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Molecular Medicine Reports
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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
July-2014 Volume 10 Issue 1

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

DNA methylation profiles in ovarian cancer: Implication in diagnosis and therapy (Review)

Ourania Koukoura, Demetrios A. Spandidos, Alexandros Daponte, Stavros Sifakis
Pages: 3-9
Published online on: 08 May 2014

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Article Open Access

Monoglucosyl‑rutin as a potential radioprotector in mammalian cells

Shigeaki Sunada, Hiroshi Fujisawa, Ian M. Cartwright, Junko Maeda, Colleen A. Brents, Kazue Mizuno, Yasushi Aizawa, Takamitsu A. Kato, Mitsuru Uesaka
Pages: 10-14
Published online on: 24 April 2014

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Article Open Access

Atoh1 expression levels define the fate of rat cochlear nonsensory epithelial cells in vitro

Wen‑Wei Luo, Juan‑Mei Yang, Zhao Han, Ya‑Sheng Yuan, Hai‑Bin Sheng, Xiang Liu, Fang‑Lu Chi
Pages: 15-20
Published online on: 30 April 2014

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Article Open Access

Induction of E-cadherin+ human amniotic fluid cell differentiation into oocyte-like cells via culture in medium supplemented with follicular fluid

Te Liu, Yongyi Huang, Yanzhen Bu, Yanhui Zhao, Gang Zou, Zhixue Liu
Pages: 21-28
Published online on: 29 April 2014

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Article Open Access

Tetramethylpyrazine promotes the proliferation and migration of brain endothelial cells

Mingshun Zhang, Feng Gao, Fengmeng Teng, Chunbing Zhang
Pages: 29-32
Published online on: 24 April 2014

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Article Open Access

Colorectal polyp model established by transplacental BMP4 RNAi

Xin Jin, Zhongmei Chen, Li Xiang, Qing Luo, Zhenghua Guo, Xionghui Ding, Xianqing Jin
Pages: 33-38
Published online on: 07 May 2014

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Article Open Access

Epithelial‑mesenchymal transition and apoptosis of renal tubular epithelial cells are associated with disease progression in patients with IgA nephropathy

Junxia Yao, Zunji Ke, Xiaoyan Wang, Feng Peng, Bin Li, Renliang Wu
Pages: 39-44
Published online on: 24 April 2014

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Article Open Access

Complement anaphylatoxin C4a inhibits C5a-induced neointima formation following arterial injury

Yan Zhao, Heng Xu, Wenhui Yu, Bao-Dong Xie
Pages: 45-52
Published online on: 24 April 2014

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Article Open Access

Role and mechanism of Twist1 in modulating the chemosensitivity of FaDu cells

Sumei Lu, Liang Yu, Yakui Mu, Juke Ma, Jiajun Tian, Wei Xu, Haibo Wang
Pages: 53-60
Published online on: 06 May 2014

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Article Open Access

Hyperoxia arrests pulmonary development in newborn rats via disruption of endothelial tight junctions and downregulation of Cx40

Chong Li, Jianhua Fu, Hongyu Liu, Haiping Yang, Li Yao, Kai You, Xindong Xue
Pages: 61-67
Published online on: 28 April 2014

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Article Open Access

Multiple-locus variable number of tandem repeats analysis of Salmonella enterica serotype paratyphi A from Yuxi and comparison with isolates from the Chinese Medical Culture Collection Center

Yingbo Yao, Xiaoyan Cui, Qingshan Chen, Xinrong Huang, Bradley Elmore, Qing Pan, Shukun Wang, Jie Liu
Pages: 68-74
Published online on: 24 April 2014

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Article Open Access

An interspecies conserved motif of the mouse immune system-released activating agent (ISRAA) induces proliferative effects on human cells

Safa Taha, Mohamed Dahmani Fathallah, Moiz Bakhiet
Pages: 75-81
Published online on: 08 May 2014

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Article Open Access

KNDC1 knockdown protects human umbilical vein endothelial cells from senescence

Chunyan Zhang, Yong-Zhan Zhen, Ya-Jun Lin, Jiang Liu, Jie Wei, Rong Xu, Gang Hu
Pages: 82-88
Published online on: 30 April 2014

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Article

Cucurbitacin B inhibits growth and induces apoptosis through the JAK2/STAT3 and MAPK pathways in SH‑SY5Y human neuroblastoma cells

Qian Zheng, Yunyi Liu, Weiwei Liu, Fengyun Ma, Yi Zhou, Mingjie Chen, Junli Chang, Yuesheng Wang, Guangxiao Yang, Guangyuan He
Pages: 89-94
Published online on: 24 April 2014

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Article

Application of two-dimensional electrophoresis and mass spectrometry to screen endometriosis‑related proteins

Hanikezi Tuerxun, Yanmei Zhang, Fei Ji, Aixingzi Aili, Xinhua Yang, Yan Ding
Pages: 95-100
Published online on: 15 April 2014

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Article

Protective effect of resveratrol against acute lung injury induced by lipopolysaccharide via inhibiting the myd88‑dependent Toll-like receptor 4 signaling pathway

Zhuo Zhang, Ni Chen, Jin‑Bo Liu, Jian‑Bo Wu, Jing Zhang, Ying Zhang, Xian Jiang
Pages: 101-106
Published online on: 09 May 2014

