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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
September-2016 Volume 14 Issue 3

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Journal Metrics

Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review

Potential use of visible and near-infrared spectroscopy for the analysis and diagnosis of chronic fatigue syndrome (Review)

Akikazu Sakudo
Pages: 1875-1879
Published online on: 07 July 2016

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Article Open Access

Evaluation of urinary bladder fibrogenesis in a mouse model of long-term ketamine injection

Cheng‑Huang Shen, Shou‑Chieh Wang, Shou‑Tsung Wang, Shu‑Mei Lin, Jiann‑Der Wu, Chang‑Te Lin, Yi‑Wen Liu
Pages: 1880-1890
Published online on: 07 July 2016

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Article Open Access

Disruption of kif3a results in defective osteoblastic differentiation in dental mesenchymal stem/precursor cells via the Wnt signaling pathway

Sicong Jiang, Guoqing Chen, Lian Feng, Zongting Jiang, Mei Yu, Jinku Bao, Weidong Tian
Pages: 1891-1900
Published online on: 12 July 2016

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Article Open Access

Slit2‑Robo1 signaling promotes the adhesion, invasion and migration of tongue carcinoma cells via upregulating matrix metalloproteinases 2 and 9, and downregulating E‑cadherin

Yuan Zhao, Feng-Li Zhou, Wei‑Ping Li, Jing Wang, Li‑Jing Wang
Pages: 1901-1906
Published online on: 13 July 2016

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Article Open Access

Bufalin suppresses cancer stem-like cells in gemcitabine-resistant pancreatic cancer cells via Hedgehog signaling

Haiyong Wang, Zhouyu Ning, Yingyi Li, Xiaoyan Zhu, Zhiqiang Meng
Pages: 1907-1914
Published online on: 06 July 2016

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Article Open Access

Caveolin-1 is critical in the proliferative effect of leptin on osteoblasts through the activation of Akt

Lin Zou, Guichun Zhang, Lifeng Liu, Chen Chen, Xuecheng Cao, Jinfang Cai
Pages: 1915-1922
Published online on: 01 July 2016

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Article Open Access

The effect of LOXL2 in hepatocellular carcinoma

Linghong Wu, Yuan Zhang, Ying Zhu, Qingwei Cong, Yan Xiang, Linlin Fu
Pages: 1923-1932
Published online on: 06 July 2016

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Article Open Access

Expression and clinical significance of Apollon in esophageal squamous cell carcinoma

Rong Li, Bo‑Lin Chen, Yan‑Wu Zhou, Ren‑Wei Guo, Meng‑Ting Shuai, Jun‑Xian Zeng, Ai‑Min Leng
Pages: 1933-1940
Published online on: 06 July 2016

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Article Open Access

Molecular analysis of FGFR 2 and associated clinical observations in two Chinese families with Crouzon syndrome

Ying Lin, Hongbin Gao, Siming Ai, Jacob V.P. Eswarakumar, Tao Li, Bingqian Liu, Hongye Jiang, Yuhua Liu, Xialin Liu, Yonghao Li, Yao Ni, Jiangna Chen, Zhuoling Lin, Xiaoling Liang, Chenjin Jin, Xinhua Huang, Lin Lu, Yizhi Liu
Pages: 1941-1946
Published online on: 11 July 2016

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Article Open Access

HIV‑1 downregulates the expression and phosphorylation of receptor tyrosine kinase by targeting the NF‑κB pathway

Tingting Feng, Jianhe Gan, Ailan Qin, Xiaoping Huang, Nanping Wu, Hua Hu, Hangping Yao
Pages: 1947-1952
Published online on: 08 July 2016

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Article Open Access

mRNA expression of TLR4, TLR9 and NF-κB in a neonatal murine model of necrotizing enterocolitis

Yiyu Yin, Fengli Liu, Yiping Li, Ruze Tang, Jian Wang
Pages: 1953-1956
Published online on: 29 June 2016

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Article Open Access

Aspirin inhibits osteoclastogenesis by suppressing the activation of NF-κB and MAPKs in RANKL-induced RAW264.7 cells

Yan‑Ping Zeng, Chao Yang, Yuan Li, Yong Fan, Hong‑Jun Yang, Bin Liu, Hong‑Xun Sang
Pages: 1957-1962
Published online on: 30 June 2016

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Article Open Access

Antioxidant effect of angiotensin (1‑7) in the protection of pancreatic β cell function

Fen Zhang, Chang Liu, Lei Wang, Xi Cao, Ying Ying Wang, Jin Kui Yang
Pages: 1963-1969
Published online on: 13 July 2016

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Article Open Access

A novel manganese complex selectively induces malignant glioma cell death by targeting mitochondria

Ji Geng, Jing Li, Tao Huang, Kaidi Zhao, Qiuyun Chen, Wenjie Guo, Jing Gao
Pages: 1970-1978
Published online on: 12 July 2016

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Article Open Access

Endothelial lipase is upregulated by interleukin-6 partly via the p38 MAPK and p65 NF-κB signaling pathways

Xin Yue, Minghui Wu, Hong Jiang, Jing Hao, Qinghao Zhao, Qing Zhu, Gaowa Saren, Yun Zhang, Xiaoli Zhang
Pages: 1979-1985
Published online on: 30 June 2016

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Article Open Access

Luteolin decreases the UVA‑induced autophagy of human skin fibroblasts by scavenging ROS

Miaomiao Yan, Zhongrong Liu, Huilan Yang, Cuihua Li, Hulin Chen, Yan Liu, Minling Zhao, Yingjie Zhu
Pages: 1986-1992
Published online on: 13 July 2016

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Article Open Access

Directed differentiation of postnatal hippocampal neural stem cells generates nuclear receptor related‑1 protein‑ and tyrosine hydroxylase‑expressing cells

Yinxiu Ding, Zixin Zhang, Jiangbo Ma, Hechun Xia, Yin Wang, Yinming Liu, Quanrui Ma, Tao Sun, Juan Liu
Pages: 1993-1999
Published online on: 08 July 2016

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Article Open Access

Investigation of the anti‑asthmatic activity of Oridonin on a mouse model of asthma

Jing Wang, Fengsen Li, Jianbing Ding, Ge Tian, Min Jiang, Zhen Gao, Ehbal Tuyghun
Pages: 2000-2006
Published online on: 08 July 2016

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Article Open Access

Protection of rat liver against hepatic ischemia-reperfusion injury by a novel selenocysteine-containing 7-mer peptide

Qianqian Jiang, Yu Pan, Yupeng Cheng, Huiling Li, Hui Li
Pages: 2007-2015
Published online on: 01 July 2016

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Article Open Access

Inhibitor of DNA binding 1 regulates cell cycle progression of endothelial progenitor cells through induction of Wnt2 expression

Xi Xia, Yang Yu, Li Zhang, Yang Ma, Hong Wang
Pages: 2016-2024
Published online on: 08 July 2016

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Article Open Access

Effects of imatinib and nilotinib on the whole transcriptome of cultured murine osteoblasts

Gyöngyi Kirschner, Bernadett Balla, Péter Horváth, Andrea Kövesdi, Gergely Lakatos, István Takács, Zsolt Nagy, Bálint Tóbiás, Kristóf Árvai, János Pál Kósa, Péter Lakatos
Pages: 2025-2037
Published online on: 30 June 2016

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Article Open Access

The expression pattern of Adam10 in the central nervous system of adult mice: Detection by in situ hybridization combined with immunohistochemistry staining

