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Molecular Medicine Reports
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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
January 2013 Volume 7 Issue 1

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article

Inhalation of carbon monoxide following resuscitation ameliorates hemorrhagic shock-induced lung injury

Susumu Kawanishi, Toru Takahashi, Hiroshi Morimatsu, Hiroko Shimizu, Emiko Omori, Kenji Sato, Masaki Matsumi, Shigeru Maeda, Atsunori Nakao, Kiyoshi Morita
Pages: 3-10
Published online on: 08 November 2012

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Article Open Access

Clinical utility of the Xpert MRSA assay for early detection of methicillin-resistant Staphylococcus aureus

Ae-Chin Oh, Jin Kyung Lee, Ha Na Lee, Young Jun Hong, Yoon Hwan Chang, Seok-Il Hong, Dong Ho Kim
Pages: 11-15
Published online on: 09 October 2012

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Article Open Access

Advanced glycation end-products stimulate basic fibroblast growth factor expression in cultured Müller cells

Jing Ai, Yao Liu, Jun-Hui Sun
Pages: 16-20
Published online on: 24 October 2012

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Article Open Access

Epidemiology and resistance mechanisms to imipenem in Klebsiella pneumoniae: A multicenter study

Huihong Chen, Xue Yuehua, Weiwei Shen, Hua Zhou, Lizhong Zhou, Zhaoyun Li
Pages: 21-25
Published online on: 25 October 2012

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Article

Antitumor activity of Pulsatilla koreana extract in anaplastic thyroid cancer via apoptosis and anti-angiogenesis

Byung Hee Park, Kyung Hee Jung, Mi Kwon Son, Ju Hyeon Seo, Hee-Seung Lee, Ju-Hee Lee, Soon-Sun Hong
Pages: 26-30
Published online on: 05 November 2012

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Article

Treadmill and wheel exercise alleviate lipopolysaccharide-induced short-term memory impairment by enhancing neuronal maturation in rats

Sung-Eun Kim, Il-Gyu Ko, Chang-Youl Park, Mal-Soon Shin, Chang-Ju Kim, Yong-Seok Jee
Pages: 31-36
Published online on: 29 October 2012

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Article

Synergistic effect of scavenger receptor A and low-density lipoprotein receptor on macrophage foam cell formation under inflammatory stress

Tianyi Su, Lei Zhao, Xiongzhong Ruan, Guoqing Zuo, Jianping Gong
Pages: 37-42
Published online on: 08 November 2012

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Article

Expression and the clinical significance of hPTTG1 in gastric cancer

Zuyan Luo, Bo Li, Junfa Chen, Yingyu Ma, Houquan Tao
Pages: 43-46
Published online on: 01 November 2012

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Article

Effects of apocynin on oxidative stress and expression of apoptosis-related genes in testes of diabetic rats

Mingchao Li, Zhuo Liu, Li Zhuan, Tao Wang, Shuiming Guo, Shaogang Wang, Jihong Liu, Zhangqun Ye
Pages: 47-52
Published online on: 17 October 2012

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Article

Increased expression levels of vitronectin in the maternal‑fetal interface of placenta in early-onset severe preeclampsia

Jing Shen, Xiaoyan Ma, Fei Yi, Azhar Rasul, Manhua Cui, Tonghui Ma
Pages: 53-58
Published online on: 22 October 2012

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Article

Anticancer activities of tanshinone microemulsion against hepatocellular carcinoma in vitro and in vivo

Hui Ma, Qing Fan, Jia Yu, Jile Xin, Ce Zhang
Pages: 59-64
Published online on: 12 October 2012

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Article

Identification of differentially expressed microRNAs and the possible role of miRNA-126* in Sprague-Dawley rats during fetal lung development

Yang Yang, Xiao-Dan Pu, Kan Qing, Xi-Rong Guo, Xiao-Yu Zhou, Xiao-Guang Zhou
Pages: 65-72
Published online on: 15 October 2012

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Article

Detection of IL-6 by magnetic nanoparticles grown with the assistance of mid-infrared lighting

Xiufeng Jiang, Ye Zhang, Xiaofei Miao, Zenghui Li, Zengtao Bao, Tong Wang
Pages: 73-76
Published online on: 19 October 2012

