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Molecular Medicine Reports
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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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February-2016 Volume 13 Issue 2

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Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Potential drawbacks in cell-assisted lipotransfer: A systematic review of existing reports (Review)

Sheng Huang, Weiliang Zhao, Zihua Wang, Kai Tao, Xiaoyan Liu, Peng Chang
Pages: 1063-1069
Published online on: 14 December 2015

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Article

Aloe vera and Vitis vinifera improve wound healing in an in vivo rat burn wound model

Li‑Xin Lin, Peng Wang, Yu‑Ting Wang, Yong Huang, Lei Jiang, Xue‑Ming Wang
Pages: 1070-1076
Published online on: 11 December 2015

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Article Open Access

Dendritic cells pulsed with Hsp70 and HBxAg induce specific antitumor immune responses in hepatitis B virus‑associated hepatocellular carcinoma

Hui Wang, Fang Feng, Xiao‑Ping Wang, Rou‑Shu Wang, Ying Wu, Min‑Gao Zhu, Hong Zhang, Zhi‑Xiang Zhuang
Pages: 1077-1082
Published online on: 07 December 2015

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Article Open Access

N‑methyl‑N‑nitro‑N'‑nitrosoguanidine induces the expression of CCR2 in human gastric epithelial cells promoting CCL2‑mediated migration

Jie Cai, Mei Wang, Mengchu Zhu, Qiang Zhang, Xu Zhang, Yongmin Yan, Hui Qian, Wenrong Xu
Pages: 1083-1090
Published online on: 07 December 2015

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Article Open Access

p53 causes butein‑mediated apoptosis of chronic myeloid leukemia cells

Sang‑Mi Woo, Youn Kynug Choi, Ah Jeong Kim, Sung‑Gook Cho, Seong‑Gyu Ko
Pages: 1091-1096
Published online on: 10 December 2015

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Article Open Access

Heterophyllin B inhibits the adhesion and invasion of ECA‑109 human esophageal carcinoma cells by targeting PI3K/AKT/β‑catenin signaling

Ji‑Cheng Tantai, Yao Zhang, Heng Zhao
Pages: 1097-1104
Published online on: 08 December 2015

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Article Open Access

TGF-β2 induces epithelial-mesenchymal transition in cultured human lens epithelial cells through activation of the PI3K/Akt/mTOR signaling pathway

Rui Guo, Qianli Meng, Haike Guo, Lijia Xiao, Xiaohong Yang, Ying Cui, Yu Huang
Pages: 1105-1110
Published online on: 04 December 2015

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Article Open Access

Sodium formate induces autophagy and apoptosis via the JNK signaling pathway of photoreceptor cells

Ying Wang, Shao‑Lin Xu, Wen‑Jing Xu, Hai‑Yan Yang, Ping Hu, Yu‑Xin Li
Pages: 1111-1118
Published online on: 11 December 2015

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Article Open Access

Molecular cloning and functional characterization of murine toll‑like receptor 8

Tingting Li, Xiaobing He, Huaijie Jia, Guohua Chen, Shuang Zeng, Yongxiang Fang, Qiwang Jin, Zhizhong Jing
Pages: 1119-1126
Published online on: 10 December 2015

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Article Open Access

Correlation between oxidative stress and the NF‑κB signaling pathway in the pulmonary tissues of obese asthmatic mice

Xiaomei Liu, Rongjun Lin, Baochun Zhao, Renzheng Guan, Tang Li, Rong Jin
Pages: 1127-1134
Published online on: 09 December 2015

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Article Open Access

X‑linked ichthyosis and Crigler‑Najjar syndrome Ⅰ: Coexistence in a male patient with two copy number variable regions of 2q37.1 and Xp22.3

Jinli Bai, Yujin Qu, Yanyan Cao, Yan Li, Wenhui Zhang, Yuwei Jin, Hong Wang, Fang Song
Pages: 1135-1140
Published online on: 10 December 2015

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Article Open Access

Anticancer effect of eupatilin on glioma cells through inhibition of the Notch-1 signaling pathway

Yawei Wang, Hongwei Hou, Ming Li, Yang Yang, Lan Sun
Pages: 1141-1146
Published online on: 10 December 2015

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Article Open Access

Effects of integrin α5β1 on the proliferation and migration of human aortic vascular smooth muscle cells

Yan Song, Xiaoyu Qin, Hanjie Wang, Renying Miao, Yonggan Zhang, Chaofeng Miao, Zifan Wang
Pages: 1147-1155
Published online on: 07 December 2015

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Article Open Access

AT1R blocker losartan attenuates intestinal epithelial cell apoptosis in a mouse model of Crohn's disease

Tian‑Jing Liu, Yong‑Yan Shi, En‑Bo Wang, Tong Zhu, Qun Zhao
Pages: 1156-1162
Published online on: 14 December 2015

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Article Open Access

Upregulation of the expression of Wnt5a promotes the proliferation of pancreatic cancer cells in vitro and in a nude mouse model

Haiji Bo, Li Gao, Ying Chen, Jing Zhang, Minghua Zhu
Pages: 1163-1171
Published online on: 04 December 2015

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Article Open Access

Identification of key genes in hepatocellular carcinoma and validation of the candidate gene, cdc25a, using gene set enrichment analysis, meta‑analysis and cross‑species comparison

Xiaoxu Lu, Wen Sun, Yanping Tang, Lingqun Zhu, Yuan Li, Chao Ou, Chun Yang, Jianjia Su, Chengpiao Luo, Yanling Hu, Ji Cao
Pages: 1172-1178
Published online on: 07 December 2015

