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International Journal of Molecular Medicine
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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
February 2009 Volume 23 Issue 2

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review

The longevity assurance homologue of yeast lag1 (Lass) gene family (Review)

Andreas Teufel, Thorsten Maass, Peter R. Galle, Nasir Malik
Pages: 135-140
Published online on: 01 February 2009

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Review

WASP and WAVE proteins: Vital intrinsic regulators of cell motility and their role in cancer (Review)

Herman S. Fernando, Howard G. Kynaston, Wen G. Jiang
Pages: 141-148
Published online on: 01 February 2009

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Article

Dystrophin-glycoprotein complex and vinculin-talin-integrin system in human adult cardiac muscle

Giuseppe Anastasi, Giuseppina Cutroneo, Roberto Gaeta, Debora Di Mauro, Alba Arco, Angela Consolo, Giuseppe Santoro, Fabio Trimarchi, Angelo Favaloro
Pages: 149-159
Published online on: 01 February 2009

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Article Open Access

Molecular dissection of human oncostatin M-mediated signal transductions through site-directed mutagenesis

Haiyan Liu, Cristina Fenollar-Ferrer, Aiqin Cao, Claudio Anselmi, Paolo Carloni, Jingwen Liu
Pages: 161-172
Published online on: 01 February 2009

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Article

Remodeling of the human endometrial epithelium is regulated by laminin and type IV collagen

Tetsuji Tanaka, Chunlian Wang, Naohiko Umesaki
Pages: 173-180
Published online on: 01 February 2009

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Article

Humoral immunity responses against EGFR-positive tumor cells induced by xenogeneic EGFR expressed in the yeast Pichia pastoris

Fang Fang, Ping Chen, Xian-cheng Chen, Jiong Li, Yan-jun Wen, Yu-quan Wei
Pages: 181-188
Published online on: 01 February 2009

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Article

Astragalus saponins induce apoptosis via an ERK-independent NF-κB signaling pathway in the human hepatocellular HepG2 cell line

Kathy Ka-Wai Auyeung, Pui-Ching Law, Joshua Ka-Shun Ko
Pages: 189-196
Published online on: 01 February 2009

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Article

Oligomeric proanthocyanidins from grape seeds effectively inhibit ultraviolet-induced melanogenesis of human melanocytes in vitro

Shao-Xia Zi, Hui-Jun Ma, You Li, Wen Liu, Qing-Qi Yang, Guang Zhao, Shi Lian
Pages: 197-204
Published online on: 01 February 2009

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Article

Dyclonine and alverine citrate enhance the cytotoxic effects of proteasome inhibitor MG132 on breast cancer cells

Donghong Ju, Xiaogang Wang, Youming Xie
Pages: 205-209
Published online on: 01 February 2009

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Article

Antiproliferative effects of dehydrocostuslactone through cell cycle arrest and apoptosis in human ovarian cancer SK-OV-3 cells

Eun Jeong Choi, Woong Shick Ahn
Pages: 211-216
Published online on: 01 February 2009

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Article

Polymorphisms of the ApoE, HSD3B1, IL-1β and p53 genes are associated with the development of early uremic complications in diabetic patients: Results of a DNA resequencing array study

Dominika Szoke, Bela Molnar, Norbert Solymosi, Karoly Racz, Peter Gergics, Bernadett Blasko, Barna Vasarhelyi, Adam Vannay, Yvette Mandy, Gergely Klausz, Zsofia Gyulai, Orsolya Galamb, Sandor Spisak, Bernadett Hutkai, Aniko Somogyi, Klara Berta, Andras Szabo, Tivadar Tulassay, Zsolt Tulassay
Pages: 217-227
Published online on: 01 February 2009

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Article Open Access

Establishment of an immortalized human extravillous trophoblast cell line by retroviral infection of E6/E7/hTERT and its transcriptional profile during hypoxia and reoxygenation

