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Molecular Medicine Reports
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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
September-2016 Volume 14 Issue 3

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review

Potential use of visible and near-infrared spectroscopy for the analysis and diagnosis of chronic fatigue syndrome (Review)

Akikazu Sakudo
Pages: 1875-1879
Published online on: 07 July 2016

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Article Open Access

Evaluation of urinary bladder fibrogenesis in a mouse model of long-term ketamine injection

Cheng‑Huang Shen, Shou‑Chieh Wang, Shou‑Tsung Wang, Shu‑Mei Lin, Jiann‑Der Wu, Chang‑Te Lin, Yi‑Wen Liu
Pages: 1880-1890
Published online on: 07 July 2016

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Article Open Access

Disruption of kif3a results in defective osteoblastic differentiation in dental mesenchymal stem/precursor cells via the Wnt signaling pathway

Sicong Jiang, Guoqing Chen, Lian Feng, Zongting Jiang, Mei Yu, Jinku Bao, Weidong Tian
Pages: 1891-1900
Published online on: 12 July 2016

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Article Open Access

Slit2‑Robo1 signaling promotes the adhesion, invasion and migration of tongue carcinoma cells via upregulating matrix metalloproteinases 2 and 9, and downregulating E‑cadherin

Yuan Zhao, Feng-Li Zhou, Wei‑Ping Li, Jing Wang, Li‑Jing Wang
Pages: 1901-1906
Published online on: 13 July 2016

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Article Open Access

Bufalin suppresses cancer stem-like cells in gemcitabine-resistant pancreatic cancer cells via Hedgehog signaling

Haiyong Wang, Zhouyu Ning, Yingyi Li, Xiaoyan Zhu, Zhiqiang Meng
Pages: 1907-1914
Published online on: 06 July 2016

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Article Open Access

Caveolin-1 is critical in the proliferative effect of leptin on osteoblasts through the activation of Akt

Lin Zou, Guichun Zhang, Lifeng Liu, Chen Chen, Xuecheng Cao, Jinfang Cai
Pages: 1915-1922
Published online on: 01 July 2016

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Article Open Access

The effect of LOXL2 in hepatocellular carcinoma

Linghong Wu, Yuan Zhang, Ying Zhu, Qingwei Cong, Yan Xiang, Linlin Fu
Pages: 1923-1932
Published online on: 06 July 2016

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Article Open Access

Expression and clinical significance of Apollon in esophageal squamous cell carcinoma

Rong Li, Bo‑Lin Chen, Yan‑Wu Zhou, Ren‑Wei Guo, Meng‑Ting Shuai, Jun‑Xian Zeng, Ai‑Min Leng
Pages: 1933-1940
Published online on: 06 July 2016

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Article Open Access

Molecular analysis of FGFR 2 and associated clinical observations in two Chinese families with Crouzon syndrome

Ying Lin, Hongbin Gao, Siming Ai, Jacob V.P. Eswarakumar, Tao Li, Bingqian Liu, Hongye Jiang, Yuhua Liu, Xialin Liu, Yonghao Li, Yao Ni, Jiangna Chen, Zhuoling Lin, Xiaoling Liang, Chenjin Jin, Xinhua Huang, Lin Lu, Yizhi Liu
Pages: 1941-1946
Published online on: 11 July 2016

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Article Open Access

HIV‑1 downregulates the expression and phosphorylation of receptor tyrosine kinase by targeting the NF‑κB pathway

Tingting Feng, Jianhe Gan, Ailan Qin, Xiaoping Huang, Nanping Wu, Hua Hu, Hangping Yao
Pages: 1947-1952
Published online on: 08 July 2016

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Article Open Access

mRNA expression of TLR4, TLR9 and NF-κB in a neonatal murine model of necrotizing enterocolitis

Yiyu Yin, Fengli Liu, Yiping Li, Ruze Tang, Jian Wang
Pages: 1953-1956
Published online on: 29 June 2016

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Article Open Access

Aspirin inhibits osteoclastogenesis by suppressing the activation of NF-κB and MAPKs in RANKL-induced RAW264.7 cells

Yan‑Ping Zeng, Chao Yang, Yuan Li, Yong Fan, Hong‑Jun Yang, Bin Liu, Hong‑Xun Sang
Pages: 1957-1962
Published online on: 30 June 2016

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Article Open Access

Antioxidant effect of angiotensin (1‑7) in the protection of pancreatic β cell function

Fen Zhang, Chang Liu, Lei Wang, Xi Cao, Ying Ying Wang, Jin Kui Yang
Pages: 1963-1969
Published online on: 13 July 2016

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Article Open Access

A novel manganese complex selectively induces malignant glioma cell death by targeting mitochondria

Ji Geng, Jing Li, Tao Huang, Kaidi Zhao, Qiuyun Chen, Wenjie Guo, Jing Gao
Pages: 1970-1978
Published online on: 12 July 2016

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Article Open Access

Endothelial lipase is upregulated by interleukin-6 partly via the p38 MAPK and p65 NF-κB signaling pathways

Xin Yue, Minghui Wu, Hong Jiang, Jing Hao, Qinghao Zhao, Qing Zhu, Gaowa Saren, Yun Zhang, Xiaoli Zhang
Pages: 1979-1985
Published online on: 30 June 2016

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Article Open Access

Luteolin decreases the UVA‑induced autophagy of human skin fibroblasts by scavenging ROS

Miaomiao Yan, Zhongrong Liu, Huilan Yang, Cuihua Li, Hulin Chen, Yan Liu, Minling Zhao, Yingjie Zhu
Pages: 1986-1992
Published online on: 13 July 2016

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Article Open Access

Directed differentiation of postnatal hippocampal neural stem cells generates nuclear receptor related‑1 protein‑ and tyrosine hydroxylase‑expressing cells

Yinxiu Ding, Zixin Zhang, Jiangbo Ma, Hechun Xia, Yin Wang, Yinming Liu, Quanrui Ma, Tao Sun, Juan Liu
Pages: 1993-1999
Published online on: 08 July 2016

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Article Open Access

Investigation of the anti‑asthmatic activity of Oridonin on a mouse model of asthma

Jing Wang, Fengsen Li, Jianbing Ding, Ge Tian, Min Jiang, Zhen Gao, Ehbal Tuyghun
Pages: 2000-2006
Published online on: 08 July 2016

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Article Open Access

Protection of rat liver against hepatic ischemia-reperfusion injury by a novel selenocysteine-containing 7-mer peptide

Qianqian Jiang, Yu Pan, Yupeng Cheng, Huiling Li, Hui Li
Pages: 2007-2015
Published online on: 01 July 2016

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Article Open Access

Inhibitor of DNA binding 1 regulates cell cycle progression of endothelial progenitor cells through induction of Wnt2 expression

Xi Xia, Yang Yu, Li Zhang, Yang Ma, Hong Wang
Pages: 2016-2024
Published online on: 08 July 2016

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Article Open Access

Effects of imatinib and nilotinib on the whole transcriptome of cultured murine osteoblasts

Gyöngyi Kirschner, Bernadett Balla, Péter Horváth, Andrea Kövesdi, Gergely Lakatos, István Takács, Zsolt Nagy, Bálint Tóbiás, Kristóf Árvai, János Pál Kósa, Péter Lakatos
Pages: 2025-2037
Published online on: 30 June 2016

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Article Open Access

The expression pattern of Adam10 in the central nervous system of adult mice: Detection by in situ hybridization combined with immunohistochemistry staining

Zhi‑Bao Guo, Ying‑Ying Su, Yi‑Hui Wang, Wei Wang, Da‑Zhi Guo
Pages: 2038-2044
Published online on: 11 July 2016

