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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
April-2016 Volume 35 Issue 4

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

Enabling personalized cancer medicine decisions: The challenging pharmacological approach of PBPK models for nanomedicine and pharmacogenomics (Review)

Ioannis S. Vizirianakis, George A. Mystridis, Konstantinos Avgoustakis, Dimitrios G. Fatouros, Marios Spanakis
Pages: 1891-1904
Published online on: 18 January 2016

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Review

Real-time RT-PCR systems for CTC detection from blood samples of breast cancer and gynaecological tumour patients (Review)

Ulrich Andergassen, Alexandra C. Kölbl, Sven Mahner, Udo Jeschke
Pages: 1905-1915
Published online on: 02 February 2016

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Article

Long non-coding RNA BACE1-AS is a novel target for anisomycin-mediated suppression of ovarian cancer stem cell proliferation and invasion

Qing Chen, Xinghui Liu, Limin Xu, Ying Wang, Suwei Wang, Qiong Li, Yongyi Huang, Te Liu
Pages: 1916-1924
Published online on: 18 January 2016

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Article Open Access

Radiation enhances the therapeutic effect of Banoxantrone in hypoxic tumour cells with elevated levels of nitric oxide synthase

Manal Mehibel, Simendra Singh, Rachel L. Cowen, Kaye J. Williams, Ian J. Stratford
Pages: 1925-1932
Published online on: 13 January 2016

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Article Open Access

siRNA-induced TRAF6 knockdown promotes the apoptosis and inhibits the invasion of human lung cancer SPC-A1 cells

Zhiyong He, Chuanzhong Huang, Gen Lin, Yunbin Ye
Pages: 1933-1940
Published online on: 01 February 2016

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Article Open Access

Emodin enhances the demethylation by 5-Aza-CdR of pancreatic cancer cell tumor-suppressor genes P16, RASSF1A and ppENK

Feng-Ping Pan, Hong-Kun Zhou, He-Qi Bu, Zi-Qiang Chen, Hao Zhang, Lu-Ping Xu, Jian Tang, Qing-Jiang Yu, Yong-Quan Chu, Jie Pan, Yong Fei, Sheng-Zhang Lin, Dian-Lei Liu, Liang Chen
Pages: 1941-1949
Published online on: 13 January 2016

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Article Open Access

miRNA-10b sponge: An anti-breast cancer study in vitro

Ai-Ling Liang, Ting-Ting Zhang, Ning Zhou, Cui Yun Wu, Man-Hua Lin, Yong-Jun Liu
Pages: 1950-1958
Published online on: 26 January 2016

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Article

Induction of eEF2-specific antitumor CTL responses in vivo by vaccination with eEF2-derived 9mer-peptides

Hiroko Nakajima, Yui Murakami, Eiichi Morii, Toshiki Akao, Naoya Tatsumi, Satoko Odajima, Mari Fukuda, Takao Machitani, Miki Iwai, Sayo Kawata, Nozomi Hojo, Yoshihiro Oka, Haruo Sugiyama, Yusuke Oji
Pages: 1959-1966
Published online on: 22 January 2016

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Article

Oncogenic cAMP responsive element binding protein 1 is overexpressed upon loss of tumor suppressive miR-10b-5p and miR-363-3p in renal cancer

Yifan Li, Duqun Chen, Yuchi Li, Lu Jin, Jiaju Liu, Zhengming Su, Zhengyu Qi, Min Shi, Zhimao Jiang, Liangchao Ni, Shangqi Yang, Yaoting Gui, Xiangming Mao, Yun Chen, Yongqing Lai
Pages: 1967-1978
Published online on: 20 January 2016

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Article

Expression of MAGE-A1-A12 subgroups in the invasive tumor front and tumor center in oral squamous cell carcinoma

M. Brisam, S. Rauthe, S. Hartmann, C. Linz, R. C. Brands, A. C. Kübler, A. Rosenwald, U. D. Müller-Richter
Pages: 1979-1986
Published online on: 28 January 2016

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Article

Constitutive expression and anticancer potency of a novel immunotoxin onconase-DV3

Miaonan Sun, Huichun Tang, Yan Gao, Xinxuan Dai, Yue Yuan, Chunmei Zhang, Dejun Sun
Pages: 1987-1994
Published online on: 18 January 2016