Hiroko Omi, Aikou Okamoto, Takashi Nikaido, Mitsuyoshi Urashima, Rie Kawaguchi, Nagayoshi Umehara, Kentaro Sugiura, Misato Saito, Tohru Kiyono, Tadao Tanaka
Pages: 229-236
Published online on: 01 February 2009

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Article

Danazol enhances Fas-mediated apoptosis in human endometrial epithelial cells within normal physiology

Tetsuji Tanaka, Naohiko Umesaki
Pages: 237-243
Published online on: 01 February 2009

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Article

Chromosomal characterization and localization of the NAD+-dependent histone deacetylase gene sirtuin 1 in the mouse

Ulrich Mahlknecht, Susanne Voelter-Mahlknecht
Pages: 245-252
Published online on: 01 February 2009

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Article

Alterations in CD44 isoforms and HAS expression in human articular chondrocytes during the de- and re-differentiation processes

Christian Albrecht, Werner Schlegel, Peter Eckl, Tamara Jagersberger, Kambis Sadeghi, Angelika Berger, Vilmos Vécsei, Stefan Marlovits
Pages: 253-259
Published online on: 01 February 2009

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Article

Expression of angiogenesis inhibitors in human bladder cancer may explain rapid metastatic progression after radical cystectomy

Wolf-Dietrich C. Beecken, Tobias Engl, Dietger Jonas, Roman A. Blaheta
Pages: 261-266
Published online on: 01 February 2009

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Article

Tacrolimus but not cyclosporine A enhances FGF-2-induced VEGF release in osteoblasts

Junichi Yamauchi, Shinji Takai, Rie Matsushima-Nishiwaki, Seiji Adachi, Chiho Minamitani, Hideo Natsume, Jun Mizutani, Takanobu Otsuka, Jun Takeda, Atsushi Harada, Osamu Kozawa, Haruhiko Tokuda
Pages: 267-272
Published online on: 01 February 2009

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Article

Transcriptional and translational modulation of KAI1 expression in ductal carcinoma of the breast and the prognostic significance

Fraz A. Malik, Andrew J. Sanders, Anthony Douglas Jones, Robert E. Mansel, Wen G. Jiang
Pages: 273-278
Published online on: 01 February 2009

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Article

Angiopoietin-1 reduces vascular endothelial growth factor-induced brain endothelial permeability via upregulation of ZO-2

Sae-Won Lee, Woo Jean Kim, Hyoung-Oh Jun, Yoon Kyung Choi, Kyu-Won Kim
Pages: 279-284
Published online on: 01 February 2009

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Article

Predictive value of survivin alternative transcript expression in locally advanced breast cancer patients treated with neoadjuvant chemotherapy

Romain Boidot, Frédérique Vegran, Sarab Lizard-Nacol
Pages: 285-291
Published online on: 01 February 2009

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Article

Cementum attachment protein/protein-tyrosine phosphotase-like member A is not expressed in teeth

Christof Schild, Michael Beyeler, Niklaus P. Lang, Beat Trueb
Pages: 293-296
Published online on: 01 February 2009

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Article

The estrogen 17β-estradiol and phytoestrogen genistein mediate differential effects on osteoblastic NF-κB activity

Masayoshi Yamaguchi, M. Neale Weitzmann
Pages: 297-301
Published online on: 01 February 2009

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Journal Cover
May-2026 Volume 57 Issue 5

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

Macrophage SH3 domain‑containing GRB2‑like protein B1 is required for Rab7‑mediated mitophagy in inflammation during sea water drowning acute lung injury

Hongjuan Ning, Jingyu Deng, Yongheng Gao, Wei Zhang, Jian Chen, Xian Guo, Faguang Jin
Article Number: 138
Published online on: 24 March 2026

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Article Open Access

Deferoxamine mitigates neuronal loss following spinal cord injury via ferroptosis inhibition and Nrf2/HO‑1 pathway activation

