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Oncology Reports
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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
August-2018 Volume 40 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

MicroRNA‑92a‑3p inhibits the cell proliferation, migration and invasion of Wilms tumor by targeting NOTCH1

Shibo Zhu, Liyu Zhang, Zhang Zhao, Wen Fu, Kai Fu, Guochang Liu, Wei Jia
Pages: 571-578
Published online on: 23 May 2018

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Article Open Access

Genistein and AG1024 synergistically increase the radiosensitivity of prostate cancer cells

Qisheng Tang, Jianjun Ma, Jinbo Sun, Longfei Yang, Fan Yang, Wei Zhang, Ruixiao Li, Lei Wang, Yong Wang, He Wang
Pages: 579-588
Published online on: 30 May 2018

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Article Open Access

miR‑1 inhibits the progression of colon cancer by regulating the expression of vascular endothelial growth factor

Dehua Zhu, Yefei Sun, Danhua Zhang, Ming Dong, Guiyang Jiang, Xiupeng Zhang, Jianping Zhou
Pages: 589-598
Published online on: 24 May 2018

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Article Open Access

Girdin regulates the proliferation and apoptosis of pancreatic cancer cells via the PI3K/Akt signalling pathway

Sheng Wang, Yiqun Lei, Zeling Cai, Xiaoman Ye, Lianhong Li, Xiagang Luo, Chunzhao Yu
Pages: 599-608
Published online on: 31 May 2018

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Article Open Access

Norcantharidin reverses cisplatin resistance and inhibits the epithelial mesenchymal transition of human non‑small lung cancer cells by regulating the YAP pathway Retraction in /10.3892/or.2020.7830

Dan Jin, Yan Wu, Cuijie Shao, Yong Gao, Deqiang Wang, Jiwei Guo
Pages: 609-620
Published online on: 12 June 2018

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Article Open Access

Proliferative role of BDNF/TrkB signaling is associated with anoikis resistance in cervical cancer

Yuan Yuan, Hai‑Qiong Ye, Qian‑Chuan Ren
Pages: 621-634
Published online on: 20 June 2018

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Article Open Access

Evaluation of anticancer agents using patient-derived tumor organoids characteristically similar to source tissues

Hirosumi Tamura, Arisa Higa, Hirotaka Hoshi, Gen Hiyama, Nobuhiko Takahashi, Masae Ryufuku, Gaku Morisawa, Yuka Yanagisawa, Emi Ito, Jun-Ichi Imai, Yuu Dobashi, Kiyoaki Katahira, Shu Soeda, Takafumi Watanabe, Keiya Fujimori, Shinya Watanabe, Motoki Takagi
Pages: 635-646
Published online on: 18 June 2018

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Article Open Access

Aberrantly expressed genes and miRNAs in human hypopharyngeal squamous cell carcinoma based on RNA‑sequencing analysis

Hu Li, Fuling Wang, Yonghua Fei, Yanhua Lei, Fengxiang Lu, Ping Guo, Wei Li, Xuehong Xun
Pages: 647-658
Published online on: 19 June 2018

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Article Open Access

Diagnostic value and lymph node metastasis prediction of a custom‑made panel (thyroline) in thyroid cancer

Zunfu Ke, Yihao Liu, Yunjian Zhang, Jie Li, Ming Kuang, Sui Peng, Jinyu Liang, Shuang Yu, Lei Su, Lili Chen, Cong Sun, Bin Li, Jessica Cao, Weiming Lv, Haipeng Xiao
Pages: 659-668
Published online on: 14 June 2018

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Article Open Access

Novel triple‑positive markers identified in human non‑small cell lung cancer cell line with chemotherapy-resistant and putative cancer stem cell characteristics

Nazilah Abdul Satar, Kamal Shaik Fakiruddin, Moon Nian Lim, Pooi Ling Mok, Norashikin Zakaria, Noor Atiqah Fakharuzi, Ahmad Zuhairi Abd Rahman, Zubaidah Zakaria, Badrul Hisham Yahaya, Puteri Baharuddin
Pages: 669-681
Published online on: 24 May 2018

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Article Open Access

HSV‑TK/GCV can induce cytotoxicity of retinoblastoma cells through autophagy inhibition by activating MAPK/ERK