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Article Open Access

CRMP‑5 interacts with actin to regulate neurite outgrowth

Xiaobing Gong, Minghui Tan, Yuan Gao, Keen Chen, Guoqing Guo
Pages: 1179-1185
Published online on: 09 December 2015

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Article Open Access

Vitamin D/VDR signaling attenuates lipopolysaccharide‑induced acute lung injury by maintaining the integrity of the pulmonary epithelial barrier

Yong‑Yan Shi, Tian‑Jing Liu, Jian‑Hua Fu, Wei Xu, Lin‑Lin Wu, A‑Na Hou, Xin‑Dong Xue
Pages: 1186-1194
Published online on: 14 December 2015

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Article Open Access

Differential lncRNA‑mRNA co‑expression network analysis revealing the potential regulatory roles of lncRNAs in myocardial infarction

Ping Wang, Haiying Fu, Jiayue Cui, Xia Chen
Pages: 1195-1203
Published online on: 10 December 2015

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Article Open Access

MicroRNA‑126 inhibits proliferation and metastasis by targeting pik3r2 in prostate cancer

Lei Song, Xubio Xie, Shaojie Yu, Fenghua Peng, Longkai Peng
Pages: 1204-1210
Published online on: 09 December 2015

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Article Open Access

Intravenous high mobility group box 1 upregulates the expression of HIF‑1α in the myocardium via a protein kinase B-dependent pathway in rats following acute myocardial ischemia

Heng‑Chen Yao, Min Zhou, Yan‑Hong Zhou, Lan‑Hua Wang, De‑Yong Zhang, Qian‑Feng Han, Tao Liu, Lei Wu, Ke‑Li Tian, Mei Zhang
Pages: 1211-1219
Published online on: 07 December 2015

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Article Open Access

Role of nitric oxide synthase in the development of bone cancer pain and effect of L‑NMMA

Yan Yang, Juan Zhang, Yue Liu, Yaguo Zheng, Jinhua Bo, Xiaofang Zhou, Junhua Wang, Zhengliang Ma
Pages: 1220-1226
Published online on: 07 December 2015

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Article Open Access

4‑Phenylbutyrate protects rat skin flaps against ischemia‑reperfusion injury and apoptosis by inhibiting endoplasmic reticulum stress

Zhen‑Shuang Yue, Lin‑Ru Zeng, Ren‑Fu Quan, Yang‑Hua Tang, Wen‑Jie Zheng, Gang Qu, Can‑Da Xu, Fang‑Bing Zhu, Zhong‑Ming Huang
Pages: 1227-1233
Published online on: 04 December 2015

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Article Open Access

Neurotrophin expression and laryngeal muscle pathophysiology following recurrent laryngeal nerve transection

Baoxin Wang, Junjie Yuan, Jiafeng Xu, Jin Xie, Guoliang Wang, Pin Dong
Pages: 1234-1242
Published online on: 14 December 2015

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Article

Induction of apoptosis in MCF‑7 human breast cancer cells by Khz (fusion of Ganoderma lucidum and Polyporus umbellatus mycelium)

Tae Hwan Kim, Ju Sung Kim, Zoo Haye Kim, Ren Bin Huang, Young Lye Chae, Ren Sheng Wang
Pages: 1243-1249
Published online on: 07 December 2015

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Article

Protective effect of C4a against hyperoxic lung injury via a macrophage‑dependent but not a neutrophil/lymphocyte‑dependent signaling pathway

Xiaoming Jiang, Yubo Ma, Jinfeng Yu, Haihong Li, Fengjie Xie
Pages: 1250-1256
Published online on: 07 December 2015

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Article

PI3K/Akt signaling pathway is involved in the neurotrophic effect of senegenin

Ting Pi, Xiao‑Wen Zhou, Liang Cai, Wei Zhang, Chao‑Fen Su, Wu‑Tian Wu, Xiao‑Ming Ren, Huan‑Min Luo
Pages: 1257-1262
Published online on: 07 December 2015

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Article

Tanshinone IIA decreases the migratory ability of AGS cells by decreasing the protein expression of matrix metalloproteinases, nuclear factor κB‑p65 and cyclooxygenase‑2

Chin‑Cheng Su
Pages: 1263-1268
Published online on: 08 December 2015

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Article

Inhibitor of DNA binding 4 functions as a tumor suppressor and is targetable by 5‑aza‑2'‑deoxycytosine with potential therapeutic significance in Burkitt's lymphoma

Xian‑Zheng Gao, Wu‑Gan Zhao, Guan‑Nan Wang, Mei‑Ying Cui, Yang‑Rui Zhang, Wen‑Cai Li
Pages: 1269-1274
Published online on: 04 December 2015

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Article

RBEL1 is required for osteosarcoma cell proliferation via inhibiting retinoblastoma 1

Honghui Tang, Feng Ji, Jin Sun, Yue Xie, Yongyi Xu, Haitao Yue
Pages: 1275-1280
Published online on: 10 December 2015

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Article

Resveratrol protects cardiomyocytes from doxorubicin‑induced apoptosis through the AMPK/P53 pathway

Mi‑Hua Liu, Xiao‑Long Lin, Dong‑Ming Guo, Yuan Zhang, Cong Yuan, Tian‑Ping Tan, Yu‑Dan Chen, Shao‑Jian Wu, Zu‑Feng Ye, Jun He
Pages: 1281-1286
Published online on: 09 December 2015

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Article

Tetramethylpyrazine protects CoCl2-induced apoptosis in human umbilical vein endothelial cells by regulating the PHD2/HIF/1α-VEGF pathway

Cheng Yang, Yue Xu, Huanjiao Zhou, Lu Yang, Shanshan Yu, Yi Gao, Yongsheng Huang, Lin Lu, Xiaoling Liang
Pages: 1287-1296
Published online on: 11 December 2015

