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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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International Journal of Molecular Medicine

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
2014-January Volume 33 Issue 1

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Journal Metrics

Impact Factor: 8.5

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review

Complex interaction between the immune system and adipose tissue (Review)

Sylwia Małgorzewicz, Jolanta Anna Dardzińska, Maria Gnacińska, Jerzy Jankun, Ewa Bryl, Krzysztof Sworczak
Pages: 3-7
Published online on: 25 October 2013

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Article Open Access

Thymoquinone regulates gene expression levels in the estrogen metabolic and interferon pathways in MCF7 breast cancer cells

Marjaneh Motaghed, Faisal Muti Al-Hassan, Shahrul Sahul Hamid
Pages: 8-16
Published online on: 21 November 2013

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Article Open Access

DMS triggers apoptosis associated with the inhibition of SPHK1/NF-κB activation and increase in intracellular Ca2+ concentration in human cancer cells

Kan Chen, Qiuwei Pan, Ying Gao, Xinyan Yang, Shibing Wang, Maikel P. Peppelenbosch, Xiangdong Kong
Pages: 17-24
Published online on: 30 October 2013

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Article Open Access

Integrated profiling of microRNA expression in membranous nephropathy using high-throughput sequencing technology

Wenbiao Chen, Xiaocong Lin, Jianrong Huang, Kuibi Tan, Yuyu Chen, Wujian Peng, Wuxian Li, Yong Dai
Pages: 25-34
Published online on: 12 November 2013

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Article Open Access

Destabilization of MYC/MYCN by the mitochondrial inhibitors, metaiodobenzylguanidine, metformin and phenformin

Stephanie S. Wang, Ruth Hsiao, Mariko M. Limpar, Sarah Lomahan, Tuan-Anh Tran, Nolan J. Maloney, Naohiko Ikegaki, Xao X. Tang
Pages: 35-42
Published online on: 01 November 2013

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Article Open Access

Characterization of microRNA expression profiles in patients with intervertebral disc degeneration

Bo Zhao, Qiang Yu, Haopeng Li, Xiong Guo, Xijing He
Pages: 43-50
Published online on: 30 October 2013

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Article Open Access

Metformin prevents hepatic steatosis by regulating the expression of adipose differentiation-related protein

Fang Liu, Chao Wang, Lijun Zhang, Yuqiao Xu, Lina Jang, Yu Gu, Xiangmei Cao, Xin Zhao, Jing Ye, Qing Li
Pages: 51-58
Published online on: 19 November 2013

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Article Open Access

Downregulation of miR-183 inhibits apoptosis and enhances the invasive potential of endometrial stromal cells in endometriosis

Xiao-Yan Shi, Lin Gu, Jie Chen, Xi-Rong Guo, Ying-Li Shi
Pages: 59-67
Published online on: 25 October 2013

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Article

Hypertension exacerbates liver injury and hepatic fibrosis induced by a choline-deficient L-amino acid-defined diet in rats

Shiho Arima, Hirofumi Uto, Rie Ibusuki, Ryo Kumamoto, Shirou Tanoue, Seiichi Mawatari, Kohei Oda, Masatsugu Numata, Hiroshi Fujita, Makoto Oketani, Akio Ido, Hirohito Tsubouchi
Pages: 68-76
Published online on: 01 November 2013

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Article

Detection of mitochondrial DNA mutations by high-throughput sequencing in the blood of breast cancer patients

Lin Hai Li, Tao Kang, Lidan Chen, Weiyun Zhang, Yang Liao, Jianyun Chen, Yuling Shi
Pages: 77-82
Published online on: 19 November 2013

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Article

The pathophysiological mechanisms underlying mucus hypersecretion induced by cold temperatures in cigarette smoke-exposed rats

Min-Chao Li, Gang Yang, Xiang-Dong Zhou, Sergey Tselluyko, Juliy M. Perelman
Pages: 83-90
Published online on: 23 October 2013

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Article

Cancer-associated fibroblasts enhance the migration ability of ovarian cancer cells by increasing EZH2 expression

Linjuan Xu, Qingchun Deng, Yinglian Pan, Minggang Peng, Xiaoling Wang, Limian Song, Man Xiao, Zehua Wang
Pages: 91-96
Published online on: 07 November 2013

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Article

C1q tumor necrosis factor-related protein-3 protects mesenchymal stem cells against hypoxia- and serum deprivation-induced apoptosis through the phosphoinositide 3-kinase/Akt pathway

Meng Hou, Jingjin Liu, Fang Liu, Kai Liu, Bo Yu
Pages: 97-104
Published online on: 07 November 2013

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Article

The effect of PS-341 on pulmonary vascular remodeling in high blood flow-induced pulmonary hypertension

