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Molecular Medicine Reports
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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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March-2015 Volume 11 Issue 3

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Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Nitric oxide synthases, S-nitrosylation and cardiovascular health: From molecular mechanisms to therapeutic opportunities (Review)

Adriana V. Treuer, Daniel R. Gonzalez
Pages: 1555-1565
Published online on: 18 November 2014

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Review

Ki67 is a promising molecular target in the diagnosis of cancer (Review)

Lian Tao Li, Guan Jiang, Qian Chen, Jun Nian Zheng
Pages: 1566-1572
Published online on: 10 November 2014

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Article

Roles of glucose transporter-1 and the phosphatidylinositol 3‑kinase/protein kinase B pathway in cancer radioresistance

Jin Fang, Shui-Hong Zhou, Jun Fan, Sen-Xiang Yan
Pages: 1573-1581
Published online on: 06 November 2014

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Review

Balance between metallothionein and metal response element binding transcription factor 1 is mediated by zinc ions (Review)

Gang Dong, Hong Chen, Meiyu Qi, Ye Dou, Qinglu Wang
Pages: 1582-1586
Published online on: 18 November 2014

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Article Open Access

Impact of losartan and angiotensin II on the expression of matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 in rat vascular smooth muscle cells

Yan-Song Guo, Zong-Gui Wu, Jun-Ke Yang, Xin-Jing Chen
Pages: 1587-1594
Published online on: 14 November 2014

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Article Open Access

Proliferative response of peripheral blood mononuclear cells in anti-Hu antibody-associated patients with paraneoplastic neurological syndrome and their depressant effect on small cell lung cancer cells

Liang Yin, Hongdang Qu, Qiming Chen
Pages: 1595-1600
Published online on: 19 November 2014

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Article Open Access

Cyclin‑dependent kinase inhibitor p21 does not impact embryonic endochondral ossification in mice

Nobuaki Chinzei, Shinya Hayashi, Shingo Hashimoto, Noriyuki Kanzaki, Kenjiro Iwasa, Shuhei Sakata, Shinsuke Kihara, Takaaki  Fujishiro, Ryosuke Kuroda, Masahiro Kurosaka
Pages: 1601-1608
Published online on: 06 November 2014

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Article Open Access

Dihydromyricetin induces mouse hepatoma Hepal‑6 cell apoptosis via the transforming growth factor‑β pathway

Bin Liu, Wei Zhou, Xiaofeng Chen, Fengming Xu, Yinqin Chen, Jie Liu, Qingyu  Zhang, Shiting Bao, Nianping Chen, Mingyi Li, Runzhi Zhu
Pages: 1609-1614
Published online on: 06 November 2014

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Article Open Access

Pre-treatment with a Xingnaojing preparation ameliorates sevoflurane-induced neuroapoptosis in the infant rat striatum

Zhou‑Jing Yang, Ying‑Wei Wang, Chang‑Lin Li, Li‑Qing Ma, Xuan Zhao
Pages: 1615-1622
Published online on: 13 November 2014

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Article Open Access

Picosecond pulsed electric fields induce apoptosis in a cervical cancer xenograft

Jia Jia, Zheng‑Ai Xiong, Qin Qin, Chen‑Guo Yao, Xiao‑Zhen Zhao
Pages: 1623-1628
Published online on: 14 November 2014

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Article Open Access

Protective effect of carboxymethylated chitosan on hydrogen peroxide-induced apoptosis in nucleus pulposus cells

Bin He, Haiying Tao, Shiqing Liu, Ailin Wei
Pages: 1629-1638
Published online on: 13 November 2014

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Article Open Access

Effects of modified Shu-Gan-Liang-Xue decoction combined with anastrozole on osteoblastic proliferation and differentiation of MC3T3-E1 cells

Fei Zhou, Shuyan Han, Ning Zhou, Wenxian Zheng, Pingping Li
Pages: 1639-1646
Published online on: 17 November 2014

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Article Open Access

Reduced tumorigenicity and drug resistance through the downregulation of octamer-binding protein 4 and Nanog transcriptional factor expression in human breast stem cells

Zheng‑Jie Huang, Jun You, Wei‑Yuan Luo, Bai‑Sheng Chen, Qing‑Zhao Feng, Bing‑Lin Wu, Long Jiang, Qi Luo
Pages: 1647-1654
Published online on: 18 November 2014

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Article Open Access

Proteasome inhibitor-induced autophagy in PC12 cells overexpressing A53T mutant α-synuclein

Danmei Lan, Wenzhao Wang, Jianhua Zhuang, Zhongxin Zhao
Pages: 1655-1660
Published online on: 27 November 2014

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Article Open Access

Effect of fibroblast growth factor 9 on the osteogenic differentiation of bone marrow stromal stem cells and dental pulp stem cells

Jingting Lu, Jiewen Dai, Xudong Wang, Maolin Zhang, Peng Zhang, Hao Sun, Xiuli Zhang, Hongbo Yu, Wenbin Zhang, Lei Zhang, Xinquan Jiang, Steve Guofang Shen
Pages: 1661-1668
Published online on: 26 November 2014

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Article Open Access

Capsinoids suppress fat accumulation via lipid metabolism

Qin Hong, Chen Xia, Hu Xiangying, Yuan Quan
Pages: 1669-1674
Published online on: 24 November 2014

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Article Open Access

Effect of Melilotus extract on lung injury via the upregulation of tumor necrosis factor-α-induced protein-8-like 2 in septic mice

Ming‑Wei Liu, Mei‑Xian Su, Yun‑Hui Wang, Chuan‑Yun Qian
Pages: 1675-1684
Published online on: 17 November 2014

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Article Open Access

Conversion of bone marrow mesenchymal stem cells into type II alveolar epithelial cells reduces pulmonary fibrosis by decreasing oxidative stress in rats