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Article

MicroRNA‑7 suppresses human colon cancer invasion and proliferation by targeting the expression of focal adhesion kinase

Chun‑Yan Zeng, Yi‑Shan Zhan, Jun Huang, You‑Xiang Chen
Pages: 1297-1303
Published online on: 04 December 2015

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Article

Prehypertensive treatment with losartan, however not amlodipine, leads to long‑term effects on blood pressure and reduces the risk of stroke in spontaneously hypertensive stroke‑prone rats

Liangmin Zhang, Dehua He, Jinxiu Lin
Pages: 1304-1310
Published online on: 04 December 2015

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Article

Application of recombinant peroxisome proliferator‑activated receptor‑γ coactivator‑1α mediates neovascularization in the retina

Jian Jiang, Lixin Zhang, Lu Zhang, Xiaobo Xia
Pages: 1311-1319
Published online on: 11 December 2015

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Article

L‑carnitine ameliorates the liver inflammatory response by regulating carnitine palmitoyltransferase I‑dependent PPARγ signaling

Fang Jiang, Zongqi Zhang, Yi Zhang, Jianping Wu, Li Yu, Su Liu
Pages: 1320-1328
Published online on: 04 December 2015

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Article

Astrocytes protect glioma cells from chemotherapy and upregulate survival genes via gap junctional communication

Qingtang Lin, Zhao Liu, Feng Ling, Geng Xu
Pages: 1329-1335
Published online on: 11 December 2015

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Article

Chelidonine induces mitotic slippage and apoptotic-like death in SGC-7901 human gastric carcinoma cells

Zhongyuan Qu, Xiang Zou, Xiujuan Zhang, Jiejing Sheng, Yumeng Wang, Jiaqi Wang, Chao Wang, Yubin Ji
Pages: 1336-1344
Published online on: 14 December 2015

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Article

c-Jun N-terminal kinase inhibitor favors transforming growth factor‑β to antagonize hepatitis B virus X protein‑induced cell growth promotion in hepatocellular carcinoma

Yan‑Hui Wu, Xi Ai, Fu‑Yao Liu, Hui‑Fang Liang, Bi‑Xiang Zhang, Xiao‑Ping Chen
Pages: 1345-1352
Published online on: 04 December 2015

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Article

Honokiol protects against renal ischemia/reperfusion injury via the suppression of oxidative stress, iNOS, inflammation and STAT3 in rats

Yongwu Yu, Mingxv Li, Ning Su, Zhiyong Zhang, Haidan Zhao, Hai Yu, Yingluan Xu
Pages: 1353-1360
Published online on: 09 December 2015

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Article

Tumor suppressive microRNA‑429 regulates cellular function by targeting VEGF in clear cell renal cell carcinoma

Duqun Chen, Yuchi Li, Yifan Li, Lu Jin, Zhengming Su, Zuhu Yu, Shangqi Yang, Xiangming Mao, Yongqing Lai
Pages: 1361-1366
Published online on: 07 December 2015

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Article

Transforming growth factor‑β2 increases the capacity of retinal pigment epithelial cells to induce the generation of regulatory T cells

Feng Yan, Jin He, Li Tang, Yi Kong, Yuhua Shi, Suihua Chen, Zhenping Huang
Pages: 1367-1372
Published online on: 09 December 2015

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Article

1,25(OH)2D3 inhibits the progression of hepatocellular carcinoma via downregulating HDAC2 and upregulating P21(WAFI/CIP1)

Jian Huang, Guozhen Yang, Yunzhu Huang, Weiying Kong, Shu Zhang
Pages: 1373-1380
Published online on: 11 December 2015

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Article

Curcumin ameliorates dopaminergic neuronal oxidative damage via activation of the Akt/Nrf2 pathway

Qunli Cui, Xin Li, Hongcan Zhu
Pages: 1381-1388
Published online on: 08 December 2015

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Article

Tissue kallikrein promotes survival and β‑catenin degradation in SH‑SY5Y cells under nutrient stress conditions via autophagy

Yanping Liu, Mei Cui, Zhengyu Lu, Qi Yang, Qiang Dong
Pages: 1389-1394
Published online on: 09 December 2015

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Article

Dynamic regulation of effector IFN-γ-producing and IL-17-producing T cell subsets in the development of acute graft-versus-host disease

Kai Zhao, Suhong Ruan, Lingling Yin, Dongmei Zhao, Chong Chen, Bin Pan, Lingyu Zeng, Zhenyu Li, Kailin Xu
Pages: 1395-1403
Published online on: 04 December 2015

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Article

Integrative genomic analysis of interleukin‑36RN and its prognostic value in cancer

Zhilei Lv, Jinshuo Fan, Xiuxiu Zhang, Qi Huang, Jieli Han, Feng Wu, Guorong Hu, Mengfei Guo, Yang Jin
Pages: 1404-1412
Published online on: 09 December 2015

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Article

Role of autophagy on bone marrow mesenchymal stem‑cell proliferation and differentiation into neurons

Bo Li, Ping Duan, Caifang Li, Ying Jing, Xuefei Han, Wenhai Yan, Ying Xing
Pages: 1413-1419
Published online on: 10 December 2015

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Article

MicroRNA‑106b functions as an oncogene in renal cell carcinoma by affecting cell proliferation, migration and apoptosis

Yifan Li, Duqun Chen, Zhengming Su, Yuchi Li, Jiaju Liu, Lu Jin, Min Shi, Zhimao Jiang, Zhengyu Qi, Yaoting Gui, Shangqi Yang, Xiangming Mao, Xionghui Wu, Yongqing Lai
Pages: 1420-1426
Published online on: 08 December 2015

