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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
August-2019 Volume 44 Issue 2

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

O-GlcNAcylation in immunity and inflammation: An intricate system (Review)

Yu Li, Mingzheng Xie, Lili Men, Jianling Du
Pages: 363-374
Published online on: 11 June 2019

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Review Open Access

The association of female and male infertility with telomere length (Review)

Eleni Vasilopoulos, Persefoni Fragkiadaki, Charikleia Kalliora, Domniki Fragou, Anca Oana Docea, Elena Vakonaki, Dimitris Tsoukalas, Daniela Calina, Ana Maria Buga, George Georgiadis, Charalampos Mamoulakis, Antonios Makrigiannakis, Demetrios A. Spandidos, Aristidis Tsatsakis
Pages: 375-389
Published online on: 31 May 2019

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Article Open Access

Screening of differentially expressed genes and identification of NUF2 as a prognostic marker in breast cancer

Wenjie Xu, Yizhen Wang, Yanan Wang, Shanmei Lv, Xiuping Xu, Xuejun Dong
Pages: 390-404
Published online on: 11 June 2019

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Article Open Access

Hydroxysafflor Yellow A mitigated myocardial ischemia/reperfusion injury by inhibiting the activation of the JAK2/STAT1 pathway

Donglai Zhou, Tingting Ding, Bin Ni, Yunyan Jing, Shanxin Liu
Pages: 405-416
Published online on: 05 June 2019

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Article Open Access

Role of TXNIP/NLRP3 in sepsis-induced myocardial dysfunction

Chun Yang, Wan Xia, Xiaolin Liu, Jian Lin, Aiping Wu
Pages: 417-426
Published online on: 06 June 2019

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Article Open Access

HMGA2 regulates acute myeloid leukemia progression and sensitivity to daunorubicin via Wnt/β-catenin signaling

Shuo Yang, Yueli Gu, Genjie Wang, Qingzhu Hu, Shuxia Chen, Yong Wang, Mingfeng Zhao
Pages: 427-436
Published online on: 05 June 2019

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Article Open Access

Quinalizarin, a specific CK2 inhibitor, can reduce icotinib resistance in human lung adenocarcinoma cell lines

Ke Li, Fangzheng Zhou, Yu Zhou, Sheng Zhang, Qianwen Li, Zhenyu Li, Li Liu, Gang Wu, Rui Meng
Pages: 437-446
Published online on: 30 May 2019

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Article Open Access

Effects of transcription factor EB on oxidative stress and apoptosis induced by high glucose in podocytes

Yingli Kang, Ying Li, Tao Zhang, Yanqing Chi, Maodong Liu
Pages: 447-456
Published online on: 24 May 2019

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Article Open Access

Protective effects of salvianolic acid B against hydrogen peroxide‑induced apoptosis of human umbilical vein endothelial cells and underlying mechanisms

Shan Gao, Shiqin Li, Qin Li, Fuyong Zhang, Mengqi Sun, Zilin Wan, Shurong Wang
Pages: 457-468
Published online on: 31 May 2019

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Article Open Access

Erythropoietin suppresses hepatic steatosis and obesity by inhibiting endoplasmic reticulum stress and upregulating fibroblast growth factor 21

Ting Hong, Zhijuan Ge, Bingjie Zhang, Ran Meng, Dalong Zhu, Yan Bi
Pages: 469-478
Published online on: 28 May 2019

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Article Open Access

Sevoflurane alleviates LPS‑induced acute lung injury via the microRNA‑27a‑3p/TLR4/MyD88/NF‑κB signaling pathway

Yunfei Wang, Xiaoran Zhang, Jianmin Tian, Guoze Liu, Xiaofang Li, Dan Shen
Pages: 479-490
Published online on: 30 May 2019

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Article Open Access

Rap1 regulates hepatic stellate cell migration through the modulation of RhoA activity in response to TGF‑β1

Mi‑Young Moon, Hee‑Jun Kim, Mo‑Jong Kim, Sunho Uhm, Ji‑Won Park, Ki‑Tae Suk, Jae‑Bong Park, Dong‑Jun Kim, Sung‑Eun Kim
Pages: 491-502
Published online on: 30 May 2019

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Article Open Access

Tetramethylpyrazine protects retinal ganglion cells against H2O2‑induced damage via the microRNA‑182/mitochondrial pathway