Kun Huang, Xiaowen Kang, Xinyan Wang, Shijie Wu, Jinling Xiao, Zhaoguo Li, Xiaomei Wu, Wei Zhang
Pages: 1685-1692
Published online on: 19 November 2014

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Article Open Access

Reduction of endotoxin attenuates liver fibrosis through suppression of hepatic stellate cell activation and remission of intestinal permeability in a rat non-alcoholic steatohepatitis model

Akitoshi Douhara, Kei Moriya, Hitoshi Yoshiji, Ryuichi Noguchi, Tadashi  Namisaki, Mitsuteru Kitade, Kosuke Kaji, Yosuke Aihara, Norihisa Nishimura, Kosuke  Takeda, Yasushi Okura, Hideto Kawaratani, Hiroshi Fukui
Pages: 1693-1700
Published online on: 24 November 2014

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Article Open Access

Mouse dead end 1-β interacts with c-Jun and stimulates activator protein 1 transactivation

Yong Zhang, Yan-Lin Su, Le-Sai Li, Zhi Yang, Si Chen, Jie Xiong, Xiao-Hua Fu, Xiao-Ning Peng
Pages: 1701-1707
Published online on: 14 November 2014

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Article Open Access

Effects of Treg cells and IDO on human epithelial ovarian cancer cells under hypoxic conditions

Jun Liu, Haiyan Zhang, Luoqi Jia, Hong Sun
Pages: 1708-1714
Published online on: 07 November 2014

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Article Open Access

Adiponectin reduces carotid atherosclerotic plaque formation in ApoE-/- mice: Roles of oxidative and nitrosative stress and inducible nitric oxide synthase

Xiaojun Cai, Xuan Li, Li Li, Xiao-Zhen Huang, Yu-Sheng Liu, Liang Chen, Ke  Zhang, Lin Wang, Xiaonan Li, Jiantao Song, Shuzhen Li, Yun Zhang, Mei Zhang
Pages: 1715-1721
Published online on: 13 November 2014

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Article Open Access

Adipose tissue-derived mesenchymal stem cells differentiated into hepatocyte-like cells in vivo and in vitro

Libo Yin, Yuhua Zhu, Jiangang Yang, Yijiang Ni, Zhao Zhou, Yu Chen, Lixing Wen
Pages: 1722-1732
Published online on: 13 November 2014

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Article Open Access

Hepatitis C virus represses the cellular antiviral response by upregulating the expression of signal transducer and activator of transcription 3 through sponging microRNA‑122

Yulin Xiong, Changjiang Zhang, Jing Yuan, Yan Zhu, Zhaoxia  Tan, Xuemei Kuang, Xiaohong Wang
Pages: 1733-1737
Published online on: 07 November 2014

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Article Open Access

Potential roles of the RGMa-FAK-Ras pathway in hippocampal mossy fiber sprouting in the pentylenetetrazole kindling model

Ming‑Yu Song, Fa‑Fa Tian, Yu‑Zhong Wang, Xia Huang, Jia‑Ling Guo, Dong‑Xue Ding
Pages: 1738-1744
Published online on: 21 November 2014

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Article Open Access

Effect of cyclin-dependent kinase 7 silencing on cisplatin sensitivity in endometrial carcinoma cells

Wen‑Xin Liu, Xiang‑Yu Liu, Hu Yu, Ying Chen, Quan Hao
Pages: 1745-1751
Published online on: 19 November 2014

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Article Open Access

Resveratrol exerts an anti-apoptotic effect on human bronchial epithelial cells undergoing cigarette smoke exposure

Li Zhang, Xialing Guo, Wang Xie, Yuping Li, Miao Ma, Ting Yuan, Bailing Luo
Pages: 1752-1758
Published online on: 11 November 2014

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Article Open Access

Effects of hypothermia combined with neural stem cell transplantation on recovery of neurological function in rats with spinal cord injury

Dong Wang, Jianjun Zhang
Pages: 1759-1767
Published online on: 10 November 2014

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Article Open Access

Inhibition of poly (ADP-ribose) polymerase and inducible nitric oxide synthase protects against ischemic myocardial damage by reduction of apoptosis

Juan Wang, Lin Hao, Yan Wang, Weidong Qin, Xin Wang, Tong Zhao, Yusheng  Liu, Lin  Sheng, Yimeng Du, Mengyuan Zhang, Qinghua Lu
Pages: 1768-1776
Published online on: 19 November 2014

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Article Open Access

Isolation and characterization of ex vivo expanded mesenchymal stem cells obtained from a surgical patient

Jia Huang, Huifan Sha, Guan Wang, Guoliang Bao, Shun Lu, Qingquan Luo, Qiang Tan
Pages: 1777-1783
Published online on: 06 November 2014

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Article Open Access

Paxillin regulates vascular endothelial growth factor A-induced in vitro angiogenesis of human umbilical vein endothelial cells

Wan‑Ju Yang, Yan‑Ning Yang, Jin Cao, Zi‑Hui Man, Ying Li, Yi‑Qiao Xing
Pages: 1784-1792
Published online on: 17 November 2014

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Article Open Access

Heat shock protein 72 suppresses apoptosis by increasing the stability of X-linked inhibitor of apoptosis protein in renal ischemia/reperfusion injury

Baiyu Zhang, Rong Rong, Huiyan Li, Xuan Peng, Liping Xiong, Yihan Wang, Xueqing Yu, Haiping Mao
Pages: 1793-1799
Published online on: 13 November 2014

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Article

Radiation-induced matrix metalloproteinases limit natural killer cell-mediated anticancer immunity in NCI-H23 lung cancer cells

Woong Heo, Young Shin Lee, Cheol Hun Son, Kwangmo Yang, You Soo Park, Jaeho Bae
Pages: 1800-1806
Published online on: 10 November 2014

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Article

Umbilical cord-derived mesenchymal stem cell therapy for neurological disorders via inhibition of mitogen-activated protein kinase pathway-mediated apoptosis