Xue Zhang, Zong-Shuai Wang, Yun Luan, Mei Lin, Xiao-Bo Zhu, Yu Ma, Zhao-Hua Zhang, Yi-Biao Wang
Pages: 105-110
Published online on: 21 November 2013

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Article

Neuroglobin as a regulator of mitochondrial-dependent apoptosis: A bioinformatics analysis

Diego Guidolin, Luigi F. Agnati, Cinzia Tortorella, Manuela Marcoli, Guido Maura, Giovanna Albertin, Kjell Fuxe
Pages: 111-116
Published online on: 21 November 2013

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Article

Treatment of liver cancer in mice by the intratumoral injection of an octreotide-based temperature‑sensitive gel

Lili Zhang, Su Yu, Zhijun Duan, Qiuming Wang, Ge Tian, Yan Tian, Wei Zhao, Hui Wang, Cuiling Zhang, Shibin Guo, Qigui Liu, Gaohong He, Tengfei Bian, Jiuyang Chang, Xue Jin, Dongsheng Cui
Pages: 117-127
Published online on: 30 October 2013

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Article

Effects of mulberry ethanol extracts on hydrogen peroxide-induced oxidative stress in pancreatic β-cells

Young Rae Kim, Jong Seok Lee, Ki Rim Lee, Young Eon Kim, Nam In Baek, Eock Kee Hong
Pages: 128-134
Published online on: 23 October 2013

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Article

The effect of activin A on signal transduction pathways in PC12 cells subjected to oxygen and glucose deprivation

Hongliang Guo, Xiaoran Shen, Ye Xu, Youdi He, Wenli Hu
Pages: 135-141
Published online on: 30 October 2013

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Article

Inhibition of IL-32 and TSLP production through the attenuation of caspase-1 activation in an animal model of allergic rhinitis by Naju Jjok (Polygonum tinctorium)

Hyun-Ja Jeong, Hyun-A Oh, Byung-Joo Lee, Hyung-Min Kim
Pages: 142-150
Published online on: 05 November 2013

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Article

Epithelial-mesenchymal transition is necessary for acquired resistance to cisplatin and increases the metastatic potential of nasopharyngeal carcinoma cells Corrigendum in /10.3892/ijmm.2025.5591

Pei Zhang, Hao Liu, Fei Xia, Qian Wen Zhang, Yuan Yuan Zhang, Qing  Zhao, Zhen Hua Chao, Zhi Wen Jiang, Chen Chen Jiang
Pages: 151-159
Published online on: 30 October 2013

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Article

Evaluation of the effects of different culture media on the myogenic differentiation potential of adipose tissue- or bone marrow-derived human mesenchymal stem cells

Jens Stern-Straeter, Gabriel Alejandro Bonaterra, Stephanie Juritz, Richard Birk, Ulrich Reinhart Goessler, Karen Bieback, Peter Bugert, Johannes Schultz, Karl Hörmann, Ralf Kinscherf, Anne Faber
Pages: 160-170
Published online on: 13 November 2013

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Article

Recombinant AAV-PR39-mediated hypoxia-inducible factor 1α gene expression attenuates myocardial infarction

Lijun Sun, Yuewen Hao, Xiaowei Nie, Jian Xu, Zhenwu Li, Wei Zhang, Ying Liu, Xuexin Zhang
Pages: 171-177
Published online on: 19 November 2013

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Article

Increased OPG/RANKL ratio in the conditioned medium of soybean-treated osteoblasts suppresses RANKL-induced osteoclast differentiation

Kyungho Park, Won-Chul Ju, Joo-Hong Yeo, Jong Youl Kim, Ho Seong Seo, Yoshikazu Uchida, Yunhi Cho
Pages: 178-184
Published online on: 18 November 2013

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Article

Oridonin protects HaCaT keratinocytes against hydrogen peroxide-induced oxidative stress by altering microRNA expression

Seunghee Bae, Eun-Jin Lee, Jae  Ho Lee, In-Chul Park, Su-Jae Lee, Hyung Jin Hahn, Kyu Joong Ahn, Sungkwan An, In-Sook An, Hwa Jun Cha
Pages: 185-193
Published online on: 19 November 2013

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Article

P7 peptides targeting bFGF sensitize colorectal cancer cells to CPT-11

Wu Luo, Yonglin Yu, Ruixue Wang, Dan He, Cong Wang, Xiangfeng Zeng, Xilei Chen, Xiangpeng Tan, Tao Huang, Xiaoping Wu
Pages: 194-200
Published online on: 04 November 2013

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Article

Protective effects of nimodipine on cerebrovascular function in chronic alcoholic encephalopathy