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Article

Application of a NotI subtraction and methylation‑specific genome subtractive hybridization technique in the detection of genomic DNA methylation differences between hydatidiform moles and villi

Gang Zou, Xiling Du, Tony Duan, Te Liu
Pages: 77-82
Published online on: 07 November 2012

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Article

Gastric motility in ghrelin receptor knockout mice

Cheng-Guang Yang, Wei-Gang Wang, Jun Yan, Jian Fei, Zhi-Gang Wang, Qi Zheng
Pages: 83-88
Published online on: 29 October 2012

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Article

Comparison of three methods for the detection of Epstein-Barr virus in Hodgkin's lymphoma in paraffin-embedded tissues

Zong-Li Qi, Xi-Qun Han, Jun Hu, Guang-Hua Wang, Jin-Wei Gao, Xin Wang, Dao-Yan Liang
Pages: 89-92
Published online on: 01 November 2012

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Article

Role of the JAK/STAT signaling pathway in the pathogenesis of acute myocardial infarction in rats and its effect on NF-κB expression

Song Zhang, Xin Liu, Steven Goldstein, Yigang Li, Junbo Ge, Ben He, Xuetao Fei, Zuyue Wang, George Ruiz
Pages: 93-98
Published online on: 29 October 2012

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Article

Repair of mandibular defects by bone marrow stromal cells expressing the basic fibroblast growth factor transgene combined with multi-pore mineralized Bio-Oss

Chunyan Yang, Yang Liu, Chunming Li, Bin Zhang
Pages: 99-104
Published online on: 08 November 2012

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Article

Investigation of the correlation between norepinephrine transporter gene polymorphisms and essential hypertension

Ying Li, Liqiang Zheng, Dingyin Zeng, Ying Hao, Baogang Wu, Yingxian Sun
Pages: 105-109
Published online on: 18 October 2012

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Article

Effects of fluid shear stress on the expression of Omi/HtrA2 in human umbilical vein endothelial cells

Liang-Liang Sun, Le Zhang, Xiang-Lan Meng, Feng Zhang, Yun Zhao, Xin Jin
Pages: 110-114
Published online on: 22 October 2012

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Article

P-gp upregulation may be blocked by natural curcuminoids, a novel class of chemoresistance-preventing agent

Dong Xu, Wei Tian, Hong Shen
Pages: 115-121
Published online on: 27 September 2012

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Article

TP53 gene deletion in esophageal cancer tissues of patients and its clinical significance

Madiniyet Niyaz, Abdugheni Turghun, Zhang Hai Ping, Zhang Zhu, Ilyar Sheyhedin, Cai Ren, Idiris Awut
Pages: 122-126
Published online on: 01 November 2012

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Article

Risk of cardiovascular disease is suppressed by dietary supplementation with protamine and chitooligosaccharide in Sprague-Dawley rats

Nam-Hee Kang, Won Kyung Lee, Bo-Rim Yi, Hye-Rim Lee, Min-Ah Park, Sang-Ki Park, Hyoung Kook Park, Kyung-Chul Choi
Pages: 127-133
Published online on: 12 October 2012

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Article

B7-H3 expression in ductal and lobular breast cancer and its association with IL-10

Chuanyong Liu, Jie Liu, Jie Wang, Yan Liu, Fang Zhang, Wenli Lin, Aiqin Gao, Meili Sun, Yunshan Wang, Yuping Sun
Pages: 134-138
Published online on: 29 October 2012

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Article

Correlation between SATB1 and Bcl-2 expression in human glioblastoma multiforme

Sheng-Hua Chu, Yan-Bin Ma, Dong-Fu Feng, Zhi-Qiang Li, Pu-Cha Jiang
Pages: 139-143
Published online on: 16 October 2012

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Article

The effect of vacuum freeze-drying and radiation on allogeneic aorta grafts

Qing Cao, Leren Tao, Mengfang Liu, Meng Yin, Kun Sun
Pages: 144-148
Published online on: 24 October 2012

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Article

Effect of antisense TIMP-1 cDNA on the expression of TIMP-1 and MMP-2 in lung tissue with pulmonary fibrosis induced by bleomycin

Haiying Tang, Jingwei Mao, Lili Gao, Jia Liu, Taihua Wu
Pages: 149-153
Published online on: 22 October 2012

