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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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International Journal of Molecular Medicine

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
June-2015 Volume 35 Issue 6

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Journal Metrics

Impact Factor: 5.8

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

The utility of mouse models to provide information regarding the pathomolecular mechanisms in human genetic skeletal diseases: The emerging role of endoplasmic reticulum stress (Review)

Michael D. Briggs, Peter A. Bell, Katarzyna A. Pirog
Pages: 1483-1492
Published online on: 30 March 2015

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Review

Retinoic acid-related orphan receptor RORβ, circadian rhythm abnormalities and tumorigenesis (Review)

Shujiong Feng, Song Xu, Zhenzhen Wen, Yongliang Zhu
Pages: 1493-1500
Published online on: 26 March 2015

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Article Open Access

Elevated survivin expression in peripheral blood mononuclear cells is central to collateral formation in coronary chronic total occlusion

Yiguan Xu, Xuerui Tan, Dongming Wang, Wei Wang, Yuguang Li, Min Wu, Songming Chen, Yinge Wu, Chunjiang Tan
Pages: 1501-1510
Published online on: 24 March 2015

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Article Open Access

Maternal peripheral blood natural killer cells incorporate placenta-associated microRNAs during pregnancy

Yoichi Ishida, Dongwei Zhao, Akihide Ohkuchi, Tomoyuki Kuwata, Hiroshi Yoshitake, Kazuya Yuge, Takami Takizawa, Shigeki Matsubara, Mitsuaki Suzuki, Shigeru Saito, Toshihiro Takizawa
Pages: 1511-1524
Published online on: 27 March 2015

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Article Open Access

Silencing of uncoupling protein 2 by small interfering RNA aggravates mitochondrial dysfunction in cardiomyocytes under septic conditions

Guilang Zheng, Juanjuan Lyu, Shu Liu, Jinda Huang, Cui Liu, Dan Xiang, Meiyan Xie, Qiyi Zeng
Pages: 1525-1536
Published online on: 09 April 2015

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Article Open Access

Ischemic preconditioning protects neurons from damage and maintains the immunoreactivity of kynurenic acid in the gerbil hippocampal CA1 region following transient cerebral ischemia

Jae-Chul Lee, Hyun-Jin Tae, Geum-Sil Cho, In Hye Kim, Ji Hyeon Ahn, Joon Ha Park, Bai Hui Chen, Jeong-Hwi Cho, Bich Na Shin, Jun Hwi Cho, Eun Joo Bae, Jinseu Park, Young-Myeong Kim, Soo Young Choi, Moo-Ho Won
Pages: 1537-1544
Published online on: 07 April 2015

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Article Open Access

GATA4 transgenic mice as an in vivo model of congenital heart disease

Hua Han, Yu Chen, Gang Liu, Zengqiang Han, Zhou Zhao, Yin Tang
Pages: 1545-1553
Published online on: 09 April 2015

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Article Open Access

Application of multiplex ligation-dependent probe amplification, and identification of a heterozygous Alu-associated deletion and a uniparental disomy of chromosome 1 in two patients with 3-hydroxy-3-methylglutaryl-CoA lyase deficiency

Yuka Aoyama, Toshiyuki Yamamoto, Naomi Sakaguchi, Mika Ishige, Toju Tanaka, Tomoko Ichihara, Katsuaki Ohara, Hiroko Kouzan, Yasutomi Kinosada, Toshiyuki Fukao
Pages: 1554-1560
Published online on: 14 April 2015

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Article Open Access

Activating transcription factor 3 is overexpressed in human glioma and its knockdown in glioblastoma cells causes growth inhibition both in vitro and in vivo

Siqi Ma, Changhe Pang, Laijun Song, Fuyou Guo, Hongwei Sun
Pages: 1561-1573
Published online on: 07 April 2015

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Article Open Access

Changes in Dpysl2 expression are associated with prenatally stressed rat offspring and susceptibility to schizophrenia in humans

Hwayoung Lee, Jaesoon Joo, Seong-Su Nah, Jong Woo Kim, Hyung-Ki Kim, Jun-Tack Kwon, Hwa-Young Lee, Young Ock Kim, Hak-Jae Kim
Pages: 1574-1586
Published online on: 01 April 2015

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Article Open Access

miR‑204-5p promotes the adipogenic differentiation of human adipose-derived mesenchymal stem cells by modulating DVL3 expression and suppressing Wnt/β-catenin signaling