Hui Li, Xue Yang, Wei Shi, Zhao Ma, Guangshen Feng, Qinzhou Wang, Li Shen, Chunli Xie
Pages: 201-208
Published online on: 30 October 2013

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Article

A novel ribonuclease with antiproliferative activity toward leukemia and lymphoma cells and HIV-1 reverse transcriptase inhibitory activity from the mushroom, Hohenbuehelia serotina

Rui  Zhang, Liyan  Zhao, Hexiang  Wang, Tzi  Bun Ng
Pages: 209-214
Published online on: 12 November 2013

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Article

In vitro assessment of the dual-targeting behavior of a peptide-based magnetic resonance imaging contrast agent

Yuping Yang, Kaichao Yu, Hailu Zhang, Jianwu Dai, Zongwu Deng
Pages: 215-220
Published online on: 07 November 2013

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Article

Effects of octylphenol on the expression of cell cycle-related genes and the growth of mesenchymal stem cells derived from human umbilical cord blood

Hye-Rim Lee, Tae-Hee Kim, Kelvin J. Choi, Kyung-Chul Choi
Pages: 221-226
Published online on: 14 November 2013

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Article

Huperzine A ameliorates damage induced by acute myocardial infarction in rats through antioxidant, anti-apoptotic and anti-inflammatory mechanisms

Xizhong Sui, Changqing Gao
Pages: 227-233
Published online on: 01 November 2013

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Article

Long-term administration of ginsenoside Rh1 enhances learning and memory by promoting cell survival in the mouse hippocampus

Jingang Hou, Jianjie Xue, Mira Lee, Jiaojiao Yu, Changkeun Sung
Pages: 234-240
Published online on: 08 November 2013

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Journal Cover
November-2026 Volume 58 Issue 5

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Journal Metrics

Impact Factor: 8.5

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

Spatial multi‑omics identifies an SPP1+ macrophage‑driven anti‑apoptotic niche in osteoarthritis synovium via the SPP1‑CD44 axis

Han Gong, Hao Shen, Feng Zhang, Wei Wang, Sheng Zhou, Lei Wang, Yu Sun
Article Number: 334
Published online on: 29 September 2026

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Review Open Access

Novel insights into the role of the renal interstitial microenvironment in Randall's plaque formation (Review)

Jialiang Wang, Zhangcheng Liao, Minghui Liu, Yizhou Wang, Yu Cui, Hequn Chen, Feng Zeng, Zewu Zhu
Article Number: 333
Published online on: 29 September 2026

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Correction Open Access

[Corrigendum] Alteration of the Wnt/GSK3β/β‑catenin signalling pathway by rapamycin ameliorates pathology in an Alzheimer's disease model

Jingfei Chen, Zhimin Long, Yanzhen Li, Min  Luo, Shifang  Luo, Guiqiong He
Article Number: 332
Published online on: 28 September 2026

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Article Open Access

miR‑222‑3p inhibits diabetic skin wound healing by targeting APLN

Ruyan Jie, Ying Tang, Tingting Wu, Chenfan Zhang, Man Song, Xiaotong Zhao, Mingwei Chen
Article Number: 331
Published online on: 25 September 2026

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Correction Open Access

[Corrigendum] Adjudin delays cellular senescence through Sirt3‑mediated attenuation of ROS production

Keyi Geng, Ningzhen Fu, Xiao Yang, Weiliang Xia
Article Number: 330
Published online on: 23 September 2026

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Article Open Access

Salidroside attenuates myocardial ischemia‑reperfusion‑induced oxidative stress and ferroptosis by promoting USP11‑mediated  deubiquitination of PRDX2

Zhi-Cong Qiu, Jian-Nan Li, Yi-Zhou Li, Zi-Ming Wu, Xu-Dong Luo, Rui-Yuan Zeng, Song-Qing Lai, Shi-Tao Zhao, Li Wan
Article Number: 329
Published online on: 23 September 2026

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Review Open Access

Reprogramming of cell death in gastric cancer: From molecular mechanisms to therapeutic potential (Review)

Mengru Liu, Zhujun Wu, Qiao Chen, Weiguo Ni, Ying Chen, Yixin Zhu, Yu Chen, Haifeng Ma, Yan Lin
Article Number: 328
Published online on: 23 September 2026

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Article Open Access

Remimazolam attenuates myocardial ischemia/reperfusion injury by inhibiting ferroptosis involving the AKT/SLC7A11/GPX4 axis

Xiyuan Chen, Jianghong Zhao, Xingtong He, Yuqi Zhang, Jiao Wu, Chao Jiang, Yi Yang, Ji Xiao
Article Number: 327
Published online on: 22 September 2026

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Review Open Access

Tumor‑immune spatiotemporal co‑evolution: A new paradigm for understanding and overcoming therapy resistance in metastatic castration‑resistant prostate cancer (Review)

