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Molecular Medicine Reports
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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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February-2016 Volume 13 Issue 2

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Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Potential drawbacks in cell-assisted lipotransfer: A systematic review of existing reports (Review)

Sheng Huang, Weiliang Zhao, Zihua Wang, Kai Tao, Xiaoyan Liu, Peng Chang
Pages: 1063-1069
Published online on: 14 December 2015

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Article

Aloe vera and Vitis vinifera improve wound healing in an in vivo rat burn wound model

Li‑Xin Lin, Peng Wang, Yu‑Ting Wang, Yong Huang, Lei Jiang, Xue‑Ming Wang
Pages: 1070-1076
Published online on: 11 December 2015

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Article Open Access

Dendritic cells pulsed with Hsp70 and HBxAg induce specific antitumor immune responses in hepatitis B virus‑associated hepatocellular carcinoma

Hui Wang, Fang Feng, Xiao‑Ping Wang, Rou‑Shu Wang, Ying Wu, Min‑Gao Zhu, Hong Zhang, Zhi‑Xiang Zhuang
Pages: 1077-1082
Published online on: 07 December 2015

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Article Open Access

N‑methyl‑N‑nitro‑N'‑nitrosoguanidine induces the expression of CCR2 in human gastric epithelial cells promoting CCL2‑mediated migration

Jie Cai, Mei Wang, Mengchu Zhu, Qiang Zhang, Xu Zhang, Yongmin Yan, Hui Qian, Wenrong Xu
Pages: 1083-1090
Published online on: 07 December 2015

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Article Open Access

p53 causes butein‑mediated apoptosis of chronic myeloid leukemia cells

Sang‑Mi Woo, Youn Kynug Choi, Ah Jeong Kim, Sung‑Gook Cho, Seong‑Gyu Ko
Pages: 1091-1096
Published online on: 10 December 2015

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Article Open Access

Heterophyllin B inhibits the adhesion and invasion of ECA‑109 human esophageal carcinoma cells by targeting PI3K/AKT/β‑catenin signaling

Ji‑Cheng Tantai, Yao Zhang, Heng Zhao
Pages: 1097-1104
Published online on: 08 December 2015

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Article Open Access

TGF-β2 induces epithelial-mesenchymal transition in cultured human lens epithelial cells through activation of the PI3K/Akt/mTOR signaling pathway

Rui Guo, Qianli Meng, Haike Guo, Lijia Xiao, Xiaohong Yang, Ying Cui, Yu Huang
Pages: 1105-1110
Published online on: 04 December 2015

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Article Open Access

Sodium formate induces autophagy and apoptosis via the JNK signaling pathway of photoreceptor cells

Ying Wang, Shao‑Lin Xu, Wen‑Jing Xu, Hai‑Yan Yang, Ping Hu, Yu‑Xin Li
Pages: 1111-1118
Published online on: 11 December 2015

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Article Open Access

Molecular cloning and functional characterization of murine toll‑like receptor 8

Tingting Li, Xiaobing He, Huaijie Jia, Guohua Chen, Shuang Zeng, Yongxiang Fang, Qiwang Jin, Zhizhong Jing
Pages: 1119-1126
Published online on: 10 December 2015

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Article Open Access

Correlation between oxidative stress and the NF‑κB signaling pathway in the pulmonary tissues of obese asthmatic mice

Xiaomei Liu, Rongjun Lin, Baochun Zhao, Renzheng Guan, Tang Li, Rong Jin
Pages: 1127-1134
Published online on: 09 December 2015

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Article Open Access

X‑linked ichthyosis and Crigler‑Najjar syndrome Ⅰ: Coexistence in a male patient with two copy number variable regions of 2q37.1 and Xp22.3

Jinli Bai, Yujin Qu, Yanyan Cao, Yan Li, Wenhui Zhang, Yuwei Jin, Hong Wang, Fang Song
Pages: 1135-1140
Published online on: 10 December 2015

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Article Open Access

Anticancer effect of eupatilin on glioma cells through inhibition of the Notch-1 signaling pathway

