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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
August-2019 Volume 44 Issue 2

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Journal Metrics

Impact Factor: 8.5

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

O-GlcNAcylation in immunity and inflammation: An intricate system (Review)

Yu Li, Mingzheng Xie, Lili Men, Jianling Du
Pages: 363-374
Published online on: 11 June 2019

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Review Open Access

The association of female and male infertility with telomere length (Review)

Eleni Vasilopoulos, Persefoni Fragkiadaki, Charikleia Kalliora, Domniki Fragou, Anca Oana Docea, Elena Vakonaki, Dimitris Tsoukalas, Daniela Calina, Ana Maria Buga, George Georgiadis, Charalampos Mamoulakis, Antonios Makrigiannakis, Demetrios A. Spandidos, Aristidis Tsatsakis
Pages: 375-389
Published online on: 31 May 2019

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Article Open Access

Screening of differentially expressed genes and identification of NUF2 as a prognostic marker in breast cancer

Wenjie Xu, Yizhen Wang, Yanan Wang, Shanmei Lv, Xiuping Xu, Xuejun Dong
Pages: 390-404
Published online on: 11 June 2019

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Article Open Access

Hydroxysafflor Yellow A mitigated myocardial ischemia/reperfusion injury by inhibiting the activation of the JAK2/STAT1 pathway

Donglai Zhou, Tingting Ding, Bin Ni, Yunyan Jing, Shanxin Liu
Pages: 405-416
Published online on: 05 June 2019

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Article Open Access

Role of TXNIP/NLRP3 in sepsis-induced myocardial dysfunction

Chun Yang, Wan Xia, Xiaolin Liu, Jian Lin, Aiping Wu
Pages: 417-426
Published online on: 06 June 2019

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Article Open Access

HMGA2 regulates acute myeloid leukemia progression and sensitivity to daunorubicin via Wnt/β-catenin signaling

Shuo Yang, Yueli Gu, Genjie Wang, Qingzhu Hu, Shuxia Chen, Yong Wang, Mingfeng Zhao
Pages: 427-436
Published online on: 05 June 2019

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Article Open Access

Quinalizarin, a specific CK2 inhibitor, can reduce icotinib resistance in human lung adenocarcinoma cell lines

Ke Li, Fangzheng Zhou, Yu Zhou, Sheng Zhang, Qianwen Li, Zhenyu Li, Li Liu, Gang Wu, Rui Meng
Pages: 437-446
Published online on: 30 May 2019

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Article Open Access

Effects of transcription factor EB on oxidative stress and apoptosis induced by high glucose in podocytes

Yingli Kang, Ying Li, Tao Zhang, Yanqing Chi, Maodong Liu
Pages: 447-456
Published online on: 24 May 2019

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Article Open Access

Protective effects of salvianolic acid B against hydrogen peroxide‑induced apoptosis of human umbilical vein endothelial cells and underlying mechanisms

Shan Gao, Shiqin Li, Qin Li, Fuyong Zhang, Mengqi Sun, Zilin Wan, Shurong Wang
Pages: 457-468
Published online on: 31 May 2019

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Article Open Access

Erythropoietin suppresses hepatic steatosis and obesity by inhibiting endoplasmic reticulum stress and upregulating fibroblast growth factor 21

Ting Hong, Zhijuan Ge, Bingjie Zhang, Ran Meng, Dalong Zhu, Yan Bi
Pages: 469-478
Published online on: 28 May 2019

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Article Open Access

Sevoflurane alleviates LPS‑induced acute lung injury via the microRNA‑27a‑3p/TLR4/MyD88/NF‑κB signaling pathway

Yunfei Wang, Xiaoran Zhang, Jianmin Tian, Guoze Liu, Xiaofang Li, Dan Shen
Pages: 479-490
Published online on: 30 May 2019

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Article Open Access

Rap1 regulates hepatic stellate cell migration through the modulation of RhoA activity in response to TGF‑β1

Mi‑Young Moon, Hee‑Jun Kim, Mo‑Jong Kim, Sunho Uhm, Ji‑Won Park, Ki‑Tae Suk, Jae‑Bong Park, Dong‑Jun Kim, Sung‑Eun Kim
Pages: 491-502
Published online on: 30 May 2019

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Article Open Access

Tetramethylpyrazine protects retinal ganglion cells against H2O2‑induced damage via the microRNA‑182/mitochondrial pathway