Ruoyu Zhang, Huaihong Chen, Zhe Zheng, Qiang Liu, Lei Xu
Pages: 1807-1812
Published online on: 19 November 2014

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Article

5-Aminolevulinic acid-induced protoporphyrin IX with multi-dose ionizing irradiation enhances host antitumor response and strongly inhibits tumor growth in experimental glioma in vivo

Junkoh Yamamoto, Shun‑Ichiro Ogura, Shohei Shimajiri, Yoshiteru Nakano, Daisuke Akiba, Takehiro Kitagawa, Kunihiro Ueta, Tohru Tanaka, Shigeru Nishizawa
Pages: 1813-1819
Published online on: 21 November 2014

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Article Open Access

Potential therapeutic mechanism of genistein in breast cancer involves inhibition of cell cycle regulation

Ling Zhang, Bo Yang, Ke Zhou, Hua Li, Dong Li, Hui Gao, Tao  Zhang, Dong Wei, Zhihui Li, Yong Diao
Pages: 1820-1826
Published online on: 10 November 2014

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Article

Mutation analysis of Leber congenital amaurosis‑associated genes in patients with retinitis pigmentosa

Tao Shen, Liping Guan, Shiqiang Li, Jianguo Zhang, Xueshan Xiao, Hui  Jiang, Jianhua Yang, Xiangming Guo, Jun Wang, Qingjiong Zhang
Pages: 1827-1832
Published online on: 07 November 2014

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Article

Expression and functional role of Nav1.9 sodium channel in cartwheel cells of the dorsal cochlear nucleus

Zhiyu Yan, Yanjun Xu, Min Liang, Xiaowei Ren
Pages: 1833-1836
Published online on: 11 November 2014

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Article

GYY4137, a hydrogen sulfide‑releasing molecule, inhibits the inflammatory response by suppressing the activation of nuclear factor‑kappa B and mitogen‑activated protein kinases in Coxsackie virus B3‑infected rat cardiomyocytes

Zubo Wu, Hua Peng, Qing Du, Wen Lin, Yali Liu
Pages: 1837-1844
Published online on: 07 November 2014

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Article

Reduction of isoproterenol-induced cardiac hypertrophy and modulation of myocardial connexin43 by a KATP channel agonist

Ji‑Min Sun, Chun‑Miao Wang, Zeng Guo, Yu‑Yu Hao, Yang‑Jing Xie, Jian Gu, Ai‑Ling Wang
Pages: 1845-1850
Published online on: 20 November 2014

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Article

Octamer-binding protein 4 affects the cell biology and phenotypic transition of lung cancer cells involving β-catenin/E-cadherin complex degradation

Zhong‑Shu Chen, Dong‑Jin Ling, Yang‑De Zhang, Jian‑Xiong Feng, Xue‑Yu  Zhang, Tian‑Sheng Shi
Pages: 1851-1858
Published online on: 21 November 2014

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Article

Omentin-1 promotes the growth of neural stem cells via activation of Akt signaling

Li‑Rong Zhao, Yu‑Jun Du, Lei Chen, Zhi‑Gang Liu, Xiao‑Yan  Jia, Yue‑Hai Pan, Jian‑Feng Liu, Bin Liu
Pages: 1859-1864
Published online on: 13 November 2014

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Article

Treatment with Lingqi capsules suppresses colorectal cancer by inhibiting the hepatocyte growth factor/c‑Met signal transduction pathway

Guo‑Sheng Wang, Jin‑Long Zhao, Huan Li
Pages: 1865-1870
Published online on: 06 November 2014

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Article

Optimizing methods for the study of intravascular lipid metabolism in zebrafish

Kan Chen, Chang-Qian Wang, Yu-Qi Fan, Yu-Shui Xie, Zhao-Fang Yin, Zuo-Jun Xu, Hui-Li Zhang, Jia-Tian Cao, Zhi-Hua Han, Yue Wang, Dong-Qiang Song
Pages: 1871-1876
Published online on: 07 November 2014

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Article

Selective colorectal cancer cell lysates enhance the immune function of mature dendritic cells in vitro

Lihong Chen, Du Meng, Lei Zhao, Rui Liu, Peisong Bai, Le Wang, Juxiang Xiao
Pages: 1877-1884
Published online on: 12 November 2014

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Article

Synthesis, characterization and in vitro and in vivo investigation of C3F8-filled poly(lactic-co-glycolic acid) nanoparticles as an ultrasound contrast agent

Cui-Wei Wang, Shi-Ping Yang, He Hu, Jing Du, Feng-Hua Li
Pages: 1885-1890
Published online on: 13 November 2014

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Article

Effects of 5‑fluorouracil and class III phosphoinositide 3‑kinase small interfering RNA combination therapy on SGC7901 human gastric cancer cells

Bao‑Song Zhu, Jia‑Lei Sun, Wei Gong, Xing‑Ding Zhang, Yong‑You Wu, Chun‑Gen Xing
Pages: 1891-1898
Published online on: 11 November 2014

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Article

Axis inhibition protein 2 polymorphisms may be a risk factor for families with isolated oligodontia

Han Qin, Jun Cai
Pages: 1899-1904
Published online on: 07 November 2014

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Article

Inhibition of osteosarcoma cell progression by MacroH2A via the downregulation of cyclin D and cyclin‑dependent kinase genes

Pu Yang, Ke Yin, Da Zhong, Qiande Liao, Kanghua Li
Pages: 1905-1910
Published online on: 07 November 2014

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Article

Curcumin-induced histone acetylation inhibition improves stress-induced gastric ulcer disease in rats

Ping He, Renmin Zhou, Guorui Hu, Zhifeng Liu, Yu Jin, Guang Yang, Mei Li, Qian Lin
Pages: 1911-1916
Published online on: 14 November 2014