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Article

Imperatorin exhibits anticancer activities in human colon cancer cells via the caspase cascade

Yi Mei Zheng, Amy Xiaoxu Lu, James Zheng Shen, Amy Ho Yan Kwok, Wing Shing Ho
Pages: 1995-2002
Published online on: 21 January 2016

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Article

SEPT7 overexpression inhibits glioma cell migration by targeting the actin cytoskeleton pathway

Mingshan Hou, Xiaobing Liu, Jie Cao, Bo Chen
Pages: 2003-2010
Published online on: 03 February 2016

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Article

HOXB13-mediated suppression of p21WAF1/CIP1 regulates JNK/c-Jun signaling in prostate cancer cells

Young-Rang Kim, Taek Won Kang, Phuong Kim To, Nguyen Thi Xuan Nguyen, Young Seok Cho, Chaeyong Jung, Min Soo Kim
Pages: 2011-2016
Published online on: 15 January 2016

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Article

MicroRNA-365a-3p promotes tumor growth and metastasis in laryngeal squamous cell carcinoma

Jiangqiao Geng, Yuanhu Liu, Yaqiong Jin, Jun Tai, Jie Zhang, Xiao Xiao, Ping Chu, Yongbo Yu, Sheng Cai Wang, Jie Lu, Shujing Han, Jin Shi, Yongli Guo, Xin Ni
Pages: 2017-2026
Published online on: 11 February 2016

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Article

Emodin inhibits epithelial to mesenchymal transition in epithelial ovarian cancer cells by regulation of GSK-3β/β-catenin/ZEB1 signaling pathway

Chen Hu, Taotao Dong, Rui Li, Jingjing Lu, Xuan Wei, Peishu Liu
Pages: 2027-2034
Published online on: 25 January 2016

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Article

Expression profile of long non-coding RNAs in colorectal cancer: A microarray analysis

Jia Luo, Luning Xu, Yigui Jiang, Dexiang Zhuo, Shengjun Zhang, Lianhui Wu, Huadong Xu, Yue Huang
Pages: 2035-2044
Published online on: 01 February 2016

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Article

Kamebakaurin inhibits the expression of hypoxia-inducible factor-1α and its target genes to confer antitumor activity

Ke Si Wang, Juan Ma, Chunliu Mi, Jing Li, Jung Joon Lee, Xuejun Jin
Pages: 2045-2052
Published online on: 19 January 2016

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Article

Activation of NLRP3 inflammasome enhances the proliferation and migration of A549 lung cancer cells

Yanli Wang, Hui Kong, Xiaoning Zeng, Wenrui Liu, Zailiang Wang, Xiaopei Yan, Hong Wang, Weiping Xie
Pages: 2053-2064
Published online on: 18 January 2016

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Article

Xanthohumol inhibits STAT3 activation pathway leading to growth suppression and apoptosis induction in human cholangiocarcinoma cells

Hasaya Dokduang, Puangrat Yongvanit, Nisana Namwat, Chawalit Pairojkul, Sakkarn Sangkhamanon, Mika Sakurai Yageta, Yoshinori Murakami, Watcharin Loilome
Pages: 2065-2072
Published online on: 21 January 2016

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Article

Clinical and biological significance of transcription termination factor, RNA polymerase I in human liver hepatocellular carcinoma

Hisateru Komatsu, Tomohiro Iguchi, Masami Ueda, Sho Nambara, Tomoko Saito, Hidenari Hirata, Shotaro Sakimura, Yuki Takano, Ryutaro Uchi, Yoshiaki Shinden, Hidetoshi Eguchi, Takaaki Masuda, Keishi Sugimachi, Hidetoshi Eguchi, Yuichiro Doki, Masaki Mori, Koshi Mimori
Pages: 2073-2080
Published online on: 25 January 2016

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Article

YL4073 is a potent autophagy-stimulating antitumor agent in an in vivo model of Lewis lung carcinoma

You-Zhi Xu, Yong-Huai Li, Wen-Jie Lu, Kun Lu, Chun-Ting Wang, Yan Li, Hong-Jun Lin, Li-Xin Kan, Sheng-Yong Yang, Si-Ying Wang, Ying-Lan Zhao
Pages: 2081-2088
Published online on: 01 February 2016