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Article

Hirsutine, an indole alkaloid of Uncaria rhynchophylla, inhibits inflammation-mediated neurotoxicity and microglial activation

Hwan Yong Jung, Kyong Nyon Nam, Byung-Choel Woo, Kyoo-Pil Kim, Sung-Ok Kim, Eunjoo H. Lee
Pages: 154-158
Published online on: 19 October 2012

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Article

Macrophages overexpressing Aire induce CD4+Foxp3+ T cells

Jitong Sun, Haiying Fu, Jing Wu, Wufei Zhu, Yi Li, Wei Yang
Pages: 159-165
Published online on: 24 October 2012

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Article

Regulatory effects of apoptosis-associated speck-like protein on cytokines in the P388D1 macrophage-like cell line

Shuangyi Ren, Hailong Chen
Pages: 166-170
Published online on: 12 October 2012

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Article

Administration of heat shock protein 65 inhibits murine melanoma growth in vivo

Jie Yang, Yanfei Xie, Huaqian Wang, Yi Yao, Jing Hou, Yanjun Ma, Qing Zhang, Yun Xing, Jie Wu, Taiming Li, Junnian Zheng, Jingjing Liu, Rongyue Cao
Pages: 171-176
Published online on: 06 November 2012

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Article

Effects of probucol on angiotensin II-induced BMP-2 expression in human umbilical vein endothelial cells

Ming Zhang, Jian Wang, Jing-Hua Liu, Shu-Juan Chen, Bin Zhen, Chang-Hua Wang, Hua He, Chen-Xi Jiang
Pages: 177-182
Published online on: 24 October 2012

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Article

Effects of exercise therapy on knee joint function and synovial fluid cytokine levels in patients with knee osteoarthritis

Shao-Lan Zhang, Hong-Qi Liu, Xiao-Zu Xu, Juan Zhi, Jiao-Jiao Geng, Jin Chen
Pages: 183-186
Published online on: 07 November 2012

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Article

Effect of fractionated irradiation on the expression of multidrug resistance genes in the CNE1 human nasopharyngeal carcinoma cell line

Xue-Ning Ji, Fang Yang, Xiao-Mei Sui, Fu-Guang Wang, Ri-Guang Ge, Xiu-Lian Quan, Tong Zhao, Bin Wen Gao, Ruo-Yu Wang
Pages: 187-194
Published online on: 24 October 2012

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Article

A Chinese herbal decoction can increase the intracellular Ca2+ concentration and CatSper1 expression in mouse sperm tails

Shaobo Luo, Jinming Jia, Haixiang Hu, Weiguo Ma, Yongzheng Jiao, Jiachen Dong
Pages: 195-200
Published online on: 08 October 2012

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Article

Establishment of an optimized PCR method using sequence-specific primers for screening multiple gene polymorphisms simultaneously

Rui Yang, Jun-He Zhang, Guo-Yan Yuan
Pages: 201-204
Published online on: 09 October 2012

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Article

Galectin-9 promotes TGF-β1-dependent induction of regulatory T cells via the TGF-β/Smad signaling pathway

Kun Lv, Yingying Zhang, Mengying Zhang, Min Zhong, Qifeng Suo
Pages: 205-210
Published online on: 12 October 2012

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Article

Hydrodynamic-based delivery of PTP1B shRNA reduces plasma glucose levels in diabetic mice

Sanaz Vakili, Shadi Sadat Seyyed Ebrahimi, Asie Sadeghi, Sattar Gorgani-Firuzjaee, Maani Beigy, Parvin Pasalar, Reza Meshkani
Pages: 211-216
Published online on: 08 November 2012

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Article

Abnormal expression of seven myogenesis-related genes in extraocular muscles of patients with concomitant strabismus

Yujuan Zhu, Daming Deng, Chongde Long, Guorong Jin, Qingjiong Zhang, Huangxuan Shen
Pages: 217-222
Published online on: 24 October 2012

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Article

Expression of ghrelin and leptin during the development of type 2 diabetes mellitus in a rat model

Songyun Zhang, Qingjiu Zhang, Lihui Zhang, Cege Li, Huiqing Jiang
Pages: 223-228
Published online on: 25 October 2012