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Article

Glycolysis inhibitor 2-deoxy-D-glucose suppresses carcinogen-induced rat hepatocarcinogenesis by restricting cancer cell metabolism

Zhaofa Wang, Liming Zhang, Dong Zhang, Rongsheng Sun, Qingyan Wang, Xinyi Liu
Pages: 1917-1924
Published online on: 13 November 2014

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Article

Detection of long-chain non-encoding RNA differential expression in non-small cell lung cancer by microarray analysis and preliminary verification

Yumin Wang, Gang Xu, Wei Chen, Qinshi Pan, Kate Huang, Jingye Pan, Wenhui Zhang, Jie Chen
Pages: 1925-1932
Published online on: 13 November 2014

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Article

When Cri du chat syndrome meets Edwards syndrome

Yingjun Xie, Yi Zhou, Jianzhu Wu, Yunxia Sun, Yongzhen Chen, Baojiang Chen
Pages: 1933-1938
Published online on: 10 November 2014

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Article

Protective effects of tetrandrine on brain cells in phenobarbital-dependent and -withdrawn rats

Bin Han, Ping Fu, Yun Ye, Hong Zhang, Guojun Wang
Pages: 1939-1944
Published online on: 25 November 2014

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Article

Bone marrow-derived mesenchymal stem cells protect against lung injury in a mouse model of bronchopulmonary dysplasia

Yun Luan, Wei Ding, Zhi‑Ye Ju, Zhao‑Hua Zhang, Xue Zhang, Feng Kong
Pages: 1945-1950
Published online on: 17 November 2014

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Article

Downregulation of osteopontin enhances the sensitivity of glioma U251 cells to temozolomide and cisplatin by targeting the NF-κB/Bcl‑2 pathway

Chunfa Qian, Ping Li, Wei Yan, Lei Shi, Junxia Zhang, Yingyi Wang, Hongyi Liu, Yongping You
Pages: 1951-1955
Published online on: 14 November 2014

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Article

Mild clinical manifestation and unusual recovery upon coenzyme Q10 treatment in the first Chinese Leigh syndrome pedigree with mutation m.10197 G>A

Zhiting Chen, Zhenhua Zhao, Qinyong Ye, Ying Chen, Xiaodong Pan, Bin Sun, Huapin Huang, An Zheng
Pages: 1956-1962
Published online on: 10 November 2014

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Article

An insight into the key genes and biological functions associated with insulin resistance in adipose tissue with microarray technology

Li Zhang, Ying Cui, Fangming Fu, Zhenzuo Li, Xiaoxia Pan, Hongzhuan Li, Lin Li
Pages: 1963-1967
Published online on: 10 November 2014

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Article

Roscovitine-treated HeLa cells finalize autophagy later than apoptosis by downregulating Bcl‑2

Ajda Coker‑Gurkan, Elif Damla Arisan, Pinar Obakan, Pelin Ozfiliz, Betsi Kose, Guven Bickici, Narcin Palavan‑Unsal
Pages: 1968-1974
Published online on: 07 November 2014

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Article

Resveratrol abrogates the effects of hypoxia on cell proliferation, invasion and EMT in osteosarcoma cells through downregulation of the HIF-1α protein

Yongming Sun, Haibin Wang, Ming Liu, Fanguo Lin, Jun Hua
Pages: 1975-1981
Published online on: 10 November 2014

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Article

Characteristics of stem cells derived from rat fascia: In vitro proliferative and multilineage potential assessment

Hing‑Lok Wong, Wing‑Sum Siu, Chak‑Hei Fung, Cheng Zhang, Wai‑Ting Shum, Xue‑Lin Zhou, Clara Bik‑San Lau, Jing‑Fang Zhang, Ping‑Chung Leung, Wei‑Ming Fu, Chun‑Hay Ko
Pages: 1982-1990
Published online on: 18 November 2014

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Effects of mild induced hypothermia on hippocampal connexin 43 and glutamate transporter 1 expression following traumatic brain injury in rats

Yue‑Hong Li, Chun‑Lai Zhang, Xiao‑Yan Zhang, Hong‑Xia Zhou, Ling‑Li Meng
Pages: 1991-1996
Published online on: 12 November 2014

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Association of the paired box 2 gene polymorphism with the susceptibility and pathogenesis of Henoch‑Schönlein purpura in children

Jing Chen, Xiangling Fang, Xiqiang Dang, Xiaochuan Wu, Zhuwen Yi
Pages: 1997-2003
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Overexpression of activated leukocute cell adhesion molecule in gastric cancer is associated with advanced stages and poor prognosis and miR-9 deregulation

Min Ye, Yan‑Lei Du, Yu‑Qiang Nie, Zhi‑Wei Zhou, Jie Cao, Ying‑Fei Li
Pages: 2004-2012
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Protective role of Klotho on cardiomyocytes upon hypoxia/reoxygenation via downregulation of Akt and FOXO1 phosphorylation Retraction in /10.3892/mmr.2015.3177

Fen Ai, Manhua Chen, Wei Li, Yang Yang, Guizhong Xu, Feng  Gui, Zhenxing Liu, Xiangyan Bai, Zhen Chen
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Article

Effects of long-term soft contact lens wear on the corneal thickness and corneal epithelial thickness of myopic subjects

Yulin Lei, Xiuyun Zheng, Jie Hou, Baozeng Xu, Guoying Mu
Pages: 2020-2026
Published online on: 17 November 2014

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Soluble P‑selectin promotes acute myocardial infarction onset but not severity

Ling Guo, Guizhi Sun, Guoyu Wang, Wenhu Ning, Kan Zhao
Pages: 2027-2033
Published online on: 10 November 2014

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Article

Differential expression of microRNAs and their target genes in non-small-cell lung cancer

Hui-Young Lee, Seon-Sook Han, Hwanseok Rhee, Jung Hoon Park, Jae Seung Lee, Yeon-Mok Oh, Sun Shim Choi, Seung-Ho Shin, Woo Jin Kim
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Published online on: 06 November 2014