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Article

Knockdown of NogoA prevents MPP+‑induced neurotoxicity in PC12 cells via the mTOR/STAT3 signaling pathway

Jianbin Zhong, Xie Li, Limei Wan, Zhibang Chen, Simin Zhong, Songhua Xiao, Zhengwen Yan
Pages: 1427-1433
Published online on: 04 December 2015

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Article

Reduced proliferation and increased apoptosis of the SGC‑7901 gastric cancer cell line on exposure to GDC‑0449

Chuanqing Wu, Ji Cheng, Shaobo Hu, Rui Deng, Yamba Willy Muangu, Liang Shi, Ke Wu, Peng Zhang, Weilong Chang, Guobin Wang, Kaixiong Tao
Pages: 1434-1440
Published online on: 11 December 2015

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Review

Adenosine triphosphate-sensitive potassium channels and cardiomyopathies (Review)

Zhongwei Liu, Hui Cai, Yonghui Dang, Chuan Qiu, Junkui Wang
Pages: 1447-1454
Published online on: 23 December 2015

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Review

bZIP transmembrane transcription factor CREBH: Potential role in non‑alcoholic fatty liver disease (Review)

Min Wang, Shuiping Zhao, Mingyue Tan
Pages: 1455-1462
Published online on: 30 December 2015

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Review

Role of long noncoding RNAs in malignant disease (Review)

Ying Li, Xin Wang
Pages: 1463-1469
Published online on: 23 December 2015

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Review

Critical role of miRNAs in mediating skeletal muscle atrophy (Review)

Yonghui Yu, Wanli Chu, Jiake Chai, Xiao Li, Lingying Liu, Li Ma
Pages: 1470-1474
Published online on: 30 December 2015

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Article Open Access

Curcumin inhibits advanced glycation end product‑induced oxidative stress and inflammatory responses in endothelial cell damage via trapping methylglyoxal

Yan Ping Sun, Jun Fei Gu, Xiao Bin Tan, Chun Fei Wang, Xiao Bin Jia, Liang Feng, Ji Ping Liu
Pages: 1475-1486
Published online on: 28 December 2015

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Article Open Access

Caveolin‑1 is essential in the differentiation of human adipose‑derived stem cells into hepatocyte‑like cells via an MAPK pathway‑dependent mechanism

Xin Guan, Nan Wang, Fenggong Cui, Yang Liu, Peng Liu, Jingyuan Zhao, Chao Han, Xiaoyan Li, Zhiqian Leng, Ying Li, Xiaofei Ji, Wei Zou, Jing Liu
Pages: 1487-1494
Published online on: 30 December 2015

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Article Open Access

Dodecyl gallate induces apoptosis by upregulating the caspase-dependent apoptotic pathway and inhibiting the expression of anti-apoptotic Bcl-2 family proteins in human osteosarcoma cells

Chun‑Hsiang Cheng, Yen‑Po Cheng, Ing‑Lin Chang, Hsin‑Yao Chen, Chia‑Chieh Wu, Chen‑Pu Hsieh
Pages: 1495-1500
Published online on: 24 December 2015

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Article Open Access

Tanshinone IIA promotes the proliferation of WB‑F344 hepatic oval cells via Wnt/β‑catenin signaling

Xingyu Ze, Jidong Jia, Xinmin Li, Hong You, Xinyan Zhao, Dong Zhang, Baoen Wang
Pages: 1501-1508
Published online on: 18 December 2015

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Article Open Access

Vaspin attenuates the progression of atherosclerosis by inhibiting ER stress‑induced macrophage apoptosis in apoE‑/‑ mice

Ying Lin, Jianhui Zhuang, Hailing Li, Guofu Zhu, Shunping Zhou, Weiming Li, Wenhui Peng, Yawei Xu
Pages: 1509-1516
Published online on: 22 December 2015

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Article Open Access

Bone marrow‑derived mesenchymal stem cells rescue injured H9c2 cells via transferring intact mitochondria through tunneling nanotubes in an in vitro simulated ischemia/reperfusion model

Hui Han, Jinquan Hu, Qiang Yan, Jinzhou Zhu, Zhengbin Zhu, Yanjia Chen, Jiateng Sun, Ruiyan Zhang
Pages: 1517-1524
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Intestinal injury following liver transplantation was mediated by TLR4/NF-κB activation-induced cell apoptosis

Dong‑Dong Yuan, Xin‑Jin Chi, Yi Jin, Xi Li, Mian Ge, Wan‑Ling Gao, Jian‑Qiang Guan, Ai‑Lan Zhang, Zi‑Qing Hei
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Inhibition of ERK1/2 improves lipid balance in rat macrophages via ABCA1/G1 and CD36

Xie‑Hua Xue, Feng‑Fei Shi, Tong Chen, Wei Wei, Xiao‑Mao Zhou, Li‑Dian Chen
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Decreased expression of long non-coding RNA GAS5 indicates a poor prognosis and promotes cell proliferation and invasion in hepatocellular carcinoma by regulating vimentin

Lei Chang, Cuicui Li, Tian Lan, Long Wu, Yufeng Yuan, Quanyan Liu, Zhisu Liu
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Clinicopathological significance of vascular endothelial growth factor, thymidine phosphorylase and microvessel density in colorectal cancer

Yutaka Kimura, Satoko Morohashi, Tadashi Yoshizawa, Takahiro Suzuki, Hajime Morohashi, Yoshiyuki Sakamoto, Motoi Koyama, Akihiko Murata, Hiroshi Kijima, Kenichi Hakamada
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Anti‑carcinogenic activity of anandamide on human glioma in vitro and in vivo Retraction in /10.3892/mmr.2023.12969