Yawei Wang, Hongwei Hou, Ming Li, Yang Yang, Lan Sun
Pages: 1141-1146
Published online on: 10 December 2015

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Article Open Access

Effects of integrin α5β1 on the proliferation and migration of human aortic vascular smooth muscle cells

Yan Song, Xiaoyu Qin, Hanjie Wang, Renying Miao, Yonggan Zhang, Chaofeng Miao, Zifan Wang
Pages: 1147-1155
Published online on: 07 December 2015

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Article Open Access

AT1R blocker losartan attenuates intestinal epithelial cell apoptosis in a mouse model of Crohn's disease

Tian‑Jing Liu, Yong‑Yan Shi, En‑Bo Wang, Tong Zhu, Qun Zhao
Pages: 1156-1162
Published online on: 14 December 2015

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Article Open Access

Upregulation of the expression of Wnt5a promotes the proliferation of pancreatic cancer cells in vitro and in a nude mouse model

Haiji Bo, Li Gao, Ying Chen, Jing Zhang, Minghua Zhu
Pages: 1163-1171
Published online on: 04 December 2015

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Article Open Access

Identification of key genes in hepatocellular carcinoma and validation of the candidate gene, cdc25a, using gene set enrichment analysis, meta‑analysis and cross‑species comparison

Xiaoxu Lu, Wen Sun, Yanping Tang, Lingqun Zhu, Yuan Li, Chao Ou, Chun Yang, Jianjia Su, Chengpiao Luo, Yanling Hu, Ji Cao
Pages: 1172-1178
Published online on: 07 December 2015

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Article Open Access

CRMP‑5 interacts with actin to regulate neurite outgrowth

Xiaobing Gong, Minghui Tan, Yuan Gao, Keen Chen, Guoqing Guo
Pages: 1179-1185
Published online on: 09 December 2015

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Article Open Access

Vitamin D/VDR signaling attenuates lipopolysaccharide‑induced acute lung injury by maintaining the integrity of the pulmonary epithelial barrier

Yong‑Yan Shi, Tian‑Jing Liu, Jian‑Hua Fu, Wei Xu, Lin‑Lin Wu, A‑Na Hou, Xin‑Dong Xue
Pages: 1186-1194
Published online on: 14 December 2015

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Article Open Access

Differential lncRNA‑mRNA co‑expression network analysis revealing the potential regulatory roles of lncRNAs in myocardial infarction

Ping Wang, Haiying Fu, Jiayue Cui, Xia Chen
Pages: 1195-1203
Published online on: 10 December 2015

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Article Open Access

MicroRNA‑126 inhibits proliferation and metastasis by targeting pik3r2 in prostate cancer

Lei Song, Xubio Xie, Shaojie Yu, Fenghua Peng, Longkai Peng
Pages: 1204-1210
Published online on: 09 December 2015

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Article Open Access

Intravenous high mobility group box 1 upregulates the expression of HIF‑1α in the myocardium via a protein kinase B-dependent pathway in rats following acute myocardial ischemia

Heng‑Chen Yao, Min Zhou, Yan‑Hong Zhou, Lan‑Hua Wang, De‑Yong Zhang, Qian‑Feng Han, Tao Liu, Lei Wu, Ke‑Li Tian, Mei Zhang
Pages: 1211-1219
Published online on: 07 December 2015

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Article Open Access

Role of nitric oxide synthase in the development of bone cancer pain and effect of L‑NMMA

Yan Yang, Juan Zhang, Yue Liu, Yaguo Zheng, Jinhua Bo, Xiaofang Zhou, Junhua Wang, Zhengliang Ma
Pages: 1220-1226
Published online on: 07 December 2015

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Article Open Access

4‑Phenylbutyrate protects rat skin flaps against ischemia‑reperfusion injury and apoptosis by inhibiting endoplasmic reticulum stress

Zhen‑Shuang Yue, Lin‑Ru Zeng, Ren‑Fu Quan, Yang‑Hua Tang, Wen‑Jie Zheng, Gang Qu, Can‑Da Xu, Fang‑Bing Zhu, Zhong‑Ming Huang
Pages: 1227-1233
Published online on: 04 December 2015

