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Molecular Medicine Reports
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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
July-2014 Volume 10 Issue 1

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

DNA methylation profiles in ovarian cancer: Implication in diagnosis and therapy (Review)

Ourania Koukoura, Demetrios A. Spandidos, Alexandros Daponte, Stavros Sifakis
Pages: 3-9
Published online on: 08 May 2014

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Article Open Access

Monoglucosyl‑rutin as a potential radioprotector in mammalian cells

Shigeaki Sunada, Hiroshi Fujisawa, Ian M. Cartwright, Junko Maeda, Colleen A. Brents, Kazue Mizuno, Yasushi Aizawa, Takamitsu A. Kato, Mitsuru Uesaka
Pages: 10-14
Published online on: 24 April 2014

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Article Open Access

Atoh1 expression levels define the fate of rat cochlear nonsensory epithelial cells in vitro

Wen‑Wei Luo, Juan‑Mei Yang, Zhao Han, Ya‑Sheng Yuan, Hai‑Bin Sheng, Xiang Liu, Fang‑Lu Chi
Pages: 15-20
Published online on: 30 April 2014

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Article Open Access

Induction of E-cadherin+ human amniotic fluid cell differentiation into oocyte-like cells via culture in medium supplemented with follicular fluid

Te Liu, Yongyi Huang, Yanzhen Bu, Yanhui Zhao, Gang Zou, Zhixue Liu
Pages: 21-28
Published online on: 29 April 2014

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Article Open Access

Tetramethylpyrazine promotes the proliferation and migration of brain endothelial cells

Mingshun Zhang, Feng Gao, Fengmeng Teng, Chunbing Zhang
Pages: 29-32
Published online on: 24 April 2014

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Article Open Access

Colorectal polyp model established by transplacental BMP4 RNAi

Xin Jin, Zhongmei Chen, Li Xiang, Qing Luo, Zhenghua Guo, Xionghui Ding, Xianqing Jin
Pages: 33-38
Published online on: 07 May 2014

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Article Open Access

Epithelial‑mesenchymal transition and apoptosis of renal tubular epithelial cells are associated with disease progression in patients with IgA nephropathy

Junxia Yao, Zunji Ke, Xiaoyan Wang, Feng Peng, Bin Li, Renliang Wu
Pages: 39-44
Published online on: 24 April 2014

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Article Open Access

Complement anaphylatoxin C4a inhibits C5a-induced neointima formation following arterial injury

Yan Zhao, Heng Xu, Wenhui Yu, Bao-Dong Xie
Pages: 45-52
Published online on: 24 April 2014

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Article Open Access

Role and mechanism of Twist1 in modulating the chemosensitivity of FaDu cells

Sumei Lu, Liang Yu, Yakui Mu, Juke Ma, Jiajun Tian, Wei Xu, Haibo Wang
Pages: 53-60
Published online on: 06 May 2014

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Article Open Access

Hyperoxia arrests pulmonary development in newborn rats via disruption of endothelial tight junctions and downregulation of Cx40

Chong Li, Jianhua Fu, Hongyu Liu, Haiping Yang, Li Yao, Kai You, Xindong Xue
Pages: 61-67
Published online on: 28 April 2014

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Article Open Access

Multiple-locus variable number of tandem repeats analysis of Salmonella enterica serotype paratyphi A from Yuxi and comparison with isolates from the Chinese Medical Culture Collection Center

Yingbo Yao, Xiaoyan Cui, Qingshan Chen, Xinrong Huang, Bradley Elmore, Qing Pan, Shukun Wang, Jie Liu
Pages: 68-74
Published online on: 24 April 2014

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Article Open Access

An interspecies conserved motif of the mouse immune system-released activating agent (ISRAA) induces proliferative effects on human cells

Safa Taha, Mohamed Dahmani Fathallah, Moiz Bakhiet
Pages: 75-81
Published online on: 08 May 2014

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Article Open Access

KNDC1 knockdown protects human umbilical vein endothelial cells from senescence

Chunyan Zhang, Yong-Zhan Zhen, Ya-Jun Lin, Jiang Liu, Jie Wei, Rong Xu, Gang Hu
Pages: 82-88
Published online on: 30 April 2014

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Article

Cucurbitacin B inhibits growth and induces apoptosis through the JAK2/STAT3 and MAPK pathways in SH‑SY5Y human neuroblastoma cells

Qian Zheng, Yunyi Liu, Weiwei Liu, Fengyun Ma, Yi Zhou, Mingjie Chen, Junli Chang, Yuesheng Wang, Guangxiao Yang, Guangyuan He
Pages: 89-94
Published online on: 24 April 2014

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Article

Application of two-dimensional electrophoresis and mass spectrometry to screen endometriosis‑related proteins

Hanikezi Tuerxun, Yanmei Zhang, Fei Ji, Aixingzi Aili, Xinhua Yang, Yan Ding
Pages: 95-100
Published online on: 15 April 2014

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Article

Protective effect of resveratrol against acute lung injury induced by lipopolysaccharide via inhibiting the myd88‑dependent Toll-like receptor 4 signaling pathway

Zhuo Zhang, Ni Chen, Jin‑Bo Liu, Jian‑Bo Wu, Jing Zhang, Ying Zhang, Xian Jiang
Pages: 101-106
Published online on: 09 May 2014

