, Shu Cao, Ruifang Bu, Dalong Zhu, Yan Bi
Pages: 1734-1740
Published online on: 17 April 2015

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Article

Hydrogen sulfide attenuates cytokine production through the modulation of chromatin remodeling

Ester C.S. Rios, Bartosz Szczesny, Francisco G. Soriano, Gabor Olah, Csaba Szabo
Pages: 1741-1746
Published online on: 08 April 2015

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Article

Effect of zinc on high glucose-induced epithelial-to-mesenchymal transition in renal tubular epithelial cells

Xiuli Zhang, Dan Liang, Zhi-Hong Chi, Qingqing Chu, Chenghai Zhao, Rong-Zheng Ma, Yue Zhao, Hongjuan Li
Pages: 1747-1754
Published online on: 07 April 2015

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Article

OSM is overexpressed in knee osteoarthritis and Notch signaling is involved in the effects of OSM on MC3T3-E1 cell proliferation and differentiation

J. Ni, X. M. Yuan, Q. Yao, L. B. Peng
Pages: 1755-1760
Published online on: 02 April 2015

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Article

Melia azedarach extract stimulates melanogenesis through increase of tyrosinase-related protein 1 expression in B16F10 mouse melanoma cells

Cheng Yao, Cheng Long Jin, Inn Gyung Oh, Chi-Hyun Park, Jin Ho Chung
Pages: 1761-1766
Published online on: 14 April 2015

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Article

Inhibition of farnesyl pyrophosphate synthase attenuates angiotensin II-induced fibrotic responses in vascular smooth muscle cells

Chang-Qing Du, Xiao-Wei Liu, Guang-Zhong Zeng, Hong-Feng Jin, Li-Jiang Tang
Pages: 1767-1772
Published online on: 02 April 2015

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Article

Suppressive effects of exogenous regucalcin on the proliferation of human pancreatic cancer MIA PaCa-2 cells in vitro

Masayoshi Yamaguchi, Tomiyasu Murata
Pages: 1773-1778
Published online on: 01 April 2015

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Article

Quercetin prevents adipogenesis by regulation of transcriptional factors and lipases in OP9 cells

Yun-Soo Seo, Ok-Hwa Kang, Sung-Bae Kim, Su-Hyun Mun, Da-Hye Kang, Da-Wun Yang, Jang-Gi Choi, Young-Mi Lee, Dae-Kil Kang, Ho-Seog Lee, Dong-Yeul Kwon
Pages: 1779-1785
Published online on: 15 April 2015

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Journal Cover
March-2026 Volume 57 Issue 3

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

Ginkgolide C alleviates atherosclerosis via activating Nrf2 to inhibit ROS‑dependent NLRP3 inflammasome activation

Rui Zhang
Article Number: 75
Published online on: 27 January 2026

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Review Open Access

MicroRNA‑microbiome cross‑kingdom networks drive inflammatory bowel disease through dynamic regulatory ecosystems (Review)

Liping Liang, Xiaoyan Liu, Bang Li, Huyi Lei, Zibo Tang, Shijie Mai, Chenghai Yang, Yongjian Zhou, Shaoheng Zhang, Le Liu
Article Number: 74
Published online on: 27 January 2026

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Review Open Access

Mechanistic insights into pancreatic cancer progression from circadian rhythm disruption and gut microbiota dysbiosis (Review)

Yang Liu, Yongfeng Li, Heng Ma, Shichang Deng, Chao Cheng
Article Number: 73
Published online on: 26 January 2026

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Retraction Open Access

[Retracted] miR‑124‑3p inhibits the viability and motility of glioblastoma multiforme by targeting RhoG  

Shan Cai, Chao-Jia Shi, Jian-Xiang Lu, Yan-Pei Wang, Tian Yuan, Xiang-Peng Wang
Article Number: 72
Published online on: 26 January 2026

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Review Open Access

Natural products as multi‑target therapies for sepsis‑induced myocardial dysfunction (Review)