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Article

Benzyl isothiocyanate alters the gene expression with cell cycle regulation and cell death in human brain glioblastoma GBM 8401 cells

Nou-Ying Tang, Fu-Shin Chueh, Chien-Chih Yu, Ching-Lung Liao, Jen-Jyh Lin, Te-Chun Hsia, King-Chuen Wu, Hsin-Chung Liu, Kung-Wen Lu, Jing-Gung Chung
Pages: 2089-2096
Published online on: 19 January 2016

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Article

Novel, isoform-selective, cholecystokinin A receptor antagonist inhibits colon and pancreatic cancers in preclinical models through novel mechanism of action

Suriyan Ponnusamy, Eric Lattmann, Pornthip Lattmann, Thirumagal Thiyagarajan, Balaram N. Padinjarethalakal, Ramesh Narayanan
Pages: 2097-2106
Published online on: 22 January 2016

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Article

The tumor suppressor role of miR-4782-3p in hepatocellular carcinoma

Wentao Bo, Yong Hu, Xielin Feng, Hui Zhang, Lang Tian, Aixiang Liu
Pages: 2107-2112
Published online on: 18 January 2016

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Article

Inhibition of mitogen-activated protein kinase signaling pathway sensitizes breast cancer cells to endoplasmic reticulum stress-induced apoptosis

Fen Yang, Xiao Yan Tang, Hao Liu, Zhi Wen Jiang
Pages: 2113-2120
Published online on: 20 January 2016

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Article

Ubenimex inhibits cell proliferation, migration and invasion by inhibiting the expression of APN and inducing autophagic cell death in prostate cancer cells

Xiaoqing Wang, Zhihong Niu, Yang Jia, Meng Cui, Liping Han, Yongfei Zhang, Zheng Liu, Dongbin Bi, Shuai Liu
Pages: 2121-2130
Published online on: 03 February 2016

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Article

ST6GalNAcII mediates tumor invasion through PI3K/Akt/NF-κB signaling pathway in follicular thyroid carcinoma

Xiaolong Miao, Yongfu Zhao
Pages: 2131-2140
Published online on: 22 January 2016

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Article

Aberrant expression of Golgi protein 73 is indicative of a poor outcome in hepatocellular carcinoma

Kai Jiang, Wei Li, Shuxin Shang, Lu Sun, Kun Guo, Shu Zhang, Yinkun Liu
Pages: 2141-2150
Published online on: 28 January 2016

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Article

miR-137 acts as a tumor suppressor in papillary thyroid carcinoma by targeting CXCL12 Retraction in /10.3892/or.2021.8157

Su Dong, Meishan Jin, Ye Li, Peiyou Ren, Jia Liu
Pages: 2151-2158
Published online on: 01 February 2016

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Article

Gene expression of membrane transporters: Importance for prognosis and progression of ovarian carcinoma

Katerina Elsnerova, Beatrice Mohelnikova-Duchonova, Ela Cerovska, Marie Ehrlichova, Ivan Gut, Lukas Rob, Petr Skapa, Martin Hruda, Alena Bartakova, Jiri Bouda, Pavel Vodicka, Pavel Soucek, Radka Vaclavikova
Pages: 2159-2170
Published online on: 28 January 2016

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Article

Identification of miRNAs and differentially expressed genes in early phase non-small cell lung cancer

Wen Tian, Jie Liu, Baojing Pei, Xiaobo Wang, Yu Guo, Lin Yuan
Pages: 2171-2176
Published online on: 14 January 2016

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Article

Genomic profiling of a combined large cell neuroendocrine carcinoma of the submandibular gland

Simon Andreasen, Marta Persson, Katalin Kiss, Preben Homøe, Steffen Heegaard, Göran Stenman
Pages: 2177-2182
Published online on: 12 February 2016

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Article

B7-H3, B7-H4, Foxp3 and IL-2 expression in cervical cancer: Associations with patient outcome and clinical significance

Chenglin Huang, Lei Zhou, Xiaohan Chang, Xiaoao Pang, Huijie Zhang, Shulan Zhang
Pages: 2183-2190
Published online on: 02 February 2016

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Article

Norcantharidin blocks Wnt/β-catenin signaling via promoter demethylation of WIF-1 in glioma