Xinmin Li, Qiuli Wang, Yanfan Ren, Xiaomin Wang, Huaxu Cheng, Hua Yang, Baojun Wang
Pages: 503-512
Published online on: 29 May 2019

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Article Open Access

Molecular characterization of alterations in the intestinal microbiota of patients with grade 3 hypertension

Nosheen Mushtaq, Safdar Hussain, Siruo Zhang, Lu Yuan, Huan Li, Shakir Ullah, Yan Wang, Jiru Xu
Pages: 513-522
Published online on: 06 June 2019

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Article Open Access

T7 peptide cytotoxicity in human hepatocellular carcinoma cells is mediated by suppression of autophagy

Feng Liu, Fuhai Wang, Xiaofeng Dong, Peng Xiu, Pengfei Sun, Zhongchao Li, Xuetao Shi, Jingtao Zhong
Pages: 523-534
Published online on: 06 June 2019

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Article Open Access

Investigating the regulatory role of ORMDL3 in airway barrier dysfunction using in vivo and in vitro models

Ruixue Yang, Min Tan, Jianya Xu, Xia Zhao
Pages: 535-548
Published online on: 06 June 2019

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Article Open Access

Exogenous H2S mitigates myocardial fibrosis in diabetic rats through suppression of the canonical Wnt pathway

Rui Yang, Qiang Jia, Shan‑Feng Ma, Ya Wang, Shomaila Mehmood, Yan Chen
Pages: 549-558
Published online on: 10 June 2019

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Article Open Access

Anti‑photoaging effect of fermented agricultural by‑products on ultraviolet B‑irradiated hairless mouse skin

Sun‑Il Choi, Tae‑Dong Jung, Bong‑Yeon Cho, Seung‑Hyun Choi, Wan‑Sup Sim, Xionggao Han, Sang Jong Lee, Young‑Cheul Kim, Ok‑Hwan Lee
Pages: 559-568
Published online on: 12 June 2019

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Article Open Access

MicroRNA-141 ameliorates alcoholic hepatitis‑induced intestinal injury and intestinal endotoxemia partially via a TLR4-dependent mechanism

Wei‑He Qian, Yuan‑Yuan Liu, Xiang Li, Yan Pan
Pages: 569-581
Published online on: 30 May 2019

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Article Open Access

Zoledronic acid inhibits osteoclast differentiation and function through the regulation of NF-κB and JNK signalling pathways

Xiao‑Lin Huang, Lie‑Yu Huang, Yu‑Ting Cheng, Fang Li, Qian Zhou, Chao Wu, Qian‑Hui Shi, Zhi‑Zhong Guan, Jian Liao, Wei Hong
Pages: 582-592
Published online on: 23 May 2019

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Article Open Access

miR‑381 functions as a tumor suppressor by targeting ETS1 in pancreatic cancer Retraction in /10.3892/ijmm.2025.5702

Guanen Qiao, Jing Li, Jun Wang, Zhaoyang Wang, Wei Bian
Pages: 593-607
Published online on: 23 May 2019

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Article Open Access

A microRNA‑24‑to‑secretagogin regulatory pathway mediates cholesterol‑induced inhibition of insulin secretion

Jing Yang, Yuncheng Lv, Zhibo Zhao, Wu Li, Sunmin Xiang, Lingzhi Zhou, Anbo Gao, Bin Yan, Lingling Ou, Hong Ling, Xinhua Xiao, Jianghua Liu
Pages: 608-616
Published online on: 31 May 2019

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Article Open Access

Classical dendritic cells regulate acute lung inflammation and injury in mice with lipopolysaccharide‑induced acute respiratory distress syndrome Retraction in /10.3892/ijmm.2026.5884

Lang Li, Liang Dong, Dan Zhao, Fei Gao, Jie Yan
Pages: 617-629
Published online on: 23 May 2019

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Article Open Access

Long non-coding RNA XIST promotes extracellular matrix degradation by functioning as a competing endogenous RNA of miR-1277-5p in osteoarthritis

Tao Wang, Yize Liu, Yong Wang, Xuyang Huang, Wei Zhao, Zhonghai Zhao
Pages: 630-642
Published online on: 12 June 2019

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Article Open Access

Effects of miR‑340 overexpression and knockdown on the proliferation and metastasis of NSCLC cell lines Corrigendum in /10.3892/ijmm.2024.5433