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Article

Involvement of Rac in thromboxane A2‑induced human platelet activation: Regulation of sCD40 ligand release and PDGF‑AB secretion

Yasunari Kageyama, Tomoaki Doi, Rie Matsushima‑Nishiwaki, Yuko Iida, Shigeru Akamatsu, Akira Kondo, Gen Kuroyanagi, Naohiro Yamamoto, Jun Mizutani, Takanobu Otsuka, Haruhiko Tokuda, Hiroki Iida, Osamu Kozawa, Shinji Ogura
Pages: 107-112
Published online on: 15 April 2014

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Article

Co‑expression network analysis of differentially expressed genes associated with metastasis in prolactin pituitary tumors

Wei Zhang, Zhenle Zang, Yechun Song, Hui Yang, Qing Yin
Pages: 113-118
Published online on: 15 April 2014

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Article

Analysis of differentially expressed genes between rheumatoid arthritis and osteoarthritis based on the gene co‑expression network

Qing‑You Lu, Qing‑Hui Han, Xia Li, Zeng‑Chun Li, Yu‑Tao Pan, Lin Liu, Qing‑Ge Fu
Pages: 119-124
Published online on: 24 April 2014

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Article

Suppressive effect of microRNA-126 on oral squamous cell carcinoma in vitro

Xiaolun Yang, Hanjiang Wu, Tianyou Ling
Pages: 125-130
Published online on: 24 April 2014

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Article

Prognostic significance of nemo‑like kinase in nasopharyngeal carcinoma

Size Chen, Zhijian Ma, Xuemei Chen, Jiren Zhang
Pages: 131-136
Published online on: 28 April 2014

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Article

Small interfering RNA targeting ILK inhibits EMT in human peritoneal mesothelial cells through phosphorylation of GSK‑3β

Lingrong Luo, Hong Liu, Zheng Dong, Lin Sun, Youming Peng, Fuyou Liu
Pages: 137-144
Published online on: 17 April 2014

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Article

Identification of microRNAs involved in growth arrest and cell death in hydrogen peroxide-treated human dermal papilla cells

Ok-Yeon Kim, Hwa Jun Cha, Kyu Joong Ahn, In-Sook An, Sungkwan An, Seunghee Bae
Pages: 145-154
Published online on: 16 April 2014

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Article

microRNA‑145 inhibits osteosarcoma cell proliferation and invasion by targeting ROCK1 Retraction in /10.3892/mmr.2022.12790

Pengfei Lei, Jie Xie, Long Wang, Xucheng Yang, Zixun Dai, Yihe Hu
Pages: 155-160
Published online on: 28 April 2014

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Article

MicroRNA‑21 regulation of the progression of viral myocarditis to dilated cardiomyopathy

Hong‑Fei Xu, Yu‑Jie Ding, Zhi‑Xiang Zhang, Zu‑Feng Wang, Cheng‑Liang Luo, Bei‑Xu Li, Yi‑Wen Shen, Lu‑Yang Tao, Zi‑Qin Zhao
Pages: 161-168
Published online on: 02 May 2014

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Article

Knockdown of IRX2 inhibits osteosarcoma cell proliferation and invasion by the AKT/MMP9 signaling pathway

Tielong Liu, Weiwei Zhou, Fei Zhang, Guodong Shi, Honglin Teng, Jianru Xiao, Yan Wang
Pages: 169-174
Published online on: 07 May 2014

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Article

Clinical and pathological features of patients with nemaline myopathy

Xi Yin, Chuan Qiang Pu, Qian Wang, Jie Xiao Liu, Yan Ling Mao
Pages: 175-182
Published online on: 24 April 2014

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Article

Tumoricidal activity of combining the agonistic DR5 antibody D-6 with cisplatin in C30 cisplatin‑resistant ovarian cancer in vitro and in vivo

Yan Huang, Baoquan Liang, Qin Jiang, Chen Chen, Kun Yang, Chunmei Li, Ai Zheng
Pages: 183-190
Published online on: 28 April 2014

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Article

Prognostic value of PPM1D in 800 gastric cancer patients

Dan Ma, Chao-Jun Zhang, Zu-Lin Chen, Hua Yang
Pages: 191-194
Published online on: 24 April 2014

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Article

Impact of estrogen-related receptor α on the biological characteristics of rat mandibular condylar chondrocytes

Xin Chen, Chuan Cai, Jing Liu, Li Wen, Xi Wang, Yin Ding
Pages: 195-202
Published online on: 02 May 2014

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Article

Activation of STAT5 contributes to proliferation in U87 human glioblastoma multiforme cells

Cui Feng, Shouqiang Cao
Pages: 203-210
Published online on: 08 May 2014

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Article

Sanguinarine protects against pressure overload‑induced cardiac remodeling via inhibition of nuclear factor-κB activation

Wei Deng, Yi Fang, Yuan Liu, Heng Zhou, Zhihong Cheng, Yang Zhang, Di Sun, Mengying He, Yafen Lin, Rui Zhang, Jieyu Zhang, Wei Li, Qizhu Tang
Pages: 211-216
Published online on: 02 May 2014

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Article

Gene profiling in the dynamic regulation of the lifespan of the myelin sheath structure in the optic nerve of rats