Honghui He, Ke Chen, Fang Wang, Liling Zhao, Xinxing Wan, Linghao Wang, Zhaohui Mo
Pages: 1587-1595
Published online on: 31 March 2015

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Article Open Access

Epigenetic repression of Krüppel-like factor 4 through Dnmt1 contributes to EMT in renal fibrosis

Xiangcheng Xiao, Wenbin Tang, Qiongjing Yuan, Ling Peng, Pingping Yu
Pages: 1596-1602
Published online on: 20 April 2015

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Article

Human neutrophil peptides induce interleukin-8 in intestinal epithelial cells through the P2 receptor and ERK1/2 signaling pathways

Kazunari Ibusuki, Toshio Sakiyama, Shuji Kanmura, Takuro Maeda, Yuji Iwashita, Yuichiro Nasu, Fumisato Sasaki, Hiroki Taguchi, Shinichi Hashimoto, Masatsugu Numata, Hirofumi Uto, Hirohito Tsubouchi, Akio Ido
Pages: 1603-1609
Published online on: 26 March 2015

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Article

Curcumin induces the apoptosis of non-small cell lung cancer cells through a calcium signaling pathway

Xudong Xu, Da Chen, Bo Ye, Fangming Zhong, Gang Chen
Pages: 1610-1616
Published online on: 02 April 2015

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Article

Combination of 12-O-tetradecanoylphorbol-13-acetate with diethyldithiocarbamate markedly inhibits pancreatic cancer cell growth in 3D culture and in immunodeficient mice

Huarong Huang, Kajia Cao, Saquib Malik, Qiuyan Zhang, Dongli Li, Richard Chang, Huaqian Wang, Weiping Lin, Jeremiah Van Doren, Kun Zhang, Zhiyun Du, Xi Zheng
Pages: 1617-1624
Published online on: 01 April 2015

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Article

Ischemic preconditioning increases GSK-3β/β-catenin levels and ameliorates liver ischemia/reperfusion injury in rats

Yichao Yan, Guangying Li, Xiaofeng Tian, Yingjiang Ye, Zhidong Gao, Jihong Yao, Feng Zhang, Shan Wang
Pages: 1625-1632
Published online on: 23 March 2015

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Article

NLRP3 inflammasome is responsible for Hantavirus inducing interleukin-1β in THP-1 cells Corrigendum in /10.3892/ijmm.2019.4155

Wei Ye, Yingfeng Lei, Mengmeng Yu, Yongni Xu, Mengyuan Cao, Lan Yu, Liang Zhang, Puyuan Li, Wentao Bai, Zhikai Xu, Fanglin Zhang
Pages: 1633-1640
Published online on: 01 April 2015

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Article

Hedgehog signaling is involved in the BMP9-induced osteogenic differentiation of mesenchymal stem cells Retraction in /10.3892/ijmm.2023.5233

Li Li, Qian Dong, Yufeng Wang, Qiaoling Feng, Pengfei Zhou, Xinying Ou, Qiurong Meng, Tongchuan He, Jinyong Luo
Pages: 1641-1650
Published online on: 07 April 2015

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Article

Effects of bee venom against Propionibacterium acnes‑induced inflammation in human keratinocytes and monocytes

Jung-Yeon Kim, Woo-Ram Lee, Kyung-Hyun Kim, Hyun-Jin An, Young-Chae Chang, Sang-Mi Han, Yoon-Yub Park, Sok Cheon Pak, Kwan-Kyu Park
Pages: 1651-1656
Published online on: 09 April 2015

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Article

Hydrogen sulfide attenuates IL-1β-induced inflammatory signaling and dysfunction of osteoarthritic chondrocytes

Chengzhi Ha, Shaoqi Tian, Kang Sun, Dawei Wang, Jiangtao Lv, Yuanhe Wang
Pages: 1657-1666
Published online on: 14 April 2015

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Article

AST Ⅳ inhibits H2O2-induced human umbilical vein endothelial cell apoptosis by suppressing Nox4 expression through the TGF-β1/Smad2 pathway

Yuhong Ma, Weizu Li, Yanyan Yin, Weiping Li
Pages: 1667-1674
Published online on: 17 April 2015