Chao Ma, Ting‑Ting Wu, Pu‑Cha Jiang, Zhi‑Qiang Li, Xin‑Jun Chen, Kai Fu, Wei Wang, Rui Gong
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Interleukin‑6 induces epithelial‑mesenchymal transition in human intrahepatic biliary epithelial cells

Gui‑Xing Jiang, Li‑Ping Cao, Peng‑Cheng Kang, Xiang‑Yu Zhong, Tian‑Yu Lin, Yun‑Fu Cui
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Curcumin enhances the antitumor effect of ABT-737 via activation of the ROS-ASK1-JNK pathway in hepatocellular carcinoma cells

Ruinian Zheng, Zhijian You, Jun Jia, Shunhuan Lin, Shuai Han, Aixue Liu, Huidong Long, Senming Wang
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TRPC6 is required for hypoxia‑induced basal intracellular calcium concentration elevation, and for the proliferation and migration of rat distal pulmonary venous smooth muscle cells

Qingjie Wang, Dong Wang, Gaoling Yan, Ling Sun, Chengchun Tang
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Selective regulation of neurosteroid biosynthesis under ketamine-induced apoptosis of cortical neurons in vitro

Jianli Li, Yang Yu, Bei Wang, Honghai Wu, Gai Xue, Yanning Hou
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Glucagon‑like peptide‑1 protects cardiomyocytes from advanced oxidation protein product‑induced apoptosis via the PI3K/Akt/Bad signaling pathway

Hua Zhang, Zhouyi Xiong, Jiao Wang, Shuangshuang Zhang, Lei Lei, Li Yang, Zhen Zhang
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Targeting survivin using a combination of miR‑494 and survivin shRNA has synergistic effects on the suppression of prostate cancer growth

Jin Zhu, Chenwen Sun, Liping Wang, Ming Xu, Yachen Zang, Yibin Zhou, Xiaolong Liu, Wei Tao, Boxin Xue, Yuxi Shan, Dongrong Yang
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Electroacupuncture at the Baihui acupoint alleviates cognitive impairment and exerts neuroprotective effects by modulating the expression and processing of brain‑derived neurotrophic factor in APP/PS1 transgenic mice

Ruhui Lin, Jixiang Chen, Xiaojie Li, Jingjie Mao, Yunan Wu, Peiyuan Zhuo, Yinzheng Zhang, Weilin Liu, Jia Huang, Jing Tao, Li‑Dian Chen
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Electroacupuncture inhibits inflammatory injury by targeting the miR‑9‑mediated NF‑κB signaling pathway following ischemic stroke

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Genistein inhibits the proliferation of human multiple myeloma cells through suppression of nuclear factor‑κB and upregulation of microRNA‑29b

Jie Xie, Jianchao Wang, Bo Zhu
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Expression profiles of heat shock protein 27 and αB-crystallin and their effects on heat-stressed rat myocardial cells in vitro and in vivo

Shu Tang, Hongbo Chen, Yanfen Cheng, Mohammad Abdel Nasir, Nicole Kemper, Endong Bao
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Downregulation of non‑muscle myosin IIA expression inhibits migration and invasion of gastric cancer cells via the c‑Jun N‑terminal kinase signaling pathway

Tao Liu, Yanwei Ye, Xiefu Zhang, Ali Zhu, Zhen Yang, Yang Fu, Chongqing Wei, Qi Liu, Chunlin Zhao, Guojun Wang
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Protein inhibitor of activated STAT xα depresses cyclin D and cyclin D kinase, and contributes to the inhibition of osteosarcoma cell progression

Junjie Wang, Jiangdong Ni, Shuai Yi, Deye Song, Muliang Ding
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Analysis of somatic mutations in braf, CDKN2A/p16 and PI3KCA in patients with medullary thyroid carcinoma

Fabrício P. Nascimento, Mirian G. Cardoso, Susan C. Lindsey, Ilda S. Kunii, Flávia O.F. Valente, Marina M.L. Kizys, Rosana Delcelo, Cléber P. Camacho, Rui M.B. Maciel, Magnus R. Dias‑Da‑Silva
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Nano-microcapsule basic fibroblast growth factor combined with hypoxia-inducible factor-1 improves random skin flap survival in rats

Guang‑Jun Chen, Yi‑Heng Chen, Xia‑Qing Yang, Zhi‑Jie Li
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Expression of surfactant protein-A in exhaled breath condensate of patients with chronic obstructive pulmonary disease

Xue‑Feng Lin, Lei Zhang, Shu‑Yuan Shi, Yi‑Chu Fan, Zhen‑Lin Wu, Xun Zhang, Da‑Qiang Sun
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Interleukin-17 potently increases non-small cell lung cancer growth

Lei Wei, Hui Wang, Fen Yang, Qi Ding, Jianhua Zhao
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SET8 induces epithelial‑mesenchymal transition and enhances prostate cancer cell metastasis by cooperating with ZEB1

Liejun Hou, Qiang Li, Yiming Yu, Ming Li, Dayong Zhang
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Resveratrol induces apoptosis through modulation of the Akt/FoxO3a/Bim pathway in HepG2 cells

Mi‑Hua Liu, Xiao‑Long Lin, Jian Li, Jun He, Tian‑Ping Tan, Shao‑Jian Wu, Shan Yu, Li Chen, Jun Liu, Wei Tian, Yu‑Dan Chen, Hong‑Yun Fu, Cong Yuan, Yuan Zhang
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Anti-inflammatory activity of Kochia scoparia fruit on contact dermatitis in mice