Xidan Zhu, Gang Tian, Jing Quan, Peng He, Jinbo Liu
Pages: 643-651
Published online on: 29 May 2019

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Article Open Access

Strontium promotes osteogenic differentiation by activating autophagy via the the AMPK/mTOR signaling pathway in MC3T3‑E1 cells

You Cheng, Lunhui Huang, Yichao Wang, Qianyu Huo, Yanhong Shao, Huijing Bao, Zhaoyang Li, Yunde Liu, Xue Li
Pages: 652-660
Published online on: 30 May 2019

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Article Open Access

Botulinum toxin type A prevents the phenotypic transformation of fibroblasts induced by TGF‑β1 via the PTEN/PI3K/Akt signaling pathway

Xue Zhang, Dong Lan, Shuhua Ning, Hongxia Jia, Sisi Yu
Pages: 661-671
Published online on: 31 May 2019

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Article Open Access

Curcumin‑loaded PEG‑PDLLA nanoparticles for attenuating palmitate‑induced oxidative stress and cardiomyocyte apoptosis through AMPK pathway

Jingyi Zhang, Ying Wang, Cuiyu Bao, Tao Liu, Shuai Li, Jiaxi Huang, Ying Wan, Jing Li
Pages: 672-682
Published online on: 05 June 2019

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Article Open Access

Celecoxib inhibits the epithelial-to-mesenchymal transition in bladder cancer via the miRNA-145/TGFBR2/Smad3 axis Corrigendum in /10.3892/ijmm.2023.5267

Xiaoqiang Liu, Yanlong Wu, Zhengtao Zhou, Mingchuan Huang, Wen Deng, Yibing Wang, Xiaochen Zhou, Luyao Chen, Yu Li, Tao Zeng, Gongxian Wang, Bin Fu
Pages: 683-693
Published online on: 12 June 2019

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Article

miR‑128 is upregulated in epilepsy and promotes apoptosis through the SIRT1 cascade

De‑Zhe Chen, Wei‑Wei Wang, Yan‑Ling Chen, Xia‑Feng Yang, Min Zhao, Yan‑Yan Yang
Pages: 694-704
Published online on: 30 May 2019

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Article

Excess fructose and fatty acids trigger a model of non‑alcoholic fatty liver disease progression in vitro: Protective effect of the flavonoid silybin

Elena Grasselli, Francesca Baldini, Giulia Vecchione, Paulo J. Oliveira, Vilma A. Sardão, Adriana Voci, Piero Portincasa, Laura Vergani
Pages: 705-712
Published online on: 06 June 2019

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Article

Structural characterization and immune regulation of a novel polysaccharide from Maerkang Lactarius deliciosus Gray

Siyuan Su, Xiang Ding, Lei Fu, Yiling Hou
Pages: 713-724
Published online on: 30 May 2019

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Article

Protective effect of nicorandil on collapse‑induced lung injury in rabbits by inhibiting apoptosis

Chunguang Wang, Honggang Ke, Xingguo Xu, Junjie Chen, Dongyun Sun, Fuhai Ji
Pages: 725-736
Published online on: 06 June 2019

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Article

Resveratrol‑loaded nanoparticles inhibit enterovirus 71 replication through the oxidative stress‑mediated ERS/autophagy pathway

Na Du, Xiao‑Hua Li, Wan‑Guo Bao, Bin Wang, Guang Xu, Feng Wang
Pages: 737-749
Published online on: 28 May 2019

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Article

Autophagy protects nucleus pulposus cells from cyclic mechanical tension‑induced apoptosis

Minghui Yang, Chencheng Feng, Yang Zhang, Chang Liu, Bin Li, Qi Zhu, Bo Huang, Yue Zhou
Pages: 750-758
Published online on: 28 May 2019

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Article

Enterovirus 71 VP1 promotes mouse Schwann cell autophagy via ER stress‑mediated PMP22 upregulation

Peiqing Li, Sida Yang, Dandan Hu, Dan Wei, Jing Lu, Huanying Zheng, Shushan Nie, Guangming Liu, Haomei Yang
Pages: 759-767
Published online on: 30 May 2019

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Correction Open Access

[Corrigendum] Analysis of a nanoparticle‑enriched fraction of plasma reveals miRNA candidates for Down syndrome pathogenesis