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Effect of ulinastatin on the expression and distribution of high mobility group box 1 in human colon carcinoma cells in vitro

Yunhua Wang, Tao Tao, Yinv Dong, Jing Zhang, Zaisheng Qin
Pages: 2041-2047
Published online on: 11 November 2014

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Article

Endoplasmic reticulum stress preconditioning antagonizes low-density lipoprotein-induced inflammation in human mesangial cells through upregulation of XBP1 and suppression of the IRE1α/IKK/NF‑κB pathway

Yuan Yu, Ling Zhang, Qi Liu, Lin Tang, Hang Sun, Hui Guo
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Article

Transforming growth factor-β1 small interfering RNA inhibits growth of human embryonic lung fibroblast HFL-I cells in vitro and defends against radiation-induced lung injury in vivo

Zhonghua Lu, Yan Ma, Shuyu Zhang, Fenju Liu, Meizhen Wan, Judong Luo
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Article

Effects of sevoflurane on leucine-rich repeat kinase 2-associated Drosophila model of Parkinson's disease

Zhiming Shan, Song Cai, Tao Zhang, Liting Kuang, Qi Wang, Huanhuan Xiu, Jing Wen, Huaiyu Gu, Kangqing Xu
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Published online on: 18 November 2014

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Article

Blockade of 11β-hydroxysteroid dehydrogenase type 1 enzyme inhibits experimental collagenase-induced osteoarthritis Retraction in /10.3892/mmr.2015.4591

Faxin Li, Chuanwu Qiao, Yi Li, Jie Zhu, Jian Chen, Shuya Guo
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A preliminary study on the role of the complement regulatory protein, cluster of differentiation 55, in mice with diabetic neuropathic pain

Fachuan Nie, Dong Su, Ying Shi, Jinmei Chen, Haihui Wang, Wanxiang Qin, Yaohua Chen, Suxia Wang, Lei Li
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Antitumor activity of adenoviral vector containing T42 and 4xT42 peptide gene through inducing apoptosis of tumor cells and suppressing angiogenesis

Xiong Zhang, Dong‑Dong Qi, Ting‑Ting Zhang, Qing‑Xin Chen, Guang‑Zhi Wang, Guang‑Yu Sui, Xue‑Wei Hao, Shouli Sun, Xue Song, Ying‑Li Chen
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Article

Expression patterns of dishevelled-2 in different colon tissue segments in Hirschsprung's disease

Dong Chen, Jie Mi, Dong-Hui Fu, Wei-Lin Wang, Hong Gao
Pages: 2092-2096
Published online on: 12 November 2014

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Article

MicroRNA let-7a suppresses the growth and invasion of cholesteatoma keratinocytes

Wenjing Zhang, Xiaohua Chen, Zhaobing Qin
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Published online on: 18 November 2014

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Regulatory network of differentially expressed genes in metastatic osteosarcoma

Peng Yao, Zhi‑Bin Wang, Yuan‑Yuan Ding, Jia‑Ming Ma, Tao Hong, Shi‑Nong Pan, Jin Zhang
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Published online on: 27 November 2014

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Article

PKM2 gene regulates the behavior of pancreatic cancer cells via mitogen-activated protein kinase pathways

Jiake Feng, Tieliang Ma, Zhijun Ge, Jie Lin, Weiliang Ding, Hong Chen, Wenjiao Zhu, Sujun Zhou, Yongfei Tan
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Published online on: 20 November 2014

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Article

Reversing effect and mechanism of soluble resistance-related calcium-binding protein on multidrug resistance in human lung cancer A549/DDP cells

Yanyan Gao, Wei Li, Xiaobo Liu, Fusheng Gao, Xiaohua Zhao
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Published online on: 13 November 2014

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Berberine targets epidermal growth factor receptor signaling to suppress prostate cancer proliferation in vitro

Zheng‑Hua Huang, Hong‑Fang Zheng, Wei‑Lu Wang, Yong Wang, Long‑Fei Zhong, Jiu‑Long Wu, Qiao‑Xing Li
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Published online on: 12 November 2014

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Baicalein induces apoptosis of human cervical cancer HeLa cells in vitro

Yong Peng, Congshan Guo, Yanhong Yang, Fenglin Li, Yanxia Zhang, Bin Jiang, Qingwang Li
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Published online on: 06 November 2014

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Stress exposure and postural control in young females

Marinella Coco, Angelo Sarra Fiore, Vincenzo Perciavalle, Tizana  Maci, Maria Cristina Petralia, Valentina Perciavalle
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Novel oncolytic adenovirus sensitizes renal cell carcinoma cells to radiotherapy via mitochondrial apoptotic cell death

Ren-Fu Chen, Yue-Yan Li, Lian-Tao Li, Qian Cheng, Guan Jiang, Jun-Nian Zheng
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Annexin A2 knockdown inhibits hepatoma cell growth and sensitizes hepatoma cells to 5‑fluorouracil by regulating β‑catenin and cyclin D1 expression

Chong Wang, Yu Guo, Jing Wang, Zhiqun Min
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Article

Algal sulfated carrageenan inhibits proliferation of MDA-MB-231 cells via apoptosis regulatory genes

Hossam Murad, Ahmed Ghannam, Mahmoud Al‑Ktaifani, Assef Abbas, Mohammad Hawat
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Effects of branched-chain amino acids and zinc-enriched nutrients on prognosticators in HCV-infected patients: A multicenter randomized controlled trial

Takumi Kawaguchi, Yumiko Nagao, Kazumichi Abe, Fumio Imazeki, Koichi Honda, Kazumi Yamasaki, Koji Miyanishi, Eitaro Taniguchi, Tatsuyuki Kakuma, Junji Kato, Masataka Seike, Osamu Yokosuka, Hiromasa Ohira, Michio Sata
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Article