Dajiang Xie, Jixi Xie, Yingfeng Wan, Li Ma, Xuchen Qi, Kun Wang, Shuxu Yang
Pages: 2191-2197
Published online on: 14 January 2016

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Article

Co-expression of FOXL1 and PP2A inhibits proliferation inducing apoptosis in pancreatic cancer cells via promoting TRAIL and reducing phosphorylated MYC

Yunwei Li, Dongyang Yu, Weiwei Sheng, He Song, Yuji Li, Ming Dong
Pages: 2198-2206
Published online on: 25 January 2016

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Article

Chromosomal aberrations and prognosis in patients with concomitant chemoradiotherapy for resected head and neck cancer

Sung‑Won Park, Young‑Hoon Joo, Seung‑Hyun Jung, Seon‑Hee Yim, In‑Chul Nam, Kwang‑Jae Cho, Min‑Sik Kim, Yeun‑Jun Chung
Pages: 2207-2215
Published online on: 26 January 2016

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Article

MicroRNA-199a-5p inhibits VEGF-induced tumorigenesis through targeting oxidored-nitro domain-containing protein 1 in human HepG2 cells

Rong Gui, Rong Huang, Jun-Hua Zhang, Xian-Hui Wen, Xin-Min Nie
Pages: 2216-2222
Published online on: 12 January 2016

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Article

MDM2 gene amplification in esophageal carcinoma

Maike Michalk, Jeannine Meinrath, Helen Künstlinger, Ulrike Koitzsch, Uta Drebber, Sabine Merkelbach‑Bruse, Elfriede Bollschweiler, Michael Kloth, Wolfgang Hartmann, Arnulf Hölscher, Alexander Quaas, Peter P. Grimminger, Margarete Odenthal
Pages: 2223-2227
Published online on: 20 January 2016

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Article

Genome-wide DNA methylation analysis in hepatocellular carcinoma

Nobuhisa Yamada, Kohichiroh Yasui, Osamu Dohi, Yasuyuki Gen, Akira Tomie, Tomoko Kitaichi, Naoto Iwai, Hironori Mitsuyoshi, Yoshio Sumida, Michihisa Moriguchi, Kanji Yamaguchi, Taichiro Nishikawa, Atsushi Umemura, Yuji Naito, Shinji Tanaka, Shigeki Arii, Yoshito Itoh
Pages: 2228-2236
Published online on: 11 February 2016

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Article

Effects of HSP27 downregulation on PDT resistance through PDT-induced autophagy in head and neck cancer cells

Jisun Kim, Haesoon Lim, Sangwoo Kim, Hyejung Cho, Yong Kim, Xiaojie Li, Hongran Choi, Okjoon Kim
Pages: 2237-2245
Published online on: 26 January 2016

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Article

(-)-β-hydrastine suppresses the proliferation and invasion of human lung adenocarcinoma cells by inhibiting PAK4 kinase activity Retraction in /10.3892/or.2025.8892

Bingyu Guo, Xiaodong Li, Shuai Song, Meng Chen, Maosheng Cheng, Dongmei Zhao, Feng Li
Pages: 2246-2256
Published online on: 25 January 2016

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Article

A transcriptional miRNA-gene network associated with lung adenocarcinoma metastasis based on the TCGA database

Yubo Wang, Rui Han, Zhaojun Chen, Ming Fu, Jun Kang, Kunlin Li, Li Li, Hengyi Chen, Yong He
Pages: 2257-2269
Published online on: 14 January 2016

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Article

Evaluation of HO-1 expression, cellular ROS production, cellular proliferation and cellular apoptosis in human esophageal squamous cell carcinoma tumors and cell lines

Quan-Guang Ren, Sheng-Li Yang, Jian-Li Hu, Pin-Dong Li, Ye-Shan Chen, Qiu-Shuang Wang
Pages: 2270-2276
Published online on: 13 January 2016

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Article

Downregulation of IDH2 exacerbates the malignant progression of osteosarcoma cells via increased NF-κB and MMP-9 activation

Wan-Rong Yi, Zong-Huan Li, Bai-Wen Qi, Mendame Ehya Regis Ernest, Xiang Hu, Ai-Xi Yu
Pages: 2277-2285
Published online on: 13 January 2016