Alessandro Salvi, Marika Vezzoli, Sara Busatto, Lucia Paolini, Teresa Faranda, Edoardo Abeni, Maria Caracausi, Francesca Antonaros, Allison Piovesan, Chiara Locatelli, Guido Cocchi, Gualtiero Alvisi, Giuseppina De Petro, Doris Ricotta, Paolo Bergese, Annalisa Radeghieri
Pages: 768-768
Published online on: 30 May 2019

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Journal Cover
October-2026 Volume 58 Issue 4

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Journal Metrics

Impact Factor: 8.5

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Role of adipocytes and their derived extracellular vesicles in the progression, diagnosis and treatment of liver diseases (Review)

Kangrong Li, Muhammad Zubair, Yongmin Yan, Jiahao Xu
Article Number: 293
Published online on: 20 August 2026

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Correction Open Access

[Corrigendum] EBM84 attenuates airway inflammation and mucus hypersecretion in an ovalbumin‑induced murine model of asthma

In Sik Shin, Mee Young Lee, Woo Young Jeon, Na Ra Shin, Chang Seob Seo, Hyekyung Ha
Article Number: 292
Published online on: 20 August 2026

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Review Open Access

Decoding fibroblast activation: Transcriptional networks in hepatic stellate cells and across fibrotic organs (Review)

Denita Charoenthanakitkul, Chaiyaboot Ariyachet
Article Number: 291
Published online on: 20 August 2026

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Review Open Access

Inflammatory bowel disease treatment: Mechanisms to clinical translation (Review)

Siqi Tang, Guoyou Gou, Youjia Liu, Fang Wang, Feihong Shu, Ya Deng, Ting Zhang, Jingyu Xu, Rui Xie
Article Number: 290
Published online on: 18 August 2026

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Review Open Access

Redox biology in PCOS: Biomarkers, mechanistic networks, and targeted interventions (Review)

Yuena Qiu, Xiaojing Guo, Jie An
Article Number: 289
Published online on: 18 August 2026

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Review Open Access

Glucose metabolism in osteoporosis: A potential therapeutic target (Review)

Shengyao Peng, Zhuo Yao, Junzhe Guo, Chi Zhang, Keda Yang, Lin Tao
Article Number: 288
Published online on: 17 August 2026

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Retraction Open Access

[Retracted] Engulfment of platelets delays endothelial cell aging via girdin and its phosphorylation

Yong Lan, Yongjun Li, Dajun Li, Peng Li, Jiyang Wang, Yongpeng Diao, Guodong Ye, Yangfang Li
Article Number: 287
Published online on: 17 August 2026

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Article Open Access

α‑Cyperone targets the PAK1‑JNK/NF‑κB axis to modulate dendritic cells maturation and Th2/Th9 differentiation in an asthma model

Hang Hu, Xing Wang, Linlin Guo, Ziling Zeng, Hongmei Tang, Yun Zhang, Jiayao Duan, Kaijin Wang
Article Number: 286
Published online on: 14 August 2026

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Article Open Access

Early high‑frequency spinal cord stimulation modulates the ROS/p38 MAPK/NF‑κB and CXCL10/CXCR3 pathways to alleviate neuropathic pain and promote spinal cord injury repair

Sitong Su, Tao Liu, Honghui Lei, Yang Yu, Caizhi Ma, Xinglang Wang, Haoyuan Chen, Zebin Huang, Meiling Cheng, Tongtong Qian, Fangyong Wang
Article Number: 285
Published online on: 13 August 2026

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Review Open Access

Shared mechanisms of musculoskeletal dysfunction in type 2 diabetes mellitus: Insights into future therapeutic directions (Review)

Zhenhong He, Hanyu Li, Yuhan Luo, Yingying Yu, Siyu Li, Tao Zhang, Dingsu Bao
Article Number: 284
Published online on: 12 August 2026

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Expression of Concern Open Access

[Expression of Concern] Exogenous spermine attenuates diabetic kidney injury in rats by inhibiting AMPK/mTOR signaling pathway

Xinying Zhang, Li Zhang, Zhe Chen, Siwei Li, Bingbing Che, Ningning Wang, Junting Chen, Changqing Xu, Can Wei
Article Number: 283
Published online on: 12 August 2026

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Article Open Access

G protein‑coupled receptor kinase 4 governs early kidney development via STAT3 and Nhe3a