Li Yan, Xiaoke Sun, Pengxiao Su
Article Number: 326
Published online on: 21 September 2026

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Review Open Access

Research progress on the role of IL‑37 in gynecological and obstetrics‑related diseases (Review)

Hongjing Wang, Renukha Arjune, Weiyu Gan, Na Guo, Nan Yu, Ting Xiong
Article Number: 325
Published online on: 21 September 2026

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Expression of Concern Open Access

[Expression of Concern] PAT protein mRNA expression in primary rat hepatocytes: Effects of exposure to fatty acids

Elena Grasselli, Adriana Voci, Carlo Pesce, Laura Canesi, Emilia Fugassa, Gabriella Gallo, Laura Vergani
Article Number: 324
Published online on: 21 September 2026

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Review Open Access

Neutrophil extracellular traps in cardiovascular disease: Mechanisms and therapeutic implications (Review)

Zhao Wang, Mingde Chang, Wenyu Shang, Yunfeng Jia, Xiaoyu Shan, Xinnong Chen, Yingxi Yang, Junping Zhang
Article Number: 323
Published online on: 18 September 2026

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Article Open Access

Sirt1 attenuates calcific aortic valve disease by inhibiting ferroptosis and enhancing mitochondrial function via the activation of the Nrf2/HO‑1/FTH1 axis

Fei Yan, Lei Shi, Yuechan Wang, Ying Zhao, Yuanyuan Wu, Dubiao Xian, Yunheng Liang, Ning Wang, Hongwang Cui, Minni Zhang
Article Number: 322
Published online on: 18 September 2026

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Article Open Access

Ketogenic diet attenuates Müller cell activation and retinal neuroinflammation in autoimmune glaucoma through acetylation‑mediated FOXO signalling

Sisi Tan, Xiaochen Wang, Yunfan Zheng, Zhenni Mou, Lihong Zeng, Jingchang Yuan, Xiao Fan, Miao Wei, Yujia Huo, Ruotong Ouyang, Yanyu Pu, Junqin Lei, Xi Gao, Dangdang Wang, Yang Peng, Hong Li
Article Number: 321
Published online on: 17 September 2026

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Review Open Access

ILC3s as central regulators of mucosal homeostasis and disease pathogenesis (Review)

Jingwen Zhang, Lili Bao, Jiaxi Li, Xia Li, Lu Qiao, Jiaxian Cui, Xiaoxia He, Mingyu Zhang, Jingkun Lu, Xuan Zhang, Jing Dong, Gesi Tao, Yaoqing Feng, Yun Peng Tian, Pengwei Zhao, Ya Tuo
Article Number: 320
Published online on: 17 September 2026

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Review Open Access

Small extracellular vesicles in osteoarthritis: A double‑edged sword regulating inflammation and cartilage homeostasis (Review)

Yifan Yang, Jiachen Liang, Xiangyu Shi, Anqi Niu, Ruifang Gao, Xiuping Wu, Xiaojuan Guo, Xiaotong Shi, Kejie Cao, Bing Li, Ran Li
Article Number: 319
Published online on: 17 September 2026

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Review Open Access

Exosomal circular RNAs in the tumor immune microenvironment: From regulatory mechanisms to therapeutic opportunities and translational hurdles (Review)

Wenlong Zhang, Nuo Chen, Liya Gong, Yu Dong, Hui Shen, Xin Liu, Jie Sun, Luxuan Liu, Zhe Jin, Liaoyuan Wang, Xue Han, Bin Zhang, Shuixing Zhang
Article Number: 318
Published online on: 17 September 2026

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Expression of Concern Open Access

[Expression of Concern] Ginsenoside Rg1 protects against H2O2‑induced neuronal damage due to inhibition of the NLRP1 inflammasome signalling pathway in hippocampal neurons in vitro

Tan-Zhen Xu, Xiao-Yan Shen, Ling-Ling Sun, Ya-Li Chen, Bi-Qiong Zhang, Da-Ke Huang, Wei-Zu Li
Article Number: 317
Published online on: 16 September 2026

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Review Open Access

tRNA‑derived RNAs in hepatic diseases: From biological functions to clinical translation (Review)

Yaotian Cai, Yifei Chen, Fuji Yang, Yongmin Yan, Ting Jiang
Article Number: 316
Published online on: 15 September 2026

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Review Open Access

Monocytes in pneumonia: Functional plasticity and innate memory (Review) 

Run-Ze Li, Zhi-Han Xie, Li Chen, Yun-Xiao Shang, Fei Wang, Wan-Jie Huang, Qi Cheng
Article Number: 315
Published online on: 15 September 2026