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Article

Unveiling a novel biomarker panel for diagnosis and classification of well-differentiated thyroid carcinomas

N. Monique Paricharttanakul, Kittirat Saharat, Daranee Chokchaichamnankit, Phaibul Punyarit, Chantragan Srisomsap, Jisnuson Svasti
Pages: 2286-2296
Published online on: 15 January 2016

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Article

Methylation and expression of miRNAs in precancerous lesions and cervical cancer with HPV16 infection

Hilda Jiménez-Wences, Dinorah Nashely Martínez-Carrillo, Oscar Peralta-Zaragoza, Gabriela Elizabeth Campos-Viguri, Daniel Hernández-Sotelo, Marco Antonio Jiménez-López, José Guadalupe Muñoz-Camacho, Víctor Hugo Garzón-Barrientos, Berenice Illades-Aguiar, Gloria Fernández-Tilapa
Pages: 2297-2305
Published online on: 21 January 2016

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Article

Silencing NACK by siRNA inhibits tumorigenesis in non-small cell lung cancer via targeting Notch1 signaling pathway

Ranran Kong, Jie Feng, Yuefeng Ma, Bin Zhou, Shaomin Li, Wei Zhang, Jiantao Jiang, Jin Zhang, Zhe Qiao, Ting Zhang, Quanjin Zang, Xijing He
Pages: 2306-2314
Published online on: 13 January 2016

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Article

RNA-binding motif protein 5 inhibits the proliferation of cigarette smoke-transformed BEAS-2B cells through cell cycle arrest and apoptosis

Xue-Jiao Lv, Yan-Wei Du, Yu-Qiu Hao, Zhen-Zhong Su, Lin Zhang, Li-Jing Zhao, Jie Zhang
Pages: 2315-2327
Published online on: 12 January 2016

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Article

3-β-Εrythrodiol isolated from Conyza canadensis inhibits MKN‑45 human gastric cancer cell proliferation by inducing apoptosis, cell cycle arrest, DNA fragmentation, ROS generation and reduces tumor weight and volume in mouse xenograft model Retraction in /10.3892/or.2021.7980

Kai Liu, Yue-Hong Qin, Jian-Yong Yu, Heng Ma, Xi-Lin Song
Pages: 2328-2338
Published online on: 03 February 2016

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Article

EGCG induces lung cancer A549 cell apoptosis by regulating Ku70 acetylation

Min Li, Jing-Jing Li, Qi-Hua Gu, Jian An, Li-Ming Cao, Hua-Ping Yang, Cheng-Ping Hu
Pages: 2339-2347
Published online on: 21 January 2016

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Article

GSK-3 inhibitor inhibits cell proliferation and induces apoptosis in human osteosarcoma cells

Hideki Nishimura, Osamu Nakamura, Yoshiki Yamagami, Masaki Mori, Ryosuke Horie, Natsuko Fukuoka, Tetsuji Yamamoto
Pages: 2348-2354
Published online on: 15 January 2016

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Article

Distinct characterization of two vinorelbine-resistant breast cancer cell lines developed by different strategies

Mingjie Xu, Donghai Jiang, Jiaying Shen, Huilin Zheng, Weimin Fan
Pages: 2355-2363
Published online on: 15 January 2016

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Article

Dracorhodin perchlorate induces the apoptosis of glioma cells Retraction in /10.3892/or.2021.8049

Xin Chen, Junjie Luo, Linghu Meng, Taifeng Pan, Binjie Zhao, Zhen-Gang Tang, Yongjian Dai
Pages: 2364-2372
Published online on: 04 February 2016

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Article

Decreased expression of the type III TGF-β receptor enhances metastasis and invasion in hepatocellullar carcinoma progression

Sen Zhang, Wu-Yi Sun, Jing-Jing Wu, Yuan-Jing Gu, Wei Wei
Pages: 2373-2381
Published online on: 08 February 2016

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BCL-3 promotes the tumor growth of hepatocellular carcinoma by regulating cell proliferation and the cell cycle through cyclin D1 Corrigendum in /10.3892/or.2022.8456

Kangsheng Tu, Zhikui Liu, Bowen Yao, Yumo Xue, Meng Xu, Changwei Dou, Guozhi Yin, Jun Wang
Pages: 2382-2390
Published online on: 11 February 2016