Xinmin Li, Qiuli Wang, Yanfan Ren, Xiaomin Wang, Huaxu Cheng, Hua Yang, Baojun Wang
Pages: 503-512
Published online on: 29 May 2019

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Article Open Access

Molecular characterization of alterations in the intestinal microbiota of patients with grade 3 hypertension

Nosheen Mushtaq, Safdar Hussain, Siruo Zhang, Lu Yuan, Huan Li, Shakir Ullah, Yan Wang, Jiru Xu
Pages: 513-522
Published online on: 06 June 2019

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Article Open Access

T7 peptide cytotoxicity in human hepatocellular carcinoma cells is mediated by suppression of autophagy

Feng Liu, Fuhai Wang, Xiaofeng Dong, Peng Xiu, Pengfei Sun, Zhongchao Li, Xuetao Shi, Jingtao Zhong
Pages: 523-534
Published online on: 06 June 2019

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Article Open Access

Investigating the regulatory role of ORMDL3 in airway barrier dysfunction using in vivo and in vitro models

Ruixue Yang, Min Tan, Jianya Xu, Xia Zhao
Pages: 535-548
Published online on: 06 June 2019

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Article Open Access

Exogenous H2S mitigates myocardial fibrosis in diabetic rats through suppression of the canonical Wnt pathway

Rui Yang, Qiang Jia, Shan‑Feng Ma, Ya Wang, Shomaila Mehmood, Yan Chen
Pages: 549-558
Published online on: 10 June 2019

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Article Open Access

Anti‑photoaging effect of fermented agricultural by‑products on ultraviolet B‑irradiated hairless mouse skin

Sun‑Il Choi, Tae‑Dong Jung, Bong‑Yeon Cho, Seung‑Hyun Choi, Wan‑Sup Sim, Xionggao Han, Sang Jong Lee, Young‑Cheul Kim, Ok‑Hwan Lee
Pages: 559-568
Published online on: 12 June 2019

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Article Open Access

MicroRNA-141 ameliorates alcoholic hepatitis‑induced intestinal injury and intestinal endotoxemia partially via a TLR4-dependent mechanism

Wei‑He Qian, Yuan‑Yuan Liu, Xiang Li, Yan Pan
Pages: 569-581
Published online on: 30 May 2019

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Article Open Access

Zoledronic acid inhibits osteoclast differentiation and function through the regulation of NF-κB and JNK signalling pathways

Xiao‑Lin Huang, Lie‑Yu Huang, Yu‑Ting Cheng, Fang Li, Qian Zhou, Chao Wu, Qian‑Hui Shi, Zhi‑Zhong Guan, Jian Liao, Wei Hong
Pages: 582-592
Published online on: 23 May 2019

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Article Open Access

miR‑381 functions as a tumor suppressor by targeting ETS1 in pancreatic cancer Retraction in /10.3892/ijmm.2025.5702

Guanen Qiao, Jing Li, Jun Wang, Zhaoyang Wang, Wei Bian
Pages: 593-607
Published online on: 23 May 2019

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Article Open Access

A microRNA‑24‑to‑secretagogin regulatory pathway mediates cholesterol‑induced inhibition of insulin secretion

Jing Yang, Yuncheng Lv, Zhibo Zhao, Wu Li, Sunmin Xiang, Lingzhi Zhou, Anbo Gao, Bin Yan, Lingling Ou, Hong Ling, Xinhua Xiao, Jianghua Liu
Pages: 608-616
Published online on: 31 May 2019

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Article Open Access

Classical dendritic cells regulate acute lung inflammation and injury in mice with lipopolysaccharide‑induced acute respiratory distress syndrome

Lang Li, Liang Dong, Dan Zhao, Fei Gao, Jie Yan
Pages: 617-629
Published online on: 23 May 2019

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Article Open Access

Long non-coding RNA XIST promotes extracellular matrix degradation by functioning as a competing endogenous RNA of miR-1277-5p in osteoarthritis

Tao Wang, Yize Liu, Yong Wang, Xuyang Huang, Wei Zhao, Zhonghai Zhao
Pages: 630-642
Published online on: 12 June 2019

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Article Open Access

Effects of miR‑340 overexpression and knockdown on the proliferation and metastasis of NSCLC cell lines Corrigendum in /10.3892/ijmm.2024.5433

Xidan Zhu, Gang Tian, Jing Quan, Peng He, Jinbo Liu
Pages: 643-651
Published online on: 29 May 2019