Quan‑Yong Yi, Zhi‑Sha Bai, Bin Cai, Nan Chen, Li‑Shuang Chen, Tao Yuan, Jing‑Hai Mao
Pages: 682-692
Published online on: 21 May 2018

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Article Open Access

E‑cadherin regulates proliferation of colorectal cancer stem cells through NANOG

Shingo Tamura, Taichi Isobe, Hiroshi Ariyama, Michitaka Nakano, Yoshikane Kikushige, Shigeo Takaishi, Hitoshi Kusaba, Katsuto Takenaka, Takashi Ueki, Masafumi Nakamura, Koichi Akashi, Eishi Baba
Pages: 693-703
Published online on: 24 May 2018

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Article Open Access

Fibroblast growth factor 18 promotes the growth, migration and invasion of MDA‑MB‑231 cells

Ziyi Yu, Longquan Lou, Yi Zhao
Pages: 704-714
Published online on: 07 June 2018

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Article Open Access

Identification of the potential oncogenes in glioblastoma based on bioinformatic analysis and elucidation of the underlying mechanisms

Yong Zhang, Qiming Xia, Jun Lin
Pages: 715-725
Published online on: 11 June 2018

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Article Open Access

SB225002 inhibits prostate cancer invasion and attenuates the expression of BSP, OPN and MMP‑2

Meng Xu, Huamao Jiang, Haiguang Wang, Jiajie Liu, Baohao Liu, Zhongqiang Guo
Pages: 726-736
Published online on: 18 June 2018

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Article Open Access

Osthole enhances antitumor activity and irradiation sensitivity of cervical cancer cells by suppressing ATM/NF‑κB signaling

Yilin Che, Juan Li, Zongjuan Li, Jing Li, Shuai Wang, Ying Yan, Kun Zou, Lijuan Zou
Pages: 737-747
Published online on: 20 June 2018

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Article

Aberrant expression of FoxP3 in a human T cell line possessing regulatory T cell‑like function and exposed continuously to asbestos fibers

Megumi Maeda, Hidenori Matsuzaki, Shoko Yamamoto, Suni Lee, Naoko Kumagai‑Takei, Kei Yoshitome, Yu Min, Nagisa Sada, Yasumitsu Nishimura, Takemi Otsuki
Pages: 748-758
Published online on: 07 June 2018

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Article

Trop2 is a potential biomarker for the promotion of EMT in human breast cancer

Wei Zhao, Xingwang Kuai, Xueyi Zhou, Lizhou Jia, Jinsong Wang, Xiaobing Yang, Zhidan Tian, Xiaolei Wang, Qian Lv, Bin Wang, Youcai Zhao, Wenbin Huang
Pages: 759-766
Published online on: 14 June 2018

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Article

MicroRNA-152 inhibits cell proliferation of osteosarcoma by directly targeting Wnt/β-catenin signaling pathway in a DKK1-dependent manner

Xin Zhao, Shicai Sun, Jianting Xu, Yang Luo, Ying Xin, Yanbing Wang
Pages: 767-774
Published online on: 22 May 2018

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Article

Preliminary mechanisms of regulating PD‑L1 expression in non‑small cell lung cancer during the EMT process

Fang Li, Tengjiao Zhu, Yao Yue, Xiang Zhu, Jiadong Wang, Li Liang
Pages: 775-782
Published online on: 05 June 2018

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Article Open Access

Sperm‑associated antigen 4 (SPAG4) as a new cancer marker interacts with Nesprin3 to regulate cell migration in lung carcinoma

Ying Ji, Jinquan Jiang, Lihua Huang, Wei Feng, Zhang Zhang, Longyu Jin, Xiaowei Xing
Pages: 783-792
Published online on: 04 June 2018

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Article

Overexpression of miR-140-5p inhibits lipopolysaccharide-induced human intervertebral disc inflammation and degeneration by downregulating toll-like receptor 4

Qiang Zhang, Yiping Weng, Yuqing Jiang, Shujie Zhao, Dong Zhou, Nanwei Xu
Pages: 793-802
Published online on: 12 June 2018