Fei Tang, Dong Liu, Shi-Chao Zhu, Hui-Min Zhou, Xue-Wen Qiu
Article Number: 71
Published online on: 22 January 2026

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Review Open Access

MTHFR‑folate axis as a modulator of the epigenetic landscape in autoimmune diseases (Review)

Pablo Michael Navarro‑Rodríguez, Ramón Francisco Bajeca‑Serrano, Francisco Javier Turrubiates‑Hernández, Hazael Ramiro Ceja‑Gálvez, Jorge Hernández‑Bello, Cristian Oswaldo Hernández‑Ramírez, Saúl Ramírez‑de Los Santos, José Francisco Muñoz‑Valle
Article Number: 70
Published online on: 22 January 2026

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Article Open Access

Natural compound 5,7,8‑trimethoxyflavone mitigates radiation‑induced lung injury by suppressing EMT and PI3K/Akt pathway

Cui-Cui Gong, Hua-Kang Li, Yuan-Zhen Mi, Jun-Yang Chen, Zeng-Yi Fang, Shun-Lian Fu, Li Quan, Bing Lin, Jin-Yi Lang, Qiu Chen, Ke Xu, Mei-Hua Chen
Article Number: 69
Published online on: 21 January 2026

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Review Open Access

Epigenetic dysregulation of B‑cells in autoimmune diseases and lymphomas (Review)

Yuxing Li, Yujiao Gong, Jiaxing Zhao, Rensen Ran
Article Number: 68
Published online on: 21 January 2026

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Review Open Access

Research progress on the effects of macrophage‑derived exosomes on muscle factors IGF‑1 and FGF‑2 mediating musculoskeletal crosstalk molecular signaling pathway on bone metabolism (Review)

Ruo-Mei Cui, Mai Zheng, Jian-Bin Hong, Zheng-Xiang Wang, Yu-Fang Cun, Shu-Ji Gao, Yan-Lin Zhu, Zi-Bin Yang, Ming-Wei Liu
Article Number: 67
Published online on: 21 January 2026

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Expression of Concern Open Access

[Expression of Concern] Long non‑coding RNA SNHG20 promotes bladder cancer via activating the Wnt/β‑catenin signalling pathway

Qingsong Zhao, Saiyue Gao, Qingyan Du, Ye Liu
Article Number: 66
Published online on: 21 January 2026

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Review Open Access

Mangiferin in human disease: Multifaceted mechanisms and applications (Review)

Yaling Dai, Qiuling Huang, Mengquan Tan, Zhifu Wang, Cai Jiang, Zheng Liu, Shenghang Zhang, Siyuan Song
Article Number: 65
Published online on: 21 January 2026

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Article

Deciphering the CAF‑LCN2 axis: Key to overcoming anti‑PD‑L1 immunotherapy resistance in lung cancer

Dan Xiao, Jing Yang, Jianying Zhou, Zhenzhen Hu, Ting Zhang
Article Number: 64
Published online on: 19 January 2026

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Retraction Open Access

[Retracted] DDAH2 alleviates myocardial fibrosis in diabetic cardiomyopathy through activation of the DDAH/ADMA/NOS/NO pathway in rats

Zhen-Dong Zhu, Ji-Ming Ye, Xue-Mei Fu, Xue-Chang Wang, Ji-Yun Ye, Xin-Ran Wu, Peng Hua, Yu-Qiong Liao, Wei Xuan, Jin-Lan Duan, Wei-Yuan Li, Hui Fu, Zhong-Hua Xia, Xuan Zhang
Article Number: 63
Published online on: 19 January 2026

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Review Open Access

Beyond hepatic stellate cell heterogeneity: Resolving fibrosis, restoring regeneration (Review)

Chang Gao, Guiqing Chen, Hongyan Jia, Hong Zhu, Yun Cai, Dakai Yang, Kai Zhao
Article Number: 62
Published online on: 14 January 2026

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Correction Open Access

[Corrigendum] CDKN2A (p16INK4A) affects the anti‑tumor effect of CDK inhibitor in somatotroph adenomas