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Article Open Access

Strontium promotes osteogenic differentiation by activating autophagy via the the AMPK/mTOR signaling pathway in MC3T3‑E1 cells

You Cheng, Lunhui Huang, Yichao Wang, Qianyu Huo, Yanhong Shao, Huijing Bao, Zhaoyang Li, Yunde Liu, Xue Li
Pages: 652-660
Published online on: 30 May 2019

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Article Open Access

Botulinum toxin type A prevents the phenotypic transformation of fibroblasts induced by TGF‑β1 via the PTEN/PI3K/Akt signaling pathway

Xue Zhang, Dong Lan, Shuhua Ning, Hongxia Jia, Sisi Yu
Pages: 661-671
Published online on: 31 May 2019

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Article Open Access

Curcumin‑loaded PEG‑PDLLA nanoparticles for attenuating palmitate‑induced oxidative stress and cardiomyocyte apoptosis through AMPK pathway

Jingyi Zhang, Ying Wang, Cuiyu Bao, Tao Liu, Shuai Li, Jiaxi Huang, Ying Wan, Jing Li
Pages: 672-682
Published online on: 05 June 2019

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Article Open Access

Celecoxib inhibits the epithelial-to-mesenchymal transition in bladder cancer via the miRNA-145/TGFBR2/Smad3 axis Corrigendum in /10.3892/ijmm.2023.5267

Xiaoqiang Liu, Yanlong Wu, Zhengtao Zhou, Mingchuan Huang, Wen Deng, Yibing Wang, Xiaochen Zhou, Luyao Chen, Yu Li, Tao Zeng, Gongxian Wang, Bin Fu
Pages: 683-693
Published online on: 12 June 2019

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Article

miR‑128 is upregulated in epilepsy and promotes apoptosis through the SIRT1 cascade

De‑Zhe Chen, Wei‑Wei Wang, Yan‑Ling Chen, Xia‑Feng Yang, Min Zhao, Yan‑Yan Yang
Pages: 694-704
Published online on: 30 May 2019

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Article

Excess fructose and fatty acids trigger a model of non‑alcoholic fatty liver disease progression in vitro: Protective effect of the flavonoid silybin

Elena Grasselli, Francesca Baldini, Giulia Vecchione, Paulo J. Oliveira, Vilma A. Sardão, Adriana Voci, Piero Portincasa, Laura Vergani
Pages: 705-712
Published online on: 06 June 2019

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Article

Structural characterization and immune regulation of a novel polysaccharide from Maerkang Lactarius deliciosus Gray

Siyuan Su, Xiang Ding, Lei Fu, Yiling Hou
Pages: 713-724
Published online on: 30 May 2019

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Article

Protective effect of nicorandil on collapse‑induced lung injury in rabbits by inhibiting apoptosis

Chunguang Wang, Honggang Ke, Xingguo Xu, Junjie Chen, Dongyun Sun, Fuhai Ji
Pages: 725-736
Published online on: 06 June 2019

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Article

Resveratrol‑loaded nanoparticles inhibit enterovirus 71 replication through the oxidative stress‑mediated ERS/autophagy pathway

Na Du, Xiao‑Hua Li, Wan‑Guo Bao, Bin Wang, Guang Xu, Feng Wang
Pages: 737-749
Published online on: 28 May 2019

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Article

Autophagy protects nucleus pulposus cells from cyclic mechanical tension‑induced apoptosis

Minghui Yang, Chencheng Feng, Yang Zhang, Chang Liu, Bin Li, Qi Zhu, Bo Huang, Yue Zhou
Pages: 750-758
Published online on: 28 May 2019

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Article

Enterovirus 71 VP1 promotes mouse Schwann cell autophagy via ER stress‑mediated PMP22 upregulation

Peiqing Li, Sida Yang, Dandan Hu, Dan Wei, Jing Lu, Huanying Zheng, Shushan Nie, Guangming Liu, Haomei Yang
Pages: 759-767
Published online on: 30 May 2019

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Correction Open Access

[Corrigendum] Analysis of a nanoparticle‑enriched fraction of plasma reveals miRNA candidates for Down syndrome pathogenesis

Alessandro Salvi, Marika Vezzoli, Sara Busatto, Lucia Paolini, Teresa Faranda, Edoardo Abeni, Maria Caracausi, Francesca Antonaros, Allison Piovesan, Chiara Locatelli, Guido Cocchi, Gualtiero Alvisi, Giuseppina De Petro, Doris Ricotta, Paolo Bergese, Annalisa Radeghieri
Pages: 768-768
Published online on: 30 May 2019