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Correction Open Access

[Corrigendum] Integrative transcriptomic analysis unveils FXR as a key regulator of intestinal stemness and inflammation in ulcerative colitis

Hao Lin, Xinran Cheng, Yangyang Ren, Yongmei Zhang, Weixu Chen, Qingyan Lu, Yiqing Tian
Article Number: 314
Published online on: 14 September 2026

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Review Open Access

Ferroptosis in heatstroke: Mechanisms and therapeutic perspectives (Review)

Hongguang Gao, Yang Chen, Tianshan Zhang, Yujun Shi, Rong Yao
Article Number: 313
Published online on: 10 September 2026

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Correction Open Access

[Corrigendum] Inactivation of von Hippel‑Lindau increases ovarian cancer cell aggressiveness through the HIF1α/miR‑210/VMP1 signaling pathway

Ting Liu, Le Zhao, Wei Chen, Zhen Li, Huilian Hou, Lu Ding, Xu Li
Article Number: 312
Published online on: 10 September 2026

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Review Open Access

Interferon regulatory factors orchestrate CD8+ T cell function (Review)

Fa-Xi Wang, Chun-Liang Yang, Shan-Jie Rong, Qi-Jie Chen, Xiong-Tao Yue, Fei Sun
Article Number: 311
Published online on: 08 September 2026

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Expression of Concern Open Access

[Expression of Concern] Rapamycin‑induced miR‑30a downregulation inhibits senescence of VSMCs by targeting Beclin1

Pan Tan, Haiqin Wang, Junkun Zhan, Xinyu Ma, Xingjun Cui, Yanjiao Wang, Yi Wang, Jiayu Zhong, Youshuo Liu
Article Number: 310
Published online on: 07 September 2026

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Review Open Access

Deciphering the function and mechanism of extracorporeal shock wave therapy in knee osteoarthritis (Review)

Yixuan Chen, Siqi Song, Yuchen Zhu, Shiqi Wang, Jieyuan Hu, Chenxu Liu, Yuchen Cai, Yushi Hu
Article Number: 309
Published online on: 04 September 2026

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Review Open Access

Multi‑omics integration in osteoarthritis: Unraveling cell‑type‑specific gene‑metabolite networks for precision medicine (Review)

Ying Yang, Ruichen Zheng, Yun Zhang, Dongmei Ye, Jiale Xie, Changliang Zhu
Article Number: 308
Published online on: 03 September 2026

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Review Open Access

Autophagy determines the fate of immune cells by regulating metabolic remodeling and PANoptosis (Review)

Yanan Guo, Xinyue Zhou, Yixiao Tian, Dan Chen, Xiaofeng Xie, Bin Zhou, Yingxia Tian, Yaqing Zhang
Article Number: 307
Published online on: 03 September 2026

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Review Open Access

Programmed cell death in metabolic syndrome: From molecular mechanisms to therapeutic strategies (Review)

Jialin Zhong, Maofu Zhang, Yafang Zheng, Cuicui Gong, Yasheng Deng, Lisha Sun, Dongqi Zhou, Qian Zhou, Qiu Chen
Article Number: 306
Published online on: 03 September 2026

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Review Open Access

Research progress on lysine acetylation (Review)

Minghui Zhang, Yuqi Zhang, Haoxin Yin, Junyuan Yan, Yingling Dong, Xin Zhao, Tianyi Cui, Bin Lv, Xiumei Gao
Article Number: 305
Published online on: 02 September 2026

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Expression of Concern Open Access

[Expression of Concern] Human ether‑à‑go‑go‑related gene mutation L539fs/47‑hERG leads to cell apoptosis through the endoplasmic reticulum stress pathway

Shuting Ma, Yun Zhao, Miaomiao Cao, Chaofeng Sun
Article Number: 304
Published online on: 02 September 2026

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Review Open Access

Targeting integrated cell death networks in sepsis‑associated acute kidney injury: Shared regulatory nodes and diet‑related small molecule modulation (Review)

Lin Song, Aifeng He, Wei Jiang, Keran Shi, Jing Wang, Lu Xu, Jiangquan Yu, Ruiqiang Zheng
Article Number: 303
Published online on: 31 August 2026

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Article Open Access

Effect of MALT1 inhibition by MI‑2 on the microglial phenotype switch, inflammatory cytokine secretion, neuronal loss and oxidative stress in Alzheimer's disease

Yuanlong Li, Hua Fan, Xiong Han, Ming Ni, Xiaodan Hou, Hailan Xia, Yinzhu Shi, Lin Zhang, Jun Sun
Article Number: 302
Published online on: 31 August 2026

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Review Open Access

Salvianolic acid monomers against metastasis: Decoding the multilayered interception of EMT, angiogenesis and immune evasion (Review)