Domain I-IV of β2-glycoprotein I inhibits advanced glycation end product-induced angiogenesis by down-regulating vascular endothelial growth factor 2 signaling

Qian‑Qian Wang, Sai‑Jun Zhou, Zhen‑Xing Meng, Jie Wang, Rui Chen, Lin Lv, Chun‑Jun Li, De‑Min Yu, Pei Yu
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Article

Rab25 is responsible for phosphoinositide 3-kinase/AKT‑mediated cisplatin resistance in human epithelial ovarian cancer cells

Yang Fan, Long Wang, Xuechuan Han, Xueqin Liu, Hongyun Ma
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Lutein protects against ischemia/reperfusion injury in rat kidneys

Zhen‑Guo Liu, Zong‑Cai Qi, Wei‑Liang Liu, Wei‑Zhi Wang
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Article

Aberrantly expressed mRNAs and long non-coding RNAs in patients with invasive ductal breast carcinoma: A pilot study

Xuedong Chen, Jingyun Yang, Liyuan Qian, Tianzhu Cao
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Article

Identification of bile biomarkers of biliary tract cancer through a liquid chromatography/mass spectrometry-based metabolomic method

Xiaofeng Xu, Shaobing Cheng, Chaofeng Ding, Zhen  Lv, Deying Chen, Jian Wu, Shusen Zheng
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Calcium ions promote primary renal epithelial cell differentiation into cells with bone-associated phenotypes via transforming growth factor-β1-induced epithelial-mesenchymal transition in idiopathic hypercalciuria patients

Deng He, Shaogang Wang, Zhaohui Jia, Lei Cui, Yuchao Lu, Henglong Hu, Baolong Qin
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Inhibition of the signal transducer and activator of transcription 3 signaling pathway by Qianliening capsules suppresses the growth and induces the apoptosis of human prostate cells

Jiumao Lin, Jianheng Zhou, Xiaoyong Zhong, Zhenfeng Hong, Jun Peng
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Published online on: 13 November 2014

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mRNA expression of glucocorticoid receptor and serological and virological markers of chronic hepatitis B

Bing Mei, Yongling Chen, Weijia Liu, Linyun Li, Changfu Wang
Pages: 2215-2220
Published online on: 12 November 2014

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Article

Apigenin inhibits the self-renewal capacity of human ovarian cancer SKOV3‑derived sphere-forming cells

Ai‑Qiong Tang, Xiao‑Cheng Cao, Li Tian, Lihua He, Fei Liu
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Published online on: 18 November 2014

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Article

Cardioprotective effects of tilianin in rat myocardial ischemia-reperfusion injury

Xinhong Guo, Wenjiang Cao, Jiaming Yao, Yong Yuan, Ye  Hong, Xinchun Wang, Jianguo Xing
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Published online on: 14 November 2014

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Antitumor and apoptotic activities of the chemical constituents from the ethyl acetate extract of Artemisia indica

Ying‑Tong Zeng, Jian‑Min Jiang, Hai‑Yan Lao, Jie‑Wen Guo, Yu‑Ning Lun, Min Yang
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Downregulation of gangliotetraosylceramide and β1,3-galactosyltransferase‑4 gene expression by Smads during transforming growth factor β‑induced epithelial‑mesenchymal transition

Jia Guo, Bo Song, Xiang Li, Chenhui Hε, Ganglong Yang, Xiaomin Yang, Feng Guan
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MicroRNA-451a is associated with cell proliferation, migration and apoptosis in renal cell carcinoma

Zhengming Su, Liangchao Ni, Wenshui Yu, Zuhu Yu, Duqun  Chen, Enpu Zhang, Yifan Li, Yadong Wang, Xianxin Li, Shangqi  Yang, Yaoting Gui, Yongqing Lai, Jiongxian Ye
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Published online on: 14 November 2014

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Article

Twist‑related protein 1 enhances oral tongue squamous cell carcinoma cell invasion through β‑catenin signaling

Lian Zheng, Ning Li, Feng Guo, Xin‑Chun Jian, Can‑Hua  Jiang, Ping Yin, An‑Jie Min, Long Huang
Pages: 2255-2261
Published online on: 07 November 2014

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Article

para-Phenylenediamine-induces apoptosis via a pathway dependent on PTK-Ras-Raf-JNK activation but independent of the PI3K/Akt pathway in NRK-52E cells

Reena A.P. Kasi, Chye Soi Moi, Yip Wai Kien, Koh Rhun Yian, Ng Wei Chin, Ng Khuen Yen, Gnanajothy Ponnudurai, Seow Heng Fong
Pages: 2262-2268
Published online on: 19 November 2014

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Article

Downregulation of c-Met expression does not enhance the sensitivity of gastric cancer cell line MKN-45 to gefitinib

Jin‑An Ma, Chunhong Hu, Wenjuan Li, Jing Ren, Fangwen  Zou, Dongai Zhou, Wen Zou, Yajun Wei, Ying Zhou
Pages: 2269-2275
Published online on: 13 November 2014

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Article

Localization and expression of heat shock protein 70 with rat myocardial cell damage induced by heat stress in vitro and in vivo

Hongbo Chen, Abdelnasir Adam, Yanfen Cheng, Shu Tang, Jörg Hartung, Endong Bao
Pages: 2276-2284
Published online on: 20 November 2014

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Article

Differential microRNA expression profile comparison between epidermal stem cells and differentiated keratinocytes

Zhifang Song, Dewu Liu, Yan Peng, Jin Li, Zhiwei Zhang, Pu Ning
Pages: 2285-2291
Published online on: 06 November 2014

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Article

Cyclic stretch induces human bladder smooth muscle cell proliferation in vitro through muscarinic receptors

Yi Dai, Ye Tian, De-Yi Luo, Romel Wazir, Xuan Yue, Hong Li, Kun-Jie Wang
Pages: 2292-2298
Published online on: 19 November 2014