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Journal Cover
January-2026 Volume 57 Issue 1

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

FK506‑binding proteins as emerging bridges linking proteostasis to multi‑system pathogenesis and therapeutic strategies (Review)

Zhi Li, Xiaolei Liu, Hesong Zeng
Article Number: 30
Published online on: 24 November 2025

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Retraction Open Access

[Retracted] Suppression of SIK1 by miR‑141 in human ovarian cancer cell lines and tissues

Jin-Long Chen, Fang Chen, Ting-Ting Zhang, Nai-Fu Liu
Article Number: 29
Published online on: 24 November 2025

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Article Open Access

METTL3 inhibits LINC00312 to suppress osteoporosis progression in a YTHDF2‑dependent manner

Yang Wang, Yihao Tian, Gang Yao
Article Number: 28
Published online on: 20 November 2025

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Review Open Access

Decoding structural birth defects through genomic landscapes: Innovative frameworks for diagnosis (Review)

Ruihao Xu, Haoming Ren, Zhengwei Yuan, Wanqi Huang, Hui Gu
Article Number: 27
Published online on: 20 November 2025

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Article Open Access

MOTS‑c protects against placental injury via Nrf2 activation in hypoxia‑induced intrauterine growth restriction mice

Dan Chen, Hui-Min Zhao, Xiao-Lin Sun, Zhi-Xuan Xing, Sheng-Peng Li, Shuai-Chao Li, Ya-Xian Wu, Qing-Feng Pang, Jian-Feng Huang
Article Number: 26
Published online on: 18 November 2025

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Article Open Access

Synergistic effects of Akebia saponin D and Semaglutide on diabetic nephropathy and osteoporosis via the Klotho‑p53 signaling axis

Qian Zhang, Dan Wang, Hongxia Jia, Zongji Zheng, Liyan Lin, Linna Li, Ling Wang, Yaoming Xue
Article Number: 25
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑103 modulates tumor progression by targeting KLF7 in non‑small cell lung cancer

Ke Li, Conghu Yuan
Article Number: 24
Published online on: 17 November 2025

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Article

Comparative analysis of pan MHC‑I epitopes immunoreactivity on Hantaan virus nucleocapsid protein

Zhikui Li, Weijie Ding, Yubo Sun, Chenfeng Tian, Shuaishuai Fu, Fei Shi, Zhenchi Fang, Yuanzhe Li, Jianchang Li, Sirui Cai, Haobo Kang, Baozeng Sun, Junqi Zhang, Yuanjie Sun, Shuya Yang, Yusi Zhang, Chunmei Zhang, Yun Zhang, Xiyang Zhang, Kun Yang, Dongbo Jiang
Article Number: 23
Published online on: 14 November 2025

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Article Open Access

Human papillomavirus E7 inhibits immune responses in keratinocytes by activating HTRA1‑mediated mitophagy

Boya Zhang, Defeng Kong, Siji Chen, Xuewu Sun, Hao Cheng
Article Number: 22
Published online on: 14 November 2025

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Article Open Access

Targeting p38 MAPK signaling pathway: 
Quercetin as a novel therapy for TMJ synovitis

Mosha Cheng, Yuhe Guan, Xiaotao Xin, Xin Yi, Yi Liu
Article Number: 21
Published online on: 13 November 2025

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Review Open Access

Lipid droplets in astrocytes: Key organelles for CNS homeostasis and disease (Review)

Yuchen Wang, Boxuan Wang, Jinchao Hou, Xiaodong Huo, Chenlin Liu, Ruili Guan, Honggang Chen, Yang Zhou, Jianbin Zhang, Congcong Zhuang, Yuankang Zou
Article Number: 20
Published online on: 13 November 2025

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Review Open Access

Copper dyshomeostasis and cardiovascular disease: Molecular mechanisms and new strategies for targeted intervention with cuproptosis (Review)

Peiyu Li, Yinghui Li, Qian Meng, Jie Wang, Kun Wang, Sumin Yang
Article Number: 19
Published online on: 13 November 2025

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Article Open Access

Elevated FTO alleviates sepsis‑induced acute kidney injury by regulating macrophage inflammatory phenotypes