Zhi‑Bao Guo, Ying‑Ying Su, Yi‑Hui Wang, Wei Wang, Da‑Zhi Guo
Pages: 2038-2044
Published online on: 11 July 2016

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Article Open Access

Dynamic co-expression network analysis of lncRNAs and mRNAs associated with venous congestion

Jinshun Li, Yuqin Xu, Jia Xu, Jinhua Wang, Liying Wu
Pages: 2045-2051
Published online on: 07 July 2016

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Article Open Access

Role of platelet function and platelet membrane glycoproteins in children with primary immune thrombocytopenia

Wen-Jun Liu, Jing Bai, Qu-Lian Guo, Zhe Huang, Hong Yang, Yong-Qi Bai
Pages: 2052-2060
Published online on: 11 July 2016

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Article

A novel in-frame deletion in MEN1 (p.Ala416del) causes familial multiple endocrine neoplasia type 1 with an aggressive phenotype and unexpected inheritance pattern

Anna Skalniak, Grzegorz Sokołowski, Agata Jabrocka‑Hybel, Jakub Piątkowski, Magdalena Białas, Aleksandra Gilis‑Januszewska, Dorota Pach, Alicja Hubalewska‑Dydejczyk
Pages: 2061-2066
Published online on: 01 July 2016

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Article

Differential long non‑coding RNA and mRNA expression in differentiated human glioblastoma stem cells

Hao Li, Haowen Li, Yajing Hao, Yuming Jiao, Zhicen Li, Haiyan Yue, Zhe Xu, Shuo Wang, Yong Cao, Jizong Zhao
Pages: 2067-2076
Published online on: 12 July 2016

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Article

miRNA-30a functions as a tumor suppressor by downregulating cyclin E2 expression in castration-resistant prostate cancer

Lei Zhang, Xiao‑Wen Zhang, Chun‑Hui Liu, Kai Lu, Ye‑Qing Huang, Yi‑Duo Wang, Li Xing, Li‑Jie Zhang, Ning Liu, Hua Jiang, Chao Sun, Yu Yang, Shu‑Qiu Chen, Ming Chen, Bin Xu
Pages: 2077-2084
Published online on: 06 July 2016

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Article

Effects of microRNA‑338‑3p on morphine‑induced apoptosis and its underlying mechanisms

Hong‑Liang Weng, Ming‑Jing Wang
Pages: 2085-2092
Published online on: 12 July 2016

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Article

Dynamic metabolic profiling of urine biomarkers in rats with alcohol‑induced liver damage following treatment with Zhi‑Zi‑Da‑Huang decoction

Li An, Qiaoling Lang, Wenbin Shen, Qingshui Shi, Fang Feng
Pages: 2093-2100
Published online on: 11 July 2016

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Article

Enhanced expression levels of aquaporin-1 and aquaporin-4 in A549 cells exposed to silicon dioxide

Xiaohui Hao, Hongli Wang, Wei Liu, Shupeng Liu, Zihe Peng, Yue Sun, Jinyuan Zhao, Qiujie Jiang, Heliang Liu
Pages: 2101-2106
Published online on: 07 July 2016

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Article

Targeted next-generation sequencing identification of a novel missense mutation of the SKIV2L gene in a patient with trichohepatoenteric syndrome

Bixia Zheng, Jian Pan, Yu Jin, Chunli Wang, Zhifeng Liu
Pages: 2107-2110
Published online on: 11 July 2016

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Article

Silencing of osterix expression by siRNA inhibits aldosterone‑induced calcification of vascular smooth muscle cells in mice

Yan‑Chun Gong, Yue He, Hao Wang, Wen‑Quan Niu, Kai‑Da Ji, Hua Li
Pages: 2111-2118
Published online on: 08 July 2016

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Article

Sevoflurane inhibits the self-renewal of mouse embryonic stem cells via the GABAAR-ERK signaling pathway

Liuqing Yang, Yali Ge, Shunyan Lin, Xiangzhi Fang, Loujing Zhou, Ju Gao
Pages: 2119-2126
Published online on: 04 July 2016

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Article

microRNA-7 regulates cell growth, migration and invasion via direct targeting of PAK1 in thyroid cancer Retraction in /10.3892/mmr.2023.12992

Kai Yue, Xudong Wang, Yansheng Wu, Xuan Zhou, Qinghua He, Yuansheng Duan
Pages: 2127-2134
Published online on: 07 July 2016

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Article

B7-H4 expression in human infiltrating ductal carcinoma‑associated macrophages

Lei Liu, Dalin Li, Shuang Chen, Ran Zhao, Da Pang, Dianjun Li, Zhenkun Fu
Pages: 2135-2142
Published online on: 13 July 2016

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Article

Paeoniflorin inhibits proliferation and promotes apoptosis of multiple myeloma cells via its effects on microRNA‑29b and matrix metalloproteinase‑2

Shaofeng Wang, Wenhua Liu
Pages: 2143-2149
Published online on: 11 July 2016

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Article

Identification of a novel frameshift heterozygous deletion in exon 8 of the PAX6 gene in a pedigree with aniridia

Ozlem Giray Bozkaya, Esra Ataman, Ozge Aksel Kilicarslan, Tufan Cankaya, Ayfer Ulgenalp
Pages: 2150-2154
Published online on: 05 July 2016

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Article

The anti‑dengue virus properties of statins may be associated with alterations in the cellular antiviral profile expression

Owen Lloyd Bryan‑Marrugo, Daniel Arellanos-Soto, Augusto Rojas‑Martinez, Hugo Barrera‑Saldaña, Javier Ramos‑Jimenez, Roman Vidaltamayo, Ana María Rivas‑Estilla
Pages: 2155-2163
Published online on: 13 July 2016

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Article

Upregulation of kallikrein‑related peptidase 5 is associated with the malignant behavior of colorectal cancer

Yanhua Wu, Yingjian Chen, Qing Li, Yanwen Gong, Xiaohong Liu, Liquan Bi, Chengjin Hu
Pages: 2164-2170
Published online on: 13 July 2016

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Article

Suppression of tumor cell proliferation by quinine via the inhibition of the tumor necrosis factor receptor‑associated factor 6‑AKT interaction

Wenjuan Liu, Yonghao Qi, Lingyu Liu, Yu Tang, Jing Wei, Lijun Zhou
Pages: 2171-2179
Published online on: 11 July 2016

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Article

Identification of two novel mutations in the COMP gene in six families with pseudoachondroplasia

Wei‑Jia Yu, Zeng Zhang, Jin‑Wei He, Wen‑Zhen Fu, Chun Wang, Zhen‑Lin Zhang
Pages: 2180-2186
Published online on: 08 July 2016

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Article

Effects of irreversible electroporation on cervical cancer cell lines in vitro

Qin Qin, Zheng‑Ai Xiong, Ying Liu, Chen‑Guo Yao, Wei Zhou, Yuan‑Yuan Hua, Zhi‑Liang Wang
Pages: 2187-2193
Published online on: 05 July 2016

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Article

Anti‑migratory effect of rapamycin impairs allograft imaging by 18F‑fluorodeoxyglucose‑labeled splenocytes

Hukui Sun, Dayan Cheng, Yuanyuan Ma, Hong Liu, Ning Yang, Cong Zhang, Kai Wang, Guihua Hou, Huaiquan Wang
Pages: 2194-2198
Published online on: 12 July 2016