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Article

Timed‑flat infusion of 5‑fluorouracil with docetaxel and oxaliplatin as first‑line treatment of gastroesophageal adenocarcinoma: A single institution experience with the FD/FOx regimen

Alessio Cortellini, Katia Cannita, Alessandro Parisi, Olga Venditti, Paola Lanfiuti Baldi, Berardo De Berardis, Roberto Vicentini, Vincenzo Vicentini, Lucilla Verna, Giampiero Porzio, Corrado Ficorella
Pages: 803-812
Published online on: 06 June 2018

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Article

shRNA‑induced knockdown of the SPERT gene inhibits proliferation and promotes apoptosis of human colorectal cancer RKO cells

Long‑Zhi Zheng, Si‑Zeng Chen
Pages: 813-822
Published online on: 21 May 2018

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Article

Estrogen‑related receptor γ promotes the migration and metastasis of endometrial cancer cells by targeting S100A4

Teng Hua, Xiaoxiao Wang, Shuqi Chi, Yan Liu, Dilu Feng, Yingchao Zhao, Hongbo Wang
Pages: 823-832
Published online on: 04 June 2018

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Article

RAD52 motif‑containing protein 1 promotes non‑small cell lung cancer cell proliferation and survival via cell cycle regulation

Guihua Xu, Jiya Du, Feng Wang, Fan Zhang, Ruimin Hu, Dejun Sun, Jie Shen
Pages: 833-840
Published online on: 23 May 2018

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Article

Cdc20 inhibitor apcin inhibits the growth and invasion of osteosarcoma cells

Yuan Gao, Benyuan Zhang, Yuming Wang, Guanning Shang
Pages: 841-848
Published online on: 30 May 2018

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Article

MicroRNA‑320a suppresses tumor cell growth and invasion of human breast cancer by targeting insulin‑like growth factor 1 receptor

Jinghong Guan, Yidong Zhou, Feng Mao, Yan Lin, Songjie Shen, Yanna Zhang, Qiang Sun
Pages: 849-858
Published online on: 20 June 2018

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Article

Long non-coding RNA BANCR regulates cancer stem cell markers in papillary thyroid cancer via the RAF/MEK/ERK signaling pathway

Yuanyuan Wang, Xiangde Lin, Xinghao Fu, Wei Yan, Fusheng Lin, Penghao Kuang, Yezhe Luo, Ende Lin, Xiaoquan Hong, Guoyang Wu
Pages: 859-866
Published online on: 18 June 2018

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Article

Oxymatrine induces cell cycle arrest and apoptosis and suppresses the invasion of human glioblastoma cells through the EGFR/PI3K/Akt/mTOR signaling pathway and STAT3

Zhibo Dai, Ligang Wang, Xiaoxiong Wang, Boxian Zhao, Wenyang Zhao, Shashank Singh Bhardwaj, Junyi Ye, Zhiqin Yin, Jun Zhang, Shiguang Zhao
Pages: 867-876
Published online on: 20 June 2018

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Article

Salinomycin induces apoptosis and differentiation in human acute promyelocytic leukemia cells

Yi Zhao, Liang Zhong, Lu Liu, Shi-Fei Yao, Min Chen, Lian-Wen Li, Zhi-Ling Shan, Chun-Lan Xiao, Liu-Gen Gan, Ting Xu, Bei-Zhong Liu
Pages: 877-886
Published online on: 20 June 2018

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Article

Silencing of Girdin suppresses the malignant behavior of colorectal carcinoma cells

Jia Lu, Lin Zhang, Hongyan Zhou, Zhenwu Du, Guizhen Zhang
Pages: 887-894
Published online on: 20 June 2018

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Article

Curcumin inhibits liver cancer by inhibiting DAMP molecule HSP70 and TLR4 signaling

Biqiong Ren, Shudi Luo, Xuefei Tian, Zhichao Jiang, Guoying Zou, Fei Xu, Tieqiu Yin, Yiran Huang, Junlong Liu
Pages: 895-901
Published online on: 11 June 2018

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Article

Montelukast, a cysteinyl leukotriene receptor antagonist, inhibits the growth of chronic myeloid leukemia cells through apoptosis