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Article

Expression of B-cell-associated genes in peripheral blood mononuclear cells of patients with symptomatic pulmonary embolism

Wei Lv, Qianglin Duan, Lemin Wang, Zhu Gong, Fan Yang, Yanli Song
Pages: 2299-2305
Published online on: 19 November 2014

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Article

Suppression of dendritic cell and T-cell activation by the pRST98 Salmonella plasmid

Li Wei, Qili Jin, Yuanyuan Chu, Shuyan Wu, Rui Huang
Pages: 2306-2314
Published online on: 10 November 2014

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Article

Upregulation of Stat1-HDAC4 confers resistance to etoposide through enhanced multidrug resistance 1 expression in human A549 lung cancer cells Retraction in /10.3892/mmr.2025.13461

Chutima Kaewpiboon, Ratakorn Srisuttee, Waraporn Malilas, Jeong Moon, Sangtaek Oh, Hye Gwang Jeong, Randal N. Johnston, Wanchai Assavalapsakul, Young‑Hwa Chung
Pages: 2315-2321
Published online on: 14 November 2014

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Article

Increased monocytic CD14+HLADRlow/- myeloid-derived suppressor cells in obesity

Yi Bao, Juanfen Mo, Lingjuan Ruan, Guo Li
Pages: 2322-2328
Published online on: 11 November 2014

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Article

Docosahexanoic acid modifies low-density lipoprotein receptor abundance in HepG2 cells via suppression of the LXRα‑Idol pathway

Ying Zhou, Yue Guo, Xiaodong Zhuang, Zhimin Du
Pages: 2329-2333
Published online on: 13 November 2014

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Article

Simvastatin induces growth inhibition and apoptosis in HepG2 and Huh7 hepatocellular carcinoma cells via upregulation of Notch1 expression

Xin Huang, Jiancang Ma, Jinkai Xu, Qinghua Su, Jun Zhao
Pages: 2334-2340
Published online on: 19 November 2014

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Article

Endoplasmic reticulum stress protects human thyroid carcinoma cell lines against ionizing radiation-induced apoptosis

Xin‑Yu Wu, Rui‑Tai Fan, Xin‑Hui Yan, Jing Cui, Jun‑Ling Xu, Hao Gu, Yong‑Ju Gao
Pages: 2341-2347
Published online on: 14 November 2014

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Propofol alleviates acute lung injury following orthotopic autologous liver transplantation in rats via inhibition of the NADPH oxidase pathway

Gangjian Luo, Guosong Zhu, Dongdong Yuan, Weifeng Yao, Xinjin Chi, Ziqing Hei
Pages: 2348-2354
Published online on: 11 November 2014

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MicroRNA-155 promotes the proliferation and invasion abilities of colon cancer cells by targeting quaking

Bin He, Sheng‑Qiang Gao, Li‑Dong Huang, Yue‑Han Huang, Qi‑Yu Zhang, Meng‑Tao Zhou, Hong‑Qi Shi, Qi‑Tong Song, Yun‑Feng Shan
Pages: 2355-2359
Published online on: 21 November 2014

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TGM1 as a novel signature gene in psoriasis identified by integrative bioinformatics and experimental validation

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CDK1‑induced regulation of p53 phosphorylation at Ser315 mediates cell cycle arrest and apoptosis of macrophages infected with clinical isolates of Mycobacterium tuberculosis

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Identification of multimorbidity hub genes for knee osteoarthritis-atherosclerosis and potential clinical applications

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[Retracted] Baicalin inhibits influenza virus A replication via activation of type I IFN signaling by reducing miR‑146a

Rui Li, Lianxin Wang
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Protective effects of Notoginsenoside R1 on the ferroptosis of a human non‑small cell lung cancer cell line

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Dihydroalterperylenol from endophytic fungus Alternaria semiverrucosa and its antitumour activity uncovered by transcriptome analysis, molecular docking and molecular dynamics simulations

Mingfei Yang, Yongzhong Lu, Long Han, Zhangjiang He, Jichuan Kang
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[Retracted] Phosphoinositide 3‑kinase/Akt pathway is involved in pingyangmycin‑induced growth inhibition, apoptosis and reduction of invasive potential in EOMA mouse hemangioendothelioma cells

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Schisantherin A induces ferroptosis in non‑small cell lung cancer through activation of the YAP/ACSL4/TfR signaling pathway

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[Corrigendum] Early anticoagulation therapy for severe burns complicated by inhalation injury in a rabbit model

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Retraction Open Access

[Retracted] Oxymatrine‑mediated maturation of dendritic cells leads to activation of FOXP3+/CD4+ Treg cells and reversal of cisplatin‑resistance in lung cancer cells

Hui Liu, Manman Zou, Pei Li, Haifeng Wang, Xijun Lin, Jin Ye
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Zinc finger protein 514 promotes esophageal cancer progression by enhancing cell proliferation, migration and invasion

Lin Lv, Xiaoming Sun, Houlu Zhang, Guangxu Wang, Chao Zhang, Haibo Liu, Liangming Zhu
Article Number: 14
Published online on: 24 October 2025

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Effects of zinc carnosine on bone loss in mice with diabetic osteoporosis 

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Published online on: 24 October 2025

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Rapamycin improves endometriosis‑related infertility involving ovarian senescence via the PPARα/IGFBP2 pathway

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Article Number: 12
Published online on: 24 October 2025

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Combining tadalafil and hyperbaric oxygen therapy protects against ovarian ischemia‑reperfusion damage in rats

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Published online on: 23 October 2025

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Liquid‑liquid phase separation of PHLDB2 promotes oral squamous cell carcinoma metastasis through regulating epithelial mesenchymal transition and PIK3CA expression