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Estrogen promotes fat mass and obesity-associated protein nuclear localization and enhances endometrial cancer cell proliferation via the mTOR signaling pathway

Yaping Zhu, Jiaqi Shen, Liyan Gao, Youji Feng
Pages: 2391-2397
Published online on: 05 February 2016

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MEK activity controls IL-8 expression in tamoxifen-resistant MCF-7 breast cancer cells

Sangmin Kim, Myeongjin Jeon, Jeong Eon Lee, Seok Jin Nam
Pages: 2398-2404
Published online on: 13 January 2016

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SMC1 promotes epithelial-mesenchymal transition in triple-negative breast cancer through upregulating Brachyury

Kaichun Li, Mingzhen Ying, Dan Feng, Yan Chen, Jingwen Wang, Yajie Wang
Pages: 2405-2412
Published online on: 15 January 2016

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Effects of BP-14, a novel cyclin-dependent kinase inhibitor, on anaplastic thyroid cancer cells

Lorenzo Allegri, Federica Baldan, Catia Mio, Cinzia Puppin, Diego Russo, Vladimir Kryštof, Giuseppe Damante
Pages: 2413-2418
Published online on: 05 February 2016

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Knockdown of chemokine receptor CXCR4 gene by RNA interference: Effects on the B16-F10 melanoma growth

Nayara Delgado André, Viviane Aline Oliveira Silva, Maria Angelica Ehara Watanabe, Fernando Luiz De Lucca
Pages: 2419-2424
Published online on: 12 February 2016

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MCG101-induced cancer anorexia-cachexia features altered expression of hypothalamic Nucb2 and Cartpt and increased plasma levels of cocaine- and amphetamine-regulated transcript peptides

Jonathan R. Burgos, Britt-Marie Iresjö, Ulrika Smedh
Pages: 2425-2430
Published online on: 14 January 2016

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Spheroid-based 3-dimensional culture models: Gene expression and functionality in head and neck cancer

Marianne Schmidt, Claus-Juergen Scholz, Christine Polednik, Jeanette Roller
Pages: 2431-2440
Published online on: 21 January 2016

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MicroRNA-27b suppresses Helicobacter pylori-induced gastric tumorigenesis through negatively regulating Frizzled7

Yan Geng, Xiaolan Lu, Xiaokang Wu, Li Xue, Xiangling Wang, Jiru Xu
Pages: 2441-2450
Published online on: 18 January 2016

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DNA methylation-induced E-cadherin silencing is correlated with the clinicopathological features of melanoma

Mario Venza, Maria Visalli, Teresa Catalano, Carmelo Biondo, Concetta Beninati, Diana Teti, Isabella Venza
Pages: 2451-2460
Published online on: 11 February 2016

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Cullin-5, a ubiquitin ligase scaffold protein, is significantly underexpressed in endometrial adenocarcinomas and is a target of miR-182

Eric J. Devor, Brandon M. Schickling, Henry D. Reyes, Akshaya Warrier, Brittany Lindsay, Michael J. Goodheart, Donna A. Santillan, Kimberly K. Leslie
Pages: 2461-2465
Published online on: 01 February 2016

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Knockdown of MACC1 expression increases cisplatin sensitivity in cisplatin-resistant epithelial ovarian cancer cells

Ruitao Zhang, Huirong Shi, Fang Ren, Xia Li, Minghui Zhang, Wei Feng, Yanyan Jia
Pages: 2466-2472
Published online on: 21 January 2016

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Quercetin-3-O-glucoside suppresses pancreatic cancer cell migration induced by tumor-deteriorated growth factors in vitro

Jungwhoi Lee, Jungsul Lee, Seung Jun Kim, Jae Hoon Kim
Pages: 2473-2479
Published online on: 28 January 2016

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TIPE2, a negative regulator of TLR signaling, regulates p27 through IRF4-induced signaling

Yanping Peng, Qian Zhao, Hanyu Zhang, Bo Han, Suxia Liu, Mingyong Han, Shili Liu
Pages: 2480-2486
Published online on: 14 January 2016

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Upregulation of PAWR by small activating RNAs induces cell apoptosis in human prostate cancer cells