Linh Anna Trúc Vu, Julian Gerhards, Lars D. Maerz, Martin D. Burkhalter, Melanie Philipp
Article Number: 282
Published online on: 11 August 2026

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Retraction Open Access

[Retracted] Resistant starch prevents tumorigenesis of dimethylhydrazine‑induced colon tumors via regulation of an ER stress‑mediated mitochondrial apoptosis pathway  

Qiuyu Wang, Peng Wang, Zhigang Xiao
Article Number: 281
Published online on: 10 August 2026

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Review Open Access

XBP1 signaling from tumor metabolic stress to myeloid driven immunotherapy resistance (Review)

Ziwei Chen, Jiaqi Wu, Wenxi Liu, Jie Tan, Xiaochun Peng, Yanhua Zhang, Gai Liang
Article Number: 280
Published online on: 05 August 2026

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Review Open Access

Decoding miRNA‑146a: Mechanisms of action in cardiovascular diseases and endocrine metabolic disorders (Review)

Xiu Yang, Pengcheng Li, Hao Zhao
Article Number: 279
Published online on: 05 August 2026

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Review Open Access

Contribution of p38 MAPK in liver fibrosis: An overview of mechanisms, signaling pathways, and therapeutic targets (Review)

Xueqin Yang, Huarong Li, Hao Ye, Ting Wu, Fangyun Xu, Chao Hu, Chunlei Yu, Pian Ye
Article Number: 278
Published online on: 05 August 2026

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Correction Open Access

[Corrigendum] Peroxisome proliferator‑activated receptor α regulates acesulfame‑K‑induced NAFLD via hepatic PLCβ: Foe and friend

Peng-Yao Lin, Jia-Rong Xie, Tian-Chen Qian, Shi-Song Wang, Si-Yi Yu, Wen-Bo Shi, Ying Wang, Lu-Ze Cen, Qing-Jing Zhu, Yi-Yang Zheng, Hui Gao, Rong Fang, Zhao-Xia Xia, Ai-Ming Liu, Lei Xu
Article Number: 277
Published online on: 05 August 2026

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Review Open Access

Multi‑omics insights into uveitis: From mechanisms to precision medicine (Review)

Chengzhi Liu, Qiong Wu, Mingzhen Yuan, Mingyue Liu, Xinyu Wang, Jiaqi Shen, Xusheng Cao
Article Number: 276
Published online on: 03 August 2026

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Retraction Open Access

[Retracted] Effects of miRNA‑455 on cardiac hypertrophy induced by pressure overload

Chuntao Wu, Shimin Dong, Yongjun Li
Article Number: 275
Published online on: 03 August 2026

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Article Open Access

Energy stress activates AMPK to suppress ferroptosis in neurodegenerative proteinopathies

Yuanyuan Yong, Yuxin Hu, Qian Feng, Xiaogang Zhou, Lu Yu, Dalian Qin, Jianing Mi, Jianming Wu, Jianxin Liu, Anguo Wu
Article Number: 274
Published online on: 31 July 2026

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Article Open Access

Brazilin attenuates methylglyoxal‑induced endothelial injury by enhancing eIF5A hypusination and inhibiting the AMPK/mTOR‑mediated autophagy/apoptosis axis in vitro and in vivo

Yu Liang, Jinxiang Chen, Haiyang Li, Junjing Xiong, Jingcan You, Liqun Wang, Jianbo Wu, Youkun Zheng, Mao Luo
Article Number: 273
Published online on: 30 July 2026

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Review Open Access

Post‑translational modifications in atherosclerosis: Roles, mechanisms and therapeutic potential (Review)

Xiaoxiang Xu, Fei Ma, Wei Yu
Article Number: 272
Published online on: 30 July 2026

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Review Open Access

Role of extracellular matrix in liver fibrosis regression and regeneration (Review)

Yuanzhi Zhou, Zeyuan Qiang, Yang Duan, Jiwei Huang, Haichuan Wang
Article Number: 271
Published online on: 29 July 2026

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Correction Open Access

[Corrigendum] Circulating microRNA profiles and the identification of miR‑593 and miR‑511 which directly target the PROP1 gene in children with combined pituitary hormone deficiency

Yanyan Hu, Qian Wang, Zengmin Wang, Fengxue Wang, Xiaobo Guo, Guimei Li
Article Number: 270
Published online on: 29 July 2026