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Article

MAGE-A expression clusters and antineoplastic treatment in head and neck cancer

Stefan Hartmann, Till J. Meyer, Roman C. Brands, Imme R. Haubitz, Christian Linz, Axel Seher, Alexander C. Kübler, Urs D.A. Müller-Richter
Pages: 1675-1682
Published online on: 07 April 2015

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Article

LSm1 binds to the Dengue virus RNA 3' UTR and is a positive regulator of Dengue virus replication

Yangchao Dong, Jing Yang, Wei Ye, Yuan Wang, Yunbo Miao, Tianbing Ding, Chen Xiang, Yingfeng Lei, Zhikai Xu
Pages: 1683-1689
Published online on: 07 April 2015

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Article

Anti-inflammatory potential of saponins derived from cultured wild ginseng roots in lipopolysaccharide-stimulated RAW 264.7 macrophages

Gyeong-Jin Yu, Il-Whan Choi, Gi-Young Kim, Byung-Woo Kim, Cheol Park, Su-Hyun Hong, Sung-Kwon Moon, Hee-Jae Cha, Young-Chae Chang, Kee Yoeup Paek, Wun-Jae Kim, Yung Hyun Choi
Pages: 1690-1698
Published online on: 02 April 2015

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Article

Protective effects of Semen Crotonis Pulveratum on trinitrobenzene sulphonic acid-induced colitis in rats and H2O2-induced intestinal cell apoptosis in vitro

Xiaohong Wang, Jie Zhao, Zhe Han, Fang Tang
Pages: 1699-1707
Published online on: 07 April 2015

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Article

MicroRNA-155 modulates the proliferation of vascular smooth muscle cells by targeting endothelial nitric oxide synthase

Jun Zhang, Fei Zhao, Xiaoling Yu, Xiang Lu, Guofeng Zheng
Pages: 1708-1714
Published online on: 14 April 2015

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Article

Production of DUSP1 protein using the baculovirus insect cell expression system and its in vitro effects on cancer cells

Peng Cheng, Shuying Zhu, Li Jun, Lihua Huang, Yahui Hong
Pages: 1715-1719
Published online on: 09 April 2015

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Article

Influence of particle size on the in vitro and in vivo anti-inflammatory and anti-allergic activities of a curcumin lipid nanoemulsion

Takefumi Onodera, Isoko Kuriyama, Tooru Andoh, Hideki Ichikawa, Yuka Sakamoto, Eibai Lee-Hiraiwa, Yoshiyuki Mizushina
Pages: 1720-1728
Published online on: 16 April 2015

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Article

Interleukin-32 stimulates osteosarcoma cell invasion and motility via AKT pathway-mediated MMP-13 expression

Yanhong Zhou, Zhaohui Hu, Ningning Li, Renjie Jiang
Pages: 1729-1733
Published online on: 31 March 2015

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Article

Metformin attenuates palmitic acid-induced insulin resistance in L6 cells through the AMP-activated protein kinase/sterol regulatory element-binding protein-1c pathway

Wenjun Wu, Sunyinyan Tang, Junfeng Shi, Wenwen Yin, Shu Cao, Ruifang Bu, Dalong Zhu, Yan Bi
Pages: 1734-1740
Published online on: 17 April 2015

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Article

Hydrogen sulfide attenuates cytokine production through the modulation of chromatin remodeling

Ester C.S. Rios, Bartosz Szczesny, Francisco G. Soriano, Gabor Olah, Csaba Szabo
Pages: 1741-1746
Published online on: 08 April 2015

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Article

Effect of zinc on high glucose-induced epithelial-to-mesenchymal transition in renal tubular epithelial cells

Xiuli Zhang, Dan Liang, Zhi-Hong Chi, Qingqing Chu, Chenghai Zhao, Rong-Zheng Ma, Yue Zhao, Hongjuan Li
Pages: 1747-1754
Published online on: 07 April 2015

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Article

OSM is overexpressed in knee osteoarthritis and Notch signaling is involved in the effects of OSM on MC3T3-E1 cell proliferation and differentiation

J. Ni, X. M. Yuan, Q. Yao, L. B. Peng
Pages: 1755-1760
Published online on: 02 April 2015

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Article

Melia azedarach extract stimulates melanogenesis through increase of tyrosinase-related protein 1 expression in B16F10 mouse melanoma cells