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Article

MicroRNA-125b expression in gastric adenocarcinoma and its effect on the proliferation of gastric cancer cells

Zhao-Xu Yang, Cheng-Yi Lu, Yan-Ling Yang, Ke-Feng Dou, Kai-Shan Tao
Pages: 229-232
Published online on: 26 October 2012

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Article

Insulinotropic action of Citrullus colocynthis seed extracts in rat pancreatic islets

Nabila Benariba, Rabeh Djaziri, Emeline Hupkens, Karim Louchami, Willy J. Malaisse, Abdullah Sener
Pages: 233-236
Published online on: 24 October 2012

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Article

CD8+ T cells from vitiligo perilesional margins induce autologous melanocyte apoptosis

Jilong Wu, Miaoni Zhou, Yinsheng Wan, Aie Xu
Pages: 237-241
Published online on: 08 October 2012

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Article

Heme oxygenase-1-mediated reactive oxygen species reduction is involved in the inhibitory effect of curcumin on lipopolysaccharide-induced monocyte chemoattractant protein-1 production in RAW264.7 macrophages

Yi Zhong, Tingrong Liu, Wenyan Lai, Ying Tan, Di Tian, Zhigang Guo
Pages: 242-246
Published online on: 22 October 2012

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Article

Protective effects of hydrogen sulfide on oxidative stress and fibrosis in hepatic stellate cells

Hai-Ning Fan, Hai-Jiu Wang, Cai-Rang Yang-Dan, Li Ren, Cong Wang, Yan-Fei Li, Yong Deng
Pages: 247-253
Published online on: 25 October 2012

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Article

Expression of MAGE-A11 in breast cancer tissues and its effects on the proliferation of breast cancer cells

Li-Ping Xia, Min Xu, Yan Chen, Wei-Wei Shao
Pages: 254-258
Published online on: 12 October 2012

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Article

β-adrenergic receptor polymorphisms in susceptibility, response to treatment and prognosis in heart failure: Implication of ethnicity

Sabrina Bernardez Pereira, Mônica Wanderley Monçores Velloso, Sérgio Chermont, Mônica Maria Pena Quintão, Rosemery Nunes Abdhala, Camila Giro, Thiago Oliveira E Alves, Viviane Camacho, Luiza De Fátima Maia Contarato, Felipe Montes Pena, Henrique Miller Balieiro, Maria Luiza Rosa Garcia, Antônio Cláudio Lucas Da Nóbrega, Georgina Severo Ribeiro, Evandro Tinoco Mesquita
Pages: 259-265
Published online on: 09 October 2012

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Article

Baicalein induces apoptosis via a mitochondrial-dependent caspase activation pathway in T24 bladder cancer cells

Hong-Liang Li, Shu Zhang, Yuan Wang, Rong-Rui Liang, Jun Li, Peng An, Zi-Ming Wang, Jun Yang, Zong-Fang Li
Pages: 266-270
Published online on: 09 October 2012

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Article

Enhanced N-terminal degradation of troponin I blunts cardiac function responsiveness to isoproterenol in 4-week tail-suspended rats

Lin Zhang, Zhen Song, Hui Chang, Yun-Ying Wang, Zhi-Bin Yu
Pages: 271-279
Published online on: 08 October 2012

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Article

Role of CYP1A2 polymorphisms in breast cancer risk in women

Imene Ayari, Ugo Fedeli, Saad Saguem, Samir Hidar, Saida Khlifi, Sofia Pavanello
Pages: 280-286
Published online on: 01 November 2012

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Article

Association of pre-miRNA-146a rs2910164 and pre‑miRNA-499 rs3746444 polymorphisms and susceptibility to rheumatoid arthritis

Mohammad Hashemi, Ebrahim Eskandari-Nasab, Zahra Zakeri, Mahdi Atabaki, Gholamreza Bahari, Mahdi Jahantigh, Mohsen Taheri, Saeid Ghavami
Pages: 287-291
Published online on: 08 November 2012

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Article

Effect of microtopographic structures of silk fibroin on endothelial cell behavior

Jin-Yun Tan, Jian-Chuan Wen, Wei-Hao Shi, Qing He, Lei Zhu, Kun Liang, Zheng-Zhong Shao, Bo Yu
Pages: 292-298
Published online on: 12 October 2012