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Article Open Access

Neurotrophin expression and laryngeal muscle pathophysiology following recurrent laryngeal nerve transection

Baoxin Wang, Junjie Yuan, Jiafeng Xu, Jin Xie, Guoliang Wang, Pin Dong
Pages: 1234-1242
Published online on: 14 December 2015

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Article

Induction of apoptosis in MCF‑7 human breast cancer cells by Khz (fusion of Ganoderma lucidum and Polyporus umbellatus mycelium)

Tae Hwan Kim, Ju Sung Kim, Zoo Haye Kim, Ren Bin Huang, Young Lye Chae, Ren Sheng Wang
Pages: 1243-1249
Published online on: 07 December 2015

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Article

Protective effect of C4a against hyperoxic lung injury via a macrophage‑dependent but not a neutrophil/lymphocyte‑dependent signaling pathway

Xiaoming Jiang, Yubo Ma, Jinfeng Yu, Haihong Li, Fengjie Xie
Pages: 1250-1256
Published online on: 07 December 2015

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Article

PI3K/Akt signaling pathway is involved in the neurotrophic effect of senegenin

Ting Pi, Xiao‑Wen Zhou, Liang Cai, Wei Zhang, Chao‑Fen Su, Wu‑Tian Wu, Xiao‑Ming Ren, Huan‑Min Luo
Pages: 1257-1262
Published online on: 07 December 2015

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Article

Tanshinone IIA decreases the migratory ability of AGS cells by decreasing the protein expression of matrix metalloproteinases, nuclear factor κB‑p65 and cyclooxygenase‑2

Chin‑Cheng Su
Pages: 1263-1268
Published online on: 08 December 2015

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Article

Inhibitor of DNA binding 4 functions as a tumor suppressor and is targetable by 5‑aza‑2'‑deoxycytosine with potential therapeutic significance in Burkitt's lymphoma

Xian‑Zheng Gao, Wu‑Gan Zhao, Guan‑Nan Wang, Mei‑Ying Cui, Yang‑Rui Zhang, Wen‑Cai Li
Pages: 1269-1274
Published online on: 04 December 2015

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Article

RBEL1 is required for osteosarcoma cell proliferation via inhibiting retinoblastoma 1

Honghui Tang, Feng Ji, Jin Sun, Yue Xie, Yongyi Xu, Haitao Yue
Pages: 1275-1280
Published online on: 10 December 2015

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Article

Resveratrol protects cardiomyocytes from doxorubicin‑induced apoptosis through the AMPK/P53 pathway

Mi‑Hua Liu, Xiao‑Long Lin, Dong‑Ming Guo, Yuan Zhang, Cong Yuan, Tian‑Ping Tan, Yu‑Dan Chen, Shao‑Jian Wu, Zu‑Feng Ye, Jun He
Pages: 1281-1286
Published online on: 09 December 2015

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Article

Tetramethylpyrazine protects CoCl2-induced apoptosis in human umbilical vein endothelial cells by regulating the PHD2/HIF/1α-VEGF pathway

Cheng Yang, Yue Xu, Huanjiao Zhou, Lu Yang, Shanshan Yu, Yi Gao, Yongsheng Huang, Lin Lu, Xiaoling Liang
Pages: 1287-1296
Published online on: 11 December 2015

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Article

MicroRNA‑7 suppresses human colon cancer invasion and proliferation by targeting the expression of focal adhesion kinase

Chun‑Yan Zeng, Yi‑Shan Zhan, Jun Huang, You‑Xiang Chen
Pages: 1297-1303
Published online on: 04 December 2015

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Article

Prehypertensive treatment with losartan, however not amlodipine, leads to long‑term effects on blood pressure and reduces the risk of stroke in spontaneously hypertensive stroke‑prone rats

Liangmin Zhang, Dehua He, Jinxiu Lin
Pages: 1304-1310
Published online on: 04 December 2015