Kunyi Chen, Yuhong Wang, Jianing Cui, Qianrui Liu, Xiaoyong Liu, Wenjin Wang, Jinsong Hou
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Published online on: 22 October 2025

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Mitochondrial gatekeeper in hepatocellular carcinoma: Unraveling the multifaceted roles of VDAC in metabolic reprogramming, apoptosis evasion and therapeutic innovation (Review)

Jie Wang, Yu Liang, Xiaotao Jia, Xinmao Yang, Danning Shi, Yuanchun Wang, Yanfang Pan
Article Number: 9
Published online on: 21 October 2025

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[Retracted] Knockdown of ubiquitin‑specific protease 51 attenuates cisplatin resistance in lung cancer through ubiquitination of zinc‑finger E‑box binding homeobox 1

Feng Zhou, Chunling Du, Donghui Xu, Jinchang Lu, Lei Zhou, Chaomin Wu, Bo Wu, Jianan Huang
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Published online on: 20 October 2025

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Exploring the role of cytochrome P450 family 1 subfamily B member 1 and quercetin in modulating neuropathic pain after spinal cord injury

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Article Number: 7
Published online on: 15 October 2025

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R‑loops in hepatocellular carcinoma: Bridging genomic instability and therapeutic opportunity (Review)

Ching-Hua Hsieh, Yueh-Wei Liu, Pei-Chin Chuang
Article Number: 6
Published online on: 15 October 2025

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Role and relevance of exosome-mediated epigenetic regulation in the pathogenesis, diagnosis and treatment of 
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Yishuo Zhang, Shanshan Zhang, Yijing Li, Wenqi Jin, Liya Zhou, Jing Lu
Article Number: 5
Published online on: 15 October 2025

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PLIN5 deficiency ameliorates metabolic dysfunction‑associated fatty liver disease by inhibiting ferroptosis

Ya Li, Xiaohan Wang, Xuecui Yin, Xiaohui Zhu, Weiqi Cui, Lin Dong, Yu Xia, Ying Wang, Liu Liu, Pengyuan Zheng, Youcai Tang
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Published online on: 14 October 2025

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Circadian clock genes: Their influence on liver metabolism, disease development and treatment (Review)

Junmin Wang, Mengxing Cao, Shen Li, Wen Pei, Jing Li, Zhen Wang
Article Number: 3
Published online on: 14 October 2025

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MALT1 inhibition by MI‑2 suppresses epithelial‑to‑mesenchymal transition and fibrosis by inactivating the NF‑κB pathway in high glucose‑treated HK‑2 cells

Yating Lan, Jian Ma, Huijun Chen, Chaohong Lan, Na Zhao
Article Number: 2
Published online on: 14 October 2025

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[Retracted] Protective effect of erythropoietin against myocardial injury in rats with sepsis and its underlying mechanisms

Xinliang Zhang, Shimin Dong, Yanjun Qin, Xiaohua Bian
Article Number: 1
Published online on: 14 October 2025

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February-2026 Volume 33 Issue 2

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Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

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Mitophagy and oxidative stress in chronic kidney disease (Review)

Quwu Mushuo, Yihuai Tian, Jianchun Li, Yanqin Qiu, Hui Fan, Qiongdan Hu, Qiong Zhang
Article Number: 61
Published online on: 04 December 2025

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ABCC9 knockdown attenuates isoproterenol‑induced myocardial hypertrophy by inhibiting the PI3K/AKT signaling pathway

Qian Peng, Rui Chang, Linlin Ma, Yanfei Li
Article Number: 60
Published online on: 04 December 2025

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MeCP2 suppresses ferroptosis to drive EMT in retinal pigment epithelial cells: Implications for PVR pathogenesis

Sibei Guo, Yongya Zhang, Xue Li, Xueru Zhao, Yingjuan Liang, Xiaohua Li
Article Number: 59
Published online on: 04 December 2025

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[Corrigendum] Screening for implicated genes in colorectal cancer using whole‑genome gene expression profiling

Long-Ci Sun, Hai-Xin Qian
Article Number: 58
Published online on: 04 December 2025

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Hyperoside prevents osteoporosis by activating the PI3K/AKT signaling pathway to inhibit oxidative stress and promote osteogenesis

Lirong Li, Huaidong Deng, Shabin Zhuan, Boyu Wu, Dawei Xiao
Article Number: 57
Published online on: 03 December 2025

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[Retracted] Interference with Tim‑3 protein expression attenuates the invasion of clear cell renal cell carcinoma and aggravates anoikis

Muming Yu, Bin Lu, Yancun Liu, Ying Me, Lijun Wang, Hui Li
Article Number: 56
Published online on: 01 December 2025

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Acetylshikonin induces ferroptosis via the lipid peroxidation pathway in osteosarcoma cells

Ji-Ying Chen, Guo-Shou Wang, Tsung-Ming Chang, Ju-Fang Liu
Article Number: 55
Published online on: 27 November 2025

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Liver X receptor: A potential target for inflammatory bowel disease and colorectal cancer (Review)

Yingjie Li, Xiaoyan Fu, Meiwen Bai, Jiaqi Zhou, Jiatai Qiu, Hongxia Zhang, Shujuan Liang, Meifang Liu
Article Number: 54
Published online on: 27 November 2025

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lncRNA NEAT1 promotes the proliferation of hemangioma cells by transcriptionally activating β‑catenin via enhancing H3K18 lactylation

Li Yu, Nian Zhou, Xiao-Liang Zhang, Xue-Jing Pang, Lu Xing, Yun-Jing Pu, Li Zhang, Jing-Nan Wu, Hong Shu
Article Number: 53
Published online on: 25 November 2025

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[Retracted] MicroRNA‑206 exerts anti‑oncogenic functions in esophageal squamous cell carcinoma by suppressing the c‑Met/AKT/mTOR pathway

Jin Zhang, Xianen Fa, Qingyong Zhang
Article Number: 52
Published online on: 25 November 2025

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