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Article

Effects of IL-1β on the proliferation and apoptosis of gastric epithelial cells and acid secretion from isolated rabbit parietal cells

Tao Guo, Jia-Ming Qian, Yu-Qing Zhao, Xiao-Bo Li, Jian-Zhong Zhang
Pages: 299-305
Published online on: 02 November 2012

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Article

Maternal protein restriction in rats leads to reduced PGC-1α expression via altered DNA methylation in skeletal muscle

Yu Zeng, Pingqing Gu, Kangsheng Liu, Peilin Huang
Pages: 306-312
Published online on: 19 October 2012

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Article

Association of myeloperoxidase gene variation with carotid atherosclerosis in patients with essential hypertension

Jinrui Fang, Liya Ma, Shuhong Zhang, Yan Fang, Peng Su, Huiyuan Ma
Pages: 313-317
Published online on: 23 October 2012

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Article

Proteomic analysis of TNF-α-activated endothelial cells and endothelial microparticles

Yiyun Liu, Wenchang Huang, Ruyuan Zhang, Jun Wu, Lei Li, Yaoqing Tang
Pages: 318-326
Published online on: 22 October 2012

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Article

Attenuation of brain edema and spatial learning deficits by the inhibition of NADPH oxidase activity using apocynin following diffuse traumatic brain injury in rats

Si-Xin Song, Jun-Ling Gao, Kai-Jie Wang, Ran Li, Yan-Xia Tian, Jian-Qiang Wei, Jian-Zhong Cui
Pages: 327-331
Published online on: 24 October 2012

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Article

mRNA expression of interleukins and Th1/Th2 imbalance in patients with pulmonary embolism

Qianglin Duan, Wei Lv, Lemin Wang, Zhu Gong, Qiang Wang, Haoming Song, Hao Wang
Pages: 332-336
Published online on: 23 October 2012

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Article

Validation of tumor markers in central nervous system germ cell tumors by real-time reverse transcriptase polymerase chain reaction using formalin-fixed paraffin-embedded tissues

Dowhan Kim, Da Hye Lee, Junjeong Choi, Kyu Won Shim, Se Hoon Kim
Pages: 337-341
Published online on: 23 October 2012

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Article

Association of promoter methylation and 32-bp deletion of the PTEN gene with susceptibility to metabolic syndrome

Mohammad Hashemi, Hamzeh Rezaei, Ebrahim Eskandari-Nasab, Mahmoud-Ali Kaykhaei, Mohsen Taheri
Pages: 342-346
Published online on: 08 November 2012

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Article

MYH rs3219476 and rs3219472 polymorphisms and risk of cholangiocarcinoma

Si-Hong You, Xiang Wang, Shu Huang, Min Wang, Guo-Zhong Ji, Jin-Rong Xia, Zhi-Ning Fan
Pages: 347-351
Published online on: 08 November 2012

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Journal Cover
February-2026 Volume 33 Issue 2

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

ISX promotes tumor migration and invasion in lung cancer by upregulating COL1A1 in vitro

Yihe Ma, Ye Chen, Yuhui Liang, Yun Huang, Miao Gong, Lifeng Tian, Xiaojun Xiao, Jingyan Liu, Qinmiao Huang
Article Number: 77
Published online on: 31 December 2025

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Article Open Access

Role and mechanism of miR‑222‑5p in endothelial cell apoptosis

Shimeng Wang, Boxin Zhao, Ying Cui, Lin Gui, Jingyao Fan, Lijuan Huang
Article Number: 76
Published online on: 31 December 2025

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Expression of Concern Open Access

[Expression of Concern] MicroRNA-29c inhibits proliferation and promotes apoptosis in non-small cell lung cancer cells by targeting VEGFA

Shijuan Zhan, Chunfeng Wang, Fangqing Yin
Article Number: 75
Published online on: 22 December 2025

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Melatonin induces autophagy in neuroblastoma by alleviating Pak2‑mediated endoplasmic reticulum stress

Qian-Qi Qiu, Na Zhang, Ying-Yi Xu, Jing-Wen Qin, Gao-Feng Yu, Xing-Rong Song
Article Number: 74
Published online on: 22 December 2025