Cheng Yao, Cheng Long Jin, Inn Gyung Oh, Chi-Hyun Park, Jin Ho Chung
Pages: 1761-1766
Published online on: 14 April 2015

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Article

Inhibition of farnesyl pyrophosphate synthase attenuates angiotensin II-induced fibrotic responses in vascular smooth muscle cells

Chang-Qing Du, Xiao-Wei Liu, Guang-Zhong Zeng, Hong-Feng Jin, Li-Jiang Tang
Pages: 1767-1772
Published online on: 02 April 2015

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Article

Suppressive effects of exogenous regucalcin on the proliferation of human pancreatic cancer MIA PaCa-2 cells in vitro

Masayoshi Yamaguchi, Tomiyasu Murata
Pages: 1773-1778
Published online on: 01 April 2015

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Article

Quercetin prevents adipogenesis by regulation of transcriptional factors and lipases in OP9 cells

Yun-Soo Seo, Ok-Hwa Kang, Sung-Bae Kim, Su-Hyun Mun, Da-Hye Kang, Da-Wun Yang, Jang-Gi Choi, Young-Mi Lee, Dae-Kil Kang, Ho-Seog Lee, Dong-Yeul Kwon
Pages: 1779-1785
Published online on: 15 April 2015

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Journal Cover
July-2026 Volume 58 Issue 1

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Journal Metrics

Impact Factor: 5.8

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Sex differences in cardiovascular‑kidney‑metabolic syndrome: From pathogenesis to treatment response (Review)

Yanqin Fan, Hongtu Hu, Jing Cheng
Article Number: 202
Published online on: 27 May 2026

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Retraction Open Access

[Retracted] BAMBI inhibits inflammation through the activation of autophagy in experimental spinal cord injury

Yin Yang, Chunyang Guo, Bo Liao, Junjun Cao, Chen Liang, Xijing He
Article Number: 201
Published online on: 25 May 2026

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Article Open Access

Integrative transcriptomic analysis unveils FXR as a key regulator of intestinal stemness and inflammation in ulcerative colitis

Hao Lin, Xinran Cheng, Yangyang Ren, Yongmei Zhang, Weixu Chen, Qingyan Lu, Yiqing Tian
Article Number: 200
Published online on: 22 May 2026

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Article Open Access

Ginsenoside Rg3 potentiates cisplatin antitumor activity while mitigating nephrotoxicity through SIRT1‑mediated suppression of the NLRP3 inflammasome

Jinghui Zhai, Yueming Zhang, Jiawei Gong, Li Fu, Sixi Zhang
Article Number: 199
Published online on: 22 May 2026

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Article Open Access

Identification of diagnostic markers for diabetic kidney disease by weighted gene co‑expression network analysis and machine learning

Qiming Xu, Chunjing Xu, Ziyang Liu, Jianrao Lu, Jing Hu, Lin Liao
Article Number: 198
Published online on: 21 May 2026

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Article Open Access

CTRP3 alleviates neuropathic pain by improving mitochondrial biogenesis and mitochondrial unfolded protein response via spinal SIRT1 in rats

Tianzhu Liu, Longqing Zhang, Wei Mei
Article Number: 197
Published online on: 21 May 2026

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Correction Open Access

[Corrigendum] Activated Wnt signaling induces myofibroblast differentiation of mesenchymal stem cells, contributing to pulmonary fibrosis

Zhaorui Sun, Cong Wang, Chaowen Shi, Fangfang Sun, Xiaomeng Xu, Weiping Qian, Shinan Nie, Xiaodong Han
Article Number: 196
Published online on: 20 May 2026

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Article Open Access

Ganoderma lucidum polysaccharides improve liver metabolic disorders by modulating gut microbiota of ovariectomized mice

Xin Jin, Xuan Liu, Yun-Juan Wang, Zi-Li Lei, Yan-Hong Yang
Article Number: 195
Published online on: 20 May 2026

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Article Open Access

Endothelial NOX4‑driven oxidative stress inhibition reverses HtrA1 deficiency‑induced blood‑brain barrier disruption and cognitive impairment

Shi-Na Song, Jun-Ying Wu, Mao-Mei Song, Xiao-Feng Li, Jian-Ming Wang, Wen-Hui Jia, Chang-Xin Li, Sui-Yi Xu
Article Number: 194
Published online on: 19 May 2026