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Article

Involvement of Rac in thromboxane A2‑induced human platelet activation: Regulation of sCD40 ligand release and PDGF‑AB secretion

Yasunari Kageyama, Tomoaki Doi, Rie Matsushima‑Nishiwaki, Yuko Iida, Shigeru Akamatsu, Akira Kondo, Gen Kuroyanagi, Naohiro Yamamoto, Jun Mizutani, Takanobu Otsuka, Haruhiko Tokuda, Hiroki Iida, Osamu Kozawa, Shinji Ogura
Pages: 107-112
Published online on: 15 April 2014

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Article

Co‑expression network analysis of differentially expressed genes associated with metastasis in prolactin pituitary tumors

Wei Zhang, Zhenle Zang, Yechun Song, Hui Yang, Qing Yin
Pages: 113-118
Published online on: 15 April 2014

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Article

Analysis of differentially expressed genes between rheumatoid arthritis and osteoarthritis based on the gene co‑expression network

Qing‑You Lu, Qing‑Hui Han, Xia Li, Zeng‑Chun Li, Yu‑Tao Pan, Lin Liu, Qing‑Ge Fu
Pages: 119-124
Published online on: 24 April 2014

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Article

Suppressive effect of microRNA-126 on oral squamous cell carcinoma in vitro

Xiaolun Yang, Hanjiang Wu, Tianyou Ling
Pages: 125-130
Published online on: 24 April 2014

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Article

Prognostic significance of nemo‑like kinase in nasopharyngeal carcinoma

Size Chen, Zhijian Ma, Xuemei Chen, Jiren Zhang
Pages: 131-136
Published online on: 28 April 2014

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Article

Small interfering RNA targeting ILK inhibits EMT in human peritoneal mesothelial cells through phosphorylation of GSK‑3β

Lingrong Luo, Hong Liu, Zheng Dong, Lin Sun, Youming Peng, Fuyou Liu
Pages: 137-144
Published online on: 17 April 2014

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Article

Identification of microRNAs involved in growth arrest and cell death in hydrogen peroxide-treated human dermal papilla cells

Ok-Yeon Kim, Hwa Jun Cha, Kyu Joong Ahn, In-Sook An, Sungkwan An, Seunghee Bae
Pages: 145-154
Published online on: 16 April 2014

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Article

microRNA‑145 inhibits osteosarcoma cell proliferation and invasion by targeting ROCK1 Retraction in /10.3892/mmr.2022.12790

Pengfei Lei, Jie Xie, Long Wang, Xucheng Yang, Zixun Dai, Yihe Hu
Pages: 155-160
Published online on: 28 April 2014

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Article

MicroRNA‑21 regulation of the progression of viral myocarditis to dilated cardiomyopathy

Hong‑Fei Xu, Yu‑Jie Ding, Zhi‑Xiang Zhang, Zu‑Feng Wang, Cheng‑Liang Luo, Bei‑Xu Li, Yi‑Wen Shen, Lu‑Yang Tao, Zi‑Qin Zhao
Pages: 161-168
Published online on: 02 May 2014

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Article

Knockdown of IRX2 inhibits osteosarcoma cell proliferation and invasion by the AKT/MMP9 signaling pathway

Tielong Liu, Weiwei Zhou, Fei Zhang, Guodong Shi, Honglin Teng, Jianru Xiao, Yan Wang
Pages: 169-174
Published online on: 07 May 2014

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Article

Clinical and pathological features of patients with nemaline myopathy

Xi Yin, Chuan Qiang Pu, Qian Wang, Jie Xiao Liu, Yan Ling Mao
Pages: 175-182
Published online on: 24 April 2014

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Article

Tumoricidal activity of combining the agonistic DR5 antibody D-6 with cisplatin in C30 cisplatin‑resistant ovarian cancer in vitro and in vivo

Yan Huang, Baoquan Liang, Qin Jiang, Chen Chen, Kun Yang, Chunmei Li, Ai Zheng
Pages: 183-190
Published online on: 28 April 2014

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Article

Prognostic value of PPM1D in 800 gastric cancer patients

Dan Ma, Chao-Jun Zhang, Zu-Lin Chen, Hua Yang
Pages: 191-194
Published online on: 24 April 2014

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Article

Impact of estrogen-related receptor α on the biological characteristics of rat mandibular condylar chondrocytes

Xin Chen, Chuan Cai, Jing Liu, Li Wen, Xi Wang, Yin Ding
Pages: 195-202
Published online on: 02 May 2014

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Article

Activation of STAT5 contributes to proliferation in U87 human glioblastoma multiforme cells

Cui Feng, Shouqiang Cao
Pages: 203-210
Published online on: 08 May 2014

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Article

Sanguinarine protects against pressure overload‑induced cardiac remodeling via inhibition of nuclear factor-κB activation

Wei Deng, Yi Fang, Yuan Liu, Heng Zhou, Zhihong Cheng, Yang Zhang, Di Sun, Mengying He, Yafen Lin, Rui Zhang, Jieyu Zhang, Wei Li, Qizhu Tang
Pages: 211-216
Published online on: 02 May 2014

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Article

Gene profiling in the dynamic regulation of the lifespan of the myelin sheath structure in the optic nerve of rats

Fang Xie, Han Fu, Jiu‑Cong Zhang, Xue‑Feng Chen, Xiao‑Liang Wang, Jun Chen
Pages: 217-222
Published online on: 09 May 2014