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ST3Gal1 modulates intestinal barrier function and impacts human ulcerative colitis

Yin Tian, Yun Liu, Yangyang Shang, Lijian Ran, Li Liu, Rongquan Wang, Jun Ye
Article Number: 73
Published online on: 18 December 2025

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Mechanistic study of miR‑369‑3p in regulating the Wnt/β‑catenin signaling pathway via targeting SPTBN1 in inflammatory response and bone destruction of rheumatoid arthritis

Aihong Wu, Yuan Wang, Feifei Liu, Zhoufang Cao, Shuhui Du, Mengyu Sun
Article Number: 72
Published online on: 18 December 2025

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CACNB1 alleviates mepivacaine‑induced myocardial ischemia/reperfusion injury by promoting Nrf2 nuclear translocation

Qingbo Shao, Ji Zhang, Huaying Wang
Article Number: 71
Published online on: 17 December 2025

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Expression of Concern Open Access

[Expression of Concern] Effects of cullin 4B on the proliferation and invasion of human gastric cancer cells

Feng He, Xiu-Mei Cheng, Wen-Long Gu
Article Number: 70
Published online on: 17 December 2025

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Aggravated effects of human parvovirus B19 NS1 protein on bleomycin‑induced pulmonary fibrosis

Tsai-Ching Hsu, Chih-Chen Tzang, Chia-Wei Kuo, Zhi-Han Wen, Der-Yuan Chen, Bor-Show Tzang
Article Number: 69
Published online on: 16 December 2025

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Review Open Access

Advances regarding the mechanism of endoplasmic reticulum stress in diabetic kidney disease and pharmacological interventions (Review)

Pai Zhang, Yabin Cui, Chunyan Liu, Chengji Cui, Shoulin Zhang, Yue Zhang, Fan Li
Article Number: 68
Published online on: 16 December 2025

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Retraction Open Access

[Retracted] N‑Myc downstream‑regulated gene 2 suppresses the proliferation of T24 human bladder cancer cells via induction of oncosis

Jie Huang, Zhou Wu, Guangxiu Wang, Yingxian Cai, Minshan Cai, Yaozhang Li
Article Number: 67
Published online on: 15 December 2025

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Deciphering epigenetic regulation in cardiac developmental toxicity: Mechanisms and implications (Review)

Ziling Qin, Ranran Chen, Dianrong Song
Article Number: 66
Published online on: 11 December 2025

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Review Open Access

Gut microbiota as a multifaceted modulator of prostate cancer: Mechanistic insights, therapeutic opportunities and clinical challenges (Review)

Zhenming Hao, Yongqiang Xie, Ru Zhang, Hui Sang, Luxi Li, Yulin Liu, Jinbo Hu, Jijun Wang, Keqiang Chai, Qiang Zhao
Article Number: 65
Published online on: 11 December 2025

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Expression of Concern Open Access

[Expression of Concern] lncRNA FLVCR1‑AS1 drives colorectal cancer progression via modulation of the miR‑381/RAP2A axis

Yi Han, Xiaoyan Wang, Enqiang Mao, Boyong Shen, Liang Huang
Article Number: 64
Published online on: 10 December 2025

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Review Open Access

Influence and treatment of insulin receptor substrate/PI3K/Akt‑mediated insulin resistance in diabetes mellitus (Review)

Weikang Tang, Huixia Liu, Xuan Li, Siyao Deng, Changyu Gao
Article Number: 63
Published online on: 09 December 2025

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Retraction Open Access

[Retracted] Long non‑coding RNA ANRIL knockdown suppresses apoptosis and pro‑inflammatory cytokines while enhancing neurite outgrowth via binding microRNA‑125a in a cellular model of Alzheimer’s disease

Bingling Zhou, Lijuan Li, Xin Qiu, Jiashun Wu, Lei Xu, Wei Shao
Article Number: 62
Published online on: 08 December 2025

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Review Open Access

Mitophagy and oxidative stress in chronic kidney disease (Review)

Quwu Mushuo, Yihuai Tian, Jianchun Li, Yanqin Qiu, Hui Fan, Qiongdan Hu, Qiong Zhang
Article Number: 61
Published online on: 04 December 2025