Shiting Jiang, Dan Liu, Tingting Wei, Qiwei Shi, Haowen Wang, Yidan Gao, Pingsu Mao, Wenli Yang
Article Number: 301
Published online on: 31 August 2026

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Retraction Open Access

[Retracted] Silencing of decoy receptor 3 (DcR3) expression by siRNA in pancreatic carcinoma cells induces Fas ligand‑mediated apoptosis in vitro and in vivo

Jian Zhou, Shiduo Song, Songbin He, Zhenxin Wang, Bing Zhang, Dechun Li, Dongming Zhu
Article Number: 300
Published online on: 31 August 2026

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Review Open Access

Research progress on BTG2 in non‑tumor diseases (Review)

Shuling Li, Xiaomei Liu, Zheng Zhang, Ling Yang, Yuxuan Li, Qiongdan Hu
Article Number: 299
Published online on: 28 August 2026

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Review Open Access

Breaking the cycle of fibrosis: Ferroptosis as a therapeutic target (Review)

Xincheng Feng, Jue Zhang, Qinghong Ma, Chao Sun
Article Number: 298
Published online on: 27 August 2026

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Correction Open Access

[Corrigendum] Tumor‑targeting novel manganese complex induces ROS‑mediated apoptotic and autophagic cancer cell death

Jia Liu, Wenjie Guo, Jing Li, Xiang Li, Ji Geng, Qiuyun Chen, Jing Gao
Article Number: 297
Published online on: 26 August 2026

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Review Open Access

Advances in sirtuin research in lung diseases (Review)

Shuangyun Xi, Weijun Chen, Xiuli Li, Yudan Wang, Yong Ke
Article Number: 296
Published online on: 25 August 2026

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Article Open Access

lncRNA TUG1 mediates palmitic acid‑induced neuronal lipotoxic injury via the miR‑449a‑5p/caspase‑3 and Akt/GSK‑3β axes

Ya-Dong Wei, Peng-Quan Chen, Xin Zheng, Le-Qi Wu, Xin-Yi Wang, Xin-Ran Gao, Jin-Fang Ge
Article Number: 295
Published online on: 25 August 2026

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Retraction Open Access

[Retracted] Downregulation of LINC00707 promotes osteogenic differentiation of human bone marrow‑derived mesenchymal stem cells by regulating DKK1 via targeting miR‑103a‑3p

Jun Liu, Minfei Wu, Guang Feng, Rui Li, Yang Wang, Jianhang Jiao
Article Number: 294
Published online on: 24 August 2026

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December-2026 Volume 58 Issue 6

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Journal Metrics

Impact Factor: 8.5

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Protein S‑palmitoylation in T cell‑mediated antitumor immunity: Context‑dependent mechanisms and therapeutic opportunities (Review)

Shiting Wang, Rui Xu, Sikan Jin, Ting Yu, Ming Qin, Lin Xu, Xianyao Wang
Article Number: 367
Published online on: 04 November 2026

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Fatty acid‑binding proteins at the inflammation‑cancer interface: Isoform‑specific metabolic‑immune mechanisms and therapeutic implications (Review)

Young-Sool Hah, Young-Tae Ju, Seung-Jun Lee, Jeongyun Hwang, Seung-Jin Kwag
Article Number: 366
Published online on: 04 November 2026

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Review Open Access

Role of microglia in neuromyelitis optica (Review)

Yuan Zhang, Jian-Bin Hong, Ming-Wei Liu, Lin-Ming Zhang
Article Number: 365
Published online on: 03 November 2026

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Review Open Access

Roles of TRIM proteins in cardiovascular diseases: From pathogenesis to therapeutic targeting (Review)

Fengmei Wang, Zhibo Xing, Yujuan Gao, Yanhong Gai
Article Number: 364
Published online on: 02 November 2026

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Correction Open Access

[Corrigendum] S100A8‑targeting siRNA enhances arsenic trioxide‑induced myeloid leukemia cell death by down‑regulating autophagy

Liangchun Yang, Minghua Yang, Hong Zhang, Zhuo Wang, Yan Yu, Min Xie, Mingyi Zhao, Liying Liu, Lizhi Cao
Article Number: 363
Published online on: 02 November 2026

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Review Open Access

S100 proteins in kidney disease: Inflammatory biomarkers, pathogenic mechanisms and therapeutic prospects (Review)

Hongfei Wang, Zhaoyang Li, Qianqian Li, Yufang Ni, Lifeng Meng, Jianchun Li
Article Number: 362
Published online on: 30 October 2026

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Article

Mechanisms and therapeutic perspectives of mucosal glycosylation-innate immunity crosstalk in inflammatory bowel disease (Review)