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Article

Expression of microRNA-26b, an obesity-related microRNA, is regulated by free fatty acids, glucose, dexamethasone and growth hormone in human adipocytes

Guangfeng Xu, Chunmei Shi, Chenbo Ji, Guixian Song, Ling Chen, Lei Yang, Yaping Zhao, Xirong Guo
Pages: 223-228
Published online on: 02 May 2014

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Article

Identification of the typical miRNAs and target genes in hepatocellular carcinoma

Keqiang Han, Jing Li, Hongzhi Zhao, Ping Liang, Xiaobing Huang, Lu Zheng, Yuming Li, Tonghan Yang, Liang Wang
Pages: 229-235
Published online on: 28 April 2014

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Article

Th17 cells are associated with the Th1/Th2‑cell balance during Echinococcus multilocularis infection

Xiumin Ma, Liang Wang, Hui Zhao, Nannan Pang, Fengbo Zhang, Tao Jiang, Xuelei Liu, Wulamu Mamuti, Hao Wen, Jianbing Ding
Pages: 236-240
Published online on: 24 April 2014

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Article

RNA‑seq analysis of synovial fibroblasts in human rheumatoid arthritis

Xiuhui Wang, Shengli Xia, Beigang Fu
Pages: 241-247
Published online on: 24 April 2014

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Article

Effect of Gua Lou Gui Zhi decoction on focal cerebral ischemia‑reperfusion injury through regulating the expression of excitatory amino acids and their receptors

Xianwen Chen, Huang Li, Mingqing Huang, Mei Huang, Wei Xu, Kedan Chu, Lidian Chen, Yuqin Zhang
Pages: 248-254
Published online on: 28 April 2014

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Article

Localization and expression patterns of prolactin‑like protein J in mouse testis

Qiaozhen Yang, Jie Hao, Miao He, Maoxin Chen, Gang Li
Pages: 255-261
Published online on: 07 May 2014

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Article

Lycopene inhibits neointimal hyperplasia through regulating lipid metabolism and suppressing oxidative stress

Min Mao, Han Lei, Qing Liu, Rui He, Zhong Zuo, Nan Zhang, Chao Zhou
Pages: 262-268
Published online on: 24 April 2014

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Article

Theophylline improves lipopolysaccharide-induced alveolarization arrest through inflammatory regulation

Hua He, Fei Chen, Wensi Ni, Jianhui Li, Yongjun Zhang
Pages: 269-275
Published online on: 24 April 2014

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Article

Peroxisome proliferator-activated receptor γ ligands inhibit VEGF-mediated vasculogenic mimicry of prostate cancer through the AKT signaling pathway

Liang Qin, Ye Ren, An-Min Chen, Feng-Jing Guo, Fei Xu, Chen Gong, Peng Cheng, Yu Du, Hui Liao
Pages: 276-282
Published online on: 29 April 2014

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Article

miR‑20a is an independent prognostic factor in colorectal cancer and is involved in cell metastasis

Guang‑Jun Zhang, Yu Li, He Zhou, Hua‑Xu Xiao, Tong Zhou
Pages: 283-291
Published online on: 15 April 2014

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Article

microRNAs mediate oleic acid-induced acute lung injury in rats using an alternative injury mechanism

Sang Mook Lee, Hyunsoo Choi, Geumjin Yang, Ki Cheol Park, Sikyoung Jeong, Sungyoup Hong
Pages: 292-300
Published online on: 15 April 2014

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Article

Pingyangmycin stimulates apoptosis in human hemangioma‑derived endothelial cells through activation of the p53 pathway

Jun‑Bo Tu, Quan‑Yan Li, Fei Jiang, Xiao‑Yi Hu, Rui‑Zhao Ma, Qiang Dong, Hao Zhang, Parukjan Pattar, Shi‑Xian Li
Pages: 301-305
Published online on: 24 April 2014

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Article

Anti-fibrotic effects of specific-siRNA targeting of the receptor for advanced glycation end products in a rat model of experimental hepatic fibrosis

Xiao-Gang Cai, Jin-Rong Xia, Wei-Dong Li, Feng-Lin Lu, Juan Liu, Qin Lu, Hong Zhi
Pages: 306-314
Published online on: 02 May 2014

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Article

microRNA-200c downregulates XIAP expression to suppress proliferation and promote apoptosis of triple-negative breast cancer cells

Yi Ren, Xuedong Han, Kun Yu, Su'an Sun, Linlin Zhen, Zhi Li, Shui Wang
Pages: 315-321
Published online on: 08 May 2014

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Article

Fms-related tyrosine kinase 3 ligand promotes proliferation of placenta amnion and chorion mesenchymal stem cells in vitro

Fang Li, Yunyun Xu, Xiaoxia Xu, Biao Xu, Juan Zhao, Xueguang Zhang
Pages: 322-328
Published online on: 08 May 2014

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Article

Generation of liver-specific TGF-α and c-Myc-overexpressing fibroblasts for future creation of a liver cancer porcine model

Jeeyoung Kim, Huijeong Ahn, Heung-Myong Woo, Eunsong Lee, Geun-Shik Lee
Pages: 329-335
Published online on: 07 May 2014