Ana Zovko, Elham Yektaei-Karin, Daniel Salamon, Anders Nilsson, Jonas Wallvik, Leif Stenke
Pages: 902-908
Published online on: 25 May 2018

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Article

Alternative splicing variant of RHBDD2 is associated with cell stress response and breast cancer progression

Romina Canzoneri, Martín Enrique Rabassa, Agustina Gurruchaga, Valeria Ferretti, Sabina Palma, Marina Isla‑Larrain, María Virginia Croce, Ezequiel Lacunza, Martín Carlos Abba
Pages: 909-915
Published online on: 14 June 2018

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Article

miR‑218 promotes apoptosis of SW1417 human colon cancer cells by targeting c‑FLIP

Qingkai Meng, Yue Chen, Bo Lian, Yan Shang, Hongmei Yang
Pages: 916-922
Published online on: 23 May 2018

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Article

Elevated TFAP4 regulates lncRNA TRERNA1 to promote cell migration and invasion in gastric cancer

Huazhang Wu, Xiufang Liu, Pihai Gong, Wei Song, Menghan Zhou, Yiping Li, Zhujiang Zhao, Hong Fan
Pages: 923-931
Published online on: 25 May 2018

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Article

Lysyl oxidase-like 2 is highly expressed in colorectal cancer cells and promotes the development of colorectal cancer

Ximao Cui, Guanghui Wang, Wenbin Shen, Zhenyu Huang, Hailan He, Long Cui
Pages: 932-942
Published online on: 21 May 2018

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Article

miR‑150 promotes the proliferation and migration of non‑small cell lung cancer cells by regulating the SIRT2/JMJD2A signaling pathway

Kanqiu Jiang, Mingjing Shen, Yongbing Chen, Weihua Xu
Pages: 943-951
Published online on: 12 June 2018

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Article

Insulin-like growth factor-1 induces epithelial-mesenchymal transition in hepatocellular carcinoma by activating survivin

Fangfeng Liu, Yongjie Sun, Bingqi Liu, Jun Lu, Hongguang Li, Huaqiang Zhu, Hengjun Gao, Xu Zhou, Hong Chang
Pages: 952-958
Published online on: 20 June 2018

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Article

Prognostic signatures for renal cancer as identified by long non-coding and miRNA competing endogenous network analysis.

Hongwei Gao, Xuanrong Chen, Zhiqun Shang, Yuanjie Niu
Pages: 959-967
Published online on: 06 June 2018

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Article

DKC1 serves as a potential prognostic biomarker for human clear cell renal cell carcinoma and promotes its proliferation, migration and invasion via the NF‑κB pathway

Meng Zhang, Yu Pan, Ranran Jiang, Pingfu Hou, Haixia Shan, Fang Chen, Tao Jiang, Jin Bai, Junnian Zheng
Pages: 968-978
Published online on: 11 June 2018

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Article

Oct4 promotes cancer cell proliferation and migration and leads to poor prognosis associated with the survivin/STAT3 pathway in hepatocellular carcinoma

Gang Wang, Hemei Zhou, Zhigang Gu, Quangen Gao, Genhai Shen
Pages: 979-987
Published online on: 14 June 2018

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Article

XBP1 promotes tumor invasion and is associated with poor prognosis in oral squamous cell carcinoma

Yanan Sun, Fangyan Jiang, Yuemei Pan, Xinming Chen, Jirong Chen, Yu Wang, Xueqing Zheng, Jiali Zhang
Pages: 988-998
Published online on: 18 June 2018

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Article

γ-tocotrienol inhibits the invasion and migration of human gastric cancer cells through downregulation of cyclooxygenase-2 expression

Ya Hui Zhang, Ke Ma, Jia Ren Liu, Hai Xia Wang, Wen Xia Tian, Yue Hua Tu, Wen Guang Sun
Pages: 999-1007
Published online on: 14 June 2018

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Article

Association between methylation of tumor suppressor gene SOCS1 and acute myeloid leukemia

Xiao‑Hui Zhang, Lin Yang, Xiao‑Jun Liu, Ying Zhan, Yu‑Xia Pan, Xing‑Zhe Wang, Jian‑Min Luo
Pages: 1008-1016
Published online on: 19 June 2018