Xiaona Chen, Ziqi Sun, Jiabo Chen, Jinquan Zhang, Zeyu Liu, Zhengzheng Yan, Quan Li, Zhixia Chen
Article Number: 18
Published online on: 12 November 2025

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Correction Open Access

[Corrigendum]  Suppression of PAX6 promotes cell proliferation and inhibits apoptosis in human retinoblastoma cells

Bo Meng, Yisong Wang, Bin Li
Article Number: 17
Published online on: 10 November 2025

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Review Open Access

Microbial short chain fatty acids: Effective histone deacetylase inhibitors in immune regulation (Review)

Jing Wang, Qin Zhao, Shuwan Zhang, Jia Liu, Xingyue Fan, Bin Han, Yaqin Hou, Xiaopeng Ai
Article Number: 16
Published online on: 05 November 2025

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Review Open Access

High‑fat diet and cognitive dysfunction: Mechanistic insights into diet‑induced neurodegeneration (Review)

Min You, Fan Wu, Feng Xiong, Xue-Fei Hu, Huan Wu, Li Zhou, Hong-Xing Zhang
Article Number: 15
Published online on: 05 November 2025

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Article Open Access

ROCK inhibition promotes axon and myelin regeneration via PI3K/Akt/GSK3β in a mouse sciatic nerve injury model

Shuang Dou, Zhijun Li, Boyao Zheng, Zhenyu Ren, Hai Wang, Qing Zuo, Fang Fang, Yuehong Zhuang
Article Number: 14
Published online on: 05 November 2025

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Review Open Access

Mechanisms of mTORC1 and GCN2 amino acid sensing pathways in tumorigenesis and metastatic progression (Review)

Chaowei Zhang, Yuxuan Han, Weiyi Yao, Qing Hong, Na Chen
Article Number: 13
Published online on: 04 November 2025

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Review Open Access

β‑hydroxybutyric acid as a potential therapeutic metabolite for type 2 diabetes mellitus (Review)

Xianyi Ding, Jiabin Wu, Lian Wang, Ke Li, Haoyang Gao, Mingyu Wu, Qiuyu Zhang, Ruonan Han, Wenhong Wang, Weihua Xiao
Article Number: 12
Published online on: 03 November 2025

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Review

Histone lactylation: Unveiling a novel pathway for the impact of lactate on physiological and pathological processes (Review)

Xunjie Jian, Chang Cheng, Wenjie Lu, Hui Peng, Diqi Yang
Article Number: 11
Published online on: 03 November 2025

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Review Open Access

Interpretation of the molecular mechanism and therapeutic potential of microRNA‑155 in cardiovascular and cerebrovascular diseases (Review)

Xitong Zhao, Pengqin Wang
Article Number: 10
Published online on: 03 November 2025

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Expression of Concern Open Access

[Expression of Concern]  CDKN2A (p16INK4A) affects the anti‑tumor effect of CDK inhibitor in somatotroph adenomas

Yiyuan Chen, Zhenye Li, Qiuyue Fang, Hongyun Wang, Chuzhong Li, Hua Gao, Yazhuo Zhang
Article Number: 9
Published online on: 29 October 2025

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Article Open Access

TWEAK modulates the characteristics of periodontal ligament stem cells via the Fn14/NF‑κB pathway

Linlin Xiao, Man Qu, Lulu Chen, Mingli Xiang, Qian Long, Jianguo Liu, Xiaoyan Guan, Chengcheng Liao
Article Number: 8
Published online on: 27 October 2025

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Harnessing copper: Innovative approaches to combat neurodegenerative diseases and cancer (Review)

Tao Duan, Hanhai Mao, Xingyue Jiang, Ying Tian, Jidong Zhang, Jun Tan
Article Number: 7
Published online on: 27 October 2025

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Retraction Open Access

[Retracted] Effects of miR‑106b‑3p on cell proliferation and epithelial‑mesenchymal transition, and targeting of ZNRF3 in esophageal squamous cell carcinoma

Guanen Qiao, Chenguang Dai, Yang He, Junjie Shi, Chunfang Xu
Article Number: 6
Published online on: 27 October 2025

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Immune and metabolic remodeling following bariatric surgery: Implications for targeted immunotherapy (Review)

Yiming Shao, Ke Song, Ruixin Yu, He Xiao, Chengjun Li, Yuling Deng, Yuan Zhang, Yixing Ren
Article Number: 5
Published online on: 24 October 2025