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Article Open Access

ABCC9 knockdown attenuates isoproterenol‑induced myocardial hypertrophy by inhibiting the PI3K/AKT signaling pathway

Qian Peng, Rui Chang, Linlin Ma, Yanfei Li
Article Number: 60
Published online on: 04 December 2025

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Article

MeCP2 suppresses ferroptosis to drive EMT in retinal pigment epithelial cells: Implications for PVR pathogenesis

Sibei Guo, Yongya Zhang, Xue Li, Xueru Zhao, Yingjuan Liang, Xiaohua Li
Article Number: 59
Published online on: 04 December 2025

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Correction Open Access

[Corrigendum] Screening for implicated genes in colorectal cancer using whole‑genome gene expression profiling

Long-Ci Sun, Hai-Xin Qian
Article Number: 58
Published online on: 04 December 2025

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Article Open Access

Hyperoside prevents osteoporosis by activating the PI3K/AKT signaling pathway to inhibit oxidative stress and promote osteogenesis

Lirong Li, Huaidong Deng, Shabin Zhuan, Boyu Wu, Dawei Xiao
Article Number: 57
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Interference with Tim‑3 protein expression attenuates the invasion of clear cell renal cell carcinoma and aggravates anoikis

Muming Yu, Bin Lu, Yancun Liu, Ying Me, Lijun Wang, Hui Li
Article Number: 56
Published online on: 01 December 2025

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Article Open Access

Acetylshikonin induces ferroptosis via the lipid peroxidation pathway in osteosarcoma cells

Ji-Ying Chen, Guo-Shou Wang, Tsung-Ming Chang, Ju-Fang Liu
Article Number: 55
Published online on: 27 November 2025

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Review Open Access

Liver X receptor: A potential target for inflammatory bowel disease and colorectal cancer (Review)

Yingjie Li, Xiaoyan Fu, Meiwen Bai, Jiaqi Zhou, Jiatai Qiu, Hongxia Zhang, Shujuan Liang, Meifang Liu
Article Number: 54
Published online on: 27 November 2025

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Article Open Access

lncRNA NEAT1 promotes the proliferation of hemangioma cells by transcriptionally activating β‑catenin via enhancing H3K18 lactylation

Li Yu, Nian Zhou, Xiao-Liang Zhang, Xue-Jing Pang, Lu Xing, Yun-Jing Pu, Li Zhang, Jing-Nan Wu, Hong Shu
Article Number: 53
Published online on: 25 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑206 exerts anti‑oncogenic functions in esophageal squamous cell carcinoma by suppressing the c‑Met/AKT/mTOR pathway

Jin Zhang, Xianen Fa, Qingyong Zhang
Article Number: 52
Published online on: 25 November 2025

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March-2026 Volume 33 Issue 3

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Converting ‘cold’ to ‘hot’ hepatocellular carcinoma for improved immunotherapy (Review)

Ching-Hua Hsieh, Pei-Chin Chuang
Article Number: 93
Published online on: 15 January 2026

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Pathological mechanism of ferroptosis in a rat model of α‑naphthyl isothiocyanate‑induced chronic cholestasis

Zhen Guo, Jiaxuan Wang, Yiwen Wang, Xinzhu Liu, Yubing Xia, Ping Liu, Li Qi, Jia Liu, Xiaoning Wang
Article Number: 92
Published online on: 14 January 2026

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Correction Open Access

[Corrigendum] Role of hypoxia‑inducible factor‑1α and CD146 in epidermal growth factor receptor‑mediated angiogenesis in salivary gland adenoid cystic carcinom

Wei-Ming Wang, Zhi-Li Zhao, Wen-Feng Zhang, Yi-Fang Zhao, Lu Zhang, Zhi-Jun Sun
Article Number: 91
Published online on: 13 January 2026

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Klebsiella pneumoniae and pyogenic liver abscess: Emerging clinical threats, virulence mechanisms and therapeutic strategies (Review)

Gulam Mustafa Hasan, Taj Mohammad, Sobia Zaidi, Anas Shamsi, Sukhwinder Singh Sohal, Md. Imtaiyaz Hassan
Article Number: 90
Published online on: 13 January 2026

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Collagen III regulates the termination of liver regeneration by suppressing hepatocyte proliferation and promoting functional recovery