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Article Open Access

Dynamic co-expression network analysis of lncRNAs and mRNAs associated with venous congestion

Jinshun Li, Yuqin Xu, Jia Xu, Jinhua Wang, Liying Wu
Pages: 2045-2051
Published online on: 07 July 2016

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Article Open Access

Role of platelet function and platelet membrane glycoproteins in children with primary immune thrombocytopenia

Wen-Jun Liu, Jing Bai, Qu-Lian Guo, Zhe Huang, Hong Yang, Yong-Qi Bai
Pages: 2052-2060
Published online on: 11 July 2016

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Article

A novel in-frame deletion in MEN1 (p.Ala416del) causes familial multiple endocrine neoplasia type 1 with an aggressive phenotype and unexpected inheritance pattern

Anna Skalniak, Grzegorz Sokołowski, Agata Jabrocka‑Hybel, Jakub Piątkowski, Magdalena Białas, Aleksandra Gilis‑Januszewska, Dorota Pach, Alicja Hubalewska‑Dydejczyk
Pages: 2061-2066
Published online on: 01 July 2016

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Article

Differential long non‑coding RNA and mRNA expression in differentiated human glioblastoma stem cells

Hao Li, Haowen Li, Yajing Hao, Yuming Jiao, Zhicen Li, Haiyan Yue, Zhe Xu, Shuo Wang, Yong Cao, Jizong Zhao
Pages: 2067-2076
Published online on: 12 July 2016

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Article

miRNA-30a functions as a tumor suppressor by downregulating cyclin E2 expression in castration-resistant prostate cancer

Lei Zhang, Xiao‑Wen Zhang, Chun‑Hui Liu, Kai Lu, Ye‑Qing Huang, Yi‑Duo Wang, Li Xing, Li‑Jie Zhang, Ning Liu, Hua Jiang, Chao Sun, Yu Yang, Shu‑Qiu Chen, Ming Chen, Bin Xu
Pages: 2077-2084
Published online on: 06 July 2016

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Article

Effects of microRNA‑338‑3p on morphine‑induced apoptosis and its underlying mechanisms

Hong‑Liang Weng, Ming‑Jing Wang
Pages: 2085-2092
Published online on: 12 July 2016

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Article

Dynamic metabolic profiling of urine biomarkers in rats with alcohol‑induced liver damage following treatment with Zhi‑Zi‑Da‑Huang decoction

Li An, Qiaoling Lang, Wenbin Shen, Qingshui Shi, Fang Feng
Pages: 2093-2100
Published online on: 11 July 2016

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Article

Enhanced expression levels of aquaporin-1 and aquaporin-4 in A549 cells exposed to silicon dioxide

Xiaohui Hao, Hongli Wang, Wei Liu, Shupeng Liu, Zihe Peng, Yue Sun, Jinyuan Zhao, Qiujie Jiang, Heliang Liu
Pages: 2101-2106
Published online on: 07 July 2016

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Article

Targeted next-generation sequencing identification of a novel missense mutation of the SKIV2L gene in a patient with trichohepatoenteric syndrome

Bixia Zheng, Jian Pan, Yu Jin, Chunli Wang, Zhifeng Liu
Pages: 2107-2110
Published online on: 11 July 2016

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Article

Silencing of osterix expression by siRNA inhibits aldosterone‑induced calcification of vascular smooth muscle cells in mice

Yan‑Chun Gong, Yue He, Hao Wang, Wen‑Quan Niu, Kai‑Da Ji, Hua Li
Pages: 2111-2118
Published online on: 08 July 2016

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Article

Sevoflurane inhibits the self-renewal of mouse embryonic stem cells via the GABAAR-ERK signaling pathway

Liuqing Yang, Yali Ge, Shunyan Lin, Xiangzhi Fang, Loujing Zhou, Ju Gao
Pages: 2119-2126
Published online on: 04 July 2016

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Article

microRNA-7 regulates cell growth, migration and invasion via direct targeting of PAK1 in thyroid cancer Retraction in /10.3892/mmr.2023.12992

Kai Yue, Xudong Wang, Yansheng Wu, Xuan Zhou, Qinghua He, Yuansheng Duan
Pages: 2127-2134
Published online on: 07 July 2016

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Article

B7-H4 expression in human infiltrating ductal carcinoma‑associated macrophages

Lei Liu, Dalin Li, Shuang Chen, Ran Zhao, Da Pang, Dianjun Li, Zhenkun Fu
Pages: 2135-2142
Published online on: 13 July 2016

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Article

Paeoniflorin inhibits proliferation and promotes apoptosis of multiple myeloma cells via its effects on microRNA‑29b and matrix metalloproteinase‑2

Shaofeng Wang, Wenhua Liu
Pages: 2143-2149
Published online on: 11 July 2016

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Article

Identification of a novel frameshift heterozygous deletion in exon 8 of the PAX6 gene in a pedigree with aniridia

Ozlem Giray Bozkaya, Esra Ataman, Ozge Aksel Kilicarslan, Tufan Cankaya, Ayfer Ulgenalp
Pages: 2150-2154
Published online on: 05 July 2016

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Article

The anti‑dengue virus properties of statins may be associated with alterations in the cellular antiviral profile expression

Owen Lloyd Bryan‑Marrugo, Daniel Arellanos-Soto, Augusto Rojas‑Martinez, Hugo Barrera‑Saldaña, Javier Ramos‑Jimenez, Roman Vidaltamayo, Ana María Rivas‑Estilla
Pages: 2155-2163
Published online on: 13 July 2016

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Article

Upregulation of kallikrein‑related peptidase 5 is associated with the malignant behavior of colorectal cancer

Yanhua Wu, Yingjian Chen, Qing Li, Yanwen Gong, Xiaohong Liu, Liquan Bi, Chengjin Hu
Pages: 2164-2170
Published online on: 13 July 2016

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Article

Suppression of tumor cell proliferation by quinine via the inhibition of the tumor necrosis factor receptor‑associated factor 6‑AKT interaction

Wenjuan Liu, Yonghao Qi, Lingyu Liu, Yu Tang, Jing Wei, Lijun Zhou
Pages: 2171-2179
Published online on: 11 July 2016

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Article

Identification of two novel mutations in the COMP gene in six families with pseudoachondroplasia

Wei‑Jia Yu, Zeng Zhang, Jin‑Wei He, Wen‑Zhen Fu, Chun Wang, Zhen‑Lin Zhang
Pages: 2180-2186
Published online on: 08 July 2016

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Article

Effects of irreversible electroporation on cervical cancer cell lines in vitro

Qin Qin, Zheng‑Ai Xiong, Ying Liu, Chen‑Guo Yao, Wei Zhou, Yuan‑Yuan Hua, Zhi‑Liang Wang
Pages: 2187-2193
Published online on: 05 July 2016

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Article

Anti‑migratory effect of rapamycin impairs allograft imaging by 18F‑fluorodeoxyglucose‑labeled splenocytes

Hukui Sun, Dayan Cheng, Yuanyuan Ma, Hong Liu, Ning Yang, Cong Zhang, Kai Wang, Guihua Hou, Huaiquan Wang
Pages: 2194-2198
Published online on: 12 July 2016

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Article

Quantitative PCR marker genes for endometrial adenocarcinoma

Alexandra C. Kölbl, Lisa‑Marie Victor, Amelie E. Birk, Udo Jeschke, Ulrich Andergassen
Pages: 2199-2205
Published online on: 07 July 2016

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Article

Alteration of the immune status of umbilical cord mesenchymal stem cells stimulated by TLR1/2 agonist, Pam3Csk

Pingxi Wang, Fanwei Zeng, Lina He, Jin Wang, Tingjiu Zhang, Dong Zhang
Pages: 2206-2212
Published online on: 13 July 2016