Suzy Jo, Junghyun Ryu, Hye‑Yeon Han, Geumsan Lee, Mi Heon Ryu, Hyungwoo Kim
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Anti‑diabetic activities of Paecilomyces tenuipes N45 extract in alloxan‑induced diabetic mice

Linna Du, Chungang Liu, Meiyu Teng, Qingfan Meng, Jiahui Lu, Yulin Zhou, Yan Liu, Yingkun Cheng, Di Wang, Lesheng Teng
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Oxidized low‑density lipoprotein upregulates microRNA‑146a via JNK and NF‑κB signaling

Zhenwei Li, Shuai Wang, Wenting Zhao, Zewei Sun, Hui Yan, Jianhua Zhu
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Curcumin upregulates Nrf2 nuclear translocation and protects rat hepatic stellate cells against oxidative stress

Zhenxiong Liu, Weijia Dou, Yuanyuan Zheng, Qinsheng Wen, Ming Qin, Xuxia Wang, Hua Tang, Rong Zhang, Dandan Lv, Jingjie Wang, Shuguang Zhao
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Myricetin inhibits Kv1.5 channels in HEK293 cells

Xianhong Ou, Xiaohong Bin, Luzhen Wang, Miaoling Li, Yan Yang, Xinrong Fan, Xiaorong Zeng
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MicroRNA‑200a mediates nasopharyngeal carcinoma cell proliferation through the activation of nuclear factor‑κB

Zhuliang Shi, Zhiqiang Hu, Delu Chen, Jie Huang, Jie Fan, Subo Zhou, Xin Wang, Jiandao Hu, Fei Huang
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Imatinib promotes apoptosis of giant cell tumor cells by targeting microRNA-30a-mediated runt‑related transcription factor 2

Yuxiang Liao, Guohua Lv, Bing Wang, Lei Kuang, Xiaobin Wang
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Differential gene expression analysis and network construction of recurrent cardiovascular events

Jiangquan Liao, Zhong Chen, Qinghong He, Yongmei Liu, Jie Wang
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Ting Xiao, Jian Luo, Zhixiong Wu, Fang Li, Ou Zeng, Jun Yang
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Increased expression of mitochondrial DNA‑encoded genes in human renal mesangial cells in response to high glucose‑induced reactive oxygen species

Ghada Al‑Kafaji, Mohamed Abdalla Sabry, Moiz Bakhiet
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Xin Zhang, Chao Ma, Qingjie Wang, Jia Liu, Mingyi Tian, Yuchang Yuan, Xingang Li, Xun Qu
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Isolation and comparison of mesenchymal stem cell‑like cells derived from human gastric cancer tissues and corresponding ovarian metastases

Kunyan Zhou, Man Xia, Bo Tang, Darong Yang, Nianli Liu, Dihong Tang, Hailong Xie, Xiaohong Wang, Haizhen Zhu, Chen Liu, Chaohui Zuo
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Effect of bone marrow-derived stem cells on chondrocytes from patients with osteoarthritis

Qiangzhi Zhang, Yong Chen, Qiang Wang, Chaoyong Fang, Yu Sun, Tao Yuan, Yuebei Wang, Rongni Bao, Ningjian Zhao
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Hypoxia induces the proliferation of endothelial progenitor cells via upregulation of Apelin/APLNR/MAPK signaling

Jingchang Zhang, Qiming Liu, Zhenfei Fang, Xinqun Hu, Feng Huang, Liang Tang, Shenghua Zhou
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Activation of Toll‑like receptor 7 regulates the expression of IFN‑λ1, p53, PTEN, VEGF, TIMP‑1 and MMP‑9 in pancreatic cancer cells

Fang Wang, Rui Jin, Bing‑Bing Zou, Lei Li, Feng‑Wei Cheng, Xin Luo, Xiaoping Geng, Sheng‑Quan Zhang
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Proteomic analysis reveals energy metabolic dysfunction and neurogenesis in the prefrontal cortex of a lipopolysaccharide‑induced mouse model of depression

Ziye Wang, Wenwen Li, Jin Chen, Haiyang Shi, Mingjun Zhao, Hongmin You, Chenglong Rao, Yuan Zhan, Yongtao Yang, Peng Xie
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Effects of RNA interference-mediated knockdown of livin and survivin using monomethoxypolyethylene glycol-chitosan nanoparticles in MG-63 osteosarcoma cells

Hua‑Peng Guan, Jian‑Zhong Sun, Xiao‑Lei Feng, Jin‑Shui Chen, Fang‑Jing Chen, Xiao‑Fei Cheng, Xin‑Wei Liu, Bin Ni
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Andrographolide inhibits multiple myeloma cells by inhibiting the TLR4/NF-κB signaling pathway

Hui Gao, Jianrong Wang
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Resveratrol protects mice from paraquat-induced lung injury: The important role of SIRT1 and NRF2 antioxidant pathways

Shengqin Li, Guangju Zhao, Longwang Chen, Yinwei Ding, Jie Lian, Guangliang Hong, Zhongqiu Lu
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Protective effects of black tea extract against oxidative DNA damage in human lymphocytes

Miriam Ježovičová, Katarína Koňariková, Zdeňka Ďuračková, Ján Keresteš, Gabriel Králik, Ingrid Žitňanová
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Downregulation of fatty acid synthase complex suppresses cell migration by targeting phospho‑AKT in bladder cancer

Shuai‑Shuai Zheng, Jian‑Gang Gao, Zhi‑Jun Liu, Xin‑Hong Zhang, Shuai Wu, Bo‑Wen Weng, You‑Lin Wang, Si‑Chuan Hou, Bo Jiang
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Article