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Article

Application of recombinant peroxisome proliferator‑activated receptor‑γ coactivator‑1α mediates neovascularization in the retina

Jian Jiang, Lixin Zhang, Lu Zhang, Xiaobo Xia
Pages: 1311-1319
Published online on: 11 December 2015

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Article

L‑carnitine ameliorates the liver inflammatory response by regulating carnitine palmitoyltransferase I‑dependent PPARγ signaling

Fang Jiang, Zongqi Zhang, Yi Zhang, Jianping Wu, Li Yu, Su Liu
Pages: 1320-1328
Published online on: 04 December 2015

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Article

Astrocytes protect glioma cells from chemotherapy and upregulate survival genes via gap junctional communication

Qingtang Lin, Zhao Liu, Feng Ling, Geng Xu
Pages: 1329-1335
Published online on: 11 December 2015

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Article

Chelidonine induces mitotic slippage and apoptotic-like death in SGC-7901 human gastric carcinoma cells

Zhongyuan Qu, Xiang Zou, Xiujuan Zhang, Jiejing Sheng, Yumeng Wang, Jiaqi Wang, Chao Wang, Yubin Ji
Pages: 1336-1344
Published online on: 14 December 2015

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Article

c-Jun N-terminal kinase inhibitor favors transforming growth factor‑β to antagonize hepatitis B virus X protein‑induced cell growth promotion in hepatocellular carcinoma

Yan‑Hui Wu, Xi Ai, Fu‑Yao Liu, Hui‑Fang Liang, Bi‑Xiang Zhang, Xiao‑Ping Chen
Pages: 1345-1352
Published online on: 04 December 2015

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Article

Honokiol protects against renal ischemia/reperfusion injury via the suppression of oxidative stress, iNOS, inflammation and STAT3 in rats

Yongwu Yu, Mingxv Li, Ning Su, Zhiyong Zhang, Haidan Zhao, Hai Yu, Yingluan Xu
Pages: 1353-1360
Published online on: 09 December 2015

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Article

Tumor suppressive microRNA‑429 regulates cellular function by targeting VEGF in clear cell renal cell carcinoma

Duqun Chen, Yuchi Li, Yifan Li, Lu Jin, Zhengming Su, Zuhu Yu, Shangqi Yang, Xiangming Mao, Yongqing Lai
Pages: 1361-1366
Published online on: 07 December 2015

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Article

Transforming growth factor‑β2 increases the capacity of retinal pigment epithelial cells to induce the generation of regulatory T cells

Feng Yan, Jin He, Li Tang, Yi Kong, Yuhua Shi, Suihua Chen, Zhenping Huang
Pages: 1367-1372
Published online on: 09 December 2015

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Article

1,25(OH)2D3 inhibits the progression of hepatocellular carcinoma via downregulating HDAC2 and upregulating P21(WAFI/CIP1)

Jian Huang, Guozhen Yang, Yunzhu Huang, Weiying Kong, Shu Zhang
Pages: 1373-1380
Published online on: 11 December 2015

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Article

Curcumin ameliorates dopaminergic neuronal oxidative damage via activation of the Akt/Nrf2 pathway

Qunli Cui, Xin Li, Hongcan Zhu
Pages: 1381-1388
Published online on: 08 December 2015

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Article

Tissue kallikrein promotes survival and β‑catenin degradation in SH‑SY5Y cells under nutrient stress conditions via autophagy

Yanping Liu, Mei Cui, Zhengyu Lu, Qi Yang, Qiang Dong
Pages: 1389-1394
Published online on: 09 December 2015

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Article

Dynamic regulation of effector IFN-γ-producing and IL-17-producing T cell subsets in the development of acute graft-versus-host disease

Kai Zhao, Suhong Ruan, Lingling Yin, Dongmei Zhao, Chong Chen, Bin Pan, Lingyu Zeng, Zhenyu Li, Kailin Xu
Pages: 1395-1403
Published online on: 04 December 2015

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Article

Integrative genomic analysis of interleukin‑36RN and its prognostic value in cancer