Xiaowen Liu, Tao Zhang, Jiayi Jin, Yumeng Song, Mozhu Li, Haotong Zhong, Mingyue Cai, Siyuan Ding, Xiaowei Han
Article Number: 361
Published online on: 30 October 2026

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Review Open Access

Glycolysis in pulmonary fibrosis: From drivers to therapeutic opportunities (Review)

Changhong Yao, Huanyu Yang, Mengjia Han, Qi Xu
Article Number: 360
Published online on: 29 October 2026

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Correction Open Access

[Corrigendum] Exogenous spermine attenuates diabetic kidney injury in rats by inhibiting AMPK/mTOR signaling pathway

Xinying Zhang, Li Zhang, Zhe Chen, Siwei Li, Bingbing Che, Ningning Wang, Junting Chen, Changqing Xu, Can Wei
Article Number: 359
Published online on: 29 October 2026

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Review Open Access

Emerging role of non‑coding RNAs in the progression of MASLD‑driven hepatocellular carcinoma (Review)

Weihua Zheng, Caiyan An, Long Xia, Hongquan Wang, Yumin Wang, Junjing Zhang
Article Number: 358
Published online on: 27 October 2026

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Targeting ferroptosis in metabolic dysfunction‑associated steatotic liver disease: From mechanisms to cell type‑specific therapeutic strategies (Review)

Xiang Tao, Mei Liu
Article Number: 357
Published online on: 26 October 2026

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Review Open Access

Hormonal remodeling and molecular mechanisms in postmenopausal osteoporosis: Pathogenesis and therapeutic implications (Review)

Wenjun Liu, Zhengzheng Li, Penglin Wang, Jiahao Zeng, Haimin Zeng, Yining Xie, Ruhui Yang, Liu Yang, Sijian Lin, Chenyu Zhang
Article Number: 356
Published online on: 26 October 2026

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Correction Open Access

[Corrigendum] Apelin‑13 attenuates ER stress‑associated apoptosis induced by MPP+ in SH‑SY5Y cells 

Yunlu Jiang, Haiqing Liu, Bingyuan Ji, Zhengwen Wang, Chunmei Wang, Chunqing Yang, Yanyou Pan, Jing Chen, Baohua Cheng, Bo Bai
Article Number: 355
Published online on: 26 October 2026

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Review Open Access

Mechanisms and therapeutic implications of ferritinophagy in fibrotic diseases (Review)

Siying Sun, Jie Yu, Xuemei Li, Hongfei Liao
Article Number: 354
Published online on: 23 October 2026

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Review Open Access

Immune remodeling in inflammatory bowel disease-associated colorectal cancer: Mechanisms and immunotherapeutic implications (Review)

Tao Zhang, Zhetan Ren, Ling Wang, Ru Man, Lin Wang, Jing Wang, Xiaozhen Cheng, Jirun Peng, Yongduo Yu
Article Number: 353
Published online on: 22 October 2026

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Review Open Access

Inflammatory regulatory mechanisms and targeted therapy of antineutrophil cytoplasmic antibodies in atherosclerosis (Review)

Jingjing Cui, Qi Cui, Jinying Dou, Xiaoyan Li, Wenlong Chang, Lanchun Shi, Liyun An
Article Number: 352
Published online on: 22 October 2026

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Article Open Access

HMGN5 promotes renal tubular inflammation and pyroptosis‑associated signaling in chronic kidney disease via the IFNAR2 axis

Xue Rong, Jing Xu, Jienan Zhang, Qi Zhang, Jiangli Wang, Guoxin Zhang, Limin Nie
Article Number: 351
Published online on: 22 October 2026

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Correction Open Access

[Corrigendum] Radiation induces primary osteocyte senescence phenotype and affects osteoclastogenesis in vitro

Yuyang Wang, Linshan Xu, Jianping Wang, Jiangtao Bai, Jianglong Zhai, Guoying Zhu
Article Number: 350
Published online on: 21 October 2026

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Review Open Access

Transcription factors in liver fibrosis: Mechanistic insights and nanotechnology‑driven therapeutic strategies (Review)

Xianfei Zhou, Chongjun Yang, Zhiyong Weng, Lihua Li
Article Number: 349
Published online on: 21 October 2026

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Review Open Access

From RNA fate to cancer state transitions: m5C‑driven metabolic and immune reprogramming (Review)

Yuanli Zhou, Bolv Zhu, Xingzhou Tang, Shuishui Yin
Article Number: 348
Published online on: 20 October 2026

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Correction Open Access

[Corrigendum] Dihydroartemisinin attenuates osteoclast formation and bone resorption via inhibiting the NF‑κB, MAPK and NFATc1 signaling pathways and alleviates osteoarthritis 