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Article

Quantitative PCR marker genes for endometrial adenocarcinoma

Alexandra C. Kölbl, Lisa‑Marie Victor, Amelie E. Birk, Udo Jeschke, Ulrich Andergassen
Pages: 2199-2205
Published online on: 07 July 2016

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Article

Alteration of the immune status of umbilical cord mesenchymal stem cells stimulated by TLR1/2 agonist, Pam3Csk

Pingxi Wang, Fanwei Zeng, Lina He, Jin Wang, Tingjiu Zhang, Dong Zhang
Pages: 2206-2212
Published online on: 13 July 2016

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Article

Confirming an integrated pathology of diabetes and its complications by molecular biomarker-target network analysis

Zide Zhao, Yingying Zhang, Fengchun Gai, Ying Wang
Pages: 2213-2221
Published online on: 07 July 2016

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Article

Inhibition of multiple myeloma cell proliferation by ginsenoside Rg3 via reduction in the secretion of IGF-1

Yan Li, Tao Yang, Jing Li, Hong‑Ling Hao, Su‑Yun Wang, Jie Yang, Jian‑Min Luo
Pages: 2222-2230
Published online on: 07 July 2016

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Article

Increased protein expression levels of pCREB, BDNF and SDF-1/CXCR4 in the hippocampus may be associated with enhanced neurogenesis induced by environmental enrichment

Xiao Qian Zhang, Jing Wei Mu, Hui Bin Wang, Jukka Jolkkonen, Ting Ting Liu, Ting Xiao, Mei Zhao, Chao Dong Zhang, Chuan Sheng Zhao
Pages: 2231-2237
Published online on: 06 July 2016

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Article

Aberrant expression of anaplastic lymphoma kinase in lung adenocarcinoma: Analysis of circulating free tumor RNA using one-step reverse transcription-polymerase chain reaction

Rossella Bruno, Mirella Giordano, Riccardo Giannini, Greta Alì, Gianfranco Puppo, Alessandro Ribechini, Antonio Chella, Gabriella Fontanini
Pages: 2238-2242
Published online on: 07 July 2016

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Article

Differential proteomics of the synovial membrane between bilateral and unilateral knee osteoarthritis in surgery‑induced rabbit models

Weilin Liu, Jian He, Ruhui Lin, Jie Liang, Qinglu Luo
Pages: 2243-2249
Published online on: 13 July 2016

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Article

Berberine enhances the anti‑tumor activity of tamoxifen in drug‑sensitive MCF‑7 and drug‑resistant MCF‑7/TAM cells

Chunjie Wen, Lanxiang Wu, Lijuan Fu, Xue Zhang, Honghao Zhou
Pages: 2250-2256
Published online on: 08 July 2016

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Article

Functional expression of human α7 nicotinic acetylcholine receptor in human embryonic kidney 293 cells

Yuan Gong, Ji‑Hong Jiang, Shi‑Tong Li
Pages: 2257-2263
Published online on: 11 July 2016

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Article

Increased levels of circulating adrenomedullin following treatment with TU‑100 in patients with Crohn's disease

Ken Kominato, Hiroshi Yamasaki, Keiichi Mitsuyama, Hidetoshi Takedatsu, Shinichiro Yoshioka, Kotaro Kuwaki, Teppei Kobayashi, Ryosuke Yamauchi, Shuhei Fukunaga, Osamu Tsuruta, Takuji Torimura
Pages: 2264-2268
Published online on: 08 July 2016

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Article

Platelet‑rich plasma promotes the migration and invasion of synovial fibroblasts in patients with rheumatoid arthritis

Shanshan Yan, Binzhou Yang, Chen Shang, Zhongshuang Ma, Zizheng Tang, Guiping Liu, Weigan Shen, Yu Zhang
Pages: 2269-2275
Published online on: 11 July 2016

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Article

Association between methylenetetrahydrofolate reductase (MTHFR) polymorphisms and susceptibility to Graves' ophthalmopathy

Jae Yeun Lee, Nam Keun Kim, Yong Wook Cho, Helen Lew
Pages: 2276-2282
Published online on: 30 June 2016

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Article

Dickkopf 2 promotes proliferation and invasion via Wnt signaling in prostate cancer

Wei Xu, Kuan Pang, Ze‑Guang Zhou, Yi‑Feng Chen, Ting Mo, Ming Li, Cheng‑Bei Liu
Pages: 2283-2288
Published online on: 11 July 2016

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Article

Pioglitazone affects the OPG/RANKL/RANK system and increase osteoclastogenesis

Fei Xu, Yonghui Dong, Xin Huang, Peng Chen, Fengjing Guo, Anmin Chen, Shilong Huang
Pages: 2289-2296
Published online on: 13 July 2016

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Article

A single nucleotide polymorphism in hsa‑miR‑146a is responsible for the development of bronchial hyperresponsiveness in response to intubation during general anesthesia

Yong Luan, Dongjiang Li, Lulu Gao, Sha Xie, Ling Pei
Pages: 2297-2304
Published online on: 11 July 2016

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Article

rs78378222 polymorphism in the 3'-untranslated region of TP53 contributes to development of age-associated cataracts by modifying microRNA-125b-induced apoptosis of lens epithelial cells

Yang Zhao, Xiao Li, Siquan Zhu
Pages: 2305-2310
Published online on: 04 July 2016

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Article

microRNA-199a-3p functions as tumor suppressor by regulating glucose metabolism in testicular germ cell tumors

Xiaowen Liu, Hongyan Duan, Shihua Zhou, Zhiyong Liu, Daobing Wu, Ting Zhao, Shan Xu, Lifang Yang, Dan Li
Pages: 2311-2320
Published online on: 06 July 2016

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Article

Protective effect of cannabidiol on hydrogen peroxide‑induced apoptosis, inflammation and oxidative stress in nucleus pulposus cells

Jie Chen, Chen Hou, Xin Chen, Dong Wang, Pinglin Yang, Xijing He, Jinsong Zhou, Haopeng Li
Pages: 2321-2327
Published online on: 13 July 2016

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Article

miRNA polymorphisms (miR‑146a, miR‑149, miR‑196a2 and miR‑499) are associated with the risk of coronary artery disease

Jung‑Hoon Sung, Sang‑Hoon Kim, Woo‑In Yang, Won‑Jang Kim, Jae‑Youn Moon, In Jai Kim, Dong‑Hun Cha, Seung‑Yun Cho, Jung Oh Kim, Kyeong Ah Kim, Ok‑Joon Kim, Sang‑Wook Lim, Nam‑Keun Kim
Pages: 2328-2342
Published online on: 11 July 2016

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Article

Endostatin and irradiation modifies the activity of ADAM10 and neprilysin in breast cancer cells

Esra Arslan Aydemir, Ece Şimşek, Aylin Fidan Korcum, Kayahan Fişkin
Pages: 2343-2351
Published online on: 01 July 2016

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Article

Apigenin inhibits glioma cell growth through promoting microRNA-16 and suppression of BCL-2 and nuclear factor-κB/MMP‑9

Xin‑Jun Chen, Mian‑Yun Wu, Deng‑Hui Li, Jin You
Pages: 2352-2358
Published online on: 30 June 2016

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Article

Cytotoxic effects of NF‑κB inhibitors in combination with anti‑herpes agents on Epstein‑Barr virus‑positive gastric carcinoma in vitro

Paula Ordonez, Athira Nandakumar, Chihaya Koriyama, Megumi Yamomoto, Suminori Akiba
Pages: 2359-2367
Published online on: 11 July 2016