Fang Xie, Han Fu, Jiu‑Cong Zhang, Xue‑Feng Chen, Xiao‑Liang Wang, Jun Chen
Pages: 217-222
Published online on: 09 May 2014

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Article

Expression of microRNA-26b, an obesity-related microRNA, is regulated by free fatty acids, glucose, dexamethasone and growth hormone in human adipocytes

Guangfeng Xu, Chunmei Shi, Chenbo Ji, Guixian Song, Ling Chen, Lei Yang, Yaping Zhao, Xirong Guo
Pages: 223-228
Published online on: 02 May 2014

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Article

Identification of the typical miRNAs and target genes in hepatocellular carcinoma

Keqiang Han, Jing Li, Hongzhi Zhao, Ping Liang, Xiaobing Huang, Lu Zheng, Yuming Li, Tonghan Yang, Liang Wang
Pages: 229-235
Published online on: 28 April 2014

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Article

Th17 cells are associated with the Th1/Th2‑cell balance during Echinococcus multilocularis infection

Xiumin Ma, Liang Wang, Hui Zhao, Nannan Pang, Fengbo Zhang, Tao Jiang, Xuelei Liu, Wulamu Mamuti, Hao Wen, Jianbing Ding
Pages: 236-240
Published online on: 24 April 2014

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Article

RNA‑seq analysis of synovial fibroblasts in human rheumatoid arthritis

Xiuhui Wang, Shengli Xia, Beigang Fu
Pages: 241-247
Published online on: 24 April 2014

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Article

Effect of Gua Lou Gui Zhi decoction on focal cerebral ischemia‑reperfusion injury through regulating the expression of excitatory amino acids and their receptors

Xianwen Chen, Huang Li, Mingqing Huang, Mei Huang, Wei Xu, Kedan Chu, Lidian Chen, Yuqin Zhang
Pages: 248-254
Published online on: 28 April 2014

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Article

Localization and expression patterns of prolactin‑like protein J in mouse testis

Qiaozhen Yang, Jie Hao, Miao He, Maoxin Chen, Gang Li
Pages: 255-261
Published online on: 07 May 2014

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Article

Lycopene inhibits neointimal hyperplasia through regulating lipid metabolism and suppressing oxidative stress

Min Mao, Han Lei, Qing Liu, Rui He, Zhong Zuo, Nan Zhang, Chao Zhou
Pages: 262-268
Published online on: 24 April 2014

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Article

Theophylline improves lipopolysaccharide-induced alveolarization arrest through inflammatory regulation

Hua He, Fei Chen, Wensi Ni, Jianhui Li, Yongjun Zhang
Pages: 269-275
Published online on: 24 April 2014

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Article

Peroxisome proliferator-activated receptor γ ligands inhibit VEGF-mediated vasculogenic mimicry of prostate cancer through the AKT signaling pathway

Liang Qin, Ye Ren, An-Min Chen, Feng-Jing Guo, Fei Xu, Chen Gong, Peng Cheng, Yu Du, Hui Liao
Pages: 276-282
Published online on: 29 April 2014

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Article

miR‑20a is an independent prognostic factor in colorectal cancer and is involved in cell metastasis

Guang‑Jun Zhang, Yu Li, He Zhou, Hua‑Xu Xiao, Tong Zhou
Pages: 283-291
Published online on: 15 April 2014

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Article

microRNAs mediate oleic acid-induced acute lung injury in rats using an alternative injury mechanism

Sang Mook Lee, Hyunsoo Choi, Geumjin Yang, Ki Cheol Park, Sikyoung Jeong, Sungyoup Hong
Pages: 292-300
Published online on: 15 April 2014

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Article

Pingyangmycin stimulates apoptosis in human hemangioma‑derived endothelial cells through activation of the p53 pathway

Jun‑Bo Tu, Quan‑Yan Li, Fei Jiang, Xiao‑Yi Hu, Rui‑Zhao Ma, Qiang Dong, Hao Zhang, Parukjan Pattar, Shi‑Xian Li
Pages: 301-305
Published online on: 24 April 2014

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Article

Anti-fibrotic effects of specific-siRNA targeting of the receptor for advanced glycation end products in a rat model of experimental hepatic fibrosis

Xiao-Gang Cai, Jin-Rong Xia, Wei-Dong Li, Feng-Lin Lu, Juan Liu, Qin Lu, Hong Zhi
Pages: 306-314
Published online on: 02 May 2014

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Article

microRNA-200c downregulates XIAP expression to suppress proliferation and promote apoptosis of triple-negative breast cancer cells

Yi Ren, Xuedong Han, Kun Yu, Su'an Sun, Linlin Zhen, Zhi Li, Shui Wang
Pages: 315-321
Published online on: 08 May 2014

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Article

Fms-related tyrosine kinase 3 ligand promotes proliferation of placenta amnion and chorion mesenchymal stem cells in vitro

Fang Li, Yunyun Xu, Xiaoxia Xu, Biao Xu, Juan Zhao, Xueguang Zhang
Pages: 322-328
Published online on: 08 May 2014

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Article

Generation of liver-specific TGF-α and c-Myc-overexpressing fibroblasts for future creation of a liver cancer porcine model

Jeeyoung Kim, Huijeong Ahn, Heung-Myong Woo, Eunsong Lee, Geun-Shik Lee
Pages: 329-335
Published online on: 07 May 2014