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Article Open Access

Exportin 1 inhibitor KPT‑330 reverses oxaliplatin resistance via p53 nuclear retention in colorectal cancer

Chuanxi Lai, Xiya Jia, Yiyi Chen, Kangke Chen, Fei Wang, Qiqi Zhang, Xiaonan Xiang, Zhe-Sheng Chen, Lingna Xu, Sheng Dai
Article Number: 4
Published online on: 23 October 2025

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Targeting of CIRP attenuates osteoarthritis progression via suppressing TLR4/NF‑κB/NLRP3 signaling axis

Weichao Sun, Yi Liao, Jianguo Feng, Jianhui Liang, Qifei He, Yinxing Cui, Dixi Huang, Houyin Shi, Wei You, Wei Sun, Qian Yi
Article Number: 3
Published online on: 23 October 2025

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Review

Importance of B cells (Review)

Zhiyuan Liu, Haoran Dai, Xiaoyu Cui, Yeping Liu, Zhaocheng Dong
Article Number: 2
Published online on: 22 October 2025

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Retraction Open Access

[Retracted] Hypoxic preconditioned bone mesenchymal stem cells ameliorate spinal cord injury in rats via improved survival and migration

Weiheng Wang, Xiaodong Huang, Wenbo Lin, Yuanyuan Qiu, Yunfei He, Jiangming Yu, Yanhai Xi, Xiaojian Ye
Article Number: 1
Published online on: 22 October 2025

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February-2026 Volume 57 Issue 2

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

FGF4 alleviates the lung cell damage caused by high glucose via AMPK‑PGC‑1 signaling axis in vitro and in vivo

Qiujuan Fu, Yongfang Ou, Qin Wu, Jue Gong, Feixia Li, Tuxing Wang, Zhitai Lin, Kejie Huang, Jianlong Xie
Article Number: 39
Published online on: 05 December 2025

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STOML2 interacts with PHB to activate the MEK/ERK signaling pathway and mediates autophagy‑related proteins in the progression of hepatocellular carcinoma

Haoyang Hu, Haozhe Zhang, Shuai Han, Jianli Chen, Ying Xie
Article Number: 38
Published online on: 04 December 2025

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HMGB1 mediates low-dose ionizing radiation-induced Wnt/β-catenin activation in SRA01/04 cells: Mechanistic clues to early cataractogenesis

Ping Wang, Chunnan Piao, Dong Yan, Yingxue He, Yaru Li, Li Fan, Mei Tian
Article Number: 37
Published online on: 04 December 2025

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FBXO22 promotes hepatocellular carcinoma progression via paracrine myo‑inositol‑induced M2‑type polarization of macrophages

Liangliang Bai, Jing Xiong, Sihai Chen, Jiahao Hu, Meixia Zhang, Bimin Li, Jing Hu, Mingyan He
Article Number: 36
Published online on: 02 December 2025

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Branched‑chain amino acid metabolism and bone metabolism: Implications for osteoporosis pathogenesis and therapeutic strategies (Review)

Qi Xiao, Haimin Zeng, Ruhui Yang, Yuxin Zhan, Fangzhen Lin, Bofan Chen, Xiang Chen
Article Number: 35
Published online on: 02 December 2025

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Mitochondria-associated endoplasmic reticulum membranes: Emerging regulators of cardiac microvascular ischemia/reperfusion injury (Review)

Yan Wang, Baowei Feng, Yanting Wu, Zongle Sun, Hao Yuan, Wei Chen, Chang Zhao, Zhi Liu
Article Number: 34
Published online on: 02 December 2025

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Role of matrix metalloproteinases in the invasion of glioblastoma and drug interventions (Review)

Bohao Zheng, Ying Han, Haiying Zhang
Article Number: 33
Published online on: 01 December 2025

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Bridging bench to bedside: Exosome‑based strategies for endometriosis diagnosis and treatment (Review)

Wanmeng Chen, Yujiu Ma, Xudong Zhang, Siwen Zhang, Shanshan Wu, Yimeng Lu, Jichun Tan
Article Number: 32
Published online on: 01 December 2025

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Retraction Open Access

[Retracted] miR‑381 functions as a tumor suppressor by targeting ETS1 in pancreatic cancer

Guanen Qiao, Jing Li, Jun Wang, Zhaoyang Wang, Wei Bian
Article Number: 31
Published online on: 01 December 2025

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