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Article

Emodin‑8‑O‑glucuronic acid, from the traditional Chinese medicine qinghuobaiduyin, affects the secretion of inflammatory cytokines in LPS‑stimulated raw 264.7 cells via HSP70

Ping Wang, Quanyong He, Jie Zhu
Pages: 2368-2372
Published online on: 13 July 2016

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Article Open Access

Application of network construction to estimate functional changes to insulin receptor substrates 1 and 2 in Huh7 cells following infection with the hepatitis C virus

Jingkun Liu, Linbang Wang, Wenjun Wang, Yaping Li, Xiaoli Jia, Song Zhai, Juan Shi, Shuangsuo Dang
Pages: 2379-2388
Published online on: 18 July 2016

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The protective role of vitamin D3 in a murine model of asthma via the suppression of TGF-β/Smad signaling and activation of the Nrf2/HO-1 pathway

Zhihui Wang, Haitao Zhang, Xiaohan Sun, Lihong Ren
Pages: 2389-2396
Published online on: 27 July 2016

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Therapeutic effects of paeonol on methyl-4-phenyl-1,2,3,6-tetrahydropyridine/probenecid-induced Parkinson's disease in mice

Xiaojin Shi, Yu‑Hua Chen, Hao Liu, Hong‑Dang Qu
Pages: 2397-2404
Published online on: 28 July 2016

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Article

Proteomic analysis of the effects of CSF-1 and IL-1α on dental follicle cells

Chanchan Chen, Nan Xie, Junqi Ling, Yu Du, Haijing Gu
Pages: 2405-2414
Published online on: 28 July 2016

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Telocytes as potential targets in a cyclophosphamide-induced animal model of premature ovarian failure

Te Liu, Suwei Wang, Qiong Li, Yongyi Huang, Chuan Chen, Jin Zheng
Pages: 2415-2422
Published online on: 22 July 2016

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Trichostatin A increases the TIMP-1/MMP ratio to protect against osteoarthritis in an animal model of the disease

Hao Qu, Jin Li, Li‑Dong Wu, Wei‑Ping Chen
Pages: 2423-2430
Published online on: 18 July 2016

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Co-expression of ING4 and P53 enhances hypopharyngeal cancer chemosensitivity to cisplatin in vivo

Xin Ren, Hao Liu, Mingjie Zhang, Mengjun Wang, Shiyin Ma
Pages: 2431-2438
Published online on: 27 July 2016

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Molecular analysis of myocilin and optineurin genes in Korean primary glaucoma patients

Joonhong Park, Myungshin Kim, Chan Kee Park, Hyojin Chae, Seungok Lee, Yonggoo Kim, Woori Jang, Hyun Young Chi, Hae‑Young Lopilly Park, Shin Hae Park
Pages: 2439-2448
Published online on: 27 July 2016

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Semaphorin 3A-modified adipose-derived stem cell sheet may improve osseointegration in a type 2 diabetes mellitus rat model

Kaixiu Fang, Wen Song, Lifeng Wang, Xiaoru Xu, Naiwen Tan, Sijia Zhang, Hongbo Wei, Yingliang Song
Pages: 2449-2456
Published online on: 28 July 2016

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Periodic mechanical stress induces the extracellular matrix expression and migration of rat nucleus pulposus cells by upregulating the expression of intergrin α1 and phosphorylation of downstream phospholipase Cγ1

Gongming Gao, Jin He, Luming Nong, Hua Xie, Yongjing Huang, Nanwei Xu, Dong Zhou
Pages: 2457-2464
Published online on: 27 July 2016

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LncRNA HOTAIR controls the expression of Rab22a by sponging miR-373 in ovarian cancer Retraction in /10.3892/mmr.2024.13346

Zhongbao Zhang, Jiajing Cheng, Yi Wu, Jin Qiu, Yi Sun, Xiaowen Tong
Pages: 2465-2472
Published online on: 28 July 2016

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Article Open Access

Wnt3a is critical for endothelial progenitor cell-mediated neural stem cell proliferation and differentiation

Yibin Du, Shuo Zhang, Tao Yu, Gongwen Du, Hui Zhang, Zongsheng Yin
Pages: 2473-2482
Published online on: 01 August 2016

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Resistant mechanisms and molecular epidemiology of imipenem-resistant Acinetobacter baumannii

Shu‑Zhen Xiao, Hai‑Qing Chu, Li‑Zhong Han, Zhe‑Min Zhang, Bing Li, Lan Zhao, Liyun Xu
Pages: 2483-2488
Published online on: 22 July 2016

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Downregulation of thrombospondin-1 by DNA hypermethylation is associated with tumor progression in laryngeal squamous cell carcinoma

Chuang Huang, Xiaohong Zhou, Zhenhua Li, Hong Liu, Yun He, Guo Ye, Kun Huang
Pages: 2489-2496
Published online on: 01 August 2016

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Cerebral vasoconstriction reactions and plasma levels of ETBR, ET-1, and eNOS in patients with chronic high altitude disease

Shizheng Wu, Guisheng Hao, Shukun Zhang, Dongmei Jiang, Tana Wuren, Junming Luo
Pages: 2497-2502
Published online on: 27 July 2016

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MicroRNA-363 and GATA-1 are regulated by HIF-1α in K562 cells under hypoxia

Youbang Xie, Wenqian Li, Jianming Feng, Tianyi Wu, Jianping Li
Pages: 2503-2510
Published online on: 29 July 2016

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Effects of cisplatin on the LSD1-mediated invasion and metastasis of prostate cancer cells Retraction in /10.3892/mmr.2023.13027

Zhi‑Yuan Chen, Hui Chen, Tao Qiu, Xiao‑Dong Weng, Jia Guo, Lei Wang, Xiu‑Heng Liu
Pages: 2511-2517
Published online on: 28 July 2016

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Low-dose testosterone alleviates vascular damage caused by castration in male rats in puberty via modulation of the PI3K/AKT signaling pathway

Jing Zhao, Ge‑Li Liu, Ying Wei, Li‑Hong Jiang, Peng‑Li Bao, Qing‑Yan Yang
Pages: 2518-2526
Published online on: 27 July 2016

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Generation of porcine fetal fibroblasts expressing the tetracycline-inducible Cas9 gene by somatic cell nuclear transfer

Guoqian Liu, Kai Liu, Hengxi Wei, Li Li, Shouquan Zhang
Pages: 2527-2533
Published online on: 19 July 2016

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α-TEA inhibits the growth and motility of human colon cancer cells via targeting RhoA/ROCK signaling

Jialin Yao, Peng Gao, Yang Xu, Zhaozhu Li
Pages: 2534-2540
Published online on: 18 July 2016

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Loss of coxsackie and adenovirus receptor expression in human colorectal cancer: A potential impact on the efficacy of adenovirus-mediated gene therapy in Chinese Han population

Ying‑Yu Ma, Xiao‑Jun Wang, Yong Han, Gang Li, Hui‑Ju Wang, Shi‑Bing Wang, Xiao‑Yi Chen, Fan‑Long Liu, Xiang‑Lei He, Xiang‑Min Tong, Xiao‑Zhou Mou
Pages: 2541-2547
Published online on: 21 July 2016

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Co-expression of autophagic markers following photodynamic therapy in SW620 human colon adenocarcinoma cells

Barbara Ziółkowska, Marta Woźniak, Piotr Ziółkowski
Pages: 2548-2554
Published online on: 25 July 2016