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Article

Enhanced expression of SETDB1 possesses prognostic value and promotes cell proliferation, migration and invasion in nasopharyngeal carcinoma

Jing Huang, Weiyuan Huang, Mei Liu, Jianping Zhu, Danxian Jiang, Yinghuan Xiong, Yan Zhen, Donghong Yang, Zihong Chen, Lijiao Peng, Zhonghua Yu
Pages: 1017-1025
Published online on: 14 June 2018

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Article

LC‑MS/MS metabolome analysis detects the changes in the lipid metabolic profiles of dMMR and pMMR cells

Wen Peng, Shisheng Tan, Youzhi Xu, Liang Wang, Dong Qiu, Chan Cheng, Yiyun Lin, Chunqi Liu, Zhuolin Li, Yan Li, Yinglan Zhao, Qiu Li
Pages: 1026-1034
Published online on: 20 June 2018

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Article

HBsAg/β2GPI activates the NF‑κB pathway via the TLR4/MyD88/IκBα axis in hepatocellular carcinoma

Xue Jing, Zibin Tian, Pujun Gao, Huashi Xiao, Xiaolong Qi, Yanan Yu, Xueli Ding, Lin Yang, Liang Zong
Pages: 1035-1045
Published online on: 19 June 2018

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Article

A novel strategy of EGFR‑TKI combined chemotherapy in the treatment of human lung cancer with EGFR‑sensitive mutation

Lanlin Zhang, Yuan Qi, Kailin Xing, Song Qian, Ping Zhang, Xianghua Wu
Pages: 1046-1054
Published online on: 18 June 2018

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Article

Fabrication of psoralen-loaded lipid-polymer hybrid nanoparticles and their reversal effect on drug resistance of cancer cells

Yueling Yuan, Peter Chiba, Tiange Cai, Richard Callaghan, Li Bai, Susan P.C. Cole, Yu Cai
Pages: 1055-1063
Published online on: 14 June 2018

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Article

A novel biphenyl urea compound, TPD7, stimulates apoptosis through modulating Fas signaling and Bcl-2 family proteins in cervical cancer

Yingzhuan Zhan, Han Zhang, Bingling Dai, Yanmin Zhang, Jie Zhang, Langchong He
Pages: 1064-1072
Published online on: 04 June 2018

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Article

Protein kinase D1 regulates hypoxic metabolism through HIF-1α and glycolytic enzymes incancer cells

Jiao Chen, Bomiao Cui, Yaping Fan, Xiaoying Li, Qian Li, Yue Du, Yun Feng, Ping Zhang
Pages: 1073-1082
Published online on: 07 June 2018

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Article

Dual mTOR/PI3K inhibitor NVP‑BEZ235 arrests colorectal cancer cell growth and displays differential inhibition of 4E‑BP1

Naif Alqurashi, Saeed M. Hashimi, Faisal Alowaidi, Saso Ivanovski, Ming Q. Wei
Pages: 1083-1092
Published online on: 22 May 2018

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Article

Long non‑coding RNA PVT1 promotes epithelial‑mesenchymal transition via the TGF‑β/Smad pathway in pancreatic cancer cells

Xingxing Zhang, Wen Feng, Jin Zhang, Lu Ge, Youli Zhang, Xiaomeng Jiang, Wanxin Peng, Dawei Wang, Aihua Gong, Min Xu
Pages: 1093-1102
Published online on: 24 May 2018

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Article

Systems biology analysis of the lung cancer‑related secretome

Lin Feng, Yikun Yang, Min Li, Jie Song, Yanning Gao, Shujun Cheng, Ting Xiao
Pages: 1103-1118
Published online on: 20 June 2018

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Article

uc.338 targets p21 and cyclin D1 via PI3K/AKT pathway activation to promote cell proliferation in colorectal cancer

Yue Zhang, Shijia Wang, Wenwei Qian, Dongjian Ji, Qingyuan Wang, Zhiyuan Zhang, Sen Wang, Bing Ji, Zan Fu, Yueming Sun
Pages: 1119-1128
Published online on: 07 June 2018