Ziqian Ma, Xinwei Zhang, Tao Liu, Yan Zhang, Guanghao Li, Xin Yuan, Benqiang Tang, Hangyi Zhao, Liang Liu, Xueming Chen
Article Number: 137
Published online on: 23 March 2026

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Review Open Access

USP10 deubiquitinase: Physiological function, diseases and therapeutic target (Review)

Linlin Zhang, Huajing Sun, Zifan Wang, Zhimei Wang, Qiang Mu, Yukun Liu
Article Number: 136
Published online on: 23 March 2026

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Article Open Access

Siglec‑15 dysregulation and its therapeutic implications in new‑onset type 1 diabetes 

Heming Guo, Yunwen Tao, Sicheng Li, Ying Gu, Yiting Huang, Chen Fang, Ji Hu
Article Number: 135
Published online on: 20 March 2026

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Article Open Access

ZEB1 maintains mitochondrial fission and macrophage efferocytosis by restraining MFN2, thereby limiting inflammation and improving tendon‑bone healing

Yan Zhao, Yuankai Zhang, Tian Lei, Shangqing Zhang, Kai Nan, Xin Zhang, Li-Hong Fan
Article Number: 134
Published online on: 19 March 2026

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Review Open Access

Targeting pyroptosis in renal fibrosis: From molecular mechanisms to therapeutic horizons (Review)

Yihuai Tian, Quwu Mushuo, Hui Fan, Hongwei Su, Jianchun Li, Qiong Zhang
Article Number: 133
Published online on: 19 March 2026

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Expression of Concern Open Access

[Expression of Concern] Fasudil, a Rho‑associated protein kinase inhibitor, attenuates retinal ischemia and reperfusion injury in rats

Haishan Song, Dianwen Gao
Article Number: 132
Published online on: 18 March 2026

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Review Open Access

Epigenetic regulation in a high-sugar environment (Review)

Huili Zhou, Xinhe Lv, Yu Liang, Dehai Yu, Wanning Wang
Article Number: 131
Published online on: 17 March 2026

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Review Open Access

The roles and heterogeneity of CD8+ T cells in inflammatory bowel disease: A narrative review of insights from single‑cell transcriptomics (Review)

Rui Zhong, Jing Guo, Wujie Ye, Zhihui Deng, Huangan Wu, Qin Qi, Guona Li, Lu Zhu, Yan Huang, Luyi Wu
Article Number: 130
Published online on: 17 March 2026

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Review Open Access

Mechanism of action and clinical application of autophagy in multiple sclerosis (Review)

Dongmei Wang, Qizhi Fu, Ying Zhao, Guangda Li, Yongjie Bai, Yang Yang, Hongna Song, Mingwei Wang, Hua Fan
Article Number: 129
Published online on: 17 March 2026

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Expression of Concern Open Access

[Expression of Concern] Insulin‑dependent diabetes mellitus decreases osteoblastogenesis associated with the inhibition of Wnt signaling through increased expression of Sost and Dkk1 and inhibition of Akt activation

Mamiko Hie, Natsumi Iitsuka, Tomoyo Otsuka, Ikuyo Tsukamoto
Article Number: 128
Published online on: 16 March 2026

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Review Open Access

Mechanotransduction and its impact on regenerative medicine in orthopedic rehabilitation (Review)

Baohui Wang, Xueqin Zeng, Huajian Liu, Liang Li, Tao Lei, Yafeng Li, Qing Fang, Yi Cao, Bo Dong
Article Number: 127
Published online on: 13 March 2026

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Article Open Access

4‑Acetylantrocamol LT3 suppresses colorectal cancer growth and metastasis via PI3K/AKT and MAPK pathway modulation

Kuen-Tze Lin, Yu-Chieh Hsieh, Pi-Kai Chang, Chih-Wei Lai, Shih-Yu Lee, I-Chuan Yen
Article Number: 126
Published online on: 13 March 2026

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Review Open Access

Roles of ubiquitin‑specific peptidase 22 in cellular fate: From embryonic survival to tissue repair, inflammation and metabolism (Review)