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Analysis of different components in the peritumoral tissue microenvironment of colorectal cancer: A potential prospect in tumorigenesis Corrigendum in /10.3892/mmr.2016.5882

Chao Huang, Hong Liu, Xiuli Gong, Bin Wen, Dan Chen, Jinyuan Liu, Fengliang Hu
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Dysregulated function of normal human epidermal keratinocytes in the absence of filaggrin

Ningning Dang, Xiaoli Ma, Xianguang Meng, Liguo An, Shuguang Pang
Pages: 2566-2572
Published online on: 22 July 2016

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Rescued expression of WIF-1 in gallbladder cancer inhibits tumor growth and induces tumor cell apoptosis with altered expression of proteins

Yan Huang, Qiang Du, Weibao Wu, Feifei She, Yanling Chen
Pages: 2573-2581
Published online on: 19 July 2016

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Neuroprotection induced by post-conditioning following ischemia/reperfusion in mice is associated with altered microRNA expression

Wei Miao, Tian‑Hao Bao, Jian‑Hong Han, Mei Yin, Jie Zhang, Yong Yan, Yu‑Hong Zhu
Pages: 2582-2588
Published online on: 29 July 2016

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Zisheng Shenqi decoction ameliorates monosodium urate crystal-induced gouty arthritis in rats through anti-inflammatory and anti-oxidative effects

Jieru Han, Ying Xie, Fangyu Sui, Chunhong Liu, Xiaowei Du, Chenggang Liu, Xiaoling Feng, Deyou Jiang
Pages: 2589-2597
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Tumorigenic lung tumorospheres exhibit stem-like features with significantly increased expression of CD133 and ABCG2

Wensi Zhao, Yi Luo, Boyi Li, Tao Zhang
Pages: 2598-2606
Published online on: 18 July 2016

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Angiopoietin-like protein 2 expression is suppressed by angiotensin II via the angiotensin II type 1 receptor in rat cardiomyocytes Corrigendum in /10.3892/mmr.2020.10919

Shuya Wang, Ying Li, Wei Miao, Hong Zhao, Feng Zhang, Nan Liu, Guohai Su, Xiaojun Cai
Pages: 2607-2613
Published online on: 25 July 2016

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Neuregulin-1 (Nrg1) signaling has a preventive role and is altered in the frontal cortex under the pathological conditions of Alzheimer's disease

Qiong Jiang, Shuangxi Chen, Chengliang Hu, Peizhi Huang, Huifan Shen, Weijiang Zhao
Pages: 2614-2624
Published online on: 25 July 2016

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The clinical significance of forkhead box protein A1 and its role in colorectal cancer

Wenqi Ma, Jue Jiang, Miao Li, Hua Wang, Hongli Zhang, Xin He, Lili Huang, Qi Zhou
Pages: 2625-2631
Published online on: 01 August 2016

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Article

Peripheral KATP activation inhibits pain sensitization induced by skin/muscle incision and retraction via the nuclear factor-κB/c-Jun N-terminal kinase signaling pathway

Li‑Ping Qian, Shi‑Ren Shen, Jun‑Jie Chen, Lu‑Lu Ji, Su Cao
Pages: 2632-2638
Published online on: 27 July 2016

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Article

Identification of a PTPN11 hot spot mutation in a child with atypical LEOPARD syndrome

Jia Zhang, Jinwen Shen, Ruhong Cheng, Cheng Ni, Jianying Liang, Ming Li, Zhirong Yao
Pages: 2639-2643
Published online on: 27 July 2016

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Article

Vitamin D induces autophagy of pancreatic β-cells and enhances insulin secretion

Yubin Wang, Dawei He, Chengpei Ni, Huiying Zhou, Shuyan Wu, Zhimou Xue, Zhengyu Zhou
Pages: 2644-2650
Published online on: 19 July 2016

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Article

MicroRNA-101 inhibits the proliferation and invasion of bladder cancer cells via targeting c-FOS Retraction in /10.3892/mmr.2022.12643

Yongqi Long, Zhiping Wu, Xinhua Yang, Lei Chen, Zhijun Han, Yulong Zhang, Jinge Liu, Wenjin Liu, Xinyi Liu
Pages: 2651-2656
Published online on: 20 July 2016

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Article

MicroRNA-610 is downregulated in glioma cells, and inhibits proliferation and motility by directly targeting MDM2

Yu Yan, Yong Peng, Yangzhu Ou, Yugang Jiang
Pages: 2657-2664
Published online on: 27 July 2016

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Wtip is required for proepicardial organ specification and cardiac left/right asymmetry in zebrafish

Rebecca Powell, Ekaterina Bubenshchikova, Yayoi Fukuyo, Chaonan Hsu, Olga Lakiza, Hiroki Nomura, Erin Renfrew, Deborah Garrity, Tomoko Obara
Pages: 2665-2678
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Article

Combined therapeutic effects of bortezomib and anacardic acid on multiple myeloma cells via activation of the endoplasmic reticulum stress response

Xiaoxian Dong, Yuning Liao, Ningning Liu, Xianliang Hua, Jianyu Cai, Jinbao Liu, Hongbiao Huang
Pages: 2679-2684
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Article

Resveratrol inhibits phosphorylation within the signal transduction and activator of transcription 3 signaling pathway by activating sirtuin 1 in SW1353 chondrosarcoma cells

Haidong Jin, Hui Chen, Kehe Yu, Jingdong Zhang, Bin Li, Ningyu Cai, Jun Pan
Pages: 2685-2690
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Article

In vitro and in vivo anti-Vibrio vulnificus activity of psammaplin A, a natural marine compound

Byung Cheol Lee, Arim Lee, Jee Hyung Jung, Sang Ho Choi, Tae Sung Kim
Pages: 2691-2696
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Article

Astaxanthin blocks preeclampsia progression by suppressing oxidative stress and inflammation

Rong‑Rong Xuan, Ting‑Ting Niu, Hai‑Min Chen
Pages: 2697-2704
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Article

CIP2A regulates proliferation and apoptosis of multiple myeloma cells

Zhuanzhen Zheng, Zhenhua Qiao, Wenliang Chen, Rong Gong, Yalin Wang, Lianrong Xu, Yanping Ma, Li Zhang, Yujin Lu, Bo Jiang, Guoxia Li, Chunxia Dong
Pages: 2705-2709
Published online on: 27 July 2016

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Case Report

Mild Camurati‑Engelamann disease presenting with exophthalmos as the first and only manifestation: A case report

Ruizhi Jiajue, Bo Wu, Yan Jiang, Ou Wang, Mei Li, Xiaoping Xing, Weibo Xia
Pages: 2710-2716
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Article

Umbilical cord-derived mesenchymal stem cells inhibit growth and promote apoptosis of HepG2 cells

Ying‑Mei Tang, Wei‑Min Bao, Jin‑Hui Yang, Lin‑Kun Ma, Jing Yang, Ying Xu, Li‑Hong Yang, Feng Sha, Zhi‑Yuan Xu, Hua‑Mei Wu, Wei Zhou, Yan Li, Yu‑Hua Li
Pages: 2717-2724
Published online on: 21 July 2016

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Article

Functional study of the upregulation of miRNA-27a and miRNA-27b in 3T3-L1 cells in response to berberine