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Article

Luteolin reduces cancer‑induced skeletal and cardiac muscle atrophy in a Lewis lung cancer mouse model

Tiejun Chen, Bin Li, Ye Xu, Shuying Meng, Yuan Wang, Yan Jiang
Pages: 1129-1137
Published online on: 21 May 2018

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Article

Upregulated miR‑20a‑5p expression promotes proliferation and invasion of head and neck squamous cell carcinoma cells by targeting of TNFRSF21

Hong Wu, Pai Pang, Min‑Da Liu, Song Wang, Shan Jin, Fa‑Yu Liu, Chang‑Fu Sun
Pages: 1138-1146
Published online on: 07 June 2018

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G‑protein‑coupled receptor 120 regulates the development and progression of human esophageal cancer

Zhen Cui, Duojie Li, Jingjing Liu, Yajun Zhang, Hongbo Xu, Hongmei Yin, Hongwei Li, Gengming Wang, Hanfei Cai, Lei Zhang, Shimiao Duan, Hao Jiang
Pages: 1147-1155
Published online on: 31 May 2018

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AAED1 modulates proliferation and glycolysis in gastric cancer

Beili Zhang, Jugang Wu, Yantao Cai, Meng Luo, Bing Wang, Yan Gu
Pages: 1156-1164
Published online on: 07 June 2018

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Wnt signaling pathway upregulates DNMT1 to trigger NHERF1 promoter hypermethylation in colon cancer

Yongli Guo, Meng Wang, Xuefeng Jia, Hua Zhu, Yaqin Zhi, Leilei Yuan
Pages: 1165-1173
Published online on: 14 June 2018

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Androgen receptor induces EPHA3 expression by interacting with transcription factor SP1

Xiaowei Diao, Xiubin Chen, Yurui Pi, Yu Zhang, Fangfang Wang, Ping Liu, Yanhong Gao, Xiaojun Wang, Sijun Yang, Shan Lu
Pages: 1174-1184
Published online on: 18 June 2018

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HGF derived from cancer‑associated fibroblasts promotes vascularization in gastric cancer via PI3K/AKT and ERK1/2 signaling

Xusheng Ding, Wenqi Xi, Jun Ji, Qu Cai, Jinling Jiang, Min Shi, Yingyan Yu, Zhenggang Zhu, Jun Zhang
Pages: 1185-1195
Published online on: 18 June 2018

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Correction Open Access

[Corrigendum] LSD1 negatively regulates autophagy through the mTOR signaling pathway in ovarian cancer cells

Ye Wei, Tiantian Han, Ranran Wang, Jing Wei, Ke Peng, Qiong Lin, Genbao Shao
Pages: 1196-1196
Published online on: 14 June 2018

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Correction Open Access

[Corrigendum] Bioinformatics analysis of differentially expressed miRNA‑related mRNAs and their prognostic value in breast carcinoma

Guo-Ming Zhang, Hemant Goyal, Lei-Lei Song
Pages: 1197-1197
Published online on: 19 June 2018

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Journal Cover
March-2026 Volume 55 Issue 3

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Collaborative breakthroughs in precision diagnosis and treatment of nasopharyngeal cancer: Biomarker‑driven screening and endoscopic minimally invasive surgery reshape the new paradigm of early intervention (Review)

E Jin, Wang Lin, Xiandong Zeng
Article Number: 53
Published online on: 23 January 2026

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Key immune cells in the tumor immune microenvironment of colorectal cancer: Roles and research advances (Review)

Ming Qiu, Chongyuan Lan, Minglin Lin, Hui Ma
Article Number: 52
Published online on: 21 January 2026

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Correction Open Access

[Corrigendum] Icaritin acts synergistically with epirubicin to suppress bladder cancer growth through inhibition of autophagy

Xiu-Wu Pan, Lin Li, Yi Huang, Hai Huang, Dan-Feng Xu, Yi Gao, Lu Chen, Ji-Zhong Ren, Jian-Wei Cao, Yi Hong, Xin-Gang Cui
Article Number: 51
Published online on: 21 January 2026

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Epigenetic mechanisms and therapeutic advances in diffuse midline glioma (Review)

Wenbo Wu, Wenlin Chen, Wenbin Ma, Yu Wang
Article Number: 50
Published online on: 20 January 2026