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Article

AP‑4 predicts poor prognosis in non‑small cell lung cancer

Hai Gong, Shaorong Han, Hui Yao, Hui Zhao, Yanming Wang
Pages: 336-340
Published online on: 02 May 2014

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Article

Inhibition of invasion and epithelial-mesenchymal transition of human breast cancer cells by hydrogen sulfide through decreased phospho-p38 expression

Min Lv, Yan Li, Ming-Hua Ji, Ming Zhuang, Jin-Hai Tang
Pages: 341-346
Published online on: 17 April 2014

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Article

Therapeutic effects of sorafenib on the A549/DDP human lung adenocarcinoma cell line in vitro

Xiang‑Qi Chen, Yu‑Lan Wang, Zhi‑Ying Li, Ting‑Yan Lin
Pages: 347-352
Published online on: 24 April 2014

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Article

Signal transduction mechanism of the NZW type IL‑10R1 and the effect on B lymphocyte function

Cheng Diao, Zanmei Qi, Shuyan Du, Xinzhe Cai, Yi Jiang
Pages: 353-358
Published online on: 15 April 2014

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Article

Increased circulating T‑helper 22 cells in patients with dilated cardiomyopathy

Qing Kong, Xiaomo Li, Weifeng Wu, Fan Yang, Yanli Liu, Wenyin Lai, Xiaofen Pan, Mengsha Gao, Yimin Xue
Pages: 359-364
Published online on: 15 April 2014

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Article

Saikosaponin‑d inhibits proliferation of DU145 human prostate cancer cells by inducing apoptosis and arresting the cell cycle at G0/G1 phase

Min Yao, Jingbo Yang, Lanqing Cao, Lian Zhang, Shanshan Qu, Hongwen Gao
Pages: 365-372
Published online on: 15 April 2014

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Article

Effect of peroxisome proliferator-activated receptor γ on the cholesterol efflux of peritoneal macrophages in inflammation

Kun He, Yue Li, Kang Yang, Jian-Ping Gong, Pei-Zhi Li
Pages: 373-378
Published online on: 29 April 2014

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Article

Prevalence and range of GJB2 and SLC26A4 mutations in patients with autosomal recessive non‑syndromic hearing loss

Hua Jiang, Jia Chen, Xin‑Ji Shan, Ying Li, Jian‑Guo He, Bei‑Bei Yang
Pages: 379-386
Published online on: 15 April 2014

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Article

Role of CIP2A in the antitumor effect of bortezomib in colon cancer

Yayun Ding, Yueguo Wang, Shaoqing Ju, Xinghua  Wu, Wencai Zhu, Feng Shi, Liping Mao
Pages: 387-392
Published online on: 24 April 2014

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Article

microRNA‑145 inhibits cell proliferation, migration and invasion by targeting matrix metallopeptidase-11 in renal cell carcinoma

Deyao Wu, Min Li, Linmao Wang, Yunfeng Zhou, Jian Zhou, Huixing Pan, Ping Qu
Pages: 393-398
Published online on: 15 April 2014

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Article

PAX6, a novel target of miR-335, inhibits cell proliferation and invasion in glioma cells Retraction in /10.3892/mmr.2021.12299

Quan Cheng, Hui Cao, Zigui Chen, Zhiming Ma, Xin Wan, Renjun Peng, Bing Jiang
Pages: 399-404
Published online on: 15 April 2014

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Article

Substituted 3‑acyl‑2‑phenylamino‑1,4‑naphthoquinones intercalate into DNA and cause genotoxicity through the increased generation of reactive oxygen species culminating in cell death

Mirelle Sifroni Farias, Claus Tröger Pich, Maicon Roberto Kviecinski, Nádia Cristina Falcão Bucker, Karina Bettega Felipe, Fabiana Ourique Da Silva, Tânia Mara Fisher Günther, João Francisco Correia, David Ríos, Julio Benites, Jaime A. Valderrama, Pedro Buc Calderon, Rozangela Curi Pedrosa
Pages: 405-410
Published online on: 16 April 2014

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Article

Temozolomide induces autophagy via ATM‑AMPK‑ULK1 pathways in glioma

Yuhui Zou, Qiong Wang, Bingling Li, Bing Xie, Weimin Wang
Pages: 411-416
Published online on: 15 April 2014

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Article

Sperm‑associated antigen 9 promotes astrocytoma cell invasion through the upregulation of podocalyxin

Jiaode Jiang, Yunsheng Liu, Wenhua Fang, Feng Liu
Pages: 417-422
Published online on: 24 April 2014

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Article

Regulation of the HMOX1 gene by the transcription factor AP-2δ with unique DNA binding site

Liyun Sun, Yuxia Zhao, Shaohua Gu, Yumin Mao, Chaoneng Ji, Xiujuan Xin
Pages: 423-428
Published online on: 28 April 2014

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Article

Therapeutic effect of Zeng Ye decoction on primary Sjögren's syndrome via upregulation of aquaporin‑1 and aquaporin‑5 expression levels

Xiaodan Wu, Changhong Ren, Hongwei Zhou, Lin Zhang, Cheng Juan, Yong Yang
Pages: 429-434
Published online on: 02 May 2014

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Association between CLOCK, PER3 and CCRN4L with non‑small cell lung cancer in Brazilian patients

Patricia Couto, Debora Miranda, Renalice Vieira, Alyne Vilhena, Luiz De Marco, Luciana Bastos‑Rodrigues
Pages: 435-440
Published online on: 08 May 2014