Jia-Nan Xiang, Chen-Yang Zhou, Yu-Di Zhao, Xiao Xu, Sun-Bin Ling
Article Number: 125
Published online on: 12 March 2026

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Review Open Access

m6A in adipose tissue inflammation: A novel regulator of obesity and metabolic diseases (Review)

Xiaoting Yang, Xiaodan Wang, Haojun Tang, Shuangxi Tu, Kai Yin, Xiao Zhu
Article Number: 124
Published online on: 12 March 2026

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Expression of Concern Open Access

[Expression of Concern] Visfatin/PBEF/Nampt induces EMMPRIN and MMP‑9 production in macrophages via the NAMPT‑MAPK (p38, ERK1/2)‑NF‑κB signaling pathway

Yuqi Fan, Shu Meng, Yue Wang, Jiatian Cao, Changqian Wang
Article Number: 123
Published online on: 12 March 2026

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Article Open Access

IL‑37/IL‑1R8 blocks keratinocyte acantholysis via suppressing ADAM17/EGFR

Fengxia Hu, Wenjing Chen, Qian Wang, Xiaoyu Zhang, Fuyang Xiao, Jinying Zhang, Junqin Liang
Article Number: 122
Published online on: 12 March 2026

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Review Open Access

Reactive oxygen species in fetal growth restriction mechanisms and therapeutic directions (Review)

Di Cheng, Songbin Yang, Cuilan Wang, Kefeng Fan, Fengchun Gao, Qian Sun
Article Number: 121
Published online on: 12 March 2026

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Research progress on the molecular mechanisms of tanshinone IIA in the treatment of cardiovascular and cerebrovascular diseases (Review)

Wen Pei, Ping Lu, Chenhuan Ding, Ying Li, Yong Li
Article Number: 120
Published online on: 12 March 2026

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Ferritin in ferroptosis: Implications for neurodegenerative diseases (Review)

Wenjing Chen, Heng Tian, Ran Wei, Xiaomei Chen, Yiwen Jia
Article Number: 119
Published online on: 12 March 2026

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Correction Open Access

[Corrigendum] Ursolic acid protects against cisplatin‑induced ototoxicity by inhibiting oxidative stress and TRPV1‑mediated Ca2+‑signaling  

Yang Di, Tao Xu, Yuan Tian, Tingting Ma, Donghao Qu, Yan Wang, Yuhan Lin, Dongyan Bao, Li Yu, Shuangyue Liu, Aimei Wang
Article Number: 118
Published online on: 09 March 2026

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Article Open Access

HELLS inhibits autophagy‑dependent ferroptosis in nasopharyngeal carcinoma by modulating the Nrf2/HO‑1/GPX4 pathway

Chengxun Jin, Jinqiu Li, Siqi Han, Chaoluomeng Bai, Jingpu Yang, Zonggui Wang
Article Number: 117
Published online on: 09 March 2026

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Expression of Concern Open Access

[Expression of Concern] Inhibitory effect of curcumin on angiogenesis in ectopic endometrium of rats with experimental endometriosis

Ying Zhang, Hong Cao, Yue-Yue Hu, Hua Wang, Chang-Jun Zhang
Article Number: 116
Published online on: 09 March 2026

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Article Open Access

Propofol upregulates MFG‑E8 in BV2 cells to inhibit pyroptosis mediated by the NF‑κB/NLRP3 pathway, thereby ameliorating ischemic‑reperfusion neuronal injury

Shewei Guo, Yingwei Zhen, Guosheng Zhou, Zhihua Zhao
Article Number: 115
Published online on: 05 March 2026

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Article Open Access

Exosomal circ0000549 promotes MNNG‑induced gastric cancer through miR‑15b‑5p/KIF1B

Zhaofeng Liang, Zihan Gao, Yue Zhang, Jiajia Song, Hui Qian, Xuezhong Xu
Article Number: 114
Published online on: 04 March 2026