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Article

Confirming an integrated pathology of diabetes and its complications by molecular biomarker-target network analysis

Zide Zhao, Yingying Zhang, Fengchun Gai, Ying Wang
Pages: 2213-2221
Published online on: 07 July 2016

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Article

Inhibition of multiple myeloma cell proliferation by ginsenoside Rg3 via reduction in the secretion of IGF-1

Yan Li, Tao Yang, Jing Li, Hong‑Ling Hao, Su‑Yun Wang, Jie Yang, Jian‑Min Luo
Pages: 2222-2230
Published online on: 07 July 2016

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Article

Increased protein expression levels of pCREB, BDNF and SDF-1/CXCR4 in the hippocampus may be associated with enhanced neurogenesis induced by environmental enrichment

Xiao Qian Zhang, Jing Wei Mu, Hui Bin Wang, Jukka Jolkkonen, Ting Ting Liu, Ting Xiao, Mei Zhao, Chao Dong Zhang, Chuan Sheng Zhao
Pages: 2231-2237
Published online on: 06 July 2016

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Article

Aberrant expression of anaplastic lymphoma kinase in lung adenocarcinoma: Analysis of circulating free tumor RNA using one-step reverse transcription-polymerase chain reaction

Rossella Bruno, Mirella Giordano, Riccardo Giannini, Greta Alì, Gianfranco Puppo, Alessandro Ribechini, Antonio Chella, Gabriella Fontanini
Pages: 2238-2242
Published online on: 07 July 2016

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Article

Differential proteomics of the synovial membrane between bilateral and unilateral knee osteoarthritis in surgery‑induced rabbit models

Weilin Liu, Jian He, Ruhui Lin, Jie Liang, Qinglu Luo
Pages: 2243-2249
Published online on: 13 July 2016

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Article

Berberine enhances the anti‑tumor activity of tamoxifen in drug‑sensitive MCF‑7 and drug‑resistant MCF‑7/TAM cells

Chunjie Wen, Lanxiang Wu, Lijuan Fu, Xue Zhang, Honghao Zhou
Pages: 2250-2256
Published online on: 08 July 2016

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Article

Functional expression of human α7 nicotinic acetylcholine receptor in human embryonic kidney 293 cells

Yuan Gong, Ji‑Hong Jiang, Shi‑Tong Li
Pages: 2257-2263
Published online on: 11 July 2016

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Article

Increased levels of circulating adrenomedullin following treatment with TU‑100 in patients with Crohn's disease

Ken Kominato, Hiroshi Yamasaki, Keiichi Mitsuyama, Hidetoshi Takedatsu, Shinichiro Yoshioka, Kotaro Kuwaki, Teppei Kobayashi, Ryosuke Yamauchi, Shuhei Fukunaga, Osamu Tsuruta, Takuji Torimura
Pages: 2264-2268
Published online on: 08 July 2016

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Article

Platelet‑rich plasma promotes the migration and invasion of synovial fibroblasts in patients with rheumatoid arthritis

Shanshan Yan, Binzhou Yang, Chen Shang, Zhongshuang Ma, Zizheng Tang, Guiping Liu, Weigan Shen, Yu Zhang
Pages: 2269-2275
Published online on: 11 July 2016

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Article

Association between methylenetetrahydrofolate reductase (MTHFR) polymorphisms and susceptibility to Graves' ophthalmopathy

Jae Yeun Lee, Nam Keun Kim, Yong Wook Cho, Helen Lew
Pages: 2276-2282
Published online on: 30 June 2016

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Article

Dickkopf 2 promotes proliferation and invasion via Wnt signaling in prostate cancer

Wei Xu, Kuan Pang, Ze‑Guang Zhou, Yi‑Feng Chen, Ting Mo, Ming Li, Cheng‑Bei Liu
Pages: 2283-2288
Published online on: 11 July 2016

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Article

Pioglitazone affects the OPG/RANKL/RANK system and increase osteoclastogenesis

Fei Xu, Yonghui Dong, Xin Huang, Peng Chen, Fengjing Guo, Anmin Chen, Shilong Huang
Pages: 2289-2296
Published online on: 13 July 2016

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Article

A single nucleotide polymorphism in hsa‑miR‑146a is responsible for the development of bronchial hyperresponsiveness in response to intubation during general anesthesia

Yong Luan, Dongjiang Li, Lulu Gao, Sha Xie, Ling Pei
Pages: 2297-2304
Published online on: 11 July 2016

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Article

rs78378222 polymorphism in the 3'-untranslated region of TP53 contributes to development of age-associated cataracts by modifying microRNA-125b-induced apoptosis of lens epithelial cells

Yang Zhao, Xiao Li, Siquan Zhu
Pages: 2305-2310
Published online on: 04 July 2016

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Article

microRNA-199a-3p functions as tumor suppressor by regulating glucose metabolism in testicular germ cell tumors

Xiaowen Liu, Hongyan Duan, Shihua Zhou, Zhiyong Liu, Daobing Wu, Ting Zhao, Shan Xu, Lifang Yang, Dan Li
Pages: 2311-2320
Published online on: 06 July 2016

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Article

Protective effect of cannabidiol on hydrogen peroxide‑induced apoptosis, inflammation and oxidative stress in nucleus pulposus cells

Jie Chen, Chen Hou, Xin Chen, Dong Wang, Pinglin Yang, Xijing He, Jinsong Zhou, Haopeng Li
Pages: 2321-2327
Published online on: 13 July 2016

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Article

miRNA polymorphisms (miR‑146a, miR‑149, miR‑196a2 and miR‑499) are associated with the risk of coronary artery disease

Jung‑Hoon Sung, Sang‑Hoon Kim, Woo‑In Yang, Won‑Jang Kim, Jae‑Youn Moon, In Jai Kim, Dong‑Hun Cha, Seung‑Yun Cho, Jung Oh Kim, Kyeong Ah Kim, Ok‑Joon Kim, Sang‑Wook Lim, Nam‑Keun Kim
Pages: 2328-2342
Published online on: 11 July 2016

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Article

Endostatin and irradiation modifies the activity of ADAM10 and neprilysin in breast cancer cells

Esra Arslan Aydemir, Ece Şimşek, Aylin Fidan Korcum, Kayahan Fişkin
Pages: 2343-2351
Published online on: 01 July 2016

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Article

Apigenin inhibits glioma cell growth through promoting microRNA-16 and suppression of BCL-2 and nuclear factor-κB/MMP‑9

Xin‑Jun Chen, Mian‑Yun Wu, Deng‑Hui Li, Jin You
Pages: 2352-2358
Published online on: 30 June 2016

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Article

Cytotoxic effects of NF‑κB inhibitors in combination with anti‑herpes agents on Epstein‑Barr virus‑positive gastric carcinoma in vitro

Paula Ordonez, Athira Nandakumar, Chihaya Koriyama, Megumi Yamomoto, Suminori Akiba
Pages: 2359-2367
Published online on: 11 July 2016

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Article

Emodin‑8‑O‑glucuronic acid, from the traditional Chinese medicine qinghuobaiduyin, affects the secretion of inflammatory cytokines in LPS‑stimulated raw 264.7 cells via HSP70

Ping Wang, Quanyong He, Jie Zhu
Pages: 2368-2372
Published online on: 13 July 2016

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Article Open Access

Application of network construction to estimate functional changes to insulin receptor substrates 1 and 2 in Huh7 cells following infection with the hepatitis C virus

Jingkun Liu, Linbang Wang, Wenjun Wang, Yaping Li, Xiaoli Jia, Song Zhai, Juan Shi, Shuangsuo Dang
Pages: 2379-2388
Published online on: 18 July 2016