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Review Open Access

Recapitulating lung cancer metastasis in vitro: Advances in organoid models and challenges in clinical translation (Review)

Jian Jiang, Guomin Dong, Zhiyun Zhang, Xiaoyuan Lei, Fanshu Huang, Suoni Li, Jiequn Ma, Jie Bai, Qian Ge, Hui Wei, Zheng Zhao
Article Number: 49
Published online on: 20 January 2026

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GPR176 enhances the epithelial‑mesenchymal transition in gastric cancer cells by activating the PI3K/AKT/mTOR signaling pathway

Guangchuan Mu, Kaiyan Li, Chaozhen Hu, Jintao Cai, Huichao Ruan, Guanyu Zhu, Dang Liu
Article Number: 48
Published online on: 19 January 2026

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HMBOX1 inhibits hepatocellular carcinoma progression via PTPN1 mediated AKT1 phosphorylation

Chenning Zhang, Yu Jiang, Jiahui Liu, Wenyu Zhang, Jie Qi, Qing Wen, Hengli Zhao
Article Number: 47
Published online on: 19 January 2026

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[Retracted] Prognostic significance of miR‑218 in human hepatocellular carcinoma and its role in cell growth

Kangsheng Tu, Chao Li, Xin Zheng, Wei Yang, Yingmin Yao, Qingguang Liu
Article Number: 46
Published online on: 19 January 2026

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Review Open Access

Tumor microenvironment in bone sarcomas: Implications for immunotherapy and emerging therapeutic vulnerabilities (Review)

Wentao Li, Lijun Lv, Yibin Jin, Xin Yuan
Article Number: 45
Published online on: 16 January 2026

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Immunotherapy after EGFR‑TKI treatment in advanced non‑small cell lung cancer: Current status and future perspectives (Review)

Huiyuan Ma, Longhui Li, Conghan Jiao, Yanyan Cheng, Jiayu He, Chen Jiang, Qian Tong, Dan Yi, Ying Zhang
Article Number: 44
Published online on: 16 January 2026

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Correction Open Access

[Corrigendum] Triptolide inhibits JAK2/STAT3 signaling and induces lethal autophagy through ROS generation in cisplatin‑resistant SKOV3/DDP ovarian cancer cells

Yanying Zhong, Fuyin Le, Jiao Cheng, Chen Luo, Xiali Zhang, Xingwu Wu, Fang Xu, Qi Zuo, Buzhen Tan
Article Number: 43
Published online on: 13 January 2026

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Role of tumor‑infiltrating lymphocytes and miR‑155 in breast cancer: Insights into carcinogenesis and their potential as prognostic biomarkers (Review)

Miriam Monteiro Alvares‑Vilela, Franciele Schlemmer, Sabrina Simplício de Araújo Romero Ferrari, Mary-Ann Elvina Xavier, Ricardo Titze‑de‑Almeida
Article Number: 42
Published online on: 14 January 2026

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Article Open Access

CDK1 depletion suppresses glioma malignancy through cell cycle pathway regulation: Mechanistic insights from functional and molecular profiling

Yu Wang, Huandi Zhou, Xuetao Han, Dongdong Zhang, Liubing Hou, Haonan Li, Tianyi Fan, Sijie Li, Xiaoying Xue
Article Number: 41
Published online on: 12 January 2026

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Retraction Open Access

[Retracted] Downregulated microRNA‑200a promotes EMT and tumor growth through the Wnt/β‑catenin pathway by targeting the E‑cadherin repressors ZEB1/ZEB2 in gastric adenocarcinoma

Ningning Cong, Ping Du, Anling Zhang, Fajuan Shen, Juan Su, Peiyu Pu, Tao Wang, Jie Zjang, Chunsheng Kang, Qingyu Zhang
Article Number: 40
Published online on: 12 January 2026

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Advances in targeting KRAS mutations: A promising approach for the treatment of non‑small cell lung cancer (Review)

Upesh Sharma, Jincheng Song, Hemraj Kandu, Yue Zhu, Zhaoxia Dai
Article Number: 39
Published online on: 08 January 2026