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Expression of Concern Open Access

[Expression of Concern] Syringin prevents cardiac hypertrophy induced by pressure overload through the attenuation of autophagy  

Fangfang Li, Ning Zhang, Qingqing Wu, Yuan Yuan, Zheng Yang, Mengqiao Zhou, Jinxiu Zhu, Qizhu Tang
Article Number: 113
Published online on: 04 March 2026

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Review Open Access

Treatment of pulmonary fibrosis: From disease mechanisms to future novel therapies (Review)

Sen Lu, Yunfei Liu, Xiaohua Li, Qipeng Yao
Article Number: 112
Published online on: 03 March 2026

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Review Open Access

Research progress in single‑cell omics technologies for kidney disease (Review)

Jia Xu, Ziwei Chen, Shengyao Li, Xiaoya Wang, Ming Chen
Article Number: 111
Published online on: 03 March 2026

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Review Open Access

CLDN7: Epithelial gatekeeper from physiology to pathology‑roles in cancer and epithelial‑related diseases (Review)

Xiuping Lai, Yan Yan, Lu Sun, Zili Lei, Yanhong Yang
Article Number: 110
Published online on: 03 March 2026

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Review Open Access

Dynamic regulation and targeted intervention of neutrophils in hepatic ischemia‑reperfusion injury (Review)

Sen Lu, Jiale Tong, Jing Jiang, Qin Zhang, Youjin Huang
Article Number: 109
Published online on: 03 March 2026

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Review Open Access

The dual role of the crosstalk between autophagy and ferroptosis in lung cancer treatment: Advances in mechanisms and therapeutic strategies (Review)

Yingying Zhang, Ruxin Shen
Article Number: 108
Published online on: 02 March 2026

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Review Open Access

Mechanistic insights into inflammatory cytokines in adenomyosis‑induced infertility (Review)

Bojiao Yang, Feng Li, Guimao Cao, Mingtu Nuo, Yaxin Shi, Zilu Wang, Jing Jia, Wei Shi, Zhiyong Liu
Article Number: 107
Published online on: 02 March 2026

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Correction Open Access

[Corrigendum] Astragaloside IV promotes the proliferation and migration of osteoblast‑like cells through the hedgehog signaling pathway

Li-Hua Guo, Yu Cao, Run-Tao Zhuang, Yan Han, Jun Li
Article Number: 106
Published online on: 02 March 2026

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Journal Cover
June-2026 Volume 57 Issue 6

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Crosstalk between autophagy and ferroptosis in liver diseases (Review)

Yanming Wei, Kun Zhou, Yuerui Su, Zhihua Luan, Pengcheng Li, Yinxia Chang, Bo Han, Huifang Li, Yuanbiao Qiao, Jinhong Ren
Article Number: 142
Published online on: 26 March 2026

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Article Open Access

circOMA1 delivered by exosomes regulates DRD2‑mediated prolactinoma resistance

Qing Rao, Dimin Zhu, Zongming Wang, Shaolin Zhang, Xueli Li, Shashikiran Tagilapalli, Nan Wang, Weiyu Hu, Wenli Chen, Yonghong Zhu
Article Number: 141
Published online on: 26 March 2026

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Expression of Concern Open Access

[Expression of Concern] Involvement of Cyr61 in the growth, invasiveness and adhesion of esophageal squamous cell carcinoma cells

Jian-Jun Xie, Li-Yan Xu, Yang-Min Xie, Ze-Peng Du, Cai-Hua Feng, Hui Dong, En-Min Li
Article Number: 140
Published online on: 24 March 2026

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Article Open Access

Novel Hsp90 inhibitor JD‑02 inhibits HSV‑1 infection via the Raf/MEK/ERK signaling pathway

Yexuan Zhu, Xiaohui Wang, Jiaying Lin, Xiao Wang, Kai Zheng, Zhe Ren, Ji Xiao, Yifei Wang
Article Number: 139
Published online on: 24 March 2026

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