Zhilei Lv, Jinshuo Fan, Xiuxiu Zhang, Qi Huang, Jieli Han, Feng Wu, Guorong Hu, Mengfei Guo, Yang Jin
Pages: 1404-1412
Published online on: 09 December 2015

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Article

Role of autophagy on bone marrow mesenchymal stem‑cell proliferation and differentiation into neurons

Bo Li, Ping Duan, Caifang Li, Ying Jing, Xuefei Han, Wenhai Yan, Ying Xing
Pages: 1413-1419
Published online on: 10 December 2015

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Article

MicroRNA‑106b functions as an oncogene in renal cell carcinoma by affecting cell proliferation, migration and apoptosis

Yifan Li, Duqun Chen, Zhengming Su, Yuchi Li, Jiaju Liu, Lu Jin, Min Shi, Zhimao Jiang, Zhengyu Qi, Yaoting Gui, Shangqi Yang, Xiangming Mao, Xionghui Wu, Yongqing Lai
Pages: 1420-1426
Published online on: 08 December 2015

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Article

Knockdown of NogoA prevents MPP+‑induced neurotoxicity in PC12 cells via the mTOR/STAT3 signaling pathway

Jianbin Zhong, Xie Li, Limei Wan, Zhibang Chen, Simin Zhong, Songhua Xiao, Zhengwen Yan
Pages: 1427-1433
Published online on: 04 December 2015

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Article

Reduced proliferation and increased apoptosis of the SGC‑7901 gastric cancer cell line on exposure to GDC‑0449

Chuanqing Wu, Ji Cheng, Shaobo Hu, Rui Deng, Yamba Willy Muangu, Liang Shi, Ke Wu, Peng Zhang, Weilong Chang, Guobin Wang, Kaixiong Tao
Pages: 1434-1440
Published online on: 11 December 2015

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Review

Adenosine triphosphate-sensitive potassium channels and cardiomyopathies (Review)

Zhongwei Liu, Hui Cai, Yonghui Dang, Chuan Qiu, Junkui Wang
Pages: 1447-1454
Published online on: 23 December 2015

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Review

bZIP transmembrane transcription factor CREBH: Potential role in non‑alcoholic fatty liver disease (Review)

Min Wang, Shuiping Zhao, Mingyue Tan
Pages: 1455-1462
Published online on: 30 December 2015

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Review

Role of long noncoding RNAs in malignant disease (Review)

Ying Li, Xin Wang
Pages: 1463-1469
Published online on: 23 December 2015

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Review

Critical role of miRNAs in mediating skeletal muscle atrophy (Review)

Yonghui Yu, Wanli Chu, Jiake Chai, Xiao Li, Lingying Liu, Li Ma
Pages: 1470-1474
Published online on: 30 December 2015

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Article Open Access

Curcumin inhibits advanced glycation end product‑induced oxidative stress and inflammatory responses in endothelial cell damage via trapping methylglyoxal

Yan Ping Sun, Jun Fei Gu, Xiao Bin Tan, Chun Fei Wang, Xiao Bin Jia, Liang Feng, Ji Ping Liu
Pages: 1475-1486
Published online on: 28 December 2015

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Article Open Access

Caveolin‑1 is essential in the differentiation of human adipose‑derived stem cells into hepatocyte‑like cells via an MAPK pathway‑dependent mechanism

Xin Guan, Nan Wang, Fenggong Cui, Yang Liu, Peng Liu, Jingyuan Zhao, Chao Han, Xiaoyan Li, Zhiqian Leng, Ying Li, Xiaofei Ji, Wei Zou, Jing Liu
Pages: 1487-1494
Published online on: 30 December 2015

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Article Open Access

Dodecyl gallate induces apoptosis by upregulating the caspase-dependent apoptotic pathway and inhibiting the expression of anti-apoptotic Bcl-2 family proteins in human osteosarcoma cells

Chun‑Hsiang Cheng, Yen‑Po Cheng, Ing‑Lin Chang, Hsin‑Yao Chen, Chia‑Chieh Wu, Chen‑Pu Hsieh
Pages: 1495-1500
Published online on: 24 December 2015