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Article

AP‑4 predicts poor prognosis in non‑small cell lung cancer

Hai Gong, Shaorong Han, Hui Yao, Hui Zhao, Yanming Wang
Pages: 336-340
Published online on: 02 May 2014

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Article

Inhibition of invasion and epithelial-mesenchymal transition of human breast cancer cells by hydrogen sulfide through decreased phospho-p38 expression

Min Lv, Yan Li, Ming-Hua Ji, Ming Zhuang, Jin-Hai Tang
Pages: 341-346
Published online on: 17 April 2014

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Article

Therapeutic effects of sorafenib on the A549/DDP human lung adenocarcinoma cell line in vitro

Xiang‑Qi Chen, Yu‑Lan Wang, Zhi‑Ying Li, Ting‑Yan Lin
Pages: 347-352
Published online on: 24 April 2014

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Article

Signal transduction mechanism of the NZW type IL‑10R1 and the effect on B lymphocyte function

Cheng Diao, Zanmei Qi, Shuyan Du, Xinzhe Cai, Yi Jiang
Pages: 353-358
Published online on: 15 April 2014

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Article

Increased circulating T‑helper 22 cells in patients with dilated cardiomyopathy

Qing Kong, Xiaomo Li, Weifeng Wu, Fan Yang, Yanli Liu, Wenyin Lai, Xiaofen Pan, Mengsha Gao, Yimin Xue
Pages: 359-364
Published online on: 15 April 2014

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Article

Saikosaponin‑d inhibits proliferation of DU145 human prostate cancer cells by inducing apoptosis and arresting the cell cycle at G0/G1 phase

Min Yao, Jingbo Yang, Lanqing Cao, Lian Zhang, Shanshan Qu, Hongwen Gao
Pages: 365-372
Published online on: 15 April 2014

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Article

Effect of peroxisome proliferator-activated receptor γ on the cholesterol efflux of peritoneal macrophages in inflammation

Kun He, Yue Li, Kang Yang, Jian-Ping Gong, Pei-Zhi Li
Pages: 373-378
Published online on: 29 April 2014

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Article

Prevalence and range of GJB2 and SLC26A4 mutations in patients with autosomal recessive non‑syndromic hearing loss

Hua Jiang, Jia Chen, Xin‑Ji Shan, Ying Li, Jian‑Guo He, Bei‑Bei Yang
Pages: 379-386
Published online on: 15 April 2014

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Article

Role of CIP2A in the antitumor effect of bortezomib in colon cancer

Yayun Ding, Yueguo Wang, Shaoqing Ju, Xinghua  Wu, Wencai Zhu, Feng Shi, Liping Mao
Pages: 387-392
Published online on: 24 April 2014

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Article

microRNA‑145 inhibits cell proliferation, migration and invasion by targeting matrix metallopeptidase-11 in renal cell carcinoma

Deyao Wu, Min Li, Linmao Wang, Yunfeng Zhou, Jian Zhou, Huixing Pan, Ping Qu
Pages: 393-398
Published online on: 15 April 2014

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Article

PAX6, a novel target of miR-335, inhibits cell proliferation and invasion in glioma cells Retraction in /10.3892/mmr.2021.12299

Quan Cheng, Hui Cao, Zigui Chen, Zhiming Ma, Xin Wan, Renjun Peng, Bing Jiang
Pages: 399-404
Published online on: 15 April 2014

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Article

Substituted 3‑acyl‑2‑phenylamino‑1,4‑naphthoquinones intercalate into DNA and cause genotoxicity through the increased generation of reactive oxygen species culminating in cell death

Mirelle Sifroni Farias, Claus Tröger Pich, Maicon Roberto Kviecinski, Nádia Cristina Falcão Bucker, Karina Bettega Felipe, Fabiana Ourique Da Silva, Tânia Mara Fisher Günther, João Francisco Correia, David Ríos, Julio Benites, Jaime A. Valderrama, Pedro Buc Calderon, Rozangela Curi Pedrosa
Pages: 405-410
Published online on: 16 April 2014

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Article

Temozolomide induces autophagy via ATM‑AMPK‑ULK1 pathways in glioma

Yuhui Zou, Qiong Wang, Bingling Li, Bing Xie, Weimin Wang
Pages: 411-416
Published online on: 15 April 2014

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Article

Sperm‑associated antigen 9 promotes astrocytoma cell invasion through the upregulation of podocalyxin

Jiaode Jiang, Yunsheng Liu, Wenhua Fang, Feng Liu
Pages: 417-422
Published online on: 24 April 2014

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Article

Regulation of the HMOX1 gene by the transcription factor AP-2δ with unique DNA binding site

Liyun Sun, Yuxia Zhao, Shaohua Gu, Yumin Mao, Chaoneng Ji, Xiujuan Xin
Pages: 423-428
Published online on: 28 April 2014

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Article

Therapeutic effect of Zeng Ye decoction on primary Sjögren's syndrome via upregulation of aquaporin‑1 and aquaporin‑5 expression levels

Xiaodan Wu, Changhong Ren, Hongwei Zhou, Lin Zhang, Cheng Juan, Yong Yang
Pages: 429-434
Published online on: 02 May 2014

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Association between CLOCK, PER3 and CCRN4L with non‑small cell lung cancer in Brazilian patients