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Review Open Access

Bone‑origin repair in diabetic foot ulcers: Mechanisms of callus formation and endocrine effects in healing (Review)

Sen Chen, Xiaofei Cui
Article Number: 193
Published online on: 19 May 2026

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Review Open Access

Unraveling the molecular landscape of chronic radiation injury: From oxidative stress signaling to translational modeling (Review)

Zhenjun Xi, Xiaodong Li, Chunhui Yang, Li Wang, Jingxin Mao, Qianqian Liu, Chang Liu, Qian Li, Yuanfang Hou, Jie Wan, Chengzhuo Yang, Feiji Sun, Chao Yu, Miao Wang, Baocheng Yuan, Yongsheng Liu, Qing Hu, Li Zhang, Xuemei Li, Xiaobing Li
Article Number: 192
Published online on: 19 May 2026

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Retraction Open Access

[Retracted] Cocktail therapy with a combination of interferon, ribavirin and angiotensin‑II type 1 receptor blocker attenuates murine liver fibrosis development

Hitoshi Yoshiji, Ryuichi Noguchi, Yasuhide Ikenaka, Kosuke Kaji, Yosuke Aihara, Yusaku Shirai, Junichi Yoshii, Koji Yanase, Hiroshi Fukui
Article Number: 191
Published online on: 18 May 2026

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Review Open Access

Autophagy and metabolic homeostasis: Exploration in obesity‑related metabolic diseases (Review)

Chenglin Lu, Xiangyu Qi, Yuting Tong, Peng Lu, Dandan Luo, Qingbo Guan, Chunxiao Yu
Article Number: 190
Published online on: 14 May 2026

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Review Open Access

Primary cilia dysfunction: A critical driver of metabolic diseases (Review)

Xiaojing Wang, Yi Jin, Kejia Xie, Pengfei Yao, Liguo Song, Hongdan Liu, Yanjie Tan
Article Number: 189
Published online on: 14 May 2026

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Review Open Access

Gut‑brain axis in anesthesia and critical illness: Molecular crosstalk and its impact on delirium and outcome (Review)

Xigang Ma, Yongsen Zhao
Article Number: 188
Published online on: 14 May 2026

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Article Open Access

Betulinic acid alleviates the inflammatory injury of osteoblasts in osteoporosis by augmenting autophagy via the AMPK-mTOR signaling pathway

Yiwei Zhao, Zechao Qu, Lin Liu, Yong Zhang, Xiaohao Wang, Bo Zhang, Yining Gong, Liang Yan
Article Number: 187
Published online on: 13 May 2026

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Correction Open Access

[Corrigendum] Induction of cardiomyocyte‑like cells from hair follicle cells in mice

Yong-Hee Kim, Bang-Jin Kim, Seok-Man Kim, Sun-Uk Kim, Buom-Yong Ryu
Article Number: 186
Published online on: 13 May 2026

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Review Open Access

Spatial hepatology: Decoding liver zonation for metabolic and regenerative therapeutics (Review)

Guiqing Chen, Hongyan Jia, Kai Zhao, Chang Gao, Yue Liu, Hong Zhu, Dakai Yang, Yun Cai
Article Number: 185
Published online on: 13 May 2026

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Article Open Access

Hepatic p38γ exacerbates acetaminophen‑induced acute liver injury via PI3K/Akt‑dependent mechanisms

Hui Fang, Min Shu, Jiaju Wang, Heng Tian, Jianguo Zhang, Ying Hu, He Li, Huan Zhou, Kangsheng Gu, Zhenhua Ren
Article Number: 184
Published online on: 12 May 2026

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Review Open Access

Pharmacological activity, molecular mechanisms and therapeutic potential of erianin (Review)

Chengyi Ming, Ni Zhu, You Yu, Hong Zhou, Meichun Hu
Article Number: 183
Published online on: 12 May 2026

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Review Open Access

Rab27: Molecular switch of tumor exosome secretion (Review)

Mengtian Tang, Zhongjian Zhu, Huaxin Duan, Shiming Tan, Mengzhou Shen, Xianjie Jiang, Qiu Peng, Linda Oyang, Zongyao Ren, Yujuan Zhou, Qianjin Liao
Article Number: 182
Published online on: 12 May 2026

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Article Open Access

IL‑17A+ γδT cell activation via the HMGB1‑TLR2/4‑NF‑κB signaling pathways in biliary atresia