Dong Ding, Jiangbo Yan, Gangning Feng, Yong Zhou, Long Ma, Qunhua Jin
Article Number: 347
Published online on: 19 October 2026

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Review Open Access

Centrosomal protein 55: Research progress on biological characteristics, disease associations and clinical translational potential (Review)

Sanmei Nong, Qiudong Huang, Kuibo Huang, Xiao Luo, Yin Huang, Wenlian Zheng, Weiyi Huang, Zhaoyun Liu
Article Number: 346
Published online on: 16 October 2026

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Review Open Access

Multiple strategies to improve the therapeutic efficacy of mesenchymal stem cell‑derived exosome transplantation in ischemic stroke (Review)

Yan Xu, Xiaolei Zhou, Wenhui Zeng, Jiabing Wang, Lin Zhou, Lincai Li, Zhengwei Zou, Cixiang Chen, Yichi Zhang, Zhengyi He, Junsong Ye
Article Number: 345
Published online on: 14 October 2026

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Article Open Access

Resveratrol alleviates osteoarthritis progression by inhibiting NLRP3 inflammasome response via the AMPK/PPARγ signaling pathway

Shanshan Cui, Zifan Luo, Wen Qin, Bo Chen, Qiaoxia Zhang, Jianbing Ma, Jie Ma, Rui Zhang
Article Number: 344
Published online on: 14 October 2026

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Expression of Concern Open Access

[Expression of Concern] Anti‑metastatic and differential effects on protein expression of epigallocatechin‑3‑gallate in HCCLM6 hepatocellular carcinoma cells

Yunjuan Zhang, Lawrence Owusu, Wei Duan, Tao Jiang, Shizhu Zang, Ayaz Ahmed, Yi Xin
Article Number: 343
Published online on: 14 October 2026

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Article Open Access

Six3 promoting the migration and neural differentiation of BMSCs via Btg2‑mediated Akt signaling pathway activation: A therapeutic strategy for stroke

Zhenqiang Fu, Zhixin Li, Limin Zhang, Wentao Hu, Hecheng Yang, Jingtao Wang
Article Number: 342
Published online on: 12 October 2026

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Expression of Concern Open Access

[Expression of Concern] EETs and CYP2J2 inhibit TNF‑α‑induced apoptosis in pulmonary artery endothelial cells and TGF‑β1‑induced migration in pulmonary artery smooth muscle cells

Wenjing Feng, Xizhen Xu, Gang Zhao, Geng Li, Tiantian Liu, Junjie Zhao, Ruolan Dong, Dao Wen Wang, Ling Tu
Article Number: 341
Published online on: 12 October 2026

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Review Open Access

Gomisin A as a multi‑target therapeutic agent: Pharmacological mechanisms, pharmacokinetics and network pharmacology (Review)

Jiaqi Xu, Sha Shi, Chengkai Zhu, Qi Sui, Shanhao Zhu, Jingnan Zhang, Yi Zhang, Peng Chen
Article Number: 340
Published online on: 09 October 2026

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Review Open Access

Multi‑target mechanisms of paeoniflorin in inflammatory regulation: A network pharmacology (Review)

Jin Zhang, Junjie Ye, Kun Jin, Xuan Sun, Xinyu Yu, Yuan Zhao, Ni Zhu
Article Number: 339
Published online on: 09 October 2026

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Review Open Access

Mechanisms of neuroimmune crosstalk in vestibular disorders: Linking inflammation with neural circuit dysfunction (Review)

Xianfang Pan, Jin Fan, Zhiyi Yang, Zegang Yin, Zhen Li, Zhifeng Rui, Hujun Zhang, Yujie Li, Hongjuan Zhang
Article Number: 338
Published online on: 08 October 2026

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Expression of Concern Open Access

[Expression of Concern] Gambogic acid inhibits invasion of osteosarcoma via upregulation of TIMP‑1

Zeng-Feng Xin, Cheng-Chun Shen, Li-Jiang Tao, Shi-Gui Yan, Hao-Bo Wu
Article Number: 337
Published online on: 08 October 2026

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Review Open Access

Anesthetics and cancer biology: Translational evidence from perioperative modulation to drug repurposing (Review)

Ting Yang, Jiao Tang, Muhammad Saqib Mudabbar, Huan Hu, Qiang Fu, Chunlan Pu
Article Number: 336
Published online on: 05 October 2026

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Expression of Concern Open Access

[Expression of Concern] Multiple roles of SOCS proteins: Differential expression of SOCS1 and SOCS3 in atherosclerosis

Xiao Liang, Ming He, Tao Chen, Yan Liu, Yu-Ling Tian, Yu-Liang Wu, Yan Zhao, Yan Shen, Zu-Yi Yuan
Article Number: 335
Published online on: 30 September 2026

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