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Novel curcumin analogue IHCH exhibits potent anti‑proliferative effects by inducing autophagy in A549 lung cancer cells

Guang‑Zhou Zhou, Su‑Li Xu, Gang‑Chun Sun, Xiao‑Bing Chen
Pages: 441-446
Published online on: 24 April 2014

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Anti‑inflammatory effects of triptolide by inhibiting the NF‑κB signalling pathway in LPS‑induced acute lung injury in a murine model

Xian Wang, Lei Zhang, Wei Duan, Bin Liu, Ping Gong, Yusong Ding, Xiongwen Wu
Pages: 447-452
Published online on: 28 April 2014

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Inhibition of the Jagged/Notch pathway inhibits retinoblastoma cell proliferation via suppressing the PI3K/Akt, Src, p38MAPK and Wnt/β‑catenin signaling pathways

Wei Xiao, Xiaoyun Chen, Mingguang He
Pages: 453-458
Published online on: 06 May 2014

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Effects of normal aging on myelin sheath ultrastructures in the somatic sensorimotor system of rats

Fang Xie, Ping Liang, Han Fu, Jiu‑Cong Zhang, Jun Chen
Pages: 459-466
Published online on: 09 May 2014

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FOXP1 has a low expression in human gliomas and its overexpression inhibits proliferation, invasion and migration of human glioma U251 cells

Liang Xue, Shuyuan Yue, Jianning Zhang
Pages: 467-472
Published online on: 29 April 2014

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MicroRNA‑195 inhibits colorectal cancer cell proliferation, colony‑formation and invasion through targeting CARMA3

Ling Wang, Liyuan Qian, Xiaorong Li, Jin Yan
Pages: 473-478
Published online on: 24 April 2014

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Differentially‑expressed genes identified by suppression subtractive hybridization in the bone marrow hematopoietic stem cells of patients with psoriasis

Zhenying Zhang, Zhen Yu, Pan Tian, Suchun Hou, Shixin Han, Xuejing Tan, Yongjun Piao, Xiaoming Liu
Pages: 479-485
Published online on: 02 May 2014

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Article

Growth hormone protects colorectal cancer cells from radiation by improving the ability of DNA damage repair

Xiao‑Yu Wu, Che Chen, Xue‑Quan Yao, Qin‑Hong Cao, Zhe Xu, Wei‑Su Li, Fu‑Kun Liu, Gang Li
Pages: 486-490
Published online on: 24 April 2014

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Article

Ocular albinism type 1‑induced melanoma cell migration is mediated through the RAS/RAF/MEK/ERK signaling pathway

Jun Bai, Xin Xie, Yun Lei, Gaili An, Li He, Xiaopeng Lv
Pages: 491-495
Published online on: 15 April 2014

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Identification of genetic variants of lecithin cholesterol acyltransferase in individuals with high HDL‑C levels

Mohsen Naseri, Mehdi Hedayati, Maryam Sadat Daneshpour, Fatemeh Bandarian, Fereidoun Azizi
Pages: 496-502
Published online on: 24 April 2014

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Asiaticoside, a component of Centella asiatica, inhibits melanogenesis in B16F10 mouse melanoma

Ku Jung Kwon, Seunghee Bae, Karam Kim, In Sook An, Kyu Joong Ahn, Sungkwan An, Hwa Jun Cha
Pages: 503-507
Published online on: 16 April 2014

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Cartilage tissue engineering using PHBV and PHBV/Bioglass scaffolds

Mingshu Zhou, Dong Yu
Pages: 508-514
Published online on: 15 April 2014

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Article

Baicalein increases the cytotoxicity of cisplatin by enhancing gap junction intercellular communication

Yiwen Wang, Qin Wang, Suzhi Zhang, Yuan Zhang, Liang Tao
Pages: 515-521
Published online on: 16 April 2014

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Faecal calprotectin as a novel biomarker for differentiating between inflammatory bowel disease and irritable bowel syndrome

Ming‑Hui Chang, Jen‑Wei Chou, Shan‑Ming Chen, Ming‑Chang Tsai, Yu‑Shu Sun, Chun‑Che Lin, Ching‑Pin Lin
Pages: 522-526
Published online on: 24 April 2014

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miR‑376b‑5p regulates angiogenesis in cerebral ischemia

Ling‑Juan Li, Qing Huang, Ning Zhang, Gui-Bin Wang, Yun‑Hai Liu
Pages: 527-535
Published online on: 24 April 2014

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Remote ischemic postconditioning protects the heart by upregulating ALDH2 expression levels through the PI3K/Akt signaling pathway

Ying Yu, Xian‑Jie Jia, Qiao‑Feng Zong, Guan‑Jun Zhang, Hong‑Wei Ye, Jie Hu, Qin Gao, Su‑Dong Guan
Pages: 536-542
Published online on: 15 April 2014

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Phenethyl isothiocyanate inhibits growth of human chronic myeloid leukemia K562 cells via reactive oxygen species generation and caspases

Yating Wang, Sixi Wei, Jishi Wang, Qin Fang, Qixiang Chai
Pages: 543-549
Published online on: 24 April 2014

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MicroRNA-155 inhibits migration of trophoblast cells and contributes to the pathogenesis of severe preeclampsia by regulating endothelial nitric oxide synthase