Patricia Couto, Debora Miranda, Renalice Vieira, Alyne Vilhena, Luiz De Marco, Luciana Bastos‑Rodrigues
Pages: 435-440
Published online on: 08 May 2014

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Novel curcumin analogue IHCH exhibits potent anti‑proliferative effects by inducing autophagy in A549 lung cancer cells

Guang‑Zhou Zhou, Su‑Li Xu, Gang‑Chun Sun, Xiao‑Bing Chen
Pages: 441-446
Published online on: 24 April 2014

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Article

Anti‑inflammatory effects of triptolide by inhibiting the NF‑κB signalling pathway in LPS‑induced acute lung injury in a murine model

Xian Wang, Lei Zhang, Wei Duan, Bin Liu, Ping Gong, Yusong Ding, Xiongwen Wu
Pages: 447-452
Published online on: 28 April 2014

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Inhibition of the Jagged/Notch pathway inhibits retinoblastoma cell proliferation via suppressing the PI3K/Akt, Src, p38MAPK and Wnt/β‑catenin signaling pathways

Wei Xiao, Xiaoyun Chen, Mingguang He
Pages: 453-458
Published online on: 06 May 2014

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Article

Effects of normal aging on myelin sheath ultrastructures in the somatic sensorimotor system of rats

Fang Xie, Ping Liang, Han Fu, Jiu‑Cong Zhang, Jun Chen
Pages: 459-466
Published online on: 09 May 2014

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Article

FOXP1 has a low expression in human gliomas and its overexpression inhibits proliferation, invasion and migration of human glioma U251 cells

Liang Xue, Shuyuan Yue, Jianning Zhang
Pages: 467-472
Published online on: 29 April 2014

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Article

MicroRNA‑195 inhibits colorectal cancer cell proliferation, colony‑formation and invasion through targeting CARMA3

Ling Wang, Liyuan Qian, Xiaorong Li, Jin Yan
Pages: 473-478
Published online on: 24 April 2014

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Article

Differentially‑expressed genes identified by suppression subtractive hybridization in the bone marrow hematopoietic stem cells of patients with psoriasis

Zhenying Zhang, Zhen Yu, Pan Tian, Suchun Hou, Shixin Han, Xuejing Tan, Yongjun Piao, Xiaoming Liu
Pages: 479-485
Published online on: 02 May 2014

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Article

Growth hormone protects colorectal cancer cells from radiation by improving the ability of DNA damage repair

Xiao‑Yu Wu, Che Chen, Xue‑Quan Yao, Qin‑Hong Cao, Zhe Xu, Wei‑Su Li, Fu‑Kun Liu, Gang Li
Pages: 486-490
Published online on: 24 April 2014

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Article

Ocular albinism type 1‑induced melanoma cell migration is mediated through the RAS/RAF/MEK/ERK signaling pathway

Jun Bai, Xin Xie, Yun Lei, Gaili An, Li He, Xiaopeng Lv
Pages: 491-495
Published online on: 15 April 2014

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Article

Identification of genetic variants of lecithin cholesterol acyltransferase in individuals with high HDL‑C levels

Mohsen Naseri, Mehdi Hedayati, Maryam Sadat Daneshpour, Fatemeh Bandarian, Fereidoun Azizi
Pages: 496-502
Published online on: 24 April 2014

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Article

Asiaticoside, a component of Centella asiatica, inhibits melanogenesis in B16F10 mouse melanoma

Ku Jung Kwon, Seunghee Bae, Karam Kim, In Sook An, Kyu Joong Ahn, Sungkwan An, Hwa Jun Cha
Pages: 503-507
Published online on: 16 April 2014

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Article

Cartilage tissue engineering using PHBV and PHBV/Bioglass scaffolds

Mingshu Zhou, Dong Yu
Pages: 508-514
Published online on: 15 April 2014

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Article

Baicalein increases the cytotoxicity of cisplatin by enhancing gap junction intercellular communication

Yiwen Wang, Qin Wang, Suzhi Zhang, Yuan Zhang, Liang Tao
Pages: 515-521
Published online on: 16 April 2014

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Article

Faecal calprotectin as a novel biomarker for differentiating between inflammatory bowel disease and irritable bowel syndrome

Ming‑Hui Chang, Jen‑Wei Chou, Shan‑Ming Chen, Ming‑Chang Tsai, Yu‑Shu Sun, Chun‑Che Lin, Ching‑Pin Lin
Pages: 522-526
Published online on: 24 April 2014

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Article

miR‑376b‑5p regulates angiogenesis in cerebral ischemia

Ling‑Juan Li, Qing Huang, Ning Zhang, Gui-Bin Wang, Yun‑Hai Liu
Pages: 527-535
Published online on: 24 April 2014

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Article

Remote ischemic postconditioning protects the heart by upregulating ALDH2 expression levels through the PI3K/Akt signaling pathway

Ying Yu, Xian‑Jie Jia, Qiao‑Feng Zong, Guan‑Jun Zhang, Hong‑Wei Ye, Jie Hu, Qin Gao, Su‑Dong Guan
Pages: 536-542
Published online on: 15 April 2014

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Article

Phenethyl isothiocyanate inhibits growth of human chronic myeloid leukemia K562 cells via reactive oxygen species generation and caspases