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[Corrigendum] CXCR6 predicts poor prognosis in gastric cancer and promotes tumor metastasis through epithelial-mesenchymal transition

Jie-Jie Jin, Fa-Xiang Dai, Zi-Wen Long, Hong Cai, Xiao-Wen Liu, Ye Zhou, Qi Hong, Qiong-Zhu Dong, Ya-Nong Wang, Hua Huang
Article Number: 38
Published online on: 05 January 2026

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Journal Cover
April-2026 Volume 55 Issue 4

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

Quercetin reduces expression of ATP‑binding cassette transporters by regulating the PTEN/PI3K/AKT signaling pathway in breast cancer cells

Wentao Fu, Leying Lin, Jie Li, Fei Qin, Chuan Chen, Yinglian Cai, Yilun Cai, Yiling Huang, Wang Yang, Shanshan Zhu
Article Number: 63
Published online on: 02 February 2026

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POSTN+ fibroblast‑secreted small extracellular vesicles drive macrophage M2 polarization through BMP4/BMPR2/Smad signaling

Chenyang Zhang, Si Chen, Chenghui Qian, Wanqi Lv, Qian Zhang, Yanjin Wang, Yuqiong Wu, Xue Liu
Article Number: 62
Published online on: 02 February 2026

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[Retracted] EGFR/HER2 inhibitors effectively reduce the malignant potential of MDR breast cancer evoked by P‑gp substrates in vitro and in vivo

Yiting Jin, Wei Zhang, Hongying Wang, Zijing Zhang, Chengyu Chu, Xiuping Liu, Qiang Zou
Article Number: 61
Published online on: 02 February 2026

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Tumor‑associated glucocorticoid inhibition by mifepristone reduces polymorphonuclear myeloid‑derived suppressor cells and promotes antitumor immunity in triple‑negative breast cancer‑bearing mice

Masato Kobayashi, Chisana Konno, Ayato Shimizu, Masanori Kobayashi, Tatsuya Hori
Article Number: 60
Published online on: 30 January 2026

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Review Open Access

Mitochondria in T‑cell tumor immunity and tumor therapies targeting mitochondria (Review)

Minjie Zhou, Yijie Xie, Zhipeng Liu, Yi He, Yibing Yin, Keyu Chen, Zhengyu Zhao, Chengshun Zhang, Dingjun Cai
Article Number: 59
Published online on: 29 January 2026

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TRIM46 deficiency‑induced DNA damage enhances the sensitivity of cisplatin in non‑small cell lung cancer by regulating the Akt signaling pathway

Song Jin, Dandan Zhang, Zhicheng Liao, Lingpei Yu, Yuanyuan Wang, Pengcheng Jia, Minmin Pan, Yifan Li, Jizhou Zhang
Article Number: 58
Published online on: 28 January 2026

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Advances in isolation and detection technologies and immunotherapy applications of circulating tumor cells (Review)

Ping Zhou, Qin Ye, Yiyun Huang, Yumei Feng, Li Zhou, Ke Xie
Article Number: 57
Published online on: 28 January 2026

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[Corrigendum] 3‑Bromopyruvate sensitizes human breast cancer cells to TRAIL‑induced apoptosis via the phosphorylated AMPK‑mediated upregulation of DR5

Yuzhong Chen, Li Wei, Xiaojing Zhang, Xianfu Liu, Yansong Chen, Song Zhang, Lanzhu Zhou, Qixiang Li, Qiong Pan, Surong Zhao, Hao Liu
Article Number: 56
Published online on: 28 January 2026

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High RMI1 expression is associated with cancer cell progression and poor prognosis in prostate cancer

Pengliang Shen, Xiaosong Wang, Xiaoting Yan, Hongyang Du, Bo Wu, Xiaoming Cao
Article Number: 55
Published online on: 27 January 2026

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[Retracted] MicroRNA‑615‑5p targets insulin‑like growth factor 2 and exerts tumor‑suppressing functions in human esophageal squamous cell carcinoma

Bingyin Yang, Rui Xie, Shang-Nong Wu, Cheng-Cheng Gao, Xiao-Zhong Yang, Jing-Fang Zhou
Article Number: 54
Published online on: 26 January 2026

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