Inhibition of E-cadherin/catenin complex formation by O-linked N-acetylglucosamine transferase is partially independent of its catalytic activity

Haiyan Liu, Yuchao Gu, Jieqiong Qi, Cuifang Han, Xinling Zhang, Chuanlin Bi, Wengong Yu
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Investigations on the antifatigue and antihypoxic effects of Paecilomyces hepiali extract

Juan Wang, Lan Zhou Li, Yan Ge Liu, Li Rong Teng, Jia Hui Lu, Jing Xie, Wen Ji Hu, Yan Liu, Yang Liu, Di Wang, Le Sheng Teng
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Survivin activates NF‑κB p65 via the IKKβ promoter in esophageal squamous cell carcinoma

Wei Zeng, Hui Li, Yan Chen, Hongbo Lv, Ling Liu, Jihua Ran, Xiaohong Sun, Shayahati Bieerkehazhi, Yining Liu, Xiaomiao Li, Wenting Lai, Jibieke Watibieke, Meiliwuerti Dawulietihan, Xiumei Li, Huiwu Li
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Expression profiles of inhibitor of growth protein 2 in normal and cancer tissues: An immunohistochemical screening analysis

Shuang Zhao, Xue‑Feng Yang, Wen‑Feng Gou, Hang Lu, Hua Li, Zhi‑Tu Zhu, Hong‑Zhi Sun, Hua‑Chuan Zheng
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Downregulation of connective tissue growth factor reduces migration and invasiveness of osteosarcoma cells

Yinjun Huang, Shichang Zhao, Changqing Zhang, Xiaolin Li
Pages: 1888-1894
Published online on: 22 December 2015

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Article

MicroRNA-20b-5p functions as a tumor suppressor in renal cell carcinoma by regulating cellular proliferation, migration and apoptosis

Yifan Li, Duqun Chen, Lu Jin, Jiaju Liu, Zhengming Su, Yuchi Li, Yaoting Gui, Yongqing Lai
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Published online on: 17 December 2015

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Identification of miR‑130b as an oncogene in renal cell carcinoma

Yifan Li, Duqun Chen, Yuchi Li, Lu Jin, Jiaju Liu, Zhengming Su, Zhengyu Qi, Min Shi, Zhimao Jiang, Yaoting Gui, Shangqi Yang, Xiangming Mao, Yongqing Lai
Pages: 1902-1908
Published online on: 30 December 2015

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Article

Type II cGMP-dependent protein kinase directly inhibits HER2 activation of gastric cancer cells

Miaolin Zhu, Xiaoyuan Yao, Min Wu, Hai Qian, Yan Wu, Yongchang Chen
Pages: 1909-1913
Published online on: 17 December 2015

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Intrathecal injection of phosphodiesterase 4B-specific siRNA attenuates neuropathic pain in rats with L5 spinal nerve ligation

Qing Ji, Yan Di, Xiaoyun He, Qingzhen Liu, Jian Liu, Weiyan Li, Lidong Zhang
Pages: 1914-1922
Published online on: 23 December 2015

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MicroRNA-101 sensitizes hepatocellular carcinoma cells to doxorubicin-induced apoptosis via targeting Mcl-1

Haifei He, Wei Tian, Hailong Chen, Yongchuan Deng
Pages: 1923-1929
Published online on: 28 December 2015

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Knockdown of PREX2a inhibits the malignant phenotype of osteosarcoma cells Retraction in /10.3892/mmr.2022.12630

Zixun Dai, Jie Xie, Pengfei Lei, Yihe Hu
Pages: 1930-1936
Published online on: 28 December 2015

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Xiaona Wang, Hua Du, Yingxu Shi
Article Number: 264
Published online on: 28 July 2026

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Review Open Access

Association between periodontitis and heart failure: Mechanisms and clinical implications (Review)

Xinyue Zhang, Xiaoli An
Article Number: 263
Published online on: 28 July 2026

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Article Open Access

Ginsenosides alleviate the progression of hepatic fibrosis by targeting the liver circadian clock gene CLOCK

Jiawen Yu, Chunmei Qian, Renye Que, Yi Zhou
Article Number: 262
Published online on: 28 July 2026

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Retraction Open Access

[Retracted] PPM1A as a key target of the application of Jiawei‑Maxing‑Shigan decoction for the attenuation of radiation‑induced epithelial‑mesenchymal transition in type II alveolar epithelial cells

Jinhua Lu, Shengyou Lin, Zechen Lin, Xianlei Lin, Yuezhong Shen, Jingyang Su
Article Number: 261
Published online on: 27 July 2026

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Article Open Access

UBE2A as a prognostic indicator across human cancers: Insights from multi‑omics and immune landscape analyses

Yun Wen, Pengfei Luo
Article Number: 260
Published online on: 23 July 2026

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November-2026 Volume 34 Issue 5

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Journal Metrics

Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Artemisinin and its derivatives for metabolic syndrome: From multi‑target mechanisms to translational opportunities (Review)

Shuo Cao, Mo Yang, Siyu Qu, Jinsong Wu, Jiaheng Li, Ying Zhao
Article Number: 315
Published online on: 17 September 2026

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Demethylase FTO attenuates atherosclerotic plaque via upregulating ABCA1 and ABCG1 expression by targeting ATG5

Fengxia Guo, Mei He, Yaonan Li, Kangning Zhu, Bing Hu
Article Number: 314
Published online on: 16 September 2026

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Correction Open Access

[Corrigendum] Bcl11b regulates enamel matrix protein expression and dental epithelial cell differentiation during rat tooth development

Ziyue Li, Guoqing Chen, Yaling Yang, Weihua Guo, Weidong Tian
Article Number: 313
Published online on: 16 September 2026