Yating Wang, Sixi Wei, Jishi Wang, Qin Fang, Qixiang Chai
Pages: 543-549
Published online on: 24 April 2014

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MicroRNA-155 inhibits migration of trophoblast cells and contributes to the pathogenesis of severe preeclampsia by regulating endothelial nitric oxide synthase

Xuelan Li, Chunfang Li, Xin Dong, Wenli Gou
Pages: 550-554
Published online on: 06 May 2014

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Article

Hepatoprotective effects of erythropoietin on D‑galactosamine/lipopolysaccharide‑induced fulminant hepatic failure in mice

Xue‑Fei Yang, Yi He, Hai‑Yuan Li, Xin Liu, Huan Chen, Jian‑Bang Liu, Wen‑Jun Ji, Bing Wang, Li‑Na Chen
Pages: 555-559
Published online on: 24 April 2014

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Article

Cardioprotective effects of phosphocreatine on myocardial cell ultrastructure and calcium-sensing receptor expression in the acute period following high level spinal cord injury

Hui Chen, Chao Gong, Cheng Ma, Xiaoni Zhang, Lishuang Xu, Caizhu Lin
Pages: 560-566
Published online on: 08 May 2014

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Article

Preparation and characterization of luteinising‑hormone releasing hormone nanoliposomal microbubbles specifically targeting ovarian cancer cells in vitro

Jinyi Zhang, Sisun Liu, Yuanfang Zhu, Liping Zhang, Wenjuan Li, Fen Wang, Shuying Huang
Pages: 567-571
Published online on: 06 May 2014

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Journal Cover
February-2026 Volume 33 Issue 2

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

ISX promotes tumor migration and invasion in lung cancer by upregulating COL1A1 in vitro

Yihe Ma, Ye Chen, Yuhui Liang, Yun Huang, Miao Gong, Lifeng Tian, Xiaojun Xiao, Jingyan Liu, Qinmiao Huang
Article Number: 77
Published online on: 31 December 2025

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Role and mechanism of miR‑222‑5p in endothelial cell apoptosis

Shimeng Wang, Boxin Zhao, Ying Cui, Lin Gui, Jingyao Fan, Lijuan Huang
Article Number: 76
Published online on: 31 December 2025

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Expression of Concern Open Access

[Expression of Concern] MicroRNA-29c inhibits proliferation and promotes apoptosis in non-small cell lung cancer cells by targeting VEGFA

Shijuan Zhan, Chunfeng Wang, Fangqing Yin
Article Number: 75
Published online on: 22 December 2025

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Melatonin induces autophagy in neuroblastoma by alleviating Pak2‑mediated endoplasmic reticulum stress

Qian-Qi Qiu, Na Zhang, Ying-Yi Xu, Jing-Wen Qin, Gao-Feng Yu, Xing-Rong Song
Article Number: 74
Published online on: 22 December 2025

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ST3Gal1 modulates intestinal barrier function and impacts human ulcerative colitis

Yin Tian, Yun Liu, Yangyang Shang, Lijian Ran, Li Liu, Rongquan Wang, Jun Ye
Article Number: 73
Published online on: 18 December 2025

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Mechanistic study of miR‑369‑3p in regulating the Wnt/β‑catenin signaling pathway via targeting SPTBN1 in inflammatory response and bone destruction of rheumatoid arthritis

Aihong Wu, Yuan Wang, Feifei Liu, Zhoufang Cao, Shuhui Du, Mengyu Sun
Article Number: 72
Published online on: 18 December 2025

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CACNB1 alleviates mepivacaine‑induced myocardial ischemia/reperfusion injury by promoting Nrf2 nuclear translocation

Qingbo Shao, Ji Zhang, Huaying Wang
Article Number: 71
Published online on: 17 December 2025

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Expression of Concern Open Access

[Expression of Concern] Effects of cullin 4B on the proliferation and invasion of human gastric cancer cells

Feng He, Xiu-Mei Cheng, Wen-Long Gu
Article Number: 70
Published online on: 17 December 2025

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Article Open Access

Aggravated effects of human parvovirus B19 NS1 protein on bleomycin‑induced pulmonary fibrosis

Tsai-Ching Hsu, Chih-Chen Tzang, Chia-Wei Kuo, Zhi-Han Wen, Der-Yuan Chen, Bor-Show Tzang
Article Number: 69
Published online on: 16 December 2025

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Review Open Access

Advances regarding the mechanism of endoplasmic reticulum stress in diabetic kidney disease and pharmacological interventions (Review)

Pai Zhang, Yabin Cui, Chunyan Liu, Chengji Cui, Shoulin Zhang, Yue Zhang, Fan Li
Article Number: 68
Published online on: 16 December 2025

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Retraction Open Access

[Retracted] N‑Myc downstream‑regulated gene 2 suppresses the proliferation of T24 human bladder cancer cells via induction of oncosis

Jie Huang, Zhou Wu, Guangxiu Wang, Yingxian Cai, Minshan Cai, Yaozhang Li
Article Number: 67
Published online on: 15 December 2025

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Review Open Access

Deciphering epigenetic regulation in cardiac developmental toxicity: Mechanisms and implications (Review)

Ziling Qin, Ranran Chen, Dianrong Song
Article Number: 66
Published online on: 11 December 2025