Xuelan Li, Chunfang Li, Xin Dong, Wenli Gou
Pages: 550-554
Published online on: 06 May 2014

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Hepatoprotective effects of erythropoietin on D‑galactosamine/lipopolysaccharide‑induced fulminant hepatic failure in mice

Xue‑Fei Yang, Yi He, Hai‑Yuan Li, Xin Liu, Huan Chen, Jian‑Bang Liu, Wen‑Jun Ji, Bing Wang, Li‑Na Chen
Pages: 555-559
Published online on: 24 April 2014

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Article

Cardioprotective effects of phosphocreatine on myocardial cell ultrastructure and calcium-sensing receptor expression in the acute period following high level spinal cord injury

Hui Chen, Chao Gong, Cheng Ma, Xiaoni Zhang, Lishuang Xu, Caizhu Lin
Pages: 560-566
Published online on: 08 May 2014

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Preparation and characterization of luteinising‑hormone releasing hormone nanoliposomal microbubbles specifically targeting ovarian cancer cells in vitro

Jinyi Zhang, Sisun Liu, Yuanfang Zhu, Liping Zhang, Wenjuan Li, Fen Wang, Shuying Huang
Pages: 567-571
Published online on: 06 May 2014

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Journal Cover
April-2026 Volume 33 Issue 4

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Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Prostate‑specific membrane antigen: Molecular functions and emerging roles as a therapeutic target (Review)

Ryuta Watanabe, Tomohisa Sakaue, Noriyoshi Miura, Tadahiko Kikugawa, Takashi Saika
Article Number: 122
Published online on: 26 February 2026

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[Retracted] MicroRNA‑486‑5p inhibits the growth of human hypertrophic scar fibroblasts by regulating Smad2 expression

Yingying Shi, Luping Wang, Pijun Yu, Yi Liu, Wei Chen
Article Number: 121
Published online on: 25 February 2026

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Prenatal lipopolysaccharide exposure programs cardiac fibrosis via dysregulating of connexin 43 in offspring rats

Yan Wen, Yao Yuan, Haigang Zhang, Ya Liu
Article Number: 120
Published online on: 24 February 2026

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[Retracted] Upregulated microRNA‑671‑3p promotes tumor progression by suppressing forkhead box P2 expression in non‑small‑cell lung cancer

Zhi-Ying Li, Zi-Zhou Zhang, Hui Bi, Qiu-Di Zhang, Su-Juan Zhang, Lin Zhou, Xiao-Qin Zhu, Jun Zhou
Article Number: 119
Published online on: 16 February 2026

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STAT1 accelerates cutaneous melanoma progression through TUBB4A expression regulation

Rongxin Zhao, Kexin Fang, Xiaofei Zhang, Hongchao Li
Article Number: 118
Published online on: 13 February 2026

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Research progress on long non‑coding RNAs in lung cancer (Review)

Renjie Pan, Chaohui Wang, Yan Tang, Fengzhou Zhong, Yan Zhuang, Qiuxia Zhao
Article Number: 117
Published online on: 12 February 2026

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ULK1 activates NCOA4‑mediated ferritinophagy via the Beclin1/VPS34 complex in cardiomyocyte hypertrophy

Qianhui Zhang, Meitian Zhang, Yongsheng Liu, Pilong Shi, Hanping Qi, Man Jiang, Yonggang Cao, Hongli Sun
Article Number: 116
Published online on: 12 February 2026

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miRNA‑29a inhibits the proliferation of HUVECs by regulating the ITGB1/β‑catenin/c‑Myc pathway

Qi Sun, Wenting Chen, Shan Zhang, Xinni Zhong, Yafen Wu, Yingying Qian, Lei Zhu, Ting Zhang, Wei Li
Article Number: 115
Published online on: 12 February 2026

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Puerarin attenuates myocardial ischemia‑reperfusion injury by inhibiting myocardium pyroptosis via the NRF2/HO‑1 signaling pathway

Xiaoyu Zheng, Jinping Li, Tianyang Hu, Li Tan, Ding Lan, Ying Deng
Article Number: 114
Published online on: 11 February 2026

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Epigenetic crossroads in intervertebral disc degeneration: Unlocking novel therapeutic avenues (Review)

Yang Hou, Lei Liu, Yongfei Guo, Jiangang Shi
Article Number: 113
Published online on: 11 February 2026

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[Retracted] miRNA‑30a‑3p inhibits metastasis and enhances radiosensitivity in esophageal carcinoma by targeting insulin‑like growth factor 1 receptor

Yanxin Fan, Xiuhua Bian, Pudong Qian, Jing Wen, Pengwei Yan, Yanhong Luo, Jing Wu, Qian Zhang
Article Number: 112
Published online on: 09 February 2026

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Circular RNAs in intervertebral disc degeneration: Current insights into mechanisms and therapeutic potentials (Review)

Luyan Wang, Ke Yang, Houjun Zhu, Dachuan Wang, Feng Wang, Xianfa Du
Article Number: 111
Published online on: 05 February 2026

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T‑cadherin and its impact on human diseases (Review)

Yan Song, Xinyi Wang, Yunfei Bian
Article Number: 110
Published online on: 05 February 2026

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Review

CD20 monoclonal antibody‑rituximab for the treatment of diffuse alveolar hemorrhage in children (Review)