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Review Open Access

Integrin αVβ3 as a context‑dependent regulator of bone homeostasis: Insights into osteoporosis pathogenesis and therapeutic targeting (Review)

Changshun Chen, Xingxi Hu, Sixing Wei, Yongcheng Deng, Qinggang Zhao, Ge Chen, Zhong Cheng, Jianhua Ji, Jinyi Gu
Article Number: 312
Published online on: 15 September 2026

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Therapeutic effects of exosome‑based hyperin delivery in a cyclophosphamide‑induced mouse model of diminished ovarian reserve

Yi Ying, Yue Wu, Ji Zhou, Yaming Wang, Hongtao Yin, Gang Lu, Ruolang Pan, Liangzhong Lv
Article Number: 311
Published online on: 15 September 2026

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Review Open Access

Arginine metabolism, polyamine homeostasis and ferroptosis in cancer: Molecular links and therapeutic opportunities (Review)

Xin Dong, Yongkun Hou, Jingjing Shao, Haixia Zhu, Jibin Liu
Article Number: 310
Published online on: 15 September 2026

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Mitochondria‑associated endoplasmic reticulum membranes in degenerative musculoskeletal disorders: Mechanistic evidence and therapeutic perspectives (Review)

Shilong Meng, Xinlei Fu, Yawei Xu, Zhiliang Peng, Xu Zhang, Yanguang Cao, Binbin Tang, Xiaolin Shi, Kang Liu
Article Number: 309
Published online on: 15 September 2026

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High‑fat diet exacerbates hepatic and adipose insulin signaling impairment and ovarian lesions in a rat model of letrozole‑induced polycystic ovary syndrome

Sunju So, Sujin Kwon, La Yoon Choi, Dae Yong Kim, Mi Hye Kim
Article Number: 308
Published online on: 15 September 2026

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Retraction Open Access

[Retracted] RNAi‑mediated A disintegrin and metalloproteinase 9 gene silencing inhibits the tumor growth of non‑small lung cancer in vitro and in vivo

Liang Chang, Fangchao Gong, Youbin Cui
Article Number: 307
Published online on: 14 September 2026

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A four‑gene signature identifies TKI‑induced persister cells and uncovers a ZLN005‑induced pyroptotic vulnerability via the GSDME pathway in EGFR‑mutant lung cancer

Wenwen Chang, Jiaxin Yuan, Huilin Zhang, Ying Yu, Yan Ma, Mingyue Li, Wenjing Li, Hongxia Yan, Chongran Sun, Peng Zhang, Yang Tian, Feng Guo, Pan Li, Yang Sun
Article Number: 306
Published online on: 11 September 2026

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Research advances in the microbiota‑gut‑brain axis and Parkinson's disease (Review)

Yangping Meng, Qian Liu, Hao Zou, Xingyu Zhu, Xinxin Mi, Sitong Li, Yutian Xia, Yucheng Ma, Qianyu Yang, Jiaxin Peng, Junrui Li, Xingliang Liu, Junli Chen
Article Number: 305
Published online on: 10 September 2026

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Article Open Access

Ameliorative effects of Paulownia tomentosa flower absolute on atopic dermatitis‑related responses in mast cells and keratinocytes and its chemical composition

Da Yeon Yoo, Kyung Jong Won, Do Yoon Kim, Yoon Yi Kim, Ji Hye Bae, Ji Seong Yun, Hwan Myung Lee
Article Number: 304
Published online on: 10 September 2026

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Retraction Open Access

[Retracted] PYGB siRNA inhibits the cell proliferation of human osteosarcoma cell lines

Shuwei Zhang, Yichi Zhou, Yuanyu Zha, Yang Yang, Linlong Wang, Jingfeng Li, Wei Jin
Article Number: 303
Published online on: 10 September 2026

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Article Open Access

KIF4A drives esophageal squamous cell carcinoma via Wnt/β‑catenin signaling and predicts poor prognosis

Jialong Chen, Tong Wang, Da Wang, Weiguo Liu, Chunlai Liu, Yang Yang, Xiangfu Sun, Lei Zhou
Article Number: 302
Published online on: 08 September 2026

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Review Open Access

Research progress of aptamers in the diagnosis and treatment of colorectal cancer (Review)

Yiwen Li, Penghui Yan, Ji Zhang, Binghui Wu, Min Li, Baoliang Bao
Article Number: 301
Published online on: 08 September 2026

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Review Open Access

Role of the circadian rhythm in squamous cell carcinoma: From molecular mechanism to therapy (Review)

Mary-Lyn Eichhorn, Anna M. Dmitrieva, Lydia Meder
Article Number: 300
Published online on: 08 September 2026

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Expression of Concern Open Access

[Expression of Concern] Ganoderma lucidum polysaccharide inhibits prostate cancer cell migration via the protein arginine methyltransferase 6 signaling pathway

Xiaohui Zhao, Dayu Zhou, Yunen Liu, Chun Li, Xiaoguang Zhao, Ying Li, Wei Li
Article Number: 299
Published online on: 07 September 2026

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Review Open Access

Multi‑omics approaches to decipher the molecular mechanisms of exercise‑mediated bone protection: From mechanistic insights to personalized exercise prescription (Review)

Bin Tian, Xuesong Chen, Xin Kang
Article Number: 298
Published online on: 03 September 2026

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Retraction Open Access

[Retracted] MicroRNA‑27a promotes tumorigenesis via targeting AKT in triple negative breast cancer

Jing Wu, Zhihui Sun, Huijie Sun, Yanhua Li
Article Number: 297
Published online on: 03 September 2026

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