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Article Open Access

Tanshinone IIA promotes the proliferation of WB‑F344 hepatic oval cells via Wnt/β‑catenin signaling

Xingyu Ze, Jidong Jia, Xinmin Li, Hong You, Xinyan Zhao, Dong Zhang, Baoen Wang
Pages: 1501-1508
Published online on: 18 December 2015

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Article Open Access

Vaspin attenuates the progression of atherosclerosis by inhibiting ER stress‑induced macrophage apoptosis in apoE‑/‑ mice

Ying Lin, Jianhui Zhuang, Hailing Li, Guofu Zhu, Shunping Zhou, Weiming Li, Wenhui Peng, Yawei Xu
Pages: 1509-1516
Published online on: 22 December 2015

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Article Open Access

Bone marrow‑derived mesenchymal stem cells rescue injured H9c2 cells via transferring intact mitochondria through tunneling nanotubes in an in vitro simulated ischemia/reperfusion model

Hui Han, Jinquan Hu, Qiang Yan, Jinzhou Zhu, Zhengbin Zhu, Yanjia Chen, Jiateng Sun, Ruiyan Zhang
Pages: 1517-1524
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Lei Chang, Cuicui Li, Tian Lan, Long Wu, Yufeng Yuan, Quanyan Liu, Zhisu Liu
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Ruinian Zheng, Zhijian You, Jun Jia, Shunhuan Lin, Shuai Han, Aixue Liu, Huidong Long, Senming Wang
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Selective regulation of neurosteroid biosynthesis under ketamine-induced apoptosis of cortical neurons in vitro

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Andrographolide inhibits multiple myeloma cells by inhibiting the TLR4/NF-κB signaling pathway

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Protective effects of black tea extract against oxidative DNA damage in human lymphocytes

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Investigations on the antifatigue and antihypoxic effects of Paecilomyces hepiali extract

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Survivin activates NF‑κB p65 via the IKKβ promoter in esophageal squamous cell carcinoma

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Expression profiles of inhibitor of growth protein 2 in normal and cancer tissues: An immunohistochemical screening analysis

Shuang Zhao, Xue‑Feng Yang, Wen‑Feng Gou, Hang Lu, Hua Li, Zhi‑Tu Zhu, Hong‑Zhi Sun, Hua‑Chuan Zheng
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Downregulation of connective tissue growth factor reduces migration and invasiveness of osteosarcoma cells

Yinjun Huang, Shichang Zhao, Changqing Zhang, Xiaolin Li
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MicroRNA-20b-5p functions as a tumor suppressor in renal cell carcinoma by regulating cellular proliferation, migration and apoptosis

Yifan Li, Duqun Chen, Lu Jin, Jiaju Liu, Zhengming Su, Yuchi Li, Yaoting Gui, Yongqing Lai
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Identification of miR‑130b as an oncogene in renal cell carcinoma

Yifan Li, Duqun Chen, Yuchi Li, Lu Jin, Jiaju Liu, Zhengming Su, Zhengyu Qi, Min Shi, Zhimao Jiang, Yaoting Gui, Shangqi Yang, Xiangming Mao, Yongqing Lai
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Type II cGMP-dependent protein kinase directly inhibits HER2 activation of gastric cancer cells

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Pages: 1909-1913
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Intrathecal injection of phosphodiesterase 4B-specific siRNA attenuates neuropathic pain in rats with L5 spinal nerve ligation

Qing Ji, Yan Di, Xiaoyun He, Qingzhen Liu, Jian Liu, Weiyan Li, Lidong Zhang
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MicroRNA-101 sensitizes hepatocellular carcinoma cells to doxorubicin-induced apoptosis via targeting Mcl-1

Haifei He, Wei Tian, Hailong Chen, Yongchuan Deng
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Zixun Dai, Jie Xie, Pengfei Lei, Yihe Hu
Pages: 1930-1936
Published online on: 28 December 2015

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Mucin 2 and unfolded protein response reshape the mucus barrier in inflammatory bowel disease (Review)