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The protective role of vitamin D3 in a murine model of asthma via the suppression of TGF-β/Smad signaling and activation of the Nrf2/HO-1 pathway

Zhihui Wang, Haitao Zhang, Xiaohan Sun, Lihong Ren
Pages: 2389-2396
Published online on: 27 July 2016

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Therapeutic effects of paeonol on methyl-4-phenyl-1,2,3,6-tetrahydropyridine/probenecid-induced Parkinson's disease in mice

Xiaojin Shi, Yu‑Hua Chen, Hao Liu, Hong‑Dang Qu
Pages: 2397-2404
Published online on: 28 July 2016

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Article

Proteomic analysis of the effects of CSF-1 and IL-1α on dental follicle cells

Chanchan Chen, Nan Xie, Junqi Ling, Yu Du, Haijing Gu
Pages: 2405-2414
Published online on: 28 July 2016

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Article Open Access

Telocytes as potential targets in a cyclophosphamide-induced animal model of premature ovarian failure

Te Liu, Suwei Wang, Qiong Li, Yongyi Huang, Chuan Chen, Jin Zheng
Pages: 2415-2422
Published online on: 22 July 2016

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Trichostatin A increases the TIMP-1/MMP ratio to protect against osteoarthritis in an animal model of the disease

Hao Qu, Jin Li, Li‑Dong Wu, Wei‑Ping Chen
Pages: 2423-2430
Published online on: 18 July 2016

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Co-expression of ING4 and P53 enhances hypopharyngeal cancer chemosensitivity to cisplatin in vivo

Xin Ren, Hao Liu, Mingjie Zhang, Mengjun Wang, Shiyin Ma
Pages: 2431-2438
Published online on: 27 July 2016

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Article Open Access

Molecular analysis of myocilin and optineurin genes in Korean primary glaucoma patients

Joonhong Park, Myungshin Kim, Chan Kee Park, Hyojin Chae, Seungok Lee, Yonggoo Kim, Woori Jang, Hyun Young Chi, Hae‑Young Lopilly Park, Shin Hae Park
Pages: 2439-2448
Published online on: 27 July 2016

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Semaphorin 3A-modified adipose-derived stem cell sheet may improve osseointegration in a type 2 diabetes mellitus rat model

Kaixiu Fang, Wen Song, Lifeng Wang, Xiaoru Xu, Naiwen Tan, Sijia Zhang, Hongbo Wei, Yingliang Song
Pages: 2449-2456
Published online on: 28 July 2016

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Periodic mechanical stress induces the extracellular matrix expression and migration of rat nucleus pulposus cells by upregulating the expression of intergrin α1 and phosphorylation of downstream phospholipase Cγ1

Gongming Gao, Jin He, Luming Nong, Hua Xie, Yongjing Huang, Nanwei Xu, Dong Zhou
Pages: 2457-2464
Published online on: 27 July 2016

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Article Open Access

LncRNA HOTAIR controls the expression of Rab22a by sponging miR-373 in ovarian cancer Retraction in /10.3892/mmr.2024.13346

Zhongbao Zhang, Jiajing Cheng, Yi Wu, Jin Qiu, Yi Sun, Xiaowen Tong
Pages: 2465-2472
Published online on: 28 July 2016

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Article Open Access

Wnt3a is critical for endothelial progenitor cell-mediated neural stem cell proliferation and differentiation

Yibin Du, Shuo Zhang, Tao Yu, Gongwen Du, Hui Zhang, Zongsheng Yin
Pages: 2473-2482
Published online on: 01 August 2016

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Resistant mechanisms and molecular epidemiology of imipenem-resistant Acinetobacter baumannii

Shu‑Zhen Xiao, Hai‑Qing Chu, Li‑Zhong Han, Zhe‑Min Zhang, Bing Li, Lan Zhao, Liyun Xu
Pages: 2483-2488
Published online on: 22 July 2016

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Downregulation of thrombospondin-1 by DNA hypermethylation is associated with tumor progression in laryngeal squamous cell carcinoma

Chuang Huang, Xiaohong Zhou, Zhenhua Li, Hong Liu, Yun He, Guo Ye, Kun Huang
Pages: 2489-2496
Published online on: 01 August 2016

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Cerebral vasoconstriction reactions and plasma levels of ETBR, ET-1, and eNOS in patients with chronic high altitude disease

Shizheng Wu, Guisheng Hao, Shukun Zhang, Dongmei Jiang, Tana Wuren, Junming Luo
Pages: 2497-2502
Published online on: 27 July 2016

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MicroRNA-363 and GATA-1 are regulated by HIF-1α in K562 cells under hypoxia

Youbang Xie, Wenqian Li, Jianming Feng, Tianyi Wu, Jianping Li
Pages: 2503-2510
Published online on: 29 July 2016

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Effects of cisplatin on the LSD1-mediated invasion and metastasis of prostate cancer cells Retraction in /10.3892/mmr.2023.13027

Zhi‑Yuan Chen, Hui Chen, Tao Qiu, Xiao‑Dong Weng, Jia Guo, Lei Wang, Xiu‑Heng Liu
Pages: 2511-2517
Published online on: 28 July 2016

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Low-dose testosterone alleviates vascular damage caused by castration in male rats in puberty via modulation of the PI3K/AKT signaling pathway

Jing Zhao, Ge‑Li Liu, Ying Wei, Li‑Hong Jiang, Peng‑Li Bao, Qing‑Yan Yang
Pages: 2518-2526
Published online on: 27 July 2016

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Generation of porcine fetal fibroblasts expressing the tetracycline-inducible Cas9 gene by somatic cell nuclear transfer

Guoqian Liu, Kai Liu, Hengxi Wei, Li Li, Shouquan Zhang
Pages: 2527-2533
Published online on: 19 July 2016

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α-TEA inhibits the growth and motility of human colon cancer cells via targeting RhoA/ROCK signaling

Jialin Yao, Peng Gao, Yang Xu, Zhaozhu Li
Pages: 2534-2540
Published online on: 18 July 2016

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Loss of coxsackie and adenovirus receptor expression in human colorectal cancer: A potential impact on the efficacy of adenovirus-mediated gene therapy in Chinese Han population

Ying‑Yu Ma, Xiao‑Jun Wang, Yong Han, Gang Li, Hui‑Ju Wang, Shi‑Bing Wang, Xiao‑Yi Chen, Fan‑Long Liu, Xiang‑Lei He, Xiang‑Min Tong, Xiao‑Zhou Mou
Pages: 2541-2547
Published online on: 21 July 2016

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Co-expression of autophagic markers following photodynamic therapy in SW620 human colon adenocarcinoma cells

Barbara Ziółkowska, Marta Woźniak, Piotr Ziółkowski
Pages: 2548-2554
Published online on: 25 July 2016

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Analysis of different components in the peritumoral tissue microenvironment of colorectal cancer: A potential prospect in tumorigenesis Corrigendum in /10.3892/mmr.2016.5882

Chao Huang, Hong Liu, Xiuli Gong, Bin Wen, Dan Chen, Jinyuan Liu, Fengliang Hu
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Dysregulated function of normal human epidermal keratinocytes in the absence of filaggrin

Ningning Dang, Xiaoli Ma, Xianguang Meng, Liguo An, Shuguang Pang
Pages: 2566-2572
Published online on: 22 July 2016

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Rescued expression of WIF-1 in gallbladder cancer inhibits tumor growth and induces tumor cell apoptosis with altered expression of proteins

Yan Huang, Qiang Du, Weibao Wu, Feifei She, Yanling Chen
Pages: 2573-2581
Published online on: 19 July 2016