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Review Open Access

Unveiling the role of spatial transcriptomics in the analysis of the tumor immune microenvironment (Review)

Jialin Jiang, Xinyu Tu, Yi Cao, Qun Yan, Buqing Sai, Jian Ma
Article Number: 269
Published online on: 28 July 2026

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Expression of Concern Open Access

[Expression of Concern] Luteolin protects mice from severe acute pancreatitis by exerting HO‑1‑mediated anti‑inflammatory and antioxidant effects

Jie Xiong, Kezhou Wang, Chunxiao Yuan, Rong Xing, Jianbo Ni, Guoyong Hu, Fengling Chen, Xingpeng Wang
Article Number: 268
Published online on: 27 July 2026

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Article Open Access

circRNA_013145‑miR‑185‑5p‑RhoA axis: A novel mechanism in the pathophysiology of diabetes‑induced erectile dysfunction

Wenhan Huang, Xin Lv, Jiahua Qian, Yihao Chen, Yuhe Si, Jingwei Wang, Jianxiong Ma
Article Number: 267
Published online on: 24 July 2026

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Review Open Access

Gut‑liver‑kidney axis: A systems biology framework for understanding and treating chronic kidney disease (Review)

Jinyi Hou, Yaotan Li, Shijia Lin, Qingqing Liu, Huijuan Zheng, Weijing Liu, Yaoxian Wang, Liang Peng, Zhen Wang
Article Number: 266
Published online on: 23 July 2026

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Review Open Access

Effects of cuproptosis and its application in inflammatory bowel disease (Review)

Li Chen, Francis Atim Akanyibah, Jing Guan, Bing Pei, Bo Wang, Fei Mao
Article Number: 265
Published online on: 23 July 2026

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November-2026 Volume 58 Issue 5

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Journal Metrics

Impact Factor: 8.5

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Ferroptosis in heatstroke: Mechanisms and therapeutic perspectives (Review)

Hongguang Gao, Yang Chen, Tianshan Zhang, Yujun Shi, Rong Yao
Article Number: 313
Published online on: 10 September 2026

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Correction Open Access

[Corrigendum] Inactivation of von Hippel‑Lindau increases ovarian cancer cell aggressiveness through the HIF1α/miR‑210/VMP1 signaling pathway

Ting Liu, Le Zhao, Wei Chen, Zhen Li, Huilian Hou, Lu Ding, Xu Li
Article Number: 312
Published online on: 10 September 2026

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Review Open Access

Interferon regulatory factors orchestrate CD8+ T cell function (Review)

Fa-Xi Wang, Chun-Liang Yang, Shan-Jie Rong, Qi-Jie Chen, Xiong-Tao Yue, Fei Sun
Article Number: 311
Published online on: 08 September 2026

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Expression of Concern Open Access

[Expression of Concern] Rapamycin‑induced miR‑30a downregulation inhibits senescence of VSMCs by targeting Beclin1

Pan Tan, Haiqin Wang, Junkun Zhan, Xinyu Ma, Xingjun Cui, Yanjiao Wang, Yi Wang, Jiayu Zhong, Youshuo Liu
Article Number: 310
Published online on: 07 September 2026

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Review Open Access

Deciphering the function and mechanism of extracorporeal shock wave therapy in knee osteoarthritis (Review)

Yixuan Chen, Siqi Song, Yuchen Zhu, Shiqi Wang, Jieyuan Hu, Chenxu Liu, Yuchen Cai, Yushi Hu
Article Number: 309
Published online on: 04 September 2026

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Review Open Access

Multi‑omics integration in osteoarthritis: Unraveling cell‑type‑specific gene‑metabolite networks for precision medicine (Review)

Ying Yang, Ruichen Zheng, Yun Zhang, Dongmei Ye, Jiale Xie, Changliang Zhu
Article Number: 308
Published online on: 03 September 2026

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Review Open Access

Autophagy determines the fate of immune cells by regulating metabolic remodeling and PANoptosis (Review)

Yanan Guo, Xinyue Zhou, Yixiao Tian, Dan Chen, Xiaofeng Xie, Bin Zhou, Yingxia Tian, Yaqing Zhang
Article Number: 307
Published online on: 03 September 2026

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Review Open Access

Programmed cell death in metabolic syndrome: From molecular mechanisms to therapeutic strategies (Review)