Yiyuan Chen, Zhenye Li, Qiuyue Fang, Hongyun Wang, Chuzhong Li, Hua Gao, Yazhuo Zhang
Article Number: 61
Published online on: 14 January 2026

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Review Open Access

Harnessing MSC‑derived exosomes to modulate the pathophysiology of ASD: Recent advances and therapeutic implications (Review)

Zhaojian Sun, Nouman Amjad, Majid Muhammad, Zhiyuan Li
Article Number: 60
Published online on: 13 January 2026

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Retraction Open Access

[Retracted] Mechanism of cell death induced by silica nanoparticles in hepatocyte cells is by apoptosis

Ye Yang, Xinjing Du, Qiang Wang, Jianwei Liu, Enguo Zhang, Linlin Sai, Cheng Peng, Martin F. Lavin, Abrey Jie Yeo, Xu Yang, Hua Shao, Zhongjun Du
Article Number: 59
Published online on: 12 January 2026

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Review Open Access

ZG16B: A key regulator of tumor progression and immune microenvironment modulation in cancer (Review)

Xing-Ming Chen, Yu-Bo Liang, Jin-Xiang Zuo, Zi-Sheng Yang, Le-Yu Zhang, Xin-Yu Zhang, Ping Wan, Yang Ke
Article Number: 58
Published online on: 09 January 2026

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Retraction Open Access

[Retracted] Silica nanoparticles induce cardiomyocyte apoptosis via the mitochondrial pathway in rats following intratracheal instillation

Zhongjun Du, Shangya Chen, Guanqun Cui, Ye Yang, Enguo Zhang, Qiang Wang, Martin F. Lavin, Abrey J. Yeo, Cunxiang Bo, Yu Zhang, Chao Li, Xiaoshan Liu, Xu Yang, Cheng Peng, Hua Shao
Article Number: 57
Published online on: 05 January 2026

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Review Open Access

Role of cuproptosis in digestive system tumors (Review)

Li Zhang, Yongpeng Cheng, Lulu Tang, Jiaxing Zhu, Biguang Tuo
Article Number: 56
Published online on: 02 January 2026

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Review Open Access

Environmental exposure to air pollution and climate: Intersecting the impact on ear and nose health and chemosensory function (Review)

Yu-Chen Zhang, Lei Zhang, Ping-Ting Zhou, Zi-Hui Xie, Wen-Jie Zhang, Min Fan, Yan-Xun Han, Ye-Hai Liu, Yu-Chen Liu
Article Number: 55
Published online on: 31 December 2025

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Review Open Access

Role and mechanisms of ferroptosis in cognitive impairment: From molecular pathways to therapeutic targets (Review)

Shenghui Ge, Deyue Kong, Shuyue Fan, Yi Luo, Xiao Yin, Zehua Jin, Wenqing Xia, Jianhua Ma
Article Number: 54
Published online on: 30 December 2025

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Review Open Access

The GPR124‑Wnt‑PPARγ regulatory axis: Molecular mechanisms and therapeutic implications in chronic inflammatory diseases (Review)

Ming-Wang Cui, Si-Yu Tao, Tao Wen, Zhu-Ling Guo
Article Number: 53
Published online on: 30 December 2025

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Review Open Access

Advances in RPGR gene therapy for X‑linked retinitis pigmentosa: From preclinical insights to clinical application (Review)

Yushan Long, Jia Qi, Wenliang Zhang, Huan Qin, Kai Yao
Article Number: 52
Published online on: 30 December 2025

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April-2026 Volume 57 Issue 4

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Role of vascular smooth muscle cell pathobiology in sepsis‑induced vasoplegia (Review)

Hang Ruan, Xiao-Yan Shen, Shi-Yan Liu, Shu-Sheng Li
Article Number: 87
Published online on: 06 February 2026

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Signalling pathways regulated by FSTL1 in inflammation and potential therapeutic applications (Review)

Changliang Ma, Jingxin Li, Wenting Jiang, Xiaoqiang Chen, Jianquan Liu, Xu Tao, Wencui Li, Zhiqin Deng, Zhe Zhao
Article Number: 86
Published online on: 05 February 2026