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Neuroprotection induced by post-conditioning following ischemia/reperfusion in mice is associated with altered microRNA expression

Wei Miao, Tian‑Hao Bao, Jian‑Hong Han, Mei Yin, Jie Zhang, Yong Yan, Yu‑Hong Zhu
Pages: 2582-2588
Published online on: 29 July 2016

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Zisheng Shenqi decoction ameliorates monosodium urate crystal-induced gouty arthritis in rats through anti-inflammatory and anti-oxidative effects

Jieru Han, Ying Xie, Fangyu Sui, Chunhong Liu, Xiaowei Du, Chenggang Liu, Xiaoling Feng, Deyou Jiang
Pages: 2589-2597
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Tumorigenic lung tumorospheres exhibit stem-like features with significantly increased expression of CD133 and ABCG2

Wensi Zhao, Yi Luo, Boyi Li, Tao Zhang
Pages: 2598-2606
Published online on: 18 July 2016

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Angiopoietin-like protein 2 expression is suppressed by angiotensin II via the angiotensin II type 1 receptor in rat cardiomyocytes Corrigendum in /10.3892/mmr.2020.10919

Shuya Wang, Ying Li, Wei Miao, Hong Zhao, Feng Zhang, Nan Liu, Guohai Su, Xiaojun Cai
Pages: 2607-2613
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Neuregulin-1 (Nrg1) signaling has a preventive role and is altered in the frontal cortex under the pathological conditions of Alzheimer's disease

Qiong Jiang, Shuangxi Chen, Chengliang Hu, Peizhi Huang, Huifan Shen, Weijiang Zhao
Pages: 2614-2624
Published online on: 25 July 2016

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The clinical significance of forkhead box protein A1 and its role in colorectal cancer

Wenqi Ma, Jue Jiang, Miao Li, Hua Wang, Hongli Zhang, Xin He, Lili Huang, Qi Zhou
Pages: 2625-2631
Published online on: 01 August 2016

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Article

Peripheral KATP activation inhibits pain sensitization induced by skin/muscle incision and retraction via the nuclear factor-κB/c-Jun N-terminal kinase signaling pathway

Li‑Ping Qian, Shi‑Ren Shen, Jun‑Jie Chen, Lu‑Lu Ji, Su Cao
Pages: 2632-2638
Published online on: 27 July 2016

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Article

Identification of a PTPN11 hot spot mutation in a child with atypical LEOPARD syndrome

Jia Zhang, Jinwen Shen, Ruhong Cheng, Cheng Ni, Jianying Liang, Ming Li, Zhirong Yao
Pages: 2639-2643
Published online on: 27 July 2016

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Article

Vitamin D induces autophagy of pancreatic β-cells and enhances insulin secretion

Yubin Wang, Dawei He, Chengpei Ni, Huiying Zhou, Shuyan Wu, Zhimou Xue, Zhengyu Zhou
Pages: 2644-2650
Published online on: 19 July 2016

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Article

MicroRNA-101 inhibits the proliferation and invasion of bladder cancer cells via targeting c-FOS Retraction in /10.3892/mmr.2022.12643

Yongqi Long, Zhiping Wu, Xinhua Yang, Lei Chen, Zhijun Han, Yulong Zhang, Jinge Liu, Wenjin Liu, Xinyi Liu
Pages: 2651-2656
Published online on: 20 July 2016

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Article

MicroRNA-610 is downregulated in glioma cells, and inhibits proliferation and motility by directly targeting MDM2

Yu Yan, Yong Peng, Yangzhu Ou, Yugang Jiang
Pages: 2657-2664
Published online on: 27 July 2016

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Article Open Access

Wtip is required for proepicardial organ specification and cardiac left/right asymmetry in zebrafish

Rebecca Powell, Ekaterina Bubenshchikova, Yayoi Fukuyo, Chaonan Hsu, Olga Lakiza, Hiroki Nomura, Erin Renfrew, Deborah Garrity, Tomoko Obara
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Article

Combined therapeutic effects of bortezomib and anacardic acid on multiple myeloma cells via activation of the endoplasmic reticulum stress response

Xiaoxian Dong, Yuning Liao, Ningning Liu, Xianliang Hua, Jianyu Cai, Jinbao Liu, Hongbiao Huang
Pages: 2679-2684
Published online on: 19 July 2016

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Article

Resveratrol inhibits phosphorylation within the signal transduction and activator of transcription 3 signaling pathway by activating sirtuin 1 in SW1353 chondrosarcoma cells

Haidong Jin, Hui Chen, Kehe Yu, Jingdong Zhang, Bin Li, Ningyu Cai, Jun Pan
Pages: 2685-2690
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Article

In vitro and in vivo anti-Vibrio vulnificus activity of psammaplin A, a natural marine compound

Byung Cheol Lee, Arim Lee, Jee Hyung Jung, Sang Ho Choi, Tae Sung Kim
Pages: 2691-2696
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Article

Astaxanthin blocks preeclampsia progression by suppressing oxidative stress and inflammation

Rong‑Rong Xuan, Ting‑Ting Niu, Hai‑Min Chen
Pages: 2697-2704
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CIP2A regulates proliferation and apoptosis of multiple myeloma cells

Zhuanzhen Zheng, Zhenhua Qiao, Wenliang Chen, Rong Gong, Yalin Wang, Lianrong Xu, Yanping Ma, Li Zhang, Yujin Lu, Bo Jiang, Guoxia Li, Chunxia Dong
Pages: 2705-2709
Published online on: 27 July 2016

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Case Report

Mild Camurati‑Engelamann disease presenting with exophthalmos as the first and only manifestation: A case report

Ruizhi Jiajue, Bo Wu, Yan Jiang, Ou Wang, Mei Li, Xiaoping Xing, Weibo Xia
Pages: 2710-2716
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Article

Umbilical cord-derived mesenchymal stem cells inhibit growth and promote apoptosis of HepG2 cells

Ying‑Mei Tang, Wei‑Min Bao, Jin‑Hui Yang, Lin‑Kun Ma, Jing Yang, Ying Xu, Li‑Hong Yang, Feng Sha, Zhi‑Yuan Xu, Hua‑Mei Wu, Wei Zhou, Yan Li, Yu‑Hua Li
Pages: 2717-2724
Published online on: 21 July 2016

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Article

Functional study of the upregulation of miRNA-27a and miRNA-27b in 3T3-L1 cells in response to berberine

Yue‑Yue Wu, Xin‑Mei Huang, Jun Liu, Ying Cha, Zao‑Ping Chen, Fang Wang, Jiong Xu, Li Sheng, He‑Yuang Ding
Pages: 2725-2731
Published online on: 25 July 2016

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Article

Elevated DRD4 promoter methylation increases the risk of Alzheimer's disease in males

Huihui Ji, Yunliang Wang, Danjie Jiang, Guili Liu, Xuting Xu, Dongjun Dai, Xiaohui Zhou, Wei Cui, Jinfeng Li, Zhongming Chen, Ying Li, Dongsheng Zhou, Qin Zha, Renjie Zhuo, Liting Jiang, Yu Liu, Lili Shen, Beibei Zhang, Lei Xu, Haochang Hu, Yuzheng Zhang, Honglei Yin, Shiwei Duan, Qinwen Wang
Pages: 2732-2738
Published online on: 27 July 2016

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Article

Hypermethylation of CDH13, DKK3 and FOXL2 promoters and the expression of EZH2 in ovary granulosa cell tumors

Yanmei Xu, Xia Li, Hongtao Wang, Pengmu Xie, Xun Yan, Yu Bai, Tingguo Zhang
Pages: 2739-2745
Published online on: 18 July 2016