Kai Yang, Jie Shen, Shan-Wen Chen, Jie Qin, Xiang-Yi Zheng, Li-Ping Xie
Pages: 2487-2493
Published online on: 21 January 2016

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Correction Open Access

[Corrigendum] Antitumor effects of IDN5109 on head and neck squamous cell carcinoma

Daisuke Sano, Hideki Matsuda, Yukari Ishiguro, Goshi Nishimura, Mariko Kawakami, Mamoru Tsukuda
Pages: 2494-2494
Published online on: 18 January 2016

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Correction Open Access

[Corrigendum] Antitumor effects of ZD6474 on head and neck squamous cell carcinoma

Daisuke Sano, Mariko Kawakami, Kyoko Fujita, Machiko Kimura, Yukiko Yamashita, Yukari Ishiguro, Goshi Nishimura, Hideki Matsuda, Mamoru Tsukuda
Pages: 2495-2495
Published online on: 18 January 2016

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Journal Cover
February-2026 Volume 55 Issue 2

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Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

Exploring the role of disulfidptosis‑related signatures in immune microenvironment, prognosis and therapeutic strategies of cholangiocarcinoma

Yue Chen, Jun Wu, Danxia Zhu, Lu Jiang, Jian Wang, Dachuan Zhang, Wenting He
Article Number: 37
Published online on: 02 January 2026

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Correction Open Access

[Corrigendum] Isolinderalactone enhances the inhibition of SOCS3 on STAT3 activity by decreasing miR‑30c in breast cancer

Meng-Chi Yen, Ying-Chu Shih, Ya-Ling Hsu, En-Shyh Lin, Yi-Shiuan Lin, Eing-Mei Tsai, Ya-Wen Ho, Ming-Feng Hou, Po-Lin Kuo
Article Number: 36
Published online on: 22 December 2025

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Hypoxia‑mediated Krebs von den Lungen‑6 expression in breast cancer: Implications for tumor invasion and metastasis

Taisei Ichihara, Yoshihiro Hayashi, Takuya Sato, Mitsuko Iguchi, Makoto Toi, Hironaga Satake, Ichiro Murakami
Article Number: 35
Published online on: 19 December 2025

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[Retracted] β‑elemene decreases cell invasion by upregulating E‑cadherin expression in MCF‑7 human breast cancer cells

Xian Zhang, Yang Zhang, Yinghua Li
Article Number: 34
Published online on: 18 December 2025

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Research progress on the regulation of ferroptosis in NPC (Review)

Shuai Bai, Yanjie Guo, Jingling Qiang, Qiangfang Dai, Yanling Yang
Article Number: 33
Published online on: 18 December 2025

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[Retracted] Platelet‑derived growth factor BB mediates the glioma‑induced migration of bone marrow‑derived mesenchymal stem cells by promoting the expression of vascular cell adhesion molecule‑1 through the PI3K, P38 MAPK and NF‑κB pathways

Yi Hu, Peng Cheng, Jiang-Chun Ma, Yi-Xue Xue, Yun-Hui Liu
Article Number: 32
Published online on: 08 December 2025

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Alternative splicing in cancer drug resistance: Mechanisms and therapeutic prospects (Review)

Wenpu Zhu, Zikun Wu, Chai Luv, Banghe Bao, Weijie Zhao, Guanglong Chen, Hang Yang, Huihan Ai, Faqiang Liu, Zhi Li
Article Number: 31
Published online on: 05 December 2025

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Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells

Liangliang Jin, Li Wei, Junrui Hua, Rong Zhang, Jiaxin Chen, Jinpeng He, Yanli Yang
Article Number: 30
Published online on: 04 December 2025

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Beyond eradication: Therapeutic reprogramming strategies for cancer normalization (Review)

Aliasgar Shahiwala
Article Number: 29
Published online on: 04 December 2025

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Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy

Rui Zheng, Yusi Liu, Sen Zhou, Guimei Liu, Xiaobin Liu, Yiyuan Yang, Yufu Zhang
Article Number: 28
Published online on: 04 December 2025

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[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Article Number: 27
Published online on: 04 December 2025

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Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma