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Article Open Access

Hypothermic machine perfusion protects DCD graft liver from ischemia‑reperfusion injury by enhancing macrophage efferocytosis via KLF2‑NLRP3 signaling

Qin Deng, Zhongzhong Liu, Qifa Ye, Jia Liu, Zhihui Fu, Xingjian Zhang, Jun Luo, Zhongshan Lu, Pengpeng Yue, Jiansheng Xiao, Qi Xiao
Article Number: 85
Published online on: 05 February 2026

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Mechanistic advances in exercise‑mediated regulation of autophagy dysfunction in Alzheimer's disease (Review)

Wei Li, Wen-Hong Wang, Yi Song, Xu-Jiong Li, Yan Li, Xia Wang, Ting-Ting Tian, Xiao Huang, Li Zhao
Article Number: 84
Published online on: 04 February 2026

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Correction Open Access

[Corrigendum] p57KIP2‑mediated inhibition of human trophoblast apoptosis and promotion of invasion in vitro

Guo-Qian He, Guang-Yu Liu, Wen-Ming Xu, Hui-Juan Liao, Xing-Hui Liu, Guo-Lin He
Article Number: 83
Published online on: 04 February 2026

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Review Open Access

Lipid droplets beyond storage: Cellular metabolic modulator in the diabetic heart (Review)

Yongchun Liang, Xinbiao Fan, Xiaofei Geng, Yunfeng Jia, Wenyu Shang, Xitong Sun, Jun Ge, Guijun Ye, Boyu Zhu, Zheng Zhang, Yuxin Kang, Xiaoyu Shan, Junping Zhang
Article Number: 82
Published online on: 03 February 2026

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IMP metabolic mechanisms and IMPDH targeting strategies in tumor metabolic reprogramming and therapy (Review)

Hao Zhu, Hao Wang, Xia Li, Weisong Zhang, Yihao Wang, Qingze Tan, Dongxu Ying, Zhan Shi, Jianxiang Song
Article Number: 81
Published online on: 03 February 2026

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Article Open Access

Ebastine targets HER2/HER3 signaling and cancer stem cell traits to overcome trastuzumab resistance in HER2‑positive breast cancer

Eunsun Jung, Ji Young Kim, Dongmi Ko, Juyeon Seo, Sang Yoon Lee, Daeun Lee, Subeen Kim, Minsu Park, Seongjae Kim, Soeun Park, Kyoungmin Lee, Yong Koo Kang, Kee Dal Nam, Yoon-Jae Kim, Jae Hong Seo
Article Number: 80
Published online on: 02 February 2026

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Correction Open Access

[Corrigendum] Inhibition of acid‑sensing ion channel 1a attenuates acid‑induced activation of autophagy via a calcium signaling pathway in articular chondrocytes

Wen-Fan Gao, Ya-Yun Xu, Jin-Fang Ge, Fei-Hu Chen
Article Number: 79
Published online on: 02 February 2026

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Immunological mechanisms and novel therapeutic strategies for sepsis‑associated acute kidney injury (Review)

Lu Xu, Wei Jiang, Lin Song, Jing Wang, Jiangquan Yu, Ruiqiang Zheng
Article Number: 78
Published online on: 30 January 2026

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Correction Open Access

[Corrigendum] Role of Smad3 signaling in the epithelial‑mesenchymal transition of the lens epithelium following injury

Fanlan Meng, Jun Li, Xiao Yang, Xiaoyong Yuan, Xin Tang
Article Number: 77
Published online on: 29 January 2026

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Review Open Access

Spatial metabolomics: A new tool for unravelling the metabolic disorders and heterogeneity in diabetic kidney disease (Review)

Hanfei Li, Yuxi Li, Bo Zhang, Wenhao Cheng, Guowei Ma, Jin Rong, Shiru Duan, Di Feng, Tingting Zhao
Article Number: 76
Published online on: 29 January 2026

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