Haiyang Peng, Zhiyong Chen, Qiwei Zhang, Yuezhou Zhang, Peng Yang, Jianping Gong, Andong Zhao
Article Number: 89
Published online on: 13 January 2026

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Application of extracellular vesicles in the diagnosis and treatment of chronic obstructive pulmonary disease (Review)

Yixin Zhang, Tong Ren, Jianbo Xue, Yan Yu, Xianqiang Zhou, Xiaoyi Hu, Wenyi Yu, Zhancheng Gao, Cuiling Feng
Article Number: 88
Published online on: 13 January 2026

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Cigarette smoke combined with Klebsiella pneumoniae induce damage to the air‑blood barrier in chronic obstructive pulmonary disease rats via the MAPK/NF‑κB/IκBα pathway

Yange Tian, Kexin Xu, Ruilong Lu, Kangchen Li, Xuejie Shao, Yixi Liao, Yakun Zhao, Zhiguang Qiu, Haoran Dong, Xuefang Liu
Article Number: 87
Published online on: 12 January 2026

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Retraction Open Access

[Retracted] 8‑bromo‑7‑methoxychrysin induces apoptosis by regulating Akt/FOXO3a pathway in cisplatin‑sensitive and resistant ovarian cancer cells

Qing Ding, Yi Chen, Qing Zhang, Yanling Guo, Zhi Huang, Liqing Dai, Sudan Cao
Article Number: 86
Published online on: 12 January 2026

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Anxiety‑induced overactive bladder: The role of oxidative stress and NF‑κB signaling pathway with Hsp90 as a potential biomarker

Zhipeng Zhou, Lina Xu, Han Wu, Huaishan Hong
Article Number: 85
Published online on: 12 January 2026

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Article Open Access

Echinacoside alleviates asthenozoospermia by upregulating Sox5‑mediated transcriptional activation of the CatSper gene

Zi-Run Jin, Yong-Wei Huo, Bo-Heng Liu, Hong Tian, Shuo Yuan, Yue Tian, Ke Xi, Jie Cai, Hui Jiang, Yong Jiang, Guo-Gang Xing
Article Number: 84
Published online on: 12 January 2026

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Article Open Access

Artemisiae Scopariae Herba (Yinchen) suppresses ferroptosis in mice with osteoporosis via the Nrf2/Slc7a11/Gpx4 pathway

Pei Li, Xinyu Wan, Wenjie Li, Ding Cheng, Ying Yang, Yuhan Wang, Ruyuan Zhu, Yanjing Chen, Haixia Liu, Zhiguo Zhang
Article Number: 83
Published online on: 12 January 2026

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Review Open Access

Prolyl hydroxylase domain proteins: Localization, regulation, function and their role in erythropoiesis (Review)

Yan Hou, Zhao-Hua Zhang, Wen-Qian Li, Guo-Xiong Han, Kuo Shen, You-Bang Xie
Article Number: 82
Published online on: 12 January 2026

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Review Open Access

Therapeutic potential of saponins for allergic rhinitis: Molecular mechanisms and clinical perspectives (Review)

Bing-Yu Liang, Zi-Yue Fu, Fen-Fen Li, Ping-Ting Zhou, Zi-Hui Xie, Ke Han, Yan-Xun Han, Shan-Wen Chen, Yi Zhao, Hai-Feng Pan, Ye-Hai Liu, Yu-Chen Liu
Article Number: 81
Published online on: 07 January 2026

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Interleukin‑6 and ischemic stroke: From mechanisms to clinical prospects (Review)

Xinyue Wang, Xiaohang Zhang, Jianing Lin, Ping Lin
Article Number: 80
Published online on: 05 January 2026

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Article Open Access

Preliminary exploration of the putative function of SF3A2 in clear cell renal cell carcinoma

Ru Chen, Jie Xu
Article Number: 79
Published online on: 05 January 2026

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Retraction Open Access

[Retracted] TIPE‑2 suppresses growth and aggressiveness of hepatocellular carcinoma cells through downregulation of the phosphoinositide 3‑kinase/AKT signaling pathway

Lin Wang, Chen Chen, Shuzhi Feng, Jianli Tian
Article Number: 78
Published online on: 05 January 2026

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