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Article

Immunomodulatory effects of Longdan Xiegan Tang on CD4+/CD8+ T cells and associated inflammatory cytokines in rats with experimental autoimmune uveitis

Kai Tang, Dadong Guo, Lian Zhang, Junguo Guo, Fengming Zheng, Junkang Si, Hongsheng Bi
Pages: 2746-2754
Published online on: 27 July 2016

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Article

Modulatory effects of levamisole and garlic oil on the immune response of Wistar rats: Biochemical, immunohistochemical, molecular and immunological study

Essam Hassan Mohamed, Ahmed Abdel‑Aziz Baiomy, Zein Shaban Ibrahim, Mohamed Mohamed Soliman
Pages: 2755-2763
Published online on: 27 July 2016

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Article

Protective effects of ghrelin against oxidative stress, inducible nitric oxide synthase and inflammation in a mouse model of myocardial ischemia/reperfusion injury via the HMGB1 and TLR4/NF-κB pathway

Ning Sun, Hui Wang, Lin Wang
Pages: 2764-2770
Published online on: 20 July 2016

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Article

The pro-oxidant gene p66shc increases nicotine exposure-induced lipotoxic oxidative stress in renal proximal tubule cells

Istvan Arany, Samuel Hall, Dustin K. Reed, Mehul Dixit
Pages: 2771-2777
Published online on: 25 July 2016

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Article

Neuroprotective effect of ginsenoside Rg1 prevents cognitive impairment induced by isoflurane anesthesia in aged rats via antioxidant, anti-inflammatory and anti-apoptotic effects mediated by the PI3K/AKT/GSK-3β pathway

Yini Zhang, Zhao Zhang, Haitang Wang, Nan Cai, Shuang Zhou, Yaoping Zhao, Xue Chen, Shaoqiang Zheng, Qi Si, Wei Zhang
Pages: 2778-2784
Published online on: 27 July 2016

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Article

Synergy between von Hippel-Lindau and P53 contributes to chemosensitivity of clear cell renal cell carcinoma

Ziyi Zhao, Changjin Chen, Junzhi Lin, Wentong Zeng, Juan Zhao, Yindan Liang, Qinrui Tan, Chao Yang, Hui Li
Pages: 2785-2790
Published online on: 27 July 2016

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Article

Atorvastatin ameliorates endothelium-specific insulin resistance induced by high glucose combined with high insulin

Ou Yang, Jinliang Li, Haiyan Chen, Jie Li, Jian Kong
Pages: 2791-2798
Published online on: 27 July 2016

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Article

Celastrol inhibits IL-1β-induced inflammation in orbital fibroblasts through the suppression of NF-κB activity

Hong Li, Yifei Yuan, Yali Zhang, Qianwen He, Rongjuan Xu, Fangfang Ge, Chen Wu
Pages: 2799-2806
Published online on: 28 July 2016

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Article

Prenatal valproate treatment produces autistic-like behavior and increases metabotropic glutamate receptor 1A-immunoreactivity in the hippocampus of juvenile rats

Francisco Peralta, Constanza Fuentealba, Jenny Fiedler, Esteban Aliaga
Pages: 2807-2814
Published online on: 18 July 2016

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Article

Expression of interferon regulatory factor 5 is regulated by the Sp1 transcription factor

Jin Shu, Xiao‑Hua Wang, Lan‑Bo Zhou, Chun‑Ming Jiang, Wei‑Xia Yang, Rui Jin, Lu‑Lu Wang, Guo‑Ping Zhou
Pages: 2815-2822
Published online on: 27 July 2016

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Article

Identifying the role of Wilms tumor 1 associated protein in cancer prediction using integrative genomic analyses

Li‑Sheng Wu, Jia‑Yi Qian, Minghai Wang, Haiwei Yang
Pages: 2823-2831
Published online on: 18 July 2016

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Article

Effect of evodiamine on the proliferation and apoptosis of A549 human lung cancer cells

Li Lin, Li Ren, Liujing Wen, Yu Wang, Jin Qi
Pages: 2832-2838
Published online on: 29 July 2016

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Article

Photoprotective properties of 20(S)-protopanaxatriol, an aglycone of ginseng saponins: Protection from ultraviolet-B radiation-induced oxidative stress in human epidermal keratinocytes

Sun‑Joo Oh, Kyunghoon Kim, Chang‑Jin Lim
Pages: 2839-2845
Published online on: 01 August 2016

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Article

Downregulation of AATK mediates microRNA-558-induced resistance of A549 cells to radiotherapy

Rui‑Xia Zhu, Chun‑Hui Song, Jin‑Shan Yang, Qing‑Ting Yi, Bao‑Jian Li, Si‑Hai Liu
Pages: 2846-2852
Published online on: 01 August 2016

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Article

Nitidine chloride inhibits proliferation, induces apoptosis via the Akt pathway and exhibits a synergistic effect with doxorubicin in ovarian cancer cells

Feng Ding, Tianfeng Liu, Nina Yu, Shihong Li, Xiaofei Zhang, Guanghong Zheng, Chunming Lv, Kai Mou, Jia Xu, Bo Li, Surong Wang, Haibo Song
Pages: 2853-2859
Published online on: 29 July 2016

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Article

MicroRNA-26a protects against cardiac hypertrophy via inhibiting GATA4 in rat model and cultured cardiomyocytes

Yan Liu, Zhiqian Wang, Wenliang Xiao
Pages: 2860-2866
Published online on: 28 July 2016

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Article

miR-22-5p revealed as a potential biomarker involved in the acute phase of myocardial infarction via profiling of circulating microRNAs

Agata Maciejak, Marek Kiliszek, Grzegorz Opolski, Agnieszka Segiet, Krzysztof Matlak, Slawomir Dobrzycki, Dorota Tulacz, Grazyna Sygitowicz, Beata Burzynska, Monika Gora
Pages: 2867-2875
Published online on: 27 July 2016

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FOXJ3 drives mesenchymal stem cell osteogenic differentiation via the Wnt/β‑catenin pathway: A novel regulator implicated in osteoporosis

Hongwei Xiao, Jianfeng Li, Wei Huang, Yi Qin
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Jian Li, Dong Zhen, Yuhuan Qin, Caifen Guo
Article Number: 49
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Glabridin attenuates LTA‑induced alveolar macrophage migration via activation of the Nrf2/HO‑1 pathway

Chih-Hsuan Hsia, Chun-Ming Yang, Chao-Chien Chang, Ting-Lin Yen, Arief Gunawan Darmanto, Chi-Chang Huang, Joen-Rong Sheu
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Article Number: 46
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TGM1 as a novel signature gene in psoriasis identified by integrative bioinformatics and experimental validation

Pan Guo, Mengke Sun, Jingyu Zhang, Qianshu Yuan, Hong Cui, Junkai Huang, Jing Luo, Qianyu Zhu, Bingxin Zhang, Lizhi Hu
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CDK1‑induced regulation of p53 phosphorylation at Ser315 mediates cell cycle arrest and apoptosis of macrophages infected with clinical isolates of Mycobacterium tuberculosis

Banghao Sun, Zhenyu Zhao, Qingyu Meng, Luya Pu, Xingyu Jiang, Shuai Li, Fadi Cao, Fan Li
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High‑intensity exercise training inhibits excessive autophagy in the hyperlipidemic myocardium of ApoE‑/‑ mice via the NAD+‑mediated SIRT1/MFN2 pathway

Shan Gao, Wei Yao, Jin Yang, Yujie Liu, Zuowei Pei
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Correction Open Access

[Corrigendum] Protective effects of metformin against myocardial ischemia‑reperfusion injury via AMPK‑dependent suppression of NOX4