Meng-Xin Zhang, Jing-Feng Tang, Mei Hong, Ying Yang, Yun Zhou, Shui-Qing Chi, Li-Ying Rong, Guo-Qing Cao, Xi Zhang, Jin-Xiang Zhang, Shao-Tao Tang
Article Number: 181
Published online on: 11 May 2026

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Article Open Access

CircRAD18 promotes glioblastoma proliferation, migration and invasion via the miR‑1231/LUC7L2 axis

Lumeng Song, Ping Xiong, Amu Jike, Xiaochao Xia, Lifang Mao, Zihao Wang, Yinchuan Cheng, Shumin Wang, Shizheng Tan, Dongnan Yu, Zheng Li, Xiaoping Tang, Shun Li
Article Number: 180
Published online on: 11 May 2026

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Correction Open Access

[Corrigendum] Expression of FKBP52 in the ovaries of PCOS rats

Shiyan Song, Yong Tan
Article Number: 179
Published online on: 11 May 2026

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Article Open Access

miR‑223‑3p promotes microglial lactylation and M1 polarization via the FBXW7/Notch1/Hes1/SIRT1 axis

Xiaoyu Wang, Lin Song, Jiafeng Wang, Qianqian Xie, Yan Wang, Chunyan Li, Tianqi Wang, Yifeng Du
Article Number: 178
Published online on: 08 May 2026

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Review Open Access

Radiotherapy and cytokines: A systems view of immunotherapy and toxicity (Review)

Siyuan Zhou, Yurong Jiang, Jixu Fan, Minjie Guo, Yi Wen, Chunhua Dai
Article Number: 177
Published online on: 08 May 2026

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Review Open Access

Advances in understanding the NLRP3 inflammasome‑mediated mechanisms and therapeutic targets in diabetic nephropathy (Review)

Xiwei Wang, Shuang Li, Xiaotian Ge, Tao Xie, Sainan Li, Ruiqi Yuan, Tianxi Li, Hui Yuan
Article Number: 176
Published online on: 06 May 2026

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Expression of Concern Open Access

[Expression of Concern] ISL1 promotes cancer progression and inhibits cisplatin sensitivity in triple‑negative breast cancer cells

Yang Zhang, Lu Wang, Peng Gao, Zhiguo Sun, Ning Li, Yanqin Lu, Jianglun Shen, Jian Sun, Yiming Yang, Hao Dai, Haifeng Cai
Article Number: 175
Published online on: 06 May 2026

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Review Open Access

Phosphorylation beyond the plasma membrane: How secretory pathway kinases sculpt the cellular dialogue in cancer (Review)

Ziang Geng, Shu Guan, Shaoqi Du, Shuo Zhang, Jiaxin Hao, Siyuan Tian, Chen Zhu, Shaonan Du
Article Number: 174
Published online on: 06 May 2026

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Review Open Access

Ferroptosis in musculoskeletal disorders: Emerging mechanisms and therapeutic opportunities (Review)

Wenhui Gu, Haifeng Zhang, Lisha Ye, Fangming Liu, Ting Xu, Yinxian Yu, Guohua Wang
Article Number: 173
Published online on: 05 May 2026

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Retraction Open Access

[Retracted] Regulation of p38 MAPK phosphorylation inhibits chondrocyte apoptosis in response to heat stress or mechanical stress

Ken Takebe, Takayuki Nishiyama, Shinya Hayashi, Shingo Hashimoto, Takaaki Fujishiro, Noriyuki Kanzaki, Kohei Kawakita, Kenjiro Iwasa, Ryosuke Kuroda, Masahiro Kurosaka
Article Number: 172
Published online on: 04 May 2026

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Article Open Access

Dapagliflozin attenuates ferroptosis in diabetic nephropathy through activation of the Nrf2/HO‑1 signaling pathway

Hanshuang Liu, Xiaoxiao Zhang, Yubing Cui, Shengxi Xiong, Linjuan Huang, Min Li, Chen Shao, Xiaolei Hu
Article Number: 171
Published online on: 30 April 2026

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Article Open Access

Ligustroflavone protects against acute kidney injury by inhibiting ferroptosis via acting on GSK3β/NRF2 signaling

Jiayu Song, Long Wang, Yaru Wang, Jie Meng, Jingyi Sheng, Yongfeng Zhao, San Yan Xu, Juan Lei, Fangfang Cai, Yunwen Yang
Article Number: 170
Published online on: 30 April 2026