Xiaobo Zhang, Xiao Wu, Yan Li, Guangmin Nong
Article Number: 109
Published online on: 05 February 2026

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N6‑methyladenosine reader insulin‑like growth factor 2 mRNA‑binding protein 2 promotes abnormal proliferation of colonic epithelial cells in type 2 diabetes mellitus by regulating midkine

Jieyao Li, Qingsheng Xie, Jihao Xu
Article Number: 108
Published online on: 04 February 2026

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Expression of Concern Open Access

[Expression of Concern] Curcumin suppresses breast tumor angiogenesis by abrogating osteopontin‑induced VEGF expression

Goutam Chakraborty, Shalini Jain, Smita Kale, Remya Raja, Santosh Kumar, Rosalin Mishra, Gopal C. Kundu
Article Number: 107
Published online on: 04 February 2026

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Research status and molecular mechanisms of disulfidptosis in cardiovascular diseases (Review)

Xiao Jin, Zelin Cheng, Xinyue Ding, Zongjun Liu
Article Number: 106
Published online on: 03 February 2026

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Role and mechanism of tetrahedral DNA nanostructures in the repair of urethral injury in rats

Caifen Guo, Jian Li
Article Number: 105
Published online on: 02 February 2026

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Retraction Open Access

[Retracted] MicroRNA‑4500 suppresses tumor progression in non‑small cell lung cancer by regulating STAT3

Zhi-Ying Li, Zi-Zhou Zhang, Hui Bi, Qiu-Di Zhang, Su-Juan Zhang, Lin Zhou, Xiao-Qin Zhu, Jun Zhou
Article Number: 104
Published online on: 02 February 2026

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Integrative bioinformatics and experimental analysis reveals FRA1 as a key mediator of tubulointerstitial inflammation in lupus nephritis

Wenpeng Ni, Jialin He, Zhouyu Zeng, Jialong Ke, Runpei Lin, Jianming Peng, Kunyi Deng, Lijuan Wen, Yanhui Chen, Chilun Zhang, Yanfen Li, Guanghong Gu
Article Number: 103
Published online on: 28 January 2026

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Correction Open Access

[Corrigendum] Resveratrol improves neurological outcome and neuroinflammation following spinal cord injury through enhancing autophagy involving the AMPK/mTOR pathway

Hong-Yu Meng, De-Cheng Shao, Han Li, Xiao-Dan Huang, Guang Yang, Bing Xu, Hai-Yun Niu
Article Number: 102
Published online on: 28 January 2026

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May-2026 Volume 33 Issue 5

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Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

Tonsil‑derived mesenchymal stem cell‑derived extracellular vesicles suppress MAPK‑NF‑κB signaling and restore osteogenic differentiation in LPS‑stimulated periodontal ligament fibroblasts

Won-Jung Bae, Su Kang Kim, Han-Soo Kim, Sang Wook Kang, Ju Yeon Ban
Article Number: 150
Published online on: 26 March 2026

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Succinylation modification in diabetes and diabetic complications: Mechanisms and functions (Review)

Yeteng Xiong, Fei Luo, Bingnan Li, Qinfeng Yang
Article Number: 149
Published online on: 26 March 2026

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Polyphyllin II regulates ROS levels and promotes ferroptosis in bladder cancer cells

Quanlai Qiao, Ruifang Guo, Zhonghua Sun, Yaxin Shi, Yuning Xie, Zhiyong Liu
Article Number: 148
Published online on: 26 March 2026

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Veronicastrum sibiricum (L.) Pennell extract alleviates inflammation‑induced muscle atrophy through NLRP3 inflammasome regulation and mitochondrial function restoration

Eunhye Lee, Minjeong Kwon, Ju-Ock Nam
Article Number: 147
Published online on: 26 March 2026

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Role and clinical importance of lactylation in tumors (Review)

Chaowei Zhang, Xinyu Tang, Yuxuan Han, Weiyi Yao, Qing Hong, Yanan Zhu, Na Chen
Article Number: 146
Published online on: 26 March 2026

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Photodynamic therapy: A paradigm shift in overcoming drug‑resistant tuberculosis (Review)

Shuhao Cheng, Yuqing Wang, Jie Yao, Guodong Cheng, Gengzhi Ye, Fapeng Shi, Xiaolei Ma
Article Number: 145
Published online on: 26 March 2026

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Heterogeneous nuclear ribonucleoprotein K in cancer biology and its therapeutic applications (Review)

Yiyu Qin, Yang Zhou
Article Number: 144
Published online on: 26 March 2026

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[Retracted] Na+/K+‑ATPase DR region‑specific antibody protects U251 cells against hypoxia reperfusion‑induced injury via the PI3K/AKT and ERK pathways

Huilin Gong, Pengbiao Lü, Jiangwei Zhang, Dandong Li, Jin Zheng, Jinning Song
Article Number: 143
Published online on: 23 March 2026

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Multi‑omics and their integration in psoriasis research (Review)

Hengyan Zhang, Danping Li, Lijuan Zhu, Heguo Yan, Licong Yang, Xuesong Yang, Ye Zhou
Article Number: 142
Published online on: 23 March 2026

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LDHA protects vascular endothelial cells from oxidative stress‑induced mitochondrial damage via HIF‑1α activation and glycolytic reprogramming

Beibei Dai, Lili Yang, Yu Zhang, Aiyong Yu
Article Number: 141
Published online on: 23 March 2026