Yue‑Yue Wu, Xin‑Mei Huang, Jun Liu, Ying Cha, Zao‑Ping Chen, Fang Wang, Jiong Xu, Li Sheng, He‑Yuang Ding
Pages: 2725-2731
Published online on: 25 July 2016

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Article

Elevated DRD4 promoter methylation increases the risk of Alzheimer's disease in males

Huihui Ji, Yunliang Wang, Danjie Jiang, Guili Liu, Xuting Xu, Dongjun Dai, Xiaohui Zhou, Wei Cui, Jinfeng Li, Zhongming Chen, Ying Li, Dongsheng Zhou, Qin Zha, Renjie Zhuo, Liting Jiang, Yu Liu, Lili Shen, Beibei Zhang, Lei Xu, Haochang Hu, Yuzheng Zhang, Honglei Yin, Shiwei Duan, Qinwen Wang
Pages: 2732-2738
Published online on: 27 July 2016

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Article

Hypermethylation of CDH13, DKK3 and FOXL2 promoters and the expression of EZH2 in ovary granulosa cell tumors

Yanmei Xu, Xia Li, Hongtao Wang, Pengmu Xie, Xun Yan, Yu Bai, Tingguo Zhang
Pages: 2739-2745
Published online on: 18 July 2016

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Article

Immunomodulatory effects of Longdan Xiegan Tang on CD4+/CD8+ T cells and associated inflammatory cytokines in rats with experimental autoimmune uveitis

Kai Tang, Dadong Guo, Lian Zhang, Junguo Guo, Fengming Zheng, Junkang Si, Hongsheng Bi
Pages: 2746-2754
Published online on: 27 July 2016

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Article

Modulatory effects of levamisole and garlic oil on the immune response of Wistar rats: Biochemical, immunohistochemical, molecular and immunological study

Essam Hassan Mohamed, Ahmed Abdel‑Aziz Baiomy, Zein Shaban Ibrahim, Mohamed Mohamed Soliman
Pages: 2755-2763
Published online on: 27 July 2016

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Article

Protective effects of ghrelin against oxidative stress, inducible nitric oxide synthase and inflammation in a mouse model of myocardial ischemia/reperfusion injury via the HMGB1 and TLR4/NF-κB pathway

Ning Sun, Hui Wang, Lin Wang
Pages: 2764-2770
Published online on: 20 July 2016

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Article

The pro-oxidant gene p66shc increases nicotine exposure-induced lipotoxic oxidative stress in renal proximal tubule cells

Istvan Arany, Samuel Hall, Dustin K. Reed, Mehul Dixit
Pages: 2771-2777
Published online on: 25 July 2016

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Article

Neuroprotective effect of ginsenoside Rg1 prevents cognitive impairment induced by isoflurane anesthesia in aged rats via antioxidant, anti-inflammatory and anti-apoptotic effects mediated by the PI3K/AKT/GSK-3β pathway

Yini Zhang, Zhao Zhang, Haitang Wang, Nan Cai, Shuang Zhou, Yaoping Zhao, Xue Chen, Shaoqiang Zheng, Qi Si, Wei Zhang
Pages: 2778-2784
Published online on: 27 July 2016

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Article

Synergy between von Hippel-Lindau and P53 contributes to chemosensitivity of clear cell renal cell carcinoma

Ziyi Zhao, Changjin Chen, Junzhi Lin, Wentong Zeng, Juan Zhao, Yindan Liang, Qinrui Tan, Chao Yang, Hui Li
Pages: 2785-2790
Published online on: 27 July 2016

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Article

Atorvastatin ameliorates endothelium-specific insulin resistance induced by high glucose combined with high insulin

Ou Yang, Jinliang Li, Haiyan Chen, Jie Li, Jian Kong
Pages: 2791-2798
Published online on: 27 July 2016

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Article

Celastrol inhibits IL-1β-induced inflammation in orbital fibroblasts through the suppression of NF-κB activity

Hong Li, Yifei Yuan, Yali Zhang, Qianwen He, Rongjuan Xu, Fangfang Ge, Chen Wu
Pages: 2799-2806
Published online on: 28 July 2016

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Article

Prenatal valproate treatment produces autistic-like behavior and increases metabotropic glutamate receptor 1A-immunoreactivity in the hippocampus of juvenile rats

Francisco Peralta, Constanza Fuentealba, Jenny Fiedler, Esteban Aliaga
Pages: 2807-2814
Published online on: 18 July 2016

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Article

Expression of interferon regulatory factor 5 is regulated by the Sp1 transcription factor

Jin Shu, Xiao‑Hua Wang, Lan‑Bo Zhou, Chun‑Ming Jiang, Wei‑Xia Yang, Rui Jin, Lu‑Lu Wang, Guo‑Ping Zhou
Pages: 2815-2822
Published online on: 27 July 2016

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Article

Identifying the role of Wilms tumor 1 associated protein in cancer prediction using integrative genomic analyses

Li‑Sheng Wu, Jia‑Yi Qian, Minghai Wang, Haiwei Yang
Pages: 2823-2831
Published online on: 18 July 2016

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Article

Effect of evodiamine on the proliferation and apoptosis of A549 human lung cancer cells

Li Lin, Li Ren, Liujing Wen, Yu Wang, Jin Qi
Pages: 2832-2838
Published online on: 29 July 2016

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Article

Photoprotective properties of 20(S)-protopanaxatriol, an aglycone of ginseng saponins: Protection from ultraviolet-B radiation-induced oxidative stress in human epidermal keratinocytes

Sun‑Joo Oh, Kyunghoon Kim, Chang‑Jin Lim
Pages: 2839-2845
Published online on: 01 August 2016

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Article

Downregulation of AATK mediates microRNA-558-induced resistance of A549 cells to radiotherapy

Rui‑Xia Zhu, Chun‑Hui Song, Jin‑Shan Yang, Qing‑Ting Yi, Bao‑Jian Li, Si‑Hai Liu
Pages: 2846-2852
Published online on: 01 August 2016

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Article

Nitidine chloride inhibits proliferation, induces apoptosis via the Akt pathway and exhibits a synergistic effect with doxorubicin in ovarian cancer cells

Feng Ding, Tianfeng Liu, Nina Yu, Shihong Li, Xiaofei Zhang, Guanghong Zheng, Chunming Lv, Kai Mou, Jia Xu, Bo Li, Surong Wang, Haibo Song
Pages: 2853-2859
Published online on: 29 July 2016

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Article

MicroRNA-26a protects against cardiac hypertrophy via inhibiting GATA4 in rat model and cultured cardiomyocytes

Yan Liu, Zhiqian Wang, Wenliang Xiao
Pages: 2860-2866
Published online on: 28 July 2016

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Article

miR-22-5p revealed as a potential biomarker involved in the acute phase of myocardial infarction via profiling of circulating microRNAs

Agata Maciejak, Marek Kiliszek, Grzegorz Opolski, Agnieszka Segiet, Krzysztof Matlak, Slawomir Dobrzycki, Dorota Tulacz, Grazyna Sygitowicz, Beata Burzynska, Monika Gora
Pages: 2867-2875
Published online on: 27 July 2016

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Impact Factor: 5.0

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CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

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Article Open Access

Regulatory function of ten‑eleven translocation‑2 in transcriptional mechanisms of demethylated myeloma cells

Lenka Slavickova, Michaela Nemcova, Dominika Svehlova, Veronika Frybortova, Jirina Manakova, Eva Kriegova, Jiri Minarik, Katerina Smesny Trtkova
Article Number: 237
Published online on: 25 June 2026