Zhiwei Yuan, Zheng Xia, Liyun Ling, Jingzhe Xie, Feng Zhang
Article Number: 18
Published online on: 29 October 2025

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RING finger protein family in leukemia (Review)

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Article Number: 17
Published online on: 29 October 2025

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Retinal light perception and biological rhythms: The role of light in sleep and mood from an ophthalmic perspective (Review)

Man Yuan, Hanxiang Liu, Ranjie Zhu, Yuzhen Li, Siyuan Song, Anhuai Yang
Article Number: 16
Published online on: 29 October 2025

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[Retracted] Oxymatrine‑mediated maturation of dendritic cells leads to activation of FOXP3+/CD4+ Treg cells and reversal of cisplatin‑resistance in lung cancer cells

Hui Liu, Manman Zou, Pei Li, Haifeng Wang, Xijun Lin, Jin Ye
Article Number: 15
Published online on: 27 October 2025

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Zinc finger protein 514 promotes esophageal cancer progression by enhancing cell proliferation, migration and invasion

Lin Lv, Xiaoming Sun, Houlu Zhang, Guangxu Wang, Chao Zhang, Haibo Liu, Liangming Zhu
Article Number: 14
Published online on: 24 October 2025

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Effects of zinc carnosine on bone loss in mice with diabetic osteoporosis 

Jingyuan Gao, Hao Yang, Qiangqiang Lian, Yunpeng Hu, Zhou Yang, Lei Xing, Ying Xue, Xiaoli Hou, Faming Tian, Dong Hu
Article Number: 13
Published online on: 24 October 2025

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Rapamycin improves endometriosis‑related infertility involving ovarian senescence via the PPARα/IGFBP2 pathway

Qiongwei Wu, Jiao Fan, Qingjing Sheng, Xiaoying He
Article Number: 12
Published online on: 24 October 2025

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Combining tadalafil and hyperbaric oxygen therapy protects against ovarian ischemia‑reperfusion damage in rats

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Published online on: 23 October 2025

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Liquid‑liquid phase separation of PHLDB2 promotes oral squamous cell carcinoma metastasis through regulating epithelial mesenchymal transition and PIK3CA expression

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Article Number: 10
Published online on: 22 October 2025

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Mitochondrial gatekeeper in hepatocellular carcinoma: Unraveling the multifaceted roles of VDAC in metabolic reprogramming, apoptosis evasion and therapeutic innovation (Review)

Jie Wang, Yu Liang, Xiaotao Jia, Xinmao Yang, Danning Shi, Yuanchun Wang, Yanfang Pan
Article Number: 9
Published online on: 21 October 2025

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[Retracted] Knockdown of ubiquitin‑specific protease 51 attenuates cisplatin resistance in lung cancer through ubiquitination of zinc‑finger E‑box binding homeobox 1

Feng Zhou, Chunling Du, Donghui Xu, Jinchang Lu, Lei Zhou, Chaomin Wu, Bo Wu, Jianan Huang
Article Number: 8
Published online on: 20 October 2025

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Exploring the role of cytochrome P450 family 1 subfamily B member 1 and quercetin in modulating neuropathic pain after spinal cord injury

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Published online on: 15 October 2025

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R‑loops in hepatocellular carcinoma: Bridging genomic instability and therapeutic opportunity (Review)

Ching-Hua Hsieh, Yueh-Wei Liu, Pei-Chin Chuang
Article Number: 6
Published online on: 15 October 2025

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Role and relevance of exosome-mediated epigenetic regulation in the pathogenesis, diagnosis and treatment of 
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Yishuo Zhang, Shanshan Zhang, Yijing Li, Wenqi Jin, Liya Zhou, Jing Lu
Article Number: 5
Published online on: 15 October 2025

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PLIN5 deficiency ameliorates metabolic dysfunction‑associated fatty liver disease by inhibiting ferroptosis