Yan Shi, Shu-Ai Hou
Article Number: 42
Published online on: 17 November 2025

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Apelin promotes RANKL‑mediated osteoclastogenesis by activating MAPK and NF‑κB pathways

Yu-Han Wang, Yu-Ying Wu, Chun-Hao Tsai, Yi-Chin Fong, Chih-Yuan Ko, Hsien-Te Chen, Yat-Yin Law, Chih-Hsin Tang
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Identification of multimorbidity hub genes for knee osteoarthritis-atherosclerosis and potential clinical applications

Qingyuan Kang, Ping Yuan, Peisen Xie, Wentao Xiao, Liguang Dong, Zhenpeng Guan, Keshi Zhang
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CTSB mediates oxidative stress and intestinal epithelial barrier disruption in intestinal ischemia‑reperfusion injury

Shuang He, Lei Wang, Zhe Wang, Shiyong Yu, Qi Zhu, Yijun Xu, Yuhang Jiang, Yingxia Wu, Honggang Xiang
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Astragaloside IV promotes the apoptosis of pancreatic cancer cells by activating endoplasmic reticulum stress through the PERK/ATF4/CHOP signaling pathway

Yijun Wang, Mengyang Zhao, Shanshan Liu, Rui Zheng, Tianhui Gao
Article Number: 38
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Retraction Open Access

[Retracted] Baicalin inhibits influenza virus A replication via activation of type I IFN signaling by reducing miR‑146a

Rui Li, Lianxin Wang
Article Number: 37
Published online on: 10 November 2025

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Yuanliang Cao, Quan Wan, Boqi Zhou, Haixin Zeng, Xiaojie Lu
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Diabetic keratopathy and nuclear proteins (Review)

Haiying Xu, Zhi-Liang Jiang, Yuehong Wang, Xiaoli Hou, Weixia Dong, Yanfang Chen, Qiuying Zhang, Xinying Ji, Shaoping Ji, Yalong Dang
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Homocystinuria: Advances in metabolic and molecular therapies targeting homocysteine pathways (Review)

Ayman A. Althubity
Article Number: 34
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Synovial chondromatosis: Novel advances in understanding the pathogenesis and in diagnostic strategies (Review)

Xingzheng Deng, Shizhang Liu, Huitong Liu
Article Number: 33
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Protective effects of Notoginsenoside R1 on the ferroptosis of a human non‑small cell lung cancer cell line

Yuejiao Zhang, Zhongshun Mao, Yong Diao
Article Number: 32
Published online on: 06 November 2025

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Unraveling the synergy of inflammation and apoptosis in sepsis-induced acute lung injury: Insights and therapeutic perspectives (Review)

Liwen Zhang, Haoxuan Li, Dongxu Li, Qingqing Dai
Article Number: 31
Published online on: 03 November 2025

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Dihydroalterperylenol from endophytic fungus Alternaria semiverrucosa and its antitumour activity uncovered by transcriptome analysis, molecular docking and molecular dynamics simulations

Mingfei Yang, Yongzhong Lu, Long Han, Zhangjiang He, Jichuan Kang
Article Number: 30
Published online on: 03 November 2025

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[Retracted] Phosphoinositide 3‑kinase/Akt pathway is involved in pingyangmycin‑induced growth inhibition, apoptosis and reduction of invasive potential in EOMA mouse hemangioendothelioma cells

Li-Xia Peng, Ping Zhao, Hong-Sheng Zhao, Er Pan, Bin-Bin Yang, Qin Li
Article Number: 29
Published online on: 03 November 2025

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Tight junction dysfunction and cytoskeletal remodeling in Hirschsprung‑associated enterocolitis: A decade of mechanistic insights and therapeutic prospects (Review)

Shuai Li, Chen Wang, Ling Zhang, Shan Chen, Ying Zhou, Dehua Yang, Kang Li, Yuan Liu, Shuiqing Chi, Yong Wang, Lizhi Li, Shao-Tao Tang
Article Number: 28
Published online on: 03 November 2025

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Involvement of the thioredoxin system in multiple diseases: A focus on mechanisms of action in autophagy and ferroptosis (Review)

Weihua Wang, Yingdong Mou, Dunlin Lu, Shanshan Xu
Article Number: 27
Published online on: 03 November 2025

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MicroRNA‑199a‑3p suppresses non‑small cell lung cancer progression by targeting FTO to enhance m6A‑mediated downregulation of MZF1 and its transcriptional activation of CLDND1

Yuzhen Cui, Xiaoqian Li, Hongkui Zhang, Weiqiang Yuan, Enbo Zhu
Article Number: 26
Published online on: 03 November 2025

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Role of ubiquitin‑proteasome system in preeclampsia (Review)

Chang-Zhu Pei, Xiao-Xing Song, Hao Xu, Kwang-Hyun Baek
Article Number: 25
Published online on: 03 November 2025

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Schisantherin A induces ferroptosis in non‑small cell lung cancer through activation of the YAP/ACSL4/TfR signaling pathway

Wenxiang Zhu, Yeyang Chen, Xiangjian Wu, Xiaoyan Fu, Yongshi He, Yuxia Mo, Qinghua Zhu, Mingwen Tang, Zhiguang Zhai
Article Number: 24
Published online on: 03 November 2025

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The gut‑bone‑cartilage triad: Microbial regulation of the Wnt/β‑catenin signaling pathway in osteoarthritis joint remodeling (Review)

Ruipu Zhang, Liang Zhang, Bin Tian, Yiqun Wang, Xin Kang, Jiang Zheng
Article Number: 23
Published online on: 31 October 2025

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Protective impact of landiolol against acute lung injury following hemorrhagic shock and resuscitation in rats

Risa Sakamoto, Hiroko Shimizu, Ryu Nakamura, Yifu Lu, Yaqiang Li, Emiko Omori, Toru Takahashi, Hiroshi Morimatsu
Article Number: 22
Published online on: 31 October 2025

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Hidden connection: Impact of the gut microbiota on respiratory diseases in children (Review)

Yanhua Han, Yuchao Jia, Lili Chen, Mingyao Zhang
Article Number: 21
Published online on: 29 October 2025

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From renal development to pathology: An analysis of the multilevel role of insulin‑like growth factor 2 (Review)

Yuping Sun, Wenke Hao, Wei Liu, Wenxue Hu
Article Number: 20
Published online on: 29 October 2025

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[Corrigendum] Early anticoagulation therapy for severe burns complicated by inhalation injury in a rabbit model

Zhong-Hua Fu, Guang-Hua Guo, Zhen-Fang Xiong, Xincheng Liao, Ming-Zhuo Liu, Jinhua Luo
Article Number: 19
Published online on: 29 October 2025

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Mucin 2 and unfolded protein response reshape the mucus barrier in inflammatory bowel disease (Review)

Zhiwei Yuan, Zheng Xia, Liyun Ling, Jingzhe Xie, Feng Zhang
Article Number: 18
Published online on: 29 October 2025

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RING finger protein family in leukemia (Review)

Ye Wang, Yue Zhao, Jihong Zhang
Article Number: 17
Published online on: 29 October 2025

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Retinal light perception and biological rhythms: The role of light in sleep and mood from an ophthalmic perspective (Review)

Man Yuan, Hanxiang Liu, Ranjie Zhu, Yuzhen Li, Siyuan Song, Anhuai Yang
Article Number: 16
Published online on: 29 October 2025

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[Retracted] Oxymatrine‑mediated maturation of dendritic cells leads to activation of FOXP3+/CD4+ Treg cells and reversal of cisplatin‑resistance in lung cancer cells

Hui Liu, Manman Zou, Pei Li, Haifeng Wang, Xijun Lin, Jin Ye
Article Number: 15
Published online on: 27 October 2025