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Review Open Access

Gut microbiota as a multifaceted modulator of prostate cancer: Mechanistic insights, therapeutic opportunities and clinical challenges (Review)

Zhenming Hao, Yongqiang Xie, Ru Zhang, Hui Sang, Luxi Li, Yulin Liu, Jinbo Hu, Jijun Wang, Keqiang Chai, Qiang Zhao
Article Number: 65
Published online on: 11 December 2025

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Expression of Concern Open Access

[Expression of Concern] lncRNA FLVCR1‑AS1 drives colorectal cancer progression via modulation of the miR‑381/RAP2A axis

Yi Han, Xiaoyan Wang, Enqiang Mao, Boyong Shen, Liang Huang
Article Number: 64
Published online on: 10 December 2025

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Review Open Access

Influence and treatment of insulin receptor substrate/PI3K/Akt‑mediated insulin resistance in diabetes mellitus (Review)

Weikang Tang, Huixia Liu, Xuan Li, Siyao Deng, Changyu Gao
Article Number: 63
Published online on: 09 December 2025

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Retraction Open Access

[Retracted] Long non‑coding RNA ANRIL knockdown suppresses apoptosis and pro‑inflammatory cytokines while enhancing neurite outgrowth via binding microRNA‑125a in a cellular model of Alzheimer’s disease

Bingling Zhou, Lijuan Li, Xin Qiu, Jiashun Wu, Lei Xu, Wei Shao
Article Number: 62
Published online on: 08 December 2025

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Review Open Access

Mitophagy and oxidative stress in chronic kidney disease (Review)

Quwu Mushuo, Yihuai Tian, Jianchun Li, Yanqin Qiu, Hui Fan, Qiongdan Hu, Qiong Zhang
Article Number: 61
Published online on: 04 December 2025

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Article Open Access

ABCC9 knockdown attenuates isoproterenol‑induced myocardial hypertrophy by inhibiting the PI3K/AKT signaling pathway

Qian Peng, Rui Chang, Linlin Ma, Yanfei Li
Article Number: 60
Published online on: 04 December 2025

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Article

MeCP2 suppresses ferroptosis to drive EMT in retinal pigment epithelial cells: Implications for PVR pathogenesis

Sibei Guo, Yongya Zhang, Xue Li, Xueru Zhao, Yingjuan Liang, Xiaohua Li
Article Number: 59
Published online on: 04 December 2025

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Correction Open Access

[Corrigendum] Screening for implicated genes in colorectal cancer using whole‑genome gene expression profiling

Long-Ci Sun, Hai-Xin Qian
Article Number: 58
Published online on: 04 December 2025

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Article Open Access

Hyperoside prevents osteoporosis by activating the PI3K/AKT signaling pathway to inhibit oxidative stress and promote osteogenesis

Lirong Li, Huaidong Deng, Shabin Zhuan, Boyu Wu, Dawei Xiao
Article Number: 57
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Interference with Tim‑3 protein expression attenuates the invasion of clear cell renal cell carcinoma and aggravates anoikis

Muming Yu, Bin Lu, Yancun Liu, Ying Me, Lijun Wang, Hui Li
Article Number: 56
Published online on: 01 December 2025

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Article Open Access

Acetylshikonin induces ferroptosis via the lipid peroxidation pathway in osteosarcoma cells

Ji-Ying Chen, Guo-Shou Wang, Tsung-Ming Chang, Ju-Fang Liu
Article Number: 55
Published online on: 27 November 2025

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Review Open Access

Liver X receptor: A potential target for inflammatory bowel disease and colorectal cancer (Review)

Yingjie Li, Xiaoyan Fu, Meiwen Bai, Jiaqi Zhou, Jiatai Qiu, Hongxia Zhang, Shujuan Liang, Meifang Liu
Article Number: 54
Published online on: 27 November 2025

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lncRNA NEAT1 promotes the proliferation of hemangioma cells by transcriptionally activating β‑catenin via enhancing H3K18 lactylation

Li Yu, Nian Zhou, Xiao-Liang Zhang, Xue-Jing Pang, Lu Xing, Yun-Jing Pu, Li Zhang, Jing-Nan Wu, Hong Shu
Article Number: 53
Published online on: 25 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑206 exerts anti‑oncogenic functions in esophageal squamous cell carcinoma by suppressing the c‑Met/AKT/mTOR pathway

Jin Zhang, Xianen Fa, Qingyong Zhang
Article Number: 52
Published online on: 25 November 2025

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Journal Cover
March-2026 Volume 33 Issue 3

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Retraction Open Access

[Retracted] Autophagy flux inhibition mediated by celastrol sensitized lung cancer cells to TRAIL‑induced apoptosis via regulation of mitochondrial transmembrane potential and reactive oxygen species

Uddin Md Nazim, Honghua Yin, Sang-Youel Park
Article Number: 94
Published online on: 19 January 2026

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Review Open Access

Converting ‘cold’ to ‘hot’ hepatocellular carcinoma for improved immunotherapy (Review)

Ching-Hua Hsieh, Pei-Chin Chuang
Article Number: 93
Published online on: 15 January 2026

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Article Open Access

Pathological mechanism of ferroptosis in a rat model of α‑naphthyl isothiocyanate‑induced chronic cholestasis