Ya Li, Xiaohan Wang, Xuecui Yin, Xiaohui Zhu, Weiqi Cui, Lin Dong, Yu Xia, Ying Wang, Liu Liu, Pengyuan Zheng, Youcai Tang
Article Number: 4
Published online on: 14 October 2025

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Circadian clock genes: Their influence on liver metabolism, disease development and treatment (Review)

Junmin Wang, Mengxing Cao, Shen Li, Wen Pei, Jing Li, Zhen Wang
Article Number: 3
Published online on: 14 October 2025

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MALT1 inhibition by MI‑2 suppresses epithelial‑to‑mesenchymal transition and fibrosis by inactivating the NF‑κB pathway in high glucose‑treated HK‑2 cells

Yating Lan, Jian Ma, Huijun Chen, Chaohong Lan, Na Zhao
Article Number: 2
Published online on: 14 October 2025

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[Retracted] Protective effect of erythropoietin against myocardial injury in rats with sepsis and its underlying mechanisms

Xinliang Zhang, Shimin Dong, Yanjun Qin, Xiaohua Bian
Article Number: 1
Published online on: 14 October 2025

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February-2026 Volume 33 Issue 2

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Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

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Mitophagy and oxidative stress in chronic kidney disease (Review)

Quwu Mushuo, Yihuai Tian, Jianchun Li, Yanqin Qiu, Hui Fan, Qiongdan Hu, Qiong Zhang
Article Number: 61
Published online on: 04 December 2025

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ABCC9 knockdown attenuates isoproterenol‑induced myocardial hypertrophy by inhibiting the PI3K/AKT signaling pathway

Qian Peng, Rui Chang, Linlin Ma, Yanfei Li
Article Number: 60
Published online on: 04 December 2025

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MeCP2 suppresses ferroptosis to drive EMT in retinal pigment epithelial cells: Implications for PVR pathogenesis

Sibei Guo, Yongya Zhang, Xue Li, Xueru Zhao, Yingjuan Liang, Xiaohua Li
Article Number: 59
Published online on: 04 December 2025

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[Corrigendum] Screening for implicated genes in colorectal cancer using whole‑genome gene expression profiling

Long-Ci Sun, Hai-Xin Qian
Article Number: 58
Published online on: 04 December 2025

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Hyperoside prevents osteoporosis by activating the PI3K/AKT signaling pathway to inhibit oxidative stress and promote osteogenesis

Lirong Li, Huaidong Deng, Shabin Zhuan, Boyu Wu, Dawei Xiao
Article Number: 57
Published online on: 03 December 2025

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[Retracted] Interference with Tim‑3 protein expression attenuates the invasion of clear cell renal cell carcinoma and aggravates anoikis

Muming Yu, Bin Lu, Yancun Liu, Ying Me, Lijun Wang, Hui Li
Article Number: 56
Published online on: 01 December 2025

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Acetylshikonin induces ferroptosis via the lipid peroxidation pathway in osteosarcoma cells

Ji-Ying Chen, Guo-Shou Wang, Tsung-Ming Chang, Ju-Fang Liu
Article Number: 55
Published online on: 27 November 2025

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Liver X receptor: A potential target for inflammatory bowel disease and colorectal cancer (Review)

Yingjie Li, Xiaoyan Fu, Meiwen Bai, Jiaqi Zhou, Jiatai Qiu, Hongxia Zhang, Shujuan Liang, Meifang Liu
Article Number: 54
Published online on: 27 November 2025

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lncRNA NEAT1 promotes the proliferation of hemangioma cells by transcriptionally activating β‑catenin via enhancing H3K18 lactylation

Li Yu, Nian Zhou, Xiao-Liang Zhang, Xue-Jing Pang, Lu Xing, Yun-Jing Pu, Li Zhang, Jing-Nan Wu, Hong Shu
Article Number: 53
Published online on: 25 November 2025

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[Retracted] MicroRNA‑206 exerts anti‑oncogenic functions in esophageal squamous cell carcinoma by suppressing the c‑Met/AKT/mTOR pathway

Jin Zhang, Xianen Fa, Qingyong Zhang
Article Number: 52
Published online on: 25 November 2025

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