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Mechanism of BRCC36 affecting cardiac rupture after acute infarction through the Wnt‑JNK signaling pathway

Yongzhe Guo, Linyan Chen, Shumei Li, Xintao Zhang, Huizhong Lin
Article Number: 140
Published online on: 20 March 2026

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Correction Open Access

[Corrigendum] Puerarin alleviates the ototoxicity of gentamicin by inhibiting the mitochondria‑dependent apoptosis pathway

Ping Niu, Yuxuan Sun, Shiyi Wang, Guang Li, Xiaomin Tang, Jiaqiang Sun, Chunchen Pan, Jingwu Sun
Article Number: 139
Published online on: 19 March 2026

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Role of liver X receptors in the pathogenesis and treatment of chronic liver disease (Review)

Honghui You, Xiangjun Tang, Xiaoyan Fu, Jiaqi Zhou, Liyuan Wang, Hongxia Zhang, Xianhong Du, Shujuan Liang, Meifang Liu
Article Number: 138
Published online on: 19 March 2026

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Mechanistic insights and therapeutic potential of sphingosine‑1‑phosphate in the development of pulmonary fibrosis (Review)

Yanling Qin, Chenqi Tang, Sen Tan, Guangnan Liu
Article Number: 137
Published online on: 18 March 2026

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Advances in the biological functions of miR‑205 in various diseases (Review)

Dandan Chai, Hua Du, Yingxu Shi
Article Number: 136
Published online on: 18 March 2026

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[Retracted] MicroRNA‑25‑3p regulates human nucleus pulposus cell proliferation and apoptosis in intervertebral disc degeneration by targeting Bim

Zhifang Zhao, Jie Zheng, Youchen Ye, Kefeng Zhao, Ruozhang Wang, Ran Wang
Article Number: 135
Published online on: 16 March 2026

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Precision medicine approach to coronary artery disease: Haptoglobin phenotype‑guided risk assessment

Zhengxin He, Hong Liu, Keran Jia, Daxin Lei, Liyun An, Jia Wang, Fukun Wang
Article Number: 134
Published online on: 12 March 2026

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Expression of Concern Open Access

[Expression of Concern] Dexmedetomidine protects against sepsis‑associated encephalopathy through Hsp90/AKT signaling

Lijun Yin, Xuejun Chen, Hongbo Ji, Shunli Gao
Article Number: 133
Published online on: 11 March 2026

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Glucose‑driven TRIB3 enhances the tumorigenic potential of colon cancer via the PI3K/AKT pathway

Yunting Bai, Xuying Huang, Guangyu An, Yang Ge, Rui Yan, Dan Yu
Article Number: 132
Published online on: 10 March 2026

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Retraction Open Access

[Retracted] miR‑222 regulates brain injury and inflammation following intracerebral hemorrhage by targeting ITGB8

Yan-Yan Bai, Jun-Zhi Niu
Article Number: 131
Published online on: 09 March 2026

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Dexmedetomidine protects against myocardial ischemia reperfusion injury by inhibiting the TLR2‑NF‑κB pathway in diabetic mice

Zhengjie Chen, Liangyu Zheng, Gang Chen
Article Number: 130
Published online on: 06 March 2026

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Long non‑coding RNA NKILA regulates the JAK2/STAT3 pathway to exacerbate TGF‑β1‑mediated renal fibrosis

Yu Han, Siqi Yang, Jing Zhang, Yaoguang Wang, Xi Zhao, Huan Liu
Article Number: 129
Published online on: 05 March 2026

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Retraction Open Access

[Retracted] Combination of HSP90 and autophagy inhibitors promotes hepatocellular carcinoma apoptosis following incomplete thermal ablation

Fen Chen, Haiyang Xie, Haiwei Bao, Laurencia Violetta, Shusen Zheng
Article Number: 128
Published online on: 05 March 2026

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Advances regarding physiological functions and mechanisms of theaflavin‑3,3'‑digallate (Review)

Teng Ma, Siwei Zhang, Miaomiao Xiao, Zhijian Ma, Junhong Guan
Article Number: 127
Published online on: 04 March 2026

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Mechanisms and therapeutic potential of glycyrrhizic acid: Insights into key signaling pathways and disease modulation (Review)

Jinjin Yu, Huiheng Qu, Weicheng Xu, Yiming Fang, Nan Wang, Wei Shi
Article Number: 126
Published online on: 04 March 2026

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Pyroptosis in cerebral ischemia‑reperfusion injury: Molecular mechanisms and therapeutic implications (Review)

Ze Li, Qiuli Ming, Tianyu Yang, Mengna Liu, Linpeng Fu, Jingshuang Yang, Zhaofeng Lu
Article Number: 125
Published online on: 04 March 2026

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Characteristics of chromosomal instability‑related lncRNAs associated with progression and prognosis in breast cancer

Qi Chen, Hui Chen, Hui Yang, Yin Tao, Xiaolan Zhu
Article Number: 124
Published online on: 04 March 2026

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Correction Open Access

[Corrigendum] Associations between Huwe1 and autophagy in rat cerebral neuron oxygen‑glucose deprivation and reperfusion injury 

Guo-Qian He, Yan Chen, Hui-Juan Liao, Wen-Ming Xu, Wei Zhang, Guo-Lin He
Article Number: 123
Published online on: 26 February 2026

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