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Correction Open Access

[Corrigendum] Differential regulation of the biosynthesis of glucose transporters by the PI3‑K and MAPK pathways of insulin signaling by treatment with novel compounds from Liriope platyphylla

Yoen Kyung Lee, Ji Eun Kim, So Hee Nam, Jun Seo Goo, Sun Il Cho, Young Hwan Choi, Chang Jun Bae, Ong Min Woo, Jung Sik Cho, Dae Youn Hwang
Article Number: 169
Published online on: 28 April 2026

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August-2026 Volume 58 Issue 2

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Journal Metrics

Impact Factor: 5.8

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Plant‑derived natural products alleviate dexamethasone‑induced skeletal muscle atrophy by modulating FoxO (Review)

Wei Dai, Jiabin Wu, Xiaotong Ma, Mingyu Wu, Ke Li, Haoyang Gao, Wenhong Wang, Weihua Xiao
Article Number: 212
Published online on: 05 June 2026

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Review Open Access

Functional hydrogels in cardiovascular therapy: Design, applications and clinical challenges (Review)

Zheming Yang, Jiayin Li, Lingxiao Zhao, Dali Zhang, Chenghui Yan, Dan Liu, Yaling Han
Article Number: 211
Published online on: 04 June 2026

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Review Open Access

Experimental rodent models of cardiorenal syndrome types 3 and 4: Insights and clinical relevance (Review)

Stefanny M. Figueroa, Siyi Huang, Javier Reyes‑Osorio, Jean-Jacques Boffa, Cristián A. Amador, Christos E. Chadjichristos, Louis Boutin
Article Number: 210
Published online on: 04 June 2026

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Expression of Concern Open Access

[Expression of Concern] Novel insights into the role of HSP90 in cytoprotection of H2S against chemical hypoxia‑induced injury in H9c2  cardiac myocytes

Zhanli Yang, Chuntao Yang, Liangcan Xiao, Xinxue Liao, Aiping Lan, Xiuyu Wang, Ruixian Guo, Peixi Chen, Chengheng Hu, Jianqiang Feng
Article Number: 209
Published online on: 03 June 2026

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Article Open Access

Microbiota‑derived indole‑3‑propionic acid reprograms bone marrow stem cell fate via PPARγ suppression to rescue osteoporosis

Jinwu Bai, Ruideng Wang, Jixing Fan, Shilong Su, Gao Si, Qinyong You, Ao Sun, Daole Hu, Shan Gao, Yang Lv, Fang Zhou
Article Number: 208
Published online on: 03 June 2026

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Article Open Access

Lactate regulates osteoclastogenesis via H3k18la in osteoarthritis

Zhibo Fan, Qiyue Fu, Tao Sun, Yutong Zhong, Yuefan Ma, Jingwei Jian, Shuosheng Yuan, Shenghong Li, Xiaomei Xu
Article Number: 207
Published online on: 02 June 2026

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Retraction Open Access

[Retracted] miR‑215 promotes epithelial to mesenchymal transition and proliferation by regulating LEFTY2 in endometrial cancert

Xiaoxu Gao, Yan Cai, Ruifang An
Article Number: 206
Published online on: 02 June 2026

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Review

Multi‑scale experimental models for the study of angiogenesis (Review)

Qin Yu, Jiarui Hu, Shuangshuang Yuan, Jiexia Gan, Mao Luo, Jianbo Wu, Liqun Wang
Article Number: 205
Published online on: 28 May 2026

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Review Open Access

Targeting lactylation in hepatocellular carcinoma: Mechanistic insights and therapeutic opportunities (Review)

Lianting Chen, Feiqiong Gao, Qianru Mei, Yujie Li, Qun Cai, Xudong Feng
Article Number: 204
Published online on: 28 May 2026

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Article Open Access

Oxygen‑sensing histone demethylase KDM6A modulates chondrocyte‑to‑osteoblast transdifferentiation by activating the Wnt/β‑catenin pathway

Yi Rong, Hao Yu, Heng Yin, Shaoshuo Li, Jianwei Wang, Zhongyuan Shen, Xinxin Ding, Fanchen Bu, Tianyi Dai, Gean Wu, Zhen Hua
Article Number: 203
Published online on: 28 May 2026

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