Yuto Kitano, Tomoharu Miyashita, Takeo Shimasaki, Isamu Makino, Yoshio Endo, Yasuhiko Yamamoto, Noriyuki Inaki, Shintaro Yagi
Article Number: 26
Published online on: 03 December 2025

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[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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Journal Cover
March-2026 Volume 55 Issue 3

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

GPR176 enhances the epithelial‑mesenchymal transition in gastric cancer cells by activating the PI3K/AKT/mTOR signaling pathway

Guangchuan Mu, Kaiyan Li, Chaozhen Hu, Jintao Cai, Huichao Ruan, Guanyu Zhu, Dang Liu
Article Number: 48
Published online on: 19 January 2026

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HMBOX1 inhibits hepatocellular carcinoma progression via PTPN1 mediated AKT1 phosphorylation

Chenning Zhang, Yu Jiang, Jiahui Liu, Wenyu Zhang, Jie Qi, Qing Wen, Hengli Zhao
Article Number: 47
Published online on: 19 January 2026

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[Retracted] Prognostic significance of miR‑218 in human hepatocellular carcinoma and its role in cell growth

Kangsheng Tu, Chao Li, Xin Zheng, Wei Yang, Yingmin Yao, Qingguang Liu
Article Number: 46
Published online on: 19 January 2026

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Tumor microenvironment in bone sarcomas: Implications for immunotherapy and emerging therapeutic vulnerabilities (Review)

Wentao Li, Lijun Lv, Yibin Jin, Xin Yuan
Article Number: 45
Published online on: 16 January 2026

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Immunotherapy after EGFR‑TKI treatment in advanced non‑small cell lung cancer: Current status and future perspectives (Review)

Huiyuan Ma, Longhui Li, Conghan Jiao, Yanyan Cheng, Jiayu He, Chen Jiang, Qian Tong, Dan Yi, Ying Zhang
Article Number: 44
Published online on: 16 January 2026

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[Corrigendum] Triptolide inhibits JAK2/STAT3 signaling and induces lethal autophagy through ROS generation in cisplatin‑resistant SKOV3/DDP ovarian cancer cells

Yanying Zhong, Fuyin Le, Jiao Cheng, Chen Luo, Xiali Zhang, Xingwu Wu, Fang Xu, Qi Zuo, Buzhen Tan
Article Number: 43
Published online on: 13 January 2026

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Role of tumor‑infiltrating lymphocytes and miR‑155 in breast cancer: Insights into carcinogenesis and their potential as prognostic biomarkers (Review)

Miriam Monteiro Alvares‑Vilela, Franciele Schlemmer, Sabrina Simplício De Araújo Romero Ferrari, Mary-Ann Elvina Xavier, Ricardo Titze‑De‑Almeida
Article Number: 42
Published online on: 14 January 2026

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CDK1 depletion suppresses glioma malignancy through cell cycle pathway regulation: Mechanistic insights from functional and molecular profiling

Yu Wang, Huandi Zhou, Xuetao Han, Dongdong Zhang, Liubing Hou, Haonan Li, Tianyi Fan, Sijie Li, Xiaoying Xue
Article Number: 41
Published online on: 12 January 2026

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[Retracted] Downregulated microRNA‑200a promotes EMT and tumor growth through the Wnt/β‑catenin pathway by targeting the E‑cadherin repressors ZEB1/ZEB2 in gastric adenocarcinoma

Ningning Cong, Ping Du, Anling Zhang, Fajuan Shen, Juan Su, Peiyu Pu, Tao Wang, Jie Zjang, Chunsheng Kang, Qingyu Zhang
Article Number: 40
Published online on: 12 January 2026

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Advances in targeting KRAS mutations: A promising approach for the treatment of non‑small cell lung cancer (Review)

Upesh Sharma, Jincheng Song, Hemraj Kandu, Yue Zhu, Zhaoxia Dai
Article Number: 39
Published online on: 08 January 2026

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[Corrigendum] CXCR6 predicts poor prognosis in gastric cancer and promotes tumor metastasis through epithelial-mesenchymal transition

Jie-Jie Jin, Fa-Xiang Dai, Zi-Wen Long, Hong Cai, Xiao-Wen Liu, Ye Zhou, Qi Hong, Qiong-Zhu Dong, Ya-Nong Wang, Hua Huang
Article Number: 38
Published online on: 05 January 2026

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