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Mulberroside A attenuates H2O2‑induced oxidative stress and barrier dysfunction in Caco‑2 cells through Nrf2/HO‑1‑associated antioxidant signaling

Jianxin Chen, Xiufeng Huang, Xi Chen, Wenhai Jin, Dawei Lin
Article Number: 236
Published online on: 25 June 2026

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[Retracted] Puerarin promotes DUSP1 expression by regulating miR‑133a‑3p in breast cancer

Zhifeng Li, Weiwei Xu, Xiaoyan Ren, Jinhua Xu, Jianxin Chen
Article Number: 235
Published online on: 23 June 2026

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Sulforaphane attenuates cisplatin‑induced acute kidney injury by inhibiting oxidative stress, inflammation and apoptosis via regulation of NRF2

Zeyu Wu, Mengting Lu, Lei Xu, Ming Luo, Limei Shan, Hongxia Xing, Wenwen Li, Junling Qian
Article Number: 234
Published online on: 19 June 2026

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Effects of β‑hydroxybutyrate on restoring autophagic flux and mitochondrial function in macrophages exposed to oxidized low‑density lipoprotein

Weiguang Luo, Mei He, Huiling Wang
Article Number: 233
Published online on: 19 June 2026

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Review Open Access

Genetic and molecular mechanisms of hereditary thoracic aortic aneurysm and dissection (Review)

Xiaokang Wang, Qiwen Tan, Jingcheng Xu, Yunlin Yang, Haoyue Huang, Xiaomei Teng, Weihua Wu
Article Number: 232
Published online on: 18 June 2026

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Degraded sulfated galactan derived from Gracilaria fisheri induces immunogenic cell death in MDA‑MB‑231 cells

Tawut Rudtanatip, Yada Polsan, Waraporn Sakaew, Somsuda Somintara, Jenjiralai Phanphak, Jamal El‑Abid, Kanokpan Wongprasert, Choowadee Pariwatthanakun
Article Number: 231
Published online on: 17 June 2026

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Article

Irbesartan ameliorates high‑glucose‑induced epithelial‑mesenchymal transition by downregulating the expression of NLRP3 in HK‑2 cells

Qing Deng, Xiujuan Liu, Dan Wen, Yuhua Cheng, Qing Zhao, Yu Wang, Yu Xiang, Qinkai Chen, Jinlei Lv
Article Number: 230
Published online on: 17 June 2026

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A β‑1,3‑1,6‑glucan from Aureobasidium pullulans enhances apoptotic and autophagic pathways in colorectal cancer cells

Ji-Won Park, Gyeong Mim Mun, Tae Min Jo, Ji A Shin, Takao Kuge, Hisashi Kimoto, Jin-Kyung Kim
Article Number: 229
Published online on: 16 June 2026

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Growth pattern and molecular biological analysis of primary meningioma cell cultures under different conditions

Stefan Linsler, Anna-Lena Moroldo, Walter Schulz‑Schaeffer, Ralf Ketter, Joachim Oertel, Steffi Urbschat
Article Number: 228
Published online on: 12 June 2026

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Melatonin alleviates mitochondrial damage by regulating SIRT3‑mediated mitochondrial dynamics in granulosa cells under PCOS‑like conditions

Congcong Xie, Zehao Liu, Tong Chen, Hui Lu, Xiujia Zhang, Wenbo Yu, Jiaxin Zhang, Dandan Shang, Xueying Wang
Article Number: 227
Published online on: 11 June 2026

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Strontium‑based metal‑organic framework/alendronate‑silk fibroin hydrogels promote tendon‑bone interface healing

Tao Yang, Hanji Zhang, Mingjun Li, Yiming Ren, Yunbo Sun, Weiyu Hou, Mengqiang Tian
Article Number: 226
Published online on: 11 June 2026

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[Retracted] Tripterygium glycoside suppresses epithelial‑to‑­­ mesenchymal transition of diabetic kidney disease podocytes by targeting autophagy through the mTOR/Twist1 pathway

Mei Tao, Danna Zheng, Xudong Liang, Diandian Wu, Kang Hu, Juan Jin, Qiang He
Article Number: 225
Published online on: 08 June 2026

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Gut microbiota‑derived metabolites in cardiovascular disease: Focus on trimethylamine N‑oxide, short‑chain fatty acids and bile acids (Review)

Meizhu Gao, Zhenming Hao, Yiling Li, Weixue Liu, Fubao Zhang
Article Number: 224
Published online on: 08 June 2026

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Fucoxanthin alleviates chondrocyte inflammation and osteoarthritis by modulating the JAK2/STAT3 signaling pathway

Miradj Siddick Adam, Huangming Zhuang, Xunshan Ren, Yuelong Zhang, Panghu Zhou
Article Number: 223
Published online on: 08 June 2026

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Prediction of molecular targets for zedoary turmeric oil in inhibiting proliferation and inducing apoptosis in non‑small cell lung cancer

Huaiyong Li, Lili Liu, Qingzhu Yang, Yao Li, Yongli Song, Jing Jiang, Zhenzhong Wu, Weiwei Zhang, Baisong Lou
Article Number: 222
Published online on: 08 June 2026

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Molecular mechanisms of iron metabolism and ferroptosis in cardiovascular diseases and intervention strategies targeting natural products (Review)

Liangqing Ge, Tianqing Zhang, Jiangbiao Yu, Sijie Xiao, Yu Zhou, Li Luo
Article Number: 221
Published online on: 05 June 2026

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Correction Open Access

[Corrigendum] Electroacupuncture at GV20‑GB7 regulates mitophagy to protect against neurological deficits following intracerebral hemorrhage via inhibition of apoptosis

Ruiqiao Guan, Zhihao Li, Xiaohong Dai, Wei Zou, Xueping Yu, Hao Liu, Qiuxin Chen, Wei Teng, Peng Liu, Xiaoying Liu, Shanshan Dong
Article Number: 220
Published online on: 03 June 2026

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Article Open Access

LINC01117 promotes the malignant proliferation of lung adenocarcinoma by increasing HOXD8 mRNA stability

Lizhong Zeng, Jie Shi, Cai Zhang, Yujiao Dong, Yang Chen, Qiuhong Zhang, Long Zhang, Shuanying Yang
Article Number: 219
Published online on: 03 June 2026

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Review Open Access

Targeting regulatory T cells in the prostate cancer microenvironment: From mechanisms to therapeutics (Review)

Hua Luo
Article Number: 218
Published online on: 03 June 2026

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Article Open Access

Dapagliflozin alleviates heart failure with preserved ejection fraction potentially by regulating the AIM2/caspase‑1/GSDMD pathway and attenuating pyroptosis

Sailiang Ding, Hao Yang, Ting Lu, Yibin Luo, Liang Xu, Xianghui Zeng
Article Number: 217
Published online on: 03 June 2026

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Retraction Open Access

[Retracted] Carnosic acid alleviates brain injury through NF‑κB‑regulated inflammation and Caspase‑3‑associated apoptosis in high fat‑induced mouse models

Yong Liu, Yan Zhang, Ming Hu, Yu-Hu Li, Xing-Hua Cao
Article Number: 216
Published online on: 02 June 2026

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Review Open Access

SIRT1/AMPK/PGC1α pathway in ischemic stroke: Elucidating neuroprotective strategies (Review)