Zhen Guo, Jiaxuan Wang, Yiwen Wang, Xinzhu Liu, Yubing Xia, Ping Liu, Li Qi, Jia Liu, Xiaoning Wang
Article Number: 92
Published online on: 14 January 2026

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Correction Open Access

[Corrigendum] Role of hypoxia‑inducible factor‑1α and CD146 in epidermal growth factor receptor‑mediated angiogenesis in salivary gland adenoid cystic carcinom

Wei-Ming Wang, Zhi-Li Zhao, Wen-Feng Zhang, Yi-Fang Zhao, Lu Zhang, Zhi-Jun Sun
Article Number: 91
Published online on: 13 January 2026

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Klebsiella pneumoniae and pyogenic liver abscess: Emerging clinical threats, virulence mechanisms and therapeutic strategies (Review)

Gulam Mustafa Hasan, Taj Mohammad, Sobia Zaidi, Anas Shamsi, Sukhwinder Singh Sohal, Md. Imtaiyaz Hassan
Article Number: 90
Published online on: 13 January 2026

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Collagen III regulates the termination of liver regeneration by suppressing hepatocyte proliferation and promoting functional recovery

Haiyang Peng, Zhiyong Chen, Qiwei Zhang, Yuezhou Zhang, Peng Yang, Jianping Gong, Andong Zhao
Article Number: 89
Published online on: 13 January 2026

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Application of extracellular vesicles in the diagnosis and treatment of chronic obstructive pulmonary disease (Review)

Yixin Zhang, Tong Ren, Jianbo Xue, Yan Yu, Xianqiang Zhou, Xiaoyi Hu, Wenyi Yu, Zhancheng Gao, Cuiling Feng
Article Number: 88
Published online on: 13 January 2026

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Cigarette smoke combined with Klebsiella pneumoniae induce damage to the air‑blood barrier in chronic obstructive pulmonary disease rats via the MAPK/NF‑κB/IκBα pathway

Yange Tian, Kexin Xu, Ruilong Lu, Kangchen Li, Xuejie Shao, Yixi Liao, Yakun Zhao, Zhiguang Qiu, Haoran Dong, Xuefang Liu
Article Number: 87
Published online on: 12 January 2026

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Retraction Open Access

[Retracted] 8‑bromo‑7‑methoxychrysin induces apoptosis by regulating Akt/FOXO3a pathway in cisplatin‑sensitive and resistant ovarian cancer cells

Qing Ding, Yi Chen, Qing Zhang, Yanling Guo, Zhi Huang, Liqing Dai, Sudan Cao
Article Number: 86
Published online on: 12 January 2026

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Article Open Access

Anxiety‑induced overactive bladder: The role of oxidative stress and NF‑κB signaling pathway with Hsp90 as a potential biomarker

Zhipeng Zhou, Lina Xu, Han Wu, Huaishan Hong
Article Number: 85
Published online on: 12 January 2026

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Article Open Access

Echinacoside alleviates asthenozoospermia by upregulating Sox5‑mediated transcriptional activation of the CatSper gene

Zi-Run Jin, Yong-Wei Huo, Bo-Heng Liu, Hong Tian, Shuo Yuan, Yue Tian, Ke Xi, Jie Cai, Hui Jiang, Yong Jiang, Guo-Gang Xing
Article Number: 84
Published online on: 12 January 2026

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Article Open Access

Artemisiae Scopariae Herba (Yinchen) suppresses ferroptosis in mice with osteoporosis via the Nrf2/Slc7a11/Gpx4 pathway

Pei Li, Xinyu Wan, Wenjie Li, Ding Cheng, Ying Yang, Yuhan Wang, Ruyuan Zhu, Yanjing Chen, Haixia Liu, Zhiguo Zhang
Article Number: 83
Published online on: 12 January 2026

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Review Open Access

Prolyl hydroxylase domain proteins: Localization, regulation, function and their role in erythropoiesis (Review)

Yan Hou, Zhao-Hua Zhang, Wen-Qian Li, Guo-Xiong Han, Kuo Shen, You-Bang Xie
Article Number: 82
Published online on: 12 January 2026

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Review Open Access

Therapeutic potential of saponins for allergic rhinitis: Molecular mechanisms and clinical perspectives (Review)

Bing-Yu Liang, Zi-Yue Fu, Fen-Fen Li, Ping-Ting Zhou, Zi-Hui Xie, Ke Han, Yan-Xun Han, Shan-Wen Chen, Yi Zhao, Hai-Feng Pan, Ye-Hai Liu, Yu-Chen Liu
Article Number: 81
Published online on: 07 January 2026

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Interleukin‑6 and ischemic stroke: From mechanisms to clinical prospects (Review)

Xinyue Wang, Xiaohang Zhang, Jianing Lin, Ping Lin
Article Number: 80
Published online on: 05 January 2026

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Article Open Access

Preliminary exploration of the putative function of SF3A2 in clear cell renal cell carcinoma

Ru Chen, Jie Xu
Article Number: 79
Published online on: 05 January 2026

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Retraction Open Access

[Retracted] TIPE‑2 suppresses growth and aggressiveness of hepatocellular carcinoma cells through downregulation of the phosphoinositide 3‑kinase/AKT signaling pathway

Lin Wang, Chen Chen, Shuzhi Feng, Jianli Tian
Article Number: 78
Published online on: 05 January 2026

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