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Zinc finger protein 514 promotes esophageal cancer progression by enhancing cell proliferation, migration and invasion

Lin Lv, Xiaoming Sun, Houlu Zhang, Guangxu Wang, Chao Zhang, Haibo Liu, Liangming Zhu
Article Number: 14
Published online on: 24 October 2025

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Effects of zinc carnosine on bone loss in mice with diabetic osteoporosis 

Jingyuan Gao, Hao Yang, Qiangqiang Lian, Yunpeng Hu, Zhou Yang, Lei Xing, Ying Xue, Xiaoli Hou, Faming Tian, Dong Hu
Article Number: 13
Published online on: 24 October 2025

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Rapamycin improves endometriosis‑related infertility involving ovarian senescence via the PPARα/IGFBP2 pathway

Qiongwei Wu, Jiao Fan, Qingjing Sheng, Xiaoying He
Article Number: 12
Published online on: 24 October 2025

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Combining tadalafil and hyperbaric oxygen therapy protects against ovarian ischemia‑reperfusion damage in rats

Mehmet Akif Baktir, Mustafa Ermis, Esra Balcioglu, Betul Yalcin, Enes Karaman, Ahmet Cumaoglu
Article Number: 11
Published online on: 23 October 2025

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Liquid‑liquid phase separation of PHLDB2 promotes oral squamous cell carcinoma metastasis through regulating epithelial mesenchymal transition and PIK3CA expression

Kunyi Chen, Yuhong Wang, Jianing Cui, Qianrui Liu, Xiaoyong Liu, Wenjin Wang, Jinsong Hou
Article Number: 10
Published online on: 22 October 2025

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Mitochondrial gatekeeper in hepatocellular carcinoma: Unraveling the multifaceted roles of VDAC in metabolic reprogramming, apoptosis evasion and therapeutic innovation (Review)

Jie Wang, Yu Liang, Xiaotao Jia, Xinmao Yang, Danning Shi, Yuanchun Wang, Yanfang Pan
Article Number: 9
Published online on: 21 October 2025

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[Retracted] Knockdown of ubiquitin‑specific protease 51 attenuates cisplatin resistance in lung cancer through ubiquitination of zinc‑finger E‑box binding homeobox 1

Feng Zhou, Chunling Du, Donghui Xu, Jinchang Lu, Lei Zhou, Chaomin Wu, Bo Wu, Jianan Huang
Article Number: 8
Published online on: 20 October 2025

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Exploring the role of cytochrome P450 family 1 subfamily B member 1 and quercetin in modulating neuropathic pain after spinal cord injury

Pengyu Zhou, Lu Li, Yu Cao, Jiahao Chen, Chuyin Chen, Xiangsheng Zhang, Jiurong Chen, Yingdong Deng, Ziqiang Lin, Yupei Lai, Suo Wang, Simin Tang, Wenqi Zhang, Peng Sun, Jun Zhou
Article Number: 7
Published online on: 15 October 2025

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R‑loops in hepatocellular carcinoma: Bridging genomic instability and therapeutic opportunity (Review)

Ching-Hua Hsieh, Yueh-Wei Liu, Pei-Chin Chuang
Article Number: 6
Published online on: 15 October 2025

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Role and relevance of exosome-mediated epigenetic regulation in the pathogenesis, diagnosis and treatment of 
cardiovascular diseases (Review)

Yishuo Zhang, Shanshan Zhang, Yijing Li, Wenqi Jin, Liya Zhou, Jing Lu
Article Number: 5
Published online on: 15 October 2025

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PLIN5 deficiency ameliorates metabolic dysfunction‑associated fatty liver disease by inhibiting ferroptosis

Ya Li, Xiaohan Wang, Xuecui Yin, Xiaohui Zhu, Weiqi Cui, Lin Dong, Yu Xia, Ying Wang, Liu Liu, Pengyuan Zheng, Youcai Tang
Article Number: 4
Published online on: 14 October 2025

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Circadian clock genes: Their influence on liver metabolism, disease development and treatment (Review)

Junmin Wang, Mengxing Cao, Shen Li, Wen Pei, Jing Li, Zhen Wang
Article Number: 3
Published online on: 14 October 2025

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MALT1 inhibition by MI‑2 suppresses epithelial‑to‑mesenchymal transition and fibrosis by inactivating the NF‑κB pathway in high glucose‑treated HK‑2 cells

Yating Lan, Jian Ma, Huijun Chen, Chaohong Lan, Na Zhao
Article Number: 2
Published online on: 14 October 2025

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[Retracted] Protective effect of erythropoietin against myocardial injury in rats with sepsis and its underlying mechanisms

Xinliang Zhang, Shimin Dong, Yanjun Qin, Xiaohua Bian
Article Number: 1
Published online on: 14 October 2025

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February-2026 Volume 33 Issue 2

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Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

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Mitophagy and oxidative stress in chronic kidney disease (Review)

Quwu Mushuo, Yihuai Tian, Jianchun Li, Yanqin Qiu, Hui Fan, Qiongdan Hu, Qiong Zhang
Article Number: 61
Published online on: 04 December 2025

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ABCC9 knockdown attenuates isoproterenol‑induced myocardial hypertrophy by inhibiting the PI3K/AKT signaling pathway

Qian Peng, Rui Chang, Linlin Ma, Yanfei Li
Article Number: 60
Published online on: 04 December 2025

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MeCP2 suppresses ferroptosis to drive EMT in retinal pigment epithelial cells: Implications for PVR pathogenesis

Sibei Guo, Yongya Zhang, Xue Li, Xueru Zhao, Yingjuan Liang, Xiaohua Li
Article Number: 59
Published online on: 04 December 2025

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[Corrigendum] Screening for implicated genes in colorectal cancer using whole‑genome gene expression profiling

Long-Ci Sun, Hai-Xin Qian
Article Number: 58
Published online on: 04 December 2025

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Hyperoside prevents osteoporosis by activating the PI3K/AKT signaling pathway to inhibit oxidative stress and promote osteogenesis

Lirong Li, Huaidong Deng, Shabin Zhuan, Boyu Wu, Dawei Xiao
Article Number: 57
Published online on: 03 December 2025

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[Retracted] Interference with Tim‑3 protein expression attenuates the invasion of clear cell renal cell carcinoma and aggravates anoikis

Muming Yu, Bin Lu, Yancun Liu, Ying Me, Lijun Wang, Hui Li
Article Number: 56
Published online on: 01 December 2025

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Acetylshikonin induces ferroptosis via the lipid peroxidation pathway in osteosarcoma cells

Ji-Ying Chen, Guo-Shou Wang, Tsung-Ming Chang, Ju-Fang Liu
Article Number: 55
Published online on: 27 November 2025

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Liver X receptor: A potential target for inflammatory bowel disease and colorectal cancer (Review)

Yingjie Li, Xiaoyan Fu, Meiwen Bai, Jiaqi Zhou, Jiatai Qiu, Hongxia Zhang, Shujuan Liang, Meifang Liu
Article Number: 54
Published online on: 27 November 2025

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lncRNA NEAT1 promotes the proliferation of hemangioma cells by transcriptionally activating β‑catenin via enhancing H3K18 lactylation

Li Yu, Nian Zhou, Xiao-Liang Zhang, Xue-Jing Pang, Lu Xing, Yun-Jing Pu, Li Zhang, Jing-Nan Wu, Hong Shu
Article Number: 53
Published online on: 25 November 2025

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[Retracted] MicroRNA‑206 exerts anti‑oncogenic functions in esophageal squamous cell carcinoma by suppressing the c‑Met/AKT/mTOR pathway

Jin Zhang, Xianen Fa, Qingyong Zhang
Article Number: 52
Published online on: 25 November 2025

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