Irum Naz Abbasi, Nashwa Amin, Qiaolu Xu, Azhar Badry Hussain, Fei Wu, Xia Yuan, Yang Yang, Suhong Ye, Marong Fang, Yihua Jiang
Article Number: 215
Published online on: 02 June 2026

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Review Open Access

Beyond the primary site: Molecular insights and clinical implications of cancer metastatic overlap between lung and urological organ cancers (Review)

Yinhuan Wang, Jiefang Guan
Article Number: 214
Published online on: 29 May 2026

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September-2026 Volume 34 Issue 3

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Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

Sedanolide alleviates LPS‑induced depressive‑like behaviors by modulating the C3a/C3aR signaling axis and microglial glycolysis

Shaocong Lu, Fangla Luo, Niqi Chen, Gongde Shi, Yeru Chen
Article Number: 257
Published online on: 16 July 2026

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Expression of Concern Open Access

[Expression of Concern] Chrysophanol inhibits proliferation and induces apoptosis through NF‑κB/cyclin D1 and NF‑κB/Bcl‑2 signaling cascade in breast cancer cell lines

Li Ren, Zhouping Li, Chunmei Dai, Danyu Zhao, Yanjie Wang, Chunyu Ma, Chun Liu
Article Number: 256
Published online on: 15 July 2026

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Article Open Access

PCSK9 alleviates doxorubicin‑induced pyroptosis of cardiomyocytes

Chaochu Cui, Jinyu Zhao, Xiaoqian Li, Shengming Huang, Gang Liu, Xinhui Xu, Can Guo, Tiesuo Zhao, Jiang Du, Shipeng Li, Xianwei Wang, Jianbo Yang
Article Number: 255
Published online on: 14 July 2026

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Review Open Access

From cell to disease: Regulatory networks and mechanisms of super‑enhancers in aging (Review)

Xiaodan Wang, Weiqian Deng, Shuangxi Tu, Haojun Tang, Kai Yin, Xiao Zhu
Article Number: 254
Published online on: 14 July 2026

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Retraction Open Access

[Retracted] Matrine‑induced apoptosis in Hep3B cells via the inhibition of MDM2

Ning Zhou, Jiequn Li, Ting Li, Guangshun Chen, Zhongqiang Zhang, Zhongzhou Si
Article Number: 253
Published online on: 13 July 2026

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Review Open Access

Role of PANoptosis in the development of gastric immunity and related gastric mucosal disease (Review)

Lan Wang, Zhiyuan Ma, Bei Ji, Shuhui Liu, Shuji Terai, Biguang Tuo, Taolang Li, Xuemei Liu
Article Number: 252
Published online on: 09 July 2026

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Article

Leonurine inhibits the proliferation and metastasis of liver cancer cells by regulating the PI3K/AKT signaling pathway via epithelial‑mesenchymal transition

Bowen Hu, Maher Al Hussan, Jiakai Zhang, Peihao Wen, Changjun Huang, Yang Chen, Huanfei Ding
Article Number: 251
Published online on: 08 July 2026

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Correction Open Access

[Corrigendum] Resistin aggravates the expression of proinflammatory cytokines in cerulein‑stimulated AR42J pancreatic acinar cells

Chong-Yi Jiang, Wei Wang
Article Number: 250
Published online on: 08 July 2026

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Review Open Access

A‑Raf: A serine/threonine protein kinase with important biological functions (Review)

Muhan Yang, Mengying Chen, Jinmei Wei, Yanling Li, Chen Long, Yan Lei, Yanhong Zhou
Article Number: 249
Published online on: 07 July 2026

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Review Open Access

Gut dysbiosis‑derived butyrate loss predicts feeding intolerance: Multiomics evidence guiding nurse‑driven microbiota‑supportive interventions (Review)

Ling Wei, Xiaohua Kong, Yuying Li, Huixia Wu, Yirong Gan, Fang Sun
Article Number: 248
Published online on: 07 July 2026

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Retraction Open Access

[Retracted] Network pharmacology combined with experimental validation to investigate the effect of Rongjin Niantong Fang on chondrocyte apoptosis in knee osteoarthritis

Jun Chen, Ting Zhang, Qingqing Luo, Ruyi Wang, Yuting Dai, Zhenyuan Chen, Chutian Zhang, Xuzheng Chen, Guangwen Wu
Article Number: 247
Published online on: 06 July 2026

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Article Open Access

Laggera alata attenuates LPS‑induced systemic inflammation and hepatic‑pulmonary injury by regulating PINK1/Parkin-associated mitophagy and macrophage polarization

Jiangcun Wei, Wen Zhong, Guangyun Zhou, Mingtao Huang, Xiaodong Huang, Jing Liang
Article Number: 246
Published online on: 02 July 2026

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Review Open Access

Proteolysis‑targeting chimeras in oral squamous cell carcinoma: Current evidence, translational challenges and future directions (Review)

Yun Bai, Danhua Ma, Xi Yang, Min Wang
Article Number: 245
Published online on: 02 July 2026

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Review Open Access

Evolving role of biomarkers beyond prostate‑specific antigen in refining prostate cancer screening: From blood‑based tests to urinary and genetic markers (Review)

Luxi Li, Linyue Zhang, Zehong Li, Keqiang Chai, Weidong Ren
Article Number: 244
Published online on: 02 July 2026

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Article Open Access

Nanocurcumin attenuates brain injury in rats with desert dry‑heat‑induced exertional heat stroke by suppressing TLR4/MyD88/NF‑κB signaling

Lisong Su, Jinquan Qu, Jiajia Li, Wenhui Shi, Laiyang Song, Feixing Liang, Jiangwei Liu
Article Number: 243
Published online on: 02 July 2026

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Review Open Access

TREM2 in glioma: Reprogramming the immune microenvironment from mechanistic understanding to clinical translation (Review)

Junqi Fan, Hongyan Shen, Dan Liu, Songbai Luo, Qingqing Huang, Yi Wen, Libang Yuan
Article Number: 242
Published online on: 02 July 2026

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Article Open Access

Human parvovirus B19 VP1u‑induced osteoclastogenesis is enhanced by RANKL in RAW264.7 macrophage cells

Chun-Yu Lin, Bor-Show Tzang, Yi-Hsuan Lin, Chih-Chen Tzang, Tsai-Ching Hsu
Article Number: 241
Published online on: 30 June 2026

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Retraction Open Access

[Retracted] Anti‑tumor peptide AP25 decreases cyclin D1 expression and inhibits MGC‑803 proliferation via phospho­extracellular signal‑regulated kinase‑, Src‑, c‑Jun N‑terminal kinase‑ and phosphoinositide 3­-kinase‑associated pathways  

Jialiang Hu, Tao Cheng, Lijun Zhang, Beicheng Sun, Lei Deng, Hanmei Xu
Article Number: 240
Published online on: 29 June 2026

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Article Open Access

Aspirin prevents postoperative peritoneal adhesions by inhibiting the TGF‑β1/Smad signaling pathway in rats

Siqi Yan, Yuan Ren, Bingyan Liu, Pai Xiong, Yimin Sun
Article Number: 239
Published online on: 29 June 2026

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Article Open Access

Morinda officinalis oligosaccharides ameliorate corticosterone‑induced depression‑like behaviour in mice by modulating the BDNF signalling pathway and gut microbiota

Mengjie He, Zixuan Liu, Yuxin Chen, Xiaoru Wu, Xueling Dai, Qian Liu, Shuo Wang, Zeping Zuo, Yaxuan Sun
Article Number: 238
Published online on: 29 June 2026

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