Jialin Zhong, Maofu Zhang, Yafang Zheng, Cuicui Gong, Yasheng Deng, Lisha Sun, Dongqi Zhou, Qian Zhou, Qiu Chen
Article Number: 306
Published online on: 03 September 2026

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Review Open Access

Research progress on lysine acetylation (Review)

Minghui Zhang, Yuqi Zhang, Haoxin Yin, Junyuan Yan, Yingling Dong, Xin Zhao, Tianyi Cui, Bin Lv, Xiumei Gao
Article Number: 305
Published online on: 02 September 2026

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Expression of Concern Open Access

[Expression of Concern] Human ether‑à‑go‑go‑related gene mutation L539fs/47‑hERG leads to cell apoptosis through the endoplasmic reticulum stress pathway

Shuting Ma, Yun Zhao, Miaomiao Cao, Chaofeng Sun
Article Number: 304
Published online on: 02 September 2026

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Review Open Access

Targeting integrated cell death networks in sepsis‑associated acute kidney injury: Shared regulatory nodes and diet‑related small molecule modulation (Review)

Lin Song, Aifeng He, Wei Jiang, Keran Shi, Jing Wang, Lu Xu, Jiangquan Yu, Ruiqiang Zheng
Article Number: 303
Published online on: 31 August 2026

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Article Open Access

Effect of MALT1 inhibition by MI‑2 on the microglial phenotype switch, inflammatory cytokine secretion, neuronal loss and oxidative stress in Alzheimer's disease

Yuanlong Li, Hua Fan, Xiong Han, Ming Ni, Xiaodan Hou, Hailan Xia, Yinzhu Shi, Lin Zhang, Jun Sun
Article Number: 302
Published online on: 31 August 2026

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Review Open Access

Salvianolic acid monomers against metastasis: Decoding the multilayered interception of EMT, angiogenesis and immune evasion (Review)

Shiting Jiang, Dan Liu, Tingting Wei, Qiwei Shi, Haowen Wang, Yidan Gao, Pingsu Mao, Wenli Yang
Article Number: 301
Published online on: 31 August 2026

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Retraction Open Access

[Retracted] Silencing of decoy receptor 3 (DcR3) expression by siRNA in pancreatic carcinoma cells induces Fas ligand‑mediated apoptosis in vitro and in vivo

Jian Zhou, Shiduo Song, Songbin He, Zhenxin Wang, Bing Zhang, Dechun Li, Dongming Zhu
Article Number: 300
Published online on: 31 August 2026

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Review Open Access

Research progress on BTG2 in non‑tumor diseases (Review)

Shuling Li, Xiaomei Liu, Zheng Zhang, Ling Yang, Yuxuan Li, Qiongdan Hu
Article Number: 299
Published online on: 28 August 2026

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Review Open Access

Breaking the cycle of fibrosis: Ferroptosis as a therapeutic target (Review)

Xincheng Feng, Jue Zhang, Qinghong Ma, Chao Sun
Article Number: 298
Published online on: 27 August 2026

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Correction Open Access

[Corrigendum] Tumor‑targeting novel manganese complex induces ROS‑mediated apoptotic and autophagic cancer cell death

Jia Liu, Wenjie Guo, Jing Li, Xiang Li, Ji Geng, Qiuyun Chen, Jing Gao
Article Number: 297
Published online on: 26 August 2026

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Review Open Access

Advances in sirtuin research in lung diseases (Review)

Shuangyun Xi, Weijun Chen, Xiuli Li, Yudan Wang, Yong Ke
Article Number: 296
Published online on: 25 August 2026

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Article Open Access

lncRNA TUG1 mediates palmitic acid‑induced neuronal lipotoxic injury via the miR‑449a‑5p/caspase‑3 and Akt/GSK‑3β axes

Ya-Dong Wei, Peng-Quan Chen, Xin Zheng, Le-Qi Wu, Xin-Yi Wang, Xin-Ran Gao, Jin-Fang Ge
Article Number: 295
Published online on: 25 August 2026

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Retraction Open Access

[Retracted] Downregulation of LINC00707 promotes osteogenic differentiation of human bone marrow‑derived mesenchymal stem cells by regulating DKK1 via targeting miR‑103a‑3p

Jun Liu, Minfei Wu, Guang Feng, Rui Li, Yang Wang, Jianhang Jiao
Article Number: 294
Published online on: 24 August 2026

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